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Search of human proteins with 110618256
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110618256 trace amine associated receptor 9 [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 708 0.0
gi|28173558 trace amine associated receptor 6 [Homo sapiens] 510 e-145
gi|16751917 trace amine associated receptor 8 [Homo sapiens] 491 e-139
gi|223633986 trace amine associated receptor 5 [Homo sapiens] 316 2e-86
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 289 2e-78
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 264 1e-70
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 254 6e-68
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 177 2e-44
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 177 2e-44
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 177 2e-44
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 177 2e-44
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 177 2e-44
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 177 2e-44
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 174 1e-43
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 169 3e-42
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 153 2e-37
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 153 2e-37
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 153 2e-37
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 153 2e-37
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 153 2e-37
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 153 2e-37
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 146 2e-35
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 145 4e-35
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 145 7e-35
gi|4503383 dopamine receptor D1 [Homo sapiens] 140 2e-33
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 140 2e-33
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 140 2e-33
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 139 3e-33
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 139 3e-33
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 139 3e-33
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 708 bits (1827), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF 60
MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
Sbjct: 1 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF 60
Query: 61 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL 120
KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
Sbjct: 61 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL 120
Query: 121 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL 180
FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
Sbjct: 121 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL 180
Query: 181 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS 240
VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
Sbjct: 181 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS 240
Query: 241 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV 300
SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
Sbjct: 241 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV 300
Query: 301 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD 348
YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
Sbjct: 301 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD 348
>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
Length = 345
Score = 510 bits (1314), Expect = e-145
Identities = 238/345 (68%), Positives = 283/345 (82%)
Query: 1 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF 60
M +N S AV+LCY NVN SC+K P+SPG R ILY V GFGAVLA FGNLLVMI+ILHF
Sbjct: 1 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF 60
Query: 61 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL 120
KQLH+PTNFL+ASLACADFLVGVTVMPFS VR+VESCWYFG S+C FHTC D +FC++SL
Sbjct: 61 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL 120
Query: 121 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL 180
FHLC IS+DRYIAVTDPL YPTKFTVSVSGICI +SW + YS ++FYTG ++G+EEL
Sbjct: 121 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL 180
Query: 181 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS 240
AL C+GGCQ +NQNWVL FL FFIP M+ +Y IFLVA+ QA+KIE+T S+ +S
Sbjct: 181 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES 240
Query: 241 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV 300
SSESYK RVA+RERKAAKTLG+ + AF++SWLPY +D++IDA+M FITP +YEI WC
Sbjct: 241 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA 300
