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Search of human proteins with 167000751
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167000751 gamma-aminobutyric acid A receptor, alpha 2
precursor [Homo sapiens]
(451 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 913 0.0
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 913 0.0
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 689 0.0
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 689 0.0
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 689 0.0
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 689 0.0
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 689 0.0
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 689 0.0
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 689 0.0
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 659 0.0
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 640 0.0
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 499 e-141
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 477 e-134
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 362 e-100
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 360 1e-99
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 360 2e-99
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 341 7e-94
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 340 2e-93
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 293 2e-79
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 283 3e-76
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 280 2e-75
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 280 2e-75
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 280 2e-75
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 279 3e-75
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 276 2e-74
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 276 2e-74
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 276 3e-74
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 276 3e-74
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 276 4e-74
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 275 6e-74
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 913 bits (2360), Expect = 0.0
Identities = 451/451 (100%), Positives = 451/451 (100%)
Query: 1 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 60
MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
Sbjct: 1 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 60
Query: 61 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 120
LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
Sbjct: 61 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 180
Query: 181 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 240
PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
Sbjct: 181 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 240
Query: 241 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 360
Query: 361 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 420
MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
Sbjct: 361 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 420
Query: 421 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 451
SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
Sbjct: 421 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 451
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 913 bits (2360), Expect = 0.0
Identities = 451/451 (100%), Positives = 451/451 (100%)
Query: 1 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 60
MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
Sbjct: 1 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 60
Query: 61 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 120
LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
Sbjct: 61 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 180
Query: 181 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 240
PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
Sbjct: 181 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 240
Query: 241 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 360
Query: 361 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 420
MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
Sbjct: 361 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 420
Query: 421 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 451
SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
Sbjct: 421 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 451
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 659 bits (1701), Expect = 0.0
Identities = 323/419 (77%), Positives = 359/419 (85%), Gaps = 5/419 (1%)
Query: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
+DE +NITIFTRILD LLDGYDNRLRPGLG+ IT+V T+IYVTSFGPVSDT+MEYTIDV
Sbjct: 39 KDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDV 98
Query: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
FFRQ WKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR++DD
Sbjct: 99 FFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDD 158
