BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|16751917 trace amine associated receptor 8 [Homo sapiens] (342 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|16751917 trace amine associated receptor 8 [Homo sapiens] 687 0.0 gi|28173558 trace amine associated receptor 6 [Homo sapiens] 566 e-161 gi|110618256 trace amine associated receptor 9 [Homo sapiens] 491 e-139 gi|223633986 trace amine associated receptor 5 [Homo sapiens] 306 2e-83 gi|21264324 trace amine associated receptor 1 [Homo sapiens] 271 5e-73 gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 250 1e-66 gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 237 1e-62 gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 170 2e-42 gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 170 2e-42 gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 170 2e-42 gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 170 2e-42 gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 170 2e-42 gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 170 2e-42 gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 169 4e-42 gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 154 1e-37 gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 154 1e-37 gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 154 1e-37 gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 154 1e-37 gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 146 3e-35 gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 144 1e-34 gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 144 1e-34 gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 143 3e-34 gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 141 7e-34 gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 140 1e-33 gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 139 3e-33 gi|4503383 dopamine receptor D1 [Homo sapiens] 139 5e-33 gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 135 4e-32 gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 135 4e-32 gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 135 4e-32 gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 134 2e-31 >gi|16751917 trace amine associated receptor 8 [Homo sapiens] Length = 342 Score = 687 bits (1773), Expect = 0.0 Identities = 342/342 (100%), Positives = 342/342 (100%) Query: 1 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK 60 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK Sbjct: 1 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK 60 Query: 61 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL 120 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL Sbjct: 61 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL 120 Query: 121 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV 180 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV Sbjct: 121 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV 180 Query: 181 SALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS 240 SALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS Sbjct: 181 SALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS 240 Query: 241 SESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAY 300 SESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAY Sbjct: 241 SESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAY 300 Query: 301 YNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 342 YNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE Sbjct: 301 YNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 342 >gi|28173558 trace amine associated receptor 6 [Homo sapiens] Length = 345 Score = 566 bits (1458), Expect = e-161 Identities = 273/343 (79%), Positives = 303/343 (88%), Gaps = 1/343 (0%) Query: 1 MTSNFSQPV-VQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF 59 M+SN S V VQLCY +VNGSC++ P+SPGSRVILY F FG++LAVFGNLLVM S+LHF Sbjct: 1 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF 60 Query: 60 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV 119 KQLHSPTNFL+ASLACADFLVGVTVM FSMVRTVESCWYFG FCT H+CCDVAFCYSS+ Sbjct: 61 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL 120 Query: 120 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL 179 HLCFI IDRYI VTDPLVY TKFTVSVSGICISVSWILPL YSGAVFYTGV DDGLEEL Sbjct: 121 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL 180 Query: 180 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES 239 ALNC+GGCQ +V+Q WVL DFL FFIPT +MIILY IFL+A++QA KIE T SK ES Sbjct: 181 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES 240 Query: 240 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA 299 SSESYK RVA+RERKAAKTLGVTV+AF+ISWLPY++D LIDAFMGF+TPA IYEICCW A Sbjct: 241 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA 300 Query: 300 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 342 YYNSAMNPLIYALFYPWFRKAIK+I++G VLK SS+T++LF E Sbjct: 301 