Guide to the Human Genome
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Search of human proteins with 158534077

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|158534077 regulator of G-protein signaling 22 [Homo sapiens]
         (1264 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|158534077 regulator of G-protein signaling 22 [Homo sapiens]      2563   0.0  
gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens]    61   8e-09
gi|4506505 regulator of G-protein signaling 10 isoform b [Homo s...    38   0.054
gi|52694755 regulator of G-protein signaling 10 isoform a [Homo ...    38   0.054
gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]         35   0.45 
gi|41281612 zinc finger protein 828 [Homo sapiens]                     34   0.77 
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]     34   0.77 
gi|38708169 sorting nexin 25 [Homo sapiens]                            34   0.77 
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]       34   1.0  
gi|148235002 TBC1 domain family, member 26 [Homo sapiens]              33   1.7  
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]    33   1.7  
gi|110349719 titin isoform N2-A [Homo sapiens]                         33   2.3  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      33   2.3  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      33   2.3  
gi|110349715 titin isoform N2-B [Homo sapiens]                         33   2.3  
gi|51173735 ras responsive element binding protein 1 isoform 2 [...    33   2.3  
gi|51173737 ras responsive element binding protein 1 isoform 1 [...    33   2.3  
gi|18640750 regulator of G-protein signalling 18 [Homo sapiens]        33   2.3  
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s...    32   2.9  
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         32   2.9  
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         32   2.9  
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         32   2.9  
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         32   2.9  
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         32   2.9  
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         32   2.9  
gi|85540441 regulator of G-protein signaling 21 [Homo sapiens]         32   2.9  
gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo s...    32   2.9  
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    32   2.9  
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    32   2.9  
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14...    32   2.9  

>gi|158534077 regulator of G-protein signaling 22 [Homo sapiens]
          Length = 1264

 Score = 2563 bits (6642), Expect = 0.0
 Identities = 1264/1264 (100%), Positives = 1264/1264 (100%)

Query: 1    MPEKRLTAEPPTITEEEFEDSLATDDFLVDYFNEFLSLPTFSEAIRFNADYGVFEVANDA 60
            MPEKRLTAEPPTITEEEFEDSLATDDFLVDYFNEFLSLPTFSEAIRFNADYGVFEVANDA
Sbjct: 1    MPEKRLTAEPPTITEEEFEDSLATDDFLVDYFNEFLSLPTFSEAIRFNADYGVFEVANDA 60

Query: 61   PQFLEKQLKKILQNQQPRNPIYDVVRKGKNEVKPVQMNAPDEDETINVNYNIMCLSREEG 120
            PQFLEKQLKKILQNQQPRNPIYDVVRKGKNEVKPVQMNAPDEDETINVNYNIMCLSREEG
Sbjct: 61   PQFLEKQLKKILQNQQPRNPIYDVVRKGKNEVKPVQMNAPDEDETINVNYNIMCLSREEG 120

Query: 121  IKWIKKERLPAFLESDCYFEYRLAKLVSQVRWSKSGMNFTVGSNFSPWIVKKPPSLPPPA 180
            IKWIKKERLPAFLESDCYFEYRLAKLVSQVRWSKSGMNFTVGSNFSPWIVKKPPSLPPPA
Sbjct: 121  IKWIKKERLPAFLESDCYFEYRLAKLVSQVRWSKSGMNFTVGSNFSPWIVKKPPSLPPPA 180

Query: 181  TEEDNLVIMKKFYVSLGEASYTQTKDWFALAKQSQQTVSTFSLPCCVPYNKLKSPAISSV 240
            TEEDNLVIMKKFYVSLGEASYTQTKDWFALAKQSQQTVSTFSLPCCVPYNKLKSPAISSV
Sbjct: 181  TEEDNLVIMKKFYVSLGEASYTQTKDWFALAKQSQQTVSTFSLPCCVPYNKLKSPAISSV 240

Query: 241  SENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKKQD 300
            SENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKKQD
Sbjct: 241  SENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKKQD 300

Query: 301  VDESLTMHFSTCEEFLSSYIYFILRGAIQQIVGKPVGETPDYINFNNITKVSFDDCFESI 360
            VDESLTMHFSTCEEFLSSYIYFILRGAIQQIVGKPVGETPDYINFNNITKVSFDDCFESI
Sbjct: 301  VDESLTMHFSTCEEFLSSYIYFILRGAIQQIVGKPVGETPDYINFNNITKVSFDDCFESI 360

Query: 361  HGKNFLSELVQTTKERSEEIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKK 420
            HGKNFLSELVQTTKERSEEIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKK
Sbjct: 361  HGKNFLSELVQTTKERSEEIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKK 420

Query: 421  FIKGTLGERYWWLWMDIERLKVLKDPGRHQRHLEKMKKCYLVSNGDYYLSAEILSKFKLL 480
            FIKGTLGERYWWLWMDIERLKVLKDPGRHQRHLEKMKKCYLVSNGDYYLSAEILSKFKLL
Sbjct: 421  FIKGTLGERYWWLWMDIERLKVLKDPGRHQRHLEKMKKCYLVSNGDYYLSAEILSKFKLL 480

