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Search of human proteins with 158534059
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|158534059 formin binding protein 4 [Homo sapiens]
(1017 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|158534059 formin binding protein 4 [Homo sapiens] 2035 0.0
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 81 6e-15
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 78 5e-14
gi|110431370 espin [Homo sapiens] 74 5e-13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 73 2e-12
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 70 1e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 69 2e-11
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 67 1e-10
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 67 1e-10
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 67 1e-10
gi|153792074 proline rich 12 [Homo sapiens] 66 1e-10
gi|52485606 formin-like 2 [Homo sapiens] 66 2e-10
gi|195947369 junction-mediating and regulatory protein [Homo sap... 65 3e-10
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 65 3e-10
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 65 4e-10
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 65 4e-10
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 65 4e-10
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] 65 4e-10
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 64 6e-10
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 62 3e-09
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 59 2e-08
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 59 2e-08
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 59 2e-08
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 59 2e-08
gi|194294554 SET binding protein 1 isoform a [Homo sapiens] 58 5e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 58 5e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 58 5e-08
gi|55741677 SET domain containing 1A [Homo sapiens] 57 9e-08
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 57 9e-08
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 57 9e-08
>gi|158534059 formin binding protein 4 [Homo sapiens]
Length = 1017
Score = 2035 bits (5272), Expect = 0.0
Identities = 1017/1017 (100%), Positives = 1017/1017 (100%)
Query: 1 MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTA 60
MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTA
Sbjct: 1 MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTA 60
Query: 61 VTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDD 120
VTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDD
Sbjct: 61 VTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDD 120
Query: 121 NDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEPKE 180
NDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEPKE
Sbjct: 121 NDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEPKE 180
Query: 181 AATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNE 240
AATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNE
Sbjct: 181 AATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNE 240
Query: 241 VTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREV 300
VTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREV
Sbjct: 241 VTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREV 300
Query: 301 KKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKEEPVSEVKETST 360
KKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKEEPVSEVKETST
Sbjct: 301 KKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKEEPVSEVKETST 360
Query: 361 TVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAELRA 420
TVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAELRA
Sbjct: 361 TVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAELRA 420
Query: 421 LEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTP 480
LEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTP
Sbjct: 421 LEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTP 480
Query: 481 ENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSK 540
ENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSK
Sbjct: 481 ENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSK 540
Query: 541 FEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKG 600
FEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKG
Sbjct: 541 FEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKG 600
Query: 601 WSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSN 660
WSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSN
Sbjct: 601 WSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSN 660
Query: 661 STESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPE 720
STESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPE
Sbjct: 661 STESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPE 720
Query: 721 SPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTI 780
SPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTI
Sbjct: 721 SPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTI 780
Query: 781 SSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTI 840
SSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTI
Sbjct: 781 SSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTI 840
Query: 841 PVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTA 900
PVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTA
Sbjct: 841 PVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTA 900
Query: 901 TIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEE 960
TIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEE
Sbjct: 901 TIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEE 960
Query: 961 DNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRRKMAPNT 1017
DNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRRKMAPNT
Sbjct: 961 DNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRRKMAPNT 1017
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 80.9 bits (198), Expect = 6e-15
Identities = 69/261 (26%), Positives = 100/261 (38%), Gaps = 23/261 (8%)
Query: 705 PPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPS 764
PP P PPPPPP +PPPPPP PP + + D ++ T L+
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVST-DTSSLRRADPKGRSALLADIQQGTRLR-- 60
Query: 765 AQTTVVTSQSSVDSTISSSSSTKGIKRKATE-ISTAVVQRSATIGSSPVL--YSQSAIAT 821
+ T + +S+ S ++ +G T ST G PVL Q +A
Sbjct: 61 -KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119
Query: 822 GHQAAGIGNQATG-------IGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSY 874
G G G++A I IP + P G +A G + + AP +
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
Query: 875 AECSVPIGVTAPSLQPVQARGAVP-------TATIIEPPPP--PPPPPPPPPPAPKMPPP 925
P+ PS P++ P ++ PP P PPPPPPPPPP P PP
Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
Query: 926 EKTKKGRKDKAKKSKTKMPSL 946
+ K + + +P +
Sbjct: 240 ASVLSDKAVKPQLAPLHLPPI 260
Score = 55.5 bits (132), Expect = 3e-07
Identities = 34/104 (32%), Positives = 44/104 (42%), Gaps = 31/104 (29%)
Query: 689 LTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPP-------------------- 728
++P L + N+PV+ PP+P PPPPPPPP +PPP PP
Sbjct: 201 VSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI 260
Query: 729 -------PPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSA 765
PP G E + ++EPPAP PL P A
Sbjct: 261 PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
Score = 45.1 bits (105), Expect = 3e-04
Identities = 61/251 (24%), Positives = 77/251 (30%), Gaps = 74/251 (29%)
Query: 705 PPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGS--------EEPPAPGTE 756
PP P PPPP PP PPPPP PPP I+ + G PP P
Sbjct: 166 PPRPNVPAPPPPTPP--PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP 223
Query: 757 EDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQ 816
P P + S + S K +K + + +
Sbjct: 224 PPPPPPPPPTPPPLPPASVL--------SDKAVKPQLAPLHLPPIP-------------- 261
Query: 817 SAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMS-LQSNYLGLAAAPAIMSYA 875
+P+ P G +A S Q A P + YA
Sbjct: 262 ---------------------PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA 300
Query: 876 ECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPP----PP--------PPPPAPKMP 923
CS + AP L V + P PP PP P PP P PPAP
Sbjct: 301 SCSPRASLPAPPLPGVNSSSETP------PPLPPKSPSFQAPPQKAGAQALPAPPAPPGS 354
