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Search of human proteins with 16905073
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16905073 SoxLZ/Sox6 leucine zipper binding protein [Homo
sapiens]
(269 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16905073 SoxLZ/Sox6 leucine zipper binding protein [Homo sapi... 537 e-153
gi|50083279 centrosome protein 4 [Homo sapiens] 49 6e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 46 3e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 46 3e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 5e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 45 7e-05
gi|5901922 cell division cycle 37 protein [Homo sapiens] 44 1e-04
gi|34577114 cytomatrix protein p110 [Homo sapiens] 44 1e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 44 1e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens] 43 3e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 43 3e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens] 43 3e-04
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] 42 4e-04
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] 42 4e-04
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] 42 4e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 42 6e-04
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 42 6e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 42 6e-04
gi|156104908 myosin heavy chain 6 [Homo sapiens] 42 7e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 41 0.001
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 41 0.001
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 41 0.001
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 40 0.002
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 40 0.002
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 40 0.002
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 40 0.002
gi|4504063 golgin 97 [Homo sapiens] 40 0.002
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 40 0.002
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 40 0.003
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 40 0.003
>gi|16905073 SoxLZ/Sox6 leucine zipper binding protein [Homo
sapiens]
Length = 269
Score = 537 bits (1383), Expect = e-153
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 1 MNQEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLL 60
MNQEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLL
Sbjct: 1 MNQEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLL 60
Query: 61 IMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKE 120
IMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKE
Sbjct: 61 IMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKE 120
Query: 121 DLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTL 180
DLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTL
Sbjct: 121 DLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTL 180
Query: 181 GEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDVPHDPYVKISDSFWP 240
GEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDVPHDPYVKISDSFWP
Sbjct: 181 GEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDVPHDPYVKISDSFWP 240
Query: 241 PYVELLLRNGIALRHPEDPTRIRLEAFHQ 269
PYVELLLRNGIALRHPEDPTRIRLEAFHQ
Sbjct: 241 PYVELLLRNGIALRHPEDPTRIRLEAFHQ 269
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 48.5 bits (114), Expect = 6e-06
Identities = 45/172 (26%), Positives = 85/172 (49%), Gaps = 19/172 (11%)
Query: 9 DSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLT 68
D +++ +T +EL R E K ME+ Q+ + L LT +LS+L + +
Sbjct: 493 DYNSEIHQITRERDELQRMLERFEKYMEDIQSNVKL-----LTAERDKLSVLYNEAQ--- 544
Query: 69 AELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRW 128
ELS +K++ +T +++L ++E + DL +++ KE+ EKL+ E
Sbjct: 545 EELSALRKESTQT--TAPHNIVSLMEKEKELALSDLRRIMAEKEALREKLEHIEEVSLFG 602
Query: 129 LDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTL 180
E ++ +E L ++ +L+++ ELK+K+L +KE E L + L
Sbjct: 603 KSELEKTIEHLTCVNHQLESEK---------YELKSKVLIMKETIESLENKL 645
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 46.2 bits (108), Expect = 3e-05
Identities = 60/221 (27%), Positives = 102/221 (46%), Gaps = 23/221 (10%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTE---------TLTDSNAQLSLLIMQVKC 66
++T + +L EC E+ KD+++ + L+ + E LT+ A L I ++
Sbjct: 941 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 1000
Query: 67 LTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126
L + ++T + + ED + TL K + KL Q ++ + + E + +KL+ DLER +
Sbjct: 1001 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKI-KLEQQVDDLEGSLE-QEKKLRMDLERAK 1058
Query: 127 RWLD-----EQQQIMESLN---VLHSELKNKVETFS--ESRIFNELKTKMLNIKEYKEKL 176
R L+ Q+ IM+ N L +LK K S +S+I +E + K+ KE
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKE-- 1116
Query: 177 LSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
L E LE+ S K +K + S L + E LE
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Score = 35.8 bits (81), Expect = 0.040
Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 16/186 (8%)
Query: 26 RECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLT 85
++CEE ++E Q + +GTE NA L Q++ L E Q+ E LT
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESL-DQLETLKRENKNLQQ---EISDLT 1519
Query: 86 EDVLITLGK--EEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLH 143
E + GK E +K+++ +E ++ E+ + LE E+ + +I LN +
Sbjct: 1520 EQI-AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE---GKILRIQLELNQVK 1575
Query: 144 SELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQ 203
SE+ K+ E ++LK + I E + L D R KK + ++
Sbjct: 1576 SEVDRKIAEKDEE--IDQLKRNHIRIVESMQSTLDAEIRSRNDAI----RLKKKMEGDLN 1629
Query: 204 ESSVNL 209
E + L
Sbjct: 1630 EMEIQL 1635
Score = 29.6 bits (65), Expect = 2.9
Identities = 36/164 (21%), Positives = 72/164 (43%), Gaps = 17/164 (10%)
Query: 23 ELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETI 82
+L RE EE+ + +EE T + N + +++ E + + T T+
Sbjct: 1144 DLSRELEEISERLEEAGG-----ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATL 1198
Query: 83 PLTE-DVLITLGKE--EFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESL 139
D + LG++ Q+++Q LE S + + + L ++E + +++ +L
Sbjct: 1199 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTL 1258
Query: 140 NVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEF 183
SELK+K E + R+ N+L + + +L + GEF
Sbjct: 1259 EDQLSELKSKEE--EQQRLINDLTAQ-------RGRLQTESGEF 1293
Score = 28.9 bits (63), Expect = 4.9
Identities = 36/138 (26%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 85 TEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKL------KEDL----EREQRWLDEQQQ 134
TE + T+ KEEFQK++ +L + ++ EK+ K DL + E L + ++
Sbjct: 851 TEKEMATM-KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 135 IMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
+ L +L+ K++ +E E L K K KL E +D L
Sbjct: 910 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK--KRKLEDECSELKKDIDDLELTL 967
Query: 195 VK-KKKKNIQESSVNLIT 211
K +K+K+ E+ V +T
Sbjct: 968 AKVEKEKHATENKVKNLT 985
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 46.2 bits (108), Expect = 3e-05
Identities = 60/221 (27%), Positives = 102/221 (46%), Gaps = 23/221 (10%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTE---------TLTDSNAQLSLLIMQVKC 66
++T + +L EC E+ KD+++ + L+ + E LT+ A L I ++
Sbjct: 941 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 1000
Query: 67 LTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126
L + ++T + + ED + TL K + KL Q ++ + + E + +KL+ DLER +
Sbjct: 1001 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKI-KLEQQVDDLEGSLE-QEKKLRMDLERAK 1058
Query: 127 RWLD-----EQQQIMESLN---VLHSELKNKVETFS--ESRIFNELKTKMLNIKEYKEKL 176
R L+ Q+ IM+ N L +LK K S +S+I +E + K+ KE
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKE-- 1116
Query: 177 LSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
L E LE+ S K +K + S L + E LE
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Score = 35.8 bits (81), Expect = 0.040
Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 16/186 (8%)
Query: 26 RECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLT 85
++CEE ++E Q + +GTE NA L Q++ L E Q+ E LT
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESL-DQLETLKRENKNLQQ---EISDLT 1519
Query: 86 EDVLITLGK--EEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLH 143
E + GK E +K+++ +E ++ E+ + LE E+ + +I LN +
Sbjct: 1520 EQI-AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE---GKILRIQLELNQVK 1575
Query: 144 SELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQ 203
SE+ K+ E ++LK + I E + L D R KK + ++
Sbjct: 1576 SEVDRKIAEKDEE--IDQLKRNHIRIVESMQSTLDAEIRSRNDAI----RLKKKMEGDLN 1629
Query: 204 ESSVNL 209
E + L
Sbjct: 1630 EMEIQL 1635
Score = 29.6 bits (65), Expect = 2.9
Identities = 36/164 (21%), Positives = 72/164 (43%), Gaps = 17/164 (10%)
Query: 23 ELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETI 82
+L RE EE+ + +EE T + N + +++ E + + T T+
Sbjct: 1144 DLSRELEEISERLEEAGG-----ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATL 1198
Query: 83 PLTE-DVLITLGKE--EFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESL 139