Query: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
GTLLYTMRLT+ AECPM LEDFPMDAH+CPLKFGSYAY SEV Y+WT ++ SV VA D
Sbjct: 159 GTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAED 218
Query: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQY L+GQ++G E I +STGEYT+MTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 219 GSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 278
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 279 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 338
Query: 332 ATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQN---NAYAVAVANYAPNLSKDPVLSTIS 388
ATVNYFTKRGWAWDGK + K +K +I N NA+ ++ PN+ K+ +
Sbjct: 339 ATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQ--TPAG 396
Query: 389 KSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
S TT K E K +E+KKT+NS+SKID+MSRIVFPVLFGTFNLVYWATYLNREPV+
Sbjct: 397 TSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 640 bits (1651), Expect = 0.0
Identities = 321/429 (74%), Positives = 352/429 (82%), Gaps = 15/429 (3%)
Query: 33 DEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVF 92
D++ +NITIFTRILDRLLDGYDNRLRPGLGD++TEV T+IYVTSFGPVSDTDMEYTIDVF
Sbjct: 58 DDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVF 117
Query: 93 FRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDG 152
FRQ W DERLKF GPM IL LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+ D+G
Sbjct: 118 FRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNG 177
Query: 153 TLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDG 212
TLLYTMRLT+ AECPMHLEDFPMD H+CPLKFGSYAYTT+EV Y WT + SV+VA DG
Sbjct: 178 TLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDG 237
Query: 213 SRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSF 272
SRLNQYDLLG +G E I+SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVSF
Sbjct: 238 SRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSF 297
Query: 273 WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA 332
WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA
Sbjct: 298 WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA 357
Query: 333 TVNYFTKRGWAWDGKSVVN----DKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTIS 388
TVNYFTKR WAW+GK V KK A + + + Y NL+KD STIS
Sbjct: 358 TVNYFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTIS 417
Query: 389 KSA-----TTPEPNKKP-----ENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWA 438
K A +TP P ++ P E KT+NSVSK+D++SRI+FPVLF FNLVYWA
Sbjct: 418 KGAAPSASSTPTIIASPKATYVQDSPTET-KTYNSVSKVDKISRIIFPVLFAIFNLVYWA 476
Query: 439 TYLNREPVL 447
TY+NRE +
Sbjct: 477 TYVNRESAI 485
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 499 bits (1285), Expect = e-141
Identities = 256/424 (60%), Positives = 300/424 (70%), Gaps = 34/424 (8%)
Query: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
+RILD LL+GYDNRLRPG G ++TEV T+IYVTSFGPVSD +MEYT+DVFFRQ W DERL
Sbjct: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
Query: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
KF GP IL LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI +GT+LYTMRLT+
Sbjct: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
Query: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLG 222
A+CPM L +FPMD H+CPLKFGSYAY SE+ Y W SV+V + S L QYDL+G
Sbjct: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
Query: 223 QSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Q++ ETIKS+TGEY +MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
Query: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 342
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT---- 328
Query: 343 AWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISK--------SATTP 394
++ K K KA V ++ L + VL SK S + P
Sbjct: 329 -----NLQTQKAKRKAQFAAPP---TVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLP 380
Query: 395 EPNKKPENK--------------PAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
+ NK P F SKID+ SRI+FPV F FNLVYW Y
Sbjct: 381 IVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
Query: 441 LNRE 444
L+++
Sbjct: 441 LSKD 444
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 477 bits (1227), Expect = e-134
Identities = 225/297 (75%), Positives = 257/297 (86%)
Query: 42 FTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDER 101
FTRILD LLDGYDNRLRPG G +TEV T+IYVTSFGPVSD +MEYT+DVFFRQ W D+R
Sbjct: 48 FTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKR 107
Query: 102 LKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
LK+ GP+ ILRLNN+M +K+WTPDTFF NGKKSV+HNMT PNKL RI +GT+LYTMRLT
Sbjct: 108 LKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLT 167
Query: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
+ AECPM L DFPMD H+CPLKFGSYAY SE+ Y WT SV+V + S L QYDL+
Sbjct: 168 ISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLI 227
Query: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
GQ++ ETIKS TGEY VMT +FHL+RK+GYF+IQTY+PCIMTVILSQVSFW+N+ESVPA
Sbjct: 228 GQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPA 287
Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT 338
RTVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 288 RTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT 344
Score = 50.8 bits (120), Expect = 2e-06
Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 384 LSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNR 443
+ K + TP P+ P + + SKID+ +RI+FPV FG FN+VYW YL++
Sbjct: 493 IGATGKLSATPPPSAPPPSG--------SGTSKIDKYARILFPVTFGAFNMVYWVVYLSK 544
Query: 444 E 444
+
Sbjct: 545 D 545
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 362 bits (930), Expect = e-100
Identities = 190/422 (45%), Positives = 265/422 (62%), Gaps = 38/422 (9%)
Query: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
T IL+ LL+GYDN+LRP +G T + T++YV S GPV+ +MEYTID+FF Q W D RL
Sbjct: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
Query: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
KF + +LRLN+ M KIW PDTFF N KK+ AH +T PN++LRI +DG +LYT+RLT+
Sbjct: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
Query: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-RLNQYDLL 221
AEC + L +FPMD HSCPL+F SY Y E+ Y W SV+V S RL Q+ +
Sbjct: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFV 243
Query: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
G E +K+++G+Y VM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPA
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF
Sbjct: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV--- 360
Query: 342 WAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATT--PEPNKK 399
+ DK K+K + +++ ++ AP + P +TI + T E +++
Sbjct: 361 ---SNRKPSKDKDKKKKNPLLRMFSFK------APTIDIRPRSATIQMNNATHLQERDEE 411
Query: 400 PENKPAEAK--------------------KTFNSVSKIDRMSRIVFPVLFGTFNLVYWAT 439
+ + K + ++K+D +RI FP F FNLVYW +
Sbjct: 412 YGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVS 471
Query: 440 YL 441
YL
Sbjct: 472 YL 473
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 360 bits (925), Expect = 1e-99
Identities = 196/419 (46%), Positives = 257/419 (61%), Gaps = 40/419 (9%)
Query: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
T+IL+ LL GYDN+LRP +G T + T++YV S GPV +MEYTID+ F Q W D RL
Sbjct: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
Query: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
KF M +L LN+ M KIW PDTFF N +KS AH +T PN+LLRI +DG +LYT+RLT+
Sbjct: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
Query: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVA-PDGSRLNQYDLL 221
AEC + L +FPMD HSCPL+F SY Y +E+ Y W SV+VA P RL Q+ +
Sbjct: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKW---KKPSVEVADPKYWRLYQFAFV 241
Query: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
G E + +G+Y +MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
Query: 342 WAWDGKSVVNDKK-KEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPN--- 397
GK+ D+K K KAS+ P L L ++ + E +
Sbjct: 361 --QKGKTATKDRKLKNKASM--------------TPGLHPGSTLIPMNNISVPQEDDYGY 404
Query: 398 KKPENKPAEA---------------KKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYL 441
+ E K + + ++KID SRI FP F FNLVYW YL
Sbjct: 405 QCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 360 bits (923), Expect = 2e-99
Identities = 191/422 (45%), Positives = 260/422 (61%), Gaps = 46/422 (10%)
Query: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
T IL+ LL+GYDN+LRP +G T + T++YV S GPV+ +MEYTID+FF Q W D RL
Sbjct: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
Query: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
KF + +LRLN+ M KIW PDTFF N KK+ AH +T PN++LRI +DG +LYT+RLT+
Sbjct: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
Query: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-RLNQYDLL 221
AEC + L +FPMD HSCPL+F SY Y E+ Y W SV+V S RL Q+ +
Sbjct: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFV 243
Query: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
G E +K+++G+Y VM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPA
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF
Sbjct: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV--- 360
Query: 342 WAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATT--PEPNKK 399
+ DK K+K N AP + P +TI + T E +++
Sbjct: 361 ---SNRKPSKDKDKKK--------------KNPAPTIDIRPRSATIQMNNATHLQERDEE 403
Query: 400 PENKPAEAK--------------------KTFNSVSKIDRMSRIVFPVLFGTFNLVYWAT 439
+ + K + ++K+D +RI FP F FNLVYW +
Sbjct: 404 YGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVS 463
Query: 440 YL 441
YL
Sbjct: 464 YL 465
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 341 bits (875), Expect = 7e-94
Identities = 189/462 (40%), Positives = 266/462 (57%), Gaps = 78/462 (16%)
Query: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
T IL+ LL+GYDN+LRP +G T + T++YV S GPV+ +MEYTID+FF Q W D RL
Sbjct: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
Query: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
KF + +LRLN+ M KIW PDTFF N KK+ AH +T PN++LRI +DG +LYT+RLT+
Sbjct: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
Query: 163 QAECPMHLEDFPMDAHSCPLKFGSYA---------------------------------- 188
AEC + L +FPMD HSCPL+F S++
Sbjct: 187 DAECQLQLHNFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRV 246
