Guide to the Human Genome
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Search of human proteins with 16306548

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16306548 seryl-tRNA synthetase [Homo sapiens]
         (514 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16306548 seryl-tRNA synthetase [Homo sapiens]                     1032   0.0  
gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo sap...   168   1e-41
gi|225579074 seryl-tRNA synthetase 2 isoform a precursor [Homo s...   168   1e-41
gi|197304746 RUN domain containing 3B isoform c [Homo sapiens]         36   0.096
gi|197304744 RUN domain containing 3B isoform b [Homo sapiens]         36   0.096
gi|19923090 RUN domain containing 3B isoform a [Homo sapiens]          36   0.096
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi...    33   0.48 
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ...    33   0.62 
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s...    33   0.62 
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    32   1.4  
gi|19923586 nuclear receptor binding SET domain protein 1 isofor...    32   1.4  
gi|62241040 leucine rich repeat containing 8 family, member A [H...    32   1.8  
gi|187829877 leucine rich repeat containing 8 family, member A [...    32   1.8  
gi|187829871 leucine rich repeat containing 8 family, member A [...    32   1.8  
gi|66529203 hypothetical protein LOC57714 [Homo sapiens]               32   1.8  
gi|4503765 fragile X mental retardation 1 [Homo sapiens]               31   2.4  
gi|148612870 chromodomain helicase DNA binding protein 1-like [H...    31   2.4  
gi|77812672 exosome component 9 isoform 1 [Homo sapiens]               30   4.0  
gi|77812670 exosome component 9 isoform 2 [Homo sapiens]               30   4.0  
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa...    30   5.3  
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa...    30   5.3  
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa...    30   5.3  
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa...    30   5.3  
gi|33356172 nibrin [Homo sapiens]                                      29   9.0  
gi|20070344 threonyl-tRNA synthetase 2, mitochondrial [Homo sapi...    29   9.0  
gi|61102725 la related protein isoform 2 [Homo sapiens]                29   9.0  
gi|39725634 la related protein isoform 1 [Homo sapiens]                29   9.0  

>gi|16306548 seryl-tRNA synthetase [Homo sapiens]
          Length = 514

 Score = 1032 bits (2669), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLC 60
           MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLC
Sbjct: 1   MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLC 60

Query: 61  SKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAE 120
           SKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAE
Sbjct: 61  SKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAE 120

Query: 121 RIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGF 180
           RIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGF
Sbjct: 121 RIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGF 180

Query: 181 EGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQL 240
           EGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQL
Sbjct: 181 EGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQL 240

Query: 241 SQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTC 300
           SQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTC
Sbjct: 241 SQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTC 300

Query: 301 FRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYH 360
           FRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYH
Sbjct: 301 FRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYH 360

Query: 361 IVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKV 420
           IVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKV
Sbjct: 361 IVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKV 420

Query: 421 EFVHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEP 480
           EFVHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEP
Sbjct: 421 EFVHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEP 480

Query: 481 SKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDA 514
           SKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDA
Sbjct: 481 SKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDA 514


>gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo
           sapiens]
          Length = 518

 Score =  168 bits (425), Expect = 1e-41
 Identities = 101/342 (29%), Positives = 178/342 (52%), Gaps = 18/342 (5%)

Query: 123 KLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVR--KKYSHVDLVVMVDGF 180
           +LE + +    ++ N  HP VP+ ++     +V  + GD  V   +   H+++   +D  
Sbjct: 158 QLEEQFYLQALKLPNQTHPDVPVGDESQA--RVLHMVGDKPVFSFQPRGHLEIGEKLDII 215

Query: 181 EGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQL 240
             ++ + V+G R Y+L+G    L+  L+ +    L  RG+ P+  P  +R  V +     
Sbjct: 216 RQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMT 275

Query: 241 SQFD-EELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLST 299
              +  ++Y +        D   + +  L  T+E  +A    D  +   DLP++    ST
Sbjct: 276 PNANPSQIYNI--------DPARFKDLNLAGTAEVGLAGYFMDHTVAFRDLPVRMVCSST 327

Query: 300 CFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPY 359
           C+R E  + G++ RG++RVH F K+E F  + P   +S ++ EE ++   E    LG+ +
Sbjct: 328 CYRAETNT-GQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHF 386