D + LG++ Q+++Q LE S + + + L ++E + +++ +L
Sbjct: 1199 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTL 1258
Query: 140 NVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEF 183
SELK+K E + R+ N+L + + +L + GEF
Sbjct: 1259 EDQLSELKSKEE--EQQRLINDLTAQ-------RGRLQTESGEF 1293
Score = 28.9 bits (63), Expect = 4.9
Identities = 36/138 (26%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 85 TEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKL------KEDL----EREQRWLDEQQQ 134
TE + T+ KEEFQK++ +L + ++ EK+ K DL + E L + ++
Sbjct: 851 TEKEMATM-KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 135 IMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
+ L +L+ K++ +E E L K K KL E +D L
Sbjct: 910 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK--KRKLEDECSELKKDIDDLELTL 967
Query: 195 VK-KKKKNIQESSVNLIT 211
K +K+K+ E+ V +T
Sbjct: 968 AKVEKEKHATENKVKNLT 985
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 45.4 bits (106), Expect = 5e-05
Identities = 49/223 (21%), Positives = 102/223 (45%), Gaps = 37/223 (16%)
Query: 21 EEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLT--AELSQWQKK- 77
E+EL +E EE+ DMEE K + N + L+ + K L E WQ++
Sbjct: 1711 EKELAQELEELEWDMEELSWKEE--------ELNQEEGKLVEEKKKLAEEEEALAWQREK 1762
Query: 78 --TPETIPLTEDVLITLGKEEF----QKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDE 131
ET E+ L+ KE+ +K+ ++ E + +E EK + ++ +RW++
Sbjct: 1763 LSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINS 1822
Query: 132 QQQIMESLNVLH------------SELKNKVETFSESRIFNELKTKMLNIKEYKEKLLST 179
+++ ++ +L+ ++ K K+ E+ ++N K ++ + K+ ++ +
Sbjct: 1823 MEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYN--KERLTHSKKQLVQVKNK 1880
Query: 180 LGEF------LEDHFPLPDRSVKKKKKNIQESSVNLITLHEML 216
LG F +E+ +V KKK+ + E+ L+ + + L
Sbjct: 1881 LGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923
Score = 30.4 bits (67), Expect = 1.7
Identities = 46/203 (22%), Positives = 83/203 (40%), Gaps = 29/203 (14%)
Query: 3 QEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIM 62
QE L + + + EEE +RE EE K+ EE + K
Sbjct: 2240 QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK--------------------- 2278
Query: 63 QVKCLTAELSQWQK-KTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKED 121
QV+ E + +K K E + E+V KEE + + +E ++ L+E+
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEVFEE--KEEIMSEEETESLSDEEEEEESCSLEEE 2336
Query: 122 LEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLN---IKEYKEKLLS 178
++RE+ L +++Q + L+ + S R K + + +K +KL+S
Sbjct: 2337 VDREKEILKKEKQ-FKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMS 2395
Query: 179 TLGEFLE-DHFPLPDRSVKKKKK 200
T E E P+P++ + + K
Sbjct: 2396 TALEMKEKTPVPVPEKQISWEDK 2418
Score = 29.6 bits (65), Expect = 2.9
Identities = 36/156 (23%), Positives = 67/156 (42%), Gaps = 30/156 (19%)
Query: 95 EEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWL--------------------DEQQQ 134
EE + L +LE S + E+ +E+ ERE+ + +E+++
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Query: 135 IMESLNVLHSELKNKVETFSE-SRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDR 193
+ E++ K E F E I +E +T+ L+ +E +E+ S LE+
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCS-----LEEEVDREKE 2342
Query: 194 SVKKKKK-NIQESSVNLITLHEMLEILINRLFDVPH 228
+KK+K+ +QE + E +++ L VPH
Sbjct: 2343 ILKKEKQFKLQEQRRKSLRGRER---VLSILRGVPH 2375
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 45.1 bits (105), Expect = 7e-05
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 23/221 (10%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTE---------TLTDSNAQLSLLIMQVKC 66
++T + +L EC E+ KD+++ + L+ + E LT+ A L I ++
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 998
Query: 67 LTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126
L + ++T + + ED + TL K + KL Q ++ + + E + +K++ DLER +
Sbjct: 999 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKI-KLEQQVDDLEGSLE-QEKKIRMDLERAK 1056
Query: 127 RWLD-----EQQQIMESLN---VLHSELKNKVETFS--ESRIFNELKTKMLNIKEYKEKL 176
R L+ Q+ M+ N L +LK K S +S+I +E M K+ KE
Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKE-- 1114
Query: 177 LSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
L E LE+ S K +K + S L + E LE
Sbjct: 1115 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1155
Score = 29.3 bits (64), Expect = 3.8
Identities = 42/189 (22%), Positives = 81/189 (42%), Gaps = 24/189 (12%)
Query: 30 EMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVL 89
++ K ++E Q ++ + E + A + Q L+ EL + ++ E T
Sbjct: 1107 QLQKKIKELQARIEEL-EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS-AQ 1164
Query: 90 ITLGKE---EFQKLRQDLEMVL----STKESKNEKLKEDLEREQRWLDEQQQIMESLNVL 142
I + K+ EFQK+R+DLE +T + +K + + +D Q++ + L
Sbjct: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKE 1224
Query: 143 HSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNI 202
SE+K +++ +L + M + + K L + LED S K K+
Sbjct: 1225 KSEMKMEID---------DLASNMETVSKAKGN-LEKMCRALEDQL-----SEIKTKEEE 1269
Query: 203 QESSVNLIT 211
Q+ +N +T
Sbjct: 1270 QQRLINDLT 1278
>gi|5901922 cell division cycle 37 protein [Homo sapiens]
Length = 378
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 30/150 (20%)
Query: 21 EEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPE 80
+EEL R C E + + ECQ KL + E A+L L + + L E W++K E
Sbjct: 47 KEELDRGCRECKRKVAECQRKLKEL--EVAEGGKAELERLQAEAQQLRKEERSWEQKLEE 104
Query: 81 ------TIPLTEDVLITLGKEEF---------QKLRQDLEMVLSTKESKNEKLKEDLERE 125
++P D TL K+ F +K +D E V +E K++ E E++
Sbjct: 105 MRKKEKSMPWNVD---TLSKDGFSKSMVNTKPEKTEEDSEEV---REQKHKTFVEKYEKQ 158
Query: 126 -------QRWLDEQQQIMESLNVLHSELKN 148
+RW D Q+ + ++++++ E N
Sbjct: 159 IKHFGMLRRWDDSQKYLSDNVHLVCEETAN 188
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 43.9 bits (102), Expect = 1e-04
Identities = 51/211 (24%), Positives = 89/211 (42%), Gaps = 35/211 (16%)
Query: 11 TTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGT------ETLTDSNAQLSLLIMQV 64
T + D+T + L E +M +E + K++++ E L D + QL+ L +V
Sbjct: 510 TKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRV 569
Query: 65 KCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLER 124
K L + S T+ L TL E LS KE E+LKE ER
Sbjct: 570 KSLQTDSSN-----------TDTALATL------------EEALSEKERIIERLKEQRER 606
Query: 125 EQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFL 184
+ R E+ + +ES + +LK KV E ++ ++++KE+ L S G
Sbjct: 607 DDR---ERLEEIESFRKENKDLKEKVNALQAE--LTEKESSLIDLKEHASSLASA-GLKR 660
Query: 185 EDHFPLPDRSVKKKKKNIQESSVNLITLHEM 215
+ + ++++KK+ + L H +
Sbjct: 661 DSKLKSLEIAIEQKKEECSKLEAQLKKAHNI 691
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 43.9 bits (102), Expect = 1e-04
Identities = 58/221 (26%), Positives = 102/221 (46%), Gaps = 23/221 (10%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTE---------TLTDSNAQLSLLIMQVKC 66
++T + +L EC E+ KD+++ + L+ + E LT+ A L I ++
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 998
Query: 67 LTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126
L + ++T + + + ED + TL K + KL Q ++ + + E + +KL DLER +
Sbjct: 999 EKKALQEAHQQTLDDLQMEEDKVNTLTKAK-TKLEQQVDDLEGSLE-QEKKLCMDLERAK 1056
Query: 127 RWLD-----EQQQIMESLN---VLHSELKNKVETFS--ESRIFNELKTKMLNIKEYKEKL 176
R L+ Q+ M++ N L+ +LK K S + +I +E + K+ KE
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKE-- 1114
Query: 177 LSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
L E LE+ S K +K + S L + E LE
Sbjct: 1115 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1155
Score = 32.7 bits (73), Expect = 0.34
Identities = 45/194 (23%), Positives = 83/194 (42%), Gaps = 25/194 (12%)
Query: 30 EMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVL 89
++ K ++E Q ++ + E + A + Q L+ EL + ++ E T
Sbjct: 1107 QLQKKIKELQARIEEL-EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS-AQ 1164
Query: 90 ITLGKE---EFQKLRQDLEMVL----STKESKNEKLKEDLEREQRWLDEQQQIMESLNVL 142
I + K+ EFQK+R+DLE +T + +K + + +D Q++ + L
Sbjct: 1165 IEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKE 1224
Query: 143 HSELKNKVETFSESRIFNELKTKMLNIKEYK---EKLLSTLGEFLEDHFPLPDRSVKKKK 199
SELK ++ N+L + M + + K EK+ T LED ++++
Sbjct: 1225 KSELKMEI---------NDLASNMETVSKAKANFEKMCRT----LEDQLSEIKTKEEEQQ 1271
Query: 200 KNIQESSVNLITLH 213
+ I E S LH
Sbjct: 1272 RLINELSAQKARLH 1285
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.1 bits (100), Expect = 3e-04
Identities = 54/248 (21%), Positives = 112/248 (45%), Gaps = 34/248 (13%)
Query: 4 EDLDPDSTTDVGDVTNTEE--ELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSL-- 59
+DL V + EE ++I E + K +EE L+ E L +N + ++
Sbjct: 780 QDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEE------LLEAELLKVANKEKTVQD 833
Query: 60 LIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLK 119
L ++K L E+ Q + + + +T V +E Q L + E ++T ++ E+ +
Sbjct: 834 LKQEIKALKEEIGNVQLEKAQQLSITSKV------QELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 120 EDLEREQRWLDEQQQIMESLNVLHSEL-KNKVETFSESRIFNELKTKMLNIKEYKEKLLS 178
+DL +WL + Q+ ESL E+ ++ ++ S + F EL+ +L KE + K L
Sbjct: 888 KDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI-VLKEKENELKRLE 946
Query: 179 TLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDVPHDPYVKISDSF 238
+ +K+++ ++ + L + + ++ +++ + Y + S
