Search of human proteins with 16306591

Search of human proteins with 16306591

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16306591 F-box and leucine-rich repeat protein 9 [Homo
sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]    446   e-125
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]    446   e-125
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi...    74   1e-13
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    71   6e-13
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     71   6e-13
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]    66   3e-11
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    64   1e-10
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]      62   4e-10
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]     56   2e-08
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    54   8e-08
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ...    54   8e-08
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]    54   1e-07
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    51   7e-07
gi|254039600 F-box and leucine-rich repeat protein 17 [Homo sapi...    48   6e-06
gi|157426875 F-box and leucine-rich repeat protein 18 [Homo sapi...    48   6e-06
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ...    47   2e-05
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]    45   4e-05
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ...    45   6e-05
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    41   7e-04
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [...    41   0.001
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [...    41   0.001
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H...    38   0.008
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H...    38   0.008
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain...    36   0.030
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H...    36   0.030
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H...    36   0.030
gi|45505155 F-box protein 38 isoform a [Homo sapiens]                  36   0.030
gi|45545409 F-box protein 38 isoform b [Homo sapiens]                  36   0.030
gi|113205085 leucine rich repeat containing 31 [Homo sapiens]          35   0.051
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    33   0.20 

>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score =  446 bits (1146), Expect = e-125
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MYSSGWPAGAAEPRHGRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTK 60
           MYSSGWPAGAAEPRHGRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTK
Sbjct: 1   MYSSGWPAGAAEPRHGRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTK 60

Query: 61  DACPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVA 120
           DACPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVA
Sbjct: 61  DACPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVA 120

Query: 121 VARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQL 180
           VARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQL
Sbjct: 121 VARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQL 180

Query: 181 RVLDVATCPGINMAAVRRFQAQLPQVSCVQSRFVGGADLTLTL 223
           RVLDVATCPGINMAAVRRFQAQLPQVSCVQSRFVGGADLTLTL
Sbjct: 181 RVLDVATCPGINMAAVRRFQAQLPQVSCVQSRFVGGADLTLTL 223


>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score =  446 bits (1146), Expect = e-125
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MYSSGWPAGAAEPRHGRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTK 60
           MYSSGWPAGAAEPRHGRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTK
Sbjct: 1   MYSSGWPAGAAEPRHGRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTK 60

Query: 61  DACPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVA 120
           DACPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVA
Sbjct: 61  DACPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVA 120

Query: 121 VARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQL 180
           VARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQL
Sbjct: 121 VARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQL 180

Query: 181 RVLDVATCPGINMAAVRRFQAQLPQVSCVQSRFVGGADLTLTL 223
           RVLDVATCPGINMAAVRRFQAQLPQVSCVQSRFVGGADLTLTL
Sbjct: 181 RVLDVATCPGINMAAVRRFQAQLPQVSCVQSRFVGGADLTLTL 223


>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
           sapiens]
          Length = 300

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 57/183 (31%), Positives = 84/183 (45%), Gaps = 23/183 (12%)

Query: 16  GRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTKDACPEPQGPSLLTLR 75
           G G+   +ALG +     +L  LSLAHC  +           G  D CP           
Sbjct: 123 GCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLA-----LRGLADRCP----------- 166

Query: 76  ALQELDLTACSKLTDASLAKVLQF--LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
           AL+ELDLTAC +L D ++  + Q     LR LSL++   + D  +  +AR CP L HL L
Sbjct: 167 ALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDL 226

Query: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINM 193
           + C R+   G    A   P L+ L +  C  + E +L  +     + R +D+   P ++ 
Sbjct: 227 TGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL-----RKRGVDIDVEPPLHQ 281

Query: 194 AAV 196
           A V
Sbjct: 282 ALV 284



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 44/133 (33%), Positives = 69/133 (51%), Gaps = 3/133 (2%)

Query: 77  LQELDLTACSK-LTDASLAKVL-QFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALS 134
           LQEL L  C + L+D  L  VL +  QLR ++L    +L+   L A+A GCP L+ L+L+
Sbjct: 89  LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLA 148

Query: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ-ACRQLRVLDVATCPGINM 193
           HC  +        A   P L+ L+L++C QL ++ +  + Q     LR L +A    +  
Sbjct: 149 HCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGD 208

Query: 194 AAVRRFQAQLPQV 206
           AAV+      P++
Sbjct: 209 AAVQELARNCPEL 221


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
          Length = 436

 Score = 71.2 bits (173), Expect = 6e-13
 Identities = 40/135 (29%), Positives = 72/135 (53%), Gaps = 1/135 (0%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQL-RQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L+ LDL +C+ +T+ SL  + +   L  QL++S   ++T +G+ A+ RGC  L+ L L  
Sbjct: 145 LRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKG 204

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
           C++L D+      +  P L  LNL +C Q+ ++ L  I + C +L+ L  + C  I  A 
Sbjct: 205 CTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAI 264

Query: 196 VRRFQAQLPQVSCVQ 210
           +       P++  ++
Sbjct: 265 LNALGQNCPRLRILE 279



 Score = 69.3 bits (168), Expect = 2e-12
 Identities = 39/115 (33%), Positives = 63/115 (54%), Gaps = 1/115 (0%)

Query: 75  RALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
           R ++ L+L  C+K TDA+   + +F  +LR L L+    +T+  L A++ GCP LE L +
Sbjct: 117 RNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNI 176

Query: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
           S C +++  G          L+ L L  C+QL ++ L  IG  C +L  L++ TC
Sbjct: 177 SWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTC 231



 Score = 67.4 bits (163), Expect = 9e-12
 Identities = 44/129 (34%), Positives = 69/129 (53%), Gaps = 4/129 (3%)

Query: 77  LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           LQ L  + CS +TDA L  + Q   +LR L ++   +LTD G   +AR C  LE + L  
Sbjct: 249 LQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEE 308

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ-ACR--QLRVLDVATCPGIN 192
           C +++D    Q +   PRLQ L+LS C  + +  +  +G  AC   QL V+++  CP I 
Sbjct: 309 CVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLIT 368

Query: 193 MAAVRRFQA 201
            A++   ++
Sbjct: 369 DASLEHLKS 377



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 49/185 (26%), Positives = 85/185 (45%), Gaps = 11/185 (5%)

Query: 33  SQLASLSLAHCSSLKSR---------PELEHQASGTKDACPEPQGPSLLT-LRALQELDL 82
           S+L  L LA C+S+ +          P LE       D   +    +L+     L+ L L
Sbjct: 143 SKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFL 202

Query: 83  TACSKLTDASLAKV-LQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSD 141
             C++L D +L  +     +L  L+L    ++TD GL+ + RGC  L+ L  S CS ++D
Sbjct: 203 KGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITD 262

Query: 142 KGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQA 201
                   + PRL+ L ++ CSQL +     + + C +L  +D+  C  I  + + +   
Sbjct: 263 AILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSI 322

Query: 202 QLPQV 206
             P++
Sbjct: 323 HCPRL 327



 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 35/134 (26%), Positives = 73/134 (54%), Gaps = 5/134 (3%)

