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Search of human proteins with 169172917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169172917 PREDICTED: hypothetical protein LOC346702 [Homo
sapiens]
(213 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169172917 PREDICTED: hypothetical protein LOC346702 [Homo sap... 451 e-127
gi|169173186 PREDICTED: similar to hCG1643218 [Homo sapiens] 447 e-126
gi|239749352 PREDICTED: similar to hCG1643218 [Homo sapiens] 447 e-126
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 151 5e-37
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 115 4e-26
gi|4503627 coagulation factor XI precursor [Homo sapiens] 105 4e-23
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 102 2e-22
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 99 3e-21
gi|13994276 marapsin [Homo sapiens] 96 3e-20
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 92 4e-19
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 92 4e-19
gi|58218970 protease, serine, 36 [Homo sapiens] 91 9e-19
gi|4506143 neurotrypsin precursor [Homo sapiens] 90 2e-18
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 89 2e-18
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 89 4e-18
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 89 4e-18
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 89 4e-18
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 89 4e-18
gi|223942069 enterokinase precursor [Homo sapiens] 88 5e-18
gi|34098976 marapsin 2 [Homo sapiens] 87 1e-17
gi|33695155 hepsin [Homo sapiens] 86 2e-17
gi|4504481 hepsin [Homo sapiens] 86 2e-17
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 86 3e-17
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 86 3e-17
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 85 4e-17
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 85 4e-17
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 84 7e-17
gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 84 9e-17
gi|4503649 coagulation factor IX preproprotein [Homo sapiens] 82 4e-16
gi|11415040 matriptase [Homo sapiens] 82 4e-16
>gi|169172917 PREDICTED: hypothetical protein LOC346702 [Homo
sapiens]
Length = 213
Score = 451 bits (1161), Expect = e-127
Identities = 213/213 (100%), Positives = 213/213 (100%)
Query: 1 MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII 60
MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII
Sbjct: 1 MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII 60
Query: 61 HKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL 120
HKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL
Sbjct: 61 HKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL 120
Query: 121 NMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG 180
NMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG
Sbjct: 121 NMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG 180
Query: 181 TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP
Sbjct: 181 TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
>gi|169173186 PREDICTED: similar to hCG1643218 [Homo sapiens]
Length = 213
Score = 447 bits (1151), Expect = e-126
Identities = 211/213 (99%), Positives = 212/213 (99%)
Query: 1 MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII 60
MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII
Sbjct: 1 MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII 60
Query: 61 HKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL 120
HK YKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL
Sbjct: 61 HKYYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL 120
Query: 121 NMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG 180
NMHLEKLRVVQISRKECAKR+NQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG
Sbjct: 121 NMHLEKLRVVQISRKECAKRVNQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG 180
Query: 181 TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP
Sbjct: 181 TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
>gi|239749352 PREDICTED: similar to hCG1643218 [Homo sapiens]
Length = 213
Score = 447 bits (1151), Expect = e-126
Identities = 211/213 (99%), Positives = 212/213 (99%)