Sbjct: 947 AM--------------LKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASS-- 990
Query: 239 WPPYVELL 246
+PP+ ELL
Sbjct: 991 FPPHEELL 998
Score = 41.2 bits (95), Expect = 0.001
Identities = 45/204 (22%), Positives = 96/204 (47%), Gaps = 18/204 (8%)
Query: 19 NTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKT 78
N EE L + +++ + E + ++ ++ ++A S+L ++ + AE + K+T
Sbjct: 562 NKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSA--SVLAEELHKVIAEKDKQIKQT 619
Query: 79 PETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIM-- 136
+++ D L + KEE K Q++ +L + K + L + L++ QQ +
Sbjct: 620 EDSLASERDRLTS--KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYV 677
Query: 137 --ESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
+ + +L +L++++ E F L + +K +KL + + E P++
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEE--FKILNDQNKALKSEVQKLQTLVSE-------QPNKD 728
Query: 195 V-KKKKKNIQESSVNLITLHEMLE 217
V ++ +K IQE L T+ E+LE
Sbjct: 729 VVEQMEKCIQEKDEKLKTVEELLE 752
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 43.1 bits (100), Expect = 3e-04
Identities = 54/248 (21%), Positives = 112/248 (45%), Gaps = 34/248 (13%)
Query: 4 EDLDPDSTTDVGDVTNTEE--ELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSL-- 59
+DL V + EE ++I E + K +EE L+ E L +N + ++
Sbjct: 780 QDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEE------LLEAELLKVANKEKTVQD 833
Query: 60 LIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLK 119
L ++K L E+ Q + + + +T V +E Q L + E ++T ++ E+ +
Sbjct: 834 LKQEIKALKEEIGNVQLEKAQQLSITSKV------QELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 120 EDLEREQRWLDEQQQIMESLNVLHSEL-KNKVETFSESRIFNELKTKMLNIKEYKEKLLS 178
+DL +WL + Q+ ESL E+ ++ ++ S + F EL+ +L KE + K L
Sbjct: 888 KDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI-VLKEKENELKRLE 946
Query: 179 TLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDVPHDPYVKISDSF 238
+ +K+++ ++ + L + + ++ +++ + Y + S
Sbjct: 947 AM--------------LKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASS-- 990
Query: 239 WPPYVELL 246
+PP+ ELL
Sbjct: 991 FPPHEELL 998
Score = 41.2 bits (95), Expect = 0.001
Identities = 45/204 (22%), Positives = 96/204 (47%), Gaps = 18/204 (8%)
Query: 19 NTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKT 78
N EE L + +++ + E + ++ ++ ++A S+L ++ + AE + K+T
Sbjct: 562 NKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSA--SVLAEELHKVIAEKDKQIKQT 619
Query: 79 PETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIM-- 136
+++ D L + KEE K Q++ +L + K + L + L++ QQ +
Sbjct: 620 EDSLASERDRLTS--KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYV 677
Query: 137 --ESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
+ + +L +L++++ E F L + +K +KL + + E P++
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEE--FKILNDQNKALKSEVQKLQTLVSE-------QPNKD 728
Query: 195 V-KKKKKNIQESSVNLITLHEMLE 217
V ++ +K IQE L T+ E+LE
Sbjct: 729 VVEQMEKCIQEKDEKLKTVEELLE 752
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.1 bits (100), Expect = 3e-04
Identities = 54/248 (21%), Positives = 112/248 (45%), Gaps = 34/248 (13%)
Query: 4 EDLDPDSTTDVGDVTNTEE--ELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSL-- 59
+DL V + EE ++I E + K +EE L+ E L +N + ++
Sbjct: 780 QDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEE------LLEAELLKVANKEKTVQD 833
Query: 60 LIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLK 119
L ++K L E+ Q + + + +T V +E Q L + E ++T ++ E+ +
Sbjct: 834 LKQEIKALKEEIGNVQLEKAQQLSITSKV------QELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 120 EDLEREQRWLDEQQQIMESLNVLHSEL-KNKVETFSESRIFNELKTKMLNIKEYKEKLLS 178
+DL +WL + Q+ ESL E+ ++ ++ S + F EL+ +L KE + K L
Sbjct: 888 KDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI-VLKEKENELKRLE 946
Query: 179 TLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDVPHDPYVKISDSF 238
+ +K+++ ++ + L + + ++ +++ + Y + S
Sbjct: 947 AM--------------LKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASS-- 990
Query: 239 WPPYVELL 246
+PP+ ELL
Sbjct: 991 FPPHEELL 998
Score = 41.2 bits (95), Expect = 0.001
Identities = 45/204 (22%), Positives = 96/204 (47%), Gaps = 18/204 (8%)
Query: 19 NTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKT 78
N EE L + +++ + E + ++ ++ ++A S+L ++ + AE + K+T
Sbjct: 562 NKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSA--SVLAEELHKVIAEKDKQIKQT 619
Query: 79 PETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIM-- 136
+++ D L + KEE K Q++ +L + K + L + L++ QQ +
Sbjct: 620 EDSLASERDRLTS--KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYV 677
Query: 137 --ESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
+ + +L +L++++ E F L + +K +KL + + E P++
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEE--FKILNDQNKALKSEVQKLQTLVSE-------QPNKD 728
Query: 195 V-KKKKKNIQESSVNLITLHEMLE 217
V ++ +K IQE L T+ E+LE
Sbjct: 729 VVEQMEKCIQEKDEKLKTVEELLE 752
>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 42.4 bits (98), Expect = 4e-04
Identities = 49/219 (22%), Positives = 95/219 (43%), Gaps = 30/219 (13%)
Query: 11 TTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAE 70
T + + NT E E + K++++ Q K+S I ET+T S A LS +++ L
Sbjct: 238 TAQINEFENTREVKRMETYQKKKELDKLQTKMSKI-KETVTVSAAVLSDHNLEIARLHES 296
Query: 71 LSQWQKKTPETIPLTEDVLITLGK--------------------EEFQKLRQDLEMVLST 110
+ W+++ E L +D+ I K E K++Q +E + +
Sbjct: 297 IRYWEQEVSE---LKKDLAILEAKLCFFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAA 353
Query: 111 K---ESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKML 167
+ + EK+K + + L E+++ +H E + ++ S+ F L K +
Sbjct: 354 RMEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYF--LSQKRV 411
Query: 168 NIKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQESS 206
+IK +E L+ TL E + + + +K N++ S
Sbjct: 412 DIKNMEEGLI-TLQELQQATKTVYQQQIKILSANLERES 449
Score = 31.6 bits (70), Expect = 0.76
Identities = 29/148 (19%), Positives = 65/148 (43%), Gaps = 36/148 (24%)
Query: 56 QLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKN 115
+++ + M++ E+ +KK + E LG+++ + R+ VLS ++
Sbjct: 131 EINTIKMRITRTENEIELLKKKITDLTKYNE----ALGEKQEELARKHARFVLSLNQTME 186
Query: 116 EKL----------------KEDLEREQRWLDEQQQIMES-----------LNVLHSELKN 148
+K +ED+ +++ + E +++ME L +E +N
Sbjct: 187 KKATTTVYINETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFEN 246
Query: 149 -----KVETFSESRIFNELKTKMLNIKE 171
++ET+ + + ++L+TKM IKE
Sbjct: 247 TREVKRMETYQKKKELDKLQTKMSKIKE 274
>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 42.4 bits (98), Expect = 4e-04
Identities = 49/219 (22%), Positives = 95/219 (43%), Gaps = 30/219 (13%)
Query: 11 TTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAE 70
T + + NT E E + K++++ Q K+S I ET+T S A LS +++ L
Sbjct: 238 TAQINEFENTREVKRMETYQKKKELDKLQTKMSKI-KETVTVSAAVLSDHNLEIARLHES 296
Query: 71 LSQWQKKTPETIPLTEDVLITLGK--------------------EEFQKLRQDLEMVLST 110
+ W+++ E L +D+ I K E K++Q +E + +
Sbjct: 297 IRYWEQEVSE---LKKDLAILEAKLCFFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAA 353
Query: 111 K---ESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKML 167
+ + EK+K + + L E+++ +H E + ++ S+ F L K +
Sbjct: 354 RMEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYF--LSQKRV 411
Query: 168 NIKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQESS 206
+IK +E L+ TL E + + + +K N++ S
Sbjct: 412 DIKNMEEGLI-TLQELQQATKTVYQQQIKILSANLERES 449
Score = 31.6 bits (70), Expect = 0.76
Identities = 29/148 (19%), Positives = 65/148 (43%), Gaps = 36/148 (24%)
Query: 56 QLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKN 115
+++ + M++ E+ +KK + E LG+++ + R+ VLS ++
Sbjct: 131 EINTIKMRITRTENEIELLKKKITDLTKYNE----ALGEKQEELARKHARFVLSLNQTME 186
Query: 116 EKL----------------KEDLEREQRWLDEQQQIMES-----------LNVLHSELKN 148
+K +ED+ +++ + E +++ME L +E +N
Sbjct: 187 KKATTTVYINETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFEN 246
Query: 149 -----KVETFSESRIFNELKTKMLNIKE 171
++ET+ + + ++L+TKM IKE
Sbjct: 247 TREVKRMETYQKKKELDKLQTKMSKIKE 274
>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 42.4 bits (98), Expect = 4e-04
Identities = 49/219 (22%), Positives = 95/219 (43%), Gaps = 30/219 (13%)
Query: 11 TTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAE 70
T + + NT E E + K++++ Q K+S I ET+T S A LS +++ L
Sbjct: 238 TAQINEFENTREVKRMETYQKKKELDKLQTKMSKI-KETVTVSAAVLSDHNLEIARLHES 296
Query: 71 LSQWQKKTPETIPLTEDVLITLGK--------------------EEFQKLRQDLEMVLST 110
+ W+++ E L +D+ I K E K++Q +E + +
Sbjct: 297 IRYWEQEVSE---LKKDLAILEAKLCFFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAA 353
Query: 111 K---ESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKML 167
+ + EK+K + + L E+++ +H E + ++ S+ F L K +
Sbjct: 354 RMEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYF--LSQKRV 411
Query: 168 NIKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQESS 206
+IK +E L+ TL E + + + +K N++ S
Sbjct: 412 DIKNMEEGLI-TLQELQQATKTVYQQQIKILSANLERES 449
Score = 31.6 bits (70), Expect = 0.76
Identities = 29/148 (19%), Positives = 65/148 (43%), Gaps = 36/148 (24%)
Query: 56 QLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKN 115
+++ + M++ E+ +KK + E LG+++ + R+ VLS ++