Query: 77  LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L+ L++  CS+LTD     + +   +L ++ L    ++TD+ L+ ++  CP L+ L+LSH
Sbjct: 275 LRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSH 334

Query: 136 CSRLSDKG---WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGIN 192
           C  ++D G       A +  +L+ + L +C  + + +L+ + ++C  L  +++  C  I 
Sbjct: 335 CELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHL-KSCHSLERIELYDCQQIT 393

Query: 193 MAAVRRFQAQLPQV 206
            A ++R +  LP +
Sbjct: 394 RAGIKRLRTHLPNI 407



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 46/154 (29%), Positives = 75/154 (48%), Gaps = 13/154 (8%)

Query: 46  LKSRPELEHQASGTKDA-CPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFL-QLR 103
           LK   +LE +A     A CPE           L  L+L  C ++TD  L  + +   +L+
Sbjct: 202 LKGCTQLEDEALKYIGAHCPE-----------LVTLNLQTCLQITDEGLITICRGCHKLQ 250

Query: 104 QLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCS 163
            L  S    +TD  L A+ + CP L  L ++ CS+L+D G+   A +   L+ ++L  C 
Sbjct: 251 SLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECV 310

Query: 164 QLIEQTLDAIGQACRQLRVLDVATCPGINMAAVR 197
           Q+ + TL  +   C +L+VL ++ C  I    +R
Sbjct: 311 QITDSTLIQLSIHCPRLQVLSLSHCELITDDGIR 344



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 32/131 (24%), Positives = 65/131 (49%), Gaps = 1/131 (0%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L++L L  C  + D +L    Q  + +  L+L+   + TD    ++++ C  L HL L+ 
Sbjct: 93  LRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLAS 152

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
           C+ +++      +   P L+ LN+S C Q+ +  + A+ + C  L+ L +  C  +   A
Sbjct: 153 CTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEA 212

Query: 196 VRRFQAQLPQV 206
           ++   A  P++
Sbjct: 213 LKYIGAHCPEL 223



 Score = 30.8 bits (68), Expect = 0.97
 Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 29/108 (26%)

Query: 77  LQELDLTACSKLTDASLAKV-LQFLQLRQLSLSLLPELTDNGLVAVARG----------- 124
           L+++DL  C ++TD++L ++ +   +L+ LSLS    +TD+G+  +  G           
Sbjct: 301 LEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIE 360

Query: 125 -----------------CPSLEHLALSHCSRLSDKGWAQAASSWPRLQ 155
                            C SLE + L  C +++  G  +  +  P ++
Sbjct: 361 LDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIK 408



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 13/96 (13%)

Query: 34  QLASLSLAHCSSLKSRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACSKLTDASL 93
           +L  LSL+HC  L +   + H  +G   AC   Q         L+ ++L  C  +TDASL
Sbjct: 326 RLQVLSLSHCE-LITDDGIRHLGNG---ACAHDQ---------LEVIELDNCPLITDASL 372

Query: 94  AKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLE 129
             +     L ++ L    ++T  G+  +    P+++
Sbjct: 373 EHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIK 408


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 71.2 bits (173), Expect = 6e-13
 Identities = 39/136 (28%), Positives = 76/136 (55%), Gaps = 1/136 (0%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L+ LDLT+C  +T++SL  + +  + L  L+LS   ++T +G+ A+ RGC  L+ L L  
Sbjct: 132 LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRG 191

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
           C++L D+      +    L  LNL SCS++ ++ +  I + C +L+ L ++ C  +  A+
Sbjct: 192 CTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDAS 251

Query: 196 VRRFQAQLPQVSCVQS 211
           +       P++  +++
Sbjct: 252 LTALGLNCPRLQILEA 267



 Score = 70.9 bits (172), Expect = 8e-13
 Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 1/136 (0%)

Query: 75  RALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
           R L+ L L  C++L D +L  +  +  +L  L+L     +TD G+V + RGC  L+ L L
Sbjct: 182 RGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCL 241

Query: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINM 193
           S CS L+D        + PRLQ L  + CS L +     + + C +L  +D+  C  I  
Sbjct: 242 SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITD 301

Query: 194 AAVRRFQAQLPQVSCV 209
           + + +     P++  +
Sbjct: 302 STLIQLSIHCPKLQAL 317



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 29/159 (18%)

Query: 77  LQELDLTACSKLTDASLAKV-LQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           LQ L L+ CS LTDASL  + L   +L+ L  +    LTD G   +AR C  LE + L  
Sbjct: 236 LQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEE 295

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQA------------------- 176
           C  ++D    Q +   P+LQ L+LS C  + +  +  +  +                   
Sbjct: 296 CILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLIT 355

Query: 177 ---------CRQLRVLDVATCPGINMAAVRRFQAQLPQV 206
                    CR L  L++  C  +  A ++R +AQLP V
Sbjct: 356 DVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHV 394



 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 1/118 (0%)

Query: 75  RALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
           R ++ L+L  C+K+TD++   + +F  +L+ L L+    +T++ L  ++ GC +LE+L L
Sbjct: 104 RNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNL 163

Query: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGI 191
           S C +++  G          L+ L L  C+QL ++ L  I   C +L  L++ +C  I
Sbjct: 164 SWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRI 221



 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 35/113 (30%), Positives = 61/113 (53%), Gaps = 1/113 (0%)

Query: 77  LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L  L+L +CS++TD  + ++ +   +L+ L LS    LTD  L A+   CP L+ L  + 
Sbjct: 210 LVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAAR 269

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
           CS L+D G+   A +   L+ ++L  C  + + TL  +   C +L+ L ++ C
Sbjct: 270 CSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHC 322



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 34/125 (27%), Positives = 67/125 (53%), Gaps = 1/125 (0%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L++L L  C  + D+SL    Q  + +  L+L+   ++TD+   +++R C  L+HL L+ 
Sbjct: 80  LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
           C  +++      +     L++LNLS C Q+ +  ++A+ + CR L+ L +  C  +   A
Sbjct: 140 CVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEA 199

Query: 196 VRRFQ 200
           ++  Q
Sbjct: 200 LKHIQ 204


>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
          Length = 418

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 42/129 (32%), Positives = 69/129 (53%), Gaps = 8/129 (6%)

Query: 76  ALQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALS 134
           +L+ L+L+ C ++TD+SL ++ Q+L+ L  L L     +T+ GL+ +A G   L+ L L 
Sbjct: 118 SLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLR 177

Query: 135 HCSRLSDKG-------WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVAT 187
            C  LSD G          AA     L+ L L  C +L + +L  I +    LR+L+++ 
Sbjct: 178 SCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSF 237

Query: 188 CPGINMAAV 196
           C GI+ A +
Sbjct: 238 CGGISDAGL 246



 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 43/149 (28%), Positives = 69/149 (46%), Gaps = 9/149 (6%)

Query: 77  LQELDLTACSKLTDASL--AKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALS 134
           ++ L+L+ C  LTD  L  A V +   LR L+LSL  ++TD+ L  +A+    LE L L 
Sbjct: 92  IESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELG 151