Query: 189 ------YTTSEVTYIWTYNASDSVQVAPDGS-RLNQYDLLGQSIGKETIKSSTGEYTVMT 241
Y E+ Y W SV+V S RL Q+ +G E +K+++G+Y VM+
Sbjct: 247 AGISDGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMS 303
Query: 242 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 301
+F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTVLTMTTLS AR
Sbjct: 304 VYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIAR 363
Query: 302 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVM 361
SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF + DK K+K + +
Sbjct: 364 KSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPSKDKDKKKKNPL 417
Query: 362 IQNNAYAVAVANYAPNLSKDPVLSTISKSATT--PEPNKKPENKPAEAK----------- 408
++ ++ AP + P +TI + T E +++ + + K
Sbjct: 418 LRMFSFK------APTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFED 471
Query: 409 ---------KTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYL 441
+ ++K+D +RI FP F FNLVYW +YL
Sbjct: 472 CRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 513
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 340 bits (872), Expect = 2e-93
Identities = 188/429 (43%), Positives = 252/429 (58%), Gaps = 27/429 (6%)
Query: 36 KNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQ 95
K+ T T IL++LL YD +LRP +G T + +IYV S GPVS +MEY ID+FF Q
Sbjct: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
Query: 96 KWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLL 155
W D RL+F M IL LN+ M IW PDT F N K + AH +T PN+LLRI +DG +L
Sbjct: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
Query: 156 YTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-R 214
YT+RLT+ AEC + L +FPMD HSCPL F SY Y E+ Y W N SV+ A S R
Sbjct: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKN---SVEAADQKSWR 217
Query: 215 LNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
L Q+D +G E + +S G+Y VMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
Query: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
Query: 335 NYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDP--VLSTISKSAT 392
NY++ K + + +S I A +NY+ + P + T++ S
Sbjct: 338 NYYSSCRKPTTTKKTTSLLHPD-SSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVY 396
Query: 393 TPEPNKKPENKPAEAK--------------------KTFNSVSKIDRMSRIVFPVLFGTF 432
E + + K + + ++D SR+ FP F F
Sbjct: 397 WQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLF 456
Query: 433 NLVYWATYL 441
NLVYW YL
Sbjct: 457 NLVYWVGYL 465
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 293 bits (750), Expect = 2e-79
Identities = 165/441 (37%), Positives = 242/441 (54%), Gaps = 48/441 (10%)
Query: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
+RIL+ +L YD++LRPG+G+ T V I V S GP+S DMEYTID+ F Q W DERL
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERL 131
Query: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
+ L LN + S++W PDTFF N K++ H +TMPN+++RI DG +LYT+R+T+
Sbjct: 132 CYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTI 191
Query: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-RLNQYDLL 221
A C +H+ FPMD+HSCPL F S++Y +E+ Y W + +++ S +L Q+D
Sbjct: 192 DAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKW---ENFKLEINEKNSWKLFQFDFT 248
Query: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
G S E I + G++ VMT F++ R+ GY Q Y+P +T +LS VSFW+ ES PA
Sbjct: 249 GVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPA 308
Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYF---- 337
RT G+T+VLTMTTL +R + P+V+Y TA+D++IA+C+ F F AL+EFA +N+
Sbjct: 309 RTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQ 368
Query: 338 TK-------RGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKS 390
TK R + ++ + + +A A+ + + ++ S S
Sbjct: 369 TKAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEE----RPSCS 424
Query: 391 ATTPEPNKKPENKPA--------EAKKTFNS---------------------VSKIDRMS 421
A P PE + E K F V ++D S
Sbjct: 425 AQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLDNYS 484
Query: 422 RIVFPVLFGTFNLVYWATYLN 442
R+VFPV F FN++YW LN
Sbjct: 485 RVVFPVTFFFFNVLYWLVCLN 505
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 283 bits (723), Expect = 3e-76
Identities = 162/416 (38%), Positives = 245/416 (58%), Gaps = 26/416 (6%)
Query: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
Query: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
+ P + L L+ M IW PD FF N K + H +T NKLLRI +G +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
Query: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
+ CPM L++FPMD +C ++ S+ YT +++ + W +VQVA DG L Q+ L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW--QEQGAVQVA-DGLTLPQFILK 218
Query: 222 GQSIGKETIKS-STGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
+ + K +TG++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
Query: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
Query: 341 GWAWDGKSVVNDKKK-------EKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATT 393
K ++ ++K E +AY + A +KD + + ++ T
Sbjct: 339 -----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQ---AKDGISVKGANNSNT 390