Sbjct: 131 EINTIKMRITRTENEIELLKKKITDLTKYNE----ALGEKQEELARKHARFVLSLNQTME 186
Query: 116 EKL----------------KEDLEREQRWLDEQQQIMES-----------LNVLHSELKN 148
+K +ED+ +++ + E +++ME L +E +N
Sbjct: 187 KKATTTVYINETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFEN 246
Query: 149 -----KVETFSESRIFNELKTKMLNIKE 171
++ET+ + + ++L+TKM IKE
Sbjct: 247 TREVKRMETYQKKKELDKLQTKMSKIKE 274
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 42.0 bits (97), Expect = 6e-04
Identities = 58/221 (26%), Positives = 102/221 (46%), Gaps = 23/221 (10%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSN------AQLSLLIMQVKCLTA 69
++T + +L EC E+ KD+++ + L+ + E N +LS L + LT
Sbjct: 936 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTR 995
Query: 70 E---LSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126
E L + ++ + + ED + +L K + KL Q +E + S+ E + +KL+ DLER +
Sbjct: 996 EKKALQEAHQQALDDLQAEEDKVNSLNKTK-SKLEQQVEDLESSLE-QEKKLRVDLERNK 1053
Query: 127 RWLD-----EQQQIMESLN---VLHSELKNKVETFS--ESRIFNELKTKMLNIKEYKEKL 176
R L+ Q+ I++ N L LK K + +S++ +E + K+ KE
Sbjct: 1054 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKE-- 1111
Query: 177 LSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
L E LE+ + K +K + + L L E LE
Sbjct: 1112 LQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLE 1152
Score = 28.5 bits (62), Expect = 6.4
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 24/143 (16%)
Query: 85 TEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKL------KEDLE-----REQRWLDEQQ 133
TE + T+ KEEFQK + +L + ++ EKL K DL+ + LD ++
Sbjct: 846 TEKEMATM-KEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEE 904
Query: 134 ---QIMESLNVLHSELKNKVETFSESRIFN-ELKTKMLNIKEYKEKLLSTLGEFLEDHFP 189
Q++++ L +++K E + N EL K K KL E +D
Sbjct: 905 RCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAK-------KRKLEDECSELKKDIDD 957
Query: 190 LPDRSVK-KKKKNIQESSVNLIT 211
L K +K+K+ E+ V +T
Sbjct: 958 LELTLAKVEKEKHATENKVKNLT 980
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 42.0 bits (97), Expect = 6e-04
Identities = 43/190 (22%), Positives = 92/190 (48%), Gaps = 26/190 (13%)
Query: 16 DVTNTEEELIRECEEMWKDMEEC---QNKLSL---IGTETLTDSNAQLSL-LIMQVKCLT 68
DV E+L+ CE++ +EEC N+LSL ETL ++ L K L
Sbjct: 674 DVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLL 733
Query: 69 AELSQWQKKTPE----------TIPLTEDVLITLGKE---EFQKLRQDLEMVLSTKESKN 115
E ++++K E + L + LI L ++ E +L++++E + + +
Sbjct: 734 EEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETK 793
Query: 116 EKLKEDLEREQ---RWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEY 172
+ L LE ++ + +++++ +E L S+L+ +++ +S++ NE+ + + E
Sbjct: 794 DVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTI---EE 850
Query: 173 KEKLLSTLGE 182
K++ L ++ E
Sbjct: 851 KDRSLGSMKE 860
Score = 36.6 bits (83), Expect = 0.024
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 12/156 (7%)
Query: 21 EEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPE 80
++ L+ E + K +EE N +L T L + L L + AEL + ++
Sbjct: 729 KKRLLEEANKYEKTIEELSNARNL-NTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDT 787
Query: 81 TIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLN 140
T+DVL + +E+ Q L +++ KE EKLKE + Q LD+ Q +
Sbjct: 788 DHKETKDVLSSSLEEQKQ-----LTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNE 842
Query: 141 VLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKL 176
+L ++ K R +K + +++E E+L
Sbjct: 843 ILRQTIEEK------DRSLGSMKEENNHLQEELERL 872
Score = 33.5 bits (75), Expect = 0.20
Identities = 46/177 (25%), Positives = 81/177 (45%), Gaps = 20/177 (11%)
Query: 17 VTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQK 76
++ + E L +E EE+ K ++E + TL ++N +LS I L + +
Sbjct: 1338 LSESSELLQQELEELRKSLQEKDATI-----RTLQENNHRLSDSIAATSELERKEHEQTD 1392
Query: 77 KTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKED--LEREQRWLDEQQQ 134
+ + +DVL L KE+ ++ + +LS+ E+ K+ E+ L + L E+
Sbjct: 1393 SEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERIL 1452
Query: 135 IME-SLNVLHSELKNKVETF----SESRIFNELKTK---MLNIKEY-----KEKLLS 178
I+E + L E + VET+ +E + E K ML KE+ KEK L+
Sbjct: 1453 ILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALA 1509
Score = 33.5 bits (75), Expect = 0.20
Identities = 42/169 (24%), Positives = 74/169 (43%), Gaps = 18/169 (10%)
Query: 17 VTNTEEELIRECEEMWK-------DMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTA 69
VT EE+L+ M +E Q +L+++ + ++ QLS+ QVK
Sbjct: 1613 VTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQR-DETALQLSVSQEQVKQYAL 1671
Query: 70 ELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWL 129
L+ Q E E + + E+ ++L + + E K L+E L+ L
Sbjct: 1672 SLANLQMVL-EHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAAL 1730
Query: 130 DEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLS 178
D ++ E L+V K E E + NEL+ +ML+ + ++KL+S
Sbjct: 1731 DSASRLTEQLDV-------KEEQIEELKRQNELRQEMLD--DVQKKLMS 1770
Score = 32.7 bits (73), Expect = 0.34
Identities = 46/229 (20%), Positives = 90/229 (39%), Gaps = 54/229 (23%)
Query: 1 MNQEDLDPDSTTDV-----------GDVTNTEEELIRECEEMWKDMEECQNKLSL----- 44
+ Q D D T DV + N +E I + +E ++E +K S
Sbjct: 782 IEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKN 841
Query: 45 -IGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTE----DVLITLGKE--EF 97
I +T+ + + L + + L EL + +++ T P+ + D + L E +
Sbjct: 842 EILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQL 901
Query: 98 QKLRQDLE-------MVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHS------ 144
+++ LE ++ + +L + L+ +++ +DE + E +N H+
Sbjct: 902 NTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEK 961
Query: 145 --ELKNKVETFSE----------------SRIFNELKTKMLNIKEYKEK 175
E+K+ +T + S IF E K + LNI+ EK
Sbjct: 962 DEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEK 1010
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 42.0 bits (97), Expect = 6e-04
Identities = 55/228 (24%), Positives = 98/228 (42%), Gaps = 37/228 (16%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTE---------TLTDSNAQLSLLIMQVKC 66
++T + +L EC E+ KD+++ + L+ + E LT+ A L I ++
Sbjct: 938 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSK 997
Query: 67 LTAELSQWQKKTPETIPLTEDV--LITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLER 124
L + ++T + + ED ++T K + ++ DLE L + +KL+ DLER
Sbjct: 998 EKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSL----EQEKKLRMDLER 1053
Query: 125 EQRWLD---------------EQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNI 169
+R L+ ++QQ+ E L E+ N + S+I +E ++
Sbjct: 1054 AKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLI-----SKIEDEQAVEIQLQ 1108
Query: 170 KEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
K+ KE L E L + S K +K + S L + E LE
Sbjct: 1109 KKIKE--LQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLE 1154
Score = 33.5 bits (75), Expect = 0.20
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 10/147 (6%)
Query: 17 VTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQK 76
++ E+E E + + K ++E Q ++ +G E + A + Q L+ EL + +
Sbjct: 1094 ISKIEDEQAVEIQ-LQKKIKELQARIEELGEE-IEAERASRAKAEKQRSDLSRELEEISE 1151
Query: 77 KTPETIPLTEDVLITLGKE---EFQKLRQDLEMVLSTKESK----NEKLKEDLEREQRWL 129
+ E T + L K+ EFQKLR+DLE E+ +K + + +
Sbjct: 1152 RLEEAGGATS-AQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQI 1210
Query: 130 DEQQQIMESLNVLHSELKNKVETFSES 156
D Q++ + L SELK + + S +
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETDDLSSN 1237
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 41.6 bits (96), Expect = 7e-04
Identities = 51/219 (23%), Positives = 104/219 (47%), Gaps = 19/219 (8%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTE---------TLTDSNAQLSLLIMQVKC 66
++T + +L EC E+ KD+++ + L+ + E LT+ A L +I ++
Sbjct: 937 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTK 996
Query: 67 LTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126
L + ++ + + + ED + +L K + KL Q ++ + + E + +K++ DLER +
Sbjct: 997 EKKALQEAHQQALDDLQVEEDKVNSLSKSKV-KLEQQVDDLEGSLE-QEKKVRMDLERAK 1054
Query: 127 RWLD-----EQQQIMESLN-VLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTL 180
R L+ Q+ IM+ N L E K K + F ++ ++++ + + + ++KL
Sbjct: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114
Query: 181 G--EFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
E LE+ + K +K + S L + E LE
Sbjct: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1153
Score = 29.3 bits (64), Expect = 3.8
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 14/138 (10%)
Query: 85 TEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKL------KEDL----EREQRWLDEQQQ 134
TE + T+ KEEF ++++ LE + ++ EK+ K DL + EQ L++ ++
Sbjct: 847 TEKEMATM-KEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 135 IMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
+ L +L+ KV+ +E E L K K KL E +D L
Sbjct: 906 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKKDIDDLELTL 963
Query: 195 VK-KKKKNIQESSVNLIT 211
K +K+K+ E+ V +T
Sbjct: 964 AKVEKEKHATENKVKNLT 981
Score = 28.9 bits (63), Expect = 4.9
Identities = 46/205 (22%), Positives = 92/205 (44%), Gaps = 17/205 (8%)
Query: 30 EMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVL 89