Query: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD-------AIGQACRQLRVLDVAT 187
            CS +++ G    A    RL+ LNL SC  L +  +        +  + C  L  L +  
Sbjct: 152 GCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQD 211

Query: 188 CPGINMAAVRRFQAQLPQVSCVQSRFVGG 216
           C  +   +++     L  +  +   F GG
Sbjct: 212 CQKLTDLSLKHISRGLTGLRLLNLSFCGG 240



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 49/192 (25%), Positives = 83/192 (43%), Gaps = 20/192 (10%)

Query: 34  QLASLSLAHCSSLKSRPELEHQASGTKDACPEPQGPSLLTLRALQEL------------- 80
           +L SL+L  C  L S   + H A  T+ A     G   LTL+  Q+L             
Sbjct: 170 RLKSLNLRSCRHL-SDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLT 228

Query: 81  -----DLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
                +L+ C  ++DA L  +     LR L+L     ++D G++ +A G   L  L +S 
Sbjct: 229 GLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSF 288

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
           C ++ D+  A  A     L+ L+L SC  + +  ++ + +    LR L++  C  I    
Sbjct: 289 CDKVGDQSLAYIAQGLDGLKSLSLCSC-HISDDGINRMVRQMHGLRTLNIGQCVRITDKG 347

Query: 196 VRRFQAQLPQVS 207
           +      L Q++
Sbjct: 348 LELIAEHLSQLT 359



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 52/201 (25%), Positives = 87/201 (43%), Gaps = 19/201 (9%)

Query: 15  HGRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTKDA-------CPEPQ 67
           H  G   + A GC+      L  L+L  C  L     L+H + G           C    
Sbjct: 189 HLAGMTRSAAEGCLG-----LEQLTLQDCQKLTDL-SLKHISRGLTGLRLLNLSFCGGIS 242

Query: 68  GPSLLTLR---ALQELDLTACSKLTDASLAKV-LQFLQLRQLSLSLLPELTDNGLVAVAR 123
              LL L    +L+ L+L +C  ++D  +  + +  L+L  L +S   ++ D  L  +A+
Sbjct: 243 DAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQ 302

Query: 124 GCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVL 183
           G   L+ L+L  C  +SD G  +       L+ LN+  C ++ ++ L+ I +   QL  +
Sbjct: 303 GLDGLKSLSLCSC-HISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGI 361

Query: 184 DVATCPGINMAAVRRFQAQLP 204
           D+  C  I    + R   QLP
Sbjct: 362 DLYGCTRITKRGLERI-TQLP 381



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 35/105 (33%), Positives = 48/105 (45%), Gaps = 13/105 (12%)

Query: 100 LQLRQLSLSLLPELTDNG------------LVAVARGCPSLEHLALSHCSRLSDKGWAQA 147
           L LR+ + SL P L   G            L  V +G  ++E L LS C  L+D G   A
Sbjct: 52  LHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHA 111

Query: 148 -ASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGI 191
                  L+ LNLS C Q+ + +L  I Q  + L VL++  C  I
Sbjct: 112 FVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNI 156


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 37/132 (28%), Positives = 71/132 (53%), Gaps = 1/132 (0%)

Query: 75  RALQELDLTACSKLTDASL-AKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
           + L+EL ++ C ++TD  + A     L L  L +S   +L+D  + A+A  C +L  L++
Sbjct: 554 KKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSI 613

Query: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINM 193
           + C +++D      ++    L  L++S C  L +Q L+ +   C+QLR+L +  C  I+ 
Sbjct: 614 AGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISK 673

Query: 194 AAVRRFQAQLPQ 205
            A +R  +++ Q
Sbjct: 674 KAAQRMSSKVQQ 685



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 49/208 (23%), Positives = 81/208 (38%), Gaps = 52/208 (25%)

Query: 47  KSRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQ---FLQLR 103
           K+ P L H          +    SL  L+ L  L+L  C ++ D  L + L     +++R
Sbjct: 423 KNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIR 482

Query: 104 QLSLSLLPELTDNGLVAVARGCPSLEHLAL------------------------------ 133
           +L+LS    L+D  ++ ++  CP+L +L+L                              
Sbjct: 483 ELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDI 542

Query: 134 -------------------SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIG 174
                              S C R++D G      S   L+HL++S CSQL +  + A+ 
Sbjct: 543 SNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALA 602

Query: 175 QACRQLRVLDVATCPGINMAAVRRFQAQ 202
             C  L  L +A CP I  +A+    A+
Sbjct: 603 IYCINLTSLSIAGCPKITDSAMEMLSAK 630



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 28/155 (18%)

Query: 75  RALQELDLTACSKLTDASLAKVLQ--------------------------FLQLRQLSLS 108
           R LQEL+++ C   TD S+  + +                          F  L+ LSL+
Sbjct: 245 RNLQELNVSDCPTFTDESMRHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLA 304

Query: 109 LLPELTDNGL--VAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLI 166
                TD GL  + +  GC  L +L LS C+++S +G+   A+S   + HL ++    L 
Sbjct: 305 YCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLT 364

Query: 167 EQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQA 201
           +  + A+ + C ++  L     P I+    R   A
Sbjct: 365 DNCVKALVEKCSRITSLVFTGAPHISDCTFRALSA 399



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 31/140 (22%), Positives = 70/140 (50%), Gaps = 8/140 (5%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHC 136
           +  L  T    ++D +  + L   +LR++       +TD     + +  P+L H+ ++ C
Sbjct: 378 ITSLVFTGAPHISDCTF-RALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADC 436

Query: 137 SRLSDKGWAQAASSWPRLQHLNLSSCSQL----IEQTLDAIGQACRQLRVLDVATCPGIN 192
             ++D    ++ S   +L  LNL++C ++    ++Q LD  G A  ++R L+++ C  ++
Sbjct: 437 KGITDSS-LRSLSPLKQLTVLNLANCVRIGDMGLKQFLD--GPASMRIRELNLSNCVRLS 493

Query: 193 MAAVRRFQAQLPQVSCVQSR 212
            A+V +   + P ++ +  R
Sbjct: 494 DASVMKLSERCPNLNYLSLR 513



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 28/137 (20%), Positives = 50/137 (36%), Gaps = 27/137 (19%)

Query: 88  LTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQA 147
           + D  +   LQ  +L  L L+    L           C +L+ L +S C   +D+     
Sbjct: 207 IPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHI 266

Query: 148 ASSWP-------------------------RLQHLNLSSCSQLIEQTLD--AIGQACRQL 180
           +   P                          LQ+L+L+ C +  ++ L    +G  C +L
Sbjct: 267 SEGCPGVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKL 326

Query: 181 RVLDVATCPGINMAAVR 197
             LD++ C  I++   R
Sbjct: 327 IYLDLSGCTQISVQGFR 343


>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
          Length = 491

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 1/114 (0%)

Query: 77  LQELDLTACSKLTDASLAK-VLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L  L L  C +LTD  L   V+    +++LS+S    ++D GL  +A+    L +L+++H
Sbjct: 300 LTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAH 359

