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Search of human proteins with 16418379
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16418379 syntaxin 1B [Homo sapiens]
(288 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16418379 syntaxin 1B [Homo sapiens] 558 e-159
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 472 e-133
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens] 370 e-103
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens] 368 e-102
gi|4759184 syntaxin 3 [Homo sapiens] 327 6e-90
gi|20149560 syntaxin 4 [Homo sapiens] 245 4e-65
gi|33667038 syntaxin 11 [Homo sapiens] 174 6e-44
gi|49258196 syntaxin 19 [Homo sapiens] 149 4e-36
gi|28933465 syntaxin 12 [Homo sapiens] 90 2e-18
gi|170932494 syntaxin 7 [Homo sapiens] 87 1e-17
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 81 9e-16
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 81 9e-16
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 81 9e-16
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 81 9e-16
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 55 7e-08
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 51 1e-06
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 48 1e-05
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 47 1e-05
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 47 1e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 47 1e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 46 4e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 46 4e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 45 7e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 45 7e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 45 7e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 45 7e-05
gi|45505178 cancer antigen 1 [Homo sapiens] 45 1e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 45 1e-04
gi|34577114 cytomatrix protein p110 [Homo sapiens] 45 1e-04
gi|71061468 centromere protein E [Homo sapiens] 44 1e-04
>gi|16418379 syntaxin 1B [Homo sapiens]
Length = 288
Score = 558 bits (1438), Expect = e-159
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI 60
MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI
Sbjct: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI 60
Query: 61 LAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHS 120
LAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHS
Sbjct: 61 LAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHS 120
Query: 121 TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDI 180
TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDI
Sbjct: 121 TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDI 180
Query: 181 KMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSV 240
KMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSV
Sbjct: 181 KMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSV 240
Query: 241 DYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL 288
DYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL
Sbjct: 241 DYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL 288
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 472 bits (1215), Expect = e-133
Identities = 240/285 (84%), Positives = 270/285 (94%), Gaps = 1/285 (0%)
Query: 1 MKDRTQELRSAKDSDDEEEV-VHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSA 59
MKDRTQELR+AKDSDD+++V V VDRD FMDEFFEQVEEIRG I+K++E+VE+VK++HSA
Sbjct: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60
Query: 60 ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQH 119
ILA+PNPDEKTK+ELE+L +DIKKTANKVRSKLK+IEQSIEQEEGLNRSSADLRIRKTQH
Sbjct: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120
Query: 120 STLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDD 179
STLSRKFVEVM+EYNATQS YR+RCK RIQRQLEITGRTTT+EELEDMLESG AIF
Sbjct: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180
Query: 180 IKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHS 239
I MDS ++KQAL+EIETRH+EIIKLE SIRELHDMF+DMAMLVESQGEMIDRIEYNVEH+
Sbjct: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240
Query: 240 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGG 284
VDYVERAVSDTKKAVKYQSKARRKKIMIIICCV+LG+V+AS++GG
Sbjct: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGG 285
>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
Length = 287
Score = 370 bits (951), Expect = e-103
Identities = 186/286 (65%), Positives = 234/286 (81%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI 60
M+DR +L + + +DD + VV V++DHFMD+FF QVEEIR I+K+++ VE+VKK HS I
Sbjct: 1 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
Query: 61 LAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHS 120
L+APNP+ K K+ELEDL +IKKTANK+R+KLKAIEQS +Q+E NR+S DLRIR+TQHS
Sbjct: 61 LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
Query: 121 TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDI 180
LSRKFVE M EYN Q+ +R+R K RIQRQLEITGRTTT++ELE+MLESGK +IFT DI
Sbjct: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
Query: 181 KMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSV 240
DSQ+T+QALNEIE+RH +I+KLETSIRELH+MF+DMAM VE+QGEMI+ IE NV ++
Sbjct: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
Query: 241 DYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTL 286
DYVE A +TKKA+KYQSKARRK + IIIC +VL V+L + TL
Sbjct: 241 DYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286
>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
Length = 288
Score = 368 bits (945), Expect = e-102
Identities = 186/287 (64%), Positives = 235/287 (81%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI 60
M+DR +L + + +DD + VV V++DHFMD+FF QVEEIR I+K+++ VE+VKK HS I
Sbjct: 1 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
Query: 61 LAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHS 120
L+APNP+ K K+ELEDL +IKKTANK+R+KLKAIEQS +Q+E NR+S DLRIR+TQHS
Sbjct: 61 LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
Query: 121 TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDI 180
LSRKFVE M EYN Q+ +R+R K RIQRQLEITGRTTT++ELE+MLESGK +IFT DI
Sbjct: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
Query: 181 KMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSV 240
DSQ+T+QALNEIE+RH +I+KLETSIRELH+MF+DMAM VE+QGEMI+ IE NV ++
Sbjct: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
Query: 241 DYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLG 287
DYVE A +TKKA+KYQSKARRKK +II VVL ++A IG ++G
Sbjct: 241 DYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVG 287
>gi|4759184 syntaxin 3 [Homo sapiens]
Length = 289
Score = 327 bits (839), Expect = 6e-90
Identities = 175/291 (60%), Positives = 230/291 (79%), Gaps = 6/291 (2%)
Query: 1 MKDRTQELRS---AKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQH 57
MKDR ++L++ +D D + + +D FMDEFF ++EE R I+K+SE VE+ KK +
Sbjct: 1 MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
Query: 58 SAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKT 117
S IL+AP P+ KTK +LE LT +IKK AN VR+KLK++E+ IE++E RSSADLRIRK+
Sbjct: 61 SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118
Query: 118 QHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFT 177
QHS LSRKFVEVMT+YN Q +R+R K RIQRQLEITG+ TT+EELE+MLESG AIFT
Sbjct: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
Query: 178 DDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVE 237
I +DSQ++KQAL+EIE RH +I++LE+SI+ELHDMF+D+AMLVE+QGEM+D IE NV
Sbjct: 179 SGI-IDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237
Query: 238 HSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL 288
H+VD+VE+A +TKKAVKYQS+AR+K I+II+ VVL +LA IG ++GL
Sbjct: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGL 288
>gi|20149560 syntaxin 4 [Homo sapiens]
Length = 297
Score = 245 bits (625), Expect = 4e-65
Identities = 140/296 (47%), Positives = 196/296 (66%), Gaps = 11/296 (3%)
Query: 1 MKDRTQELRSAKDSDDEEE------VVHVDRDHFM---DEFFEQVEEIRGCIEKLSEDVE 51
M+DRT ELR DS DEE+ VVH +EFF +V IR I KL V+
Sbjct: 1 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ 60
Query: 52 QVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSAD 111
+++KQ ILA P P+E KQEL++L +IK+ ++R +LKAIE E+ + N +S +
Sbjct: 61 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE-NYNSVN 119
Query: 112 LRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLES 170
R+RKTQH LS++FVE++ + N+ QS+YR++ +RI+RQL+IT ++EELE ML+S
Sbjct: 120 TRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDS 179
Query: 171 GKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMID 230
G+ +F +I D+Q+T+QALNEI RH+EI +LE SIRELHD+F +A VE QGEMI+