Query: 924 PP--EKTKKGR 932
P +K + GR
Sbjct: 355 QPFLQKKRHGR 365
Score = 43.5 bits (101), Expect = 0.001
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Query: 903 IEPPPPPPPPPP------PPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRE 956
+ PPPPPP PPP PPPP P PP + K ++ + + +++ +++
Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKV 62
Query: 957 LDEEDNSSSSEEDREST 973
D S+ E + T
Sbjct: 63 TQINDRSAPQIESSKGT 79
Score = 42.7 bits (99), Expect = 0.002
Identities = 23/63 (36%), Positives = 24/63 (38%), Gaps = 30/63 (47%)
Query: 699 NVPVLQPPLPLEMPPPPPPP------------------------------PESPPPPPPP 728
NVP PP P PPP PPP P +PPPPPPP
Sbjct: 170 NVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP 229
Query: 729 PPP 731
PPP
Sbjct: 230 PPP 232
Score = 30.4 bits (67), Expect = 8.8
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 2/36 (5%)
Query: 158 PQPAAPVGASAPPPTPPRPEPKEAATSTLSSSTSNG 193
P P P+GA PPP PP P TS+L + G
Sbjct: 12 PPPPPPLGA--PPPPPPSAPPVSTDTSSLRRADPKG 45
Score = 30.4 bits (67), Expect = 8.8
Identities = 25/96 (26%), Positives = 32/96 (33%), Gaps = 41/96 (42%)
Query: 699 NVPVLQPPLPLEMP-------------------PPPPPPPESP------------PP--- 724
++P + PPLPL P PP PPPP P PP
Sbjct: 256 HLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPG 315
Query: 725 -------PPPPPPPAEDGEIQEVEMEDEGSEEPPAP 753
PPP PP + + + + PPAP
Sbjct: 316 VNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP 351
Score = 30.4 bits (67), Expect = 8.8
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 27/106 (25%)
Query: 688 PLTPFWTLL-QSNVPVLQPPLP-----LEMPPPPPPPPES---PP--------PPPPPPP 730
PL P+ + ++++P PPLP E PPP PP S PP P PP PP
Sbjct: 295 PLPPYASCSPRASLPA--PPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352
Query: 731 PAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQ--TTVVTSQS 774
++ ++ + P A G + + P P A+ TT ++S+S
Sbjct: 353 GSQP------FLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKS 392
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 77.8 bits (190), Expect = 5e-14
Identities = 83/328 (25%), Positives = 117/328 (35%), Gaps = 45/328 (13%)
Query: 618 QSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESF 677
Q G W+ + + ++EE + +E + KDK G + +E + KE
Sbjct: 348 QGGSPCWKKQEQKLDDEEEEKKEEEE--------KDKEGEEKEERAVAEEMMPAAEKEE- 398
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPP-PPPPAEDGE 736
+ PLTP P PP PL P PPPP PPPPPP PPP
Sbjct: 399 ----AKLPPPPLTP---------PAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP 445
Query: 737 IQEVEMEDEGSEEPPAPGT----EEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRK 792
+ E E S P P T PL PS + +++ + T + +
Sbjct: 446 PPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGG 505
Query: 793 ATEISTAVVQRSATIGSS------PVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPA 846
E S V +S T + PV+ ++S+ + P P
Sbjct: 506 PPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDED---------PPKPPK 556
Query: 847 AGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTA--TIIE 904
+ R S + AP + S P P + ++ PT T +
Sbjct: 557 VEVSPVLRPPITTSPPVPQEPAP-VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLT 615
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKTKKGR 932
PPPPP PPPPPAP PP T R
Sbjct: 616 RELPPPPPAPPPPPAPSPPPAPATSSRR 643
Score = 50.1 bits (118), Expect = 1e-05
Identities = 68/294 (23%), Positives = 101/294 (34%), Gaps = 80/294 (27%)
Query: 696 LQSNVPVLQPPLPLEMPPPPPPPPES---------------------------PPPPPPP 728
+ ++ PV Q P P+ PP P PP + PPPP PP
Sbjct: 567 ITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626
Query: 729 PPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKG 788
PPPA PPAP T PL A + S
Sbjct: 627 PPPA--------------PSPPPAPATSSRRPLLLRAP--------------QFTPSEAH 658
Query: 789 IKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAG 848
+K + ++ + P S +A G N H ++P P
Sbjct: 659 LKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTN------HLSLPRFAPVVT 712
Query: 849 MGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPP 908
+A + APA+ + + A LQP+Q A+ T + + PP
Sbjct: 713 TPVKAE--------VSPHGAPALSNGPQ------TQAQLLQPLQ---ALQTQLLPQALPP 755
Query: 909 PPPPPPPPPPAPKMPPPEKTKKGRKDKAKKS--KTKMPSLVKKWQSIQRELDEE 960
P P PPP +MPP EK + S + KM SL+K+ + ++D++
Sbjct: 756 PQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQ 809
Score = 40.8 bits (94), Expect = 0.007
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 24/91 (26%)
Query: 880 PIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPP--------PPPPP------------- 918
P T+ +L P G +P ++ P PPPPPPP P PP
Sbjct: 2226 PTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFS 2285
Query: 919 --APKMPPPEKTKKGRKD-KAKKSKTKMPSL 946
+P PPP K + +D +A + ++P L
Sbjct: 2286 GRSPPAPPPYKAPRLDEDGEASEDTPQVPGL 2316
Score = 33.9 bits (76), Expect = 0.80
Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 15/46 (32%)
Query: 701 PVLQPPLPLEMPPPPPPP---PESP------------PPPPPPPPP 731
PV QPPLP + P P P P P PPPPPPP
Sbjct: 2214 PVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPP 2259
Score = 33.9 bits (76), Expect = 0.80
Identities = 34/103 (33%), Positives = 39/103 (37%), Gaps = 43/103 (41%)
Query: 685 SLMPLTPF-WTL----LQSNVPVLQPPLPLEMPPPPPPP--------PESPP-------- 723
++ P P WTL L +PV+ P PPPPPPP P SPP
Sbjct: 2223 TISPTAPTSWTLPPGPLLGVLPVVGVVRPA--PPPPPPPLTLVLSSGPASPPRQAIRVKR 2280
Query: 724 --------PPPPPPPPA----EDGEIQEVEMEDEGSEEPPAPG 754
PP PPP A EDGE E + P PG
Sbjct: 2281 VSTFSGRSPPAPPPYKAPRLDEDGEASE--------DTPQVPG 2315
Score = 33.5 bits (75), Expect = 1.0
Identities = 22/58 (37%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 704 QPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGS---EEPPAPGTEED 758
+ P PL+ P P PE PP P PP E Q E S EEPP+P +E+
Sbjct: 2347 ESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKEN 2404
Score = 33.1 bits (74), Expect = 1.4
Identities = 62/270 (22%), Positives = 90/270 (33%), Gaps = 57/270 (21%)
Query: 701 PVLQPPLPLEMPPP---------------PPPPPESPPPPPPPPPPAEDGEI----QEVE 741
P L+ L +PPP PP P SPPPP P ED E+ +
Sbjct: 1931 PPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAAD 1990
Query: 742 MEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVV 801
++ S P EE + SS + SS +++ I T +S +
Sbjct: 1991 LDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEE---SSPTSRYIHFPVTVVSAPGL 2047
Query: 802 QRSATIGSSPVLY-------SQSAIATGHQAAGIGNQATGIG------------HQTIPV 842
SAT G+ + + S Q G G +G G P
Sbjct: 2048 APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPE 2107
Query: 843 SLPA----------AGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQ 892
LP+ G G G +S L AP + + ++ S G+TA P +
Sbjct: 2108 DLPSEIVDFVLKNLGGPGDGGAGPREES----LPPAPPLANGSQPSQ--GLTASPADPTR 2161
Query: 893 ARGAVPTATIIEPPPPPPPPPPPPPPAPKM 922
+P A + P P PP P K+
Sbjct: 2162 TFAWLPGAPGVRVLSLGPAPEPPKPATSKI 2191
Score = 32.0 bits (71), Expect = 3.0
Identities = 15/58 (25%), Positives = 25/58 (43%)
Query: 117 DDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPP 174
DD++ + E+ + KE + + + + +A P P P S PPP PP
Sbjct: 362 DDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPP 419
Score = 30.8 bits (68), Expect = 6.8
Identities = 24/79 (30%), Positives = 27/79 (34%), Gaps = 40/79 (50%)
Query: 693 WTLLQSNVPVLQPPLPLEMPPP---PPPPPE----------------------------S 721
WT L +P PP P PPP PPP P +
Sbjct: 611 WTSLTRELP---PPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLT 667
Query: 722 PPP------PPPPPPPAED 734
PPP P P PPPA+D
Sbjct: 668 PPPLGAPEAPEPEPPPADD 686
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 74.3 bits (181), Expect = 5e-13
Identities = 66/241 (27%), Positives = 92/241 (38%), Gaps = 43/241 (17%)
Query: 696 LQSNVPVLQPPLPLEM-----PPPPPPPPESPPPPPPP------PPPAEDGEIQEVEMED 744
+QS + +L P L L P PPPPPP PPPPPPP PPP
Sbjct: 407 IQSYMDMLNPELGLPRGTIGKPTPPPPPPSFPPPPPPPGTQLPPPPPGYP---------- 456
Query: 745 EGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRS 804
+ +PP D ++ + V +++ + +SS G++R+ + +
Sbjct: 457 --APKPPVGPQAADIYMQTKNKLRHVETEA-LKKELSSCDGHDGLRRQDSSRKPRAFSKQ 513
Query: 805 ATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLG 864
+ G Y Q G A G+ H + A G G + + + G
Sbjct: 514 PSTGD---YYRQLGRCPGETLAA----RPGMAHSEEVRARQPARAGCPRLGPAARGSLEG 566
Query: 865 LAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 924
+A P VP G A P +R E PPPPPPPPPP P A PP