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCP 189
           C R++D G    A    +L++LN   C  + +  ++ + + C +L+ LD+  CP
Sbjct: 360 CGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCP 413



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 36/117 (30%), Positives = 61/117 (52%), Gaps = 1/117 (0%)

Query: 76  ALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALS 134
           +++ LD+T C  L D  L  +     QL  L L     LTD GL  +   C S++ L++S
Sbjct: 273 SIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVS 332

Query: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGI 191
            C  +SD G  + A    RL++L+++ C ++ +  +  + + C +LR L+   C GI
Sbjct: 333 DCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGI 389



 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 2/122 (1%)

Query: 77  LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L+ L +  C ++TD  +  V ++  +LR L+      +TD+G+  +A+ C  L+ L +  
Sbjct: 352 LRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGK 411

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
           C  +SD G    A +   L+ L+L SC  +  Q L  +   C  L+ L+V  C  +++ A
Sbjct: 412 CPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCE-VSVEA 470

Query: 196 VR 197
           +R
Sbjct: 471 LR 472



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 9/130 (6%)

Query: 77  LQELDLTACSKLTDASLAKVLQF---------LQLRQLSLSLLPELTDNGLVAVARGCPS 127
           L+ LD++ CSK+T  SL +             + +R L ++    L D GL  +A  C  
Sbjct: 240 LEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQ 299

Query: 128 LEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVAT 187
           L HL L  C RL+D+G          ++ L++S C  + +  L  I +   +LR L +A 
Sbjct: 300 LTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAH 359

Query: 188 CPGINMAAVR 197
           C  +    +R
Sbjct: 360 CGRVTDVGIR 369



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 30/117 (25%), Positives = 61/117 (52%), Gaps = 1/117 (0%)

Query: 76  ALQELDLTACSKLTDASLAKVLQF-LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALS 134
           +++EL ++ C  ++D  L ++ +   +LR LS++    +TD G+  VA+ C  L +L   
Sbjct: 325 SIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNAR 384

Query: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGI 191
            C  ++D G    A +  +L+ L++  C  + +  L+ +   C  L+ L + +C  I
Sbjct: 385 GCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESI 441



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 39/150 (26%), Positives = 73/150 (48%), Gaps = 12/150 (8%)

Query: 77  LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L+ + ++ C +LTD  L  + Q   +LR+L +S    +++  +  V   CP+LEHL +S 
Sbjct: 188 LETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSG 247

Query: 136 CSRLSDKGWAQAAS--------SWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVAT 187
           CS+++     + AS            +++L+++ C  L ++ L  I   C QL  L +  
Sbjct: 248 CSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRR 307

Query: 188 CPGINMAAVRR---FQAQLPQVSCVQSRFV 214
           C  +    +R    + A + ++S    RFV
Sbjct: 308 CVRLTDEGLRYLVIYCASIKELSVSDCRFV 337



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 24/66 (36%), Positives = 38/66 (57%)

Query: 100 LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNL 159
           L L  +++S    LTD GL  +A+ CP L  L +S C  +S++      S  P L+HL++
Sbjct: 186 LMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDV 245

Query: 160 SSCSQL 165
           S CS++
Sbjct: 246 SGCSKV 251



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 31/159 (19%)

Query: 71  LLTLRALQELDLTACSKLTDASLAKVLQFLQLRQL-----------SLSLLPEL------ 113
           L+ L +  + +  +  +L D S+ ++  FL   QL           +L+  P L      
Sbjct: 100 LIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRL 159

Query: 114 ------TDNGLVAVARG--------CPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNL 159
                  D  L  + R         C  LE + +S C RL+D+G    A   P L+ L +
Sbjct: 160 TGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEV 219

Query: 160 SSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRR 198
           S C  +  + +  +   C  L  LDV+ C  +   ++ R
Sbjct: 220 SGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTR 258


>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
          Length = 621

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 48/161 (29%), Positives = 69/161 (42%), Gaps = 31/161 (19%)

Query: 77  LQELDLTACSKLTDASLAKVL---QFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
           LQ L L +C  + D  +   +   +  +LR L L     +T+NG+  +A GCP LE L L
Sbjct: 453 LQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDL 512

Query: 134 SHCSRLSDKG--WAQAASSWPRLQHL----NLSSCSQLIE---------QTLDAIG---- 174
             C  L      + + A   P LQ L    N S C   I+         Q LD +G    
Sbjct: 513 GWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMV 572

Query: 175 ---------QACRQLRVLDVATCPGINMAAVRRFQAQLPQV 206
                    ++C+ L +LDV+ C  I+  AV    A  P+V
Sbjct: 573 SPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613



 Score = 32.3 bits (72), Expect = 0.33
 Identities = 38/108 (35%), Positives = 52/108 (48%), Gaps = 15/108 (13%)

Query: 86  SKLTDASLAKVLQFLQLRQLSLSLLP-ELTDN-GLVAVA------RGCPS-LEHLALSHC 136
           +KL D SL    +FLQ R   +  L    T N G ++VA      + C S L  L LS C
Sbjct: 330 AKLDDTSL----EFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELS-C 384

Query: 137 SRLSDKGWAQAASSW-PRLQHLNLSSCSQLIEQTLDAIGQACRQLRVL 183
           S   ++   +  S   P LQ LNLSSC +L  Q  + I + C   R++
Sbjct: 385 SHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLKRLV 432


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 46/170 (27%), Positives = 83/170 (48%), Gaps = 36/170 (21%)

Query: 68  GPSLLTLRALQELDLTACSKLTDASLAKV------LQFLQLRQ----------------- 104
           GP+ + +R   EL+L+ C +L+DAS+ K+      L +L LR                  
Sbjct: 475 GPASMRIR---ELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS 531

Query: 105 -LSLSLL-PELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQH------ 156
            +S+ L   ++++ GL  ++R    L+ L++S C R++D G     S+   L        
Sbjct: 532 LVSIDLSGTDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQITDSAMEMLSAKCHYLH 590

Query: 157 -LNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQAQLPQ 205
            L++S C  L +Q L+ +   C+QLR+L +  C  I+  A +R  +++ Q
Sbjct: 591 ILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKVQQ 640



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 28/155 (18%)

Query: 75  RALQELDLTACSKLTDASLAKVLQ--------------------------FLQLRQLSLS 108
           R LQEL+++ C   TD S+  + +                          F  L+ LSL+
Sbjct: 245 RNLQELNVSDCPTFTDESMRHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLA 304

Query: 109 LLPELTDNGL--VAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLI 166
                TD GL  + +  GC  L +L LS C+++S +G+   A+S   + HL ++    L 
Sbjct: 305 YCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLT 364

Query: 167 EQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQA 201
           +  + A+ + C ++  L     P I+    R   A
Sbjct: 365 DNCVKALVEKCSRITSLVFTGAPHISDCTFRALSA 399



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 31/140 (22%), Positives = 70/140 (50%), Gaps = 8/140 (5%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHC 136
           +  L  T    ++D +  + L   +LR++       +TD     + +  P+L H+ ++ C
Sbjct: 378 ITSLVFTGAPHISDCTF-RALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADC 436