Query: 301 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEV 345
YYNSAMNPLIYA FY WF KAIK+IV+G+VL+ S+T NLFSE +
Sbjct: 301 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI 345
>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
Length = 342
Score = 491 bits (1265), Expect = e-139
Identities = 232/343 (67%), Positives = 279/343 (81%), Gaps = 1/343 (0%)
Query: 1 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF 60
M +NFSQ V+LCY++VN SCI+TPYSPG R ILY FG++LA FGNLLVM ++LHF
Sbjct: 1 MTSNFSQP-VVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF 59
Query: 61 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL 120
KQLH+PTNFLIASLACADFLVGVTVM FS VR+VESCWYFG +C H+C D +FC++S+
Sbjct: 60 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV 119
Query: 121 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL 180
HLC I +DRYI VTDPL Y TKFTVSVSGICI +SW +TYS ++FYTG N++G+EEL
Sbjct: 120 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL 179
Query: 181 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS 240
V AL CVGGCQ ++Q WVL+ FLLFFIP + M+ +YSKIFL+AK QA KIE+T+S+ +S
Sbjct: 180 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES 239
Query: 241 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV 300
SSESYK RVAKRERKAAKTLG+ + AF++SWLPY VD +IDA+M F+TP Y+YEI W
Sbjct: 240 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA 299
Query: 301 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSE 343
YYNSAMNPLIYA FY WF KAIKLI+SG VL+ SST +LF E
Sbjct: 300 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 342
>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
Length = 337
Score = 316 bits (809), Expect = 2e-86
Identities = 153/330 (46%), Positives = 217/330 (65%), Gaps = 9/330 (2%)
Query: 14 CYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIAS 73
CY+ VN SC +T ++ G + ++Y G ++ GN+ V A+ +FK LHTPTNFL+ S
Sbjct: 17 CYQ-VNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLS 75
Query: 74 LACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIA 133
LA AD +G+ V+P ST+RSVESCW+FGD C+ HT DT FC S+FHLC IS+DR+ A
Sbjct: 76 LALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCA 135
Query: 134 VTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAP 193
+ DPL YP+KFTV V+ I+ W Y+ YT E + + + + CVG CQ
Sbjct: 136 ICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLL 195
Query: 194 LNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRE 253
LN+ W L F LFF+P + M+ +Y KIF+VA QA++I +T S++ + + AK E
Sbjct: 196 LNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQI-TTLSKSLAGA-------AKHE 247
Query: 254 RKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAF 313
RKAAKTLGIA+ +L+ WLP+ +D ++D+ ++FITPP V++I +W Y+NSA NP+IY F
Sbjct: 248 RKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVF 307
Query: 314 FYQWFGKAIKLIVSGKVLRTDSSTTNLFSE 343
YQWF KA+KL +S KV + T +L+ E
Sbjct: 308 SYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 289 bits (740), Expect = 2e-78
Identities = 141/332 (42%), Positives = 204/332 (61%), Gaps = 2/332 (0%)
Query: 14 CYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIAS 73
C+ +N SC+K +S R+ LY+++ + GNL+V+++I HFKQLHTPTN+LI S
Sbjct: 5 CHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHS 64
Query: 74 LACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIA 133
+A DFL+G VMP+S VRS E CWYFG+ +CK HT D AS+FHL IS+DRY A
Sbjct: 65 MATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYA 124
Query: 134 VTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVA-LTCVGGCQA 192
V DPL Y K + V + I +SW ++F + + N +G EE+ + C GGC
Sbjct: 125 VCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSV 184
Query: 193 PLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAK 251
++ +L F+ F+IP M+ +Y +I+L+AK QAR I + Q E
Sbjct: 185 FFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQS 244
Query: 252 RERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIY 311
+ERKA KTLGI M FL+ W P+ + V+D ++++I PP + ++L+W Y NS NP++Y
Sbjct: 245 KERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVY 304
Query: 312 AFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSE 343
AFFY WF KA+K+++ GK+ + DSS LF E
Sbjct: 305 AFFYPWFRKALKMMLFGKIFQKDSSRCKLFLE 336
>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
sapiens]
Length = 351
Score = 264 bits (674), Expect = 1e-70
Identities = 127/318 (39%), Positives = 186/318 (58%), Gaps = 9/318 (2%)
Query: 14 CYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIAS 73
C + N SC + S G R +Y+ + + FGNL ++I+I +FKQLHTPTNFLI S