Query: 481  DGSQWNEEHLRNIQSEVLKPLLLYWAPRFCVTHSASTKYASAELKFWHLRQAKPRKDIDP 540
            DGSQWNEEHLRNIQSEVLKPLLLYWAPRFCVTHSASTKYASAELKFWHLRQAKPRKDIDP
Sbjct: 481  DGSQWNEEHLRNIQSEVLKPLLLYWAPRFCVTHSASTKYASAELKFWHLRQAKPRKDIDP 540

Query: 541  FPQMATLLPLRPKSCIPQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSS 600
            FPQMATLLPLRPKSCIPQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSS
Sbjct: 541  FPQMATLLPLRPKSCIPQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSS 600

Query: 601  KDDVIEKGSKYMSESSKVIHLTSFTDISECLKPQLDRRYAYTEEPRVKTVSDVGALGGSD 660
            KDDVIEKGSKYMSESSKVIHLTSFTDISECLKPQLDRRYAYTEEPRVKTVSDVGALGGSD
Sbjct: 601  KDDVIEKGSKYMSESSKVIHLTSFTDISECLKPQLDRRYAYTEEPRVKTVSDVGALGGSD 660

Query: 661  MENLLQSLYVENRAGFFFTKFCEHSGNKLWKNSVYFWFDLQAYHQLFYQETLQPFKVCKQ 720
            MENLLQSLYVENRAGFFFTKFCEHSGNKLWKNSVYFWFDLQAYHQLFYQETLQPFKVCKQ
Sbjct: 661  MENLLQSLYVENRAGFFFTKFCEHSGNKLWKNSVYFWFDLQAYHQLFYQETLQPFKVCKQ 720

Query: 721  AQYLFATYVAPSATLDIGLQQEKKKEIYMKIQPPFEDLFDTAEEYILLLLLEPWTKMVKS 780
            AQYLFATYVAPSATLDIGLQQEKKKEIYMKIQPPFEDLFDTAEEYILLLLLEPWTKMVKS
Sbjct: 721  AQYLFATYVAPSATLDIGLQQEKKKEIYMKIQPPFEDLFDTAEEYILLLLLEPWTKMVKS 780

Query: 781  DQIAYKKVELVEETRQLDSTYFRKLQALHKETFSKKAEDTTCEIGTGILSLSNVSKRTEY 840
            DQIAYKKVELVEETRQLDSTYFRKLQALHKETFSKKAEDTTCEIGTGILSLSNVSKRTEY
Sbjct: 781  DQIAYKKVELVEETRQLDSTYFRKLQALHKETFSKKAEDTTCEIGTGILSLSNVSKRTEY 840

Query: 841  WDNVPAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRK 900
            WDNVPAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRK
Sbjct: 841  WDNVPAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRK 900

Query: 901  AKSIYIKNKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVEIQKHVQN 960
            AKSIYIKNKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVEIQKHVQN
Sbjct: 901  AKSIYIKNKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVEIQKHVQN 960

Query: 961  RLENVWLPLFLASEQFAARQKIKVQMKDIAEELLLQKAEKKIGVWKPVESKWISSSCKII 1020
            RLENVWLPLFLASEQFAARQKIKVQMKDIAEELLLQKAEKKIGVWKPVESKWISSSCKII
Sbjct: 961  RLENVWLPLFLASEQFAARQKIKVQMKDIAEELLLQKAEKKIGVWKPVESKWISSSCKII 1020

Query: 1021 AFRKALLNPVTSRQFQRFVALKGDLLENGLLFWQEVQKYKDLCHSHCDESVIQKKITTII 1080
            AFRKALLNPVTSRQFQRFVALKGDLLENGLLFWQEVQKYKDLCHSHCDESVIQKKITTII
Sbjct: 1021 AFRKALLNPVTSRQFQRFVALKGDLLENGLLFWQEVQKYKDLCHSHCDESVIQKKITTII 1080

Query: 1081 NCFINSSIPPALQIDIPVEQAQKIIEHRKELGPYVFREAQMTIFGVLFKFWPQFCEFRKN 1140
            NCFINSSIPPALQIDIPVEQAQKIIEHRKELGPYVFREAQMTIFGVLFKFWPQFCEFRKN
Sbjct: 1081 NCFINSSIPPALQIDIPVEQAQKIIEHRKELGPYVFREAQMTIFGVLFKFWPQFCEFRKN 1140

Query: 1141 LTDENIMSVLERRQEYNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQ 1200
            LTDENIMSVLERRQEYNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQ
Sbjct: 1141 LTDENIMSVLERRQEYNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQ 1200

Query: 1201 PYGRQPTWCYSKYIEALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLKKNMSAH 1260
            PYGRQPTWCYSKYIEALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLKKNMSAH
Sbjct: 1201 PYGRQPTWCYSKYIEALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLKKNMSAH 1260

Query: 1261 SSQK 1264
            SSQK
Sbjct: 1261 SSQK 1264


>gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens]
          Length = 1076

 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 81/356 (22%), Positives = 147/356 (41%), Gaps = 96/356 (26%)