Query: 137 SRLSDKGWAQAASSWPRLQHLNLSSCSQL----IEQTLDAIGQACRQLRVLDVATCPGIN 192
             ++D    ++ S   +L  LNL++C ++    ++Q LD  G A  ++R L+++ C  ++
Sbjct: 437 KGITDSS-LRSLSPLKQLTVLNLANCVRIGDMGLKQFLD--GPASMRIRELNLSNCVRLS 493

Query: 193 MAAVRRFQAQLPQVSCVQSR 212
            A+V +   + P ++ +  R
Sbjct: 494 DASVMKLSERCPNLNYLSLR 513



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 28/137 (20%), Positives = 50/137 (36%), Gaps = 27/137 (19%)

Query: 88  LTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQA 147
           + D  +   LQ  +L  L L+    L           C +L+ L +S C   +D+     
Sbjct: 207 IPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHI 266

Query: 148 ASSWP-------------------------RLQHLNLSSCSQLIEQTLD--AIGQACRQL 180
           +   P                          LQ+L+L+ C +  ++ L    +G  C +L
Sbjct: 267 SEGCPGVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKL 326

Query: 181 RVLDVATCPGINMAAVR 197
             LD++ C  I++   R
Sbjct: 327 IYLDLSGCTQISVQGFR 343


>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
           sapiens]
          Length = 258

 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 5/112 (4%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQLRQLSLSLLP----ELTDNGLVAVARGCPSLEHLA 132
           +Q LDL +C  ++DA+L  +    +L++L+L+        +T  G+ AVA  C  L   +
Sbjct: 63  VQTLDLRSCD-ISDAALLHLSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEAS 121

Query: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLD 184
           L  C  L+D+G    A +   L+ ++L  C  + + +L A+G+ C  L+ +D
Sbjct: 122 LKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVD 173



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 9/162 (5%)

Query: 33  SQLASLSLAHCSSLKSRPELEHQASGTKDACPEPQGPSLLTLRA--LQELDLTACSKLTD 90
           S  A L L++C  LK   +L   AS         +G   +      L E  L  C  LTD
Sbjct: 74  SDAALLHLSNCRKLK---KLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTD 130

Query: 91  ASL-AKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAAS 149
             + A  L    L+ + L     +TD  L A+ + CP L+ +  S  +++SD G     S
Sbjct: 131 EGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFS-ATQVSDSGVIALVS 189

Query: 150 S--WPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCP 189
                +L+ +++  C  L +  ++A+   C Q+R+L    CP
Sbjct: 190 GPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCP 231



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 8/109 (7%)

Query: 72  LTLRALQELDLTACSKLTDASL---AKVLQFLQLRQLSLSLLPELTDNGLVAVARG--CP 126
           L  + L+ +DL  C  +TD SL    K   FLQ    S +   +++D+G++A+  G    
Sbjct: 138 LNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFSAT---QVSDSGVIALVSGPCAK 194

Query: 127 SLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ 175
            LE + + HC  L+D       +  P+++ L    C  + + + + + Q
Sbjct: 195 KLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVLEQ 243



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 8/143 (5%)

Query: 71  LLTLRALQELDLTAC-----SKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGC 125
           L   R L++L+L A      S  ++   A       L + SL     LTD G+VA+A  C
Sbjct: 81  LSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNC 140

Query: 126 PSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAI--GQACRQLRVL 183
             L+ + L  C  ++D        + P LQ ++ S+ +Q+ +  + A+  G   ++L  +
Sbjct: 141 QLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFSA-TQVSDSGVIALVSGPCAKKLEEI 199

Query: 184 DVATCPGINMAAVRRFQAQLPQV 206
            +  C  +   AV       PQ+
Sbjct: 200 HMGHCVNLTDGAVEAVLTYCPQI 222


>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
          Length = 479

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 37/122 (30%), Positives = 61/122 (50%), Gaps = 3/122 (2%)

Query: 77  LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVA-VARGCPSLEHLALS 134
           +  L ++ C  + D ++A + Q L  L +LSL     +TD  L    AR   S   L L 
Sbjct: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAY-HVTDTALAYFTARQGHSTHTLRLL 302

Query: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMA 194
            C  +++ G      S P L  L+LS CS++ +  ++ + +  R+LR LD++ CP I   
Sbjct: 303 SCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDM 362

Query: 195 AV 196
           A+
Sbjct: 363 AL 364



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 49/167 (29%), Positives = 73/167 (43%), Gaps = 16/167 (9%)

Query: 27  CMHGAPSQLASLSLAHCSSLKSRPELEHQASGTKDAC----PEPQGPSLLTLRALQELDL 82
           C++ A   +A++S      L +  EL  QA    D         QG S  TLR L     
Sbjct: 252 CINVADDAIAAIS----QLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLL----- 302

Query: 83  TACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSD 141
            +C ++T+  +  V+  L  L  LSLS   ++TD+G+  VA     L  L LS C R++D
Sbjct: 303 -SCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITD 361

Query: 142 KGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
                 A    RL+ L L  C ++ +  L  +      LR L +  C
Sbjct: 362 MALEYVACDLHRLEELVLDRCVRITDTGLSYL-STMSSLRSLYLRWC 407



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 49/193 (25%), Positives = 71/193 (36%), Gaps = 39/193 (20%)

Query: 28  MHGAPSQLASLSLAHCSSLKS------RPELEHQASGTKDACPEPQGPSL----LTLRAL 77
           +H  P+ L +LSL+ CS +           L    S     CP     +L      L  L
Sbjct: 316 VHSLPN-LTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRL 374

Query: 78  QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137
           +EL L  C ++TD  L+ +     LR L L    ++ D GL  +         LAL    
Sbjct: 375 EELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHL---------LALGSLR 425

Query: 138 RLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVR 197
            LS  G        P L    LS   QL            ++L  L++  CPG      +
Sbjct: 426 LLSPAG-------CPLLTTTGLSGLVQL------------QELEELELTNCPGATPELFK 466

Query: 198 RFQAQLPQVSCVQ 210
            F   LP+   ++
Sbjct: 467 YFSQHLPRCLVIE 479


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 52/173 (30%), Positives = 72/173 (41%), Gaps = 43/173 (24%)

Query: 74  LRALQELDLTACSKLTDASLAKV----LQFLQLR--------QLSLSLLP---------- 111
           L+ LQEL L+ CS L+ ++L       L+ L LR        QL   LLP          
Sbjct: 507 LQGLQELVLSGCSWLSVSALGSAPLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTE 566

Query: 112 ----------------ELTDNGLVAVARGCPSLEHLALSHCSRLSDKG----WAQAASSW 151
                           ELTD  L  + R  P L  L LSHC+ + D       A  +   
Sbjct: 567 SRGRLQGVAELRLAGLELTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLR 626

Query: 152 PRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQAQLP 204
             L HLNL+ C +L +  L  + + C +LR LD+ +C  ++  A  R  A  P
Sbjct: 627 ETLVHLNLAGCHRLTDHCL-PLFRRCPRLRRLDLRSCRQLSPEACARLAAAGP 678