Sbjct: 25 CSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILS 84
Query: 74 LACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIA 133
+A DFL+G T+MP+S +RSVE+CWYFG ++CK + FD S+FHLC +++DR+ A
Sbjct: 85 MAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYA 144
Query: 134 VTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAP 193
+ PL Y TK T+ V ++L W ++F + ++ A +GIE + + C C
Sbjct: 145 ICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVM 204
Query: 194 LNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKR 252
N+ W F+ FF P MV IY KIF V++ A I + + K+
Sbjct: 205 FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKK 256
Query: 253 ERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYA 312
++KAAKTLGI + FL+ W P ++D ++NF TP +++ L W Y+NS NPLIY
Sbjct: 257 DKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYG 316
Query: 313 FFYQWFGKAIKLIVSGKV 330
FFY WF +A+K I+ GK+
Sbjct: 317 FFYPWFRRALKYILLGKI 334
>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
sapiens]
Length = 306
Score = 254 bits (650), Expect = 6e-68
Identities = 120/297 (40%), Positives = 177/297 (59%), Gaps = 9/297 (3%)
Query: 35 LYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSV 94
+Y+ + + FGNL ++I+I +FKQLHTPTNFLI S+A DFL+G T+MP+S +RSV
Sbjct: 1 MYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSV 60
Query: 95 ESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIV 154
E+CWYFG ++CK + FD S+FHLC +++DR+ A+ PL Y TK T+ V ++
Sbjct: 61 ENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLL 120
Query: 155 LSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAM 213
L W ++F + ++ A +GIE + + C C N+ W F+ FF P M
Sbjct: 121 LCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMM 180
Query: 214 VFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLP 273
V IY KIF V++ A I + + K+++KAAKTLGI + FL+ W P
Sbjct: 181 VGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKKDKKAAKTLGIVIGVFLLCWFP 232
Query: 274 YLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKV 330
++D ++NF TP +++ L W Y+NS NPLIY FFY WF +A+K I+ GK+
Sbjct: 233 CFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKI 289
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 177 bits (448), Expect = 2e-44
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205
+ W SF G N GI +L+ C +N+ + + C ++
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258
F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK
Sbjct: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
Query: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318
TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F
Sbjct: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
Query: 319 GKAIKLIV 326
+A +I+
Sbjct: 320 RRAFLIIL 327
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 177 bits (448), Expect = 2e-44
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205
+ W SF G N GI +L+ C +N+ + + C ++
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258
F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK
Sbjct: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
Query: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318
TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F
Sbjct: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
Query: 319 GKAIKLIV 326
+A +I+
Sbjct: 320 RRAFLIIL 327
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 177 bits (448), Expect = 2e-44
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205
+ W SF G N GI +L+ C +N+ + + C ++
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258
F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK
Sbjct: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
Query: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318
TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F
Sbjct: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
Query: 319 GKAIKLIV 326
+A +I+
Sbjct: 320 RRAFLIIL 327
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 177 bits (448), Expect = 2e-44
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205
+ W SF G N GI +L+ C +N+ + + C ++
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258
F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK
Sbjct: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
Query: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318
TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F
Sbjct: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
Query: 319 GKAIKLIV 326
+A +I+
Sbjct: 320 RRAFLIIL 327