Sbjct: 567 PSAPPQAALLPGNHVPNGCAA---DPKASR---------ELPPPPPPPPPPLPEAASSPP 614
Query: 925 P 925
P
Sbjct: 615 P 615
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 25/104 (24%)
Query: 845 PAAGMGHQARGMSLQSNYLGLAAAPAIMS-YAECSV----------PIGVTAPSLQPVQA 893
P +GM +S+Q L++ + +S Y CS P G+++ +Q+
Sbjct: 350 PDSGMSSPNTTVSVQPLNFDLSSPTSTLSNYDSCSSSHSSIKGQHPPCGLSSARAADIQS 409
Query: 894 ------------RGAVPTATIIEPPPPPPPPPPPPPPAPKMPPP 925
RG + T PPPPP PPPPPPP ++PPP
Sbjct: 410 YMDMLNPELGLPRGTIGKPT--PPPPPPSFPPPPPPPGTQLPPP 451
Score = 41.6 bits (96), Expect = 0.004
Identities = 60/289 (20%), Positives = 110/289 (38%), Gaps = 53/289 (18%)
Query: 701 PVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTP 760
P LP PPPPPP PE+ PPP PP + +E G P G +
Sbjct: 589 PKASRELPPPPPPPPPPLPEAASSPPPAPP---------LPLESAG----PGCGQRRSS- 634
Query: 761 LKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIA 820
SS+ STK + + + G S +
Sbjct: 635 --------------------SSTGSTKSFNMMSPTGDNSELLAEIKAGKS--------LK 666
Query: 821 TGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMS-LQSNYLGLAAAPAIMSYAECSV 879
Q+ G+ +GIG P P + + + +S ++S A +++ + V
Sbjct: 667 PTPQSKGLTTVFSGIGQ---PAFQPDSPLPSVSPALSPVRSPTPPAAGFQPLLNGSLVPV 723
Query: 880 PIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKS 939
P AP +Q + +PT + P P KM + ++ ++ K ++
Sbjct: 724 PPTTPAPGVQ-LDVEALIPTH---DEQGRPIPEWKRQVMVRKMQLKMQEEEEQRRKEEEE 779
Query: 940 KTKMPSLVKKWQS--IQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQL 986
+ ++ S+ W+ ++++L+EE EE+R+ + R E+ + ++L
Sbjct: 780 EARLASM-PAWRRDLLRKKLEEEREQKRKEEERQKQEELRREKEQSEKL 827
Score = 40.0 bits (92), Expect = 0.011
Identities = 43/153 (28%), Positives = 58/153 (37%), Gaps = 22/153 (14%)
Query: 837 HQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGA 896
H +I P G+ AR +QS Y+ M E +P G P
Sbjct: 387 HSSIKGQHPPCGLS-SARAADIQS-YMD-------MLNPELGLPRGTIGKPTPP------ 431
Query: 897 VPTATIIEPPPPPP----PPPPPPPPAPKMP-PPEKTKKGRKDKAKKSKTKMPSLVKKWQ 951
P PPPPPP PPPPP PAPK P P+ + K K + +L K+
Sbjct: 432 -PPPPSFPPPPPPPGTQLPPPPPGYPAPKPPVGPQAADIYMQTKNKLRHVETEALKKELS 490
Query: 952 SIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQ 984
S D SS + R + Q ++ +Q
Sbjct: 491 SCDGH-DGLRRQDSSRKPRAFSKQPSTGDYYRQ 522
Score = 30.8 bits (68), Expect = 6.8
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 158 PQPAAPVGASAPPPTPPRP-EPKEAATSTLSSSTSNGT 194
P P P AS+PPP PP P E SS+S G+
Sbjct: 602 PPPPLPEAASSPPPAPPLPLESAGPGCGQRRSSSSTGS 639
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 72.8 bits (177), Expect = 2e-12
Identities = 79/324 (24%), Positives = 114/324 (35%), Gaps = 40/324 (12%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVP-VLQPPLPLEMPPPPPPPPESP-------------- 722
+ Q S + P TP QS P +L PP + PPPPPPPP +P
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735
Query: 723 --PPPPPPPPPAEDGEIQEVEMEDEGSEEPPAP---GTEEDTPLKPSAQTTVVTSQSSVD 777
P PPPP + ++Q + + PP P P KP TS +V
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA 795
Query: 778 STISSSSSTKGIK-----RKATEISTAVVQRSATIGSSPV-------LYSQSAIATGHQA 825
++ ++ +K + + S PV S A
Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL 855
Query: 826 AGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTA 885
+ + + I Q P P A + + A A + S+P V +
Sbjct: 856 SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP--VPS 913
Query: 886 PSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPS 945
P P P ++++ PPPPP P P PPPP P P K G K K SKT P
Sbjct: 914 PDFPPPP-----PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK-KTSKTSSPG 967
Query: 946 LVKKWQSIQRELDEEDNSSSSEED 969
K + QR + +S + +
Sbjct: 968 GKKPPPTPQRNSSIKSSSGAEHPE 991
Score = 72.0 bits (175), Expect = 3e-12
Identities = 78/336 (23%), Positives = 121/336 (36%), Gaps = 46/336 (13%)
Query: 618 QSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESF 677
+SG S P+ + +Q+ +T ++ ++ S +E+ + G+ +ES
Sbjct: 535 KSGSSSSSIPESQSNHS-NQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKR--GTQLEESS 591
Query: 678 SGQVSS-----SSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPA 732
++ S +SL+P + + QP PL PPPPPPPP PPPPPPPP P+
Sbjct: 592 KARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPS 651
Query: 733 EDG-----------------EIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSS 775
+ +Q +PP P + +KP Q V +
Sbjct: 652 QSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP--QILVPPNGVV 709
Query: 776 VDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGI 835
T G + A ++ + S P + HQ I A
Sbjct: 710 PPPPPPPPPPTPG-------SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPT 762
Query: 836 GHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARG 895
P+ P +++ + AP + A P + P + +
Sbjct: 763 PPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP-----PTPTPPVPPAKKQP 817
Query: 896 AVPTATIIEPPPPPPPPPPPPPPAPKM------PPP 925
A P A+ I P PP PP P PPP PK PPP
Sbjct: 818 AFP-ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPP 852
Score = 50.4 bits (119), Expect = 8e-06
Identities = 34/98 (34%), Positives = 40/98 (40%), Gaps = 29/98 (29%)
Query: 698 SNVPVLQPPLPLEMPPPP------PPPPESP-PPPPPPPPP---------AEDGEIQEVE 741
S++PV P P PPPP PPPP SP P PPPPPPP G+
Sbjct: 907 SSIPVPSPDFP---PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT 963
Query: 742 MEDEGSEEPPAP----------GTEEDTPLKPSAQTTV 769
G + PP P G E P +PS + V
Sbjct: 964 SSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLV 1001
Score = 48.9 bits (115), Expect = 2e-05
Identities = 17/26 (65%), Positives = 20/26 (76%)
Query: 903 IEPPPPPPPPPPPPPPAPKMPPPEKT 928
+ PPPPPPPPPPPPPP P P P ++
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQS 653
Score = 48.1 bits (113), Expect = 4e-05
Identities = 17/27 (62%), Positives = 18/27 (66%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKTKKG 931
PPPPPPPPPPPPPP P +P G
Sbjct: 632 PPPPPPPPPPPPPPPPPLPSQSAPSAG 658
Score = 47.0 bits (110), Expect = 9e-05
Identities = 17/29 (58%), Positives = 20/29 (68%)
Query: 898 PTATIIEPPPPPPPPPPPPPPAPKMPPPE 926
P+ + PPPPPPPPPPPPPP P P +
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQ 652
Score = 45.8 bits (107), Expect = 2e-04
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 890 PVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVK 948
P+ + + T P PP PPPPPPPP P PPP A + + P VK
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Score = 41.2 bits (95), Expect = 0.005
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 898 PTATIIEP----PPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSI 953
P I+ P P PP PPPPPPP P PPP ++ S + K+ +I
Sbjct: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670
Query: 954 QRELDEEDNSSS 965
R + +S +
Sbjct: 671 TRLQNASQHSGA 682
Score = 35.0 bits (79), Expect = 0.36
Identities = 43/193 (22%), Positives = 64/193 (33%), Gaps = 18/193 (9%)
Query: 18 SPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQE 77
S P P P P P P P +PSQ APSA + V + + Q
Sbjct: 622 SQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTIT------RLQN 675
Query: 78 AVQEVPRVVQNPPKPVM---TTRPTAVKATGGLCLLGAYADSDDDDNDVSEKL-----AQ 129
A Q + + P PVM + +P + G+ +L A
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735
Query: 130 SKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRP---EPKEAATSTL 186
S + + ++ A P P P+ A PP PP+P P +T T+
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQV-APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTV 794
Query: 187 SSSTSNGTDSTQT 199
+ + T T
Sbjct: 795 APVVTQAAPPTPT 807
Score = 33.5 bits (75), Expect = 1.0
Identities = 35/172 (20%), Positives = 60/172 (34%), Gaps = 32/172 (18%)
Query: 5 SRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAA 64
+ P P ++ P S P P+ P S P P+P A TA+
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS 947
Query: 65 AASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVS 124
D S S ++ + P + PP P R +++K++ G
Sbjct: 948 PTPDKSGSPGKKTSKTSSPGGKKPPPTP---QRNSSIKSSSG------------------ 986
Query: 125 EKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRP 176
A+ E + +DS ++ F ++ + + P PP PP+P
Sbjct: 987 ---AEHPEP---KRPSVDSLVSKFTPPAESGSPSKETLP-----PPAAPPKP 1027
Score = 30.8 bits (68), Expect = 6.8
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 156 TAPQPAAPVGASAPPPTPPRPEP 178
TA QP+ P+ PPP PP P P
Sbjct: 620 TASQPSPPLPPPPPPPPPPPPPP 642
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 69.7 bits (169), Expect = 1e-11