Query: 360 HIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDK 419
            ++++ +  L   A +K D+EAW PG G F E+ S SNCTD+Q+RRL I + QT+    +
Sbjct: 387 RVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMF-QTE--AGE 443

Query: 420 VEFVHMLNATMCATTRTICAILE-NYQTEKGITVPEKLKEFM 460
           ++F H +NAT CA  R + A+LE N Q +  + VP  L+ ++
Sbjct: 444 LQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPALQSYL 485


>gi|225579074 seryl-tRNA synthetase 2 isoform a precursor [Homo
           sapiens]
          Length = 520

 Score =  168 bits (425), Expect = 1e-41
 Identities = 101/342 (29%), Positives = 178/342 (52%), Gaps = 18/342 (5%)

Query: 123 KLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVR--KKYSHVDLVVMVDGF 180
           +LE + +    ++ N  HP VP+ ++     +V  + GD  V   +   H+++   +D  
Sbjct: 160 QLEEQFYLQALKLPNQTHPDVPVGDESQA--RVLHMVGDKPVFSFQPRGHLEIGEKLDII 217

Query: 181 EGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQL 240
             ++ + V+G R Y+L+G    L+  L+ +    L  RG+ P+  P  +R  V +     
Sbjct: 218 RQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMT 277

Query: 241 SQFD-EELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLST 299
              +  ++Y +        D   + +  L  T+E  +A    D  +   DLP++    ST
Sbjct: 278 PNANPSQIYNI--------DPARFKDLNLAGTAEVGLAGYFMDHTVAFRDLPVRMVCSST 329

Query: 300 CFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPY 359
           C+R E  + G++ RG++RVH F K+E F  + P   +S ++ EE ++   E    LG+ +
Sbjct: 330 CYRAETNT-GQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHF 388

Query: 360 HIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDK 419
            ++++ +  L   A +K D+EAW PG G F E+ S SNCTD+Q+RRL I + QT+    +
Sbjct: 389 RVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMF-QTE--AGE 445

Query: 420 VEFVHMLNATMCATTRTICAILE-NYQTEKGITVPEKLKEFM 460
           ++F H +NAT CA  R + A+LE N Q +  + VP  L+ ++
Sbjct: 446 LQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPALQSYL 487


>gi|197304746 RUN domain containing 3B isoform c [Homo sapiens]
          Length = 407

 Score = 35.8 bits (81), Expect = 0.096
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 183 EKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPI---YTPFFMRKEVMQEVAQ 239
           E GA+V G     L G+L+ L      + L+  G  G  P    YTP+    + +Q    
Sbjct: 157 EDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL---KYIQSSDS 213

Query: 240 LSQFDEELYKVIGKGSEKSDDNSYDEKYLI 269
           +S  +EEL  +   GSE S   +    +L+
Sbjct: 214 ISSDEEELRTLGSSGSESSTPENVGPPFLM 243


>gi|197304744 RUN domain containing 3B isoform b [Homo sapiens]
          Length = 456

 Score = 35.8 bits (81), Expect = 0.096
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 183 EKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPI---YTPFFMRKEVMQEVAQ 239
           E GA+V G     L G+L+ L      + L+  G  G  P    YTP+    + +Q    
Sbjct: 157 EDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL---KYIQSSDS 213

Query: 240 LSQFDEELYKVIGKGSEKSDDNSYDEKYLI 269
           +S  +EEL  +   GSE S   +    +L+
Sbjct: 214 ISSDEEELRTLGSSGSESSTPENVGPPFLM 243


>gi|19923090 RUN domain containing 3B isoform a [Homo sapiens]
          Length = 473

 Score = 35.8 bits (81), Expect = 0.096
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 183 EKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPI---YTPFFMRKEVMQEVAQ 239
           E GA+V G     L G+L+ L      + L+  G  G  P    YTP+    + +Q    
Sbjct: 174 EDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL---KYIQSSDS 230

Query: 240 LSQFDEELYKVIGKGSEKSDDNSYDEKYLI 269
           +S  +EEL  +   GSE S   +    +L+
Sbjct: 231 ISSDEEELRTLGSSGSESSTPENVGPPFLM 260


>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo
           sapiens]
          Length = 1369

 Score = 33.5 bits (75), Expect = 0.48
 Identities = 24/76 (31%), Positives = 38/76 (50%)