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSE 343 >gi|110618256 trace amine associated receptor 9 [Homo sapiens] Length = 348 Score = 491 bits (1265), Expect = e-139 Identities = 232/343 (67%), Positives = 279/343 (81%), Gaps = 1/343 (0%) Query: 1 MTSNFSQP-VVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF 59 M +NFSQ V+LCY++VN SCI+TPYSPG R ILY FG++LA FGNLLVM ++LHF Sbjct: 1 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF 60 Query: 60 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV 119 KQLH+PTNFLIASLACADFLVGVTVM FS VR+VESCWYFG +C H+C D +FC++S+ Sbjct: 61 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL 120 Query: 120 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL 179 HLC I +DRYI VTDPL Y TKFTVSVSGICI +SW +TYS ++FYTG N++G+EEL Sbjct: 121 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL 180 Query: 180 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES 239 V AL CVGGCQ ++Q WVL+ FLLFFIP + M+ +YSKIFL+AK QA KIE+T+S+ +S Sbjct: 181 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS 240 Query: 240 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA 299 SSESYK RVAKRERKAAKTLG+ + AF++SWLPY VD +IDA+M F+TP Y+YEI W Sbjct: 241 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV 300 Query: 300 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 342 YYNSAMNPLIYA FY WF KAIKLI+SG VL+ SST +LF E Sbjct: 301 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSE 343 >gi|223633986 trace amine associated receptor 5 [Homo sapiens] Length = 337 Score = 306 bits (783), Expect = 2e-83 Identities = 146/330 (44%), Positives = 215/330 (65%), Gaps = 9/330 (2%) Query: 13 CYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIAS 72 CY+ VNGSC T ++ G ++++Y A + G L+ V GN+ V +V +FK LH+PTNFL+ S Sbjct: 17 CYQ-VNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLS 75 Query: 73 LACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIV 132 LA AD +G+ V+ S +R+VESCW+FG C LH+ D FC +S+ HLCFI IDR+ Sbjct: 76 LALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCA 135 Query: 133 VTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQII 192 + DPL+Y +KFTV V+ I W +P Y+ YT V + L + + + CVG CQ++ Sbjct: 136 ICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLL 195 Query: 193 VSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRE 252 +++ W ++F LFF+P L+MI LY KIF++A +QA +I T S + + AK E Sbjct: 196 LNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------AKHE 247 Query: 253 RKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYAL 312 RKAAKTLG+ V +++ WLP+T+D ++D+ + F+TP +++I W AY+NSA NP+IY Sbjct: 248 RKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVF 307 Query: 313 FYPWFRKAIKLILSGDVLKASSSTISLFLE 342 Y WFRKA+KL LS V + T+ L+ E Sbjct: 308 SYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337 >gi|21264324 trace amine associated receptor 1 [Homo sapiens] Length = 339 Score = 271 bits (694), Expect = 5e-73 Identities = 133/336 (39%), Positives = 201/336 (59%), Gaps = 2/336 (0%) Query: 9 VVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNF 68 ++ C+ +N SC++ +S R LY+ L + GNL+V+ S+ HFKQLH+PTN+ Sbjct: 1 MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW 60 Query: 69 LIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICID 128 LI S+A DFL+G VM +SMVR+ E CWYFG FC +H+ D+ +S+ HL FI ID Sbjct: 61 LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID 120 Query: 129 RYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL-VSALNCVG 187 RY V DPL Y K + V + I +SW +P ++ + + +N G EE+ ++C G Sbjct: 121 RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRG 180 Query: 188 GCQIIVSQ-GWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKI 246 GC + S+ VL F+IP +M+ +Y +I+LIAK+QA I + K++ E Sbjct: 181 GCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNG 240 Query: 247 RVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMN 306 +ERKA KTLG+ + F+I W P+ + ++D F+ ++ P + ++ W Y NS N Sbjct: 241 ISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFN 300 Query: 307 PLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 342 P++YA FYPWFRKA+K++L G + + SS LFLE Sbjct: 301 PMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLE 336 >gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sapiens] Length = 351 Score = 250 bits (639), Expect = 1e-66 Identities = 120/321 (37%), Positives = 187/321 (58%), Gaps = 9/321 (2%) Query: 13 CYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIAS 72 C E N SC E S G RV +Y+ + + +FGNL ++ S+ +FKQLH+PTNFLI S Sbjct: 25 CSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILS 84 Query: 73 LACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIV 132 +A DFL+G T+M +SM+R+VE+CWYFG FC ++ D+ +S+ HLC + IDR+ Sbjct: 85 MAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYA 144 Query: 133 VTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQII 192 + PL+Y+TK T+ V + + W +P ++ V ++ DG+E + C C ++ Sbjct: 145 ICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVM 204 Query: 193 VSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKR 251 ++ W F+ FF P +M+ +Y KIF ++++ A I + K+ Sbjct: 205 FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKK 256 Query: 252 ERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYA 311 ++KAAKTLG+ + F++ W P IL+D F+ F TP +++ W Y+NS NPLIY Sbjct: 257 DKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYG 316 Query: 312 LFYPWFRKAIKLILSGDVLKA 332 FYPWFR+A+K IL G + + Sbjct: 317 FFYPWFRRALKYILLGKIFSS 337 >gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sapiens] Length = 306 Score = 237 bits (604), Expect = 1e-62 Identities = 112/298 (37%), Positives = 178/298 (59%), Gaps = 10/298 (3%) Query: 37 AFSFGSL-LAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVES 95 +F GS+ + +FGNL ++ S+ +FKQLH+PTNFLI S+A DFL+G T+M +SM+R+VE+ Sbjct: 3 SFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVEN 62 Query: 96 CWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVS 155 CWYFG FC ++ D+ +S+ HLC + IDR+ + PL+Y+TK T+ V + + Sbjct: 63 CWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLC 122 Query: 156 WILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMII 214 W +P ++ V ++ DG+E + C C ++ ++ W F+ FF P +M+ Sbjct: 123 WSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVG 182 Query: 215 LYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYT 274 +Y KIF ++++ A I + K+++KAAKTLG+ + F++ W P Sbjct: 183 IYGKIFAVSRKHAHAINNLRENQNNQ--------VKKDKKAAKTLGIVIGVFLLCWFPCF 234 Query: 275 VDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKA 332 IL+D F+ F TP +++ W Y+NS NPLIY FYPWFR+A+K IL G + + Sbjct: 235 FTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSS 292 >gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] Length = 359 Score = 170 bits (430), Expect = 2e-42 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%) Query: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 Query: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 Query: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195 K T + + W++P S G N+ G+ +L+ C +V++ Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190 Query: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248 + + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ + Sbjct: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250 Query: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308 + E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP Sbjct: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310 Query: 309 IYALFYPWFRKAIKLILSGD 328 +YA FR+A +IL D Sbjct: 311 LYAFLNKSFRRAFLIILCCD 330 >gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] Length = 428 Score = 170 bits (430), Expect = 2e-42 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%) Query: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 Query: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 Query: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195 K T + + W++P S G N+ G+ +L+ C +V++ Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190 Query: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248 + + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ + Sbjct: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250 Query: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308 + E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP Sbjct: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310 Query: 309 IYALFYPWFRKAIKLILSGD 328 +YA FR+A +IL D Sbjct: 311 LYAFLNKSFRRAFLIILCCD 330 >gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] Length = 360 Score = 170 bits (430), Expect = 2e-42 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%) Query: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 Query: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 Query: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195 K T + + W++P S G N+ G+ +L+ C +V++ Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190 Query: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248 + + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ + Sbjct: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250 Query: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308 + E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP Sbjct: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310 Query: 309 IYALFYPWFRKAIKLILSGD 328 +YA FR+A +IL D Sbjct: 311 LYAFLNKSFRRAFLIILCCD 330 >gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] Length = 387 Score = 170 bits (430), Expect = 2e-42 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%) Query: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 Query: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 Query: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195 K T + + W++P S G N+ G+ +L+ C +V++ Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190 