>gi|254039600 F-box and leucine-rich repeat protein 17 [Homo
           sapiens]
          Length = 303

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 23/76 (30%), Positives = 39/76 (51%)

Query: 113 LTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDA 172
           ++DNG+  +A  CP L       C +LSD      AS  P LQ +++ +  +L ++ L  
Sbjct: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60

Query: 173 IGQACRQLRVLDVATC 188
           +G  CR+L+ +    C
Sbjct: 61  LGSKCRELKDIHFGQC 76



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 1/105 (0%)

Query: 85  CSKLTDASLAKVLQFLQLRQ-LSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKG 143
           C +L+D S+  V     L Q + +    +LTD GL  +   C  L+ +    C ++SD+G
Sbjct: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83

Query: 144 WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
               A    +LQ + +     + +Q++ A  + C +L+ +    C
Sbjct: 84  MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGC 128



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 22/98 (22%), Positives = 51/98 (52%)

Query: 112 ELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171
           +L+D  ++AVA  CP L+ + + +  +L+D+G  Q  S    L+ ++   C ++ ++ + 
Sbjct: 26  QLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMI 85

Query: 172 AIGQACRQLRVLDVATCPGINMAAVRRFQAQLPQVSCV 209
            I + C +L+ + +     +   +V+ F    P++  V
Sbjct: 86  VIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYV 123



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 26/96 (27%), Positives = 51/96 (53%), Gaps = 5/96 (5%)

Query: 77  LQELDLTACSKLTDASLAKVLQF-LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           L+EL L +C K+TD +L  + ++ + +  + +    E+TD G   +A+   SL +L L  
Sbjct: 196 LKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMR 254

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171
           C ++++    Q    +P   H+  S+  Q  ++TL+
Sbjct: 255 CDKVNEVTVEQLVQQYP---HITFSTVLQDCKRTLE 287



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 21/88 (23%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 77  LQELDLTACSKLTDASLAKV-LQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
           LQ++ +    KLTD  L ++  +  +L+ +      +++D G++ +A+GC  L+ + +  
Sbjct: 42  LQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQE 101

Query: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCS 163
              ++D+     A   P LQ++    CS
Sbjct: 102 NKLVTDQSVKAFAEHCPELQYVGFMGCS 129



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 18/64 (28%), Positives = 36/64 (56%)

Query: 112 ELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171
           ++TD  L+A+ R   ++E + +  C  ++D+G    A S   L++L L  C ++ E T++
Sbjct: 205 KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVE 264

Query: 172 AIGQ 175
            + Q
Sbjct: 265 QLVQ 268



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 26/139 (18%), Positives = 57/139 (41%), Gaps = 25/139 (17%)

Query: 75  RALQELDLTACSKLTDASLAKVLQ-FLQLRQLSLSLLPELTDNGLVAVARGCPSLEH--- 130
           R L+++    C K++D  +  + +  L+L+++ +     +TD  + A A  CP L++   
Sbjct: 66  RELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGF 125

Query: 131 ---------------------LALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQT 169
                                L L H + L ++   +       L  LNL     + ++ 
Sbjct: 126 MGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRC 185

Query: 170 LDAIGQACRQLRVLDVATC 188
           ++ I +  + L+ L + +C
Sbjct: 186 VEVIAKEGQNLKELYLVSC 204


>gi|157426875 F-box and leucine-rich repeat protein 18 [Homo
           sapiens]
          Length = 718

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 57/208 (27%), Positives = 87/208 (41%), Gaps = 48/208 (23%)

Query: 44  SSLKSRPELEH-QASGTKDACPEPQGPSLLTLRALQELDLTACSK---LTDASLAKVLQF 99
           S LK+ P LEH +  G+  +   P+    +         L  CS+   + D+ +A + Q 
Sbjct: 477 SLLKNLPFLEHLELIGSNFSSAMPRNEPAI------RNSLPPCSRAQSVGDSEVAAIGQL 530

Query: 100 LQLRQLSLSLLPE-LTDNGLVAVARGCPSLEHLALS-------------------HCSRL 139
             LR L+L+ LP  LT +GLV +   C  L  L+L+                   HC RL
Sbjct: 531 AFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRL 590

Query: 140 SD-----------KGWAQAASSWPRLQHLNLSSCSQLIE-QTLDAIGQACRQLRVL---- 183
            D             + QA S  P LQ L L S S  ++   + A    C Q+ +     
Sbjct: 591 RDLRLEQPYFSANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFT 650

Query: 184 --DVATCPGINMAAVRRFQAQLPQVSCV 209
              +ATC  +  + +R FQA+ P ++ V
Sbjct: 651 GESLATCKSLQQSLLRSFQAERPALNVV 678


>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 410

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 17/177 (9%)

Query: 28  MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86
           +HG  SQ + L       L+ S P +   A  +        G S  +  ALQ L L++CS
Sbjct: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256

Query: 87  KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132
           +L + +L+    F +             + QL+LS     L  + L  + R CP+L HL 
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316

Query: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCP 189
           LS    L +  + Q       LQHL+LS C  +I +TL  + +A  ++R+     CP
Sbjct: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCP 372


>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
          Length = 1162

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 5/96 (5%)

Query: 112  ELTDNGLVAVARGCPSLEHLALSHCSRLSDKG----WAQAASSWPRLQHLNLSSCSQLIE 167
            ++TD  L  + R  P L  L LSHCS L+D+      A  +S+   L  LN++ C++L +
Sbjct: 1050 DITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTD 1109

Query: 168  QTLDAIGQACRQLRVLDVATCPGINMAAVRRFQAQL 203
            QTL  + +    + ++D+  C  I   A   F + L
Sbjct: 1110 QTLIYL-RRIANVTLIDLRGCKQITRKACEHFISDL 1144



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 27/101 (26%)

Query: 35   LASLSLAHCSSLKSRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACSKLTDASLA 94
            L+ L L+HCS L  +      A G+             T  +L EL++  C+KLTD +L 
Sbjct: 1066 LSRLDLSHCSHLTDQSSNLLTAVGSS------------TRYSLTELNMAGCNKLTDQTL- 1112

Query: 95   KVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
                 + LR+++   L +L         RGC  +   A  H
Sbjct: 1113 -----IYLRRIANVTLIDL---------RGCKQITRKACEH 1139


>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 424

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 48/163 (29%), Positives = 73/163 (44%), Gaps = 17/163 (10%)

Query: 28  MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86
           +HG  SQ + L       L+ S P +   A  +        G S  +  ALQ L L++CS
Sbjct: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256

Query: 87  KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132
           +L + +L+    F +             + QL+LS     L  + L  + R CP+L HL 
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316

Query: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ 175
           LS    L +  + Q       LQHL+LS C  +I +TL  +G+
Sbjct: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLELGE 358



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 5/89 (5%)

Query: 100 LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNL 159
           +Q   LS S++   T +G+++    C  L++L+L    RLSD      A +   L  LNL
Sbjct: 183 VQHMDLSNSVIEVSTLHGILSQ---CSKLQNLSLEGL-RLSDPIVNTLAKN-SNLVRLNL 237