Query: 34  DQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTAD 93
           ++L K ++   R  F A  LNKLK    +       K+E   D E   EN++S +D +A 
Sbjct: 477 EELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSAL 536

Query: 94  ALANLKVSQIKKVRLL 109
           +L +  V  ++ VR L
Sbjct: 537 SLESANVEDLEPVRNL 552


>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
           sapiens]
          Length = 1004

 Score = 33.1 bits (74), Expect = 0.62
 Identities = 18/66 (27%), Positives = 31/66 (46%)

Query: 431 CATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKKQHEG 490
           C  + T    +  ++  +     E  ++ M PGL +L   V P P  ++ +   KKQ E 
Sbjct: 565 CPASYTRFTTMLKHERARHENTEEPRRQEMDPGLSKLAFLVSPVPFRRKKNSAPKKQTEK 624

Query: 491 SKKKAA 496
           +K KA+
Sbjct: 625 AKCKAS 630


>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 1100

 Score = 33.1 bits (74), Expect = 0.62
 Identities = 18/66 (27%), Positives = 31/66 (46%)

Query: 431 CATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKKQHEG 490
           C  + T    +  ++  +     E  ++ M PGL +L   V P P  ++ +   KKQ E 
Sbjct: 661 CPASYTRFTTMLKHERARHENTEEPRRQEMDPGLSKLAFLVSPVPFRRKKNSAPKKQTEK 720

Query: 491 SKKKAA 496
           +K KA+
Sbjct: 721 AKCKAS 726


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 220  YIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQP 275
            Y  I+ P   +K+V ++V ++S   EE   ++ +G   + +   DE  LI+T E+P
Sbjct: 1019 YDQIFAPKKKQKKVQEQVHKVSSRCEE-ESLLARGRSSAQNKQVDENSLISTKEEP 1073


>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
            [Homo sapiens]
          Length = 2696

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 220  YIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQP 275
            Y  I+ P   +K+V ++V ++S   EE   ++ +G   + +   DE  LI+T E+P
Sbjct: 1288 YDQIFAPKKKQKKVQEQVHKVSSRCEE-ESLLARGRSSAQNKQVDENSLISTKEEP 1342


>gi|62241040 leucine rich repeat containing 8 family, member A [Homo
           sapiens]
          Length = 810

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 51  DNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLI 110
           D L +LK L    +   + K   V  D  V    LS ++   +    + ++ +KK+  L 
Sbjct: 538 DGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINN---EGTKLIVLNSLKKMANLT 594

Query: 111 DEAILKCDAERIKLEAERFENLREI 135
           +  +++CD ERI        NL+EI
Sbjct: 595 ELELIRCDLERIPHSIFSLHNLQEI 619


>gi|187829877 leucine rich repeat containing 8 family, member A
           [Homo sapiens]
          Length = 810

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 51  DNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLI 110
           D L +LK L    +   + K   V  D  V    LS ++   +    + ++ +KK+  L 
Sbjct: 538 DGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINN---EGTKLIVLNSLKKMANLT 594

Query: 111 DEAILKCDAERIKLEAERFENLREI 135
           +  +++CD ERI        NL+EI
Sbjct: 595 ELELIRCDLERIPHSIFSLHNLQEI 619


>gi|187829871 leucine rich repeat containing 8 family, member A
           [Homo sapiens]
          Length = 810

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 51  DNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLI 110
           D L +LK L    +   + K   V  D  V    LS ++   +    + ++ +KK+  L 
Sbjct: 538 DGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINN---EGTKLIVLNSLKKMANLT 594

Query: 111 DEAILKCDAERIKLEAERFENLREI 135
           +  +++CD ERI        NL+EI
Sbjct: 595 ELELIRCDLERIPHSIFSLHNLQEI 619


>gi|66529203 hypothetical protein LOC57714 [Homo sapiens]
          Length = 1063

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 13/98 (13%)

Query: 276 IAALHRDEWLRPEDLPIKYAGLS-TCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHD 334
           +A  H+D W +PED      GLS + FR+++     DT  +    QF + +Q + S    
Sbjct: 704 LAPRHKDAWRQPEDTWAALEGLSFSPFREQM----LDTSSLL---QFMREKQHLLSIDEP 756

Query: 335 -NKSWEM---FEEMITTAEEFYQSLG-IPYHIVNIVSG 367
             +SW        ++   E F + LG  P HI++ +SG
Sbjct: 757 LFRSWFSLLPLSHLVMYMENFIEHLGRFPAHILDCLSG 794