Query: 854  SDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSIYIKNKYLNK 913
            +++L N    E FR+FL+   + + L   T +++    T    N++  KS+ I+N  + K
Sbjct: 647  TEVLLNTQHLEFFREFLKERKAKIPLQFLTAVQKISIET----NEKICKSL-IEN--VIK 699

Query: 914  KYFFGPNSPASLYQQNQVMHLSGGWGKILHE-----QLDAPVLVEIQKHVQNRLENVWL- 967
             +F G  SP  + Q +           I+ E      +    L+ +Q HV   +E  W  
Sbjct: 700  TFFQGQLSPEEMLQCD---------APIIKEIASMRHVTTSTLLTLQGHVMKSIEEKWFK 750

Query: 968  ---PLFLASEQ-FAARQKIKVQMKDIAE--ELLLQKAEKKIGVWKPVESKWISSSCKIIA 1021
                LF    Q    + ++++  +  ++     LQ+++KK   W  + S +I S CK   
Sbjct: 751  DYQDLFPPHHQEVEVQSEVQISSRKPSKIVSTYLQESQKK--GWMRMIS-FIRSFCK--- 804

Query: 1022 FRKALLNPVTSRQFQRFV--------------------------ALKGDLLENG------ 1049
            +R+ +LNP   ++F+ ++                           ++    ENG      
Sbjct: 805  YRRFMLNPSKRQEFEDYLHQEMQNSKENFTTAHNTSGRSAPPSTNVRSADQENGEITLVK 864

Query: 1050 -----------------LLFWQEVQKYKDL-----------CHSHCDESVIQKKITTIIN 1081
                             L F+ E++K+ DL            ++  D  +++ K+  I  
Sbjct: 865  RRIFGHRIITVNFAINDLYFFSEMEKFNDLVSSAHMLQVNRAYNENDVILMRSKMNIIQK 924

Query: 1082 CFINSSIPPALQIDIPVEQAQKIIEHRKE--LGPYVFREAQMTIFGVLFKFWPQFC 1135
             F+NS IPP L++++P  Q   I+    E  L   VF  A M++F V+  FW +FC
Sbjct: 925  LFLNSDIPPKLRVNVPEFQKDAILAAITEGYLDRSVFHGAIMSVFPVVMYFWKRFC 980


>gi|4506505 regulator of G-protein signaling 10 isoform b [Homo
            sapiens]
          Length = 167

 Score = 38.1 bits (87), Expect = 0.054
 Identities = 37/156 (23%), Positives = 75/156 (48%), Gaps = 19/156 (12%)

Query: 852  KFSDLLNNKLE----FEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSIYIK 907
            K++  L N LE     + FR+FL+   S  +++ W   E F+++  + + Q KAK IY+ 
Sbjct: 23   KWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYM- 81

Query: 908  NKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVE-IQKHVQNRLENVW 966
              +L+ K     +S  ++  Q+++        KIL E    P++ + +Q  + N ++   
Sbjct: 82   -TFLSSK----ASSQVNVEGQSRLNE------KILEE--PHPLMFQKLQDQIFNLMKYDS 128

Query: 967  LPLFLASEQFAARQKIKVQMKDIAEELLLQKAEKKI 1002
               FL S+ F   ++ + + +D+ +     K   +I
Sbjct: 129  YSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRI 164



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 9/113 (7%)

Query: 378 EEIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKKFIKGTLGERYWWLWMDI 437
           E I  +  SS +     +S A W  S     + + +  +RF++F+K    E     W+  
Sbjct: 2   EHIHDSDGSSSSSHQSLKSTAKWAASLENL-LEDPEGVKRFREFLKKEFSEENVLFWLAC 60

Query: 438 ERLKVLKDPGRHQRHLEKMKKCYLVSNGDYYLSAEILSKFKLLDGSQWNEEHL 490
           E  K ++D  + Q   EK K+ Y+      +LS++  S+  +   S+ NE+ L
Sbjct: 61  EDFKKMQDKTQMQ---EKAKEIYMT-----FLSSKASSQVNVEGQSRLNEKIL 105


>gi|52694755 regulator of G-protein signaling 10 isoform a [Homo
            sapiens]
          Length = 181

 Score = 38.1 bits (87), Expect = 0.054
 Identities = 37/156 (23%), Positives = 75/156 (48%), Gaps = 19/156 (12%)

Query: 852  KFSDLLNNKLE----FEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSIYIK 907
            K++  L N LE     + FR+FL+   S  +++ W   E F+++  + + Q KAK IY+ 
Sbjct: 37   KWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYM- 95

Query: 908  NKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVE-IQKHVQNRLENVW 966
              +L+ K     +S  ++  Q+++        KIL E    P++ + +Q  + N ++   
Sbjct: 96   -TFLSSK----ASSQVNVEGQSRLNE------KILEE--PHPLMFQKLQDQIFNLMKYDS 142

Query: 967  LPLFLASEQFAARQKIKVQMKDIAEELLLQKAEKKI 1002
               FL S+ F   ++ + + +D+ +     K   +I
Sbjct: 143  YSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRI 178



 Score = 34.7 bits (78), Expect = 0.59
 Identities = 29/117 (24%), Positives = 53/117 (45%), Gaps = 9/117 (7%)

