Search of human proteins with 169213703

Search of human proteins with 169213703

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169213703 PREDICTED: hypothetical protein [Homo sapiens]
         (319 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169213703 PREDICTED: hypothetical protein [Homo sapiens]           663   0.0  
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    58   1e-08
gi|210032580 SET domain containing 1B [Homo sapiens]                   58   1e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   3e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   6e-08
gi|146134388 YLP motif containing 1 [Homo sapiens]                     52   5e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    52   7e-07
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         52   9e-07
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                51   2e-06
gi|11386183 WAS protein family, member 2 [Homo sapiens]                49   6e-06
gi|169207534 PREDICTED: hypothetical protein [Homo sapiens]            49   8e-06
gi|117938768 GNAS complex locus alex [Homo sapiens]                    48   1e-05
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    47   2e-05
gi|130502140 NEZHA isoform 2 [Homo sapiens]                            47   2e-05
gi|122937255 NEZHA isoform 1 [Homo sapiens]                            47   2e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        46   4e-05
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        46   4e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         46   5e-05
gi|71274152 hypothetical protein LOC388939 [Homo sapiens]              46   5e-05
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    45   7e-05
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    45   7e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             45   9e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    45   1e-04
gi|209413756 synapsin III isoform IIIg [Homo sapiens]                  44   2e-04
gi|209413752 synapsin III isoform IIIa [Homo sapiens]                  44   2e-04
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       44   2e-04
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       43   3e-04
gi|118402590 myosin XV [Homo sapiens]                                  43   4e-04
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...    43   4e-04
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...    43   4e-04

>gi|169213703 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 319

 Score =  663 bits (1710), Expect = 0.0
 Identities = 319/319 (100%), Positives = 319/319 (100%)

Query: 1   MDIPISPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAPSTGAS 60
           MDIPISPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAPSTGAS
Sbjct: 1   MDIPISPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAPSTGAS 60

Query: 61  TSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHPRCY 120
           TSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHPRCY
Sbjct: 61  TSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHPRCY 120

Query: 121 PPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLP 180
           PPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLP
Sbjct: 121 PPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLP 180

Query: 181 HPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAF 240
           HPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAF
Sbjct: 181 HPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAF 240

Query: 241 PVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSPPGFSFLRFRRFSSALSASPHGTL 300
           PVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSPPGFSFLRFRRFSSALSASPHGTL
Sbjct: 241 PVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSPPGFSFLRFRRFSSALSASPHGTL 300

Query: 301 GSAWLWVWLGPCLSPGELH 319
           GSAWLWVWLGPCLSPGELH
Sbjct: 301 GSAWLWVWLGPCLSPGELH 319


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 74/265 (27%), Positives = 94/265 (35%), Gaps = 44/265 (16%)

Query: 44  PGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQG--PASVRPP---STPH 98
           P + S   ++ P +  + S    R  PR+  +P + P   G Q   P  V PP   + P 
Sbjct: 228 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPA 286

Query: 99  LLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSS-----------DPP 147
           L   S+      SP+ P     PP   + P PPA   S       S            PP
Sbjct: 287 LGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346

Query: 148 ARPRLFRRASASPAQLRLP------SRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLK 201
             P       A PA L LP      S  AS   + L  P P +P  L    L    S   
Sbjct: 347 LSPLATPPPQAPPA-LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-- 403

Query: 202 LPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFP--------VPLGRPRLPPPV 253
              PPS P       + A F P ++PP  P   P + A P        VP   P  PP  
Sbjct: 404 ---PPSPP-------VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453

Query: 254 FGSTRPALASPPLLGSVRSVRLSPP 278
             +T P  A PPL      +   PP
Sbjct: 454 PSATPPPQAPPPLAAPPLQLAKPPP 478



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 66/244 (27%), Positives = 89/244 (36%), Gaps = 35/244 (14%)

Query: 38  KFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTP 97
           K + L  G         P T +     R R     +G P   P        A  RPP+  
Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP-------SARPRPPTEG 195

Query: 98  HLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARP--RLFRR 155
              S S+ S    +   P  R  P       RP +   S++A   SS   + P  R   R
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255

Query: 156 ASASPAQLRLPSRLASALSAQLRLPH-PSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFS 214
           A A P+Q + P  L +    Q+  P   ++P + P     LS S L  P P + P    S
Sbjct: 256 APAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGP-----LSSSPLATPSPSAPP----S 305

Query: 215 AALPAAFRPCSAPPAW-PRLLPLALAFPV-----------PLGRPRLPPPVFGSTRPALA 262
            + P + +   +PPA  P     +L  P            PL     PPP      PALA
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP---QAPPALA 362

Query: 263 SPPL 266
            PPL
Sbjct: 363 LPPL 366



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 66/233 (28%), Positives = 77/233 (33%), Gaps = 61/233 (26%)

Query: 56  STGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPAS-------VRPPSTPHLLSASALSAQ 108
           S   S S T P   P SL  P   PL +    PAS         PP  P  L+A  L   
Sbjct: 418 SPPVSPSATPPSQAPPSLAAP---PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474

Query: 109 LDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSR 168
              P  P     PP   + P PPA       F  S+  P  P                  
Sbjct: 475 KPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSP------------------ 515

Query: 169 LASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPP 228
                   L  P P +P VL    L +       P PP+ P       L A  RP +  P
Sbjct: 516 --------LATPPPQAPPVLAAPLLQVP------PSPPASP------TLQAPRRPPTPGP 555

Query: 229 ----AWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSP 277
               + PR L LALA       P  PPP   S    L+ P L G   S   +P
Sbjct: 556 DTSVSGPR-LTLALA-------PGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 600


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 76/259 (29%), Positives = 88/259 (33%), Gaps = 39/259 (15%)

Query: 54   APSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPA 113
            AP       P  P +LP  L  PL  P     + P    PP  P    AS  S   +  A
Sbjct: 1259 APEHDLEVEPEPPMMLPLPLQPPLPPP-----RPPRPPSPPPEPETTDASHPSVPPEPLA 1313

Query: 114  RPHPRCYPPFALSAPR--------------PPALGASATAFRSSSDPPARPRLFRRASAS 159
              HP   P    S  +              PP  G S+    SS   P  P  +   S S
Sbjct: 1314 EDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPS 1373

Query: 160  PAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLK-------------LPLPP 206
             +   LP       S       PS P +LP   L     D +             LPLP 
Sbjct: 1374 LSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPL 1433

Query: 207  SWPWLGFSAALPAAFR-PCSAPPAWPRLLPLALA-FPVPL----GRPRLPPPVFGSTRPA 260
              P L    ALPA  R    AP   P LLP  LA  P P+    GRPR  PP   S    
Sbjct: 1434 PLP-LPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP 1492

Query: 261  LASPPLLGSVRSVRLSPPG 279
            L  PP   ++    L  PG
Sbjct: 1493 LVRPPAGAALGRELLLLPG 1511



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 59/249 (23%), Positives = 77/249 (30%), Gaps = 55/249 (22%)

Query: 41   LLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVR-PPSTPHL 99
            L P       L         T    P   P  L  P   PL +G + PA  R PP  P L
Sbjct: 1175 LAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEP---PLPVGVEEPADSREPPEEPGL 1231

Query: 100  LSASALSAQLDSPAR---------------------PHPRCYPPFALSAPRPPALGASAT 138
                A+    + PA+                     P P    P  L  P PP       
Sbjct: 1232 SQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPP--- 1288

Query: 139  AFRSSSDPP-------ARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWR 191
              R  S PP       + P +     A       P    S   +Q     P++PG  P  
Sbjct: 1289 --RPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPL 1346

Query: 192  CLSLSVSDLKLPLPPSWPWLGFSAALPA--------------AFRPCSAPPAWPRLLPLA 237
                S   L  P  P  P+  + A  P+              +F P  + P+ P LLP+ 
Sbjct: 1347 SGGSSGLSLSSPQVPGSPF-SYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVC 1405

Query: 238  LAFPVPLGR 246
               P+P GR
Sbjct: 1406 ---PLPTGR 1411



 Score = 36.2 bits (82), Expect = 0.040
 Identities = 62/221 (28%), Positives = 76/221 (34%), Gaps = 40/221 (18%)

Query: 84  GFQGPA--SVRPPST------PHLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGA 135
           GF+GP   S RP ST      P  L  S    +LD    P P   P      P  PA   
Sbjct: 553 GFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEP-----GPPDPAGLL 607

Query: 136 SATAFRS----SSDPPARPRLFRRASASPAQLRL-----PSRLASALSAQLRLPHPSSPG 186
           S TA  +        P   ++     +S   + +     PS  A   SA    P   +PG
Sbjct: 608 SQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPS--APITSADCPKPMVVTPG 665

Query: 187 VLPWRCLSLSVSDLKLPLPPSW-----------PWLGFSAALPAAFRPCSAPPAWPRLLP 235
                  S+    L LP PP +           P  GF    P    P   PPA P +  
Sbjct: 666 AAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTV 725

Query: 236 LALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLS 276
                P P G P  PPP+     P    PP L  V  V +S
Sbjct: 726 PPPPLPAPPGVP--PPPILPPLPP---FPPGLFPVMQVDMS 761



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 65/233 (27%), Positives = 82/233 (35%), Gaps = 30/233 (12%)

Query: 42  LPPGTGSSHLASAPSTGAS-----TSPTRPRL-LPRSLGY--PLRHPLDLGFQGPASV-- 91
           L  G GS   +  P++G +     T+ +  RL  P S G   PL   L   F   +S   
Sbjct: 232 LSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSS 291