Sbjct: 180 GQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMIN 239
Query: 231 RIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTL 286
RIE N+ S DYVER K A++ Q KAR+KK++I IC + V+LA IG T+
Sbjct: 240 RIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTV 295
>gi|33667038 syntaxin 11 [Homo sapiens]
Length = 287
Score = 174 bits (442), Expect = 6e-44
Identities = 98/287 (34%), Positives = 163/287 (56%), Gaps = 14/287 (4%)
Query: 1 MKDRTQEL--------RSAKDSDDEEEVVHVD----RDHFMDEFFEQVEEIRGCIEKLSE 48
MKDR EL + D DDE + H D DH ++ + + +I+ + L
Sbjct: 1 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
Query: 49 DVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 108
DV+++ KQ++ L + K++ + IK + KL+A+++ E E +
Sbjct: 61 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
Query: 109 -SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 167
SA RI + Q++ L+ F M +YN + K RD CK RIQRQLEI G+ + +++EDM
Sbjct: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
Query: 168 LESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGE 227
E GK +F++++ D + + ALNEIE+RH E+++LE+ IR++H++F+ MA+LVE Q +
Sbjct: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
Query: 228 MIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVL 274
++ IE NV+ +VDY +A + +KAV+Y+ K + + CC L
Sbjct: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK-NPCRTLCCFCCPCL 286
>gi|49258196 syntaxin 19 [Homo sapiens]
Length = 294
Score = 149 bits (375), Expect = 4e-36
Identities = 86/283 (30%), Positives = 158/283 (55%), Gaps = 14/283 (4%)
Query: 1 MKDRTQELRSAKDS-----DDEEEVVHV------DRDHFMDEFFEQVEEIRGCIEKLSED 49
+K RT+E+ ++DS + EE+ V + +R+ + ++++++ I L+++
Sbjct: 8 LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
Query: 50 VEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNR-S 108
V++ +Q +++A+ K+E +T +IK A + L + + +++ E N S
Sbjct: 68 VQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENGPS 126
Query: 109 SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDML 168
S RI K+QH+ + R F ++M YN T + +++CK I RQLE+ G+ + E++ DML
Sbjct: 127 SVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDML 186
Query: 169 ESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEM 228
GK +F + + + +TK L+EIE RH E++ LE I++L D+F+ +++LVE QGE
Sbjct: 187 HQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGES 246
Query: 229 IDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICC 271
I+ IE V + +YV AVKY+ K +++ CC
Sbjct: 247 INNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCC 288
>gi|28933465 syntaxin 12 [Homo sapiens]
Length = 276
Score = 90.1 bits (222), Expect = 2e-18
Identities = 65/255 (25%), Positives = 127/255 (49%), Gaps = 17/255 (6%)
Query: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPD--EKTKQELEDLTADIKKTANKV 88
+F ++ G I+++S+ Q+K S + + ++ Q+L+ T + K N++
Sbjct: 21 DFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQLQHSTNQLAKETNEL 80
Query: 89 RSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRI 148
+L ++ L S+++ R ++ Q L F + + A Q + ++ K+ I
Sbjct: 81 LKELGSLP--------LPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESI 132
Query: 149 QRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQ-----MTKQALNEIETRHNEIIK 203
R + + + E+ L S + +M SQ +T+Q L I+ R I +
Sbjct: 133 ARARAGSRLSAEERQREEQLVS--FDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQ 190
Query: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
LE I +++ +F D+AM++ QG++ID IE NVE S +VERA ++A YQ K+R+K
Sbjct: 191 LEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKK 250
Query: 264 KIMIIICCVVLGVVL 278
++++ V+ ++L
Sbjct: 251 MCILVLVLSVIILIL 265
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 87.4 bits (215), Expect = 1e-17
Identities = 58/216 (26%), Positives = 108/216 (50%), Gaps = 4/216 (1%)
Query: 70 TKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEV 129
T Q+ +L +++ K ++ I++ L + ++ R RK Q L +F
Sbjct: 41 TPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTS 100
Query: 130 MTEYNATQSKYRDRCKD---RIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQM 186
+T + Q + +R K+ R++ ++G + E L S + D ++
Sbjct: 101 LTNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSKERNLVSWESQTQPQVQVQDEEI 160
Query: 187 TKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERA 246
T+ L I R + I +LE I +++++F D+ M++ QG++ID IE NVE++ +V++A
Sbjct: 161 TEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQA 220
Query: 247 VSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSI 282
+A YQ K+ RK + III +V+GV + S I
Sbjct: 221 NQQLSRAADYQRKS-RKTLCIIILILVIGVAIISLI 255
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 81.3 bits (199), Expect = 9e-16
Identities = 65/260 (25%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE--LEDLTADIKKTANKV 88
++ + V+EI+ + ++ + ++++ H L P D+ +++E +E T +I + ++
Sbjct: 77 KWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 136
Query: 89 RSKLKAIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
+ ++A+ ++ ++EG R+ ++L++ E+ T + QS Y R K
Sbjct: 137 QRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELSTSFRHAQSGYLKRMK 188
Query: 146 DRIQRQLEITGRTTTNEELEDMLESGKLAI--FTDDIKMDSQMTKQALNEIETRHNEIIK 203
+R +R T+ L D + L FT+D + + +Q +E R EI +
Sbjct: 189 NREERSQHFFD---TSVPLMDDGDDNTLYHRGFTEDQLV---LVEQNTLMVEEREREIRQ 242
Query: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
+ SI +L+++F D+ ++ QG ++DRI+YNVE S E + KA +YQ K RK
Sbjct: 243 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRK 301
Query: 264 KIMIIICCVVLGVVLASSIG 283
++I+I V++ V++ +G
Sbjct: 302 MLVILILFVIIIVLIVVLVG 321
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 81.3 bits (199), Expect = 9e-16
Identities = 65/260 (25%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE--LEDLTADIKKTANKV 88
++ + V+EI+ + ++ + ++++ H L P D+ +++E +E T +I + ++
Sbjct: 60 KWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 119
Query: 89 RSKLKAIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
+ ++A+ ++ ++EG R+ ++L++ E+ T + QS Y R K
Sbjct: 120 QRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELSTSFRHAQSGYLKRMK 171
Query: 146 DRIQRQLEITGRTTTNEELEDMLESGKLAI--FTDDIKMDSQMTKQALNEIETRHNEIIK 203
+R +R T+ L D + L FT+D + + +Q +E R EI +
Sbjct: 172 NREERSQHFFD---TSVPLMDDGDDNTLYHRGFTEDQLV---LVEQNTLMVEEREREIRQ 225
Query: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
+ SI +L+++F D+ ++ QG ++DRI+YNVE S E + KA +YQ K RK
Sbjct: 226 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRK 284
Query: 264 KIMIIICCVVLGVVLASSIG 283
++I+I V++ V++ +G
Sbjct: 285 MLVILILFVIIIVLIVVLVG 304
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 81.3 bits (199), Expect = 9e-16
Identities = 65/260 (25%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE--LEDLTADIKKTANKV 88
++ + V+EI+ + ++ + ++++ H L P D+ +++E +E T +I + ++
Sbjct: 73 KWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 132
Query: 89 RSKLKAIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
+ ++A+ ++ ++EG R+ ++L++ E+ T + QS Y R K
Sbjct: 133 QRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELSTSFRHAQSGYLKRMK 184
Query: 146 DRIQRQLEITGRTTTNEELEDMLESGKLAI--FTDDIKMDSQMTKQALNEIETRHNEIIK 203
+R +R T+ L D + L FT+D + + +Q +E R EI +
Sbjct: 185 NREERSQHFFD---TSVPLMDDGDDNTLYHRGFTEDQLV---LVEQNTLMVEEREREIRQ 238
Query: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
+ SI +L+++F D+ ++ QG ++DRI+YNVE S E + KA +YQ K RK
Sbjct: 239 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRK 297
Query: 264 KIMIIICCVVLGVVLASSIG 283
++I+I V++ V++ +G
Sbjct: 298 MLVILILFVIIIVLIVVLVG 317
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 81.3 bits (199), Expect = 9e-16
Identities = 65/260 (25%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE--LEDLTADIKKTANKV 88
++ + V+EI+ + ++ + ++++ H L P D+ +++E +E T +I + ++
Sbjct: 56 KWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 115
Query: 89 RSKLKAIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
+ ++A+ ++ ++EG R+ ++L++ E+ T + QS Y R K
Sbjct: 116 QRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELSTSFRHAQSGYLKRMK 167
Query: 146 DRIQRQLEITGRTTTNEELEDMLESGKLAI--FTDDIKMDSQMTKQALNEIETRHNEIIK 203
+R +R T+ L D + L FT+D + + +Q +E R EI +
Sbjct: 168 NREERSQHFFD---TSVPLMDDGDDNTLYHRGFTEDQLV---LVEQNTLMVEEREREIRQ 221
Query: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
+ SI +L+++F D+ ++ QG ++DRI+YNVE S E + KA +YQ K RK
Sbjct: 222 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRK 280
Query: 264 KIMIIICCVVLGVVLASSIG 283
++I+I V++ V++ +G
Sbjct: 281 MLVILILFVIIIVLIVVLVG 300
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 55.1 bits (131), Expect = 7e-08
