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Search of human proteins with 167466260
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466260 membrane-spanning 4-domains, subfamily A, member
10 [Homo sapiens]
(267 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10... 547 e-156
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ... 67 2e-11
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15... 56 4e-08
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [... 53 2e-07
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [... 53 2e-07
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [... 53 2e-07
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [... 47 1e-05
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ... 47 2e-05
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is... 47 2e-05
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ... 42 7e-04
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 40 0.002
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ... 39 0.005
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ... 39 0.005
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ... 39 0.005
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ... 39 0.005
gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ... 39 0.005
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i... 39 0.005
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i... 39 0.005
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i... 36 0.031
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i... 36 0.040
gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ... 36 0.040
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i... 36 0.040
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14... 33 0.20
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] 31 1.3
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] 31 1.3
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] 31 1.3
gi|7706693 membrane-bound transcription factor peptidase, site 2... 30 1.7
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A... 30 2.2
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A... 30 2.2
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A... 30 2.2
>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
[Homo sapiens]
Length = 267
Score = 547 bits (1410), Expect = e-156
Identities = 267/267 (100%), Positives = 267/267 (100%)
Query: 1 MKAEATVIPSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQKKSSLLKEL 60
MKAEATVIPSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQKKSSLLKEL
Sbjct: 1 MKAEATVIPSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQKKSSLLKEL 60
Query: 61 GAFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYL 120
GAFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYL
Sbjct: 61 GAFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYL 120
Query: 121 KMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALLCFTVL 180
KMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALLCFTVL
Sbjct: 121 KMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALLCFTVL 180
Query: 181 ELFLPVPTAVTAWRGDCPSAKNDDACLVPNTPLHLKGLPVEPPPSYQSVIQGDAQHKQHQ 240
ELFLPVPTAVTAWRGDCPSAKNDDACLVPNTPLHLKGLPVEPPPSYQSVIQGDAQHKQHQ
Sbjct: 181 ELFLPVPTAVTAWRGDCPSAKNDDACLVPNTPLHLKGLPVEPPPSYQSVIQGDAQHKQHQ 240
Query: 241 RLREVKQVAPDTWIVTDGAAIWTQTAN 267
RLREVKQVAPDTWIVTDGAAIWTQTAN
Sbjct: 241 RLREVKQVAPDTWIVTDGAAIWTQTAN 267
>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
[Homo sapiens]
Length = 250
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/227 (26%), Positives = 100/227 (44%), Gaps = 20/227 (8%)
Query: 21 VLSPVQPWQTSAPQ----NTTQPKLLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGG 76
++S V + S PQ P L++ + QK K LGA I I L H+ G
Sbjct: 29 IMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQPVQKALKEGKTLGAIQIIIGLAHIGLGS 88
Query: 77 YLASIVKNLHLVV-LKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMT-----NLI 130
+A+++ +L + +PFWG F+ISG L++ + +Y CL++ N++
Sbjct: 89 IMATVLVGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSY----CLLSGSLGLNIV 144
Query: 131 SLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALLCFTVLELFLPVPTAV 190
S C G+ + DL + P+ P + Y + LL F +LE + ++
Sbjct: 145 SAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVNPGMAISGVLLVFCLLEFGIACASSH 204
Query: 191 TAWRGDCPSAKNDDACLVPN----TPLHLKGLPVEPPPSYQSVIQGD 233
+ C + N + + PN P+ + PV PPSY S IQ +
Sbjct: 205 FGCQLVCCQSSN-VSVIYPNIYAANPV-ITPEPVTSPPSYSSEIQAN 249
>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
isoform 1 [Homo sapiens]
Length = 240
Score = 55.8 bits (133), Expect = 4e-08
Identities = 49/180 (27%), Positives = 79/180 (43%), Gaps = 26/180 (14%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVK-NLHLVVLKSWYPFWGAASFLISGILAITMKTFS 116
K LG I I L+HL FG L + + ++ + ++ PFWG A F+ISG L++ +
Sbjct: 72 KVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNH 131
Query: 117 KTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALL- 175
+ L L TN++S+ +G ++ D + + + R LA+L
Sbjct: 132 TSCLVRSSLGTNILSVMAAFAGTAILLMD--------------FGVTNRDVDRGYLAVLT 177
Query: 176 CFTVLELFLPVPTAVTAWRGDCP---SAKNDDACLVPN---TPLHLKGLPVEPPPSYQSV 229
FTVLE F TAV A C + + +PN ++ PP+Y +V
Sbjct: 178 IFTVLEFF----TAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNV 233
>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 53.1 bits (126), Expect = 2e-07
Identities = 32/90 (35%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISG-ILAITMKTFS 116
K LGA I L H+ GG L + + WYP WG ++ISG +LA T K
Sbjct: 50 KTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSR 109
Query: 117 KTYLKMLCLMTNLISLFCVLSGLFVISKDL 146
K +K +M N +SLF +SG+ + D+
Sbjct: 110 KCLVKGKMIM-NSLSLFAAISGMILSIMDI 138
>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 53.1 bits (126), Expect = 2e-07
Identities = 32/90 (35%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISG-ILAITMKTFS 116
K LGA I L H+ GG L + + WYP WG ++ISG +LA T K
Sbjct: 50 KTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSR 109
Query: 117 KTYLKMLCLMTNLISLFCVLSGLFVISKDL 146
K +K +M N +SLF +SG+ + D+
Sbjct: 110 KCLVKGKMIM-NSLSLFAAISGMILSIMDI 138
>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
[Homo sapiens]
Length = 267
Score = 53.1 bits (126), Expect = 2e-07
Identities = 44/174 (25%), Positives = 72/174 (41%), Gaps = 16/174 (9%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNLHLVV------LKSWYPFWGAASFLISGILAIT 111
K LG I + L+H+ FG L I + V+ + YPFWG SF+ISG L+++
Sbjct: 89 KALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGSLSVS 148
Query: 112 MKTFSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLE 171
L L N++S G+ ++ D+ + W + + +
Sbjct: 149 ASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAGQDYWAVLSG-----KGIS 203
Query: 172 LALLCFTVLELFLPVPTAVTAWRGDCPSAKNDDACLVPNTPLHLKGLPVEPPPS 225
L+ F++LE F+ TA A + N ++PN + PV P S
Sbjct: 204 ATLMIFSLLEFFVACATAHFA--NQANTTTNMSVLVIPNM---YESNPVTPASS 252
>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
[Homo sapiens]
Length = 200
Score = 47.4 bits (111), Expect = 1e-05
Identities = 35/142 (24%), Positives = 69/142 (48%), Gaps = 10/142 (7%)
Query: 57 LKELGAFHITIALLHLVFGG-YLASIVKNLHLV--VLKSWYPFWGAASFLISGILAITMK 113
+K LG I ++ FG +L +++K + S YPFWG+ F+ SG I +K
Sbjct: 47 MKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVK 106
Query: 114 TFSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNS-----TVHIQ 168
+ L +L + N +S ++G+ +++ L+ + + NS TV
Sbjct: 107 RKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNYICGY--SHQNSQCKAVTVLFL 164
Query: 169 RLELALLCFTVLELFLPVPTAV 190
+ + L+ F+++ELF+ +P ++
Sbjct: 165 GILITLMTFSIIELFISLPFSI 186
>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
isoform 2 [Homo sapiens]
Length = 195
Score = 46.6 bits (109), Expect = 2e-05
Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 9/120 (7%)
Query: 32 APQNTTQPKLLAPHQHEKSQKKSSLLKE----LGAFHITIALLHLVFGGYLASIVKNLHL 87
+PQ + +LL ++LK+ LG I A++ L FG + S++ H+
Sbjct: 29 SPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHI 88
Query: 88 V-----VLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142
K+ YPFWGA F ISG+L+I + + TYL L N S +G+ ++
Sbjct: 89 EGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148
>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
isoform 1 [Homo sapiens]
Length = 244