Query: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248 + + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ + Sbjct: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250 Query: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308 + E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP Sbjct: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310 Query: 309 IYALFYPWFRKAIKLILSGD 328 +YA FR+A +IL D Sbjct: 311 LYAFLNKSFRRAFLIILCCD 330 >gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] Length = 378 Score = 170 bits (430), Expect = 2e-42 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%) Query: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 Query: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 Query: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195 K T + + W++P S G N+ G+ +L+ C +V++ Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190 Query: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248 + + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ + Sbjct: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250 Query: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308 + E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP Sbjct: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310 Query: 309 IYALFYPWFRKAIKLILSGD 328 +YA FR+A +IL D Sbjct: 311 LYAFLNKSFRRAFLIILCCD 330 >gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] Length = 388 Score = 170 bits (430), Expect = 2e-42 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%) Query: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 Query: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 Query: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195 K T + + W++P S G N+ G+ +L+ C +V++ Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190 Query: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248 + + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ + Sbjct: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250 Query: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308 + E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP Sbjct: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310 Query: 309 IYALFYPWFRKAIKLILSGD 328 +YA FR+A +IL D Sbjct: 311 LYAFLNKSFRRAFLIILCCD 330 >gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] Length = 402 Score = 169 bits (427), Expect = 4e-42 Identities = 104/334 (31%), Positives = 164/334 (49%), Gaps = 28/334 (8%) Query: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 Query: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 Query: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG------------ 188 K T + + W++P S G N+ G+ +L +LN G Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFN 190 Query: 189 -------CQIIVSQGW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTS 234 C +V++ + + + F+IP L+M++ Y +I++ AK+ A +I+ +S Sbjct: 191 QNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASS 250 Query: 235 SKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEI 294 S++ + + E KAAKTL + + F + W P+ V ++D F+ + P ++ Sbjct: 251 ESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA 310 Query: 295 CCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGD 328 W Y NS +NP +YA FR+A +IL D Sbjct: 311 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCD 344 >gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] Length = 455 Score = 154 bits (389), Expect = 1e-37 Identities = 104/339 (30%), Positives = 168/339 (49%), Gaps = 39/339 (11%) Query: 18 NGSCIETPYSPG-SRVILYTAFSFGSLL-AVFGNLLVMTSVLHFKQLHSPTNFLIASLAC 75 + +C + P S+ IL G +L V GN+LV+ SV + LHS T++ I +LA Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70 Query: 76 ADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTD 135 AD L+ TV+ FS + V W FG FC + + DV C +S++ LC I IDRYI V+ Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130 Query: 136 PLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQ 195 PL Y T T + + W L L S + +E + CQI Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEP 182 Query: 196 GWVLIDFL-LFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAK---- 250 G+VL L F++P +++++Y +++++AK+++ +++ +S SE +R+ + Sbjct: 183 GYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242 Query: 251 -----------------------RERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLT 287 RE+KAAKTLG+ V FV+ WLP+ + + I +F Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302 Query: 288 PA-YIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 P+ +++I W Y NS +NP+IY F+KA + +L Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] Length = 466 Score = 154 bits (389), Expect = 1e-37 Identities = 104/339 (30%), Positives = 168/339 (49%), Gaps = 39/339 (11%) Query: 18 NGSCIETPYSPG-SRVILYTAFSFGSLL-AVFGNLLVMTSVLHFKQLHSPTNFLIASLAC 75 + +C + P S+ IL G +L V GN+LV+ SV + LHS T++ I +LA Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70 Query: 76 ADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTD 135 AD L+ TV+ FS + V W FG FC + + DV C +S++ LC I IDRYI V+ Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130 Query: 136 PLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQ 195 PL Y T T + + W L L S + +E + CQI Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEP 182 Query: 196 GWVLIDFL-LFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAK---- 250 G+VL L F++P +++++Y +++++AK+++ +++ +S SE +R+ + Sbjct: 183 GYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242 Query: 251 -----------------------RERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLT 287 RE+KAAKTLG+ V FV+ WLP+ + + I +F Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302 Query: 288 PA-YIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 P+ +++I W Y NS +NP+IY F+KA + +L Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] Length = 475 Score = 154 bits (389), Expect = 1e-37 Identities = 104/339 (30%), Positives = 168/339 (49%), Gaps = 39/339 (11%) Query: 18 NGSCIETPYSPG-SRVILYTAFSFGSLL-AVFGNLLVMTSVLHFKQLHSPTNFLIASLAC 75 + +C + P S+ IL G +L V GN+LV+ SV + LHS T++ I +LA Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70 Query: 76 ADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTD 135 AD L+ TV+ FS + V W FG FC + + DV C +S++ LC I IDRYI V+ Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130 Query: 136 PLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQ 195 PL Y T T + + W L L S + +E + CQI Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEP 182 Query: 196 GWVLIDFL-LFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAK---- 250 G+VL L F++P +++++Y +++++AK+++ +++ +S SE +R+ + Sbjct: 183 GYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242 Query: 251 -----------------------RERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLT 287 RE+KAAKTLG+ V FV+ WLP+ + + I +F Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302 Query: 288 PA-YIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 P+ +++I W Y NS +NP+IY F+KA + +L Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] Length = 429 Score = 154 bits (389), Expect = 1e-37 Identities = 104/339 (30%), Positives = 168/339 (49%), Gaps = 39/339 (11%) Query: 18 NGSCIETPYSPG-SRVILYTAFSFGSLL-AVFGNLLVMTSVLHFKQLHSPTNFLIASLAC 75 + +C + P S+ IL G +L V GN+LV+ SV + LHS T++ I +LA Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70 Query: 76 ADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTD 135 AD L+ TV+ FS + V W FG FC + + DV C +S++ LC I IDRYI V+ Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130 Query: 136 PLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQ 195 PL Y T T + + W L L S + +E + CQI Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETI--------CQINEEP 182 Query: 196 GWVLIDFL-LFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAK---- 250 G+VL L F++P +++++Y +++++AK+++ +++ +S SE +R+ + Sbjct: 183 GYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242 Query: 251 -----------------------RERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLT 287 RE+KAAKTLG+ V FV+ WLP+ + + I +F Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302 Query: 288 PA-YIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 P+ +++I W Y NS +NP+IY F+KA + +L Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] Length = 413 Score = 146 bits (368), Expect = 3e-35 Identities = 90/301 (29%), Positives = 149/301 (49%), Gaps = 23/301 (7%) Query: 43 LLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAK 102 L VFGN+LV+T++ F++L + TN+ I SLACAD ++G+ V+ F + W FG Sbjct: 45 LAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNF 104 Query: 103 FCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTY 162 +C + DV +S+ LC I +DRY +T P Y + T + + + I + WI+ Sbjct: 105 WCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIV---- 160 Query: 163 SGAVFYTGVNDDGLEEL-VSALNCVGG---CQIIVSQGWVLIDFLL-FFIPTLVMIILYS 217 SG + + A+NC C +Q + + ++ F++P ++M+ +YS Sbjct: 161 SGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYS 220 Query: 218 KIFLIAKQQAIKIETTS--------SKVESSSES-----YKIRVAKRERKAAKTLGVTVL 264 ++F AK+Q KI+ + S+VE + + +E KA KTLG+ + Sbjct: 221 RVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMG 280 Query: 265 AFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLI 324 F + WLP+ + ++ L +Y + W Y NS NPLIY P FR A + + Sbjct: 281 TFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQEL 339 Query: 325 L 325 L Sbjct: 340 L 340 >gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] Length = 397 Score = 144 bits (362), Expect = 1e-34 Identities = 95/299 (31%), Positives = 148/299 (49%), Gaps = 13/299 (4%) Query: 43 LLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAK 102 L+ V GN++V +V ++L + TN I SLA D L+G+ V+ FS + + W FG Sbjct: 30 LITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKV 89 