Identities = 138/617 (22%), Positives = 214/617 (34%), Gaps = 128/617 (20%)
Query: 349 EEPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELE 408
EEPV V +S V T +V P + + S D + +SEEE Q EL+
Sbjct: 462 EEPVVAV--SSPAVPPPTKVVAPPSSSDSSSDSSSDSDS----STDDSEEERAQRLAELQ 515
Query: 409 LVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWK-MFVRATSPES 467
L+ +L AL SQP ++ K+ K K R E
Sbjct: 516 EQLKAVHEQLAAL----------------SQPQQNKPKKKEKDKKEKKKEKHKRKEEVEE 559
Query: 468 TSRSSSKTG--RDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQD 525
+S +K + T +N + E S K ES E+ K + EE++
Sbjct: 560 NKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS-KPPPTYESEEEDKCKPM-SYEEKRQ 617
Query: 526 LKFQIGELANTLTSKFEFLGINRQSI---SNFHVLLLQTET-RIADWRE-GALNGNYLKR 580
L I +L + + +R+ SN + + ET + + RE + L++
Sbjct: 618 LSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRK 677
Query: 581 KLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQE 640
K + AE++ ++ KG+S S ES+ E S +++
Sbjct: 678 KRKPQAEKVDVIAGSSKMKGFS----------------SSESE-----SSSESSSSDSED 716
Query: 641 NRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNV 700
+ E K K G + + Q+
Sbjct: 717 SETEMAPKSKKKGHPGREQKKHHHHHHQQ-------------------------MQQAPA 751
Query: 701 PV-LQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGS--------EEPP 751
PV QPP P + PPPPPPP + PPPPPPPP+ + EP
Sbjct: 752 PVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQ 811
Query: 752 APGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSP 811
PG+ D P+ Q + Q + + + E ST + S P
Sbjct: 812 LPGSVFD-PIGHFTQPILHLPQPELPPHLP----------QPPEHSTPPHLNQHAVVSPP 860
Query: 812 VLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAI 871
L++ A Q + N+A + + P PA + Q +A P +
Sbjct: 861 ALHN----ALPQQPSRPSNRAAALPPK--PARPPAVSPALTQTPLLPQP---PMAQPPQV 911
Query: 872 MSYAE-------CSVPIGVTAPSLQPVQ-ARGAVPTATIIEPPPPPPPP----------- 912
+ E S+ + + LQ VQ +P+ + PPPP PP
Sbjct: 912 LLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQ 971
Query: 913 --PPPPPPAPKMPPPEK 927
PPPPPP PPP++
Sbjct: 972 QQPPPPPPPQPQPPPQQ 988
Score = 53.1 bits (126), Expect = 1e-06
Identities = 82/378 (21%), Positives = 131/378 (34%), Gaps = 62/378 (16%)
Query: 676 SFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPL-------------EMPPPPPPPPESP 722
S Q+ L + P LL S QPP PL + PPPPPPP P
Sbjct: 925 SMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP 984
Query: 723 PPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISS 782
PP PP +Q ++ + PP G + P P Q + I
Sbjct: 985 PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQG--QQPPHPPPGQQPPPPQPAKPQQVIQH 1042
Query: 783 SSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPV 842
S + K+ ST ++ + SP++ + +Q + HQ+ P
Sbjct: 1043 HHSPR--HHKSDPYSTGHLREA----PSPLMIHSPQM----------SQFQSLTHQSPPQ 1086
Query: 843 SLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQP--------VQAR 894
+Q L + I S S P +PSL+P ++A
Sbjct: 1087 QNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPF---SPSLRPEPPKHPESIKAP 1143
Query: 895 GAVPT----------ATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMP 944
+P +I PP PPP P + P+ +KD K+
Sbjct: 1144 VHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWA 1203
Query: 945 SLVKKW--------QSIQRELDEEDNSSSSEEDREST--AQKRIEEWKQQQLVSGMAERN 994
SLV+K +S ++ ++ +E+RE AQ E ++++L
Sbjct: 1204 SLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSR 1263
Query: 995 ANFEALPEDWRARLKRRK 1012
+ +AL + RA + R+
Sbjct: 1264 EDEDALEQARRAHEEARR 1281
Score = 45.4 bits (106), Expect = 3e-04
Identities = 30/105 (28%), Positives = 44/105 (41%)
Query: 625 EFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSS 684
E P E E QA+ T K T N+T++S + + ++
Sbjct: 163 ELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP 222
Query: 685 SLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPP 729
P ++Q+ V + PP PL+ PPP PP P+ PP P P P
Sbjct: 223 HPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQP 267
Score = 45.4 bits (106), Expect = 3e-04
Identities = 24/51 (47%), Positives = 26/51 (50%), Gaps = 11/51 (21%)
Query: 897 VPTATIIEPPPPPPPPPPPPPPAPK-----------MPPPEKTKKGRKDKA 936
VP + PPP PP P PPP PAP+ P P KTKKG K KA
Sbjct: 242 VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKA 292
Score = 42.7 bits (99), Expect = 0.002
Identities = 24/55 (43%), Positives = 27/55 (49%), Gaps = 8/55 (14%)
Query: 889 QPVQARGAVPTATIIEPPPPPPPPPPPPPP----APKMPPPEKTKKGRKDKAKKS 939
Q QA VP +PPPPP PPPPPPP P PPP + + A KS
Sbjct: 745 QMQQAPAPVPQ----QPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKS 795
Score = 34.3 bits (77), Expect = 0.61
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 701 PVLQPPLPLEMPPP---PPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEE 757
P + P L ++ P PP P ++PPP PP P P Q V+ P P +
Sbjct: 226 PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQP-VKT 284
Query: 758 DTPLKPSAQTTVVTS 772
+K A TT T+
Sbjct: 285 KKGVKRKADTTTPTT 299
Score = 31.2 bits (69), Expect = 5.2
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 5/100 (5%)
Query: 698 SNVP-VLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEM---EDEGSEEPPAP 753
S VP Q P + P P PP P P P D +Q M + + PP
Sbjct: 194 STVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPV 253
Query: 754 GTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKA 793
+ P P+ Q V + + +T + KG+KRKA
Sbjct: 254 PPQPQPPPAPAPQ-PVQSHPPIIAATPQPVKTKKGVKRKA 292
Score = 31.2 bits (69), Expect = 5.2
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 921 KMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSS--SSEEDRE 971
K PPP+KTKK + SK K P+ +K E +EED S EE R+
Sbjct: 566 KEPPPKKTKKNNSSNSNVSK-KEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQ 617
Score = 30.8 bits (68), Expect = 6.8
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 686 LMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPP---ESPPP---PPPPPPPAEDGEIQE 739
L+ TP T++ PP+P + PPP P P +S PP P P + G ++
Sbjct: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
Query: 740 VEMEDEGSEEPPAPGTEEDTPLKPSAQTT 768
+ + +P E L P +TT
Sbjct: 292 ADTTTPTTIDP----IHEPPSLPPEPKTT 316
Score = 30.4 bits (67), Expect = 8.8
Identities = 19/83 (22%), Positives = 29/83 (34%), Gaps = 3/83 (3%)
Query: 13 PILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPS 72
P++ + PP P + P P+P+P P + A P Q P T V
Sbjct: 237 PVMTVVPPQPLQTPPPVPPQPQP---PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
Query: 73 EDEQEAVQEVPRVVQNPPKPVMT 95
+ + PP+P T
Sbjct: 294 TTTPTTIDPIHEPPSLPPEPKTT 316
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 68.9 bits (167), Expect = 2e-11
Identities = 102/484 (21%), Positives = 174/484 (35%), Gaps = 43/484 (8%)
Query: 466 ESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKV-QTTPKVEEEQ 524
E S S+ T E E E + D++SD E E E + + + K E +
Sbjct: 1035 EDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDS 1094
Query: 525 DLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQD 584
D + E + +TSK E + S S+ ++ ++ E + R+ ++
Sbjct: 1095 DEE----ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEE-----EVVAREEEE 1145
Query: 585 AAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDE 644
E+ + + +++D + + E E+ A E R
Sbjct: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205
Query: 645 TLAKQTLKDKTGTDSNSTESSE----TSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNV 700
L + L ++S E E + G++ + PL+P
Sbjct: 1206 MLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLE 1265
Query: 701 PVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTP 760
+PP+ L +P PP PP PP PP PPP E + + PP P E+ P
Sbjct: 1266 VEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSV-------PPEPLAEDHPP 1318
Query: 761 LKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLY--SQSA 818
P ++ SQS+ + +T G + + S+ + S + SP Y +
Sbjct: 1319 HTPGLCGSLAKSQST-----ETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPS 1373
Query: 819 IATGHQAAGIGNQ---ATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYA 875
+++G G + P+ LP + R G A+P ++
Sbjct: 1374 LSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRR-----DERSGPLASPVLL--- 1425
Query: 876 ECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDK 935
E +P+ + P P+ A+P + P P PP P P PPP K K GR +
Sbjct: 1426 ETGLPLPLPLPLPLPL----ALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRR 1481