Score = 46.6 bits (109), Expect = 2e-05
Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 9/120 (7%)
Query: 32 APQNTTQPKLLAPHQHEKSQKKSSLLKE----LGAFHITIALLHLVFGGYLASIVKNLHL 87
+PQ + +LL ++LK+ LG I A++ L FG + S++ H+
Sbjct: 29 SPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHI 88
Query: 88 V-----VLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142
K+ YPFWGA F ISG+L+I + + TYL L N S +G+ ++
Sbjct: 89 EGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148
>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
isoform 2 [Homo sapiens]
Length = 147
Score = 41.6 bits (96), Expect = 7e-04
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 25/142 (17%)
Query: 95 PFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFES 154
PFWG A F+ISG L++ + + L L TN++S+ +G ++ D
Sbjct: 17 PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD--------- 67
Query: 155 PIWRMYPNSTVHIQRLELALL-CFTVLELFLPVPTAVTAWRGDCP---SAKNDDACLVPN 210
+ + + R LA+L FTVLE F TAV A C + + +PN
Sbjct: 68 -----FGVTNRDVDRGYLAVLTIFTVLEFF----TAVIAMHFGCQAIHAQASAPVIFLPN 118
Query: 211 ---TPLHLKGLPVEPPPSYQSV 229
++ PP+Y +V
Sbjct: 119 AFSADFNIPSPAASAPPAYDNV 140
>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
isoform 1 [Homo sapiens]
Length = 679
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/58 (43%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 60 LGAFHITIALLHLVFGGYLA----SIVKNLHLVVLKSWYPFWGAASFLISGILAITMK 113
LGA I +AL+ + FG A + L LVVL YPFWGA F+++G L +T K
Sbjct: 45 LGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTG-YPFWGALIFILTGYLTVTDK 101
>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Query: 62 AFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLK 121
A I I L H+ + ++ V S YP WG S+++SG L++ +
Sbjct: 151 AIQILIGLTHIFSA--INPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVV 208
Query: 122 MLCLMTNLISLFCVLSGLFVISKDLFL 148
+ N+IS +G+F+I DL L
Sbjct: 209 NSSISFNIISALFAFAGIFIIITDLSL 235
>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Query: 62 AFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLK 121
A I I L H+ + ++ V S YP WG S+++SG L++ +
Sbjct: 151 AIQILIGLTHIFSA--INPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVV 208
Query: 122 MLCLMTNLISLFCVLSGLFVISKDLFL 148
+ N+IS +G+F+I DL L
Sbjct: 209 NSSISFNIISALFAFAGIFIIITDLSL 235
>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Query: 62 AFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLK 121
A I I L H+ + ++ V S YP WG S+++SG L++ +
Sbjct: 151 AIQILIGLTHIFSA--INPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVV 208
Query: 122 MLCLMTNLISLFCVLSGLFVISKDLFL 148
+ N+IS +G+F+I DL L
Sbjct: 209 NSSISFNIISALFAFAGIFIIITDLSL 235
>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
isoform 2 [Homo sapiens]
Length = 225
Score = 38.9 bits (89), Expect = 0.005
Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 37/195 (18%)
Query: 29 QTSAPQNTTQPK-LLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGGYLASI-----V 82
Q P+ T Q + L H H + +K +G I ++ L G LAS
Sbjct: 23 QAEKPEPTNQGQDSLKKHLHAE-------IKVIGTIQILCGMMVLSLGIILASASFSPNF 75
Query: 83 KNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142
+ +L S YPF G F+ISG L+I + L L+ +++S L G ++
Sbjct: 76 TQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
Query: 143 S-KDLFLES------------PFESPIWRMYPNSTVHIQ----------RLELALLCFTV 179
S K L P S + Y +S L L L+C T+
Sbjct: 136 SVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLIC-TL 194
Query: 180 LELFLPVPTAVTAWR 194
LE L V TAV W+
Sbjct: 195 LEFCLAVLTAVLRWK 209
>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
isoform 1 [Homo sapiens]
Length = 248
Score = 38.9 bits (89), Expect = 0.005
Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 37/195 (18%)
Query: 29 QTSAPQNTTQPK-LLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGGYLASI-----V 82
Q P+ T Q + L H H + +K +G I ++ L G LAS
Sbjct: 23 QAEKPEPTNQGQDSLKKHLHAE-------IKVIGTIQILCGMMVLSLGIILASASFSPNF 75
Query: 83 KNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142
+ +L S YPF G F+ISG L+I + L L+ +++S L G ++
Sbjct: 76 TQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
Query: 143 S-KDLFLES------------PFESPIWRMYPNSTVHIQ----------RLELALLCFTV 179