Query: 1 MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII 60
MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII
Sbjct: 1 MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII 60
Query: 61 HKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL 120
HK YKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL
Sbjct: 61 HKYYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYDQYDDL 120
Query: 121 NMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG 180
NMHLEKLRVVQISRKECAKR+NQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG
Sbjct: 121 NMHLEKLRVVQISRKECAKRVNQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYG 180
Query: 181 TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP
Sbjct: 181 TQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 151 bits (381), Expect = 5e-37
Identities = 77/207 (37%), Positives = 124/207 (59%), Gaps = 10/207 (4%)
Query: 7 CGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDYKP 66
CGGSIL+ WW+LTAAHC ++ ++VV+GT ++ E K+V +I+HKD+K
Sbjct: 93 CGGSILNKWWILTAAHCLYSE--ELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKR 150
Query: 67 PQLDSDLSLLLLATPVQFSNFKMPVCL--QEEERTWDWCWMAQWVTTNGYDQYDDLNMHL 124
+D+D++LLLLA+P++ + K+P+CL Q TW CW+A W TN D+ + + L
Sbjct: 151 ANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQTNAADK-NSVKTDL 209
Query: 125 EKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYGTQRL 184
K +V + +EC+K +L++NM+CA + S+ +GDSG PLVC ++
Sbjct: 210 MKAPMVIMDWEECSKMFPKLTKNMLCAGYKN-----ESYDACKGDSGGPLVCTPEPGEKW 264
Query: 185 FQVGVFSGGIRSGSRGRPGMFVSVAQF 211
+QVG+ S G G + PG++ S+ +
Sbjct: 265 YQVGIISWGKSCGEKNTPGIYTSLVNY 291
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 115 bits (287), Expect = 4e-26
Identities = 68/222 (30%), Positives = 121/222 (54%), Gaps = 28/222 (12%)
Query: 2 SRKHLCGGSILHWWWVLTAAHCFRRTLLD------MAVVNVTVVMGTRTFSNIHSERKQV 55
+++HLCGGS++ WVLTAAHCF L ++N++ + FS Q+
Sbjct: 414 AQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFS-------QI 466
Query: 56 QKVIIHKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERT---WDWCWMAQWVTTN 112
+++IIH++YK + + D++L+ L P+ ++ F+ P+CL + T + CW+ W +
Sbjct: 467 KEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSK 526
Query: 113 GYDQYDDLNMHLEKLRVVQISRKECAKRIN--QLSRNMICAWNEPGTNDCSSFPHSQGDS 170
+ ++ L+K+ + ++ +EC KR ++++ M+CA + G D +GDS
Sbjct: 527 EKGEIQNI---LQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDA-----CKGDS 578
Query: 171 GAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
G PLVC G RL VG+ S G R +PG++ VA+++
Sbjct: 579 GGPLVCKHNGMWRL--VGITSWGEGCARREQPGVYTKVAEYM 618
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 105 bits (261), Expect = 4e-23
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 36/226 (15%)
Query: 2 SRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNI--HSERKQ----- 54
+++HLCGGSI+ W+LTAAHCF V R +S I SE K+
Sbjct: 411 TQRHLCGGSIIGNQWILTAAHCF---------YGVESPKILRVYSGILNQSEIKEDTSFF 461
Query: 55 -VQKVIIHKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQ---EEERTWDWCWMAQWVT 110
VQ++IIH YK + D++LL L T V +++ + P+CL + + CW+ W
Sbjct: 462 GVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGW-- 519
Query: 111 TNGYDQY-DDLNMHLEKLRVVQISRKECAKRI--NQLSRNMICA-WNEPGTNDCSSFPHS 166
GY + D + L+K ++ ++ +EC KR ++++ MICA + E G + C
Sbjct: 520 --GYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDAC------ 571
Query: 167 QGDSGAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
+GDSG PL C L VG+ S G R RPG++ +V +++
Sbjct: 572 KGDSGGPLSCKHNEVWHL--VGITSWGEGCAQRERPGVYTNVVEYV 615
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 102 bits (254), Expect = 2e-22
Identities = 72/216 (33%), Positives = 107/216 (49%), Gaps = 22/216 (10%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDY 64
HLCGGS++ W++TAAHC L + T+ +G + + + V+K++ H Y
Sbjct: 240 HLCGGSVITPLWIITAAHCVYDLYLPKSW---TIQVGLVSLLDNPAPSHLVEKIVYHSKY 296
Query: 65 KPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTW---DWCWMAQWVTTNGYDQYDDLN 121
KP +L +D++L+ LA P+ F+ PVCL E + CW + W T D D +
Sbjct: 297 KPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATE--DGAGDAS 354
Query: 122 MHLEKLRVVQISRKECAKRI---NQLSRNMICA-WNEPGTNDCSSFPHSQGDSGAPLVCA 177
