Guide to the Human Genome
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Name: PDE4A Sequence: fasta or formatted (886aa) NCBI GI: 162329608
Description:

phosphodiesterase 4A isoform 1

Referenced in:

Cyclic Nucleotides

Other entries for this name:
alt prot [860aa] phosphodiesterase 4A isoform 2
alt prot [825aa] phosphodiesterase 4A isoform 3
alt prot [647aa] phosphodiesterase 4A isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.4         74           3
 C cysteine            1.2         11           1
 D aspartate           5.1         45           1
 E glutamate           8.7         77           7
 F phenylalanine       2.7         24           2
 G glycine             5.1         45           4
 H histidine           3.0         27           2
 I isoleucine          3.0         27           1
 K lysine              3.0         27           2
 L leucine            10.2         90           3
 M methionine          3.2         28           1
 N asparagine          3.0         27           2
 P proline             7.7         68           5
 Q glutamine           5.4         48           2
 R arginine            6.0         53           2
 S serine              9.9         88           2
 T threonine           6.2         55           2
 V valine              5.1         45           2
 W tryptophan          1.1         10           1
 Y tyrosine            1.9         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   phosphodiesterase 4A isoform 1 
PDE4A                 0.875   phosphodiesterase 4A isoform 3 
PDE4A                 0.874   phosphodiesterase 4A isoform 2 
PDE4A                 0.701   phosphodiesterase 4A isoform 4 
PDE4D                 0.537   phosphodiesterase 4D isoform 1 
PDE4B                 0.521   phosphodiesterase 4B isoform 1 
PDE4B                 0.521   phosphodiesterase 4B isoform 1 
PDE4B                 0.521   phosphodiesterase 4B isoform 3 
PDE4D                 0.515   phosphodiesterase 4D isoform 2 
PDE4C                 0.499   phosphodiesterase 4C isoform PDE4C-1 
PDE4C                 0.471   phosphodiesterase 4C isoform PDE4C-3 
PDE4C                 0.461   phosphodiesterase 4C isoform PDE4C-2 
PDE4B                 0.442   phosphodiesterase 4B isoform 2 
PDE1A                 0.121   phosphodiesterase 1A isoform 2 
PDE1A                 0.121   phosphodiesterase 1A isoform 1 
PDE1C                 0.119   phosphodiesterase 1C 
PDE1B                 0.118   phosphodiesterase 1B 
PDE7B                 0.109   phosphodiesterase 7B 
PDE8A                 0.108   phosphodiesterase 8A isoform 2 
PDE8A                 0.108   phosphodiesterase 8A isoform 1 
PDE8B                 0.106   phosphodiesterase 8B isoform 2 
PDE8B                 0.106   phosphodiesterase 8B isoform 4 
PDE8B                 0.106   phosphodiesterase 8B isoform 5 
PDE8B                 0.106   phosphodiesterase 8B isoform 3 
PDE8B                 0.106   phosphodiesterase 8B isoform 1 
PDE7A                 0.105   phosphodiesterase 7A isoform a 
PDE7A                 0.096   phosphodiesterase 7A isoform b 
PDE3B                 0.087   phosphodiesterase 3B 
PDE9A                 0.087   phosphodiesterase 9A isoform g 
PDE9A                 0.087   phosphodiesterase 9A isoform g 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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