Query: 394 PEPNKKPENKPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY--LNREPV 446
P P P E +K F KID++SRI FP+ F FN+ YW Y + RE V
Sbjct: 391 TNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDV 446
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 280 bits (716), Expect = 2e-75
Identities = 153/446 (34%), Positives = 240/446 (53%), Gaps = 43/446 (9%)
Query: 37 NNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQK 96
+N++ +DRLL GYD RLRP G +V I V S VS+ +M+YT+ ++F+Q
Sbjct: 32 SNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQS 91
Query: 97 WKDERLKFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLL 155
WKD+RL + G P+N L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+L
Sbjct: 92 WKDKRLSYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVL 150
Query: 156 YTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRL 215
Y +R+T A C M L +P+D +C L+ SY YTT ++ + W N + + L
Sbjct: 151 YGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--NGGEGAVTGVNKIEL 208
Query: 216 NQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN 275
Q+ ++ + + ++ +TG Y ++ F LKR IGYF++QTY+P + ILS VSFW+N
Sbjct: 209 PQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWIN 268
Query: 276 RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN 335
++ AR G+TTVLTMTT+S R +LPK+ Y A+D ++ C+ FVF AL+E+A VN
Sbjct: 269 YDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVN 328
Query: 336 YF------TKRGWAWDGKSVVNDKKKEKASVMIQ-NNAYAVAVANYAPNLSKDPVLSTIS 388
Y K+G + +S K E V + + ++ S VL+++S
Sbjct: 329 YIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVS 388
Query: 389 KSATTP---EPNKKPENKPAEAKKTF-----------------------------NSVSK 416
T + KP +++ + V+
Sbjct: 389 DPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNS 448
Query: 417 IDRMSRIVFPVLFGTFNLVYWATYLN 442
ID+ SR+ FP+ F FN+VYW Y++
Sbjct: 449 IDKWSRMFFPITFSLFNVVYWLYYVH 474
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 280 bits (715), Expect = 2e-75
Identities = 162/424 (38%), Positives = 245/424 (57%), Gaps = 34/424 (8%)
Query: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
Query: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
+ P + L L+ M IW PD FF N K + H +T NKLLRI +G +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
Query: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
+ CPM L++FPMD +C ++ S+ YT +++ + W +VQVA DG L Q+ L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW--QEQGAVQVA-DGLTLPQFILK 218
Query: 222 GQSIGKETIKS-STGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
+ + K +TG++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
Query: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
Query: 341 GWAWDGKSVVNDKKK---------------EKASVMIQNNAYAVAVANYAPNLSKDPVLS 385
K ++ ++K E +AY + A +KD +
Sbjct: 339 -----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQ---AKDGISV 390
Query: 386 TISKSATTPEPNKKPENKPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY--LN 442
+ ++ T P P P E +K F KID++SRI FP+ F FN+ YW Y +
Sbjct: 391 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 450
Query: 443 REPV 446
RE V
Sbjct: 451 REDV 454
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 280 bits (715), Expect = 2e-75
Identities = 166/450 (36%), Positives = 257/450 (57%), Gaps = 31/450 (6%)
Query: 6 NIYNMQFLLFVFLVWDPARLV--LANIQEDEAKNNITIFTR--ILDRLL---DGYDNRLR 58
++ + + L+ F W+ A L+ +A + D A++ + LD+L+ GYD R+R
Sbjct: 3 HVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIR 62
Query: 59 PGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLM 117
P V NI++ SFG +++T M+Y +++F RQKW D RL + P + L L+ M
Sbjct: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSM 122
Query: 118 ASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDA 177
IW PD FF N K + H +T NKLLRI +G +LY++RLT+ CPM L++FPMD
Sbjct: 123 LDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDV 182
Query: 178 HSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS-STGE 236
+C ++ S+ YT +++ + W A VQVA +G L Q+ L + + K +TG+
Sbjct: 183 QTCIMQLESFGYTMNDLIFEWQDEAP--VQVA-EGLTLPQFLLKEEKDLRYCTKHYNTGK 239
Query: 237 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 296
+T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR G+TTVLTMTT
Sbjct: 240 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 299
Query: 297 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKE 356
S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++ K ++ ++K
Sbjct: 300 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-----HKELLRFRRKR 354
Query: 357 K-ASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKP----ENKPAEAKKTF 411
K ++ + ++ P L +K TP+ P P E +K F
Sbjct: 355 KNKDDEVRESRFSFTAYGMGPCLQ--------AKDGMTPKGPNHPVQVMPKSPDEMRKVF 406
Query: 412 -NSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
+ KID +SR FP+ F FN+ YW Y
Sbjct: 407 IDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 279 bits (714), Expect = 3e-75
Identities = 161/468 (34%), Positives = 250/468 (53%), Gaps = 45/468 (9%)
Query: 17 FLVWD-PARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVT 75
F +W P + Q +N+++ +DRLL GYD RLRP G V NI +