L V IS K C R +S +M+CA + G + C QGDSG PLVC
Sbjct: 355 PVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSC------QGDSGGPLVCQ 408
Query: 178 IYGTQRLFQ-VGVFSGGIRSGSRGRPGMFVSVAQFI 212
+RL++ VG S GI +PG++ V F+
Sbjct: 409 ---ERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFL 441
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 99.0 bits (245), Expect = 3e-21
Identities = 70/217 (32%), Positives = 109/217 (50%), Gaps = 21/217 (9%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHS--ERKQVQKVIIHK 62
H+CGG+++ WVLTAAHCF T + + V GT SN+H E + ++II+
Sbjct: 349 HICGGTLIDAQWVLTAAHCFFVT-REKVLEGWKVYAGT---SNLHQLPEAASIAEIIINS 404
Query: 63 DYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTW---DWCWMAQWVTTNGYDQYDD 119
+Y + D D++L+ L+ P+ S P CL +T+ + CW+ + T D D
Sbjct: 405 NYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETD--DK 462
Query: 120 LNMHLEKLRVVQISRKECAKRI---NQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVC 176
+ L +++V I K+C + + L+ M+CA + G D QGDSG PLVC
Sbjct: 463 TSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRD-----SCQGDSGGPLVC 517
Query: 177 AIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
R + GV S G G R +PG++ V + +P
Sbjct: 518 E--QNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLP 552
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 95.5 bits (236), Expect = 3e-20
Identities = 68/219 (31%), Positives = 105/219 (47%), Gaps = 26/219 (11%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTF--SNIHSERKQVQKVIIHK 62
H CGGS++ WVLTAAHCFR T V++G R H+ +V++V +
Sbjct: 58 HFCGGSLIAEQWVLTAAHCFRNT---SETSLYQVLLGARQLVQPGPHAMYARVRQVESNP 114
Query: 63 DYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDW---CWMAQWVTTNGYDQYDD 119
Y+ +D++L+ L PV F+N+ +PVCL + ++ CW+ W + + D +
Sbjct: 115 LYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPE 174
Query: 120 LNMHLEKLRVVQISRKEC----------AKRINQLSRNMICAWNEPGTNDCSSFPHSQGD 169
+ L+KL V I +C + + +M+CA E G D +GD
Sbjct: 175 PRI-LQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDA-----CKGD 228
Query: 170 SGAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSV 208
SG PLVC + Q Q GV S G + RPG+++ V
Sbjct: 229 SGGPLVCLV--GQSWLQAGVISWGEGCARQNRPGVYIRV 265
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 91.7 bits (226), Expect = 4e-19
Identities = 69/214 (32%), Positives = 103/214 (48%), Gaps = 34/214 (15%)
Query: 6 LCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQ--VQKVIIHKD 63
LCGG ++H WVLTAAHC + N+ V +G S ++Q V + +IH D
Sbjct: 46 LCGGVLIHPLWVLTAAHCKK--------PNLQVFLGKHNLRQRESSQEQSSVVRAVIHPD 97
Query: 64 YKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEE-ERTWDWCWMAQWVTTNGYDQYDDLN- 121
Y D D+ LL LA P + S P+ L+ + C + W T D D +
Sbjct: 98 YDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQC 157
Query: 122 --MHLEKLRVVQISRKECAKRI-NQLSRNMICAWNEP-GTNDCSSFPHSQGDSGAPLVCA 177
+HL +SR+EC Q+++NM+CA +E G + C QGDSG PLVC
Sbjct: 158 AYIHL-------VSREECEHAYPGQITQNMLCAGDEKYGKDSC------QGDSGGPLVCG 204
Query: 178 IYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
+ + V G I GS+ +PG++ +V ++
Sbjct: 205 DH-----LRGLVSWGNIPCGSKEKPGVYTNVCRY 233
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 91.7 bits (226), Expect = 4e-19
Identities = 69/214 (32%), Positives = 103/214 (48%), Gaps = 34/214 (15%)
Query: 6 LCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQ--VQKVIIHKD 63
LCGG ++H WVLTAAHC + N+ V +G S ++Q V + +IH D
Sbjct: 46 LCGGVLIHPLWVLTAAHCKK--------PNLQVFLGKHNLRQRESSQEQSSVVRAVIHPD 97
Query: 64 YKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEE-ERTWDWCWMAQWVTTNGYDQYDDLN- 121
Y D D+ LL LA P + S P+ L+ + C + W T D D +
Sbjct: 98 YDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQC 157
Query: 122 --MHLEKLRVVQISRKECAKRI-NQLSRNMICAWNEP-GTNDCSSFPHSQGDSGAPLVCA 177
+HL +SR+EC Q+++NM+CA +E G + C QGDSG PLVC
Sbjct: 158 AYIHL-------VSREECEHAYPGQITQNMLCAGDEKYGKDSC------QGDSGGPLVCG 204
Query: 178 IYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
+ + V G I GS+ +PG++ +V ++
Sbjct: 205 DH-----LRGLVSWGNIPCGSKEKPGVYTNVCRY 233
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 90.5 bits (223), Expect = 9e-19
Identities = 68/221 (30%), Positives = 100/221 (45%), Gaps = 22/221 (9%)