S K L P S + Y +S L L L+C T+
Sbjct: 136 SVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLIC-TL 194
Query: 180 LELFLPVPTAVTAWR 194
LE L V TAV W+
Sbjct: 195 LEFCLAVLTAVLRWK 209
>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 38.9 bits (89), Expect = 0.005
Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 26/161 (16%)
Query: 60 LGAFHITIALLHLVFGGYLASIVKNLHL-----VVLKSWYPFWGAASFLISGILAITMKT 114
LG I LL G L H L S YPF GA F I+G L+I
Sbjct: 48 LGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGK 107
Query: 115 FSKTYLKMLCLMTNLISLFCVLSGLFVISKDL---------------FLES-PFESPIWR 158
S + L +N +S +GLF+++ + +L S P+ +
Sbjct: 108 QSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYP 167
Query: 159 MYP-----NSTVHIQRLELALLCFTVLELFLPVPTAVTAWR 194
+Y ++V + + + +L FTVLEL L ++V W+
Sbjct: 168 IYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWK 208
>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 38.9 bits (89), Expect = 0.005
Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 26/161 (16%)
Query: 60 LGAFHITIALLHLVFGGYLASIVKNLHL-----VVLKSWYPFWGAASFLISGILAITMKT 114
LG I LL G L H L S YPF GA F I+G L+I
Sbjct: 48 LGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGK 107
Query: 115 FSKTYLKMLCLMTNLISLFCVLSGLFVISKDL---------------FLES-PFESPIWR 158
S + L +N +S +GLF+++ + +L S P+ +
Sbjct: 108 QSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYP 167
Query: 159 MYP-----NSTVHIQRLELALLCFTVLELFLPVPTAVTAWR 194
+Y ++V + + + +L FTVLEL L ++V W+
Sbjct: 168 IYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWK 208
>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
isoform a [Homo sapiens]
Length = 214
Score = 36.2 bits (82), Expect = 0.031
Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 18/162 (11%)
Query: 57 LKELGAFHITIALLHLVFGGYLASIV------KNLHLVVLKSWYPFWGAASFLISGILAI 110
L+ LGA I A + L G +L S+ K+ + YP WGA F SG L++
Sbjct: 48 LQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFFTFYTGYPIWGAVFFCSSGTLSV 107
Query: 111 TMKTF-SKTYLKMLCLMTNLISLFCVLSGLFVISKDLFL--------ESPFESPIWRMYP 161
++T+++ M N+ S L G +S ++ + S ESP Y
Sbjct: 108 VAGIKPTRTWIQNSFGM-NIASATIALVGTAFLSLNIAVNIQSLRSCHSSSESPDLCNYM 166
Query: 162 NSTVHIQRLELALLCFTVLELFLPVPTAVTAWRGDCPSAKND 203
S + + LL T+LEL + + T +C +++ +
Sbjct: 167 GSISN--GMVSLLLILTLLELCVTISTIAMWCNANCCNSREE 206
>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
isoform a [Homo sapiens]
Length = 220
Score = 35.8 bits (81), Expect = 0.040
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 10/138 (7%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNLH---LVVLKSWYPFWGAASFLISGILAITMKT 114
K LG I AL+ L G + + N + + + Y WG+ F+ISG L+I
Sbjct: 45 KVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGI 104
Query: 115 FSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNS-TVH-----IQ 168
+ L L N+ S SG+ + + L S F P Y NS H +
Sbjct: 105 RTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYS-FHHPYCNYYGNSNNCHGTMSILM 163
Query: 169 RLELALLCFTVLELFLPV 186
L+ +L +VLE + V
Sbjct: 164 GLDGMVLLLSVLEFCIAV 181
>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
isoform 3 [Homo sapiens]
Length = 178
Score = 35.8 bits (81), Expect = 0.040
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 13/121 (10%)
Query: 29 QTSAPQNTTQPK-LLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGGYLASI-----V 82
Q P+ T Q + L H H + +K +G I ++ L G LAS
Sbjct: 23 QAEKPEPTNQGQDSLKKHLHAE-------IKVIGTIQILCGMMVLSLGIILASASFSPNF 75
Query: 83 KNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142
+ +L S YPF G F+ISG L+I + L L+ +++S L G ++
Sbjct: 76 TQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
Query: 143 S 143
S
Sbjct: 136 S 136
>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
isoform b [Homo sapiens]
Length = 239
Score = 35.8 bits (81), Expect = 0.040
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 10/138 (7%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNLH---LVVLKSWYPFWGAASFLISGILAITMKT 114
K LG I AL+ L G + + N + + + Y WG+ F+ISG L+I
Sbjct: 64 KVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGI 123
Query: 115 FSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNS-TVH-----IQ 168