++ K ++E Q ++ + E + A+ + ++ L+ EL + ++ E T V
Sbjct: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSD-LSRELEEISERLEEAGGATS-VQ 1162
Query: 90 ITLGKE---EFQKLRQDLEMVL----STKESKNEKLKEDLEREQRWLDEQQQIMESLNVL 142
I + K+ EFQK+R+DLE +T + +K + + +D Q++ + L
Sbjct: 1163 IEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1222
Query: 143 HSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFL----EDHFPLPDRSVKKK 198
SE K +++ + S + +K K N+++ L E+ E L D + ++
Sbjct: 1223 KSEFKLELDDVT-SNMEQIIKAK-ANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRA 1280
Query: 199 KKNIQESSVNLITLHEMLEILINRL 223
K +Q + L E E LI++L
Sbjct: 1281 K--LQTENGELARQLEEKEALISQL 1303
Score = 28.9 bits (63), Expect = 4.9
Identities = 54/232 (23%), Positives = 94/232 (40%), Gaps = 23/232 (9%)
Query: 3 QEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIM 62
QE++ D T +G+ EL + +++ + E Q+ L A+ SL
Sbjct: 1508 QEEIS-DLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALE----------EAEASLEHE 1556
Query: 63 QVKCLTAELSQWQKKTPETIPLTE-DVLITLGKEEFQKLRQDLEMVLSTK-ESKNE---- 116
+ K L A+L Q K L E D + K Q++ L+ L + S+NE
Sbjct: 1557 EGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRV 1616
Query: 117 --KLKEDLEREQRWLDEQQQI----MESLNVLHSELKNKVETFSESRIFNELKTKMLNIK 170
K++ DL + L ++ + + L S LK+ ++ N+ + + I
Sbjct: 1617 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1676
Query: 171 EYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINR 222
E + LL E L +RS K ++ + E+S + LH LIN+
Sbjct: 1677 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1728
Score = 28.1 bits (61), Expect = 8.4
Identities = 36/170 (21%), Positives = 69/170 (40%), Gaps = 29/170 (17%)
Query: 18 TNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKK 77
T E + I+ EE+ EE + KL+ + L D+ V+ + A+ S +K
Sbjct: 1375 TKYETDAIQRTEEL----EEAKKKLA----QRLQDAEEA-------VEAVNAKCSSLEKT 1419
Query: 78 TPETIPLTEDVLITLGKEE-----FQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQ 132
ED+++ + + K +++ + +L+ + K E+ + +LE Q+
Sbjct: 1420 KHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSL 1479
Query: 133 QQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGE 182
+ L + E +ETF K + N++E L LGE
Sbjct: 1480 STELFKLKNAYEESLEHLETF---------KRENKNLQEEISDLTEQLGE 1520
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/204 (23%), Positives = 85/204 (41%), Gaps = 18/204 (8%)
Query: 11 TTDVGDVTNTEEELIRECEEMWKDMEECQNK-LSLIG-TETLTDSNAQLSLLIMQVKCLT 68
TT + VT ++ C ++ ++E + K LSL TE L +L ++VK
Sbjct: 687 TTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASK 746
Query: 69 AEL-----SQWQKKTPETIPLTE-DVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDL 122
+ Q Q T + TE + + KE R DL+ ES +KL +
Sbjct: 747 EQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQE 806
Query: 123 EREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGE 182
E +Q + + + + + H EL N+++T T++ +K KE L++ L
Sbjct: 807 EEKQILKQDFETLSQETKIQHEELNNRIQT---------TVTELQKVKMEKEALMTELST 857
Query: 183 FLEDHFPLPDRSVKKKKKNIQESS 206
++D S+K K ++ +
Sbjct: 858 -VKDKLSKVSDSLKNSKSEFEKEN 880
Score = 33.9 bits (76), Expect = 0.15
Identities = 44/209 (21%), Positives = 94/209 (44%), Gaps = 13/209 (6%)
Query: 3 QEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIM 62
Q+ L +T + + N E+++R+ + KD ++ QN +L L S +SLL
Sbjct: 493 QQALQQSTTAKLREAQNDLEQVLRQIGD--KD-QKIQNLEAL-----LQKSKENISLLEK 544
Query: 63 QVKCLTAELSQWQKKTPETIPLTED--VLITLGKEEFQKLRQDLEMVLSTKESKNEKLKE 120
+ + L A++ + +T L E L + +KL+ E +E+ +++++E
Sbjct: 545 EREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQE 604
Query: 121 DLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTL 180
+ D + S+N L+S+L E S+ I + KT++L E + +
Sbjct: 605 QKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAK---TAQ 661
Query: 181 GEFLEDHFPLPDRSVKKKKKNIQESSVNL 209
L++H +++ K++ + + + L
Sbjct: 662 RADLQNHLDTAQNALQDKQQELNKITTQL 690
Score = 32.7 bits (73), Expect = 0.34
Identities = 39/181 (21%), Positives = 81/181 (44%), Gaps = 26/181 (14%)
Query: 2 NQEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLI 61
NQ L + T + + ++ +E K +++ Q + SL E + + + I
Sbjct: 1072 NQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAE--I 1129
Query: 62 MQVKC--------LTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKES 113
++KC L EL + ++ + I +D L ++Q LE+ +
Sbjct: 1130 EEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLL-------IQQKLEL-----QG 1177
Query: 114 KNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYK 173
K + LK +E+E+R QQ + + + ELK + E+++ +E+K K + +K+++
Sbjct: 1178 KADSLKAAVEQEKR---NQQILKDQVKKEEEELKKEFIE-KEAKLHSEIKEKEVGMKKHE 1233
Query: 174 E 174
E
Sbjct: 1234 E 1234
Score = 29.3 bits (64), Expect = 3.8
Identities = 42/219 (19%), Positives = 88/219 (40%), Gaps = 37/219 (16%)
Query: 2 NQEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLI 61
NQ + + ++ D ++ +R ++ +E N+L+ L +S ++S L
Sbjct: 586 NQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELN----SQLNESKEKVSQLD 641
Query: 62 MQVKCLTAEL-SQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKE 120
+Q+K T L S KT + R DL+ L T ++ + ++
Sbjct: 642 IQIKAKTELLLSAEAAKTAQ--------------------RADLQNHLDTAQNALQDKQQ 681
Query: 121 DLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTK------------MLN 168
+L + LD+ ++ S+L++ ++ + E + E KT+ L
Sbjct: 682 ELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLE 741
Query: 169 IKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQESSV 207
+K KE+ L L + + + L R+ + K+ E +
Sbjct: 742 VKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Score = 28.5 bits (62), Expect = 6.4
Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 9/88 (10%)
Query: 90 ITLGKEEFQKLRQDLE-MVLSTKESK--NEKLKEDLEREQRWLDEQQQIMESLNVLHSEL 146
+ L +++ LRQ+++ + S KE K +E+LK++LE+ Q L +Q+ + L
Sbjct: 78 LALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQ-GLQQQEAKPDGL-----VT 131
Query: 147 KNKVETFSESRIFNELKTKMLNIKEYKE 174
+ E S + E +T+ NIK+ K+
Sbjct: 132 DSSAELQSLEQQLEEAQTENFNIKQMKD 159
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/224 (24%), Positives = 102/224 (45%), Gaps = 26/224 (11%)
Query: 9 DSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNA-QLSLLIMQVKCL 67
D T++ + ++E+ ++ E + E Q KL L T + +L ++VK
Sbjct: 3145 DRATELQEQLSSEKMVVAELKS-----ELAQTKLELETTLKAQHKHLKELEAFRLEVKDK 3199
Query: 68 TAE-------LSQWQKKTPETIPLTEDVLITLGKEEFQKLR--QDLEMVLSTKESKNEKL 118
T E L+ QKK+ E E LG+ E + +DL+ L +++ +N +L
Sbjct: 3200 TDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQL 3259
Query: 119 KEDLEREQRWLDEQQQIMESLNVLHS---------ELKNKVETFSESRIFNELKTKMLNI 169
LE++++ L+E QQ +ES +L+ L+ +V SE E+ + +
Sbjct: 3260 NLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRE 3319
Query: 170 KEYKEKLLSTLGEFLEDHFPLPDRS-VKKKKKNIQESSVNLITL 212
+E +L S+ G + PLP +K+ +K ++E ++ L
Sbjct: 3320 RELHAQLQSSDGTG-QSRPPLPSEDLLKELQKQLEEKHSRIVEL 3362
Score = 38.9 bits (89), Expect = 0.005
Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 26/190 (13%)
Query: 11 TTDVGDVTNTEEELIRECEE--MWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLT 68
T ++ D T ++L+ E +E + K+ E KL L ++ +++ ++K L
Sbjct: 345 TLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSE------EIKQLM 398
Query: 69 AELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRW 128
+ + QK+ + D++ + +E +KL Q + E +++ ++ +Q
Sbjct: 399 GTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQ---LRAELDEMYGQQI---VQMKQEL 452
Query: 129 LDEQQQIMESLNVLHS-ELKNKVETFSESRI-----------FNELKTKMLNIKEYKEKL 176
+ + ME + H E++N + ++S + NEL K+ + KEKL
Sbjct: 453 IRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKL 512
Query: 177 LSTLGEFLED 186
LG LE+
Sbjct: 513 KEELGLILEE 522
Score = 37.7 bits (86), Expect = 0.011
Identities = 49/220 (22%), Positives = 95/220 (43%), Gaps = 47/220 (21%)
Query: 27 ECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTE 86
E EE+ +++EE + G + L + A + + LTA L Q +++ ET + E
Sbjct: 170 EIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDET--MRE 227
Query: 87 DVLITLGKEEFQKLRQDLEMVLSTKESKNE----------KLKEDLEREQRWLDEQQQIM 136
+ +T E+ QKL+ + + +++ +N + K+ + Q+ L+EQ ++
Sbjct: 228 FLELT---EQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLL 284
Query: 137 ES-----------LNVLHSELK-------------NKVETFSESRIFNELKTKMLNIK-- 170
E ++ L ++K NK E + I EL TK++ +
Sbjct: 285 EDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKK 344
Query: 171 --EYKEKLLST---LGEFLEDHFPLPDRSVKKKKKNIQES 205
E K+KL + LGE L++ ++ +K K + S
Sbjct: 345 TLELKDKLTTADKLLGE-LQEQIVQKNQEIKNMKLELTNS 383
Score = 33.9 bits (76), Expect = 0.15
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 27/210 (12%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQ 75
++TN EE+L + EE+ EE Q +L + +S +L L + K ++ +
Sbjct: 2204 EITNLEEQLEQFREELENKNEEVQ-QLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLG 2262
Query: 76 KKTPETIPL-TEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQ 134
E+ + T+D + GK F ++ Q+ E+ + + KL++ L+ + +
Sbjct: 2263 LAIKESDAMSTQDQHVLFGK--FAQIIQEKEVEIDQLNEQVTKLQQQLK-----ITTDNK 2315
Query: 135 IMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
++E N L +L+ ++E L + +K +E+ + L E +E
Sbjct: 2316 VIEEKNELIRDLETQIEC---------LMSDQECVKRNREEEIEQLNEVIE--------K 2358
Query: 195 VKKKKKNI-QESSVNLITLHEMLEILINRL 223