Query: 374 KERSEEIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKKFIKGTLGERYWWL 433
           K    +I  +  SS +     +S A W  S     + + +  +RF++F+K    E     
Sbjct: 12  KRPPSDIHDSDGSSSSSHQSLKSTAKWAASLENL-LEDPEGVKRFREFLKKEFSEENVLF 70

Query: 434 WMDIERLKVLKDPGRHQRHLEKMKKCYLVSNGDYYLSAEILSKFKLLDGSQWNEEHL 490
           W+  E  K ++D  + Q   EK K+ Y+      +LS++  S+  +   S+ NE+ L
Sbjct: 71  WLACEDFKKMQDKTQMQ---EKAKEIYMT-----FLSSKASSQVNVEGQSRLNEKIL 119


>gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]
          Length = 487

 Score = 35.0 bits (79), Expect = 0.45
 Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 23/174 (13%)

Query: 1024 KALLNPVTSRQFQRFVALKGDLLENGLLFWQEVQKYKDLCHSHCDESVIQKKITTIINCF 1083
            +AL +PV   QF +F  L+ +     L FW  V+   DL      E  +  ++  I   F
Sbjct: 336  EALKDPVGREQFLKF--LESEFSSENLRFWLAVE---DLKKRPIKE--VPSRVQEIWQEF 388

Query: 1084 INSSIPPALQIDIPVEQAQKIIEHRKELGPYVFREAQMTIFGVL-FKFWPQFCEFRKNLT 1142
            +    P A+ +D   +   K  ++ KE G Y F +AQ  I+ ++    +P+F        
Sbjct: 389  LAPGAPSAINLDS--KSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIR------ 440

Query: 1143 DENIMSVLERRQEYNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSF 1196
                       QE  + KKK     D ++  +   Q    S+ + +   L+ S+
Sbjct: 441  -------SSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGKSLTSKRLTSLAQSY 487


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 34.3 bits (77), Expect = 0.77
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 7/93 (7%)

Query: 505 WAPRFCVTHSASTKYASAELKFWHLRQAKPRKDIDPFPQMA----TLLPLRPKSCIPQIP 560
           W P   V+ SAS K +S     W    A P       P++     TL P   K+  P  P
Sbjct: 359 WKPTPSVS-SASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSP 417

Query: 561 EIQKEEFSLSQPPKSPNKSPEVKTATQKP--WK 591
           E++K    LS   +SP  SPE++  +  P  WK
Sbjct: 418 ELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWK 450


>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
          Length = 1499

 Score = 34.3 bits (77), Expect = 0.77
 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 19/121 (15%)

Query: 530  RQAKPRKDIDPF----PQ-MATLLPLRPKSCIPQIPEIQKEEFS-----LSQPPKSPNKS 579
            R+  P KD+ PF    PQ +  +L L  +  + +  +  ++  S     LS PP SP  S
Sbjct: 1065 RKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSS 1124

Query: 580  PEVKTATQKPWKRELLYPGSSKDDVIEKGSKYMSESSKVIHLTSFTDISECLKPQLDRRY 639
            P          K   L P  + D+  + G   +S  S ++  +SF  +   L  +  +R+
Sbjct: 1125 PR---------KGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRH 1175

Query: 640  A 640
            +
Sbjct: 1176 S 1176


>gi|38708169 sorting nexin 25 [Homo sapiens]
          Length = 840

 Score = 34.3 bits (77), Expect = 0.77
 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 28/156 (17%)

Query: 845  PAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSI 904
            P   K  +F D+L N    EHF  ++E       +  W  +E  +     +  Q   + I
Sbjct: 280  PQSQKILQFEDILANTFYREHFGMYMERMDKRALISFWESVEHLKNANKNEIPQLVGE-I 338

Query: 905  YIKNKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVEIQKHVQNRLEN 964
            Y +N ++  K     +   SLY++ Q   L G  G          V  +IQ+ V   L++
Sbjct: 339  Y-QNFFVESKEI---SVEKSLYKEIQ-QCLVGNKG--------IEVFYKIQEDVYETLKD 385

Query: 965  VWLPLFLASEQFAARQKIKVQMKDIAEELLLQKAEK 1000
             + P F+ S              D+ E+LL+++ EK
Sbjct: 386  RYYPSFIVS--------------DLYEKLLIKEEEK 407


>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
          Length = 669

 Score = 33.9 bits (76), Expect = 1.0
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 521 SAELKFWHLRQAKPRKDIDPFPQMATLLPLRPKSCIPQIPEIQKEEFSLSQP-----PKS 575
           +A+   W  + ++P++D   FP+ A+  PL      P  PE+     + S+P     PK 
Sbjct: 249 AAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKR 308

Query: 576 PNKSPEVKTATQKPWKREL 594
           P +  E K  ++KP + EL
Sbjct: 309 P-RPAEFKALSKKPPQPEL 326


>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
          Length = 250

 Score = 33.1 bits (74), Expect = 1.7
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 6/80 (7%)