Query: 103 FCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTY 162 FC +++ DV C +S+L+L I +DRY V DPL Y T I + + W++ +T Sbjct: 90 FCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITL 149 Query: 163 SGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFL 221 S + G N E + C++ V++ + L+D L+ F++P L+M I Y +IF Sbjct: 150 SFLSIHLGWN--SRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFK 207 Query: 222 IAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDA 281 +A+ QA +I SS ++ RE KA TL + AF+I W PY + Sbjct: 208 VARDQAKRINHISSWKAATI---------REHKATVTLAAVMGAFIICWFPYFTAFVYRG 258 Query: 282 FMGFLTPAYIYE-ICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISL 339 G + E I W Y NSA+NP++YA FR + + + +S SL Sbjct: 259 LRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSL 317 >gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] Length = 359 Score = 144 bits (362), Expect = 1e-34 Identities = 95/299 (31%), Positives = 148/299 (49%), Gaps = 13/299 (4%) Query: 43 LLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAK 102 L+ V GN++V +V ++L + TN I SLA D L+G+ V+ FS + + W FG Sbjct: 30 LITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKV 89 Query: 103 FCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTY 162 FC +++ DV C +S+L+L I +DRY V DPL Y T I + + W++ +T Sbjct: 90 FCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITL 149 Query: 163 SGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFL 221 S + G N E + C++ V++ + L+D L+ F++P L+M I Y +IF Sbjct: 150 SFLSIHLGWN--SRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFK 207 Query: 222 IAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDA 281 +A+ QA +I SS ++ RE KA TL + AF+I W PY + Sbjct: 208 VARDQAKRINHISSWKAATI---------REHKATVTLAAVMGAFIICWFPYFTAFVYRG 258 Query: 282 FMGFLTPAYIYE-ICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISL 339 G + E I W Y NSA+NP++YA FR + + + +S SL Sbjct: 259 LRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSL 317 >gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sapiens] Length = 390 Score = 143 bits (360), Expect = 3e-34 Identities = 106/345 (30%), Positives = 164/345 (47%), Gaps = 60/345 (17%) Query: 31 RVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMV 90 +V+L + +L N V+ +V ++LH+P N+LIASLA D LV + VM S + Sbjct: 49 KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTM 108 Query: 91 RTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGI 150 TV W G C D+ C +S+LHLC I +DRY +TD + Y+ K T + + Sbjct: 109 YTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAV 168 Query: 151 CISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTL 210 I++ W+ ++ S F+ EE VS CV I+ + + F+ PTL Sbjct: 169 MIALVWVFSISISLPPFFW--RQAKAEEEVS--ECVVNTDHILYTVYSTVG--AFYFPTL 222 Query: 211 VMIILYSKIFLIAKQQAIK-------------------------IETTSSKV-----ESS 240 ++I LY +I++ A+ + +K + + +S+V ES Sbjct: 223 LLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESG 282 Query: 241 SESY----KIRV-----------AKRERKAAKTLGVTVLAFVISWLPYTVDILI-----D 280 S Y K+RV A RERKA KTLG+ + AF++ WLP+ + L+ D Sbjct: 283 SPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKD 342 Query: 281 AFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAI-KLI 324 A L I++ W Y NS +NP+IY + F++A KLI Sbjct: 343 ACWFHLA---IFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLI 384 >gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] Length = 520 Score = 141 bits (356), Expect = 7e-34 Identities = 95/315 (30%), Positives = 149/315 (47%), Gaps = 40/315 (12%) Query: 43 LLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAK 102 L A+ GN+LV+ SV + L +PTN+ I +LA AD L+ TV+ FS V W G Sbjct: 57 LFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRI 116 Query: 103 FCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTY 162 FC + + DV C +S+L LC I IDRYI V L Y T T + + + W+L Sbjct: 117 FCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVI 176 Query: 163 SGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFL-LFFIPTLVMIILYSKIFL 221 S G +E A N C + + L L F+IP V++++Y ++++ Sbjct: 177 SIGPLL------GWKE--PAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYI 228 Query: 222 IAKQQAIKIETTSSKVESSSESYKIRVAK------------------------------R 251 +AK+ +E K S+S+ +R+ R Sbjct: 229 VAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSR 288 Query: 252 ERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPA-YIYEICCWSAYYNSAMNPLIY 310 E+KAAKTLG+ V F++ WLP+ + + + + L P ++++ W Y+NS +NP+IY Sbjct: 289 EKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIY 348 Query: 311 ALFYPWFRKAIKLIL 325 F++A IL Sbjct: 349 PCSSKEFKRAFVRIL 363 >gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sapiens] Length = 377 Score = 140 bits (354), Expect = 1e-33 Identities = 102/342 (29%), Positives = 164/342 (47%), Gaps = 55/342 (16%) Query: 31 RVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMV 90 ++ L S +L V N V+T++L ++LH+P