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 177 bits (448), Expect = 2e-44
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205
+ W SF G N GI +L+ C +N+ + + C ++
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258
F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK
Sbjct: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
Query: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318
TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F
Sbjct: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
Query: 319 GKAIKLIV 326
+A +I+
Sbjct: 320 RRAFLIIL 327
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 177 bits (448), Expect = 2e-44
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205
+ W SF G N GI +L+ C +N+ + + C ++
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258
F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK
Sbjct: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
Query: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318
TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F
Sbjct: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
Query: 319 GKAIKLIV 326
+A +I+
Sbjct: 320 RRAFLIIL 327
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 174 bits (440), Expect = 1e-43
Identities = 108/322 (33%), Positives = 162/322 (50%), Gaps = 30/322 (9%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-------------------CQA 192
+ W SF G N GI +L +L G C
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVF 200
Query: 193 PLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSES 244
+N+ + + C ++ F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ +
Sbjct: 201 MVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQH 260
Query: 245 YKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNS 304
R+ + E KAAKTL I M F + W P+ V ++D ++++ P V+ +W Y NS
Sbjct: 261 STHRM-RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINS 319
Query: 305 AMNPLIYAFFYQWFGKAIKLIV 326
+NP +YAF + F +A +I+
Sbjct: 320 GLNPFLYAFLNKSFRRAFLIIL 341
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 169 bits (429), Expect = 3e-42
Identities = 102/298 (34%), Positives = 155/298 (52%), Gaps = 28/298 (9%)
Query: 38 VLGFGAVLA------AFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTV 91
V+G G V++ FGN+LV+ AI F++L T TN+ I SLACAD ++G+ V+PF
Sbjct: 33 VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAA 92
Query: 92 RSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGI 151
+ W FG+ +C+F T D AS+ LC I+VDRY A+T P Y + T + + +
Sbjct: 93 HILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARV 152
Query: 152 CIVLSWFFSVTYSF----SIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-F 206
I++ W S SF +Y ++E I TC C NQ + + ++ F
Sbjct: 153 IILMVWIVSGLTSFLPIQMHWYRATHQEAI-NCYANETC---CDFFTNQAYAIASSIVSF 208
Query: 207 FIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAK-------------RE 253
++P V MVF+YS++F AK Q +KI+ + + + S E+ + +E
Sbjct: 209 YVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKE 268
Query: 254 RKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIY 311
KA KTLGI M F + WLP+ + ++ + + VY +L W Y NS NPLIY
Sbjct: 269 HKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIY 326
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 153 bits (387), Expect = 2e-37
Identities = 97/322 (30%), Positives = 157/322 (48%), Gaps = 37/322 (11%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRS 93
+L +LG + GN+LV++++ + LH+ T++ I +LA AD L+ TV+PFS +
Sbjct: 28 LLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87
Query: 94 VESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICI 153
V W FG +C D C AS+ LC IS+DRYI V+ PL YPT T + +
Sbjct: 88 VLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMAL 147
Query: 154 VLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFL-LFFIPNVA 212
+ W S+ S + +E + CQ +VL L F++P
Sbjct: 148 LCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEPGYVLFSALGSFYLPLAI 199
Query: 213 MVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAK--------------------- 251
++ +Y ++++VAK ++R ++S +S SE R+ +
Sbjct: 200 ILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSV 259
Query: 252 ------RERKAAKTLGIAMAAFLVSWLP-YLVDAVIDAYMNFITPPYVYEILVWCVYYNS 304
RE+KAAKTLGI + F++ WLP +LV + + +F V++I+ W Y NS
Sbjct: 260 RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 305 AMNPLIYAFFYQWFGKAIKLIV 326
+NP+IY Q F KA + ++
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVL 341
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 153 bits (387), Expect = 2e-37