Query: 379 EIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKKFIKGTLGERYWWLWMDIE 438
           E++Q    SK  +   +  ADW     T     +K  +R  K I   +  R W L +DI+
Sbjct: 64  EVKQRRKESKRTNKWQKMLADWTKYRST-----KKLSQRVYKVIPLAVRGRAWSLLLDID 118

Query: 439 RLKVLKDPGRHQRHLEKMKK 458
           R+K  ++PG+++   EK K+
Sbjct: 119 RIK-SQNPGKYKVMKEKGKR 137


>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
          Length = 2608

 Score = 33.1 bits (74), Expect = 1.7
 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 13/67 (19%)

Query: 239  SVSENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKK 298
            +V E+F FDD             N   SE EE+E EEEE S  L    S AL R     K
Sbjct: 1830 AVEEDFEFDD-------------NSSFSEEEEDEEEEEEDSGPLSAEQSAALARSCAIHK 1876

Query: 299  QDVDESL 305
            +D+ + L
Sbjct: 1877 EDLRDGL 1883


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 540   PFPQMATLLPLRPKSCIPQIPEIQKEEFSLSQPPKSPNKSPEV 582
             P  ++   +P +P+S  P++PE  KE     + P +P K PEV
Sbjct: 10562 PEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEV 10604



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 557   PQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSS-KDDVIEKGSKYMSES 615
             P  PE+  +      PP  P    + K++    WK      GS  K  ++E   +  ++ 
Sbjct: 15692 PSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDW 15751

Query: 616   SKVIHLTSFTDISECLKPQLD--RRYAYTEEPRVKTVSDVGALGGSD 660
              +V          EC+ P L   R+Y +    RVK V++ G    SD
Sbjct: 15752 KRVNEPDKLITTCECVVPNLKELRKYRF----RVKAVNEAGESEPSD 15794


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 557  PQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSS-KDDVIEKGSKYMSES 615
            P  PE+  +      PP  P    + K++    WK      GS  K  ++E   +  ++ 
Sbjct: 9387 PSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDW 9446

Query: 616  SKVIHLTSFTDISECLKPQLD--RRYAYTEEPRVKTVSDVGALGGSD 660
             +V          EC+ P L   R+Y +    RVK V++ G    SD
Sbjct: 9447 KRVNEPDKLITTCECVVPNLKELRKYRF----RVKAVNEAGESEPSD 9489


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 557  PQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSS-KDDVIEKGSKYMSES 615
            P  PE+  +      PP  P    + K++    WK      GS  K  ++E   +  ++ 
Sbjct: 9320 PSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDW 9379

Query: 616  SKVIHLTSFTDISECLKPQLD--RRYAYTEEPRVKTVSDVGALGGSD 660
             +V          EC+ P L   R+Y +    RVK V++ G    SD
Sbjct: 9380 KRVNEPDKLITTCECVVPNLKELRKYRF----RVKAVNEAGESEPSD 9422


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 557  PQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSS-KDDVIEKGSKYMSES 615
            P  PE+  +      PP  P    + K++    WK      GS  K  ++E   +  ++ 
Sbjct: 9195 PSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDW 9254

Query: 616  SKVIHLTSFTDISECLKPQLD--RRYAYTEEPRVKTVSDVGALGGSD 660
             +V          EC+ P L   R+Y +    RVK V++ G    SD
Sbjct: 9255 KRVNEPDKLITTCECVVPNLKELRKYRF----RVKAVNEAGESEPSD 9297


>gi|51173735 ras responsive element binding protein 1 isoform 2
           [Homo sapiens]
          Length = 1687

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 9/114 (7%)

Query: 174 PSLPPPATEEDNLVIMKKFYVSLGEASYTQTKDWFALAKQSQQTVSTFSLPCCVPYNKLK 233
           P+ PPP      L     F V   E      K   AL +  Q+ +S  S    VPY+   
Sbjct: 874 PTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKG-LALVQVKQENISFLSPSSLVPYDCSM 932

Query: 234 SPAISSVSENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPS 287
            P   S+ +NF   D    +    PS+  K     EEE G  E+ S      PS
Sbjct: 933 EPIDLSIPKNFRKGD----KDLATPSEAKKP----EEEAGSSEQPSPCPAPGPS 978


>gi|51173737 ras responsive element binding protein 1 isoform 1
           [Homo sapiens]
          Length = 1742

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 9/114 (7%)

Query: 174 PSLPPPATEEDNLVIMKKFYVSLGEASYTQTKDWFALAKQSQQTVSTFSLPCCVPYNKLK 233
           P+ PPP      L     F V   E      K   AL +  Q+ +S  S    VPY+   
Sbjct: 874 PTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKG-LALVQVKQENISFLSPSSLVPYDCSM 932

Query: 234 SPAISSVSENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPS 287
            P   S+ +NF   D    +    PS+  K     EEE G  E+ S      PS
Sbjct: 933 EPIDLSIPKNFRKGD----KDLATPSEAKKP----EEEAGSSEQPSPCPAPGPS 978


>gi|18640750 regulator of G-protein signalling 18 [Homo sapiens]
          Length = 235

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 18/55 (32%), Positives = 29/55 (52%)

Query: 853 FSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSIYIK 907
           F  LL+++   E F +FL+T  S  ++  W   E F++     +   KAK+IY K
Sbjct: 87  FDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEK 141