++++ NI Q++S+N +L E + L ++L
Sbjct: 2359 LQQELANIGQKTSMNAHSLSEEADSLKHQL 2388
Score = 32.7 bits (73), Expect = 0.34
Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 14/98 (14%)
Query: 96 EFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQ------IMESLNVLHSELKNK 149
E ++LR L L + E + KLKEDLE E R E+ + + ++ L +E+ K
Sbjct: 621 ELERLRTQL---LFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQK 677
Query: 150 VET--FSESRIF---NELKTKMLNIKEYKEKLLSTLGE 182
+ET F + + N+L ++ +K+ ++ L+++ E
Sbjct: 678 IETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Score = 30.8 bits (68), Expect = 1.3
Identities = 39/214 (18%), Positives = 97/214 (45%), Gaps = 14/214 (6%)
Query: 17 VTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQK 76
+ + E+ ++ E M + + K + + E + Q SL+ + + +T ++++ QK
Sbjct: 667 IDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQK 726
Query: 77 KTPETIPLTEDVLITLGKE--EFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQ 134
+ E + E TL +E E Q + LE + KE+ ++ LE E L ++++
Sbjct: 727 EI-EILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKK 785
Query: 135 IMESLNVLHSELK--------NKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLE- 185
+E + +H+ + + +++ S+ ++ + ++ E ++ L E +E
Sbjct: 786 TLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEK 845
Query: 186 --DHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
+ F +++ + + +QE L+ + + LE
Sbjct: 846 QRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLE 879
Score = 29.6 bits (65), Expect = 2.9
Identities = 22/112 (19%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 21 EEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPE 80
E++ I+E E+ +E + + L +L ++V+C ++ +K +
Sbjct: 1965 EQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVK 2024
Query: 81 TIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQ 132
+ + + ++ F +L Q+ L +N+ L++ LE+ +++LDEQ
Sbjct: 2025 ALEIDVEEQVS----RFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQ 2072
Score = 29.3 bits (64), Expect = 3.8
Identities = 50/230 (21%), Positives = 93/230 (40%), Gaps = 41/230 (17%)
Query: 29 EEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDV 88
E+ K M N+L++ L D+N+Q L ++ + E Q++ + L E+
Sbjct: 485 EDQIKLMNVAINELNI----KLQDTNSQKEKLKEELGLILEEKCALQRQLED---LVEE- 536
Query: 89 LITLGKEEFQKLRQDLEMVLSTKESKNEKLK--EDLEREQRWLDEQQQIME--------- 137
++ +E+ Q+ RQ + S ++ L EDL+ E E ++ +E
Sbjct: 537 -LSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTN 595
Query: 138 ---SLNVLHSELKNKVETFSESRI--FNELKTKMLNIKEYK----------------EKL 176
L +L E ++ +ES+ L+T++L E + EKL
Sbjct: 596 YKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKL 655
Query: 177 LSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDV 226
LG + + +K + +Q NLIT L + I++L D+
Sbjct: 656 KDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDL 705
Score = 28.9 bits (63), Expect = 4.9
Identities = 40/175 (22%), Positives = 71/175 (40%), Gaps = 32/175 (18%)
Query: 40 NKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQK 99
NK+ E + D Q+ L+ +C+ ++ E I +V+ +K
Sbjct: 2314 NKVIEEKNELIRDLETQIECLMSDQECV-------KRNREEEIEQLNEVI--------EK 2358
Query: 100 LRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIF 159
L+Q+L + L E+ + + LD I E L L+ +VET +E F
Sbjct: 2359 LQQELANIGQKTSMNAHSLSEEADSLKHQLD--VVIAEKL-----ALEQQVETANEEMTF 2411
Query: 160 NELKTKMLNIKEYKEKLLSTLGEFLEDHFPLP-DRSVKKKKKNIQESSVNLITLH 213
+ K N K + + ++ F L +R +K ++I E+SVN+ H
Sbjct: 2412 MKNVLKETNFK---------MNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 2457
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/224 (24%), Positives = 102/224 (45%), Gaps = 26/224 (11%)
Query: 9 DSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNA-QLSLLIMQVKCL 67
D T++ + ++E+ ++ E + E Q KL L T + +L ++VK
Sbjct: 3137 DRATELQEQLSSEKMVVAELKS-----ELAQTKLELETTLKAQHKHLKELEAFRLEVKDK 3191
Query: 68 TAE-------LSQWQKKTPETIPLTEDVLITLGKEEFQKLR--QDLEMVLSTKESKNEKL 118
T E L+ QKK+ E E LG+ E + +DL+ L +++ +N +L
Sbjct: 3192 TDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQL 3251
Query: 119 KEDLEREQRWLDEQQQIMESLNVLHS---------ELKNKVETFSESRIFNELKTKMLNI 169
LE++++ L+E QQ +ES +L+ L+ +V SE E+ + +
Sbjct: 3252 NLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRE 3311
Query: 170 KEYKEKLLSTLGEFLEDHFPLPDRS-VKKKKKNIQESSVNLITL 212
+E +L S+ G + PLP +K+ +K ++E ++ L
Sbjct: 3312 RELHAQLQSSDGTG-QSRPPLPSEDLLKELQKQLEEKHSRIVEL 3354
Score = 38.9 bits (89), Expect = 0.005
Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 26/190 (13%)
Query: 11 TTDVGDVTNTEEELIRECEE--MWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLT 68
T ++ D T ++L+ E +E + K+ E KL L ++ +++ ++K L
Sbjct: 345 TLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSE------EIKQLM 398
Query: 69 AELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRW 128
+ + QK+ + D++ + +E +KL Q + E +++ ++ +Q
Sbjct: 399 GTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQ---LRAELDEMYGQQI---VQMKQEL 452
Query: 129 LDEQQQIMESLNVLHS-ELKNKVETFSESRI-----------FNELKTKMLNIKEYKEKL 176
+ + ME + H E++N + ++S + NEL K+ + KEKL
Sbjct: 453 IRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKL 512
Query: 177 LSTLGEFLED 186
LG LE+
Sbjct: 513 KEELGLILEE 522
Score = 37.7 bits (86), Expect = 0.011
Identities = 49/220 (22%), Positives = 95/220 (43%), Gaps = 47/220 (21%)
Query: 27 ECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTE 86
E EE+ +++EE + G + L + A + + LTA L Q +++ ET + E
Sbjct: 170 EIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDET--MRE 227
Query: 87 DVLITLGKEEFQKLRQDLEMVLSTKESKNE----------KLKEDLEREQRWLDEQQQIM 136
+ +T E+ QKL+ + + +++ +N + K+ + Q+ L+EQ ++
Sbjct: 228 FLELT---EQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLL 284
Query: 137 ES-----------LNVLHSELK-------------NKVETFSESRIFNELKTKMLNIK-- 170
E ++ L ++K NK E + I EL TK++ +
Sbjct: 285 EDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKK 344
Query: 171 --EYKEKLLST---LGEFLEDHFPLPDRSVKKKKKNIQES 205
E K+KL + LGE L++ ++ +K K + S
Sbjct: 345 TLELKDKLTTADKLLGE-LQEQIVQKNQEIKNMKLELTNS 383
Score = 33.9 bits (76), Expect = 0.15
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 27/210 (12%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQ 75
++TN EE+L + EE+ EE Q +L + +S +L L + K ++ +
Sbjct: 2196 EITNLEEQLEQFREELENKNEEVQ-QLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLG 2254
Query: 76 KKTPETIPL-TEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQ 134
E+ + T+D + GK F ++ Q+ E+ + + KL++ L+ + +
Sbjct: 2255 LAIKESDAMSTQDQHVLFGK--FAQIIQEKEVEIDQLNEQVTKLQQQLK-----ITTDNK 2307
Query: 135 IMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRS 194
++E N L +L+ ++E L + +K +E+ + L E +E
Sbjct: 2308 VIEEKNELIRDLETQIEC---------LMSDQECVKRNREEEIEQLNEVIE--------K 2350
Query: 195 VKKKKKNI-QESSVNLITLHEMLEILINRL 223
++++ NI Q++S+N +L E + L ++L
Sbjct: 2351 LQQELANIGQKTSMNAHSLSEEADSLKHQL 2380
Score = 32.7 bits (73), Expect = 0.34
Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 14/98 (14%)
Query: 96 EFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQ------IMESLNVLHSELKNK 149
E ++LR L L + E + KLKEDLE E R E+ + + ++ L +E+ K
Sbjct: 621 ELERLRTQL---LFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQK 677
Query: 150 VET--FSESRIF---NELKTKMLNIKEYKEKLLSTLGE 182
+ET F + + N+L ++ +K+ ++ L+++ E
Sbjct: 678 IETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Score = 30.8 bits (68), Expect = 1.3
Identities = 39/214 (18%), Positives = 97/214 (45%), Gaps = 14/214 (6%)
Query: 17 VTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQK 76
+ + E+ ++ E M + + K + + E + Q SL+ + + +T ++++ QK
Sbjct: 667 IDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQK 726
Query: 77 KTPETIPLTEDVLITLGKE--EFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQ 134
+ E + E TL +E E Q + LE + KE+ ++ LE E L ++++
Sbjct: 727 EI-EILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKK 785
Query: 135 IMESLNVLHSELK--------NKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLE- 185
+E + +H+ + + +++ S+ ++ + ++ E ++ L E +E
Sbjct: 786 TLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEK 845
Query: 186 --DHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
+ F +++ + + +QE L+ + + LE
Sbjct: 846 QRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLE 879
Score = 29.6 bits (65), Expect = 2.9
Identities = 22/112 (19%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 21 EEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPE 80
E++ I+E E+ +E + + L +L ++V+C ++ +K +
Sbjct: 1965 EQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVK 2024
Query: 81 TIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQ 132
+ + + ++ F +L Q+ L +N+ L++ LE+ +++LDEQ
Sbjct: 2025 ALEIDVEEQVS----RFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQ 2072
Score = 29.3 bits (64), Expect = 3.8
Identities = 50/230 (21%), Positives = 93/230 (40%), Gaps = 41/230 (17%)
Query: 29 EEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDV 88
E+ K M N+L++ L D+N+Q L ++ + E Q++ + L E+
Sbjct: 485 EDQIKLMNVAINELNI----KLQDTNSQKEKLKEELGLILEEKCALQRQLED---LVEE- 536
Query: 89 LITLGKEEFQKLRQDLEMVLSTKESKNEKLK--EDLEREQRWLDEQQQIME--------- 137
++ +E+ Q+ RQ + S ++ L EDL+ E E ++ +E