Identities = 64/295 (21%), Positives = 134/295 (45%), Gaps = 43/295 (14%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIR-------GCIE-------KL 46
+K E S ++ +EEE + + + QV +++ GC+E KL
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
Query: 47 SEDVEQVKKQHSAILAAPNPDEKTK----QELEDLTADI---KKTANKVRSKLKAIEQSI 99
+D+E + ++H +AA + EKTK QEL+DL D+ +++A + K K +Q +
Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450
Query: 100 EQE--------EGLNRSSADLRIRKTQHSTLSRKFVEVM---TEYNATQSKYRDRCKDRI 148
+E E +R+ A+ R ++T+ +L+R E M E ++R +D +
Sbjct: 1451 AEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLM 1510
Query: 149 QRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSI 208
+ ++ G++ LE K A+ +M +Q+ ++ +E++ + ++LE ++
Sbjct: 1511 SSKDDV-GKSVHE------LEKSKRALEQQVEEMKTQL-EELEDELQATEDAKLRLEVNL 1562
Query: 209 RELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
+ + F ++ + E + + + V +E + D +K AR+K
Sbjct: 1563 QAMKAQF---ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614
Score = 36.6 bits (83), Expect = 0.026
Identities = 43/177 (24%), Positives = 80/177 (45%), Gaps = 18/177 (10%)
Query: 34 EQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLK 93
E+ +++ + ++ ++E +KQ S +AA +K + +L+DL A I +ANK R
Sbjct: 1582 EKKKQLVRQVREMEAELEDERKQRSMAVAA---RKKLEMDLKDLEAHI-DSANKNR---- 1633
Query: 94 AIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLE 153
+++I+Q L D +R+ + SR+ E++ + + K + + IQ Q E
Sbjct: 1634 --DEAIKQLRKLQAQMKDC-MRELDDTRASRE--EILAQAKENEKKLKSMEAEMIQLQEE 1688
Query: 154 ITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRE 210
+ + + E +LA D+I S AL E I +LE + E
Sbjct: 1689 LAAAERAKRQAQQ--ERDELA---DEIANSSGKGALALEEKRRLEARIAQLEEELEE 1740
Score = 34.7 bits (78), Expect = 0.100
Identities = 49/294 (16%), Positives = 119/294 (40%), Gaps = 45/294 (15%)
Query: 9 RSAKDSDDEEEVVHVDR-DHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPD 67
R + D ++ H+D + DE +Q+ +++ ++ +++ + ILA +
Sbjct: 1612 RKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKEN 1671
Query: 68 EK-------------------------TKQELEDLTADIKKTANK----------VRSKL 92
EK +QE ++L +I ++ K + +++
Sbjct: 1672 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARI 1731
Query: 93 KAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQL 152
+E+ +E+E+G N + R++K + + ++ T+ N +S + R Q +
Sbjct: 1732 AQLEEELEEEQG-NTELINDRLKKA-----NLQIDQINTDLNLERSHAQKNENARQQLER 1785
Query: 153 EITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELH 212
+ +E+E ++S A T +Q+ +Q NE + R ++ + ++L
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Query: 213 DMFV---DMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
D+ + D E + D+ ++ +E A + ++A + K +R+
Sbjct: 1846 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 50.8 bits (120), Expect = 1e-06
Identities = 45/224 (20%), Positives = 102/224 (45%), Gaps = 17/224 (7%)
Query: 72 QELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSAD---LRIRKTQHSTLSRKFVE 128
QEL D ++ NK + A S++Q L RSS L+ + Q L + +
Sbjct: 292 QELRDSLHTAQQETNKT---IAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSD 348
Query: 129 VMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQ--- 185
+ Y Q K ++ + + + + + ++ + K+ +D++ +
Sbjct: 349 AIQCYGVVQKKIAEKSRALLP-MAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQAL 407
Query: 186 ---MTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDY 242
+T++ L I R I+++E+++ +++ + D+A +V QGE +D IE ++E + +
Sbjct: 408 LPDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSH 467
Query: 243 VERAVSDTKKAVKYQSKARRKKIMI----IICCVVLGVVLASSI 282
E A A ++Q + + K + +V+ +++A+S+
Sbjct: 468 AEAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIIIIATSV 511
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/213 (20%), Positives = 95/213 (44%), Gaps = 16/213 (7%)
Query: 45 KLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSI----E 100
++ E+V +K++ + + A E ++EL+ + + N + +L+A ++++ E
Sbjct: 856 EVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEE 915
Query: 101 QEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTT 160
Q E L +S L R + S + E+ +E A K D C + ++++++
Sbjct: 916 QCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFE-LKKEIDDLETMLV 974
Query: 161 NEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAM 220
E E K+ T++++ LNE ++ N K+ ++E H +D
Sbjct: 975 KSEKEKRTTEHKVKNLTEEVEF--------LNEDISKLNRAAKV---VQEAHQQTLDDLH 1023
Query: 221 LVESQGEMIDRIEYNVEHSVDYVERAVSDTKKA 253
+ E + + + +E VD +E A+ +KA
Sbjct: 1024 MEEEKLSSLSKANLKLEQQVDELEGALEQERKA 1056
Score = 42.4 bits (98), Expect = 5e-04
Identities = 43/213 (20%), Positives = 101/213 (47%), Gaps = 26/213 (12%)
Query: 38 EIRGCIEKLSEDVEQVKKQHSAILAAPNPDE----KTKQELEDLTADIKK-------TAN 86
++ +++LSE VE+ ++ +S + A E + K+E++DL + K T +
Sbjct: 926 QLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEH 985
Query: 87 KVRSKLKAIEQSIEQEEGLNRSSA-----------DLRIRKTQHSTLSRKFVEVMTEYNA 135
KV++ + +E E LNR++ DL + + + S+LS+ +++ + +
Sbjct: 986 KVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDE 1045
Query: 136 TQSKYRDRCKDRI--QRQL-EITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALN 192
+ K R+ +R+L ++ G N E + LES + + ++++ Q +
Sbjct: 1046 LEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHL-AEELRKKELELSQMNS 1104
Query: 193 EIETRHNEIIKLETSIRELHDMFVDMAMLVESQ 225
++E + +L+ +++EL D+ +E++
Sbjct: 1105 KVENEKGLVAQLQKTVKELQTQIKDLKEKLEAE 1137
Score = 39.7 bits (91), Expect = 0.003
Identities = 52/257 (20%), Positives = 112/257 (43%), Gaps = 27/257 (10%)
Query: 16 DEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPD--EKTKQE 73
+E+E + F Q+E++RG +EK E Q H+ A + D + +E
Sbjct: 1304 EEKEALINQLSREKSNFTRQIEDLRGQLEK--ETKSQSALAHALQKAQRDCDLLREQYEE 1361
Query: 74 LEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEY 133
+++ A++ +T +KV +++ ++ ++ E + + + DL K + + ++ E M
Sbjct: 1362 EQEVKAELHRTLSKVNAEM--VQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVA 1419
Query: 134 NATQSKYRDRCKDRIQRQLEITGRTTTNEELEDML-ESGKLAIFTDDIKMDSQMTKQALN 192
NA R+ +R + QL++ EL D L + GK+ + + +AL
Sbjct: 1420 NA-----RNASLERARHQLQL--------ELGDALSDLGKVRSAAARLDQKQLQSGKALA 1466
Query: 193 EIETRHNEI-IKLETSIRELHDMFVDMAMLVESQGEMI------DRIEYNVEHSVDYVER 245
+ + +H E L+ S +E+ + ++ L + E I R N++ + +
Sbjct: 1467 DWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTN 1526
Query: 246 AVSDTKKAVKYQSKARR 262
V + K + K ++
Sbjct: 1527 QVREGTKNLTEMEKVKK 1543
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 47.4 bits (111), Expect = 1e-05
Identities = 55/268 (20%), Positives = 121/268 (45%), Gaps = 29/268 (10%)
Query: 12 KDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSED----VEQVKKQHSAILAAPNPD 67
K+ +D +V H+ EF + + + R +E+L ++ + Q+++ H+ I+
Sbjct: 989 KELEDTLQVRHIQ------EFEKVMTDHRVSLEELKKENQQIINQIQESHAEII---QEK 1039
Query: 68 EKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFV 127
EK QEL+ +D+ T K+ +L A++++ E + + + ++T S L ++
Sbjct: 1040 EKQLQELKLKVSDLSDTRCKLEVEL-ALKEAETDEIKILLEESRAQQKETLKSLLEQETE 1098
Query: 128 EVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMT 187
+ TE + K +D ++ E+ RT E + + + +S +
Sbjct: 1099 NLRTEISKLNQKIQDNNENYQVGLAEL--RTLMTIEKDQCISE-----LISRHEEESNIL 1151
Query: 188 KQALNEIETRHNEIIKLETSIRE-----LHDMFVDMAMLVESQGEMIDRIEYNVEHSVDY 242
K LN++ + HN+ ++E +++E + +++ L + E I + E E +
Sbjct: 1152 KAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQN 1211
Query: 243 VERAVSDTKKAVKYQSKARRKKIMIIIC 270
+E+ D +K V Q + R + I + C
Sbjct: 1212 LEK---DRQKLVSSQEQDREQLIQKLNC 1236
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 47.4 bits (111), Expect = 1e-05
Identities = 55/268 (20%), Positives = 121/268 (45%), Gaps = 29/268 (10%)
Query: 12 KDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSED----VEQVKKQHSAILAAPNPD 67
K+ +D +V H+ EF + + + R +E+L ++ + Q+++ H+ I+
Sbjct: 989 KELEDTLQVRHIQ------EFEKVMTDHRVSLEELKKENQQIINQIQESHAEII---QEK 1039
Query: 68 EKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFV 127
EK QEL+ +D+ T K+ +L A++++ E + + + ++T S L ++
Sbjct: 1040 EKQLQELKLKVSDLSDTRCKLEVEL-ALKEAETDEIKILLEESRAQQKETLKSLLEQETE 1098
Query: 128 EVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMT 187
+ TE + K +D ++ E+ RT E + + + +S +
Sbjct: 1099 NLRTEISKLNQKIQDNNENYQVGLAEL--RTLMTIEKDQCISE-----LISRHEEESNIL 1151
Query: 188 KQALNEIETRHNEIIKLETSIRE-----LHDMFVDMAMLVESQGEMIDRIEYNVEHSVDY 242
K LN++ + HN+ ++E +++E + +++ L + E I + E E +
Sbjct: 1152 KAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQN 1211
Query: 243 VERAVSDTKKAVKYQSKARRKKIMIIIC 270
+E+ D +K V Q + R + I + C
Sbjct: 1212 LEK---DRQKLVSSQEQDREQLIQKLNC 1236