>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
           sapiens]
          Length = 1662

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 40/161 (24%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 238 SSVSENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEK 297
           + V+EN IF +   PRTK DP  T+K   +  E   ++ + + SL   P  +  R Y   
Sbjct: 490 TDVNENLIFFEETRPRTKSDP--TSKSSGQGYEVVPDDFD-AASLDHEPCASRARSYTLD 546

Query: 298 KQDVDESLTMHFSTCEEFLSSYIYFILRGAIQQIVGKPVGETPDYINFNNITKVSFDDCF 357
                E+L  +  +C+  L S       G  Q   GKP G + D I   +   V+  D  
Sbjct: 547 NSLGAEALNFYCDSCKAKLQS-----SXGPSQS--GKP-GSSRDNILLYDEIPVTLIDSV 598

Query: 358 ESIHGKNFLSELVQTTKERSEEIEQTSLSSKNESAGPESRA 398
           ++   ++   EL        + +E  + S       P   A
Sbjct: 599 QTRTVRDHAQELDDALVSTLQALEALAASEDGPHPPPPQTA 639


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 72/350 (20%), Positives = 140/350 (40%), Gaps = 58/350 (16%)

Query: 951  LVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLL-------QKAEKKIG 1003
            L EI + +Q RLE+        SE  A R++++V+++    EL+        + +     
Sbjct: 437  LQEILQDLQKRLES--------SE--AERKQLQVELQSRRAELVCLNNTEISENSSDLSQ 486

Query: 1004 VWKPVESKWISSSCKIIAFRK----ALLNPVTSRQFQRFV----------ALKGDLLENG 1049
              K  +SK+  +  ++++ +K     L++P +   +  F            LK DL +N 
Sbjct: 487  KLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL-QNA 545

Query: 1050 LLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRK 1109
            L   +E ++ K+      +E +++++  T+I        PP  + +        +IE+  
Sbjct: 546  L---EESERNKEKVRE-LEEKLVEREKGTVIK-------PPVEEYEEMKSSYCSVIENMN 594

Query: 1110 ELGPYVF---REAQMTIFGVLFKFWPQFC-----------EFRKNLTDENIMSVLERRQE 1155
            +   ++F   +EAQ  I  +      Q             E    + DE    V E  Q 
Sbjct: 595  KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL 654

Query: 1156 YNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIE 1215
            Y + + +L      KS +D   +Y + +       L + S    +    +    YSK + 
Sbjct: 655  YKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN 714

Query: 1216 ALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLK-KNMSAHSSQK 1264
             L Q + L+  Q+E    +   LQ +T  + ++  M  K  N+  H + K
Sbjct: 715  ELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASK 764


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 72/350 (20%), Positives = 140/350 (40%), Gaps = 58/350 (16%)

Query: 951  LVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLL-------QKAEKKIG 1003
            L EI + +Q RLE+        SE  A R++++V+++    EL+        + +     
Sbjct: 426  LQEILQDLQKRLES--------SE--AERKQLQVELQSRRAELVCLNNTEISENSSDLSQ 475

Query: 1004 VWKPVESKWISSSCKIIAFRK----ALLNPVTSRQFQRFV----------ALKGDLLENG 1049
              K  +SK+  +  ++++ +K     L++P +   +  F            LK DL +N 
Sbjct: 476  KLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL-QNA 534

Query: 1050 LLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRK 1109
            L   +E ++ K+      +E +++++  T+I        PP  + +        +IE+  
Sbjct: 535  L---EESERNKEKVRE-LEEKLVEREKGTVIK-------PPVEEYEEMKSSYCSVIENMN 583

Query: 1110 ELGPYVF---REAQMTIFGVLFKFWPQFC-----------EFRKNLTDENIMSVLERRQE 1155
            +   ++F   +EAQ  I  +      Q             E    + DE    V E  Q 
Sbjct: 584  KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL 643

Query: 1156 YNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIE 1215
            Y + + +L      KS +D   +Y + +       L + S    +    +    YSK + 
Sbjct: 644  YKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN 703

Query: 1216 ALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLK-KNMSAHSSQK 1264
             L Q + L+  Q+E    +   LQ +T  + ++  M  K  N+  H + K
Sbjct: 704  ELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASK 753


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 72/350 (20%), Positives = 140/350 (40%), Gaps = 58/350 (16%)

Query: 951  LVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLL-------QKAEKKIG 1003
            L EI + +Q RLE+        SE  A R++++V+++    EL+        + +     
Sbjct: 405  LQEILQDLQKRLES--------SE--AERKQLQVELQSRRAELVCLNNTEISENSSDLSQ 454

Query: 1004 VWKPVESKWISSSCKIIAFRK----ALLNPVTSRQFQRFV----------ALKGDLLENG 1049
              K  +SK+  +  ++++ +K     L++P +   +  F            LK DL +N 
Sbjct: 455  KLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL-QNA 513

Query: 1050 LLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRK 1109
            L   +E ++ K+      +E +++++  T+I        PP  + +        +IE+  
Sbjct: 514  L---EESERNKEKVRE-LEEKLVEREKGTVIK-------PPVEEYEEMKSSYCSVIENMN 562