Query: 160 SSCSQLIEQTLDAIGQACRQLRVLDVATC 188
           S CS   E  L  +  +C +L  L+++ C
Sbjct: 238 SGCSGFSEFALQTLLSSCSRLDELNLSWC 266


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 4/108 (3%)

Query: 78  QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137
           +EL+  + + +  +SLA++    +LR+L LS    +   GL  +A  CP+L +L LS  +
Sbjct: 42  KELEFLSMANVELSSLARLPSLNKLRKLELS--DNIISGGLEVLAEKCPNLTYLNLSG-N 98

Query: 138 RLSDKGWAQAASSWPRLQHLNLSSCS-QLIEQTLDAIGQACRQLRVLD 184
           ++ D    +A  +   L+ L+L +C    +E   ++I +  +Q+  LD
Sbjct: 99  KIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLD 146


>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
            sapiens]
          Length = 1336

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 94   AKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKG----WAQAAS 149
            +K+   ++LR   L    ++TD  L  + R  P L  L LS+C+ ++D+      A   +
Sbjct: 1210 SKLRNIVELRLAGL----DITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTT 1265

Query: 150  SWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQAQL 203
            +   L  +NLS C+++ +Q L +  + C  +  +D+  C  +      +F A++
Sbjct: 1266 TRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGCEQFIAEM 1318


>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
            sapiens]
          Length = 1265

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 94   AKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKG----WAQAAS 149
            +K+   ++LR   L    ++TD  L  + R  P L  L LS+C+ ++D+      A   +
Sbjct: 1141 SKLRNIVELRLAGL----DITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTT 1196

Query: 150  SWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQAQL 203
            +   L  +NLS C+++ +Q L +  + C  +  +D+  C  +      +F A++
Sbjct: 1197 TRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGCEQFIAEM 1249


>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 11/139 (7%)

Query: 78  QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137
           ++ D+    +  + S+A     + + Q+   LL  L  N L  V     S++ L L++ S
Sbjct: 164 EDADIDESEESAEESIA-----ISIAQMEKRLLHGLIHNVLPYVGT---SVKTLVLAYSS 215

Query: 138 RLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIG--QACRQLRVLDVATCPGINMAA 195
            +S K   Q     P L+HL+L+  + + +   D+      C+ LR LD++ C  I   A
Sbjct: 216 AVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVA 274

Query: 196 VRRFQAQLPQVSCVQSRFV 214
           + +    L  ++  QS F+
Sbjct: 275 LEKISRALGILTSHQSGFL 293



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 86  SKLTDASLAKVLQFLQLRQLSLSLLPELTDNGL--VAVARGCPSLEHLALSHCSRLSDKG 143
           S+ +D    +VL FL     SLS   ++TD+GL  + +  G P LEHL LS C  ++  G
Sbjct: 463 SEKSDQETGRVLLFL-----SLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAG 517

Query: 144 WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
                S+ P L       C  +     D     C+ L+    A C
Sbjct: 518 LQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQCGFRACC 561



 Score = 32.3 bits (72), Expect = 0.33
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)

Query: 131 LALSHCSRLSDKGWA--QAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
           L+LS C +++D G          P L+HLNLS C  +    L  +  AC  L       C
Sbjct: 477 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYC 536

Query: 189 PGIN 192
             IN
Sbjct: 537 DNIN 540



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 11/26 (42%), Positives = 19/26 (73%)

Query: 75  RALQELDLTACSKLTDASLAKVLQFL 100
           ++L+ LDL+ C K+TD +L K+ + L
Sbjct: 257 QSLRHLDLSGCEKITDVALEKISRAL 282


>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 11/139 (7%)

Query: 78  QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137
           ++ D+    +  + S+A     + + Q+   LL  L  N L  V     S++ L L++ S
Sbjct: 290 EDADIDESEESAEESIA-----ISIAQMEKRLLHGLIHNVLPYVGT---SVKTLVLAYSS 341

Query: 138 RLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIG--QACRQLRVLDVATCPGINMAA 195
            +S K   Q     P L+HL+L+  + + +   D+      C+ LR LD++ C  I   A
Sbjct: 342 AVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVA 400

Query: 196 VRRFQAQLPQVSCVQSRFV 214
           + +    L  ++  QS F+
Sbjct: 401 LEKISRALGILTSHQSGFL 419



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 86  SKLTDASLAKVLQFLQLRQLSLSLLPELTDNGL--VAVARGCPSLEHLALSHCSRLSDKG 143
           S+ +D    +VL FL     SLS   ++TD+GL  + +  G P LEHL LS C  ++  G
Sbjct: 589 SEKSDQETGRVLLFL-----SLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAG 643

Query: 144 WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
                S+ P L       C  +     D     C+ L+    A C
Sbjct: 644 LQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQCGFRACC 687



 Score = 32.3 bits (72), Expect = 0.33
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)

Query: 131 LALSHCSRLSDKGWA--QAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
           L+LS C +++D G          P L+HLNLS C  +    L  +  AC  L       C
Sbjct: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYC 662

Query: 189 PGIN 192
             IN
Sbjct: 663 DNIN 666



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 11/26 (42%), Positives = 19/26 (73%)

Query: 75  RALQELDLTACSKLTDASLAKVLQFL 100
           ++L+ LDL+ C K+TD +L K+ + L
Sbjct: 383 QSLRHLDLSGCEKITDVALEKISRAL 408


>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain
           and proline-rich containing [Homo sapiens]
          Length = 1435

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 39/111 (35%), Positives = 48/111 (43%), Gaps = 8/111 (7%)

Query: 5   GWPAGAAEPRHGRGRELAQALGCMHGAPSQL-ASLSLAHCSSLKSRPELEHQASGTKD-A 62
           GW  G A+ R GRG  L    G  +  P QL A++S   C+SL       +  S TK  A
Sbjct: 391 GWMTGRADWRAGRG-GLGPPAGVANSLPPQLFAAVSRGCCTSLTHLDASRNVFSRTKSRA 449

Query: 63  CPEPQGPSLLTLRALQELDLTACSKLTDASLAKVLQFL----QLRQLSLSL 109
            P      L   R L+ L L  C KL   +L  +L  L     LR L L L
Sbjct: 450 APAALQLFLSRARTLRHLGLAGC-KLPPDALRALLDGLALNTHLRDLHLDL 499


>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
           sapiens]
          Length = 533

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 101 QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLS 160
           +L  L LS    +T + LV +A+ C  L  L L H    S    +    +  R++ L L+
Sbjct: 215 RLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLT 274

Query: 161 SCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAV 196
             SQ        +G  C QL+VL+V+T  GIN  ++
Sbjct: 275 YSSQTTAILGALLGSCCPQLQVLEVST--GINRNSI 308



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 5/88 (5%)

Query: 98  QFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL--SHCSRLSDKGWAQAASSWPRLQ 155
           Q   LR L+L  LP+    G VA   G PSLE L L  S C+ +S++   +     P L+
Sbjct: 323 QLQVLRLLNLMWLPKPPGRG-VAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLR 381