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 47.4 bits (111), Expect = 1e-05
Identities = 65/286 (22%), Positives = 122/286 (42%), Gaps = 69/286 (24%)
Query: 6 QELRSAKDSDDEEEVVH--------------VDRDHFMDEFFEQVEEIRGCIEKLSEDVE 51
+E S ++ +EEE D +D+ +E + +KL +D E
Sbjct: 1343 EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAE 1402
Query: 52 QVKKQHSAILAAPNPDEKTK----QELEDLTADI---KKTANKVRSKLKAIEQSIEQEEG 104
+ ++ A + EKTK QEL+DLT D+ ++ A+ + K K +Q + +E+
Sbjct: 1403 ALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKS 1462
Query: 105 L--------NRSSADLRIRKTQHSTLSR---KFVEVMTEYNATQSKYRDRCKD------- 146
+ +R+ A+ R ++T+ +L+R + +E E+ + R +D
Sbjct: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDD 1522
Query: 147 ---------RIQRQLE--ITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQAL---- 191
+ +R LE + T EELED L++ T+D K+ ++ QA+
Sbjct: 1523 VGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA------TEDAKLRLEVNMQAMKAQF 1576
Query: 192 -NEIETRHNE-------IIKLETSIR-ELHDMFVDMAMLVESQGEM 228
+++TR + +IK + EL D A+ V S+ +M
Sbjct: 1577 ERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKM 1622
Score = 37.0 bits (84), Expect = 0.020
Identities = 62/265 (23%), Positives = 109/265 (41%), Gaps = 46/265 (17%)
Query: 29 MDEFFEQVEEIRGCIEK----LSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKT 84
+ E FE + R EK LSE++E +K + L ++ + + E A++KK
Sbjct: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKA 1182
Query: 85 ANKV------------RSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKF---VEV 129
+ + A+E+ EQ E R A+L K T +++ V+V
Sbjct: 1183 LEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKV 1242
Query: 130 MTEYNATQSKYRDRCK-------------DRIQRQLEITGRTTTNE--ELEDMLESGK-- 172
+ + A R + DR++ +L NE + +LE +
Sbjct: 1243 LQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKK 1302
Query: 173 -LAIFTDDIKMDSQM--TKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMI 229
+ D ++SQ+ T++ L E ETR + L + IR+L + + L E Q E
Sbjct: 1303 GIKFAKDAASLESQLQDTQELLQE-ETRQK--LNLSSRIRQLEE---EKNSLQEQQEEE- 1355
Query: 230 DRIEYNVEHSVDYVERAVSDTKKAV 254
+ N+E V ++ ++DTKK V
Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKV 1380
Score = 34.3 bits (77), Expect = 0.13
Identities = 47/232 (20%), Positives = 97/232 (41%), Gaps = 20/232 (8%)
Query: 6 QELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPN 65
+E A+ E+E + ++E E EE ++L D+E + + +
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 66 PDEKTKQELEDLTADIKKTANKVRSKLKAIEQS-IEQEEGLNRSSA----DLRIRKTQHS 120
EK+K+ LE +++ ++ +L+A E + + E + A DL+ R Q+
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNE 1588
Query: 121 TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM---LESGKLA--- 174
R ++ + E A +R QR L + + +L+D+ +E+ A
Sbjct: 1589 EKKRLLIKQVRELEAELE------DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDE 1642
Query: 175 IFTDDIKMDSQMT--KQALNEIETRHNEII-KLETSIRELHDMFVDMAMLVE 223
+ K+ +QM ++ L E +EI + + S ++L + ++ L E
Sbjct: 1643 VIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Score = 33.5 bits (75), Expect = 0.22
Identities = 66/301 (21%), Positives = 123/301 (40%), Gaps = 67/301 (22%)
Query: 11 AKDSDDEEEVVHVDRDH--FMDEFFEQVEEIRGCIEKLSEDVEQVK-------KQH---S 58
AK EEE++ ++ + F+ E + I C +L+E+ E+ K KQ S
Sbjct: 978 AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
Query: 59 AILAAPNPDEKTKQELE--------------DLTADIKKTANKVRSKLKAIEQSIE---- 100
+ +EKT+QELE D A+++ ++++ +L E+ ++
Sbjct: 1038 DLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALA 1097
Query: 101 --QEEGLNRSSADLRIR--KTQHSTLSRKFVEVMTEYNATQSKYRDRCK--DRIQRQLEI 154
+E L++++A +R + Q + L F N + + RD + + ++ +LE
Sbjct: 1098 RGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157
Query: 155 TGRTT-TNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHD 213
T TT +EL E + K+AL E H E I+++
Sbjct: 1158 TLDTTAAQQELRTKRE------------QEVAELKKALEEETKNH------EAQIQDMRQ 1199
Query: 214 MFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTK---------KAVKYQSKARRKK 264
+ Q E R + N+E + +E +D K + VK +S+ +RKK
Sbjct: 1200 RHATALEELSEQLEQAKRFKANLEKNKQGLE---TDNKELACEVKVLQQVKAESEHKRKK 1256
Query: 265 I 265
+
Sbjct: 1257 L 1257
Score = 31.2 bits (69), Expect = 1.1
Identities = 38/203 (18%), Positives = 84/203 (41%), Gaps = 24/203 (11%)
Query: 34 EQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLK 93
E++ +++ K+ ++E+++++H +L N + Q +L A+ A ++R++L
Sbjct: 859 EELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE----AEEMRARLA 914
Query: 94 AIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQ---R 150
A +Q +E+ H SR VE E N + + + IQ
Sbjct: 915 AKKQELEE---------------ILHDLESR--VEEEEERNQILQNEKKKMQAHIQDLEE 957
Query: 151 QLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRE 210
QL+ +LE + K+ ++I + + + E + + I + + + E
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 211 LHDMFVDMAMLVESQGEMIDRIE 233
+ ++A + Q MI +E
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLE 1040
Score = 29.6 bits (65), Expect = 3.2
Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 29 MDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKV 88
+ E F QVE+ R ++ E +E+ + + K++LE+ + + AN
Sbjct: 1851 LKEIFMQVEDERRHADQYKEQMEKANARMKQL----------KRQLEEAEEEATR-ANAS 1899
Query: 89 RSKL-KAIEQSIEQEEGLNRSSADLRIRKTQHSTLS 123
R KL + ++ + E EGL+R + L+ R + +S
Sbjct: 1900 RRKLQRELDDATEANEGLSREVSTLKNRLRRGGPIS 1935
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 45.8 bits (107), Expect = 4e-05
Identities = 64/304 (21%), Positives = 122/304 (40%), Gaps = 47/304 (15%)
Query: 1 MKDRTQELRSAKDSDDEE-EVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSA 59
++D EL+ KD DD E + V+++ E +V+ + + L E + ++ ++ A
Sbjct: 944 LEDECSELK--KDIDDLELTLAKVEKEKHATE--NKVKNLTEELSGLDETIAKLTREKKA 999
Query: 60 ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGL--------NRSSAD 111
+ A Q ED + KT +K+ +++ +E S+EQE+ L + D
Sbjct: 1000 LQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGD 1059
Query: 112 LRIR-------KTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEEL 164
L++ + L + + EY QSK D +Q Q +I EEL
Sbjct: 1060 LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 1119
Query: 165 EDMLESGK----------------LAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSI 208
E+ +E+ + L ++ ++ +T + + R E +KL +
Sbjct: 1120 EEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDL 1179
Query: 209 REL---HDMFV-----DMAMLVESQGEMID---RIEYNVEHSVDYVERAVSDTKKAVKYQ 257
E H+ V A V GE ID R++ +E + + D +++
Sbjct: 1180 EEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESV 1239
Query: 258 SKAR 261
SK++
Sbjct: 1240 SKSK 1243
Score = 43.5 bits (101), Expect = 2e-04
Identities = 54/254 (21%), Positives = 111/254 (43%), Gaps = 27/254 (10%)
Query: 25 RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQEL----EDLTAD 80
R + + ++ EE+ +KL++ ++ ++Q A+ A EKTKQ L EDL D
Sbjct: 1373 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 1432
Query: 81 IKKTANKVRSKLKAIEQSI-----EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNA 135
+++ AN + + L +++ E + S A+L + +LS + ++ Y
Sbjct: 1433 VER-ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEE 1491
Query: 136 TQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGK----LAIFTDDIKMDSQMTKQAL 191
+ ++ + EI T E + E+GK L I+++ + AL
Sbjct: 1492 ALDQLETVKRENKNLEQEIADLT------EQIAENGKTIHELEKSRKQIELEKADIQLAL 1545
Query: 192 NEIET--RHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERA--- 246
E E H E L + EL + ++ + + E I++++ N + +V+ ++ A
Sbjct: 1546 EEAEAALEHEEAKILRIQL-ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDA 1604
Query: 247 -VSDTKKAVKYQSK 259
V +A++ + K
Sbjct: 1605 EVRSRNEAIRLKKK 1618
Score = 32.3 bits (72), Expect = 0.50
Identities = 25/126 (19%), Positives = 65/126 (51%), Gaps = 10/126 (7%)
Query: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRS 90
E EQ++ ++ +KL ++ + K + + ++ K+K LE + ++ ++ R
Sbjct: 1203 ELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARG 1262
Query: 91 KLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVE---VMTEYNATQSKYRDRCKDR 147
K + I++S+ + L + L +T+ LSR+ E ++++ + ++ + + ++
Sbjct: 1263 KNEEIQRSLSE---LTTQKSRL---QTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE- 1315
Query: 148 IQRQLE 153
++RQLE
Sbjct: 1316 LKRQLE 1321
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 45.8 bits (107), Expect = 4e-05
Identities = 53/265 (20%), Positives = 128/265 (48%), Gaps = 42/265 (15%)
Query: 34 EQVEEIRGCIEKLSEDVEQVKKQ------------HSAILAAPNPDE---KTKQELEDLT 78
E++ ++R I++++ E++++Q A+ A +E K K E+++
Sbjct: 382 EEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQI 441