Query: 1110 ELGPYVF---REAQMTIFGVLFKFWPQFC-----------EFRKNLTDENIMSVLERRQE 1155
            +   ++F   +EAQ  I  +      Q             E    + DE    V E  Q 
Sbjct: 563  KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL 622

Query: 1156 YNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIE 1215
            Y + + +L      KS +D   +Y + +       L + S    +    +    YSK + 
Sbjct: 623  YKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN 682

Query: 1216 ALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLK-KNMSAHSSQK 1264
             L Q + L+  Q+E    +   LQ +T  + ++  M  K  N+  H + K
Sbjct: 683  ELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASK 732


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 72/350 (20%), Positives = 140/350 (40%), Gaps = 58/350 (16%)

Query: 951  LVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLL-------QKAEKKIG 1003
            L EI + +Q RLE+        SE  A R++++V+++    EL+        + +     
Sbjct: 434  LQEILQDLQKRLES--------SE--AERKQLQVELQSRRAELVCLNNTEISENSSDLSQ 483

Query: 1004 VWKPVESKWISSSCKIIAFRK----ALLNPVTSRQFQRFV----------ALKGDLLENG 1049
              K  +SK+  +  ++++ +K     L++P +   +  F            LK DL +N 
Sbjct: 484  KLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL-QNA 542

Query: 1050 LLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRK 1109
            L   +E ++ K+      +E +++++  T+I        PP  + +        +IE+  
Sbjct: 543  L---EESERNKEKVRE-LEEKLVEREKGTVIK-------PPVEEYEEMKSSYCSVIENMN 591

Query: 1110 ELGPYVF---REAQMTIFGVLFKFWPQFC-----------EFRKNLTDENIMSVLERRQE 1155
            +   ++F   +EAQ  I  +      Q             E    + DE    V E  Q 
Sbjct: 592  KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL 651

Query: 1156 YNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIE 1215
            Y + + +L      KS +D   +Y + +       L + S    +    +    YSK + 
Sbjct: 652  YKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN 711

Query: 1216 ALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLK-KNMSAHSSQK 1264
             L Q + L+  Q+E    +   LQ +T  + ++  M  K  N+  H + K
Sbjct: 712  ELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASK 761


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 72/350 (20%), Positives = 140/350 (40%), Gaps = 58/350 (16%)

Query: 951  LVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLL-------QKAEKKIG 1003
            L EI + +Q RLE+        SE  A R++++V+++    EL+        + +     
Sbjct: 434  LQEILQDLQKRLES--------SE--AERKQLQVELQSRRAELVCLNNTEISENSSDLSQ 483

Query: 1004 VWKPVESKWISSSCKIIAFRK----ALLNPVTSRQFQRFV----------ALKGDLLENG 1049
              K  +SK+  +  ++++ +K     L++P +   +  F            LK DL +N 
Sbjct: 484  KLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL-QNA 542

Query: 1050 LLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRK 1109
            L   +E ++ K+      +E +++++  T+I        PP  + +        +IE+  
Sbjct: 543  L---EESERNKEKVRE-LEEKLVEREKGTVIK-------PPVEEYEEMKSSYCSVIENMN 591

Query: 1110 ELGPYVF---REAQMTIFGVLFKFWPQFC-----------EFRKNLTDENIMSVLERRQE 1155
            +   ++F   +EAQ  I  +      Q             E    + DE    V E  Q 
Sbjct: 592  KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL 651

Query: 1156 YNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIE 1215
            Y + + +L      KS +D   +Y + +       L + S    +    +    YSK + 
Sbjct: 652  YKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN 711

Query: 1216 ALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLK-KNMSAHSSQK 1264
             L Q + L+  Q+E    +   LQ +T  + ++  M  K  N+  H + K
Sbjct: 712  ELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASK 761


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 72/350 (20%), Positives = 140/350 (40%), Gaps = 58/350 (16%)

Query: 951  LVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLL-------QKAEKKIG 1003
            L EI + +Q RLE+        SE  A R++++V+++    EL+        + +     
Sbjct: 434  LQEILQDLQKRLES--------SE--AERKQLQVELQSRRAELVCLNNTEISENSSDLSQ 483

Query: 1004 VWKPVESKWISSSCKIIAFRK----ALLNPVTSRQFQRFV----------ALKGDLLENG 1049
              K  +SK+  +  ++++ +K     L++P +   +  F            LK DL +N 
Sbjct: 484  KLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL-QNA 542

Query: 1050 LLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRK 1109
            L   +E ++ K+      +E +++++  T+I        PP  + +        +IE+  
Sbjct: 543  L---EESERNKEKVRE-LEEKLVEREKGTVIK-------PPVEEYEEMKSSYCSVIENMN 591

Query: 1110 ELGPYVF---REAQMTIFGVLFKFWPQFC-----------EFRKNLTDENIMSVLERRQE 1155
            +   ++F   +EAQ  I  +      Q             E    + DE    V E  Q 
Sbjct: 592  KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL 651

Query: 1156 YNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIE 1215
            Y + + +L      KS +D   +Y + +       L + S    +    +    YSK + 
Sbjct: 652  YKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN 711