Query: 5 HLCGGSILHWWWVLTAAHCF--RRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHK 62
H+CGGS++ WVL+AAHCF TL A +V + + ++ + + V +++
Sbjct: 70 HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPA 129
Query: 63 DYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTW---DWCWMAQWVTTNGYDQYDD 119
+Y +L +DL+LL LA+P PVCL + CW W D
Sbjct: 130 NYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPL-P 188
Query: 120 LNMHLEKLRVVQISRKECAKRIN---------QLSRNMICAWNEPGTNDCSSFPHSQGDS 170
L L+++ + + C + Q+ M+CA G D QGDS
Sbjct: 189 LPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDT-----CQGDS 243
Query: 171 GAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
G PLVC G R FQ G+ S G G R RPG+F +VA +
Sbjct: 244 GGPLVCEEGG--RWFQAGITSFGFGCGRRNRPGVFTAVATY 282
Score = 36.6 bits (83), Expect = 0.016
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 6 LCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII----- 60
+C G +L WVL A HC R V + V +G S++ + QV +++I
Sbjct: 614 VCTGILLAPGWVLAATHCVLRP-GSTTVPYIEVYLGRAGASSL-PQGHQVSRLVISIRLP 671
Query: 61 -HKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEE-RTWDWCWMAQW 108
H +PP L+LL L++ V+ S +P+CL CW+ W
Sbjct: 672 QHLGLRPP-----LALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGW 716
Score = 35.4 bits (80), Expect = 0.036
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 6/105 (5%)
Query: 7 CGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDYKP 66
C G+++ WVL A CF + S +ER V +++ H++
Sbjct: 348 CHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAER--VARLVQHENASW 405
Query: 67 PQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTW---DWCWMAQW 108
SDL+LL L TPV S PVCL E + C +A+W
Sbjct: 406 DNA-SDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARW 449
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 89.7 bits (221), Expect = 2e-18
Identities = 63/217 (29%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 6 LCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDYK 65
LCG ++L WVLTAAHCF+R V V E VQ+++IH++Y+
Sbjct: 660 LCGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYR 719
Query: 66 PPQLDSDLSLLLLATP----VQFSNFKMPVCL----QEEERTWDWCWMAQWVTTNGYDQY 117
P + D D++L+ L P +FS+ +P CL + ++T C++ W T
Sbjct: 720 PDRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTG----- 774
Query: 118 DDLNMHLEKLRVVQISRKECAKRI-NQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVC 176
+ L++ + + ++ C +R + + M+CA N ++ QGDSG PL+C
Sbjct: 775 RAYSRTLQQAAIPLLPKRFCEERYKGRFTGRMLCAGN---LHEHKRVDSCQGDSGGPLMC 831
Query: 177 AIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFIP 213
G + GV S G G + PG++ V+ F+P
Sbjct: 832 ERPG-ESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVP 867
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 89.4 bits (220), Expect = 2e-18
Identities = 70/230 (30%), Positives = 114/230 (49%), Gaps = 34/230 (14%)
Query: 1 MSRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFS------NIHSERKQ 54
+ R+H CGGS+L WVL+AAHCF++ TV +G T +S R +
Sbjct: 74 LRRRHRCGGSLLSRRWVLSAAHCFQKHYYPS---EWTVQLGELTSRPTPWNLRAYSSRYK 130
Query: 55 VQKVIIHKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDW-----CWMAQW- 108
VQ +I++ D L +D++LL LA+ V ++ + P+C+ E T+++ CW+ W
Sbjct: 131 VQDIIVNPD-ALGVLRNDIALLRLASSVTYNAYIQPICI--ESSTFNFVHRPDCWVTGWG 187
Query: 109 -VTTNGYDQYDDLNMHLEKLRVVQISRKECAKRINQLSR------NMICAWNEPGTNDCS 161
++ +G N L + +V ++ C Q S +M CA E G+ D
Sbjct: 188 LISPSGTPLPPPYN--LREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDGSVDT- 244
Query: 162 SFPHSQGDSGAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
+GDSG PLVC G +QVG+ S G+ G RPG++ +++ +
Sbjct: 245 ----CKGDSGGPLVCDKDGL--WYQVGIVSWGMDCGQPNRPGVYTNISVY 288
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 88.6 bits (218), Expect = 4e-18
Identities = 67/219 (30%), Positives = 99/219 (45%), Gaps = 25/219 (11%)
Query: 2 SRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIH 61
S H CGGS++ WVLTAAHC R + +G K ++ +I
Sbjct: 183 SNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIG-----RWDQAWKHLEDIIFP 237
Query: 62 KDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQE---EERTWDWCWMAQWVTTNG----- 113
++ L SD++L LLA V +S+ P CL E E CW+ W +