Query: 92  RPPSTPHLLSASAL---------SAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRS 142
           R P+  +L S             S   D+  R H   Y     ++P   A+  +  AFR 
Sbjct: 292 RQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHY---VHNSPAVTAVAGATAAFRG 348

Query: 143 SSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLS-LSVSDLK 201
           SSD P         S+ P     P    SA  A    P  ++P        S        
Sbjct: 349 SSDLPFGAVGGTGGSSGPPFKAQPQ--DSATFAHTPPPAQATPAPGFKSAFSPYQTPVAH 406

Query: 202 LPLPPSWP--WLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPP 252
            P PP  P     F A     FR   APP  P   PLA   P   G P  PPP
Sbjct: 407 FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKP---GTPPGPPP 456


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 73/246 (29%), Positives = 89/246 (36%), Gaps = 46/246 (18%)

Query: 43  PPGTGSSHLASAPSTGASTSPTRPRLL--PRSLGYPLRHPLDLGFQGPASVRPPSTPHLL 100
           PP      LA  P   AS   T P L   P     PL+ P       P +  PP TP   
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP-----PSPLTTPPPETP--- 584

Query: 101 SASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASP 160
                     S A P P+  P  AL++P    L +   +  ++  P A P L     A P
Sbjct: 585 ---------SSIATPPPQAPP--ALASPPLQGLPSPPLSPLATPPPQAPPXL-----ALP 628

Query: 161 AQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAA 220
                PS  AS   + L  P P +P  L    L    S      PPS P       + A 
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-----PPSPP-------VQAP 676

Query: 221 FRPCSAPPAWPRLLPLALAFP--------VPLGRPRLPPPVFGSTRPALASPPLLGSVRS 272
           F P ++PP  P   P + A P        VP   P  PP    +T P  A PPL      
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736

Query: 273 VRLSPP 278
           V  SPP
Sbjct: 737 VPPSPP 742



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 75/253 (29%), Positives = 95/253 (37%), Gaps = 50/253 (19%)

Query: 43  PPGTGSSHLASAPSTGAST--------SPTRPR-----LLPRSLGYPLRHPLDLGFQGPA 89
           PP      L + PS  AS         SP  P      LL      P   P+   F  PA
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681

Query: 90  S--VRPPSTPHLLSASALSAQ-------------LDSPARPHPRCYPPFALSAPR---PP 131
           S  V P +TP   +  +L+A              +   A P P+  PP  L+AP    PP
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP--LAAPPLQVPP 739

Query: 132 ALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWR 191
           +  AS     S++ PP  P L    +A P Q+  PS  AS   + L  P P +P  L   
Sbjct: 740 SPPASPPMSPSATPPPRVPPLL---AAPPLQVP-PSPPASLPMSPLAKPPPQAPPALATP 795

Query: 192 CLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPP 251
            L        LP PP+      S    A F P ++ P  P   P   A PV L  P L  
Sbjct: 796 PLQ------ALPSPPA------SFPGQAPFSPSASLPMSPLATPPPQAPPV-LAAPLLQV 842

Query: 252 PVFGSTRPALASP 264
           P      P L +P
Sbjct: 843 PPSPPASPTLQAP 855



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 69/253 (27%), Positives = 94/253 (37%), Gaps = 28/253 (11%)

Query: 38  KFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTP 97
           K + L  G         P T +     R R     +G P   P        A  RPP+  
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP-------SARPRPPTEG 204

Query: 98  HLLSASALSAQLDSPARPHPRCYPPFA--LSAPRPPALGASATAFRSSSDPPARPRLFRR 155
              S S+ S    +   P  R  P     L  P   +L +SAT   S +      R   R
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 156 ASASPAQLRLPSRLASALSAQLRLPHP-SSPGVLPWRCLSL---SVSDLKL-PLPPSWPW 210
           A A P+Q + P  L +    Q+  P   ++P + P     L   S S  K  P+PP    
Sbjct: 265 APAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP--- 320

Query: 211 LGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRL-----PPPVFGSTRPALASPP 265
              +AA P    P + PP+ P   PL LA P P   P L     PP    S  P   + P
Sbjct: 321 --DNAATPL---PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375

Query: 266 LLGSVRSVRLSPP 278
            + +  S++  PP
Sbjct: 376 PMQAPPSLQTIPP 388


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 77/267 (28%), Positives = 94/267 (35%), Gaps = 58/267 (21%)

Query: 41  LLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPL-DLGFQGPASVRPPSTPHL 99
           L PP        +AP+ G  +S             PL  P      Q  A    P+TPH 
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSS------------PLATPSPSAALQSQAPPTLPATPH- 326

Query: 100 LSASALSAQLDSP---ARPHPRCYPPFALSAPRPPALGASATAFRSSS-----------D 145
             +S+L+ QL +P   A P P   PP   + P PPA   S       S            
Sbjct: 327 --SSSLTCQLATPLPLAPPSPSA-PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383

Query: 146 PPARPRLFRRASASPAQLRLP------SRLASALSAQLRLPHPSSPGVLPWRCLSLSVSD 199
           PP  P       A PA L LP      S  AS   + L  P P +P  L    L    S 
Sbjct: 384 PPLSPLATPPPQAPPA-LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 442

Query: 200 LKLPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFP--------VPLGRPRLPP 251
                PPS P       + A F P ++PP  P   P + A P        VP   P  PP
Sbjct: 443 -----PPSPP-------VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 490

Query: 252 PVFGSTRPALASPPLLGSVRSVRLSPP 278
               +T P  A PPL      +   PP
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPP 517



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 78/279 (27%), Positives = 105/279 (37%), Gaps = 42/279 (15%)

Query: 45  GTGSSHLASAPSTGASTSPTRPRLLPR-----SLGYPLRHPLDLGFQGPASV-------R 92
           G  SS   + PS  A+     P  LP      SL   L  PL L    P++         
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356

Query: 93  PPSTPHLLSASALSA---QLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPAR 149
           PP+TP   + ++L +   Q      P P   P        PPAL  +    ++   PPA 
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL--ALPPLQAPPSPPAS 414

Query: 150 PRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWP 209
           P L   A+ SP   + P+ LA  L      P PS P   P+              PP+ P
Sbjct: 415 PPLSPLATPSP---QAPNALAVHLLQAPFSPPPSPPVQAPFS-------------PPASP 458

Query: 210 WLGFSAALPA------AFRPCSAPPAWPRLLPLA-LAFPVPLGRPRLPPPVFGSTRPALA 262
            +  SA  P+      A  P   PP+ P   P++  A P P   P L  P     +P   
Sbjct: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518

Query: 263 SPPLLGSVRSVRLSPPGFSFLRFRRF--SSALSASPHGT 299
           +PP L +     L  P  SF     F  S++L  SP  T
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 557



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 66/233 (28%), Positives = 77/233 (33%), Gaps = 61/233 (26%)

Query: 56  STGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPAS-------VRPPSTPHLLSASALSAQ 108
           S   S S T P   P SL  P   PL +    PAS         PP  P  L+A  L   
Sbjct: 457 SPPVSPSATPPSQAPPSLAAP---PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513

Query: 109 LDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSR 168
              P  P     PP   + P PPA       F  S+  P  P                  
Sbjct: 514 KPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSP------------------ 554

Query: 169 LASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPP 228
                   L  P P +P VL    L +       P PP+ P       L A  RP +  P
Sbjct: 555 --------LATPPPQAPPVLAAPLLQVP------PSPPASP------TLQAPRRPPTPGP 594

Query: 229 ----AWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSP 277
               + PR L LALA       P  PPP   S    L+ P L G   S   +P
Sbjct: 595 DTSVSGPR-LTLALA-------PGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 66/259 (25%), Positives = 94/259 (36%), Gaps = 24/259 (9%)

Query: 38  KFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTP 97
           K + L  G         P T +     R R     +G P   P        A  RPP+  
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP-------SARPRPPTEG 204

Query: 98  HLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARP--RLFRR 155
              S S+ S    +   P  R  P       RP +   S++A   SS   + P  R   R
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 156 ASASPAQLRLPSRLASALSAQLRLPH-PSSPGVLPWRCLSLSV----SDLKLPLPPSWPW 210
           A A P+Q + P  L +    Q+  P   ++P + P     L+     + L+   PP+ P 
Sbjct: 265 APAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323

Query: 211 LGFSAA--------LPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALA 262
              S++        LP A    SAPP+  + LP   A P       L  P   +T   L 
Sbjct: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSL-QTLPSPPATPPSQATTSLGSPTLQATHSFLP 382

Query: 263 SPPLLGSVRSVRLSPPGFS 281
           SPPL         +PP  +
Sbjct: 383 SPPLSPLATPPPQAPPALA 401


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 69/221 (31%), Positives = 86/221 (38%), Gaps = 56/221 (25%)

Query: 88  PASVRPPSTPHLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPP 147
           P  V PPS P  +   AL A +  P  P P   P    S P PP +  S +   S+  PP
Sbjct: 534 PPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVP-PPGMPPSLS---SAGPPP 589

Query: 148 ARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPS 207
             P               P  L+SA            P VLP   LS +     +PLPP 
Sbjct: 590 VLP---------------PPSLSSA----------GPPPVLPPPSLSSTAPPPVMPLPP- 623

Query: 208 WPWLGFSAALPAAFRPCSAPPAWPRLLPLAL-AFPVPLG----------RPR---LPPPV 253
                 S+A P    P   PP  P+ +P  L A PVP            +PR   LP PV
Sbjct: 624 -----LSSATPP---PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPV 675

Query: 254 -FGSTRPALASPPLLGSVRSVRL---SPPGFSFLRFRRFSS 290
            FGS  P    PPL  +  S ++   +P   S L +  FSS
Sbjct: 676 SFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSS 716