>gi|4503765 fragile X mental retardation 1 [Homo sapiens]
          Length = 632

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 75  GDDESVPENVLSFDDLTADALA---NLKVSQIKKVRLLIDEAILKCDAERIKLEAERFEN 131
           G+D+   +   SF +   D +    NL    I K   LI E + K    R+++EAE  +N
Sbjct: 266 GEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKN 325

Query: 132 LREIGNLLHPSVPISNDEDV 151
           + +   ++ P+   SN+  V
Sbjct: 326 VPQEEEIMPPNSLPSNNSRV 345


>gi|148612870 chromodomain helicase DNA binding protein 1-like [Homo
           sapiens]
          Length = 897

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 304 EVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVN 363
           EVG H  +  G  ++H  +K+  F+YS  H    +    +M+   +++    G  Y  V+
Sbjct: 337 EVGDHLTEASG--KLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVD 394

Query: 364 -IVSGSLNHAASKKLDLEAWF 383
             V G   H A K    +  F
Sbjct: 395 GSVRGEERHLAIKNFGQQPIF 415


>gi|77812672 exosome component 9 isoform 1 [Homo sapiens]
          Length = 456

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 15/138 (10%)

Query: 60  CSKTIGEKMKK-----KEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAI 114
           CSK  G K+ +      + + +D+ V +    F    A+++AN +++  K  +  ID + 
Sbjct: 250 CSKIAGVKVAEITELILKALENDQKVRKEGGKFG--FAESIANQRITAFKMEKAPIDTSD 307

Query: 115 LKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHV--- 171
           ++  AE I  EAE    +     L  P         +   VE  WGD    +K       
Sbjct: 308 VEEKAEEIIAEAEPPSEVVSTPVLWTPGT-----AQIGEGVENSWGDLEDSEKEDDEGGG 362

Query: 172 DLVVMVDGFEGEKGAVVA 189
           D  +++DG + + G  V+
Sbjct: 363 DQAIILDGIKMDTGVEVS 380


>gi|77812670 exosome component 9 isoform 2 [Homo sapiens]
          Length = 439

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 15/138 (10%)

Query: 60  CSKTIGEKMKK-----KEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAI 114
           CSK  G K+ +      + + +D+ V +    F    A+++AN +++  K  +  ID + 
Sbjct: 250 CSKIAGVKVAEITELILKALENDQKVRKEGGKFG--FAESIANQRITAFKMEKAPIDTSD 307

Query: 115 LKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHV--- 171
           ++  AE I  EAE    +     L  P         +   VE  WGD    +K       
Sbjct: 308 VEEKAEEIIAEAEPPSEVVSTPVLWTPGT-----AQIGEGVENSWGDLEDSEKEDDEGGG 362

Query: 172 DLVVMVDGFEGEKGAVVA 189
           D  +++DG + + G  V+
Sbjct: 363 DQAIILDGIKMDTGVEVS 380


>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
           sapiens]
          Length = 987

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/166 (18%), Positives = 70/166 (42%), Gaps = 13/166 (7%)

Query: 23  QEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPE 82
           QE   ++  LVD+    ++ + + R RA+ L++        + E++K +EP   +  + E
Sbjct: 325 QELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIE 384

Query: 83  NVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLE----AERFENLREIGNL 138
                  L       L+  + ++ +LL  +  L C   +++ E     E  + L+E    
Sbjct: 385 -------LEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEK 437

Query: 139 LHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEK 184
           L+  + +      +N + +   +C V  +   ++   +    +GEK
Sbjct: 438 LNEFLELERHN--NNMMAKTLEECRVTLEGLKMENGSLKSHLQGEK 481


>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
           sapiens]
          Length = 709

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/166 (18%), Positives = 70/166 (42%), Gaps = 13/166 (7%)

Query: 23  QEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPE 82
           QE   ++  LVD+    ++ + + R RA+ L++        + E++K +EP   +  + E
Sbjct: 325 QELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIE 384

Query: 83  NVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLE----AERFENLREIGNL 138
                  L       L+  + ++ +LL  +  L C   +++ E     E  + L+E    
Sbjct: 385 -------LEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEK 437