Sbjct: 238 SNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGP 297
Query: 114 ---YDQYDDLNMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDS 170
Q +LN+ + + K +K ++R +C +N+ G + C QGDS
Sbjct: 298 MPLVLQETELNIMRHEKCCEMLKNKNISKS-KMVTRGTVCGYNDQGKDAC------QGDS 350
Query: 171 GAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVA 209
G PLVC + GT QVG+ S GI G +G PG++ V+
Sbjct: 351 GGPLVCELNGT--WVQVGIVSWGIGCGRKGYPGVYTEVS 387
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 88.6 bits (218), Expect = 4e-18
Identities = 67/219 (30%), Positives = 99/219 (45%), Gaps = 25/219 (11%)
Query: 2 SRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIH 61
S H CGGS++ WVLTAAHC R + +G K ++ +I
Sbjct: 183 SNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIG-----RWDQAWKHLEDIIFP 237
Query: 62 KDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQE---EERTWDWCWMAQWVTTNG----- 113
++ L SD++L LLA V +S+ P CL E E CW+ W +
Sbjct: 238 SNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGP 297
Query: 114 ---YDQYDDLNMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDS 170
Q +LN+ + + K +K ++R +C +N+ G + C QGDS
Sbjct: 298 MPLVLQETELNIMRHEKCCEMLKNKNISKS-KMVTRGTVCGYNDQGKDAC------QGDS 350
Query: 171 GAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVA 209
G PLVC + GT QVG+ S GI G +G PG++ V+
Sbjct: 351 GGPLVCELNGT--WVQVGIVSWGIGCGRKGYPGVYTEVS 387
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 88.6 bits (218), Expect = 4e-18
Identities = 67/219 (30%), Positives = 99/219 (45%), Gaps = 25/219 (11%)
Query: 2 SRKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIH 61
S H CGGS++ WVLTAAHC R + +G K ++ +I
Sbjct: 183 SNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIG-----RWDQAWKHLEDIIFP 237
Query: 62 KDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQE---EERTWDWCWMAQWVTTNG----- 113
++ L SD++L LLA V +S+ P CL E E CW+ W +
Sbjct: 238 SNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGP 297
Query: 114 ---YDQYDDLNMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDS 170
Q +LN+ + + K +K ++R +C +N+ G + C QGDS
Sbjct: 298 MPLVLQETELNIMRHEKCCEMLKNKNISKS-KMVTRGTVCGYNDQGKDAC------QGDS 350
Query: 171 GAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVA 209
G PLVC + GT QVG+ S GI G +G PG++ V+
Sbjct: 351 GGPLVCELNGT--WVQVGIVSWGIGCGRKGYPGVYTEVS 387
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 88.6 bits (218), Expect = 4e-18
Identities = 72/217 (33%), Positives = 101/217 (46%), Gaps = 19/217 (8%)
Query: 4 KHLCGGSILHWWWVLTAAHC---FRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVII 60
+H CGGS+L WV+TAAHC FR L V+ +V + + + V+++I
Sbjct: 240 RHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPH---QGALVERIIP 296
Query: 61 HKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTW---DWCWMAQWVTTNGYDQY 117
H Y D D++LL L T + FS+ VCL +E+ + CW++ W T+ Y
Sbjct: 297 HPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTY 356
Query: 118 --DDLNMHLEKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLV 175
D L + L Q+ C L+ M+CA G D QGDSG PLV
Sbjct: 357 SSDMLQDTVVPLFSTQLCNSSCVYS-GALTPRMLCAGYLDGRADA-----CQGDSGGPLV 410
Query: 176 CAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
C T RL VGV S G PG++ VA+F+
Sbjct: 411 CPDGDTWRL--VGVVSWGRGCAEPNHPGVYAKVAEFL 445
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 88.2 bits (217), Expect = 5e-18
Identities = 63/215 (29%), Positives = 113/215 (52%), Gaps = 22/215 (10%)
Query: 6 LCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSER---KQVQKVIIHK 62
LCG S++ W+++AAHC L+ + T ++G SN+ S + + + +++I+
Sbjct: 809 LCGASLVSSDWLVSAAHCVYGRNLEPS--KWTAILGLHMKSNLTSPQTVPRLIDEIVINP 866
Query: 63 DYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWD---WCWMAQWVTTNGYDQYDD 119
Y + D+D++++ L V ++++ P+CL EE + + C +A W T Q
Sbjct: 867 HYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTV--VYQGTT 924
Query: 120 LNMHLEKLRVVQISRKECAKRINQ--LSRNMICA-WNEPGTNDCSSFPHSQGDSGAPLVC 176
N+ L++ V +S + C +++ + ++ NMICA + E G + C QGDSG PL+C
Sbjct: 925 ANI-LQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSC------QGDSGGPLMC 977
Query: 177 AIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
R F GV S G + RPG++ V++F