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 43/149 (28%), Positives = 55/149 (36%), Gaps = 36/149 (24%)

Query: 66  PRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHPRCYPPFAL 125
           P L+P  L  P   P       P S  PPS  ++            P +P P  YPP + 
Sbjct: 136 PGLVPMELESPPESPP----VPPGSYMPPSQSYM-----------PPPQPPPSYYPPTSS 180

Query: 126 SAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPH---- 181
               PPA  +       S  PP++  L      +P     PS  +S+ S+Q  L H    
Sbjct: 181 QPYLPPAQPS------PSQSPPSQSYL------APT----PSYSSSSSSSQSYLSHSQSY 224

Query: 182 -PSSPGVLPWRCLSLSVSDLKLPLPPSWP 209
            PSS           S S L  P PPS P
Sbjct: 225 LPSSQASPSRPSQGHSKSQLLAPPPPSAP 253



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 8/51 (15%)

Query: 216 ALPAAFRPCSA-PPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPP 265
           ++P  F P S  PP  P +       P P+  P LPPPV     PA   PP
Sbjct: 515 SMPPPFVPYSQMPPPLPTM-------PPPVLPPSLPPPVMPPALPATVPPP 558


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 72/291 (24%), Positives = 106/291 (36%), Gaps = 26/291 (8%)

Query: 4    PISPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAPSTGASTSP 63
            P +P+P + P L    ++  +    R    P  +  +  P G  +   A+ PS     + 
Sbjct: 900  PATPAPKQAPALSMTSSSPKKA---RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956

Query: 64   TRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHPRCYP-P 122
              P+  P         P      GPA+  P   P   +A+  S +   PA P P+  P P
Sbjct: 957  PSPKWAPTPPAATPPSPKG----GPATPSPKGAPTPPAATPPSPK-GGPATPSPKGAPTP 1011

Query: 123  FALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPH- 181
             A++ P P    A+    + +S PPA          SPA   LP    +  +A L  P  
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATP--PSPKGSPAATPLPKGAPTTPAATLPSPKG 1069

Query: 182  ----------PSSPGVLPWRCLS--LSVSDLKLPLPPSW--PWLGFSAALPAAFRPCSAP 227
                      P+ P   P        + S    P+PP+   P      A P      + P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 228  PAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSPP 278
             A P      LA P P G P  P     S +  LA+PP  G+  +   +PP
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 66/240 (27%), Positives = 89/240 (37%), Gaps = 28/240 (11%)

Query: 52   ASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDS 111
            A  PS     SP    L P+    P    L    +GPA+  P   P L   S  S+   +
Sbjct: 864  APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS--SSPKKA 921

Query: 112  PARPHPRCYP--PFALSAPRPPAL------GASATAFR--SSSDPPARPRLFRRASASPA 161
             A P P+  P  P    AP PPA       G  AT     + + P A P   +   A+P+
Sbjct: 922  RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981

Query: 162  QLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALP--- 218
                P+  A+   +    P   SP   P      +   +  P P   P     AA P   
Sbjct: 982  PKGAPTPPAATPPSPKGGPATPSPKGAP------TPPAVTPPSPKGSP-----AATPFPK 1030

Query: 219  AAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSPP 278
             A  P +A P  P+  P A   P+P G P  P     S +   A+P L G+      +PP
Sbjct: 1031 GASTPPAATPPSPKGSPAAT--PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 76/282 (26%), Positives = 98/282 (34%), Gaps = 48/282 (17%)

Query: 43   PPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQG-PASVRP-----PST 96
            PP    S  A+    GAST P      P+  G P   PL  G    PA+  P     P+T
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPK--GSPAATPLPKGAPTTPAATLPSPKGGPAT 1073

Query: 97   PHLLSASALSAQLD-----SPARPHPRCYP-PFALSAPRPPALGASATAFRSSSDPPARP 150
            P L  A    A         PA P P+  P P A + P P    A+     + + P A P
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133

Query: 151  RLFRRASASPAQLRLPSRLASALSAQ---LRLPHPSSPGVLPWRCLSLSVSDLKLPLP-- 205
               +   A+P     P+  A+   +    L  P P      P          L  P P  
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG 1193

Query: 206  --------PSWPWLGFSAALP--AAFRPCSAPPA--------WPRLLPLALAF--PVPLG 245
                    P  P  G +   P  A   P + PP+         P+  P   A   P P G
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253

Query: 246  RPRLPPPVFGSTRPA---------LASPPLLGSVRSVRLSPP 278
             P  PPP    T PA         LA+PP  G+     ++PP
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 66/251 (26%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 43   PPGTGSSHLASAPST--GAST-----SPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPS 95
            P G  ++  A+ PS   G +T     +PT P   P SL   L  P   G   PA V PPS
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296

Query: 96   --------------TPHLLSASALSAQLDSPARPHPRCYP-PFALSAPRP---PALGASA 137
                          TP    A+   +   SP  P P+  P P A++ P P   P L A+ 
Sbjct: 1297 PKGGPATSPPKGAPTP---PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353

Query: 138  TAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLP----HPSSPGVLPWRCL 193
             + +     P+        +A+P+    P+    +      +P     P+SP V+P    
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP---- 1409

Query: 194  SLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPV 253
                  L     P+ P     AA P+     + P   P  L  A A   P G P  P   
Sbjct: 1410 ------LSPKKAPATPVTREGAATPSK-GDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462

Query: 254  FGSTRPALASP 264
               T PA+  P
Sbjct: 1463 GDPTLPAVTPP 1473



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 61/226 (26%), Positives = 74/226 (32%), Gaps = 35/226 (15%)

Query: 44   PGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSAS 103
            P +    LA+ P  GA   PT P   P S    L  P   G     +  PPS    L+  
Sbjct: 1156 PPSPKGGLATPPPKGA---PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212

Query: 104  ALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQL 163
            +      +PA   P   P   L+ P P   GA  T   +   P   P       A     
Sbjct: 1213 SPKGAPTTPAATPPS--PKGGLATPSPK--GAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268

Query: 164  RLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRP 223
              P  L   L+     PH  +P                +  PPS P  G     PA   P
Sbjct: 1269 ATPPSLKGGLATP---PHKGAPNPA-------------VVTPPS-PKGG-----PATSPP 1306

Query: 224  CSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGS 269
              AP       P A   P P G P  PPP    T PA+  P   G+
Sbjct: 1307 KGAPT------PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT 1346



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 64/244 (26%), Positives = 86/244 (35%), Gaps = 35/244 (14%)

Query: 38   KFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTP 97
            K +L PP      L  AP+T A   P      P S G P      L    P S + P  P
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSA---PKGGPATPSSKGDPT-----LPAVTPPSPKEPPAP 1481

Query: 98   HLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRAS 157
              ++ S  S+   +PA P P   P      P  P       A  SS   P  P     + 
Sbjct: 1482 KQVATS--SSPKKAPATPAPMGAPTLPAVIPSSPK---EVPATPSSRRDPIAPTATLLSK 1536

Query: 158  ASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAAL 217
             +PA L     L   +   + +P P     +P        +  + P  PS       A+ 
Sbjct: 1537 KTPATLAPKEAL---IPPAMTVPSPKKTPAIP--------TPKEAPATPS----SKEASS 1581

Query: 218  PAAFRPCS---APPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVR 274
            P A  P +   AP     L+P A+  P P   P  PP V   T P+    P   + +   
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP-TPPAV---TPPSPEKGPATPAPKGTP 1637

Query: 275  LSPP 278
             SPP
Sbjct: 1638 TSPP 1641



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 65/245 (26%), Positives = 91/245 (37%), Gaps = 54/245 (22%)

Query: 43   PPGTGSSHLASAPSTGASTS-----------PTRPRLLPRSLGYPLRHPLD-LGFQGPAS 90
            PP    SH      T  S             PT P ++P S   P + P   +  +G A+
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS---PKKAPATPVTREGAAT 1427

Query: 91   -----VRPPS-TP-HLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSS 143
                 + PP+ TP  L  A A SA    PA P  +  P      P  P    +     +S
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487

Query: 144  SDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLP 203
            S P       ++A A+PA +  P+  A           PSSP  +P      + S  + P
Sbjct: 1488 SSP-------KKAPATPAPMGAPTLPAVI---------PSSPKEVP-----ATPSSRRDP 1526

Query: 204  LPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPA--- 260
            + P+   L  S   PA   P  A      L+P A+  P P   P +P P      P+   
Sbjct: 1527 IAPTATLL--SKKTPATLAPKEA------LIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578

Query: 261  LASPP 265
             +SPP
Sbjct: 1579 ASSPP 1583



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 47/199 (23%), Positives = 66/199 (33%), Gaps = 25/199 (12%)

Query: 4    PISPSPSKFPVL--------QEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAP 55
            P +P+P   P L        +E+ AT      +R    P     +   P T +   A  P
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSS---RRDPIAPTATLLSKKTPATLAPKEALIP 1550

Query: 56   STGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRP------PSTPHLLSASALSAQL 109
                  SP +   +P     P   P       P +V P      PS   LL   A+++  
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPAT-PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609

Query: 110  DSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRL 169
               A   P   PP     P  PA   + T+      PP  P   + +  SPA +      
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTPTS------PPVTPSSLKDSPTSPASVTCKMG- 1662

Query: 170  ASALSAQLRLPHPSSPGVL 188
            A+   A   LP    P  L
Sbjct: 1663 ATVPQASKGLPAKKGPTAL 1681



 Score = 28.5 bits (62), Expect = 8.3
 Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 10/110 (9%)