Identities = 97/322 (30%), Positives = 157/322 (48%), Gaps = 37/322 (11%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRS 93
+L +LG + GN+LV++++ + LH+ T++ I +LA AD L+ TV+PFS +
Sbjct: 28 LLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87
Query: 94 VESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICI 153
V W FG +C D C AS+ LC IS+DRYI V+ PL YPT T + +
Sbjct: 88 VLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMAL 147
Query: 154 VLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFL-LFFIPNVA 212
+ W S+ S + +E + CQ +VL L F++P
Sbjct: 148 LCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEPGYVLFSALGSFYLPLAI 199
Query: 213 MVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAK--------------------- 251
++ +Y ++++VAK ++R ++S +S SE R+ +
Sbjct: 200 ILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSV 259
Query: 252 ------RERKAAKTLGIAMAAFLVSWLP-YLVDAVIDAYMNFITPPYVYEILVWCVYYNS 304
RE+KAAKTLGI + F++ WLP +LV + + +F V++I+ W Y NS
Sbjct: 260 RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 305 AMNPLIYAFFYQWFGKAIKLIV 326
+NP+IY Q F KA + ++
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVL 341
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 153 bits (387), Expect = 2e-37
Identities = 97/322 (30%), Positives = 157/322 (48%), Gaps = 37/322 (11%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRS 93
+L +LG + GN+LV++++ + LH+ T++ I +LA AD L+ TV+PFS +
Sbjct: 28 LLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87
Query: 94 VESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICI 153
V W FG +C D C AS+ LC IS+DRYI V+ PL YPT T + +
Sbjct: 88 VLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMAL 147
Query: 154 VLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFL-LFFIPNVA 212
+ W S+ S + +E + CQ +VL L F++P
Sbjct: 148 LCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEPGYVLFSALGSFYLPLAI 199
Query: 213 MVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAK--------------------- 251
++ +Y ++++VAK ++R ++S +S SE R+ +
Sbjct: 200 ILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSV 259
Query: 252 ------RERKAAKTLGIAMAAFLVSWLP-YLVDAVIDAYMNFITPPYVYEILVWCVYYNS 304
RE+KAAKTLGI + F++ WLP +LV + + +F V++I+ W Y NS
Sbjct: 260 RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 305 AMNPLIYAFFYQWFGKAIKLIV 326
+NP+IY Q F KA + ++
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVL 341
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 153 bits (387), Expect = 2e-37
Identities = 97/322 (30%), Positives = 157/322 (48%), Gaps = 37/322 (11%)
Query: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRS 93
+L +LG + GN+LV++++ + LH+ T++ I +LA AD L+ TV+PFS +
Sbjct: 28 LLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87
Query: 94 VESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICI 153
V W FG +C D C AS+ LC IS+DRYI V+ PL YPT T + +
Sbjct: 88 VLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMAL 147
Query: 154 VLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFL-LFFIPNVA 212
+ W S+ S + +E + CQ +VL L F++P
Sbjct: 148 LCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEPGYVLFSALGSFYLPLAI 199
Query: 213 MVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAK--------------------- 251
++ +Y ++++VAK ++R ++S +S SE R+ +
Sbjct: 200 ILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSV 259
Query: 252 ------RERKAAKTLGIAMAAFLVSWLP-YLVDAVIDAYMNFITPPYVYEILVWCVYYNS 304
RE+KAAKTLGI + F++ WLP +LV + + +F V++I+ W Y NS
Sbjct: 260 RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 305 AMNPLIYAFFYQWFGKAIKLIV 326
+NP+IY Q F KA + ++
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVL 341
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 153 bits (387), Expect = 2e-37
Identities = 100/307 (32%), Positives = 151/307 (49%), Gaps = 13/307 (4%)
Query: 38 VLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESC 97
VL ++ GN++V +A+ ++L TN I SLA D L+G+ V+PFS + +
Sbjct: 24 VLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCK 83
Query: 98 WYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSW 157
W FG +C +T D C AS+ +L IS+DRY AV DPL YP T I +VL W
Sbjct: 84 WSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIW 143
Query: 158 FFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFI 216
S+T SF + G N E C+ +N+ + L+ L+ F++P + M
Sbjct: 144 VISITLSFLSIHLGWNSR--NETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCIT 201
Query: 217 YSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLV 276
Y +IF VA+ QA++I +S ++ RE KA TL M AF++ W PY