Query: 156 HLNLSSCSQLIEQTLDAIGQACRQLRVL 183
            L+L  C+++    L  +   CR+L  L
Sbjct: 382 LLDLRGCARITPAGLQDL--PCRELEQL 407



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 5/86 (5%)

Query: 105 LSLSLLPELTDNGLVAVARGCPSLEHLA---LSHCSRLSDKGWAQ--AASSWPRLQHLNL 159
           LS  L+      G+ A  +   SLE L     S   RL+   W         PRL  L L
Sbjct: 162 LSSPLVGRPAKGGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKL 221

Query: 160 SSCSQLIEQTLDAIGQACRQLRVLDV 185
           S C  +    L  + +AC QL  LD+
Sbjct: 222 SGCHGVTADALVMLAKACCQLHSLDL 247



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 17/126 (13%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQLRQLSLSL------LPELTDNGLVAVARGCPSLEH 130
           L+ LDL  C+++T A L + L   +L QL L L      L    +       + C +L  
Sbjct: 380 LRLLDLRGCARITPAGL-QDLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRE 438

Query: 131 LALSHCSRLSDKGWAQA--------ASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRV 182
           L LS     S+K   QA          S P L  LNL   +++   T+ ++  +C  L  
Sbjct: 439 LDLSG-QGFSEKDLEQALAAFLSTPGGSHPALCSLNLRG-TRVTPSTVSSVISSCPGLLY 496

Query: 183 LDVATC 188
           L++ +C
Sbjct: 497 LNLESC 502



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 120 AVARGCPSLEHLALSHCSRLSDKGWAQAASS--WPRLQHLNLSS--CSQLIEQTLDAIGQ 175
           A+ +GCP L+ L L +   L        A    +P L+ L L+S  C+ +  + L  +  
Sbjct: 316 ALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLH 375

Query: 176 ACRQLRVLDVATCPGINMAAVR 197
               LR+LD+  C  I  A ++
Sbjct: 376 GSPNLRLLDLRGCARITPAGLQ 397


>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
           sapiens]
          Length = 539

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 101 QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLS 160
           +L  L LS    +T + LV +A+ C  L  L L H    S    +    +  R++ L L+
Sbjct: 221 RLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLT 280

Query: 161 SCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAV 196
             SQ        +G  C QL+VL+V+T  GIN  ++
Sbjct: 281 YSSQTTAILGALLGSCCPQLQVLEVST--GINRNSI 314



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 5/88 (5%)

Query: 98  QFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL--SHCSRLSDKGWAQAASSWPRLQ 155
           Q   LR L+L  LP+    G VA   G PSLE L L  S C+ +S++   +     P L+
Sbjct: 329 QLQVLRLLNLMWLPKPPGRG-VAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLR 387

Query: 156 HLNLSSCSQLIEQTLDAIGQACRQLRVL 183
            L+L  C+++    L  +   CR+L  L
Sbjct: 388 LLDLRGCARITPAGLQDL--PCRELEQL 413



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 17/126 (13%)

Query: 77  LQELDLTACSKLTDASLAKVLQFLQLRQLSLSL------LPELTDNGLVAVARGCPSLEH 130
           L+ LDL  C+++T A L + L   +L QL L L      L    +       + C +L  
Sbjct: 386 LRLLDLRGCARITPAGL-QDLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRE 444

Query: 131 LALSHCSRLSDKGWAQA--------ASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRV 182
           L LS     S+K   QA          S P L  LNL   +++   T+ ++  +C  L  
Sbjct: 445 LDLSG-QGFSEKDLEQALAAFLSTPGGSHPALCSLNLRG-TRVTPSTVSSVISSCPGLLY 502

Query: 183 LDVATC 188
           L++ +C
Sbjct: 503 LNLESC 508



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 120 AVARGCPSLEHLALSHCSRLSDKGWAQAASS--WPRLQHLNLSS--CSQLIEQTLDAIGQ 175
           A+ +GCP L+ L L +   L        A    +P L+ L L+S  C+ +  + L  +  
Sbjct: 322 ALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLH 381

Query: 176 ACRQLRVLDVATCPGINMAAVR 197
               LR+LD+  C  I  A ++
Sbjct: 382 GSPNLRLLDLRGCARITPAGLQ 403



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 152 PRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDV 185
           PRL  L LS C  +    L  + +AC QL  LD+
Sbjct: 220 PRLTFLKLSGCHGVTADALVMLAKACCQLHSLDL 253


>gi|45505155 F-box protein 38 isoform a [Homo sapiens]
          Length = 1113

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 113 LTDNGLVAVARGCPSLEHLALSHCSRLSDK-GWAQAASSWPRLQHLNLSSCSQLIEQTLD 171
           +TD G+ AV      +++LA+ +C  L +   W    S W RL  +NL  C  L    LD
Sbjct: 387 ITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHAL---KLD 443

Query: 172 AIGQACRQLRVLD 184
           + GQ    L  L+
Sbjct: 444 SFGQFIELLPSLE 456


>gi|45545409 F-box protein 38 isoform b [Homo sapiens]
          Length = 1188

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 113 LTDNGLVAVARGCPSLEHLALSHCSRLSDK-GWAQAASSWPRLQHLNLSSCSQLIEQTLD 171
           +TD G+ AV      +++LA+ +C  L +   W    S W RL  +NL  C  L    LD
Sbjct: 387 ITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHAL---KLD 443

Query: 172 AIGQACRQLRVLD 184
           + GQ    L  L+
Sbjct: 444 SFGQFIELLPSLE 456


>gi|113205085 leucine rich repeat containing 31 [Homo sapiens]
          Length = 552

 Score = 35.0 bits (79), Expect = 0.051
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 7/103 (6%)

Query: 65  EPQGPSLLTLRALQELDLTACSKLTD--ASLAKVLQFLQ-LRQLSLSLLPEL--TDNGLV 119
           E     L+ L+ LQ LDL  CS   D   SL +V+  L  L++L LS   ++  +   L+
Sbjct: 300 EDSPAQLVMLKHLQVLDLHQCSLTADDVMSLTQVIPLLSNLQELDLSANKKMGSSSENLL 359

Query: 120 AVARGCPSLEHLALSHCSRLSD--KGWAQAASSWPRLQHLNLS 160
           +  R  P+L+ L +++C+  S+     A+A+     L+  NLS
Sbjct: 360 SRLRFLPALKSLVINNCALESETFTALAEASVHLSALEVFNLS 402


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 33.1 bits (74), Expect = 0.20
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 78  QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137
           +EL+  +   +   S+A + +  +L++L LS        GL  +A  CP+L HL LS  +
Sbjct: 42  EELEFLSTINVGLTSIANLPKLNKLKKLELS--DNRVSGGLEVLAEKCPNLTHLNLSG-N 98

Query: 138 RLSDKGWAQAASSWPRLQHLNLSSC 162
           ++ D    +       L+ L+L +C
Sbjct: 99  KIKDLSTIEPLKKLENLKSLDLFNC 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.130    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,531,769
Number of Sequences: 37866
Number of extensions: 357146
Number of successful extensions: 1399
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1178
Number of HSP's gapped (non-prelim): 154
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.