Query: 165 LPSRLASALSAQLRLPHPSSP---GVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAF 221
           LP   A +++A L  P P+ P      P +C  LS ++   P P   P    S  L   F
Sbjct: 26  LPMSSALSVTAALGQPGPTLPPPCSPAPQQC-PLSAANQASPFPS--PSTIASTPLEVPF 82

Query: 222 RPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVR 271
              S+  A    LPL  A   P   P L  P       ALASP +  +++
Sbjct: 83  PQSSSGTA----LPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128



 Score = 28.5 bits (62), Expect = 8.3
 Identities = 38/154 (24%), Positives = 56/154 (36%), Gaps = 22/154 (14%)

Query: 4   PISPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAPSTGASTSP 63
           P SP+P + P+     A+           FP        P        +S  +    T+P
Sbjct: 48  PCSPAPQQCPLSAANQASP----------FPSPSTIASTPLEVPFPQSSSGTALPLGTAP 97

Query: 64  TRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPA-RPH----PR 118
             P  LP  +G P+  P  L     A   P   P L    + SA L   A  PH      
Sbjct: 98  EAPTFLPNLIGPPI-SPAAL-----ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSS 151

Query: 119 CYPPFALSAPRPPALGASATAFRSSSD-PPARPR 151
            +PP  L++P   A+  S +    S+   P+ P+
Sbjct: 152 AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 98/350 (28%), Positives = 126/350 (36%), Gaps = 77/350 (22%)

Query: 6   SPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAPSTGASTSPT- 64
           SP+P   P +  ++A +Y         +   ++ +L+P   GS     A S+  S  P  
Sbjct: 211 SPAPPPPPAIS-LNAPSYN--------WGAALRSSLVPSDLGSPPAPHASSSPPSDPPLF 261

Query: 65  ------RPRLLPRSLGYP---------------LRHPLDLGFQGPA-SVRPPSTPHLLSA 102
                  P  LP S   P               +  PL LG  G A +V  P  P  L++
Sbjct: 262 HCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLAS 321

Query: 103 SALSAQLDSPARPHPRCYPPFALSAPRPPALGASA---TAFRSSSDPPAR-PRLFR---- 154
           S LSA   +    HP   PP  L   RP A   SA   ++ R S   P R P +FR    
Sbjct: 322 SLLSAAAKAQ---HPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEG 378

Query: 155 RASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPP----SWPW 210
           R   +P + R   R  + +     LP PS P +LP     LS+  L  P P     S+  
Sbjct: 379 RGPQTPRRSR--PRAPAPVPQPFSLPEPSQP-ILP---SVLSLLGLPTPGPSHSDGSFNL 432

Query: 211 LGFSAALPAAFRPCSAPPAWPR----------------LLPLALAFPVPLGRPRLPPPVF 254
           LG  A LP      S  P  PR                 +P A A P     P +P PV 
Sbjct: 433 LGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVL 492

Query: 255 GS--------TRPALASPPLLGSVRSVRLSPPGFSFLRFRRFSSALSASP 296
            S          PA   PPL G       SP     L    F   L A P
Sbjct: 493 QSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALP 542



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 72/272 (26%), Positives = 94/272 (34%), Gaps = 43/272 (15%)

Query: 44  PGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPST------- 96
           PGT S  L+S P   A  + ++  ++P  +       L +G  GPA   PP         
Sbjct: 462 PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMG-AGPACPLPPLAGGEAFPF 520

Query: 97  PHLLSASALS-AQLDSPARPHPRCYPPFALSAPRP-PALGASATAFRSSS--DPPARPRL 152
           P      ALS A         P    P +L  P P P L  S     +     PP  P L
Sbjct: 521 PSPEQGLALSGAGFPGMLGALPL---PLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLL 577

Query: 153 FRRASA----SPAQLRLPSRLASAL---SAQLRLPHPSSP------GVLPWRCLSLSVSD 199
                     +P +   PS L ++L        LP PS+P        LP   L  +  D
Sbjct: 578 PPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGD 637

Query: 200 LKLPL-----PPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVF 254
            +        P   P+ G     P  F P SAPP    L    LA         L PP  
Sbjct: 638 GEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLA-------ATLDPPSG 690

Query: 255 GSTRPALASPPLLG---SVRSVRLSPPGFSFL 283
              +P + S P  G   S  +   + PG S L
Sbjct: 691 TPPQPCVLSAPQPGPPTSSVTTATTDPGASSL 722



 Score = 32.3 bits (72), Expect = 0.57
 Identities = 44/162 (27%), Positives = 56/162 (34%), Gaps = 38/162 (23%)

Query: 138 TAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSV 197
           T   SS    A P++F   S  P   R P R+          P    PG LP        
Sbjct: 120 TCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTT------PLNGGPGSLP-------- 165

Query: 198 SDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGST 257
                P PPS      S A P    P         L P  LA PVP G    P  +    
Sbjct: 166 -----PEPPS-----VSQAFPTLAGPGG-------LFPPRLADPVPSGGSSSPRFLPRGN 208

Query: 258 RPALASPPLLGSVRSVRLSPPGFSF---LRFRRFSSALSASP 296
            P+ A PP      ++ L+ P +++   LR     S L + P
Sbjct: 209 APSPAPPP----PPAISLNAPSYNWGAALRSSLVPSDLGSPP 246


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 63/211 (29%), Positives = 83/211 (39%), Gaps = 30/211 (14%)

Query: 80  PLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHPRCYP-PFALSAPRP-PALGASA 137
           P D+ F         +    +S    S +L S A P P   P P    AP P PAL ++A
Sbjct: 470 PGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAA 529

Query: 138 TAFRSSSDPPARPRLFRRASASPAQLRLPSRLASA---LSAQLRLPHPSSPGVLPWRCLS 194
           T  R+ S+ P RP       ASP   R P   A+    ++ + + P P+ P + P +   
Sbjct: 530 TKERTESEVPPRP-------ASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSG 582

Query: 195 LSVSDLKLPLPPSWPWLGFSAALP-----AAFRPCSAPPAWPRLLPLALAFPVPLGR--- 246
              S    PLPP     G   ALP     ++ R  + PP      PL    P P  R   
Sbjct: 583 SRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPP------PLPPTPPQPARRQSR 636

Query: 247 --PRLPPPVFGSTRPALASPPLLGSVRSVRL 275
             P  P P   S  PA  SP  L +   V L
Sbjct: 637 RSPASPSP--ASPGPASPSPVSLSNPAQVDL 665



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 38/119 (31%), Positives = 45/119 (37%), Gaps = 15/119 (12%)

Query: 42  LPPGTGSSHLASAPSTG---ASTSPTRPRLLPRSL-GYPLRHPLDLGFQGPASVRPPSTP 97
           +PP   S   +S P+      S SP  P+ LPR L G  LR P       P  + P    
Sbjct: 575 MPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTV-----PPPLPPTPPQ 629

Query: 98  HLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASAT------AFRSSSDPPARP 150
                S  S    SPA P P    P +LS P    LGA+        A      PPA P
Sbjct: 630 PARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIP 688


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 72/257 (28%), Positives = 83/257 (32%), Gaps = 58/257 (22%)

Query: 44  PGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGP--ASVRPPSTPHLLS 101
           P    S  AS+PS   S     P   P    YP+ +    G  GP  +SV  PS P    
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPP--PAEFSYPVDNQRGSGLAGPKRSSVVSPSHP---- 300

Query: 102 ASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPA 161
               +  L SP  P P   PP A   P PP +G           PP  P +   +  +P 
Sbjct: 301 --PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGI----------PPPPPPVGFGSPGTP- 347

Query: 162 QLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAF 221
                             P PS P   P         D   P PP  P        PAA 
Sbjct: 348 ------------------PPPSPPSFPPH-------PDFAAPPPPPPP--------PAAD 374

Query: 222 RPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLSPPGFS 281
            P   PP   +    A   P P   P  PPP F       A PP L      + S P  S
Sbjct: 375 YPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVS 434

Query: 282 FLRFRRFSSALSASPHG 298
             R    S  LSA   G
Sbjct: 435 DAR----SDLLSAIRQG 447


>gi|169207534 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 183

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 66/198 (33%), Positives = 80/198 (40%), Gaps = 41/198 (20%)

Query: 52  ASAPSTGASTSPTRPRLL--PRSLGYPLRHPLDLGFQGPASVR-PPSTPHLLSASALSAQ 108
           A+ P   A  SP RPR L  PR  G P    L     GP + R PP  P  L  S   A 
Sbjct: 13  AAWPEEKADLSP-RPRFLATPRVPGTPTSQ-LPPRIPGPPTTRQPPRVPDHLHLSCPRA- 69

Query: 109 LDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSR 168
             SP RP P C  P A    R PA+  ++         P RPR    A   P   R P R
Sbjct: 70  --SPDRPRPSC--PLASPDRRRPAIPRAS---------PDRPRPISPAPPGPPTSRQPPR 116

Query: 169 LASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPL----------PPSWPWLGFSAALP 218
           +  +++A   LP P  P   P +   + V+   LPL           P+  WLG +A   
Sbjct: 117 I--SVAAAPVLPAPPRP---PTQRRCVPVAQRGLPLCGTGLGLETRRPARSWLGEAA--- 168

Query: 219 AAFRPCSAPPAWPRLLPL 236
           AAFR     P W    PL
Sbjct: 169 AAFR----FPRWVERFPL 182


>gi|117938768 GNAS complex locus alex [Homo sapiens]
          Length = 626

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 76/289 (26%), Positives = 102/289 (35%), Gaps = 34/289 (11%)