Query: 79 ADIKKTANKVRSKLKAIEQSIEQE--EGLNRSSAD--LRIRKTQHSTLSRKFVEVMTEYN 134
I+KT+ + R L+ ++QE + + +SS + +++K L+RK E+ +
Sbjct: 442 KTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQ 501
Query: 135 ATQSKYRDRCKDRIQRQ----LEITGRTTTNEELE-DMLESGKLAIFTD------DIKMD 183
+ +++++ K +++ L+I+ E L + LE K AI T+ D++ +
Sbjct: 502 TREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQE 561
Query: 184 SQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYV 243
++ + + E+E+ LE S++E + D+A+ +E+ ++ ++N E +V V
Sbjct: 562 AETYRTRILELES------SLEKSLQENKNQSKDLAVHLEA-----EKNKHNKEITV-MV 609
Query: 244 ERAVSDTKKAVKYQSKARRKKIMII 268
E+ ++ + Q +K+ ++
Sbjct: 610 EKHKTELESLKHQQDALWTEKLQVL 634
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/296 (20%), Positives = 126/296 (42%), Gaps = 36/296 (12%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCI---------EKLSEDVE 51
+ +R QEL KD E+ + + EQ+E+ +G + E L E
Sbjct: 323 LDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEE 382
Query: 52 QVKKQHSAILAAPNPDEKTK-----------QELEDLTADIKKTANKVRSKLKAIEQSIE 100
++ + S I E+ + +ELE + +KT + R KLKA + E
Sbjct: 383 EIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EEARRKLKA--EMDE 439
Query: 101 QEEGLNRSSADLRIRKTQH-STLSRKFVEVMTEYNATQSKYRDRC--KDRIQRQLEITGR 157
Q + + ++S + RI Q S + ++ V+VM + + Q + K+ +++ E+T +
Sbjct: 440 QIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKK 499
Query: 158 TTTNE-ELEDMLESGKLAIFTDDIKMDSQMTKQ---ALNEIETRHNEIIKLETSIRELHD 213
T E E ++ ++ ++ +K+ + +Q AL E+E + I + E +
Sbjct: 500 LQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAI------LTESEN 553
Query: 214 MFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIII 269
D+ E+ I +E ++E S+ + D ++ + K+I +++
Sbjct: 554 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMV 609
Score = 38.5 bits (88), Expect = 0.007
Identities = 43/236 (18%), Positives = 95/236 (40%), Gaps = 28/236 (11%)
Query: 17 EEEVVHVDRDHFMDEF-----FEQVEEIRGCIEKLSEDVEQVKKQHSA------------ 59
++EV V+ + ++ +Q++ E L E+ E+ K H
Sbjct: 1866 QKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQH 1925
Query: 60 ------ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQE--EGLNRSSAD 111
+ A +K +E+ L D++ + + +L+ +++ +QE E + + D
Sbjct: 1926 NDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQED 1985
Query: 112 LRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESG 171
L ++ +STL + E T+ + + K+ I + E+ + + E
Sbjct: 1986 LELK--HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLK 2043
Query: 172 KLAIFTDDIKMDSQMTKQALNEIETRHNEIIK-LETSIRELHDMFVDMAMLVESQG 226
K+A DD+K ++ ++ L+ E ++ L+T + EL + E+ G
Sbjct: 2044 KIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPG 2099
Score = 37.4 bits (85), Expect = 0.015
Identities = 42/180 (23%), Positives = 77/180 (42%), Gaps = 37/180 (20%)
Query: 38 EIRGCIEKLSEDVEQVKKQHSAILAAPNPDE------KTKQELEDLTADIKKTANKVRSK 91
E + I L E++E+ K++S I+A E + KQ LE++ D++KT +
Sbjct: 1789 EDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT 1848
Query: 92 LKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQ 151
+ +EQ I++ + S L R+ E SKY +++Q
Sbjct: 1849 CQILEQKIKELD----------------SCLVRQKEVHRVEMEELTSKY-----EKLQAL 1887
Query: 152 LEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEI-IKLETSIRE 210
++ GR E LE+ T++ + + L+ +E +HN++ KL + RE
Sbjct: 1888 QQMDGRNKPTELLEEN---------TEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAERE 1938
Score = 33.1 bits (74), Expect = 0.29
Identities = 56/249 (22%), Positives = 113/249 (45%), Gaps = 32/249 (12%)
Query: 34 EQVEEIRGCIE----KLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVR 89
EQ+ E++ E K+SE ++K + + EK+ + LED + + KK + ++
Sbjct: 1155 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELA 1214
Query: 90 SKL----KAIEQSIEQE--EGLNRSSADL-----RIRKTQHSTLSRKFVEVMTEYNATQS 138
+L K E +E + E +N SS+ RI QH T K ++ ++
Sbjct: 1215 IQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSEL 1274
Query: 139 KYRDRCKDRIQRQLEITGRTTTN--EELEDMLESGK-----LAIFTDDIKMDSQMTKQAL 191
+ + R Q L I+ + T+ EE E+ ++S K L + ++ + +QA
Sbjct: 1275 EAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAA 1334
Query: 192 NEIETRHNEIIK-LETSI-------RELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYV 243
+E E+ ++ K L +I EL + V+++ L + ++ +++ ++ S+
Sbjct: 1335 SEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSI--SLSEK 1392
Query: 244 ERAVSDTKK 252
E A+S +K
Sbjct: 1393 EAAISSLRK 1401
Score = 31.6 bits (70), Expect = 0.84
Identities = 38/171 (22%), Positives = 71/171 (41%), Gaps = 17/171 (9%)
Query: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRS 90
E E V++++ E E +VK+ IL N K ELE +++ V+S
Sbjct: 1558 EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1617
Query: 91 K---LKAIEQSIEQEEGLN----RSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDR 143
K LKA+E +E E + A+ +I + LS + E +Y +
Sbjct: 1618 KEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLS-QMEEKEEQYKKGTESHLSE 1676
Query: 144 CKDRIQRQ------LEITGRTTTNEELEDML---ESGKLAIFTDDIKMDSQ 185
++Q + LE ++ + + E ++ + +A +T+ + DSQ
Sbjct: 1677 LNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQ 1727
Score = 30.4 bits (67), Expect = 1.9
Identities = 28/154 (18%), Positives = 75/154 (48%), Gaps = 20/154 (12%)
Query: 1 MKDRTQELR-SAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSA 59
+ + QEL + K++ ++ + V + ++ E+ ++ I + +D+++ K++
Sbjct: 2005 LAQKEQELEMTIKETINKAQEVEAE---LLESHQEETNQLLKKIAEKDDDLKRTAKRYEE 2061
Query: 60 ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQH 119
IL A E++TA ++ ++ K +Q +EQEE + + +TQ
Sbjct: 2062 ILDARE---------EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQ- 2111
Query: 120 STLSRKFVEVMTEYNATQSKYRDR---CKDRIQR 150
L++K ++++ + ++R++ +DR+++
Sbjct: 2112 --LAQK-TTLISDSKLKEQEFREQIHNLEDRLKK 2142
Score = 30.0 bits (66), Expect = 2.5
Identities = 50/293 (17%), Positives = 119/293 (40%), Gaps = 32/293 (10%)
Query: 9 RSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPN-PD 67
++ KD ++ E++ +RD + E VE + I++ +++Q + + +
Sbjct: 752 KALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATH 811
Query: 68 EKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFV 127
E+TK E L +K + ++ +Q E E +L K Q L ++
Sbjct: 812 EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLE 871
Query: 128 EVMTEY--------NATQSKYRDRCKDRIQ--------------------RQLEI-TGRT 158
+ +E +SK D K++ Q +++EI T +
Sbjct: 872 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKL 931
Query: 159 TTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSI-RELHDMFVD 217
+ E+ +L F + K ++ ++A ET +++ E + +EL + ++
Sbjct: 932 SAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALE 991
Query: 218 MAMLVES-QGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIII 269
++ + +M++ + N D V R ++ K+ ++ ++ R+++ +I
Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVI 1044
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 45.1 bits (105), Expect = 7e-05
Identities = 72/301 (23%), Positives = 128/301 (42%), Gaps = 49/301 (16%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIR-------GCIEKLSEDVEQV 53
+K + + A+D +EE+ + R + E+ ++E+ R +KL D++ +
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Query: 54 KKQHSAILAAPNPDEKTKQ-------------ELEDLTA---DIKKTANKVRSKLKAIEQ 97
+ Q + A +E KQ ELED A +I TA + K K++E
Sbjct: 1630 ELQADS--AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1687
Query: 98 SIEQ-EEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITG 156
+ Q +E L + + + L+ + ++ NA Q + R R + RI QLE
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR-RLEARIA-QLE--- 1742
Query: 157 RTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIK-------LETSIR 209
EELE+ E G + +D ++ +Q +Q NE+ T + K LE +
Sbjct: 1743 -----EELEE--EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 210 ELHDMFVDMAMLVESQ-GEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII 268
EL +M V+S+ I +E + + VE+ + + A K K + KK+ I
Sbjct: 1796 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEI 1854
Query: 269 I 269
+
Sbjct: 1855 L 1855
Score = 36.6 bits (83), Expect = 0.026
Identities = 54/273 (19%), Positives = 111/273 (40%), Gaps = 29/273 (10%)
Query: 4 RTQELRSAKDSDDEE------EVVHVDRDHF--MDEFFEQVEEIRGCIEKLSEDVEQVKK 55
R QE+ K + DEE +V + + H ++E EQ+E+ + L ++ + ++K
Sbjct: 1172 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1231
Query: 56 QHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIR 115
+++ + + KQE+E ++ +++SK E++ R+ + ++
Sbjct: 1232 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA--------RAELNDKVH 1283
Query: 116 KTQHSTLSRKFVEVMTEYNATQSKYRDRCKD--RIQRQLEITGRTTTNEELEDMLESGKL 173
K Q+ S V N + K KD + QL+ T E + + S KL