Sbjct: 978 --QENNRWFLAGVTSFGYKCALPNRPGVYARVSRF 1010
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 87.0 bits (214), Expect = 1e-17
Identities = 63/213 (29%), Positives = 105/213 (49%), Gaps = 17/213 (7%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDY 64
H+CGGSIL+ +WVL+AAHCF R ++ + ++ V + + H++ +V +VI+H Y
Sbjct: 83 HVCGGSILNEYWVLSAAHCFHRD-KNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTY 141
Query: 65 KP-PQLDSDLSLLLLATPVQFSNFKMPVCL--QEEERTWDWCWMAQWVTTNGYDQYDDLN 121
+ + D++L+ L T + FS +PVCL E T CW W + + D
Sbjct: 142 EMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSANCWATGWGLVSKQGETSD-- 199
Query: 122 MHLEKLRVVQISRKECAKRINQLS---RNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAI 178
L+++++ I C +S +M+CA + +GDSG PLVC
Sbjct: 200 -ELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTV-----CEGDSGGPLVCEF 253
Query: 179 YGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
+ Q+G+ S G + PG++ SV+ F
Sbjct: 254 --NRSWLQIGIVSWGRGCSNPLYPGVYASVSYF 284
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 86.3 bits (212), Expect = 2e-17
Identities = 70/222 (31%), Positives = 101/222 (45%), Gaps = 26/222 (11%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDY 64
HLCGGS+L WVLTAAHCF + + V G ++ H + VQ V+ H Y
Sbjct: 186 HLCGGSLLSGDWVLTAAHCFPER--NRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGY 243
Query: 65 KP------PQLDSDLSLLLLATPVQFSNFKMPVCLQEEERT---WDWCWMAQWVTTNGYD 115
P + +D++L+ L++P+ + + PVCL + C + W T Y
Sbjct: 244 LPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG 303
Query: 116 QYDDLNMHLEKLRVVQISRKECAKRI---NQLSRNMICA-WNEPGTNDCSSFPHSQGDSG 171
Q + L++ RV IS C NQ+ M CA + E G + C QGDSG
Sbjct: 304 QQAGV---LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDAC------QGDSG 354
Query: 172 APLVC--AIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
P VC +I T R G+ S G +PG++ V+ F
Sbjct: 355 GPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDF 396
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 86.3 bits (212), Expect = 2e-17
Identities = 70/222 (31%), Positives = 101/222 (45%), Gaps = 26/222 (11%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDY 64
HLCGGS+L WVLTAAHCF + + V G ++ H + VQ V+ H Y
Sbjct: 186 HLCGGSLLSGDWVLTAAHCFPER--NRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGY 243
Query: 65 KP------PQLDSDLSLLLLATPVQFSNFKMPVCLQEEERT---WDWCWMAQWVTTNGYD 115
P + +D++L+ L++P+ + + PVCL + C + W T Y
Sbjct: 244 LPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG 303
Query: 116 QYDDLNMHLEKLRVVQISRKECAKRI---NQLSRNMICA-WNEPGTNDCSSFPHSQGDSG 171
Q + L++ RV IS C NQ+ M CA + E G + C QGDSG
Sbjct: 304 QQAGV---LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDAC------QGDSG 354
Query: 172 APLVC--AIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
P VC +I T R G+ S G +PG++ V+ F
Sbjct: 355 GPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDF 396
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 85.5 bits (210), Expect = 3e-17
Identities = 65/227 (28%), Positives = 114/227 (50%), Gaps = 30/227 (13%)
Query: 4 KHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQ---VQKVII 60
+ LCGG ++ W+L+AAHCF+ ++TV++G RT+ + E +Q V+K I+
Sbjct: 339 RFLCGGILISSCWILSAAHCFQER---FPPHHLTVILG-RTYRVVPGEEEQKFEVEKYIV 394
Query: 61 HKDYKPPQLDSDLSLLLLATP----VQFSNFKMPVCLQEEE---RTWDWCWMAQWVTTNG 113
HK++ D+D++LL L + Q S+ VCL + W C + +G
Sbjct: 395 HKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECEL------SG 448
Query: 114 YDQYDDLN-MHLEKLRVVQISRKECAKRINQ------LSRNMICAWN-EPGTNDCSSFPH 165
Y +++ L+ + E+L+ + ++ +Q ++ NM+CA + G +
Sbjct: 449 YGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDA 508
Query: 166 SQGDSGAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
QGDSG PLVC G R+ VG+ S G+ G + PG++ V ++
Sbjct: 509 CQGDSGGPLVCLNDG--RMTLVGIISWGLGCGQKDVPGVYTKVTNYL 553
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 85.5 bits (210), Expect = 3e-17
Identities = 65/227 (28%), Positives = 114/227 (50%), Gaps = 30/227 (13%)
Query: 4 KHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQ---VQKVII 60
+ LCGG ++ W+L+AAHCF+ ++TV++G RT+ + E +Q V+K I+
Sbjct: 293 RFLCGGILISSCWILSAAHCFQER---FPPHHLTVILG-RTYRVVPGEEEQKFEVEKYIV 348