Query: 936 AKKS 939
+ S
Sbjct: 1482 SPPS 1485
Score = 60.8 bits (146), Expect = 6e-09
Identities = 73/286 (25%), Positives = 100/286 (34%), Gaps = 75/286 (26%)
Query: 706 PLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEE---PPAPGTEEDTPLK 762
P P +PP P E P PP PPPP + ME G P P TP
Sbjct: 432 PAPPPLPPAEPLAKEKPGTPPGPPPPDTNS------MELGGRPTFGWSPEPCDSPGTPTL 485
Query: 763 PSAQTTVVTSQSSVDSTIS---SSSSTKGIKRKATEISTAVVQRSATIGSS--------- 810
S+ S+DS I TK + + + T + + I SS
Sbjct: 486 ESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAP 545
Query: 811 -----------PVLYSQSAIATGHQAA----------------GIGNQA---------TG 834
P S +TG + G+G + G
Sbjct: 546 FGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAG 605
Query: 835 IGHQTIPVSLPAAG----------MGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVT 884
+ QT V+L G G Q+ G ++ + + +AP ++ A+C P+ VT
Sbjct: 606 LLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP--ITSADCPKPMVVT 663
Query: 885 APSLQPVQARGAVPTATIIEPPP-----PPPPPPPPPPPAPKMPPP 925
P V A + + PPP PPPPPPPPP P MPPP
Sbjct: 664 -PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPP 708
Score = 54.3 bits (129), Expect = 6e-07
Identities = 79/289 (27%), Positives = 105/289 (36%), Gaps = 68/289 (23%)
Query: 703 LQPPLPLEMPP-PPPPPPE------SPPPPPPPP-----PPAEDGEIQEVEMEDEGSEEP 750
LQPPLP PP PP PPPE S P PP P PP G + P
Sbjct: 1278 LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVP 1337
Query: 751 PAPGTEEDTPLKPSAQTTVVTSQSSVDSTI-----SSSSSTKGIKRKATEISTAVVQRSA 805
PG E PL + ++S S S S S+ G+ R + S
Sbjct: 1338 ATPGGE--PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSE 1395
Query: 806 TIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQT-----------IPVSLPAAGMGHQAR 854
S P+L + TG + G A+ + +T +P++LPA + QAR
Sbjct: 1396 P--SGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAV-LRAQAR 1452
Query: 855 GMSLQSNYL--GLAAAPAIM----SYAECSVP--IGVTAPSLQPVQARGAVPTATIIEP- 905
+ L LA+ P M S P + + P ++P A A+ ++ P
Sbjct: 1453 APTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRP-PAGAALGRELLLLPG 1511
Query: 906 -------------------------PPPPPPPPPPPPPAPKMPPPEKTK 929
P PPPP PP PPP P PP E TK
Sbjct: 1512 QPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTK 1560
Score = 48.5 bits (114), Expect = 3e-05
Identities = 47/163 (28%), Positives = 63/163 (38%), Gaps = 12/163 (7%)
Query: 694 TLLQSNVPVLQPPLPLEMPPPPPPPPESP----PPPPPPPPPAEDGEIQEVEMEDEGSEE 749
++L +P+ PP +PPPPPPPP P PPP PPPPP V +
Sbjct: 673 SVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732
Query: 750 PP-APGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSAT-I 807
PP P PL P Q + + G + ++ T V+ R T
Sbjct: 733 PPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQ---WGGMPMSFQMQTQVLSRLMTGQ 789
Query: 808 GSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMG 850
G+ P +A A AA G Q + P SL +G G
Sbjct: 790 GACPYPPFMAAAAA---AASAGLQFVNLPPYRGPFSLSNSGPG 829
Score = 48.5 bits (114), Expect = 3e-05
Identities = 36/116 (31%), Positives = 50/116 (43%), Gaps = 8/116 (6%)
Query: 651 LKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLM----PLTPFWTLLQSNVPVLQPP 706
+K K G S S + G L + + L+ P TP + V
Sbjct: 1472 MKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDF 1531
Query: 707 LPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEE--PPAP-GTEEDT 759
+P PPPP P PPP PPPPPP E ++ E++++ E PP P G +E T
Sbjct: 1532 RNAGIPAPPPPLPPQPPP-PPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVT 1586
Score = 45.1 bits (105), Expect = 3e-04
Identities = 62/245 (25%), Positives = 81/245 (33%), Gaps = 35/245 (14%)
Query: 682 SSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVE 741
SSS L PL PF T Q P PP P S P P D + E
Sbjct: 536 SSSQLSPLAPFGTNSQPG---------FRGPTPPSSRPSSTGLEDISPTPLPDSDEDEEL 586
Query: 742 MEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVV 801
G PP PG + L +QT V D T +S +G + ++ +
Sbjct: 587 DLGLGPRPPPEPGPPDPAGLL--SQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDD 644
Query: 802 QRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSN 861
+ + +S + G A A + T+P+ P G
Sbjct: 645 EMPSAPITSADCPKPMVVTPGAAAVA----APSVLAPTLPLP-PPPGFPPLPPPPPPPPP 699
Query: 862 YLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPP--PPPPPA 919
G P P+ P P A P T+ PPPP P PP PPPP
Sbjct: 700 QPGFPMPP----------PLPPPPPPPPP-----AHPAVTV--PPPPLPAPPGVPPPPIL 742
Query: 920 PKMPP 924
P +PP
Sbjct: 743 PPLPP 747
Score = 43.9 bits (102), Expect = 8e-04
Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 9/112 (8%)
Query: 631 EEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLT 690
E+ +E Q D ++ + T ++ + + G+ + S + L P
Sbjct: 626 EKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPP 685
Query: 691 PFWTLLQSNVPVLQPPLP-LEMPPPPPPPPESPPPP------PPPPPPAEDG 735
F L P PP P MPPP PPPP PPP PPPP PA G
Sbjct: 686 GFPPLPPPPPP--PPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG 735
Score = 37.4 bits (85), Expect = 0.072
Identities = 51/190 (26%), Positives = 67/190 (35%), Gaps = 54/190 (28%)
Query: 16 QLSPPGPRG--STPG-RDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPS 72
QLSP P G S PG R P P P + P ST P P D
Sbjct: 539 QLSPLAPFGTNSQPGFRGPTP-PSSRPSSTGLEDISPTP--------------LPDSDED 583
Query: 73 EDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKE 132
E+ + P PP P TA A L L+G D SEK+ + ++
Sbjct: 584 EELDLGLGPRPPPEPGPPDPAGLLSQTAEVA---LDLVG-------DRTPTSEKMDEGQQ 633
Query: 133 TNGNQSTDIDSTLANFLAEIDAITAPQP------AAPVGASA------------------ 168
++G D + + A I + P+P AA V A +
Sbjct: 634 SSGEDMEISDDEMPS--APITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLP 691
Query: 169 PPPTPPRPEP 178
PPP PP P+P
Sbjct: 692 PPPPPPPPQP 701
Score = 32.7 bits (73), Expect = 1.8
Identities = 43/177 (24%), Positives = 77/177 (43%), Gaps = 15/177 (8%)
Query: 336 EEEERWRRKVICKEEPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQ---EDLCSVVQ 392
EE ER R + + + P K V +P E+ ED + E+ S +
Sbjct: 992 EESERERDRDMA-DTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEE 1050
Query: 393 SGESEEEEEQDTLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSK 452
E+EEEEE++ + + +R ++E ++ D ++S +S + + D +
Sbjct: 1051 EEEAEEEEEEEDDDDDDSDDRDESEN---DDEDTALSEASEKDE----GDSDEEETVSIV 1103
Query: 453 RGKWKMFVRATSPESTS-RSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEES 508
K + + S ES+ SSS++ + E+ E + E E E ++EM EES
Sbjct: 1104 TSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEE---EEEEEEMVAEES 1157
Score = 32.7 bits (73), Expect = 1.8
Identities = 11/17 (64%), Positives = 12/17 (70%)
Query: 904 EPPPPPPPPPPPPPPAP 920
+PPPPPPPPP P P
Sbjct: 1546 QPPPPPPPPPVEPTKLP 1562
Score = 31.6 bits (70), Expect = 4.0
Identities = 41/158 (25%), Positives = 56/158 (35%), Gaps = 25/158 (15%)
Query: 36 DTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMT 95
D E D A + AP AV + ++ E E A +E P ++ PP PV
Sbjct: 1165 DFEQDGEEAALAPGAP--------AVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGV 1216
Query: 96 TRPTAVKATG---GLCLLGAYADSDDDD-NDVSEKLAQSKETNGNQSTDIDSTLANFLAE 151
P + GL GA S + +V + S E +++ L
Sbjct: 1217 EEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMML-- 1274
Query: 152 IDAITAPQPAAPVGASAPPPTPPRP--EPKEAATSTLS 187
P P P PPP PPRP P E T+ S
Sbjct: 1275 ------PLPLQP---PLPPPRPPRPPSPPPEPETTDAS 1303
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 66.6 bits (161), Expect = 1e-10
Identities = 126/590 (21%), Positives = 223/590 (37%), Gaps = 108/590 (18%)
Query: 347 CKEEPVSEVKETSTT--VEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDT 404
C EP+ + + ++E+ V+P+E M E +E++ + ++ E+EE EE+D
Sbjct: 1187 CVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQA--EAEEAEEGEEEDA 1244
Query: 405 LELELVLERKKAELRALEEGDGSVSGSSPRSDISQP-ASQDGMRRLMSKRGKWKMFVRAT 463
+E+ A D S +SP ++ +P ++ + +S+ + +
Sbjct: 1245 AS---------SEVPAASPADSS---NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292
Query: 464 SPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEE 523
E +T +N + E+ ++ S K+ E+EE P + V+ P V+E
Sbjct: 1293 LEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE--STKKKELEEQPTREDVKEEPGVQES 1350
Query: 524 QDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQ 583
FL N Q ++ +I D E L
Sbjct: 1351 -------------------FLDANMQ----------KSREKIKDKEETEL---------- 1371
Query: 584 DAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRD 643
D+ E+ ++ + + + D DH E+ ++ E + +EEEE ++ + +