Query: 3   IPISPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGT-----GSSHLASAPST 57
           +P SP PS    L   +ATA  L   R+ C    ++ +L   GT     G   L+   + 
Sbjct: 136 LPRSPKPSGLQRLAPEEATALPL---RRLCHLSLMEKDL---GTTAHPRGFPELSHKSTA 189

Query: 58  GASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHP 117
            AS+  +RPR+  RS   P R  L  G Q P++  P     LL  S  +A       P  
Sbjct: 190 AASSRQSRPRV--RSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRS 247

Query: 118 RCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQ- 176
           R   P   S   P    A  +   +       P++       P   R   R    L  + 
Sbjct: 248 RLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRR 307

Query: 177 -----LRLPHPSSPGV-----LPWRCLSLSV-----SDLKLPLPPSWPWL---GFSAALP 218
                LR   P  PG      LP + L            K+P P     +   G S  +P
Sbjct: 308 EEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIP 367

Query: 219 AAFRPCSAPPAWPRLLPLALAFPVPL-GRPRLPPPVFGSTRPALASPPL 266
              +P    P      PL    P+P  GRP  P P+    RP    PPL
Sbjct: 368 TPGQPLPPQPIPTPGRPLTPQ-PIPTPGRPLTPQPIQMPGRPLRLPPPL 415


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 68/257 (26%), Positives = 104/257 (40%), Gaps = 24/257 (9%)

Query: 39  FNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYP-LRHPLDLGFQGPASVRPPSTP 97
           F L   GTG     + P    + SP    + P + G   + H +   FQ P SV P   P
Sbjct: 174 FILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSV-PAPVP 232

Query: 98  H-----LLSASALSAQLDSPARPHPRCYP-----PFALSAPRPPALGASATAFRSSSDPP 147
           H     +  A+++ A    P  P P   P     P  +S   P ++ AS      +S PP
Sbjct: 233 HSGLVPVQVATSVPAP-SPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPP 291

Query: 148 ARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPS 207
           + P     ++ +PA L +P         Q  +P PS+P ++     +  ++ +    PP+
Sbjct: 292 SGP--VPLSAPAPAPLSVPVSAPPLALIQAPVP-PSAPTLVLAPVPTPVLAPMPASTPPA 348

Query: 208 WPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPR-----LPPPVFGSTRPAL- 261
            P    S  +P    P S PP+ P L+P     PVP   P       P P+  +T  A+ 
Sbjct: 349 AP-APPSVPMPTP-TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIP 406

Query: 262 ASPPLLGSVRSVRLSPP 278
            S P+  S    R+  P
Sbjct: 407 TSAPIPASFSLSRVCFP 423


>gi|130502140 NEZHA isoform 2 [Homo sapiens]
          Length = 1249

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 72/253 (28%), Positives = 96/253 (37%), Gaps = 28/253 (11%)

Query: 34  PGFVKFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRP 93
           P FV+   LP G    H AS   T AS  P +      S  +  RHPL L   GP S   
Sbjct: 319 PDFVQVKDLPDG----HAASPRGTEAS--PPQNNSGSSSPVFTFRHPL-LSSGGPQSPLR 371

Query: 94  PSTPHLLSASALS----------AQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSS 143
            ST  L S+ ++S           QL  P         PF L +     +G        S
Sbjct: 372 GSTGSLKSSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVS 431

Query: 144 SDP--PARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCL--SLSVSD 199
           SD   P RP   R  +  P +   P  L +   A L++ H + P +LP      S  +  
Sbjct: 432 SDSLGPPRPAPARTPTQPPPE---PGDLPTIEEA-LQIIHSAEPRLLPDGAADGSFYLHS 487

Query: 200 LKLPLPPSW--PWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPP-PVFGS 256
            + P  PS   P+L    + P + RP  AP   P     +   P  +G    PP P  GS
Sbjct: 488 PEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGS 547

Query: 257 TRPALASPPLLGS 269
            +   +SP    S
Sbjct: 548 PKAVASSPAATNS 560


>gi|122937255 NEZHA isoform 1 [Homo sapiens]
          Length = 1276

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 72/253 (28%), Positives = 96/253 (37%), Gaps = 28/253 (11%)

Query: 34  PGFVKFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRP 93
           P FV+   LP G    H AS   T AS  P +      S  +  RHPL L   GP S   
Sbjct: 346 PDFVQVKDLPDG----HAASPRGTEAS--PPQNNSGSSSPVFTFRHPL-LSSGGPQSPLR 398

Query: 94  PSTPHLLSASALS----------AQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSS 143
            ST  L S+ ++S           QL  P         PF L +     +G        S
Sbjct: 399 GSTGSLKSSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVS 458

Query: 144 SDP--PARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCL--SLSVSD 199
           SD   P RP   R  +  P +   P  L +   A L++ H + P +LP      S  +  
Sbjct: 459 SDSLGPPRPAPARTPTQPPPE---PGDLPTIEEA-LQIIHSAEPRLLPDGAADGSFYLHS 514

Query: 200 LKLPLPPSW--PWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPP-PVFGS 256
            + P  PS   P+L    + P + RP  AP   P     +   P  +G    PP P  GS
Sbjct: 515 PEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGS 574

Query: 257 TRPALASPPLLGS 269
            +   +SP    S
Sbjct: 575 PKAVASSPAATNS 587


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 47/146 (32%), Positives = 61/146 (41%), Gaps = 27/146 (18%)

Query: 45   GTGSSH-------LASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTP 97
            GTGS          A+ P      + TR R+ PR +G  LR P+ +  Q PAS    + P
Sbjct: 1126 GTGSEEDTPASEPAAALPRKSGRAAATRSRI-PRPIG--LRMPMPVAAQQPASRSHGAAP 1182

Query: 98   HLLSASALSAQLDSP------ARPHPRCYPPFALS-----------APRPPALGASATAF 140
             L +A     QL +P      A   P+  P   L            APR P L AS +A 
Sbjct: 1183 ALDTAITSRLQLQTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAA 1242

Query: 141  RSSSDPPARPRLFRRASASPAQLRLP 166
            R++S  P    L RR S SP+    P
Sbjct: 1243 RNASASPRSQSLSRRESPSPSHQARP 1268


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 43/142 (30%), Positives = 63/142 (44%), Gaps = 12/142 (8%)

Query: 6   SPSPSKFPVLQEIDATAYRLWWQRKFCFPGFVKFNLLPPGTGSSHLASAPSTGASTSPTR 65
           SPSPS+ P     D + + L    K   P   K     PG  +   A  PS   S SPT 
Sbjct: 629 SPSPSQPPA----DQSPHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQPSP-VSLSPTP 683

Query: 66  PRL-LPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPHPRCYPPFA 124
           P    P  L YP  + L  G   PA+  P ++P + +++       S +RP P+      
Sbjct: 684 PSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTL------SKSRPTPKPRQRPT 737

Query: 125 LSAPRPPALGASATAFRSSSDP 146
           L  P+PP +  SA++ +S+  P
Sbjct: 738 LPPPQPPTVNLSASSPQSTEAP 759



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 66/232 (28%), Positives = 86/232 (37%), Gaps = 36/232 (15%)

Query: 43  PPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSA 102
           PP   ++ L S        SP  P L P  LG            GP      ST      
Sbjct: 548 PPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQ---------PGPERT---STTKSKEL 595

Query: 103 SALSAQLDSPARPHPRCYPPFALSAPRPPAL-GASATAFRSSSDPPA--RPRLFRRASA- 158
           S  SAQ  SP           A +  +P A  GA   A  S S PPA   P   R+ S  
Sbjct: 596 SPGSAQKGSPGSSQGT-----ACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKK 650

Query: 159 -SPAQLRLPSRLASALSAQLR-LPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAA 216
            +P   ++P     A++ Q    P P S        LS +      P   S+P  G+S A
Sbjct: 651 LAPIPPKVPFGQPGAMADQSAGQPSPVS--------LSPTPPSTPSPYGLSYPQ-GYSLA 701

Query: 217 L----PAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASP 264
                PAA  P ++P  +   L  +   P P  RP LPPP   +   + +SP
Sbjct: 702 SGQLSPAAAPPLASPSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLSASSP 753


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 74/231 (32%), Positives = 96/231 (41%), Gaps = 43/231 (18%)

Query: 51   LASAPSTGASTSPTRPRLL-PRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQL 109
            LA+APS  +S +P  P LL P S   P  +         ++V P  +P L+ ASAL++  
Sbjct: 1509 LATAPSLSSSQTPGHPLLLAPTSSHVPGLN---------STVAPACSPVLVPASALASPF 1559

Query: 110  DSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRL 169
             S   P P      +L AP   A  A AT       P A P+    A  SPA    P  +
Sbjct: 1560 PSAPNPAP---AQASLLAPASSASQALATPLA----PMAAPQTAILA-PSPAPPLAPLPV 1611

Query: 170  ASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPA-AFRPCSAPP 228
             +            SPG  P   L+ S + + +  P S P    ++A P  A  P  AP 
Sbjct: 1612 LA-----------PSPGAAP--VLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS 1658

Query: 229  AWPRLLPLALAFPVPLGRPRLPPPVFGST---RPALASPPLLGSVRSVRLS 276
            +   +LP     PVP     LP P    T    PALA P L GS  S  LS
Sbjct: 1659 STQTMLPA----PVP---SPLPSPASTQTLALAPALA-PTLGGSSPSQTLS 1701



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 49/174 (28%), Positives = 72/174 (41%), Gaps = 25/174 (14%)