Sbjct: 1284 KLQNEVES-----VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 174 AIFTDDIKMDSQMTKQALNEIETRHN---EIIKLETSIRELHDMFVDMAMLVESQGEMID 230
++ + + Q E+E + N I L + + D A VE+ E
Sbjct: 1339 RQLEEE---RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1395
Query: 231 RIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
R + +E+ E + K K +++ +++
Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1428
Score = 36.2 bits (82), Expect = 0.034
Identities = 35/202 (17%), Positives = 82/202 (40%), Gaps = 19/202 (9%)
Query: 52 QVKKQHSAILAAPNPDEKTK---QELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 108
QV +Q + A + +KTK Q+ E+ ++++ +++ + +++ ++ E L
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 109 SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDR-------------IQRQLEIT 155
+ ++R+R + ++ E++ E A + DR + ++ QLE
Sbjct: 906 AEEMRVRL---AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 156 GRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMF 215
+LE + K+ D+I + + E + I L T++ E +
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 216 VDMAMLVESQGEMIDRIEYNVE 237
++ L MI +E ++
Sbjct: 1023 KNLTKLKNKHESMISELEVRLK 1044
Score = 35.0 bits (79), Expect = 0.076
Identities = 45/237 (18%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 44 EKLSEDVEQVKKQHSAILAAPN----PDEKTKQELEDLTADIKKTANKVRSKLKAIEQSI 99
E+ ++++ ++K +H ++++ +EK++QELE L ++ A+ ++ ++ I
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 100 --------EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDR--CKDRIQ 149
++EE L + A L Q + +K E+ + Q +++ +
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138
Query: 150 RQLEITGR--TTTNEELEDMLES-GKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLET 206
+Q G ELED L+S + + + K+AL+E ETR + E
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH-----EA 1192
Query: 207 SIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
++E+ + Q E R + N++ + +E+ +D ++ +A+++
Sbjct: 1193 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Score = 32.7 bits (73), Expect = 0.38
Identities = 31/156 (19%), Positives = 66/156 (42%), Gaps = 11/156 (7%)
Query: 17 EEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELED 76
E+E + ++E E EE+ + L ++E + + + EK+K+ LE
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 77 LTADIKKTANKVRSKLKAIEQS-----IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMT 131
++K ++ +L+A E + + + + DL+ R Q+ R+ +
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 132 EYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 167
EY +++ D +R QR L + +L+D+
Sbjct: 1600 EY---ETELED---ERKQRALAAAAKKKLEGDLKDL 1629
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 45.1 bits (105), Expect = 7e-05
Identities = 72/301 (23%), Positives = 128/301 (42%), Gaps = 49/301 (16%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIR-------GCIEKLSEDVEQV 53
+K + + A+D +EE+ + R + E+ ++E+ R +KL D++ +
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL 1636
Query: 54 KKQHSAILAAPNPDEKTKQ-------------ELEDLTA---DIKKTANKVRSKLKAIEQ 97
+ Q + A +E KQ ELED A +I TA + K K++E
Sbjct: 1637 ELQADS--AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1694
Query: 98 SIEQ-EEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITG 156
+ Q +E L + + + L+ + ++ NA Q + R R + RI QLE
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR-RLEARIA-QLE--- 1749
Query: 157 RTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIK-------LETSIR 209
EELE+ E G + +D ++ +Q +Q NE+ T + K LE +
Sbjct: 1750 -----EELEE--EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1802
Query: 210 ELHDMFVDMAMLVESQ-GEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII 268
EL +M V+S+ I +E + + VE+ + + A K K + KK+ I
Sbjct: 1803 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEI 1861
Query: 269 I 269
+
Sbjct: 1862 L 1862
Score = 36.6 bits (83), Expect = 0.026
Identities = 54/273 (19%), Positives = 111/273 (40%), Gaps = 29/273 (10%)
Query: 4 RTQELRSAKDSDDEE------EVVHVDRDHF--MDEFFEQVEEIRGCIEKLSEDVEQVKK 55
R QE+ K + DEE +V + + H ++E EQ+E+ + L ++ + ++K
Sbjct: 1179 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1238
Query: 56 QHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIR 115
+++ + + KQE+E ++ +++SK E++ R+ + ++
Sbjct: 1239 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA--------RAELNDKVH 1290
Query: 116 KTQHSTLSRKFVEVMTEYNATQSKYRDRCKD--RIQRQLEITGRTTTNEELEDMLESGKL 173
K Q+ S V N + K KD + QL+ T E + + S KL
Sbjct: 1291 KLQNEVES-----VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 174 AIFTDDIKMDSQMTKQALNEIETRHN---EIIKLETSIRELHDMFVDMAMLVESQGEMID 230
++ + + Q E+E + N I L + + D A VE+ E
Sbjct: 1346 RQLEEE---RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1402
Query: 231 RIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
R + +E+ E + K K +++ +++
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1435
Score = 36.2 bits (82), Expect = 0.034
Identities = 35/202 (17%), Positives = 82/202 (40%), Gaps = 19/202 (9%)
Query: 52 QVKKQHSAILAAPNPDEKTK---QELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 108
QV +Q + A + +KTK Q+ E+ ++++ +++ + +++ ++ E L
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 109 SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDR-------------IQRQLEIT 155
+ ++R+R + ++ E++ E A + DR + ++ QLE
Sbjct: 913 AEEMRVRL---AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969
Query: 156 GRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMF 215
+LE + K+ D+I + + E + I L T++ E +
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1029
Query: 216 VDMAMLVESQGEMIDRIEYNVE 237
++ L MI +E ++
Sbjct: 1030 KNLTKLKNKHESMISELEVRLK 1051
Score = 35.0 bits (79), Expect = 0.076
Identities = 45/237 (18%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 44 EKLSEDVEQVKKQHSAILAAPN----PDEKTKQELEDLTADIKKTANKVRSKLKAIEQSI 99
E+ ++++ ++K +H ++++ +EK++QELE L ++ A+ ++ ++ I
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 100 --------EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDR--CKDRIQ 149
++EE L + A L Q + +K E+ + Q +++ +
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145
Query: 150 RQLEITGR--TTTNEELEDMLES-GKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLET 206
+Q G ELED L+S + + + K+AL+E ETR + E
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH-----EA 1199
Query: 207 SIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
++E+ + Q E R + N++ + +E+ +D ++ +A+++
Sbjct: 1200 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Score = 32.7 bits (73), Expect = 0.38
Identities = 31/156 (19%), Positives = 66/156 (42%), Gaps = 11/156 (7%)
Query: 17 EEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELED 76
E+E + ++E E EE+ + L ++E + + + EK+K+ LE
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 77 LTADIKKTANKVRSKLKAIEQS-----IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMT 131
++K ++ +L+A E + + + + DL+ R Q+ R+ +
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 132 EYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 167
EY +++ D +R QR L + +L+D+
Sbjct: 1607 EY---ETELED---ERKQRALAAAAKKKLEGDLKDL 1636
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 45.1 bits (105), Expect = 7e-05
Identities = 72/301 (23%), Positives = 128/301 (42%), Gaps = 49/301 (16%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIR-------GCIEKLSEDVEQV 53
+K + + A+D +EE+ + R + E+ ++E+ R +KL D++ +
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL 1636
Query: 54 KKQHSAILAAPNPDEKTKQ-------------ELEDLTA---DIKKTANKVRSKLKAIEQ 97
+ Q + A +E KQ ELED A +I TA + K K++E
Sbjct: 1637 ELQADS--AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1694
Query: 98 SIEQ-EEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITG 156
+ Q +E L + + + L+ + ++ NA Q + R R + RI QLE
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR-RLEARIA-QLE--- 1749
Query: 157 RTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIK-------LETSIR 209
EELE+ E G + +D ++ +Q +Q NE+ T + K LE +
Sbjct: 1750 -----EELEE--EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1802
Query: 210 ELHDMFVDMAMLVESQ-GEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII 268
EL +M V+S+ I +E + + VE+ + + A K K + KK+ I
Sbjct: 1803 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEI 1861
Query: 269 I 269
+
Sbjct: 1862 L 1862
Score = 36.6 bits (83), Expect = 0.026
Identities = 54/273 (19%), Positives = 111/273 (40%), Gaps = 29/273 (10%)
Query: 4 RTQELRSAKDSDDEE------EVVHVDRDHF--MDEFFEQVEEIRGCIEKLSEDVEQVKK 55
R QE+ K + DEE +V + + H ++E EQ+E+ + L ++ + ++K
Sbjct: 1179 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1238