Query: 61 HKDYKPPQLDSDLSLLLLATP----VQFSNFKMPVCLQEEE---RTWDWCWMAQWVTTNG 113
HK++ D+D++LL L + Q S+ VCL + W C + +G
Sbjct: 349 HKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECEL------SG 402
Query: 114 YDQYDDLN-MHLEKLRVVQISRKECAKRINQ------LSRNMICAWN-EPGTNDCSSFPH 165
Y +++ L+ + E+L+ + ++ +Q ++ NM+CA + G +
Sbjct: 403 YGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDA 462
Query: 166 SQGDSGAPLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
QGDSG PLVC G R+ VG+ S G+ G + PG++ V ++
Sbjct: 463 CQGDSGGPLVCLNDG--RMTLVGIISWGLGCGQKDVPGVYTKVTNYL 507
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 85.1 bits (209), Expect = 4e-17
Identities = 63/221 (28%), Positives = 99/221 (44%), Gaps = 26/221 (11%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDY 64
H CGGS++H WVLTAAHC + D+A + V + + V ++I+H +
Sbjct: 57 HFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL---REQHLYYQDQLLPVSRIIVHPQF 113
Query: 65 KPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWD---WCWMAQWVTTNGYDQYDDLN 121
Q+ +D++LL L PV S+ V L T+ CW+ W + D+
Sbjct: 114 YTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDN-DERLPPP 172
Query: 122 MHLEKLRVVQISRKECAKR----------INQLSRNMICAWNEPGTNDCSSFPHSQGDSG 171
L++++V + C + + + +M+CA N + C QGDSG
Sbjct: 173 FPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGN-TRRDSC------QGDSG 225
Query: 172 APLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
PLVC + GT Q GV S G RPG++ V ++
Sbjct: 226 GPLVCKVNGT--WLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 85.1 bits (209), Expect = 4e-17
Identities = 63/221 (28%), Positives = 99/221 (44%), Gaps = 26/221 (11%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDY 64
H CGGS++H WVLTAAHC + D+A + V + + V ++I+H +
Sbjct: 57 HFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL---REQHLYYQDQLLPVSRIIVHPQF 113
Query: 65 KPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWD---WCWMAQWVTTNGYDQYDDLN 121
Q+ +D++LL L PV S+ V L T+ CW+ W + D+
Sbjct: 114 YTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDN-DERLPPP 172
Query: 122 MHLEKLRVVQISRKECAKR----------INQLSRNMICAWNEPGTNDCSSFPHSQGDSG 171
L++++V + C + + + +M+CA N + C QGDSG
Sbjct: 173 FPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGN-TRRDSC------QGDSG 225
Query: 172 APLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
PLVC + GT Q GV S G RPG++ V ++
Sbjct: 226 GPLVCKVNGT--WLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 84.3 bits (207), Expect = 7e-17
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 20/214 (9%)
Query: 4 KHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQV--QKVIIH 61
+H CG +++ W+L+AAHCF T ++ V +GT + + ++ ++V++H
Sbjct: 526 RHFCGATVVGDRWLLSAAHCFNHTKVEQ----VRAHLGTASLLGLGGSPVKIGLRRVVLH 581
Query: 62 KDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQ---EEERTWDWCWMAQWVTT-NGYDQY 117
Y P LD DL++L LA+P+ F+ + PVCL ++ C ++ W T G
Sbjct: 582 PLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATK 641
Query: 118 DDLNMHLEKLRVVQISRKECAKRIN-QLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVC 176
+L L+K V I +K C+ N L+ MICA G D QGDSG PL C
Sbjct: 642 PEL---LQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVD-----SCQGDSGGPLAC 693
Query: 177 AIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQ 210
+ G+ S GI +PG++ + +
Sbjct: 694 E-EAPGVFYLAGIVSWGIGCAQVKKPGVYTRITR 726
Score = 82.0 bits (201), Expect = 3e-16
Identities = 66/218 (30%), Positives = 101/218 (46%), Gaps = 23/218 (10%)
Query: 2 SRKHLCGGSILHWWWVLTAAHCFRR---TLLDMAVVNVTVVMGTRTFSNIHSERKQVQKV 58
+++H CG +I++ W+++AAHCF +A V T + G S + R QV ++
Sbjct: 223 NKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSG----SEASTVRAQVVQI 278
Query: 59 IIHKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTW---DWCWMAQWVTTNGYD 115
+ H Y D D+++L L +P+ F PVCL + C ++ W GY
Sbjct: 279 VKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGW----GYL 334
Query: 116 QYDDLNMH--LEKLRVVQISRKECAKRI-NQLSRNMICAWNEPGTNDCSSFPHSQGDSGA 172
+ D L L+K V + + CA + L+ M+CA G D QGDSG
Sbjct: 335 KEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVD-----SCQGDSGG 389
Query: 173 PLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQ 210
PLVC + R F G+ S GI RPG++ V +