Sbjct: 10 FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIA 69
Query: 76 SFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLMASKIWTPDTFFHNGKKS 134
S VS+ +M+YT+ ++F+Q W+D+RL + P+N L L+N +A ++W PDT+F N KKS
Sbjct: 70 SIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKS 128
Query: 135 VAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEV 194
H +T+ N+++R+ DGT+LY +R+T A C M L +P+D +C L+ SY YTT ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 195 TYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFV 254
+ W D+ L Q+ ++ + + + STG Y ++ F LKR IGYF+
Sbjct: 189 EFYW--RGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFI 246
Query: 255 IQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD 314
+QTY+P I+ ILS VSFW+N ++ AR G+TTVLTMTT++ R +LPK+ Y A+D
Sbjct: 247 LQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAID 306
Query: 315 WFIAVCYAFVFSALIEFATVNY-FTKRG------WAWDGKSVVNDKKKEKASVMIQNNAY 367
++ C+ FVF AL+E+A VNY F RG A S N+K + + M +
Sbjct: 307 MYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENI 366
Query: 368 AVAVANYAPNLSK--------DPVLSTISKSATTPEPNK--------------------- 398
++ ++ DP + ++ A++ + K
Sbjct: 367 LLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKK 426
Query: 399 -KPENKPAEAKKT---FNSVSKIDRMSRIVFPVLFGTFNLVYWATYLN 442
+ + ++ K T V+ IDR SRI FPV+F FN+VYW Y+N
Sbjct: 427 SRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 276 bits (707), Expect = 2e-74
Identities = 163/444 (36%), Positives = 242/444 (54%), Gaps = 42/444 (9%)
Query: 38 NITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKW 97
N++ +D+LL GYD RLRP G V NI + S VS+ +M+YT+ ++F+Q W
Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92
Query: 98 KDERLKFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLY 156
+D+RL + G P+N L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY
Sbjct: 93 RDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY 151
Query: 157 TMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLN 216
+R+T A C M L +P+D +C L+ SY YTT ++ + W D + L
Sbjct: 152 GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELP 209
Query: 217 QYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNR 276
Q+ ++ + + +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N
Sbjct: 210 QFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINY 269
Query: 277 ESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY 336
++ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 270 DASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNY 329
Query: 337 -FTKRG------WAWDGKSVVNDKKKEKAS-VMIQNNAY--AVAVANYAPNLS---KDPV 383
F RG A ND+ K +++ V N ++ V N +S D
Sbjct: 330 IFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTR 389
Query: 384 LSTIS--------KSATTPE------------PNKKPENKPAEAK-----KTFNSVSKID 418
S IS + + P P+KK + ++ V+ ID
Sbjct: 390 NSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAID 449
Query: 419 RMSRIVFPVLFGTFNLVYWATYLN 442
R SRIVFP F FNLVYW Y+N
Sbjct: 450 RWSRIVFPFTFSLFNLVYWLYYVN 473
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 276 bits (707), Expect = 2e-74
Identities = 163/444 (36%), Positives = 242/444 (54%), Gaps = 42/444 (9%)
Query: 38 NITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKW 97
N++ +D+LL GYD RLRP G V NI + S VS+ +M+YT+ ++F+Q W
Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92
Query: 98 KDERLKFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLY 156
+D+RL + G P+N L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY
Sbjct: 93 RDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY 151
Query: 157 TMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLN 216
+R+T A C M L +P+D +C L+ SY YTT ++ + W D + L
Sbjct: 152 GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELP 209
Query: 217 QYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNR 276
Q+ ++ + + +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N
Sbjct: 210 QFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINY 269
Query: 277 ESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY 336
++ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 270 DASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNY 329
Query: 337 -FTKRG------WAWDGKSVVNDKKKEKAS-VMIQNNAY--AVAVANYAPNLS---KDPV 383
F RG A ND+ K +++ V N ++ V N +S D
Sbjct: 330 IFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTR 389
Query: 384 LSTIS--------KSATTPE------------PNKKPENKPAEAK-----KTFNSVSKID 418
S IS + + P P+KK + ++ V+ ID
Sbjct: 390 NSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAID 449
Query: 419 RMSRIVFPVLFGTFNLVYWATYLN 442
R SRIVFP F FNLVYW Y+N
Sbjct: 450 RWSRIVFPFTFSLFNLVYWLYYVN 473
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 276 bits (706), Expect = 3e-74
Identities = 155/401 (38%), Positives = 240/401 (59%), Gaps = 13/401 (3%)
Query: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
LD+L+ GYD R+RP V NI++ SFG V++T M+Y +++F RQ+W D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107
Query: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
+ P + L L+ M IW PD FF N K + H++T NKLLRI +G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