Query: 56 QHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIR 115
+++ + + KQE+E ++ +++SK E++ R+ + ++
Sbjct: 1239 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA--------RAELNDKVH 1290
Query: 116 KTQHSTLSRKFVEVMTEYNATQSKYRDRCKD--RIQRQLEITGRTTTNEELEDMLESGKL 173
K Q+ S V N + K KD + QL+ T E + + S KL
Sbjct: 1291 KLQNEVES-----VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 174 AIFTDDIKMDSQMTKQALNEIETRHN---EIIKLETSIRELHDMFVDMAMLVESQGEMID 230
++ + + Q E+E + N I L + + D A VE+ E
Sbjct: 1346 RQLEEE---RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1402
Query: 231 RIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
R + +E+ E + K K +++ +++
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1435
Score = 36.2 bits (82), Expect = 0.034
Identities = 35/202 (17%), Positives = 82/202 (40%), Gaps = 19/202 (9%)
Query: 52 QVKKQHSAILAAPNPDEKTK---QELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 108
QV +Q + A + +KTK Q+ E+ ++++ +++ + +++ ++ E L
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 109 SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDR-------------IQRQLEIT 155
+ ++R+R + ++ E++ E A + DR + ++ QLE
Sbjct: 913 AEEMRVRL---AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969
Query: 156 GRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMF 215
+LE + K+ D+I + + E + I L T++ E +
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1029
Query: 216 VDMAMLVESQGEMIDRIEYNVE 237
++ L MI +E ++
Sbjct: 1030 KNLTKLKNKHESMISELEVRLK 1051
Score = 35.0 bits (79), Expect = 0.076
Identities = 45/237 (18%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 44 EKLSEDVEQVKKQHSAILAAPN----PDEKTKQELEDLTADIKKTANKVRSKLKAIEQSI 99
E+ ++++ ++K +H ++++ +EK++QELE L ++ A+ ++ ++ I
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 100 --------EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDR--CKDRIQ 149
++EE L + A L Q + +K E+ + Q +++ +
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145
Query: 150 RQLEITGR--TTTNEELEDMLES-GKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLET 206
+Q G ELED L+S + + + K+AL+E ETR + E
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH-----EA 1199
Query: 207 SIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
++E+ + Q E R + N++ + +E+ +D ++ +A+++
Sbjct: 1200 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Score = 32.7 bits (73), Expect = 0.38
Identities = 31/156 (19%), Positives = 66/156 (42%), Gaps = 11/156 (7%)
Query: 17 EEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELED 76
E+E + ++E E EE+ + L ++E + + + EK+K+ LE
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 77 LTADIKKTANKVRSKLKAIEQS-----IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMT 131
++K ++ +L+A E + + + + DL+ R Q+ R+ +
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 132 EYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 167
EY +++ D +R QR L + +L+D+
Sbjct: 1607 EY---ETELED---ERKQRALAAAAKKKLEGDLKDL 1636
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 45.1 bits (105), Expect = 7e-05
Identities = 72/301 (23%), Positives = 128/301 (42%), Gaps = 49/301 (16%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIR-------GCIEKLSEDVEQV 53
+K + + A+D +EE+ + R + E+ ++E+ R +KL D++ +
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Query: 54 KKQHSAILAAPNPDEKTKQ-------------ELEDLTA---DIKKTANKVRSKLKAIEQ 97
+ Q + A +E KQ ELED A +I TA + K K++E
Sbjct: 1630 ELQADS--AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1687
Query: 98 SIEQ-EEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITG 156
+ Q +E L + + + L+ + ++ NA Q + R R + RI QLE
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR-RLEARIA-QLE--- 1742
Query: 157 RTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIK-------LETSIR 209
EELE+ E G + +D ++ +Q +Q NE+ T + K LE +
Sbjct: 1743 -----EELEE--EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 210 ELHDMFVDMAMLVESQ-GEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII 268
EL +M V+S+ I +E + + VE+ + + A K K + KK+ I
Sbjct: 1796 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEI 1854
Query: 269 I 269
+
Sbjct: 1855 L 1855
Score = 36.6 bits (83), Expect = 0.026
Identities = 54/273 (19%), Positives = 111/273 (40%), Gaps = 29/273 (10%)
Query: 4 RTQELRSAKDSDDEE------EVVHVDRDHF--MDEFFEQVEEIRGCIEKLSEDVEQVKK 55
R QE+ K + DEE +V + + H ++E EQ+E+ + L ++ + ++K
Sbjct: 1172 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1231
Query: 56 QHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIR 115
+++ + + KQE+E ++ +++SK E++ R+ + ++
Sbjct: 1232 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA--------RAELNDKVH 1283
Query: 116 KTQHSTLSRKFVEVMTEYNATQSKYRDRCKD--RIQRQLEITGRTTTNEELEDMLESGKL 173
K Q+ S V N + K KD + QL+ T E + + S KL
Sbjct: 1284 KLQNEVES-----VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 174 AIFTDDIKMDSQMTKQALNEIETRHN---EIIKLETSIRELHDMFVDMAMLVESQGEMID 230
++ + + Q E+E + N I L + + D A VE+ E
Sbjct: 1339 RQLEEE---RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1395
Query: 231 RIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
R + +E+ E + K K +++ +++
Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1428
Score = 36.2 bits (82), Expect = 0.034
Identities = 35/202 (17%), Positives = 82/202 (40%), Gaps = 19/202 (9%)
Query: 52 QVKKQHSAILAAPNPDEKTK---QELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 108
QV +Q + A + +KTK Q+ E+ ++++ +++ + +++ ++ E L
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 109 SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDR-------------IQRQLEIT 155
+ ++R+R + ++ E++ E A + DR + ++ QLE
Sbjct: 906 AEEMRVRL---AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 156 GRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMF 215
+LE + K+ D+I + + E + I L T++ E +
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 216 VDMAMLVESQGEMIDRIEYNVE 237
++ L MI +E ++
Sbjct: 1023 KNLTKLKNKHESMISELEVRLK 1044
Score = 35.0 bits (79), Expect = 0.076
Identities = 45/237 (18%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 44 EKLSEDVEQVKKQHSAILAAPN----PDEKTKQELEDLTADIKKTANKVRSKLKAIEQSI 99
E+ ++++ ++K +H ++++ +EK++QELE L ++ A+ ++ ++ I
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 100 --------EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDR--CKDRIQ 149
++EE L + A L Q + +K E+ + Q +++ +
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138
Query: 150 RQLEITGR--TTTNEELEDMLES-GKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLET 206
+Q G ELED L+S + + + K+AL+E ETR + E
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH-----EA 1192
Query: 207 SIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
++E+ + Q E R + N++ + +E+ +D ++ +A+++
Sbjct: 1193 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Score = 32.7 bits (73), Expect = 0.38
Identities = 31/156 (19%), Positives = 66/156 (42%), Gaps = 11/156 (7%)
Query: 17 EEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELED 76
E+E + ++E E EE+ + L ++E + + + EK+K+ LE
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 77 LTADIKKTANKVRSKLKAIEQS-----IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMT 131
++K ++ +L+A E + + + + DL+ R Q+ R+ +
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 132 EYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 167
EY +++ D +R QR L + +L+D+
Sbjct: 1600 EY---ETELED---ERKQRALAAAAKKKLEGDLKDL 1629
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/182 (21%), Positives = 82/182 (45%), Gaps = 23/182 (12%)
Query: 43 IEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQE 102
I KL E+VE++ + I+ N +KT Q LE++ A+ +K + R+ + ++ ++
Sbjct: 218 INKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKK- 276
Query: 103 EGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNE 162
K + L +++ M + N + S+Y + K +++ E+ +
Sbjct: 277 ------------IKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKK 324
Query: 163 ELE-------DMLESGKLAIFTDDIKMDSQ---MTKQALNEIETRHNEIIKLETSIRELH 212
ELE D+L+ K A + + + + + K+ L E + + + KL T +R L
Sbjct: 325 ELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQ 384
Query: 213 DM 214
M
Sbjct: 385 FM 386
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/206 (19%), Positives = 88/206 (42%), Gaps = 5/206 (2%)
Query: 6 QELRSAKDSDDEEEVVHVDRDHFMDE--FFEQVEEIRGCIEKLSEDVEQVKKQHSAILAA 63
+++R ++ EEE + E + Q E+IR EK+ E E +++Q +
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 64 PNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLS 123
+ ++E+++ +++ K+R + K I EQEE + ++ ++ +