Query: 1216 ALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLK-KNMSAHSSQK 1264
             L Q + L+  Q+E    +   LQ +T  + ++  M  K  N+  H + K
Sbjct: 712  ELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASK 761


>gi|85540441 regulator of G-protein signaling 21 [Homo sapiens]
          Length = 152

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 17/50 (34%), Positives = 26/50 (52%)

Query: 856 LLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSIY 905
           LL N+   + FR FL++  S  ++  W   E F++    D+   KAK IY
Sbjct: 25  LLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIY 74


>gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo
           sapiens]
          Length = 782

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 33/134 (24%), Positives = 49/134 (36%), Gaps = 9/134 (6%)

Query: 251 HPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKKQDVDESLTMHFS 310
           HP   KDP   +K I   +  E    E   S  D    A      +K+Q   E    HF 
Sbjct: 57  HPDKNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQREYRFRHFH 116

Query: 311 TCEEFLSSYIYFILRGAIQQIVGKP--------VGET-PDYINFNNITKVSFDDCFESIH 361
               F  S+ +F      +  + +         V E  PD      + K++ D CF  IH
Sbjct: 117 ENFYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIH 176

Query: 362 GKNFLSELVQTTKE 375
            +    E++Q  +E
Sbjct: 177 IEPVWKEVIQELEE 190


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 44/201 (21%), Positives = 79/201 (39%), Gaps = 27/201 (13%)

Query: 724 LFATYVAPSATLDIGLQQEKKKEIYMKIQPPFEDLFDTAEEYILLLLLEPWTKMVKSDQI 783
           LF  Y+   A     L  EK+KE+  + Q   E      E  +     E  TK +  ++ 
Sbjct: 818 LFKQYIEKIAK---NLDSEKEKEL--ERQARIEASLREREREVQKARSEQ-TKEIDRERE 871

Query: 784 AYKKVELVEETRQLDSTYFRKLQALHKETFSKKAEDTTCEIGTGILSLSNVSKRTEYWDN 843
            +K+ E ++  + L S   R       +T     +D   E G+    L    K   + ++
Sbjct: 872 QHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGS---LLEREEKEKLFNEH 928

Query: 844 VPAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQF-------RRITYRDR 896
           + A  K  +           EHFRQ L+  S+      W ++++         + +  DR
Sbjct: 929 IEALTKKKR-----------EHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDR 977

Query: 897 NQRKAKSIYIKNKYLNKKYFF 917
            +++    YI++KY+  K  F
Sbjct: 978 KKQREFEEYIRDKYITAKADF 998


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
            sapiens]
          Length = 1098

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 44/201 (21%), Positives = 79/201 (39%), Gaps = 27/201 (13%)

Query: 724  LFATYVAPSATLDIGLQQEKKKEIYMKIQPPFEDLFDTAEEYILLLLLEPWTKMVKSDQI 783
            LF  Y+   A     L  EK+KE+  + Q   E      E  +     E  TK +  ++ 
Sbjct: 839  LFKQYIEKIAK---NLDSEKEKEL--ERQARIEASLREREREVQKARSEQ-TKEIDRERE 892

Query: 784  AYKKVELVEETRQLDSTYFRKLQALHKETFSKKAEDTTCEIGTGILSLSNVSKRTEYWDN 843
             +K+ E ++  + L S   R       +T     +D   E G+    L    K   + ++
Sbjct: 893  QHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGS---LLEREEKEKLFNEH 949

Query: 844  VPAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQF-------RRITYRDR 896
            + A  K  +           EHFRQ L+  S+      W ++++         + +  DR
Sbjct: 950  IEALTKKKR-----------EHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDR 998

Query: 897  NQRKAKSIYIKNKYLNKKYFF 917
             +++    YI++KY+  K  F
Sbjct: 999  KKQREFEEYIRDKYITAKADF 1019


>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
           isoform 2 [Homo sapiens]
          Length = 662

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 17/157 (10%)

Query: 256 KDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKKQDVDESLTMHFSTCEEF 315
           +D S  + L  +   ++   + + +  QDTPS A+    +  +  + ++L+ H    E  
Sbjct: 346 QDTSSQDMLFHDMTSQD--MQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 403

Query: 316 LSSYIYFILRGAIQQIVGKPVGETPDYINFNN--ITKVSFDDCFESIHGKNFLSELVQTT 373
            S  + F     IQ ++ +P    P+     N  I ++S+ D           SE+++ T
Sbjct: 404 TSHIVQF---PEIQHLLQQPPDLQPENTEPQNQQILQMSYQD---------IRSEVMEET 451

Query: 374 KE-RSEEIEQTSLSSKNESAGPESRADWCISHRTYDI 409
           KE +SEE      SS+  S   +++A   +   + D+
Sbjct: 452 KEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDV 488


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,412,621
Number of Sequences: 37866
Number of extensions: 2224767
Number of successful extensions: 8397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 8228
Number of HSP's gapped (non-prelim): 227
length of query: 1264
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1150
effective length of database: 13,930,794
effective search space: 16020413100
effective search space used: 16020413100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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