Sbjct: 537 -LSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTN 595
Query: 138 ---SLNVLHSELKNKVETFSESRI--FNELKTKMLNIKEYK----------------EKL 176
L +L E ++ +ES+ L+T++L E + EKL
Sbjct: 596 YKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKL 655
Query: 177 LSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDV 226
LG + + +K + +Q NLIT L + I++L D+
Sbjct: 656 KDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDL 705
Score = 28.9 bits (63), Expect = 4.9
Identities = 40/175 (22%), Positives = 71/175 (40%), Gaps = 32/175 (18%)
Query: 40 NKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQK 99
NK+ E + D Q+ L+ +C+ ++ E I +V+ +K
Sbjct: 2306 NKVIEEKNELIRDLETQIECLMSDQECV-------KRNREEEIEQLNEVI--------EK 2350
Query: 100 LRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIF 159
L+Q+L + L E+ + + LD I E L L+ +VET +E F
Sbjct: 2351 LQQELANIGQKTSMNAHSLSEEADSLKHQLD--VVIAEKL-----ALEQQVETANEEMTF 2403
Query: 160 NELKTKMLNIKEYKEKLLSTLGEFLEDHFPLP-DRSVKKKKKNIQESSVNLITLH 213
+ K N K + + ++ F L +R +K ++I E+SVN+ H
Sbjct: 2404 MKNVLKETNFK---------MNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 2449
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 17/145 (11%)
Query: 73 QWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQ 132
QW + + PL + +T +EE Q +L+ TKE + + E E EQ+
Sbjct: 833 QWWRLFTKVKPLLQ---VTRQEEEMQAKEDELQ---KTKERQQKAENELKELEQK----H 882
Query: 133 QQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPD 192
Q+ E N+L +L+ + E ++E+ E++ ++ K+ E++L + LE+
Sbjct: 883 SQLTEEKNLLQEQLQAETELYAEA---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 939
Query: 193 RSVKKKKKNIQESSVNLITLHEMLE 217
+ ++KK Q+ ++ L E LE
Sbjct: 940 QLQAERKKMAQQ----MLDLEEQLE 960
Score = 33.5 bits (75), Expect = 0.20
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 33 KDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITL 92
+ +EE +N L + L + L + L +LS +KK + E +
Sbjct: 1339 RQLEEERNSLQ----DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE--ALEE 1392
Query: 93 GKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVET 152
GK+ FQK ++L K + +KL++ R Q+ LD+ +++ L S L+ K
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1452
Query: 153 FSE 155
F +
Sbjct: 1453 FDQ 1455
Score = 32.3 bits (72), Expect = 0.44
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 16/150 (10%)
Query: 19 NTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVK-------CLTAEL 71
+ ++L R+ +E+ + E + + T+ A+++ L QV+ T L
Sbjct: 1785 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1844
Query: 72 SQWQKKTPETIPLTEDV--LITLGKEEFQKLR---QDLEMVLSTKESKNEKLKEDLEREQ 126
Q KK E + ED + KE+ +K + L+ L E +++++ + + Q
Sbjct: 1845 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1904
Query: 127 RWLDEQQQIMESL----NVLHSELKNKVET 152
R LDE + E++ N L S+L+ ET
Sbjct: 1905 RELDEATESNEAMGREVNALKSKLRRGNET 1934
Score = 32.0 bits (71), Expect = 0.58
Identities = 46/212 (21%), Positives = 89/212 (41%), Gaps = 20/212 (9%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTET--LTDSNAQLSLLIMQVKCLTAELSQ 73
+ +EEL R + + +ME+ + +G L S L + ++K EL
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE- 1552
Query: 74 WQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQ 133
+ + TED + L + Q L+ E L ++ +NE+ + L+R+ + +
Sbjct: 1553 ------DELQATEDAKLRL-EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Query: 134 QIMESLNVLHSELKNKVE---TFSESRIFNELKTKMLNIKEYKEKLLSTLGEF---LEDH 187
+ L + K K+E E + + +K + IK+ + KL + + +F LED
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDA 1664
Query: 188 FPLPDR---SVKKKKKNIQESSVNLITLHEML 216
D + K+ +K + +L+ L E L
Sbjct: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Score = 28.1 bits (61), Expect = 8.4
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 19/150 (12%)
Query: 34 DMEECQNKL--SLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLIT 91
+ EE +L SL G L D +L I Q L EL + Q +
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQ---LEEELEEEQGNMEAMSDR-----VR 1760
Query: 92 LGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVE 151
++ ++L +L ST + KNE ++ LER+ + L + ME + S+ K+ +
Sbjct: 1761 KATQQAEQLSNELATERSTAQ-KNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIA 1817
Query: 152 TFS------ESRIFNELKTKMLNIKEYKEK 175
E ++ E + K K K+K
Sbjct: 1818 ALEAKIAQLEEQVEQEAREKQAATKSLKQK 1847
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 17/145 (11%)
Query: 73 QWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQ 132
QW + + PL + +T +EE Q +L+ TKE + + E E EQ+
Sbjct: 840 QWWRLFTKVKPLLQ---VTRQEEEMQAKEDELQ---KTKERQQKAENELKELEQK----H 889
Query: 133 QQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPD 192
Q+ E N+L +L+ + E ++E+ E++ ++ K+ E++L + LE+
Sbjct: 890 SQLTEEKNLLQEQLQAETELYAEA---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 946
Query: 193 RSVKKKKKNIQESSVNLITLHEMLE 217
+ ++KK Q+ ++ L E LE
Sbjct: 947 QLQAERKKMAQQ----MLDLEEQLE 967
Score = 33.5 bits (75), Expect = 0.20
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 33 KDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITL 92
+ +EE +N L + L + L + L +LS +KK + E +
Sbjct: 1346 RQLEEERNSLQ----DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE--ALEE 1399
Query: 93 GKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVET 152
GK+ FQK ++L K + +KL++ R Q+ LD+ +++ L S L+ K
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1459
Query: 153 FSE 155
F +
Sbjct: 1460 FDQ 1462
Score = 32.3 bits (72), Expect = 0.44
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 16/150 (10%)
Query: 19 NTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVK-------CLTAEL 71
+ ++L R+ +E+ + E + + T+ A+++ L QV+ T L
Sbjct: 1792 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1851
Query: 72 SQWQKKTPETIPLTEDV--LITLGKEEFQKLR---QDLEMVLSTKESKNEKLKEDLEREQ 126
Q KK E + ED + KE+ +K + L+ L E +++++ + + Q
Sbjct: 1852 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1911
Query: 127 RWLDEQQQIMESL----NVLHSELKNKVET 152
R LDE + E++ N L S+L+ ET
Sbjct: 1912 RELDEATESNEAMGREVNALKSKLRRGNET 1941
Score = 32.0 bits (71), Expect = 0.58
Identities = 46/212 (21%), Positives = 89/212 (41%), Gaps = 20/212 (9%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTET--LTDSNAQLSLLIMQVKCLTAELSQ 73
+ +EEL R + + +ME+ + +G L S L + ++K EL
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE- 1559
Query: 74 WQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQ 133
+ + TED + L + Q L+ E L ++ +NE+ + L+R+ + +
Sbjct: 1560 ------DELQATEDAKLRL-EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612
Query: 134 QIMESLNVLHSELKNKVE---TFSESRIFNELKTKMLNIKEYKEKLLSTLGEF---LEDH 187
+ L + K K+E E + + +K + IK+ + KL + + +F LED
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDA 1671
Query: 188 FPLPDR---SVKKKKKNIQESSVNLITLHEML 216
D + K+ +K + +L+ L E L
Sbjct: 1672 RASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Score = 28.1 bits (61), Expect = 8.4
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 19/150 (12%)
Query: 34 DMEECQNKL--SLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLIT 91
+ EE +L SL G L D +L I Q L EL + Q +
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQ---LEEELEEEQGNMEAMSDR-----VR 1767
Query: 92 LGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVE 151
++ ++L +L ST + KNE ++ LER+ + L + ME + S+ K+ +
Sbjct: 1768 KATQQAEQLSNELATERSTAQ-KNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIA 1824
Query: 152 TFS------ESRIFNELKTKMLNIKEYKEK 175
E ++ E + K K K+K
Sbjct: 1825 ALEAKIAQLEEQVEQEAREKQAATKSLKQK 1854
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 17/145 (11%)
Query: 73 QWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQ 132
QW + + PL + +T +EE Q +L+ TKE + + E E EQ+
Sbjct: 840 QWWRLFTKVKPLLQ---VTRQEEEMQAKEDELQ---KTKERQQKAENELKELEQK----H 889
Query: 133 QQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPD 192
Q+ E N+L +L+ + E ++E+ E++ ++ K+ E++L + LE+
Sbjct: 890 SQLTEEKNLLQEQLQAETELYAEA---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 946
Query: 193 RSVKKKKKNIQESSVNLITLHEMLE 217
+ ++KK Q+ ++ L E LE
Sbjct: 947 QLQAERKKMAQQ----MLDLEEQLE 967
Score = 33.5 bits (75), Expect = 0.20
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 33 KDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITL 92
+ +EE +N L + L + L + L +LS +KK + E +
Sbjct: 1346 RQLEEERNSLQ----DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE--ALEE 1399
Query: 93 GKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVET 152
GK+ FQK ++L K + +KL++ R Q+ LD+ +++ L S L+ K
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1459
Query: 153 FSE 155
F +
Sbjct: 1460 FDQ 1462
Score = 32.0 bits (71), Expect = 0.58
Identities = 46/212 (21%), Positives = 89/212 (41%), Gaps = 20/212 (9%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTET--LTDSNAQLSLLIMQVKCLTAELSQ 73
+ +EEL R + + +ME+ + +G L S L + ++K EL
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE- 1559
Query: 74 WQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQ 133
+ + TED + L + Q L+ E L ++ +NE+ + L+R+ + +
Sbjct: 1560 ------DELQATEDAKLRL-EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612
Query: 134 QIMESLNVLHSELKNKVE---TFSESRIFNELKTKMLNIKEYKEKLLSTLGEF---LEDH 187