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR---EQEEKIREQEEMMQEQEEKMGEQE 473
Query: 124 RKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMD 183
K E + + K R + + +++ +I + E E+M++ + ++ + KM
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533
Query: 184 SQMTKQALNEIETRHNEIIKLETSIR 209
Q K E + R E E +R
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVR 559
Score = 30.8 bits (68), Expect = 1.4
Identities = 25/132 (18%), Positives = 61/132 (46%), Gaps = 7/132 (5%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDE----FFEQVEEIRGCIEKLSEDVEQVKKQ 56
++++ +++R ++ E+E + +++ M E EQ +++ EK+ E++++Q
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ 500
Query: 57 HSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRK 116
I +EK +++ E + +K + + E+ EQEE + R +R ++
Sbjct: 501 EKKIR---EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Query: 117 TQHSTLSRKFVE 128
+ K E
Sbjct: 558 VRLRQQEEKMQE 569
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 44.7 bits (104), Expect = 1e-04
Identities = 59/276 (21%), Positives = 125/276 (45%), Gaps = 32/276 (11%)
Query: 1 MKDRTQELRSAKDSDDEE----EVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQ 56
+KDR + L++ + D E +++ ++ EQ E R E+L E++E +K+
Sbjct: 565 LKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE--RDDRERL-EEIESFRKE 621
Query: 57 HSAILAAPNPDEKTKQELEDLTADIKKTANKVRS-------KLKAIEQSIEQEEGLNRSS 109
+ + N + E E D+K+ A+ + S KLK++E +IEQ++ S
Sbjct: 622 NKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKE-ECSK 680
Query: 110 ADLRIRKTQH----STLSRKFVEVMTEYNATQSKYRDRC---KDRIQRQLEITGRTTTNE 162
+ +++K + S ++ +F + + + + S YRD C + + R LEI +
Sbjct: 681 LEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEK 740
Query: 163 ELEDM----LESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDM 218
+D LES L D K + + ++E + N +L +R D D
Sbjct: 741 NDKDKKIAELESLTLRHMKDQNKKVANLKHN--QQLEKKKN--AQLLEEVRRREDSMADN 796
Query: 219 AMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAV 254
+ ++ + E+++ +E +D + ++ T++++
Sbjct: 797 SQHLQIE-ELMNALE-KTRQELDATKARLASTQQSL 830
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 44.3 bits (103), Expect = 1e-04
Identities = 55/306 (17%), Positives = 123/306 (40%), Gaps = 56/306 (18%)
Query: 1 MKDRTQELRSA-KDSDD---EEEVVHVDRDHFMDEFFEQV-------EEIRGCIEKLSED 49
+ + +E+RS K+ DD EE + V+RD + E + EE++ L E
Sbjct: 1674 LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEH 1733
Query: 50 VEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEE------ 103
E + K + N +++LE +K K++ +L+ +++++
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKL 1793
Query: 104 ----------------GLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDR 147
L S+A L+ + + + + + + N TQ K + ++
Sbjct: 1794 RGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSE--MEQ 1851
Query: 148 IQRQLEITGRTTTNEELED-----------------MLESGKLAIFTDDIKMDSQMTKQA 190
+++Q++ T + E+E+ M E L + +K++ K++
Sbjct: 1852 LKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKES 1911
Query: 191 LNEIETRHNEI---IKLETSIRELHDMFVD-MAMLVESQGEMIDRIEYNVEHSVDYVERA 246
L E + R EI +K + + H VD + + + I I+ +++ S D +++
Sbjct: 1912 LQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKK 1971
Query: 247 VSDTKK 252
+ + +K
Sbjct: 1972 IQELQK 1977
Score = 36.6 bits (83), Expect = 0.026
Identities = 48/261 (18%), Positives = 123/261 (47%), Gaps = 12/261 (4%)
Query: 2 KDRTQELRSAKDSDDEEEVVHVDRDHFM--DEFFEQVE-EIRGCIEKLSEDVEQVKKQHS 58
+ + ++ + K+ D+E + + + F D ++E E+ G ++L E +++K
Sbjct: 1383 QSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAK 1442
Query: 59 AILAAPNPDEKTKQELEDLTADIKKTANK---VRSKLKAIEQSI-EQEEGLNRSSADLRI 114
E + E + L +IK+ K +LK + EQEE +N +L
Sbjct: 1443 EKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSE 1502
Query: 115 RKTQHSTLSRKFVEVMTE-YNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKL 173
++T+ ST+ ++ + + N Q Y + I++ E+ + ++ ++ ++
Sbjct: 1503 KETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDS 1562
Query: 174 AIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHD-MFVDMAMLVESQGEMIDRI 232
A+ + + KM ++T + L E + +IK + ++ + + + ++ L E+ E++ ++
Sbjct: 1563 ALQSIESKM-LELTNR-LQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKM 1620
Query: 233 EYNVEHSVDYVE-RAVSDTKK 252
+ + E +++ AV++T++
Sbjct: 1621 KESQEKEYQFLKMTAVNETQE 1641
Score = 36.2 bits (82), Expect = 0.034
Identities = 40/225 (17%), Positives = 102/225 (45%), Gaps = 31/225 (13%)
Query: 45 KLSEDVEQVKKQHSAILAAPNPDEKTKQELED-----LTADIKKT--ANKVRSKLKAIEQ 97
+LS ++++++ + N E+ K++LE+ T + +KT K++ L+ ++
Sbjct: 867 ELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKT 926
Query: 98 SIEQEEGLNRSSADLRIRKTQ-----HSTLS---------RKFVEVMTEYNATQSKYRDR 143
++++ L + L+I + Q H T++ R +E + ++ T + + +
Sbjct: 927 LTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSK 986
Query: 144 CKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEII- 202
+ + R L + T E +D + + I D K D + + + NEII
Sbjct: 987 ISEEVSRNLHMEENT---GETKDEFQQKMVGI---DKKQDLEAKNTQTLTADVKDNEIIE 1040
Query: 203 ---KLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVE 244
K+ + I+E +++ + ++ + ++ ++ N+E +++ E
Sbjct: 1041 QQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQE 1085
Score = 36.2 bits (82), Expect = 0.034
Identities = 54/246 (21%), Positives = 111/246 (45%), Gaps = 27/246 (10%)
Query: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI 60
+K+ QE + A+D + ++E+ E E V+++R EK+SE Q+ +
Sbjct: 1908 LKESLQETK-ARDLEIQQELKTARM--LSKEHKETVDKLR---EKISEKTIQISDIQKDL 1961
Query: 61 LAAPNPDEKTKQELEDLTAD---IKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKT 117
+ + +K QEL+ +K+ N K+ +EQ +Q E N S +R+
Sbjct: 1962 DKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNF 2021
Query: 118 QHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFT 177
Q L++K E + E +K RD + RI+ L++ E + + + + I
Sbjct: 2022 Q---LTKKLHESLEEIRIV-AKERDELR-RIKESLKM--------ERDQFIATLREMIAR 2068
Query: 178 DDIKMDSQMTKQALNEIETRHNEIIKLETS-IRELHDMFVDMAMLVESQGEMIDRIEYNV 236
D + K+ L++ + E ++ + S I+EL + +M + E ++R+ ++
Sbjct: 2069 DRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEM----DDHYECLNRLSLDL 2124
Query: 237 EHSVDY 242
E +++
Sbjct: 2125 EKEIEF 2130
Score = 35.0 bits (79), Expect = 0.076
Identities = 49/246 (19%), Positives = 104/246 (42%), Gaps = 23/246 (9%)
Query: 1 MKDRTQELRS-AKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSA 59
+++ E++S AK+ DD + + V + D+ E ++EI + K E E++K H
Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQEVLQSE-SDQLKENIKEI---VAKHLETEEELKVAHCC 1485
Query: 60 ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQE-EGLNRSSADLRIRKTQ 118
+ E+T EL ++ + + ++ +L+AI ++ + + + I+ Q
Sbjct: 1486 L----KEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK--Q 1539
Query: 119 HSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTD 178
S + K E+ Q K + KD + +E TN E E + +
Sbjct: 1540 ISEVQEKVNELK------QFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKE 1593
Query: 179 DIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEH 238
++K + + ++++ EI+ +E F+ M + E+Q +M + +EH
Sbjct: 1594 EMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCE-----IEH 1648
Query: 239 SVDYVE 244
+ E
Sbjct: 1649 LKEQFE 1654
Score = 30.8 bits (68), Expect = 1.4
Identities = 48/253 (18%), Positives = 104/253 (41%), Gaps = 32/253 (12%)
Query: 17 EEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELED 76
E+E + D ++ E EE+R ++L + E V ++ + + +T L +
Sbjct: 1065 EKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAE 1124
Query: 77 LTADIKKTANKVRSK----LKAIEQSIEQEEGLN----------RSSADLRIRKTQHSTL 122
+ +K+ + +++ K L E+ E ++ +N L +T+ L
Sbjct: 1125 VEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLEL 1184
Query: 123 SRKFVE-------------VMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLE 169
++K E V+ E + RD + I R++E TG T E +
Sbjct: 1185 AQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYI-REIEATGLQTKEELKIAHIH 1243
Query: 170 SGKLAIFTDDIKMD-SQMTKQALN--EIETRHNEIIKLETSIRELHDMFVDMAMLVESQG 226
+ D+++ S+ T Q +N ++E H ++ + + E ++ ++ + E+Q
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQ- 1302
Query: 227 EMIDRIEYNVEHS 239
E ++ +E E S
Sbjct: 1303 ETMNELELLTEQS 1315
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.339
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,832,466
Number of Sequences: 37866
Number of extensions: 351649
Number of successful extensions: 2863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 404
Number of HSP's that attempted gapping in prelim test: 2107
Number of HSP's gapped (non-prelim): 1013
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.