Sbjct: 1372 DSEEEQPSHDTSVVSEQMAGSED-DH-------EEDSHTKEELIELKEEEEIPHSELDLE 1423
Query: 644 ETLAKQTLKDKTGTDSNSTESSETSTGSLCK--ESFSGQVSSSSLMPLTPFWTLLQSNVP 701
A Q+L + ++ T + C+ +S++ Q M + + N P
Sbjct: 1424 TVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYT-QADEDPQMSMVEDCHASEHNSP 1482
Query: 702 VLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPL 761
+ P +S P PA + ++ E +GS P+ E +P+
Sbjct: 1483 ISSVQ---------SHPSQSVRSVSSPNVPALESGYTQISPE-QGSLSAPSMQNMETSPM 1532
Query: 762 KPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIAT 821
+ SQ VDS S S + TE +T+G S S S +
Sbjct: 1533 M-DVPSVSDHSQQVVDSGFSDLGSIES----TTENYENPSSYDSTMGGSICGNSSSQSSC 1587
Query: 822 GHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPI 881
+ G + ++ + + V+ A MG M Q + + AA +I S C V
Sbjct: 1588 SY---GGLSSSSSLTQSSCVVTQQMASMGSSCSMM--QQSSVQPAANCSIKSPQSCVVE- 1641
Query: 882 GVTAPSLQPVQARGAVPTATIIEPPPPPP----PPPPPPPPAPKMPPPEK 927
PS Q Q PPPPPP PPPP P PAP+ PPP++
Sbjct: 1642 --RPPSNQQQQ------------PPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
Score = 53.5 bits (127), Expect = 1e-06
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 16/141 (11%)
Query: 661 STESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVP-----VLQPPLPLEMPPPP 715
S+ SS T + + + + SS S+M + ++ V++ P + PP
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPP 1652
Query: 716 PPPPESPPPPPP-------PPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTT 768
PPPP+ P PPPP PPPP + + Q + + + PP P ++ PL +
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQP---QPQPQQPPPPPPPQQQPPLSQCSMNN 1709
Query: 769 VVTSQSSVDSTISSSSSTKGI 789
T + I S ST I
Sbjct: 1710 SFTPAPMI-MEIPESGSTGNI 1729
Score = 30.4 bits (67), Expect = 8.8
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 17/170 (10%)
Query: 262 SSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGV 321
S VP A + N+ ++ K V + P +++ + + E + Q L E E++
Sbjct: 1247 SEVPAASPADSSNSP-ETETKEPEVEEEEEKPRVSEEQRQSEEEQ--QELEEPEPEEEED 1303
Query: 322 AASLLAP-------------LLPEGIKEEEERWRRKVICKEEPVSEVKETSTTVEEATTI 368
AA+ A L KE EE+ R+ + +E V E + + I
Sbjct: 1304 AAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Query: 369 VKPQEIMLDNIED-PSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAE 417
+E LD+ E+ PS + Q SE++ E+D+ E ++E K+ E
Sbjct: 1364 KDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE 1413
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 66.6 bits (161), Expect = 1e-10
Identities = 126/590 (21%), Positives = 223/590 (37%), Gaps = 108/590 (18%)
Query: 347 CKEEPVSEVKETSTT--VEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDT 404
C EP+ + + ++E+ V+P+E M E +E++ + ++ E+EE EE+D
Sbjct: 1187 CVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQA--EAEEAEEGEEEDA 1244
Query: 405 LELELVLERKKAELRALEEGDGSVSGSSPRSDISQP-ASQDGMRRLMSKRGKWKMFVRAT 463
+E+ A D S +SP ++ +P ++ + +S+ + +
Sbjct: 1245 AS---------SEVPAASPADSS---NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292
Query: 464 SPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEE 523
E +T +N + E+ ++ S K+ E+EE P + V+ P V+E
Sbjct: 1293 LEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE--STKKKELEEQPTREDVKEEPGVQES 1350
Query: 524 QDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQ 583
FL N Q ++ +I D E L
Sbjct: 1351 -------------------FLDANMQ----------KSREKIKDKEETEL---------- 1371
Query: 584 DAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRD 643
D+ E+ ++ + + + D DH E+ ++ E + +EEEE ++ + +
Sbjct: 1372 DSEEEQPSHDTSVVSEQMAGSED-DH-------EEDSHTKEELIELKEEEEIPHSELDLE 1423
Query: 644 ETLAKQTLKDKTGTDSNSTESSETSTGSLCK--ESFSGQVSSSSLMPLTPFWTLLQSNVP 701
A Q+L + ++ T + C+ +S++ Q M + + N P
Sbjct: 1424 TVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYT-QADEDPQMSMVEDCHASEHNSP 1482
Query: 702 VLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPL 761
+ P +S P PA + ++ E +GS P+ E +P+
Sbjct: 1483 ISSVQ---------SHPSQSVRSVSSPNVPALESGYTQISPE-QGSLSAPSMQNMETSPM 1532
Query: 762 KPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIAT 821
+ SQ VDS S S + TE +T+G S S S +
Sbjct: 1533 M-DVPSVSDHSQQVVDSGFSDLGSIES----TTENYENPSSYDSTMGGSICGNSSSQSSC 1587
Query: 822 GHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPI 881
+ G + ++ + + V+ A MG M Q + + AA +I S C V
Sbjct: 1588 SY---GGLSSSSSLTQSSCVVTQQMASMGSSCSMM--QQSSVQPAANCSIKSPQSCVVE- 1641
Query: 882 GVTAPSLQPVQARGAVPTATIIEPPPPPP----PPPPPPPPAPKMPPPEK 927
PS Q Q PPPPPP PPPP P PAP+ PPP++
Sbjct: 1642 --RPPSNQQQQ------------PPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
Score = 53.5 bits (127), Expect = 1e-06
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 16/141 (11%)
Query: 661 STESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVP-----VLQPPLPLEMPPPP 715
S+ SS T + + + + SS S+M + ++ V++ P + PP
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPP 1652
Query: 716 PPPPESPPPPPP-------PPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTT 768
PPPP+ P PPPP PPPP + + Q + + + PP P ++ PL +
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQP---QPQPQQPPPPPPPQQQPPLSQCSMNN 1709
Query: 769 VVTSQSSVDSTISSSSSTKGI 789
T + I S ST I
Sbjct: 1710 SFTPAPMI-MEIPESGSTGNI 1729
Score = 30.4 bits (67), Expect = 8.8
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 17/170 (10%)
Query: 262 SSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGV 321
S VP A + N+ ++ K V + P +++ + + E + Q L E E++
Sbjct: 1247 SEVPAASPADSSNSP-ETETKEPEVEEEEEKPRVSEEQRQSEEEQ--QELEEPEPEEEED 1303
Query: 322 AASLLAP-------------LLPEGIKEEEERWRRKVICKEEPVSEVKETSTTVEEATTI 368
AA+ A L KE EE+ R+ + +E V E + + I
Sbjct: 1304 AAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Query: 369 VKPQEIMLDNIED-PSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAE 417
+E LD+ E+ PS + Q SE++ E+D+ E ++E K+ E
Sbjct: 1364 KDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE 1413
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 66.6 bits (161), Expect = 1e-10
Identities = 126/590 (21%), Positives = 223/590 (37%), Gaps = 108/590 (18%)
Query: 347 CKEEPVSEVKETSTT--VEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDT 404
C EP+ + + ++E+ V+P+E M E +E++ + ++ E+EE EE+D
Sbjct: 1187 CVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQA--EAEEAEEGEEEDA 1244
Query: 405 LELELVLERKKAELRALEEGDGSVSGSSPRSDISQP-ASQDGMRRLMSKRGKWKMFVRAT 463
+E+ A D S +SP ++ +P ++ + +S+ + +
Sbjct: 1245 AS---------SEVPAASPADSS---NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292
Query: 464 SPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEE 523
E +T +N + E+ ++ S K+ E+EE P + V+ P V+E
Sbjct: 1293 LEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE--STKKKELEEQPTREDVKEEPGVQES 1350
Query: 524 QDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQ 583
FL N Q ++ +I D E L
Sbjct: 1351 -------------------FLDANMQ----------KSREKIKDKEETEL---------- 1371
Query: 584 DAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRD 643
D+ E+ ++ + + + D DH E+ ++ E + +EEEE ++ + +
Sbjct: 1372 DSEEEQPSHDTSVVSEQMAGSED-DH-------EEDSHTKEELIELKEEEEIPHSELDLE 1423
Query: 644 ETLAKQTLKDKTGTDSNSTESSETSTGSLCK--ESFSGQVSSSSLMPLTPFWTLLQSNVP 701
A Q+L + ++ T + C+ +S++ Q M + + N P
Sbjct: 1424 TVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYT-QADEDPQMSMVEDCHASEHNSP 1482
Query: 702 VLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPL 761
+ P +S P PA + ++ E +GS P+ E +P+
Sbjct: 1483 ISSVQ---------SHPSQSVRSVSSPNVPALESGYTQISPE-QGSLSAPSMQNMETSPM 1532
Query: 762 KPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIAT 821
+ SQ VDS S S + TE +T+G S S S +
Sbjct: 1533 M-DVPSVSDHSQQVVDSGFSDLGSIES----TTENYENPSSYDSTMGGSICGNSSSQSSC 1587
Query: 822 GHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPI 881
+ G + ++ + + V+ A MG M Q + + AA +I S C V
Sbjct: 1588 SY---GGLSSSSSLTQSSCVVTQQMASMGSSCSMM--QQSSVQPAANCSIKSPQSCVVE- 1641
Query: 882 GVTAPSLQPVQARGAVPTATIIEPPPPPP----PPPPPPPPAPKMPPPEK 927
PS Q Q PPPPPP PPPP P PAP+ PPP++
Sbjct: 1642 --RPPSNQQQQ------------PPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
Score = 53.5 bits (127), Expect = 1e-06
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 16/141 (11%)
Query: 661 STESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVP-----VLQPPLPLEMPPPP 715
S+ SS T + + + + SS S+M + ++ V++ P + PP
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPP 1652