Sbjct: 202 YYRIFKVARDQAKRINHISSWKAATI---------REHKATVTLAAVMGAFIICWFPYFT 252
Query: 277 DAVIDAYMNFITPPYVYE-ILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDS 335
V V E I++W Y NSA+NP++YA + F + + ++ +S
Sbjct: 253 AFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNS 312
Query: 336 STTNLFS 342
T+L S
Sbjct: 313 HKTSLRS 319
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 153 bits (387), Expect = 2e-37
Identities = 100/307 (32%), Positives = 151/307 (49%), Gaps = 13/307 (4%)
Query: 38 VLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESC 97
VL ++ GN++V +A+ ++L TN I SLA D L+G+ V+PFS + +
Sbjct: 24 VLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCK 83
Query: 98 WYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSW 157
W FG +C +T D C AS+ +L IS+DRY AV DPL YP T I +VL W
Sbjct: 84 WSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIW 143
Query: 158 FFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFI 216
S+T SF + G N E C+ +N+ + L+ L+ F++P + M
Sbjct: 144 VISITLSFLSIHLGWNSR--NETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCIT 201
Query: 217 YSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLV 276
Y +IF VA+ QA++I +S ++ RE KA TL M AF++ W PY
Sbjct: 202 YYRIFKVARDQAKRINHISSWKAATI---------REHKATVTLAAVMGAFIICWFPYFT 252
Query: 277 DAVIDAYMNFITPPYVYE-ILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDS 335
V V E I++W Y NSA+NP++YA + F + + ++ +S
Sbjct: 253 AFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNS 312
Query: 336 STTNLFS 342
T+L S
Sbjct: 313 HKTSLRS 319
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 146 bits (369), Expect = 2e-35
Identities = 99/317 (31%), Positives = 153/317 (48%), Gaps = 25/317 (7%)
Query: 26 PYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTV 85
P +PG + A L L A N L++ I L +NF + SL +D +VG+ V
Sbjct: 20 PSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVV 79
Query: 86 MPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFT 145
MP + + ++ W C T FD C AS+ +LC IS+DRY+ + PL Y + T
Sbjct: 80 MPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMT 139
Query: 146 VSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCF-L 204
+ ++ +W + SF G +E G V G C+ + +VL+ L
Sbjct: 140 PLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVP----GQCRLLASLPFVLVASGL 195
Query: 205 LFFIPNVAMVFIYSKIFLVAKHQARKIES-TASQAQSSSESY---------------KER 248
FF+P+ A+ F Y +I L A+ QA ++ S T A +SE+ +
Sbjct: 196 TFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRL 255
Query: 249 VAKRERKAAK---TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSA 305
K RKA K TLGI + F V+WLP+ V ++ A + I+P ++++L W Y NS
Sbjct: 256 ATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG-LFDVLTWLGYCNST 314
Query: 306 MNPLIYAFFYQWFGKAI 322
MNP+IY F + F +A+
Sbjct: 315 MNPIIYPLFMRDFKRAL 331
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 145 bits (367), Expect = 4e-35
Identities = 107/383 (27%), Positives = 167/383 (43%), Gaps = 76/383 (19%)
Query: 4 NFSQAEAVELCYKN-VNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQ 62
N S A + K+ + + I P+ + +L +L + N V+ + ++
Sbjct: 24 NLSSAPSQNCSAKDYIYQDSISLPW----KVLLVMLLALITLATTLSNAFVIATVYRTRK 79
Query: 63 LHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFH 122
LHTP N+LIASLA D LV + VMP ST+ +V W G C F D + C AS+ H
Sbjct: 80 LHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILH 139
Query: 123 LCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFY--TGANEEGIEEL 180
LC I++DRY A+TD + Y K T + + I L W FS++ S F+ EE + E
Sbjct: 140 LCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSEC 199
Query: 181 VVALTCVGGCQAPLNQNWVLLCFL----LFFIPNVAMVFIYSKIFLVAKHQARK------ 230
VV N + +L F+ P + ++ +Y +I++ A+ + K
Sbjct: 200 VV------------NTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRT 247
Query: 231 ----------------------IESTASQAQSSSES-----------------YKERVAK 251
I S S S S K+ +A
Sbjct: 248 GKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAA 307
Query: 252 RERKAAKTLGIAMAAFLVSWLPYLVDAVI-----DAYMNFITPPYVYEILVWCVYYNSAM 306
RERKA KTLGI + AF+V WLP+ + +++ DA + +++ W Y NS +
Sbjct: 308 RERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLA---IFDFFTWLGYLNSLI 364
Query: 307 NPLIYAFFYQWFGKAIKLIVSGK 329
NP+IY + F +A ++ K
Sbjct: 365 NPIIYTMSNEDFKQAFHKLIRFK 387
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 145 bits (365), Expect = 7e-35
Identities = 92/321 (28%), Positives = 150/321 (46%), Gaps = 40/321 (12%)
Query: 38 VLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESC 97