Query: 61   TSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQL---DSPA-RPH 116
            T  + P  +P  +  P+  P+ +    P ++ P    H+L +    +Q+    SPA  P 
Sbjct: 2446 TPASAPAAIPALVPVPVSAPVPISAPNPITILPV---HILPSPPPPSQIPPCSSPACTPP 2502

Query: 117  PRCYPPFALSAPR---------------PPALGASATAFRSSSDPPARPRLFRRASASPA 161
            P C PP A + P                PP++  SA+             L  +A ASP 
Sbjct: 2503 PACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPE 2562

Query: 162  QLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSA 215
             L L S +AS+ ++ L L  P    +LP     L VS+  L L PS P L   A
Sbjct: 2563 SLELAS-VASSETSSLSLVPPKD--LLPVAVEILPVSEKNLSLTPSAPSLTLEA 2613



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 4/47 (8%)

Query: 223  PCSAPPAWPRLLPLALAFPVPLGRPR----LPPPVFGSTRPALASPP 265
            P SAP A P L+P+ ++ PVP+  P     LP  +  S  P    PP
Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPP 2493



 Score = 31.6 bits (70), Expect = 0.98
 Identities = 50/177 (28%), Positives = 57/177 (32%), Gaps = 43/177 (24%)

Query: 87   GPASVRPPSTPHLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDP 146
            GP  VRPP  P L             A+P P          P P  L AS     S + P
Sbjct: 1020 GPVPVRPPPGPEL------------SAQPTP---------GPVPQVLPASLMVSASPAGP 1058

Query: 147  PARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPP 206
            P  P     AS  P  + LP    ++ S    LP P   GVL                 P
Sbjct: 1059 PLIP-----ASRPPGPVLLPPLQPNSGSLPQVLPSPL--GVLSGTS------------RP 1099

Query: 207  SWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALAS 263
              P L      PA  R   APP  P    L     VP G    PP    +T    A+
Sbjct: 1100 PTPTLSLKPTPPAPVRLSPAPP--PGSSSLLKPLTVPPGY-TFPPAAATTTSTTTAT 1153



 Score = 28.9 bits (63), Expect = 6.3
 Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 24/164 (14%)

Query: 45   GTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASA 104
            G   + + SA  T ++T+P  PR  P     P   P           RP  TP       
Sbjct: 2408 GANHTPVISAHQTRSTTTP--PRCSPARERVPRPAP-----------RPRPTP------- 2447

Query: 105  LSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLR 164
             SA    PA        P  +SAP P  +         S  PP++       + +P    
Sbjct: 2448 ASAPAAIPALVPVPVSAPVPISAPNPITI--LPVHILPSPPPPSQIPPCSSPACTPPPAC 2505

Query: 165  LPSRLASALSAQLRLPHPSSPGVL--PWRCLSLSVSDLKLPLPP 206
             P    +   AQ  L  PSSP +L  P   +S SV++L L L P
Sbjct: 2506 TPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRP 2549


>gi|71274152 hypothetical protein LOC388939 [Homo sapiens]
          Length = 1288

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 60/256 (23%), Positives = 91/256 (35%), Gaps = 30/256 (11%)

Query: 48   SSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSA 107
            SS+  + PS  A  +P  P + PR L  P           P    PP       ++    
Sbjct: 1014 SSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPP-----ESAPAQC 1068

Query: 108  QLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPS 167
            ++ SP   HP   PPF++ +P PP   + +   + + D      +  + S +   +  P+
Sbjct: 1069 KVPSPPTQHPEASPPFSIPSPSPPM--SPSQEHKETRDSEDSQAVIAKVSGNTHSIFCPA 1126

Query: 168  RLASALSAQ--LRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAF---- 221
              +S   A+  L   HP +P  LP        +  +     S PWL   +   AA     
Sbjct: 1127 -TSSLFEAKPPLSTAHPLTPPSLPPEAGGPLGNPAECWKNSSGPWLRADSQRRAALCALN 1185

Query: 222  -----------RPCSAPPAWPRLLPLALAFPVPLGR---PRLPPPVFGSTRPALASPPLL 267
                       R     P  P L P + ++   LG+       P        +  SP L 
Sbjct: 1186 PLPFLRRTASDRQPGGRPQPPTLDPTSTSYESQLGQNSSSEESPKKDTEPGSSPCSPELQ 1245

Query: 268  GSVRSVRLSPPGFSFL 283
            G  R  R SPP F  L
Sbjct: 1246 GGTR--RASPPEFCVL 1259


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 59/206 (28%), Positives = 84/206 (40%), Gaps = 44/206 (21%)

Query: 44   PGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSAS 103
            P  GS H     S G + S +R R  P  +  P+RH                 P +L +S
Sbjct: 2314 PSGGSGHSGGPSSCGGAPSTSRSR--PSRIPQPVRHH----------------PPVLVSS 2355

Query: 104  ALSAQLDS----------PARPHPRCYPPFALSAP--RPPALGASATAFRSSSDPPARPR 151
            A S+Q ++          P+ P P   P    SAP  RPP  GA A      ++P  + +
Sbjct: 2356 AASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPP--GADAEGSEREAEPIPKMK 2413

Query: 152  LFR-----RASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRC-LSLSVSDL-KLPL 204
            +        A+AS +    P++ A A    L L  P +    P    LS +V  L K P 
Sbjct: 2414 VLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPF 2473

Query: 205  PPSWPWL---GFSAALPAAFRPCSAP 227
            PPS P      F +++PA+  P S P
Sbjct: 2474 PPSSPLQKGGSFWSSIPAS--PASRP 2497


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 72/264 (27%), Positives = 95/264 (35%), Gaps = 46/264 (17%)

Query: 45  GTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPL---DLGF----QGPAS------- 90
           GT      SA + GAST PT   L     G+P+  P    D+      QGP S       
Sbjct: 78  GTNKEGGGSANTRGASTPPTLGDLFAG--GFPVLRPAGQRDVAGGKTGQGPGSRAPSPRL 135

Query: 91  --------VRPPSTPHLLSAS-ALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFR 141
                   + PP++P L + S A  A   +P RP+    PP     P PP          
Sbjct: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP-----PTPPPPPPPLPPPL 190

Query: 142 SSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPW------RCLSL 195
            SS P   P +      +   L + +            P P +P  LP       + +  
Sbjct: 191 PSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKP 250

Query: 196 SVSDLKLP-LPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVF 254
            ++ L LP +PP  P L      P  +    A PA     P   A   P   P LPP   
Sbjct: 251 QLAPLHLPPIPPPLPLLP-----PCGYPGLKAEPA----SPAQDAQEPPAPPPPLPPYAS 301

Query: 255 GSTRPALASPPLLGSVRSVRLSPP 278
            S R +L +PPL G   S    PP
Sbjct: 302 CSPRASLPAPPLPGVNSSSETPPP 325



 Score = 35.0 bits (79), Expect = 0.088
 Identities = 63/235 (26%), Positives = 78/235 (33%), Gaps = 34/235 (14%)

Query: 41  LLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLL 100
           L+PP +      S     A T+P RP +       P   P       P    PP  P L 
Sbjct: 144 LIPPASPRLGNTSEAHGAARTAPPRPNV-------PAPPP-----PTPPPPPPPLPPPLP 191

Query: 101 SASALSAQLDSPARPH-----PRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRR 155
           S+S +   L SP  P      P   PP   + P PP            + PP  P     
Sbjct: 192 SSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP-------TPPPLPPASVLS 244

Query: 156 ASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCL-SLSVSDLKLPLPPSWPWLGFS 214
             A   QL  P  L         LP    PG+       +    +   P PP  P+   S
Sbjct: 245 DKAVKPQLA-PLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCS 303

Query: 215 --AALPAAFRP-----CSAPPAWPRLLPLALAFPVPLGRPRLP-PPVFGSTRPAL 261
             A+LPA   P        PP  P   P   A P   G   LP PP    ++P L
Sbjct: 304 PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFL 358


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 70/278 (25%), Positives = 103/278 (37%), Gaps = 47/278 (16%)

Query: 34   PGFVKFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRP 93
            P F K          S  +  P   A   P+    +P S   PL          PA++ P
Sbjct: 1727 PRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPL----------PATLTP 1776

Query: 94   --PSTPHLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPR 151
               ST   + AS L+  L S + P            P  P    SA+A  S+S P +   
Sbjct: 1777 VPASTSAPVPASTLAPVLASTSAP-----------VPASPLAPVSASASVSASVPASTSA 1825

Query: 152  LFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWL 211
                +S++PA    P+ + +++S       P+S  +L    + +  S L     P+    
Sbjct: 1826 AAITSSSAPASAPAPTPILASVST------PASVTILASASIPILASALASTSAPTPAPA 1879

Query: 212  GFSAALP---AAFRPCSAPPAWPRLLPLALA----FPVPLGRPRLPPPVFGSTRPALASP 264
              S A P   A   P SAP A   L P + +     P P+  P   PP    T+     P
Sbjct: 1880 ASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKP 1939

Query: 265  ---PLLGSVRSVRLSPPGFSFLRFRRFSSALSASPHGT 299
               PL  + +S +  PP        R  SA   +P+GT
Sbjct: 1940 VQNPLQTTSQSSKQPPPSI------RLPSA--QTPNGT 1969


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 43/144 (29%), Positives = 58/144 (40%), Gaps = 35/144 (24%)

Query: 128  PRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGV 187
            P+P ALG        S  P A P +F  +  +PA L      +++    L+ P  S PG 
Sbjct: 2108 PQPGALG--------SPPPAAAPTIFIGSPTTPAGL------STSADGFLKPPAGSVPG- 2152