+ L L N+ S SG+ + + L S F P Y NS H +
Sbjct: 124 RTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYS-FHHPYCNYYGNSNNCHGTMSILM 182
Query: 169 RLELALLCFTVLELFLPV 186
L+ +L +VLE + V
Sbjct: 183 GLDGMVLLLSVLEFCIAV 200
>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
isoform 2 [Homo sapiens]
Length = 662
Score = 33.5 bits (75), Expect = 0.20
Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 15/97 (15%)
Query: 60 LGAFHITIALLHLVFGGYLA----SIVKNLHLVVLKSWYPFWGA-------ASFLISGIL 108
LGA I +AL+ + FG A + L LVVL YPFWGA +IS ++
Sbjct: 45 LGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTG-YPFWGALIGQGVTGMNVISSLV 103
Query: 109 AITMKTF---SKTYLKMLCLMTNLISLFCVLSGLFVI 142
AIT TF S + C M + + LF++
Sbjct: 104 AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIV 140
>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
Length = 2365
Score = 30.8 bits (68), Expect = 1.3
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 8/43 (18%)
Query: 9 PSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQ 51
PS+C G P QV PV PQ QP APHQ K+Q
Sbjct: 153 PSQCQAGTPQQQV--PV------TPQAPCQPHQPAPHQQSKAQ 187
>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
Length = 2432
Score = 30.8 bits (68), Expect = 1.3
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 8/43 (18%)
Query: 9 PSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQ 51
PS+C G P QV PV PQ QP APHQ K+Q
Sbjct: 217 PSQCQAGTPQQQV--PV------TPQAPCQPHQPAPHQQSKAQ 251
>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
Length = 2429
Score = 30.8 bits (68), Expect = 1.3
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 8/43 (18%)
Query: 9 PSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQ 51
PS+C G P QV PV PQ QP APHQ K+Q
Sbjct: 217 PSQCQAGTPQQQV--PV------TPQAPCQPHQPAPHQQSKAQ 251
>gi|7706693 membrane-bound transcription factor peptidase, site 2
[Homo sapiens]
Length = 519
Score = 30.4 bits (67), Expect = 1.7
Identities = 24/109 (22%), Positives = 40/109 (36%), Gaps = 12/109 (11%)
Query: 140 FVISKDLFLESPFESPIWRMYPNSTVHIQRLELALLCFTVLELF-------LPVPTAVTA 192
+ IS + F ++ ST L +CF+ F LP AV A
Sbjct: 308 YCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEA 367
Query: 193 WR-----GDCPSAKNDDACLVPNTPLHLKGLPVEPPPSYQSVIQGDAQH 236
+ DC + + C++P+ H + + V+ PP + G H
Sbjct: 368 TQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLH 416
>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 1 [Homo sapiens]
Length = 243
Score = 30.0 bits (66), Expect = 2.2
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNL---HLVVLKSWYPFWGAASFLISGILAITMKT 114
K LG I IAL+ L G + + + H + + Y WG+ F+IS L++
Sbjct: 68 KVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISVSLSVAAGI 127
Query: 115 FSKTYLKMLCLMTNLISLFCVLSGLFV 141
+ L L N+ S +SG+ +
Sbjct: 128 RTTKGLVGGSLGKNITSSVLAISGILI 154
>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 30.0 bits (66), Expect = 2.2
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNL---HLVVLKSWYPFWGAASFLISGILAITMKT 114
K LG I IAL+ L G + + + H + + Y WG+ F+IS L++
Sbjct: 68 KVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISVSLSVAAGI 127
Query: 115 FSKTYLKMLCLMTNLISLFCVLSGLFV 141
+ L L N+ S +SG+ +
Sbjct: 128 RTTKGLVGGSLGKNITSSVLAISGILI 154
>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 30.0 bits (66), Expect = 2.2
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 58 KELGAFHITIALLHLVFGGYLASIVKNL---HLVVLKSWYPFWGAASFLISGILAITMKT 114
K LG I IAL+ L G + + + H + + Y WG+ F+IS L++
Sbjct: 68 KVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISVSLSVAAGI 127
Query: 115 FSKTYLKMLCLMTNLISLFCVLSGLFV 141
+ L L N+ S +SG+ +
Sbjct: 128 RTTKGLVGGSLGKNITSSVLAISGILI 154
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,930,600
Number of Sequences: 37866
Number of extensions: 492972
Number of successful extensions: 1489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1457
Number of HSP's gapped (non-prelim): 39
length of query: 267
length of database: 18,247,518
effective HSP length: 100
effective length of query: 167
effective length of database: 14,460,918
effective search space: 2414973306
effective search space used: 2414973306
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.