Sbjct: 390 PLVCE-EPSGRFFLAGIVSWGIGCAEARRPGVYARVTR 426
Score = 73.2 bits (178), Expect = 2e-13
Identities = 64/212 (30%), Positives = 97/212 (45%), Gaps = 18/212 (8%)
Query: 3 RKHLCGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHK 62
R+H CG ++ W+L+AAHCF + +GT S + ++V ++ H
Sbjct: 849 REHRCGAVLVAERWLLSAAHCFD---VYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHP 905
Query: 63 DYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQE-EERTWDW--CWMAQWVTTNGYDQYDD 119
Y LD D++LL LA PV+ S P+CL E R D C + W + +
Sbjct: 906 FYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVR---EGGS 962
Query: 120 LNMHLEKLRVVQISRKECAKRIN-QLSRNMICA-WNEPGTNDCSSFPHSQGDSGAPLVCA 177
+ L+K V +S + C + Q+S M+CA + + G + CS GD+G PL C
Sbjct: 963 MARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCS------GDAGGPLACR 1016
Query: 178 IYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVA 209
+ R GV S G G PG++ VA
Sbjct: 1017 -EPSGRWVLTGVTSWGYGCGRPHFPGVYTRVA 1047
>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
Length = 348
Score = 84.0 bits (206), Expect = 9e-17
Identities = 59/212 (27%), Positives = 107/212 (50%), Gaps = 22/212 (10%)
Query: 5 HLCGGSILHWWWVLTAAHCFRRT---LLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIH 61
H+CGG+++ WVLTAAHC + L+ AV+ + G H+++ +++ +IIH
Sbjct: 105 HVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYP----HTKKIKIKAIIIH 160
Query: 62 KDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEE-RTWDW---CWMAQWVTTNGYDQY 117
++ +D++L L V+++++ P+CL + + D C+++ W T
Sbjct: 161 PNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNA 220
Query: 118 DDLNMHLEKLRVVQISRKECAKRINQ---LSRNMICAWNEPGTNDCSSFPHSQGDSGAPL 174
++ L+ V ISR+ C + + CA +E G +F +GDSG PL
Sbjct: 221 TNI---LQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDG-----AFDTCRGDSGGPL 272
Query: 175 VCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFV 206
+C + +R F +G+ S G G RG PG+++
Sbjct: 273 MCYLPEYKRFFVMGITSYGHGCGRRGFPGVYI 304
>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
Length = 461
Score = 81.6 bits (200), Expect = 4e-16
Identities = 64/219 (29%), Positives = 109/219 (49%), Gaps = 32/219 (14%)
Query: 7 CGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNI-HSERKQ-VQKVIIHKDY 64
CGGSI++ W++TAAHC V +TVV G H+E+K+ V ++I H +Y
Sbjct: 252 CGGSIVNEKWIVTAAHCVE------TGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNY 305
Query: 65 KPP--QLDSDLSLLLLATPVQFSNFKMPVCLQEEERT-----WDWCWMAQW--VTTNGYD 115
+ + D++LL L P+ +++ P+C+ ++E T + +++ W V G
Sbjct: 306 NAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRS 365
Query: 116 QYDDLNMHLEKLRVVQISRKECAKRIN-QLSRNMICA-WNEPGTNDCSSFPHSQGDSGAP 173
+ L+ LRV + R C + + NM CA ++E G + C QGDSG P
Sbjct: 366 A-----LVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSC------QGDSGGP 414
Query: 174 LVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQFI 212
V + GT F G+ S G +G+ G++ V++++
Sbjct: 415 HVTEVEGTS--FLTGIISWGEECAMKGKYGIYTKVSRYV 451
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 81.6 bits (200), Expect = 4e-16
Identities = 59/219 (26%), Positives = 105/219 (47%), Gaps = 16/219 (7%)
Query: 1 MSRKHLCGGSILHWWWVLTAAHCF--RRTLLDMAVVNVTVVMGTRTFSNIHS---ERKQV 55
+ + H+CG S++ W+++AAHC+ R T +G S + + +++
Sbjct: 635 LGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRL 694
Query: 56 QKVIIHKDYKPPQLDSDLSLLLLATPVQFSNFKMPVCLQEEERTWDWCWMAQWVTTNGYD 115
+++I H + D D++LL L P ++S+ P+CL + + A WVT G+
Sbjct: 695 KRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFP-AGKAIWVTGWGHT 753
Query: 116 QYDDLN-MHLEKLRVVQISRKECAKRI-NQLSRNMIC-AWNEPGTNDCSSFPHSQGDSGA 172
QY + L+K + I++ C + Q++ M+C + G + C QGDSG
Sbjct: 754 QYGGTGALILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSGGVDSC------QGDSGG 807
Query: 173 PLVCAIYGTQRLFQVGVFSGGIRSGSRGRPGMFVSVAQF 211
PL ++ R+FQ GV S G R +PG++ + F
Sbjct: 808 PL-SSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLF 845
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,653,578
Number of Sequences: 37866
Number of extensions: 367437
Number of successful extensions: 1405
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 970
Number of HSP's gapped (non-prelim): 202
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.