Query: 139 LHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEK 184
           L+  + +      +N + +   +C V  +   ++   +    +GEK
Sbjct: 438 LNEFLELERHN--NNMMAKTLEECRVTLEGLKMENGSLKSHLQGEK 481


>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
           sapiens]
          Length = 1068

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/166 (18%), Positives = 70/166 (42%), Gaps = 13/166 (7%)

Query: 23  QEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPE 82
           QE   ++  LVD+    ++ + + R RA+ L++        + E++K +EP   +  + E
Sbjct: 406 QELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIE 465

Query: 83  NVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLE----AERFENLREIGNL 138
                  L       L+  + ++ +LL  +  L C   +++ E     E  + L+E    
Sbjct: 466 -------LEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEK 518

Query: 139 LHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEK 184
           L+  + +      +N + +   +C V  +   ++   +    +GEK
Sbjct: 519 LNEFLELERHN--NNMMAKTLEECRVTLEGLKMENGSLKSHLQGEK 562


>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
           sapiens]
          Length = 790

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/166 (18%), Positives = 70/166 (42%), Gaps = 13/166 (7%)

Query: 23  QEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPE 82
           QE   ++  LVD+    ++ + + R RA+ L++        + E++K +EP   +  + E
Sbjct: 406 QELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIE 465

Query: 83  NVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLE----AERFENLREIGNL 138
                  L       L+  + ++ +LL  +  L C   +++ E     E  + L+E    
Sbjct: 466 -------LEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEK 518

Query: 139 LHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEK 184
           L+  + +      +N + +   +C V  +   ++   +    +GEK
Sbjct: 519 LNEFLELERHN--NNMMAKTLEECRVTLEGLKMENGSLKSHLQGEK 562


>gi|33356172 nibrin [Homo sapiens]
          Length = 754

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/93 (23%), Positives = 40/93 (43%), Gaps = 16/93 (17%)

Query: 389 FRELVSCSNCTDYQAR----RLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENY 444
           +  LV+CS+C D   +    +  ++ G         E  H++  ++  T +TICA++   
Sbjct: 110 YEPLVACSSCLDVSGKTALNQAILQLGGFTVNNWTEECTHLVMVSVKVTIKTICALI--- 166

Query: 445 QTEKGITVPEKLKEFM--------PPGLQELIP 469
              + I  PE   EF+        PP ++   P
Sbjct: 167 -CGRPIVKPEYFTEFLKAVESKKQPPQIESFYP 198


>gi|20070344 threonyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 718

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 27/150 (18%), Positives = 58/150 (38%), Gaps = 17/150 (11%)

Query: 190 GSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYK 249
           GS  +  +G  V+   AL+ +       RG+  + TP     ++ ++      + E+++ 
Sbjct: 320 GSCFFLPRGTRVY--NALVAFIRAEYAHRGFSEVKTPTLFSTKLWEQSGHWEHYQEDMFA 377

Query: 250 VIGKGSEKSDDNSYDEKYLIATSEQPIAAL----------HRDEWLRPEDLPIKYAGLST 299
           V   GS++   +  D+     T    +  +          HR    R  +LP++ A    
Sbjct: 378 VQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRPRSWR--ELPLRLADFGA 435

Query: 300 CFRQEVGSHGRDTRGIFRVHQFEKIEQFVY 329
             R E         G+ R+  F++ +  ++
Sbjct: 436 LHRAEASG---GLGGLTRLRCFQQDDAHIF 462


>gi|61102725 la related protein isoform 2 [Homo sapiens]
          Length = 1096

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 38  KADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALAN 97
           K + E+ + +   +N  K+ N+ S+   + +  + PV  ++ VP     F  +  DALAN
Sbjct: 694 KFEPEYSQIKQEVENFKKV-NMISREQFDTLTPEPPVDPNQEVPPGPPRFQQVPTDALAN 752


>gi|39725634 la related protein isoform 1 [Homo sapiens]
          Length = 1019

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 38  KADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALAN 97
           K + E+ + +   +N  K+ N+ S+   + +  + PV  ++ VP     F  +  DALAN
Sbjct: 617 KFEPEYSQIKQEVENFKKV-NMISREQFDTLTPEPPVDPNQEVPPGPPRFQQVPTDALAN 675


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,367,624
Number of Sequences: 37866
Number of extensions: 886552
Number of successful extensions: 2852
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2829
Number of HSP's gapped (non-prelim): 34
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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