Query: 716 PPPPESPPPPPP-------PPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTT 768
PPPP+ P PPPP PPPP + + Q + + + PP P ++ PL +
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQP---QPQPQQPPPPPPPQQQPPLSQCSMNN 1709
Query: 769 VVTSQSSVDSTISSSSSTKGI 789
T + I S ST I
Sbjct: 1710 SFTPAPMI-MEIPESGSTGNI 1729
Score = 30.4 bits (67), Expect = 8.8
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 17/170 (10%)
Query: 262 SSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGV 321
S VP A + N+ ++ K V + P +++ + + E + Q L E E++
Sbjct: 1247 SEVPAASPADSSNSP-ETETKEPEVEEEEEKPRVSEEQRQSEEEQ--QELEEPEPEEEED 1303
Query: 322 AASLLAP-------------LLPEGIKEEEERWRRKVICKEEPVSEVKETSTTVEEATTI 368
AA+ A L KE EE+ R+ + +E V E + + I
Sbjct: 1304 AAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Query: 369 VKPQEIMLDNIED-PSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAE 417
+E LD+ E+ PS + Q SE++ E+D+ E ++E K+ E
Sbjct: 1364 KDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE 1413
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 66.2 bits (160), Expect = 1e-10
Identities = 81/341 (23%), Positives = 122/341 (35%), Gaps = 58/341 (17%)
Query: 701 PVLQPPLPLEMPPPP---PPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEE 757
P L P P PPPP PPPP P PPPPPPP A E E+P P T
Sbjct: 1486 PPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT-R 1544
Query: 758 DTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQS 817
L +T V ++ + + S +GI R+ E V R+ I S +
Sbjct: 1545 PLHLAKKQETAAVCGETDEE---AGESGGEGIFRERDEF----VIRAEDIPSLKL----- 1592
Query: 818 AIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLG------------- 864
A+ TG + I + + P + R SNYLG
Sbjct: 1593 ALQTGREPPPIWRVQKALLQKFTP------EIKDGQRQFCATSNYLGYFGDAKNRYQRLY 1646
Query: 865 -----------LAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPP 913
A + VP+ + + PV A G+ PPP P P
Sbjct: 1647 VKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGS-------SAPPPKAPAP 1699
Query: 914 PPPPPAPKMPPPEKTKKGRKDKA--KKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRE 971
PP P P+ EK + + A + + PSL++ +++E ++E + R
Sbjct: 1700 PPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLR---PVEKEKEKEKVTRGERPLRG 1756
Query: 972 STAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRRK 1012
A + ++ L +G + +A P +A +K
Sbjct: 1757 ERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKK 1797
Score = 62.0 bits (149), Expect = 3e-09
Identities = 90/356 (25%), Positives = 126/356 (35%), Gaps = 74/356 (20%)
Query: 655 TGTDSNSTESSETSTGSLCK----ESFSGQVSSSSLMPLTPFWTLLQSNVPVLQ----PP 706
+GTD NS +SS T K E ++ S + F + + P+ Q PP
Sbjct: 1247 SGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPP 1306
Query: 707 L--PLEMPPP------PPPPPESPPPPPPPPPPAED--GEIQEVEMEDEGSEEPPAPGTE 756
L P +PP P PP +P P PPP A G ++ E E G P+P
Sbjct: 1307 LSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLG-CPSPCKR 1365
Query: 757 EDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQ 816
D LK + +T S DS K ++ ++ + + P+
Sbjct: 1366 LDEELKRNLETLPSFSSDEEDSVA-----------KNRDLQESISSAISALDDPPL---- 1410
Query: 817 SAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAE 876
AG + +T G P PAA + L S P ++ E
Sbjct: 1411 ---------AGPKDTSTPDG----PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLE--E 1455
Query: 877 CSVPIGVTAPSLQPVQARGAVPTATIIEPPPP--------PPPPPPPPPPAPKMP----- 923
P AP+ QP P + PPP PPPPP PPPP P MP
Sbjct: 1456 KPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP 1515
Query: 924 ----------PPEKTKKGRKDKAKKSKTKMPSLVKKWQ--SIQRELDEEDNSSSSE 967
PPE+ + + T+ L KK + ++ E DEE S E
Sbjct: 1516 PPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGE 1571
Score = 53.9 bits (128), Expect = 7e-07
Identities = 89/381 (23%), Positives = 128/381 (33%), Gaps = 99/381 (25%)
Query: 690 TPFWTLLQSNVPVLQPPLPLEMPPPPPP-------------------------------P 718
TP LL++ P LPL +PPPPP
Sbjct: 777 TPHGLLLEAG----GPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGA 832
Query: 719 PESPPPPPPPPPPAE------------DGEIQEVEMEDEGSEEPPAPGTE---EDTPLKP 763
P+ PPPPPPPPPP + + E S +PP E PL P
Sbjct: 833 PQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPP 892
Query: 764 SAQTTVV---TSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSS-----PVLYS 815
+ T V S+ + S S +G K T++ + + P +
Sbjct: 893 APGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEE 952
Query: 816 Q--SAIATGHQAAGI----GNQATGIGHQTIPVSLP---------AAGMGHQARGMSLQS 860
A + AG G+ G G P + A+G G + G+ L
Sbjct: 953 MFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDP 1012
Query: 861 NYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPA- 919
N P + PS + G + + PPPPPPPPPPP PA
Sbjct: 1013 N-----KPPEL--------------PSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPAS 1053
Query: 920 -PKMPPPEKTKKGRKDKAKKSKTKMPSLVKK----WQSIQRELDEEDNSSSSEEDRESTA 974
PK K K K KT L+++ +Q+ ++ +E + E+ + A
Sbjct: 1054 EPKGGLTSPIFCSTKPK-KLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPA 1112
Query: 975 QKRIEEWKQQQLVSGMAERNA 995
R+ + LVS R A
Sbjct: 1113 DIRLNPRRLPDLVSSCRSRPA 1133
Score = 36.2 bits (82), Expect = 0.16
Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 683 SSSLMPLTPFWTLLQSNVPVLQPPL---PLEMPPPPPPPPESPPPPPPPPPPAEDGE 736
+S P TP L + P L + PL + P PPPPPPPPPPA E
Sbjct: 998 ASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASE 1054
Score = 34.7 bits (78), Expect = 0.47
Identities = 68/296 (22%), Positives = 96/296 (32%), Gaps = 95/296 (32%)
Query: 708 PLEMPPPPPPPPE--SPPPP--------------PPPPPPAEDGEIQEVEMEDEGSE--- 748
PL+ PP PP SP P PP + + + +GSE
Sbjct: 567 PLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLA 626
Query: 749 ---EPPAPGTEED-----------TPLKPSAQTTVVTSQSSVDST--ISSSSSTKGIKRK 792
PPA TE++ +P + S +V + D++ + S G
Sbjct: 627 GPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGT 686
Query: 793 ATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQAT-----GIGHQTIPVSLPAA 847
E++ QR + QS I T +A + AT G+G P
Sbjct: 687 PYELAKEDPQR---------YHLQSVIRT---SASLDEGATAALELGLGRLKEKKKGPER 734
Query: 848 GMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQP------VQARGAVPTAT 901
G G G++ + G A + P TA S QP ++A G P
Sbjct: 735 G-GETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGG--PDLP 791
Query: 902 IIEPPPP----------------------------------PPPPPPPPPPAPKMP 923
++ PPPP P PPPPPPPP P MP
Sbjct: 792 LVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847
Score = 31.6 bits (70), Expect = 4.0
Identities = 43/175 (24%), Positives = 60/175 (34%), Gaps = 14/175 (8%)
Query: 17 LSPP-GPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASD-----DS 70
L+PP P S P P +P +T AVP P PS A A+ AA + S
Sbjct: 1303 LTPPLSPPKSVPPSVPARGLQPQPPATPAVP-HPPPSGAFGLGGALEAAESEGLGLGCPS 1361
Query: 71 P----SEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLG--AYADSDDDDNDVS 124
P E+ + ++ +P + V R + + L A D
Sbjct: 1362 PCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDG 1421
Query: 125 EKLAQSKETNGNQSTD-IDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEP 178
LA + G + S +N E + P P A P P PP P P
Sbjct: 1422 PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPP 1476
Score = 31.2 bits (69), Expect = 5.2
Identities = 25/92 (27%), Positives = 32/92 (34%), Gaps = 31/92 (33%)
Query: 714 PPPPPPESPPP----------------PPPPPPPAED--------------GEIQEVEME 743
P PPPPE P PPPPPPPA G +
Sbjct: 273 PGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACS 332
Query: 744 DEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSS 775
G E P+PG E + PS T + +++
Sbjct: 333 PLGGGE-PSPGAGEPSKAGPSGATAGASGRAT 363
Score = 31.2 bits (69), Expect = 5.2
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 4/65 (6%)
Query: 9 PGRRPILQLSPP--GPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAA 66
P +P L PP P S+P P P P P + + P P P+AA AA
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSP--PPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAP 1533
Query: 67 SDDSP 71
S + P
Sbjct: 1534 SPEDP 1538
Score = 31.2 bits (69), Expect = 5.2
Identities = 17/42 (40%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 157 APQPAAPVGASAPPPTPPRPEPK-EAATSTLSSSTSNGTDST 197
A P + G+SAPPP P P PK E T S T T
Sbjct: 1680 AKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPET 1721
Score = 30.8 bits (68), Expect = 6.8
Identities = 11/18 (61%), Positives = 11/18 (61%)
Query: 714 PPPPPPESPPPPPPPPPP 731