VLG + A GN+LV++++ + L TPTN+ I +LA AD L+ TV+PFS V
Sbjct: 51 VLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGY 110
Query: 98 WYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSW 157
W G +C D C AS+ LC IS+DRYI V L YPT T + + ++ W
Sbjct: 111 WVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVW 170
Query: 158 FFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFL-LFFIPNVAMVFI 216
S S ++ +T + P + L L F+IP ++ +
Sbjct: 171 VLSTVISIGPLLGWKEPAPNDDKECGVT-----EEPF---YALFSSLGSFYIPLAVILVM 222
Query: 217 YSKIFLVAKHQARKIESTASQAQSSSESYKERV--------------------------- 249
Y ++++VAK + +E+ + S+S+ R+
Sbjct: 223 YCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVK 282
Query: 250 ---AKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPP-YVYEILVWCVYYNSA 305
RE+KAAKTLGI + F++ WLP+ + + + + + PP V++++ W Y+NS
Sbjct: 283 LFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSC 342
Query: 306 MNPLIYAFFYQWFGKAIKLIV 326
+NP+IY + F +A I+
Sbjct: 343 LNPIIYPCSSKEFKRAFVRIL 363
>gi|4503383 dopamine receptor D1 [Homo sapiens]
Length = 446
Score = 140 bits (353), Expect = 2e-33
Identities = 93/295 (31%), Positives = 144/295 (48%), Gaps = 31/295 (10%)
Query: 49 GNLLVMIAILHFKQLHTP-TNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKF 107
GN LV A++ F+ L + TNF + SLA +D LV V VMP+ V + W FG S+C
Sbjct: 40 GNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFG-SFCNI 98
Query: 108 HTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSF-- 165
FD AS+ +LC ISVDRY A++ P Y K T + I I ++W SV SF
Sbjct: 99 WVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIP 158
Query: 166 ---SIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIF 221
S + C + L++ + + ++ F+IP M+ Y++I+
Sbjct: 159 VQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIY 218
Query: 222 LVAKHQARKI---ESTASQAQ--------------SSSESYKERVAKRERKAAKTLGIAM 264
+A+ Q R+I E A A+ S ES + KRE K KTL + M
Sbjct: 219 RIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIM 278
Query: 265 AAFLVSWLP-YLVDAVIDAYMNFITPPY-----VYEILVWCVYYNSAMNPLIYAF 313
F+ WLP ++++ ++ + T P+ +++ VW + NS++NP+IYAF
Sbjct: 279 GVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAF 333
>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
sapiens]
Length = 366
Score = 140 bits (352), Expect = 2e-33
Identities = 107/350 (30%), Positives = 157/350 (44%), Gaps = 62/350 (17%)
Query: 31 PRSILYAVLGFG-AVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFS 89
P IL ++ G A++ N LV+ AI+ ++LH P N+LI SLA DFLV V VMPFS
Sbjct: 21 PSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFS 80
Query: 90 TVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVS 149
V V W G C D + C S+ HL I++DRY A+TD + Y K T +
Sbjct: 81 IVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHA 140
Query: 150 GICIVLSWFFSVTYSF-SIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFI 208
GI I + W SV S +F+ +E ++ + + + F F+I
Sbjct: 141 GIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHI--------VSTIYSTFGAFYI 192
Query: 209 PNVAMVFIYSKIFLVA-----KHQARKI-----------ESTASQAQSSSESY------- 245
P ++ +Y KI+ A K QA +I ES +S S SY
Sbjct: 193 PLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLS 252
Query: 246 ---------------------------KERVA-KRERKAAKTLGIAMAAFLVSWLPYLV- 276
+++++ RERKAA TLG+ + AF++ WLP+ V
Sbjct: 253 DPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVK 312
Query: 277 DAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIV 326
+ V++ + L W Y NS +NPLIY F + F KA + +V
Sbjct: 313 ELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLV 362
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 140 bits (352), Expect = 2e-33
Identities = 100/344 (29%), Positives = 149/344 (43%), Gaps = 65/344 (18%)
Query: 35 LYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSV 94
L VL + N V+ IL ++LHTP N+LI SLA D LV + VMP S ++
Sbjct: 41 LAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTI 100
Query: 95 ESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIV 154
W FG C D + C AS+ HLC I++DRY A+TD L Y + T + I
Sbjct: 101 THTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIA 160
Query: 155 LSWFFSVTYSFSIFY---TGANEEGIEELV----VALTCVGGCQAPLNQNWVLLCFLLFF 207
+ W S+ S + A EE + LV ++ T C A F+
Sbjct: 161 IVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGA-------------FY 207
Query: 208 IPNVAMVFIYSKIFLVAKHQ--------------ARKIESTASQAQSSSES--------- 244
IP+V ++ +Y +I+ A+++ A I +A + S S
Sbjct: 208 IPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHS 267
Query: 245 --------------------YKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYM 284