Query: 188  LPWRCLSLSVSDLKLPLPPSWPW-------LGFSAALPAAFRPCSAPPAWPRLLPLALAF 240
                    S  +L L LPP  P         G + A P   R  +APP +P        +
Sbjct: 2153 ------PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYP-------PY 2199

Query: 241  PVPLGRPRLPPPVFGSTRPALASP 264
            P P G P  PP +  S+RP    P
Sbjct: 2200 PSPTGAPAQPPMLGASSRPGAGQP 2223



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 68/242 (28%), Positives = 78/242 (32%), Gaps = 48/242 (19%)

Query: 42  LPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLS 101
           L P    S L+  P +    SP  P L    L  P   P     + P S  P ++P  LS
Sbjct: 494 LSPPPEESPLSPPPES----SPFSP-LEESPLSPPEESPPSPALETPLSPPPEASP--LS 546

Query: 102 ASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSS--SDPPARPRLFRRASAS 159
                + L  P    P   PP A     PP     +     S  S PP   RLF     S
Sbjct: 547 PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES 606

Query: 160 PAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPA 219
           P                L  P   SP   P     LS      P+ P           P 
Sbjct: 607 P----------------LSPPPEESPLSPPPEASRLSPPPEDSPMSP-----------PP 639

Query: 220 AFRPCSAPPAWPRLLPLALAF---PVPLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLS 276
              P S PP   RL PL +     P P   P  PPP    T P    PP      + RLS
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP----PP-----EASRLS 690

Query: 277 PP 278
           PP
Sbjct: 691 PP 692



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 69/267 (25%), Positives = 96/267 (35%), Gaps = 49/267 (18%)

Query: 35   GFVKFNLLPPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPP 94
            GFV         G   L +     A  +P   ++ P+S G  LR P +       +  PP
Sbjct: 2305 GFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLR-PQEPPPAQALAPSPP 2363

Query: 95   STPHLLS-ASALSAQLDSPARPHPRCYPPFALSAPRPPALGA-------SATAFRSSSDP 146
            S P +    S        P  P P+  PP +  A  P +L +       ++   +SSS  
Sbjct: 2364 SHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQS 2423

Query: 147  PARPRLFRRASASPAQL-----------RLPSRLASALS-AQLRLPHPSSPGVLPWRCLS 194
            P  PR     +  P+ +           R PSR  S    A L  P    P  + ++  S
Sbjct: 2424 PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGS 2483

Query: 195  LSVSDLKLPLPPSWPWLGFSAALPA-------AFRPCSAPPAWPRL----------LPLA 237
            L+ + L           GF AALPA       A  P   PP + R            P+ 
Sbjct: 2484 LAHTSLGAG--------GFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR 2535

Query: 238  LAFPVPLGRPRLPPPVFGSTRPALASP 264
              FP  +G P L PPV    +P L  P
Sbjct: 2536 FTFPQAVGEPSLKPPV---PQPGLPPP 2559



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 53/194 (27%), Positives = 65/194 (33%), Gaps = 20/194 (10%)

Query: 86  QGPASVRPPSTPHLLSASALSAQLDSPARPHPRCYPPFALSAPRP-PALGASATAFRSSS 144
           + P S  P  +P   S    +++L  P    P    P AL   RP      S     S  
Sbjct: 446 ESPLSPPPEESP--TSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 145 DPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPL 204
            PP     F     SP      S  + AL   L  P  +SP   P+    LS    +LP 
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT 563

Query: 205 PPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASP 264
            P           P A R   +PP  P   P++   P P   P  PPP      P     
Sbjct: 564 SPP----------PEASR--LSPP--PEESPMS---PPPEESPMSPPPEASRLFPPFEES 606

Query: 265 PLLGSVRSVRLSPP 278
           PL        LSPP
Sbjct: 607 PLSPPPEESPLSPP 620



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 64/233 (27%), Positives = 77/233 (33%), Gaps = 64/233 (27%)

Query: 80   PLDLGFQGPAS-----VRPPSTPHLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALG 134
            P  LG   PA+     +  P+TP  LS SA    L  PA   P    P  L    PP + 
Sbjct: 2110 PGALGSPPPAAAPTIFIGSPTTPAGLSTSA-DGFLKPPAGSVPGPDSPGELFLKLPPQVP 2168

Query: 135  ASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLPHPSSPGVLPWRCLS 194
            A       S DP      F  A A P + R P+      +     P+PS  G        
Sbjct: 2169 AQVP----SQDP------FGLAPAYPLEPRFPT------APPTYPPYPSPTGA------- 2205

Query: 195  LSVSDLKLPLPPSWPWLGFSAALPAAFRPC---SAPPAWPRLLPLA-------------- 237
                      P   P LG S+  P A +P    + PP  PR  P                
Sbjct: 2206 ----------PAQPPMLGASSR-PGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDN 2254

Query: 238  LAFPVPLG-------RPRLPPPVFGSTRPALASPPLLGSVRSVRLSPPGFSFL 283
            LA P   G        P L PP FG +R AL          S    PP   F+
Sbjct: 2255 LAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFV 2307



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 68/261 (26%), Positives = 85/261 (32%), Gaps = 38/261 (14%)

Query: 53  SAPSTGASTSPTRPRLLPRSLGYPLR-HPLDLGFQGPASVRPPSTPHLLSASALSAQLDS 111
           S P  G + +     L     G P   H   +  + P  ++  + P   +   L  QL++
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432

Query: 112 PARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLAS 171
           P        PP   S   PP   +       +S PP   RL      SP    LP   AS
Sbjct: 433 PLNEEMPLLPPPEESPLSPPPEESP------TSPPPEASRL------SPPPEELP---AS 477

Query: 172 ALSAQLRLPHP--SSPGVLPWRCLSLSVSDLKLPLPPSWPWLGF----------SAALPA 219
            L   L L  P   SP   P     LS      P P S P+             S   PA
Sbjct: 478 PLPEALHLSRPLEESPLSPPPEESPLS------PPPESSPFSPLEESPLSPPEESPPSPA 531

Query: 220 AFRPCSAPPAWPRLLPLALAFPV---PLGRPRLPPPVFGSTRPALASPPLLGSVRSVRLS 276
              P S PP    L P     P+   P   P  PPP      P     P+        +S
Sbjct: 532 LETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591

Query: 277 PPGFSFLRFRRF-SSALSASP 296
           PP  +   F  F  S LS  P
Sbjct: 592 PPPEASRLFPPFEESPLSPPP 612



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 59/211 (27%), Positives = 66/211 (31%), Gaps = 46/211 (21%)

Query: 63  PTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLDSPARPH--PRCY 120
           P  P+L PRS             +GP     P  PHL            P  PH  P+  
Sbjct: 729 PEEPQLCPRS-------------EGPHLSPRPEEPHLSPR---------PEEPHLSPQAE 766

Query: 121 PPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPSRLASALSAQLRLP 180
            P     P  P L A           P  P L  +A   P     P  L   LS Q   P
Sbjct: 767 EPHLSPQPEEPCLCAV----------PEEPHLSPQAEG-PHLSPQPEELH--LSPQTEEP 813

Query: 181 HPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLG----FSAALPAAFRPCSAP-PAWPRLLP 235
           H S     P  CLS    +  L      P L      S   P   +P  +P P  P   P
Sbjct: 814 HLSPVPEEP--CLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871

Query: 236 LALAFPVPLGRPRLPPPVFGSTRPALASPPL 266
                P P   P  PPP   S  P L  P L
Sbjct: 872 GQC--PAPEELPLFPPPGEPSLSPLLGEPAL 900


>gi|209413756 synapsin III isoform IIIg [Homo sapiens]
          Length = 579

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 13/109 (11%)

Query: 43  PPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSA 102
           PP  G    A +P    S SP++ RL P+      + PL      P   R P +P L  A
Sbjct: 435 PPPQGGPRQAQSPQPQRSGSPSQQRLSPQG-----QQPLSPQSGSPQQQRSPGSPQLSRA 489

Query: 103 SALSAQLDSPARPHPRCYPPFAL-SAPRPPALGASATAFRSSSDPPARP 150
           S       S + P+    P   L S PRPP  G S +     S  PA P
Sbjct: 490 S-------SGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPP 531


>gi|209413752 synapsin III isoform IIIa [Homo sapiens]
          Length = 580

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 13/109 (11%)

Query: 43  PPGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSA 102
           PP  G    A +P    S SP++ RL P+      + PL      P   R P +P L  A
Sbjct: 436 PPPQGGPRQAQSPQPQRSGSPSQQRLSPQG-----QQPLSPQSGSPQQQRSPGSPQLSRA 490

Query: 103 SALSAQLDSPARPHPRCYPPFAL-SAPRPPALGASATAFRSSSDPPARP 150
           S       S + P+    P   L S PRPP  G S +     S  PA P
Sbjct: 491 S-------SGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPP 532


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/202 (28%), Positives = 76/202 (37%), Gaps = 31/202 (15%)

Query: 88  PASVRPPSTPHLLSASALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPP 147
           PA   P  TP    A  +S ++ SP  P  +   P A  +P P      A      S+ P
Sbjct: 280 PAEELPVETPKRAGAE-VSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPA------SEAP 332

Query: 148 ARPRLFRRASASPAQLRLPSRLASALSA----QLRLPHPSSPGVLPWRCLSLSVSDLKLP 203
            RP    RA+ + A    P R+  A+ A    +  +P PS PG    R  S  +  L+  
Sbjct: 333 DRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTES-PMGALQPD 391

Query: 204 LPPSWPWLGFSAALPAAFRPCSAPPAWPRLLP-------LALAFPVPLGRPRLPPPVFGS 256
               WP            RP S PPA P   P       + +     LG+P  P P   S
Sbjct: 392 EAEEWPG-----------RPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASS 440