N+LI SLA D LV + VM S+ Sbjct: 38 KISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIA 97 Query: 91 RTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGI 150 T+ W FG C + D+ C +S+LHLC I +DRY +TD L Y+ + T + Sbjct: 98 YTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAT 157 Query: 151 CISVSWILPLTYS-GAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPT 209 I++ W + + S +F+ EE+ L V QI + + F+IP+ Sbjct: 158 MIAIVWAISICISIPPLFWRQAK--AQEEMSDCL--VNTSQISYT---IYSTCGAFYIPS 210 Query: 210 LVMIILYSKIFLIAKQQAI-------KIETTSSKVESSSES------------------- 243 +++IILY +I+ A+ + + K TT+ + S+ S Sbjct: 211 VLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGS 270 Query: 244 ------YKIRV-----------AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMG-- 284 KI++ A RERKA K LG+ + AF+I WLP+ V L+ Sbjct: 271 PLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDS 330 Query: 285 -FLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 ++ PA +++ W Y NS +NP+IY +F FR+A + I+ Sbjct: 331 CWIHPA-LFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIV 371 >gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sapiens] Length = 366 Score = 139 bits (351), Expect = 3e-33 Identities = 104/348 (29%), Positives = 160/348 (45%), Gaps = 59/348 (16%) Query: 30 SRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSM 89 S++++ S +L+ N LV+ +++ ++LH P N+LI SLA DFLV V VM FS+ Sbjct: 22 SKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSI 81 Query: 90 VRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSG 149 V V W G C + D+ C S+LHL I +DRY +TD + YA K T +G Sbjct: 82 VYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAG 141 Query: 150 ICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPT 209 I I++ WI+ + S + ++ C+ IVS + F F+IP Sbjct: 142 IMITIVWIISVFISMPPLFWRHQGTSRDD-----ECIIKHDHIVST--IYSTFGAFYIPL 194 Query: 210 LVMIILYSKIF-----LIAKQQAIKI-----------ETTSSKVESSSESYKIRVA---- 249 +++ILY KI+ L K+QA +I E+ +S S SY + + Sbjct: 195 ALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDP 254 Query: 250 -------------------------------KRERKAAKTLGVTVLAFVISWLPYTV-DI 277 RERKAA TLG+ + AFVI WLP+ V ++ Sbjct: 255 STDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKEL 314 Query: 278 LIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 +++ + W Y NS +NPLIY +F F+KA + ++ Sbjct: 315 VVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLV 362 >gi|4503383 dopamine receptor D1 [Homo sapiens] Length = 446 Score = 139 bits (349), Expect = 5e-33 Identities = 106/342 (30%), Positives = 163/342 (47%), Gaps = 38/342 (11%) Query: 16 DVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSP-TNFLIASLA 74 D G +E +S R++ S L + GN LV +V+ F+ L S TNF + SLA Sbjct: 10 DGTGLVVERDFSV--RILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLA 67 Query: 75 CADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVT 134 +D LV V VM + V + W FG+ FC + D+ +S+L+LC I +DRY ++ Sbjct: 68 VSDLLVAVLVMPWKAVAEIAGFWPFGS-FCNIWVAFDIMCSTASILNLCVISVDRYWAIS 126 Query: 135 DPLVYATKFTVSVSGICISVSWIL-------PLTYSGAVFYTGVNDDGLEELVSALNCVG 187 P Y K T + I ISV+W L P+ S DG S + Sbjct: 127 SPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDG--NATSLAETID 184 Query: 188 GCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKI-------------ETT 233 C +S+ + + ++ F+IP +MI+ Y++I+ IA++Q +I +TT Sbjct: 185 NCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTT 244 Query: 234 SSK---VESSSESYKIRVA-KRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMG----- 284 + VE S +++ KRE K KTL V + FV WLP+ + I F G Sbjct: 245 TGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQ 304 Query: 285 -FLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 F + +++ W + NS++NP+IYA F FRKA +L Sbjct: 305 PFCIDSNTFDVFVWFGWANSSLNPIIYA-FNADFRKAFSTLL 345 >gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] Length = 432 Score = 135 bits (341), Expect = 4e-32 Identities = 103/347 (29%), Positives = 154/347 (44%), Gaps = 48/347 (13%) Query: 15 EDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLA 74 ++ +G + Y +V++ + + +LL + GN LV+ SV K+L P+N+LI SLA Sbjct: 65 DNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLA 124 Query: 75 CADFLVGVTVMLF-SMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV 133 AD V V VM F S+ + W FG FC + DV C +S++ LC I IDRY+ + Sbjct: 125 LADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI 184 Query: 134 TDPLVYATKFTVSVSGICISVSWILPLTYSGAVFY---TGVNDDGLEELVSALNCVGGCQ 190 T PL Y + I W+L + + + VNDD + C Sbjct: 185 TRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKV------------CL 232 Query: 191 IIVSQGWVLID-FLLFFIPTLVMIILYSKIFLIAKQQAIK-------------------I 230 I G+ + + F+IP VM+ +Y +I+ A++ A K I Sbjct: 233 ISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGI 292 Query: 231 ETTSSKVESSS--------ESYKIRVAKRERKAAKTLGVTVLAFVISWLPY----TVDIL 278 +VE + E I + KRE+KAA TLG+ V AF + WLP+ T Sbjct: 293 VKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPF 352 Query: 279 IDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 I P ++ W Y NS +NP IYA F R + +L Sbjct: 353 ICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL 399 >gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] Length = 479 Score = 135 bits (341), Expect = 4e-32 Identities = 103/347 (29%), Positives = 154/347 (44%), Gaps = 48/347 (13%) Query: 15 EDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLA 74 ++ +G + Y +V++ + + +LL + GN LV+ SV K+L P+N+LI SLA Sbjct: 65 DNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLA 124 Query: 75 CADFLVGVTVMLF-SMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV 133 AD V V VM F S+ + W FG FC + DV C +S++ LC I IDRY+ + Sbjct: 125 LADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI 184 Query: 134 TDPLVYATKFTVSVSGICISVSWILPLTYSGAVFY---TGVNDDGLEELVSALNCVGGCQ 190 T PL Y + I W+L + + + VNDD + C Sbjct: 185 TRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKV------------CL 232 Query: 191 IIVSQGWVLID-FLLFFIPTLVMIILYSKIFLIAKQQAIK-------------------I 230 I G+ + + F+IP VM+ +Y +I+ A++ A K I Sbjct: 233 ISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGI 292 Query: 231 ETTSSKVESSS--------ESYKIRVAKRERKAAKTLGVTVLAFVISWLPY----TVDIL 278 +VE + E I + KRE+KAA TLG+ V AF + WLP+ T Sbjct: 293 VKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPF 352 Query: 279 IDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 I P ++ W Y NS +NP IYA F R + +L Sbjct: 353 ICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL 399 >gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] Length = 445 Score = 135 bits (341), Expect = 4e-32 Identities = 103/347 (29%), Positives = 154/347 (44%), Gaps = 48/347 (13%) Query: 15 EDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLA 74 ++ +G + Y +V++ + + +LL + GN LV+ SV K+L P+N+LI SLA Sbjct: 65 DNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLA 124 Query: 75 CADFLVGVTVMLF-SMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV 133 AD V V VM F S+ + W FG FC + DV C +S++ LC I IDRY+ + Sbjct: 125 LADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI 184 Query: 134 TDPLVYATKFTVSVSGICISVSWILPLTYSGAVFY---TGVNDDGLEELVSALNCVGGCQ 190 T PL Y + I W+L + + + VNDD + C Sbjct: 185 TRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKV------------CL 232 Query: 191 IIVSQGWVLID-FLLFFIPTLVMIILYSKIFLIAKQQAIK-------------------I 230 I G+ + + F+IP VM+ +Y +I+ A++ A K I Sbjct: 233 ISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGI 292 Query: 231 ETTSSKVESSS--------ESYKIRVAKRERKAAKTLGVTVLAFVISWLPY----TVDIL 278 +VE + E I + KRE+KAA TLG+ V AF + WLP+ T Sbjct: 293 VKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPF 352 Query: 279 IDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325 I P ++ W Y NS +NP IYA F R + +L Sbjct: 353 ICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL 399 >gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] Length = 572 Score = 134 bits (336), Expect = 2e-31 Identities = 91/318 (28%), Positives = 149/318 (46%), Gaps = 43/318 (13%) Query: 43 LLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAK 102 L+AV GNLLV+ SV + L + TN+ I +LA AD L+ TV+ FS V W FG Sbjct: 108 LMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRA 167 Query: 103 FCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTY 162 FC + + DV C +S+L LC I +DRY+ V L Y T + +++ W++ L Sbjct: 168 FCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVV 227 Query: 163 SGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFL 221 S G +E V C I G+ + + F++P V++++Y ++++ Sbjct: 228 SVGPLL------GWKEPVPPDERF--CGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYV 279 Query: 222 IAKQQAIKIET-------------------------------TSSKVESSSESYKIRVAK 250 +A+ +E S+K + S +R+ K Sbjct: 280 VARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLK 339 Query: 251 --RERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAY-IYEICCWSAYYNSAMNP 307 RE+KAAKTL + V FV+ W P+ + + + L P+ ++++ W Y+NS +NP Sbjct: 340 FSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNP 399 Query: 308 LIYALFYPWFRKAIKLIL 325 LIY F++A +L Sbjct: 400 LIYPCSSREFKRAFLRLL 417 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.329 0.140 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,139,056 Number of Sequences: 37866 Number of extensions: 431334 Number of successful extensions: 2919 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 432 Number of HSP's successfully gapped in prelim test: 270 Number of HSP's that attempted gapping in prelim test: 1520 Number of HSP's gapped (non-prelim): 897 length of query: 342 length of database: 18,247,518 effective HSP length: 103 effective length of query: 239 effective length of database: 14,347,320 effective search space: 3429009480 effective search space used: 3429009480 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.