K A RERKA K LGI + AF++ WLP+ V +++
Sbjct: 268 AGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPIC 327
Query: 285 --NFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIV 326
+ P +++ W Y NS +NP+IY F + F +A + IV
Sbjct: 328 RDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIV 371
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 139 bits (351), Expect = 3e-33
Identities = 94/320 (29%), Positives = 146/320 (45%), Gaps = 40/320 (12%)
Query: 27 YSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVM 86
Y + ++ ++L +L GN LV+I++ K+L P+N+LI SLA AD V V VM
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVM 135
Query: 87 PFSTVRS-VESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFT 145
PF +V + W FG +C D C AS+ LC IS+DRY+ +T PLTYP +
Sbjct: 136 PFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN 195
Query: 146 VSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL 205
I+ W S + + + A +++ + G + +
Sbjct: 196 GKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFG--------YTIYSTAVA 247
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARK--------------------------IESTASQAQ 239
F+IP M+F+Y +I+ A+ A K +E A+ ++
Sbjct: 248 FYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSR 307
Query: 240 SSSESYKE-RVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFIT----PPYVYE 294
K + KRE+KAA TLGI + AF V WLP+ + + ++ + P +V
Sbjct: 308 LLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVER 367
Query: 295 ILVWCVYYNSAMNPLIYAFF 314
+W Y NS +NP IYAFF
Sbjct: 368 TFLWLGYANSLINPFIYAFF 387
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 139 bits (351), Expect = 3e-33
Identities = 94/320 (29%), Positives = 146/320 (45%), Gaps = 40/320 (12%)
Query: 27 YSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVM 86
Y + ++ ++L +L GN LV+I++ K+L P+N+LI SLA AD V V VM
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVM 135
Query: 87 PFSTVRS-VESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFT 145
PF +V + W FG +C D C AS+ LC IS+DRY+ +T PLTYP +
Sbjct: 136 PFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN 195
Query: 146 VSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL 205
I+ W S + + + A +++ + G + +
Sbjct: 196 GKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFG--------YTIYSTAVA 247
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARK--------------------------IESTASQAQ 239
F+IP M+F+Y +I+ A+ A K +E A+ ++
Sbjct: 248 FYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSR 307
Query: 240 SSSESYKE-RVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFIT----PPYVYE 294
K + KRE+KAA TLGI + AF V WLP+ + + ++ + P +V
Sbjct: 308 LLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVER 367
Query: 295 ILVWCVYYNSAMNPLIYAFF 314
+W Y NS +NP IYAFF
Sbjct: 368 TFLWLGYANSLINPFIYAFF 387
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 139 bits (351), Expect = 3e-33
Identities = 94/320 (29%), Positives = 146/320 (45%), Gaps = 40/320 (12%)
Query: 27 YSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVM 86
Y + ++ ++L +L GN LV+I++ K+L P+N+LI SLA AD V V VM
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVM 135
Query: 87 PFSTVRS-VESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFT 145
PF +V + W FG +C D C AS+ LC IS+DRY+ +T PLTYP +
Sbjct: 136 PFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN 195
Query: 146 VSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL 205
I+ W S + + + A +++ + G + +
Sbjct: 196 GKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFG--------YTIYSTAVA 247
Query: 206 FFIPNVAMVFIYSKIFLVAKHQARK--------------------------IESTASQAQ 239
F+IP M+F+Y +I+ A+ A K +E A+ ++
Sbjct: 248 FYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSR 307
Query: 240 SSSESYKE-RVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFIT----PPYVYE 294
K + KRE+KAA TLGI + AF V WLP+ + + ++ + P +V
Sbjct: 308 LLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVER 367
Query: 295 ILVWCVYYNSAMNPLIYAFF 314
+W Y NS +NP IYAFF
Sbjct: 368 TFLWLGYANSLINPFIYAFF 387
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.138 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,916,483
Number of Sequences: 37866
Number of extensions: 467165
Number of successful extensions: 3152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 522
Number of HSP's successfully gapped in prelim test: 224
Number of HSP's that attempted gapping in prelim test: 1723
Number of HSP's gapped (non-prelim): 955
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.