+ L + K K+E E + + +K + IK+ + KL + + +F LED
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDA 1671
Query: 188 FPLPDR---SVKKKKKNIQESSVNLITLHEML 216
D + K+ +K + +L+ L E L
Sbjct: 1672 RASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Score = 31.2 bits (69), Expect = 0.99
Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 12/144 (8%)
Query: 19 NTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVK-------CLTAEL 71
+ ++L R+ +E+ + E + + T+ A+++ L QV+ T L
Sbjct: 1792 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1851
Query: 72 SQWQKKTPETIPLTEDV--LITLGKEEFQKLR---QDLEMVLSTKESKNEKLKEDLEREQ 126
Q KK E + ED + KE+ +K + L+ L E +++++ + + Q
Sbjct: 1852 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1911
Query: 127 RWLDEQQQIMESLNVLHSELKNKV 150
R LDE + E++ + LK+K+
Sbjct: 1912 RELDEATESNEAMGREVNALKSKL 1935
Score = 28.1 bits (61), Expect = 8.4
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 19/150 (12%)
Query: 34 DMEECQNKL--SLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLIT 91
+ EE +L SL G L D +L I Q L EL + Q +
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQ---LEEELEEEQGNMEAMSDR-----VR 1767
Query: 92 LGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVE 151
++ ++L +L ST + KNE ++ LER+ + L + ME + S+ K+ +
Sbjct: 1768 KATQQAEQLSNELATERSTAQ-KNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIA 1824
Query: 152 TFS------ESRIFNELKTKMLNIKEYKEK 175
E ++ E + K K K+K
Sbjct: 1825 ALEAKIAQLEEQVEQEAREKQAATKSLKQK 1854
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 17/145 (11%)
Query: 73 QWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQ 132
QW + + PL + +T +EE Q +L+ TKE + + E E EQ+
Sbjct: 833 QWWRLFTKVKPLLQ---VTRQEEEMQAKEDELQ---KTKERQQKAENELKELEQK----H 882
Query: 133 QQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPD 192
Q+ E N+L +L+ + E ++E+ E++ ++ K+ E++L + LE+
Sbjct: 883 SQLTEEKNLLQEQLQAETELYAEA---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 939
Query: 193 RSVKKKKKNIQESSVNLITLHEMLE 217
+ ++KK Q+ ++ L E LE
Sbjct: 940 QLQAERKKMAQQ----MLDLEEQLE 960
Score = 33.5 bits (75), Expect = 0.20
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 33 KDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITL 92
+ +EE +N L + L + L + L +LS +KK + E +
Sbjct: 1339 RQLEEERNSLQ----DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE--ALEE 1392
Query: 93 GKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVET 152
GK+ FQK ++L K + +KL++ R Q+ LD+ +++ L S L+ K
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1452
Query: 153 FSE 155
F +
Sbjct: 1453 FDQ 1455
Score = 32.0 bits (71), Expect = 0.58
Identities = 46/212 (21%), Positives = 89/212 (41%), Gaps = 20/212 (9%)
Query: 16 DVTNTEEELIRECEEMWKDMEECQNKLSLIGTET--LTDSNAQLSLLIMQVKCLTAELSQ 73
+ +EEL R + + +ME+ + +G L S L + ++K EL
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE- 1552
Query: 74 WQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQ 133
+ + TED + L + Q L+ E L ++ +NE+ + L+R+ + +
Sbjct: 1553 ------DELQATEDAKLRL-EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Query: 134 QIMESLNVLHSELKNKVE---TFSESRIFNELKTKMLNIKEYKEKLLSTLGEF---LEDH 187
+ L + K K+E E + + +K + IK+ + KL + + +F LED
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDA 1664
Query: 188 FPLPDR---SVKKKKKNIQESSVNLITLHEML 216
D + K+ +K + +L+ L E L
Sbjct: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Score = 31.2 bits (69), Expect = 0.99
Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 12/144 (8%)
Query: 19 NTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVK-------CLTAEL 71
+ ++L R+ +E+ + E + + T+ A+++ L QV+ T L
Sbjct: 1785 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1844
Query: 72 SQWQKKTPETIPLTEDV--LITLGKEEFQKLR---QDLEMVLSTKESKNEKLKEDLEREQ 126
Q KK E + ED + KE+ +K + L+ L E +++++ + + Q
Sbjct: 1845 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1904
Query: 127 RWLDEQQQIMESLNVLHSELKNKV 150
R LDE + E++ + LK+K+
Sbjct: 1905 RELDEATESNEAMGREVNALKSKL 1928
Score = 28.1 bits (61), Expect = 8.4
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 19/150 (12%)
Query: 34 DMEECQNKL--SLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLIT 91
+ EE +L SL G L D +L I Q L EL + Q +
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQ---LEEELEEEQGNMEAMSDR-----VR 1760
Query: 92 LGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVE 151
++ ++L +L ST + KNE ++ LER+ + L + ME + S+ K+ +
Sbjct: 1761 KATQQAEQLSNELATERSTAQ-KNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIA 1817
Query: 152 TFS------ESRIFNELKTKMLNIKEYKEK 175
E ++ E + K K K+K
Sbjct: 1818 ALEAKIAQLEEQVEQEAREKQAATKSLKQK 1847
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/186 (19%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Query: 46 GTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLE 105
G+ + D ++QL Q++ L A LS + ++ + E + I L K + +R+ E
Sbjct: 49 GSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQE 108
Query: 106 MVLSTKESKNEKLKEDL-----EREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFN 160
T ++ K+ E L ++Q W ++ Q+ + N+L ++L+ E ++S
Sbjct: 109 QN-ETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNILTAQLQ---EMKNQSMNLF 164
Query: 161 ELKTKMLNIKEYKEKLLSTLGEFL---EDHFPLPDRSVKKKKKNIQESSVNLITLHEMLE 217
+ + +M ++ ++++ LS + L E+ ++ ++ + + + + L+ ++M
Sbjct: 165 QRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSS 224
Query: 218 ILINRL 223
L +L
Sbjct: 225 DLSQKL 230
Score = 38.5 bits (88), Expect = 0.006
Identities = 42/161 (26%), Positives = 78/161 (48%), Gaps = 22/161 (13%)
Query: 16 DVTNTEEELIRECE---EMWKDMEECQNKLSLIGTE------TLTDSNAQLSLLIMQVKC 66
+++ T+EEL+ + ++ + +EE Q S + + + T + ++++ L + +
Sbjct: 208 ELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQE 267
Query: 67 LTAELSQW----QKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDL 122
L A + Q QK T ET EDV+ L +E+ L + LE LS +E E LKE
Sbjct: 268 LQALIQQLSIDLQKVTAETQE-KEDVITHL-QEKVASLEKRLEQNLSGEEHVQELLKEKT 325
Query: 123 EREQRWLDEQQQIM-------ESLNVLHSELKNKVETFSES 156
EQ D +QQ++ +++N L + ++ +T S
Sbjct: 326 LAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQAS 366
Score = 30.8 bits (68), Expect = 1.3
Identities = 22/85 (25%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Query: 67 LTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126
LTA+L + + ++ +++ G ++ Q+L + M+L +ES K++++LE
Sbjct: 149 LTAQLQEMKNQSMNLFQRRDEMDELEGFQQ-QELSKIKHMLLKKEESLG-KMEQELEART 206
Query: 127 RWLDEQQQIMESLNVLHSELKNKVE 151
R L Q+ + + N + S+L K+E
Sbjct: 207 RELSRTQEELMNSNQMSSDLSQKLE 231
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 40.0 bits (92), Expect = 0.002
Identities = 56/237 (23%), Positives = 103/237 (43%), Gaps = 53/237 (22%)
Query: 20 TEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTP 79
TE+EL + E + ++ Q KL L + TD+ A ++ L +++ + EL + Q++
Sbjct: 53 TEDELDKYSEAL----KDAQEKLEL-AEKKATDAEADVASLNRRIQLVEEELDRAQERLA 107
Query: 80 ETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMES- 138
+ E E +K + E + ES+ +K +E +E ++ L E + I E
Sbjct: 108 TALQKLE---------EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
Query: 139 ----------LNVLHSELKNKVET--FSESR---IFNELKTKMLNIKE------------ 171
L ++ S+L+ E SE + + ELKT N+K
Sbjct: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 218
Query: 172 --YKE--KLLSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNL-------ITLHEMLE 217
Y+E K+LS + E +RSV K +K+I + + +++H+ML+
Sbjct: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLD 275
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 39.7 bits (91), Expect = 0.003
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 23/152 (15%)
Query: 48 ETLTDSN-----AQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDV-LITLGKEEFQKLR 101
ETL N A L+ QV L AEL + KK EDV ++ + +EFQ+
Sbjct: 305 ETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERV 364
Query: 102 QDLEMVLSTKESKNEKLKE------DLEREQRWLDE------QQQIMESLNVLHSELKNK 149
+DLE +KL E D + W +E QQQ+ + + L +EL++K
Sbjct: 365 EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDK 424
Query: 150 ----VETFSESRIFNELKTKMLNI-KEYKEKL 176
+E E +LK ++ NI +++K+++
Sbjct: 425 RKVLLELSREKAQNEDLKLEVTNILQKHKQEV 456
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/138 (27%), Positives = 72/138 (52%), Gaps = 14/138 (10%)
Query: 96 EFQKLRQD-LEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMES----LNVLHSELKNKV 150
E +K ++D L L +E+ N K ++D L+ Q Q+++S L HS+L+ +
Sbjct: 81 EHKKAKEDFLVYKLEAQETLN-KGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEH 139
Query: 151 ETFSE--SRIFNELKTKMLNIKEYKEKLLSTLGEFL----EDHFPL--PDRSVKKKKKNI 202
E SR FN+ K K L +++ KE+ LS L E + E++ L + + + +++
Sbjct: 140 RKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDV 199
Query: 203 QESSVNLITLHEMLEILI 220
++ NL++ HE L + +
Sbjct: 200 KQQHKNLLSEHEQLVVTL 217
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,965,217
Number of Sequences: 37866
Number of extensions: 420187
Number of successful extensions: 3330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 460
Number of HSP's that attempted gapping in prelim test: 2431
Number of HSP's gapped (non-prelim): 1225
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.