Query: 257 TRPALA-SPPLLGSVRSVRLSP 277
              A A SPP   +   +R  P
Sbjct: 441 MASAPASSPPANATAPPLRWGP 462


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 76/263 (28%), Positives = 97/263 (36%), Gaps = 36/263 (13%)

Query: 53  SAPSTGASTSPTRPRLLP-RSLGYPLRHP-LDLGFQGPAS-----VRPPSTPHLLSASAL 105
           S PS GA   PT    LP  S+  P   P L   F  PA      + PPSTP        
Sbjct: 665 SLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTP-------- 716

Query: 106 SAQLDSPARPHPRCYPPFALSAPRP-PALGASATAFRSSSDPPARPRLFRRAS--ASPAQ 162
                 P +P P    P  L+ P P P + A          PP  P     AS   +PAQ
Sbjct: 717 --MPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ 774

Query: 163 LRLPSRLASALSAQLRLPH-----PSSPGVLPWRC---LSLSVSDLKLP-LPPSWPWLGF 213
           L+      + L    ++P      P  P + P      L  ++ DL    +PP  P   F
Sbjct: 775 LKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYF 834

Query: 214 SAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALASPPLLGSVRSV 273
           S A+         PPA P L   A+  P P G P L  P       A A+ PLL      
Sbjct: 835 SPAVILPSLAAPLPPASPALPLQAVKLPHPPGAP-LAMPCRTIVPNAPATIPLLA----- 888

Query: 274 RLSPPGFSFLRFRRFSSALSASP 296
            ++PPG + L      + L   P
Sbjct: 889 -VAPPGVAALSIHSAVAQLPGQP 910



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 61/245 (24%), Positives = 82/245 (33%), Gaps = 54/245 (22%)

Query: 43   PPGTG--SSHLASAPSTGASTSPTR-PRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHL 99
            PPG    S H A A   G    P   P++ P  +     H +      P     P  P L
Sbjct: 891  PPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTL 950

Query: 100  LSASALSAQLD---------SPARPHPRCYPPFALSAPRP-----PALGASATAFRSSSD 145
                 L  Q            P RP     PP  +  P+P     PAL            
Sbjct: 951  PPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL------------ 998

Query: 146  PPARPRLFRRASASPAQLRLPSRLASALS--AQLRLPHPSSPGVLPWRCLSLSVSDLKLP 203
             P RP         P Q  LP + A A +  +Q+ L HP+   V       ++     +P
Sbjct: 999  -PVRP--------EPLQPHLPEQAAPAATPGSQILLGHPAPYAV------DVAAQVPTVP 1043

Query: 204  LPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPPPVFGSTRPALAS 263
            +PP        AA+ +   P    PA P LLP   +    +       P   +T    A+
Sbjct: 1044 VPP--------AAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPAN 1095

Query: 264  PPLLG 268
            PPL G
Sbjct: 1096 PPLPG 1100


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 76/235 (32%), Positives = 92/235 (39%), Gaps = 40/235 (17%)

Query: 54  APSTGASTSPTRPRLLPRSLGY---PLRHPLDLGFQGPASVRPPSTPHLLSASALSAQLD 110
           A S+  +  P  P+  PR+L +    L  P+      P S  PP  P L  + ALS  L 
Sbjct: 635 ARSSNDARRPPAPQPAPRTLSHWSALLSPPVP---PRPPSSGPPPAPPL--SPALSG-LP 688

Query: 111 SPARPHP---RCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRASASPAQLRLPS 167
            PA P+    R  PP+A  A  PPA  AS  AF    +PPA           P  L  P 
Sbjct: 689 RPASPYGSLRRHPPPWAAPAHVPPAPQASWWAF---VEPPA-----VSPEVPPDLLAFPG 740

Query: 168 RLASALSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPP--SWPWLGFSAAL-------- 217
              S   ++ R      PG  P      + S L  P P   S P LG+ + L        
Sbjct: 741 PRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSPQLS 800

Query: 218 --PAAFRPCSAPPA-WPRLL---PLALAFPVPLGRPRLPPPVFGSTRPALASPPL 266
                F+P   PPA  PR L   P        LG P  P P  GS RP   SPPL
Sbjct: 801 LRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLP--GSPRP--PSPPL 851



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 74/232 (31%), Positives = 89/232 (38%), Gaps = 61/232 (26%)

Query: 44  PGTGSSHLASAPSTGAS--TSPTRPRLLP-----RSLGY---PLRHPLDLGFQG---PAS 90
           PG G     + PS   S  T P +P  LP     RSL     P R    LG  G   P S
Sbjct: 784 PGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGS 843

Query: 91  VRPPSTPHLLSASALSAQLDSPAR-PHPRCYPPFALSAPRPPALGASATAFRSSSDPPAR 149
            RPPS P  L  S   + L+ P+R PH                       +R  S+PP R
Sbjct: 844 PRPPSPPLGLCHSPRRSSLNLPSRLPH----------------------TWRRLSEPPTR 881

Query: 150 PRLFRRASASPAQLRLP-SRLASALSAQLRLPHPSSP-----GVLPWRCLSLSVS-DLKL 202
                   A   Q+RLP  R   A + +  L H  SP        PW    L+ S D+ +
Sbjct: 882 --------AVKPQVRLPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVPPLAPSWDVDM 933

Query: 203 P---LPPSWPWLGFSAALPAAFRPCSAPPAWPRLLPLALAFPVPLGRPRLPP 251
           P    PPS PW G + +     R  S PP  P    L L  PVP   P L P
Sbjct: 934 PPTQRPPS-PWPGGAGSR----RGFSRPPPVPENPFLQLLGPVP--SPTLQP 978


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 56/183 (30%), Positives = 69/183 (37%), Gaps = 35/183 (19%)

Query: 121 PPFALSAPRPPALGASATAFRSSSD-----PPARPRLFRRASASPAQLR--LPSRLASA- 172
           PP   + P PP+      +  SS       PPA   +   +  S  Q R   P  L S+ 
Sbjct: 311 PPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSA 370

Query: 173 -LSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWP 231
            LS+   LP    P + P             P+PP        A +P    PC  PP  P
Sbjct: 371 FLSSDFLLPEDPKPRLPP------------PPVPPPLLHYPPPAKVPG-LEPCPPPPFPP 417

Query: 232 RLLPLALAFPVPLGRPRLP----PPVFG-STRPALAS-PPLLGSVRS-------VRLSPP 278
              P AL    PL  PR P    PP  G S  PA A+ PP   SV S       + L P 
Sbjct: 418 MAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPL 477

Query: 279 GFS 281
           G+S
Sbjct: 478 GYS 480



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 26/146 (17%)

Query: 44  PGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSAS 103
           P T +   AS P+T  S +P   +LL  +             +   ++ PP     L  S
Sbjct: 507 PPTLAPATASPPTTAGSNNPCLTQLLTAA-------------KPEQALEPPLVSSTLLRS 553

Query: 104 ALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRAS--ASPA 161
             S Q   P  P     P  A + PRPP   A+          P+RP L  +A   + PA
Sbjct: 554 PGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLA--------PSRPLLVPKAERLSPPA 605

Query: 162 QLRLPSRLASALSAQLRLPHPSSPGV 187
                 RL+  LS+   +P P +  V
Sbjct: 606 PSGSERRLSGDLSS---MPGPGTLSV 628


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 56/183 (30%), Positives = 69/183 (37%), Gaps = 35/183 (19%)

Query: 121 PPFALSAPRPPALGASATAFRSSSD-----PPARPRLFRRASASPAQLR--LPSRLASA- 172
           PP   + P PP+      +  SS       PPA   +   +  S  Q R   P  L S+ 
Sbjct: 311 PPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSA 370

Query: 173 -LSAQLRLPHPSSPGVLPWRCLSLSVSDLKLPLPPSWPWLGFSAALPAAFRPCSAPPAWP 231
            LS+   LP    P + P             P+PP        A +P    PC  PP  P
Sbjct: 371 FLSSDFLLPEDPKPRLPP------------PPVPPPLLHYPPPAKVPG-LEPCPPPPFPP 417

Query: 232 RLLPLALAFPVPLGRPRLP----PPVFG-STRPALAS-PPLLGSVRS-------VRLSPP 278
              P AL    PL  PR P    PP  G S  PA A+ PP   SV S       + L P 
Sbjct: 418 MAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPL 477

Query: 279 GFS 281
           G+S
Sbjct: 478 GYS 480



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 26/146 (17%)

Query: 44  PGTGSSHLASAPSTGASTSPTRPRLLPRSLGYPLRHPLDLGFQGPASVRPPSTPHLLSAS 103
           P T +   AS P+T  S +P   +LL  +             +   ++ PP     L  S
Sbjct: 507 PPTLAPATASPPTTAGSNNPCLTQLLTAA-------------KPEQALEPPLVSSTLLRS 553

Query: 104 ALSAQLDSPARPHPRCYPPFALSAPRPPALGASATAFRSSSDPPARPRLFRRAS--ASPA 161
             S Q   P  P     P  A + PRPP   A+          P+RP L  +A   + PA
Sbjct: 554 PGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLA--------PSRPLLVPKAERLSPPA 605

Query: 162 QLRLPSRLASALSAQLRLPHPSSPGV 187
                 RL+  LS+   +P P +  V
Sbjct: 606 PSGSERRLSGDLSS---MPGPGTLSV 628


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,212,250
Number of Sequences: 37866
Number of extensions: 1072545
Number of successful extensions: 7107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 701
Number of HSP's that attempted gapping in prelim test: 5553
Number of HSP's gapped (non-prelim): 1812
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.