+ CPM L++FPMD +C ++ S+ YT +++ + W + VQVA +G L Q+ L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVA-EGLTLPQFILK 224
Query: 222 GQS-IGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
+ +G T +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
Query: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
Query: 341 GWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLS-KDPVLSTISKSATTPEPNKK 399
+ + K++ K + + + + + L KD + + P+P
Sbjct: 345 HKEF-LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQP--- 400
Query: 400 PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
P++ A KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 401 PKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 276 bits (706), Expect = 3e-74
Identities = 155/401 (38%), Positives = 240/401 (59%), Gaps = 13/401 (3%)
Query: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
LD+L+ GYD R+RP V NI++ SFG V++T M+Y +++F RQ+W D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107
Query: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
+ P + L L+ M IW PD FF N K + H++T NKLLRI +G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
+ CPM L++FPMD +C ++ S+ YT +++ + W + VQVA +G L Q+ L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVA-EGLTLPQFILK 224
Query: 222 GQS-IGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
+ +G T +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
Query: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
Query: 341 GWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLS-KDPVLSTISKSATTPEPNKK 399
+ + K++ K + + + + + L KD + + P+P
Sbjct: 345 HKEF-LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQP--- 400
Query: 400 PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
P++ A KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 401 PKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 276 bits (705), Expect = 4e-74
Identities = 154/401 (38%), Positives = 240/401 (59%), Gaps = 13/401 (3%)
Query: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
Query: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
+ P + L L+ M IW PD FF N K + H++T NKLLRI +G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
+ CPM L++FPMD +C ++ S+ YT +++ + W + VQVA +G L Q+ L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVA-EGLTLPQFILK 224
Query: 222 GQS-IGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
+ +G T +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
Query: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
Query: 341 GWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLS-KDPVLSTISKSATTPEPNKK 399
+ + K++ K + + + + + L KD + + P+P
Sbjct: 345 HKEF-LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQP--- 400
Query: 400 PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
P++ A KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 401 PKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 275 bits (703), Expect = 6e-74
Identities = 169/459 (36%), Positives = 257/459 (55%), Gaps = 34/459 (7%)
Query: 6 NIYNMQFLLFVFLVWDPARLV--LANIQEDEAKNNITIFTR--ILDRLL---DGYDNRLR 58
++ + + L+ F W+ A L+ +A + D A++ + LD+L+ GYD R+R
Sbjct: 3 HVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIR 62
Query: 59 PGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLM 117
P V NI++ SFG +++T M+Y +++F RQKW D RL + P + L L+ M
Sbjct: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSM 122
Query: 118 ASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDA 177
IW PD FF N K + H +T NKLLRI +G +LY++RLT+ CPM L++FPMD
Sbjct: 123 LDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDV 182
Query: 178 HSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS-STGE 236
+C ++ S+ YT +++ + W A VQVA +G L Q+ L + + K +TG+
Sbjct: 183 QTCIMQLESFGYTMNDLIFEWQDEAP--VQVA-EGLTLPQFLLKEEKDLRYCTKHYNTGK 239
Query: 237 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 296
+T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR G+TTVLTMTT
Sbjct: 240 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 299
Query: 297 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVV--NDKK 354
S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++ K ++ K+
Sbjct: 300 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-----HKELLRFRRKR 354
Query: 355 KEKASVMIQNNAYAVAVANYAPNLSK--------DPVLSTISKSATTPEPNKKP----EN 402
K K Y + + S+ P L +K TP+ P
Sbjct: 355 KNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQ--AKDGMTPKGPNHPVQVMPK 412
Query: 403 KPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
P E +K F + KID +SR FP+ F FN+ YW Y
Sbjct: 413 SPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,316,980
Number of Sequences: 37866
Number of extensions: 602587
Number of successful extensions: 1861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1668
Number of HSP's gapped (non-prelim): 104
length of query: 451
length of database: 18,247,518
effective HSP length: 106
effective length of query: 345
effective length of database: 14,233,722
effective search space: 4910634090
effective search space used: 4910634090
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.