P PP P PP PPPPP
Sbjct: 221 PAQTPPYRPGPPDPPPPP 238
Score = 30.4 bits (67), Expect = 8.8
Identities = 51/195 (26%), Positives = 66/195 (33%), Gaps = 47/195 (24%)
Query: 17 LSPPGPRGSTPG---RDPEPE----PDTEPDSTAAVPS---QPAPSAATTTTTAVTAAAA 66
+ PP G P R P P+ P P ++ P Q + T + A
Sbjct: 899 VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGA 958
Query: 67 SDD----SPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDND 122
+DD P EDE + P+ PP P A G C
Sbjct: 959 ADDYGKAGPPEDEGD-----PKAGAGPPPG-----PPAYDPYGPYC-------------- 994
Query: 123 VSEKLAQSKETNG-----NQSTDIDSTL-ANFLAEIDAITAPQPAAPVGASAPPPTP-PR 175
ET G N+ ++ ST+ A L I + P AAP PPP P P
Sbjct: 995 PGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS--GPHQAAPPPPPPPPPPPAPA 1052
Query: 176 PEPKEAATSTLSSST 190
EPK TS + ST
Sbjct: 1053 SEPKGGLTSPIFCST 1067
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 65.9 bits (159), Expect = 2e-10
Identities = 59/204 (28%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 574 NGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFY--VNEQSGESQWEFPDGEE 631
N ++L KLQD + + + + + D R Y N Q + + EE
Sbjct: 401 NISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEE 460
Query: 632 EEEESQAQENRDETLAKQ-TLKDKTGTDSNSTESSETSTGSLC--KESFSGQ-------V 681
+ E + L KQ T+K + D + ++G+L E +G
Sbjct: 461 AIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGA 520
Query: 682 SSSSLMPLTPFWTLLQSNVP--VLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQE 739
+SS +P P S+ P V P+ MPPPPPPPP PPPPPPPPPP G E
Sbjct: 521 ASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAE 580
Query: 740 V----EMEDEGSEEPPAPGTEEDT 759
+ PP PGT T
Sbjct: 581 TVPAPPLAPPLPSAPPLPGTSSPT 604
Score = 51.6 bits (122), Expect = 4e-06
Identities = 21/46 (45%), Positives = 27/46 (58%)
Query: 880 PIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPP 925
P+ ++ + + VQ P PPPPPPPPPPPPPP P +P P
Sbjct: 532 PLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGP 577
Score = 46.6 bits (109), Expect = 1e-04
Identities = 17/24 (70%), Positives = 18/24 (75%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKT 928
PPPPPPPPPPPPPP P P +T
Sbjct: 558 PPPPPPPPPPPPPPPPLPGPAAET 581
Score = 43.5 bits (101), Expect = 0.001
Identities = 19/44 (43%), Positives = 20/44 (45%)
Query: 882 GVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPP 925
G P P+ P P PP PPPPPPPP P PPP
Sbjct: 524 GPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPP 567
Score = 39.7 bits (91), Expect = 0.015
Identities = 17/35 (48%), Positives = 17/35 (48%), Gaps = 15/35 (42%)
Query: 905 PPPPPPPPPPPP---------------PPAPKMPP 924
PPPPPPPPPPPP PP P PP
Sbjct: 562 PPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPP 596
Score = 38.5 bits (88), Expect = 0.032
Identities = 16/26 (61%), Positives = 17/26 (65%), Gaps = 5/26 (19%)
Query: 905 PPPPPPPPPPPPP-----PAPKMPPP 925
PPPPPPPPP P P PAP + PP
Sbjct: 565 PPPPPPPPPLPGPAAETVPAPPLAPP 590
Score = 33.1 bits (74), Expect = 1.4
Identities = 20/67 (29%), Positives = 22/67 (32%), Gaps = 20/67 (29%)
Query: 879 VPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPP--------------------PPPP 918
V G + + V PT P PPPPPP PPPP
Sbjct: 497 VASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPP 556
Query: 919 APKMPPP 925
P PPP
Sbjct: 557 PPPPPPP 563
Score = 31.6 bits (70), Expect = 4.0
Identities = 20/55 (36%), Positives = 23/55 (41%), Gaps = 7/55 (12%)
Query: 878 SVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPP-----PPPPPAPKMP--PP 925
+V G P + P P PPPPP P P P PP AP +P PP
Sbjct: 542 TVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPP 596
Score = 30.8 bits (68), Expect = 6.8
Identities = 22/75 (29%), Positives = 28/75 (37%), Gaps = 27/75 (36%)
Query: 905 PPPPPPPPPPP--------------------PPPAPKMPPPEKTKKG-----RKDKAKKS 939
PPPPPPPPPPP PP P P + K K+
Sbjct: 563 PPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKT 622
Query: 940 KTKMPSLVKKWQSIQ 954
K +MP V W +++
Sbjct: 623 KFRMP--VFNWVALK 635
>gi|195947369 junction-mediating and regulatory protein [Homo
sapiens]
Length = 988
Score = 65.1 bits (157), Expect = 3e-10
Identities = 53/187 (28%), Positives = 79/187 (42%), Gaps = 23/187 (12%)
Query: 632 EEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTP 691
EE+ + E R + QT + ++ T ++ SL SG S +P T
Sbjct: 731 EEKTEEVGEGRVKRGPSQTTEPQSLVQLEDTSLTQLEATSL---PLSGVTSE---LPPTI 784
Query: 692 FWTLLQSNVP---VLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSE 748
LL +N+ V PLP +PP PPPPP PPPPPPPP P +D G E
Sbjct: 785 SLPLLNNNLEPCSVTINPLPSPLPPTPPPPPPPPPPPPPPPLPV---------AKDSGPE 835
Query: 749 EPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIG 808
E+D P K + + S S+ + + SS ++K + + + +R +
Sbjct: 836 T-----LEKDLPRKEGNEKRIPKSASAPSAHLFDSSQLVSARKKLRKTAEGLQRRRVSSP 890
Query: 809 SSPVLYS 815
VL S
Sbjct: 891 MDEVLAS 897
Score = 46.2 bits (108), Expect = 2e-04
Identities = 16/26 (61%), Positives = 19/26 (73%)
Query: 898 PTATIIEPPPPPPPPPPPPPPAPKMP 923
P + + P PPPPPPPPPPPP P +P
Sbjct: 802 PLPSPLPPTPPPPPPPPPPPPPPPLP 827
Score = 45.1 bits (105), Expect = 3e-04
Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 12/71 (16%)
Query: 877 CSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKG--RKD 934
CSV I L P T PPPPPPPPPPPP P K PE +K RK+
Sbjct: 796 CSVTINPLPSPLPP----------TPPPPPPPPPPPPPPPLPVAKDSGPETLEKDLPRKE 845
Query: 935 KAKKSKTKMPS 945
+K K S
Sbjct: 846 GNEKRIPKSAS 856
Score = 44.3 bits (103), Expect = 6e-04
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 878 SVPI-GVTA---PSLQ-PVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGR 932
S+P+ GVT+ P++ P+ P + I P P P PP PPPPP P PPP
Sbjct: 770 SLPLSGVTSELPPTISLPLLNNNLEPCSVTINPLPSPLPPTPPPPPPPPPPPPPPPLPVA 829
Query: 933 KDKAKKSKTK 942
KD ++ K
Sbjct: 830 KDSGPETLEK 839
Score = 43.9 bits (102), Expect = 8e-04
Identities = 24/74 (32%), Positives = 32/74 (43%)
Query: 865 LAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 924
L A +S +P ++ P L +V + P PP PPPPPPPPP P PP
Sbjct: 766 LEATSLPLSGVTSELPPTISLPLLNNNLEPCSVTINPLPSPLPPTPPPPPPPPPPPPPPP 825
Query: 925 PEKTKKGRKDKAKK 938
K + +K
Sbjct: 826 LPVAKDSGPETLEK 839
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 65.1 bits (157), Expect = 3e-10
Identities = 123/548 (22%), Positives = 205/548 (37%), Gaps = 95/548 (17%)
Query: 299 EVKKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEE------ERWRRKVICKEEPV 352
E KE+ ++ + G+ L P G E E+ +K++ KE +
Sbjct: 28 EELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGTFSREALMAYWEKESQKLLEKER-L 86
Query: 353 SEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLE 412
E + + EE+ + + I ++ + S+E + EEEEE+D+ E E +E
Sbjct: 87 GECGKVAEDKEES----EEELIFTESNSEVSEEVYTEEEEEESQEEEEEEDSDEEERTIE 142
Query: 413 RKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSS 472
K +G+V+ S SD S+P K+F + E+ + ++
Sbjct: 143 TAKGI-------NGTVNYDSVNSDNSKP----------------KIF--KSQIENINLTN 177
Query: 473 SKTGRDTPEN------GETAIGAENSEKIDENSDKEMEVE-ESPEKIKVQTTPKVEE--E 523
GR+T G + + +KI N EV + E I QT + E +
Sbjct: 178 GSNGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALK 237
Query: 524 QDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWRE-----GALNGNYL 578
+ + LANT + I N H+ + E+ + AL N +
Sbjct: 238 DNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTV 297
Query: 579 KRKL-----------QDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFP 627
+L Q E +K + N T H++ R + + +
Sbjct: 298 LTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQ-- 355
Query: 628 DGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLM 687
++ +E + QE D +T + GT S+S S + +V +
Sbjct: 356 -RQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHS-PWSSPKLPKKVQTVRSR 413
Query: 688 PLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPES---PPPPPPPPPPAEDGE-----IQE 739
PL+P T PP P PPPPPPPP S PPPPPPPPPP + + I E
Sbjct: 414 PLSPVAT---------PPPPP---PPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAE 461
Query: 740 VEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEIST- 798
V + E ++ G ++ K Q + + +S + ++ K E S+
Sbjct: 462 VIKQQESAQRALQNGQKKKKGKKVKKQPNSILKE--------IKNSLRSVQEKKMEDSSR 513
Query: 799 -AVVQRSA 805
+ QRSA
Sbjct: 514 PSTPQRSA 521
Score = 59.3 bits (142), Expect = 2e-08
Identities = 47/145 (32%), Positives = 65/145 (44%), Gaps = 31/145 (21%)
Query: 888 LQPVQARGAVPTATIIEPPPPPPPPPP-----PPPPAPKMPP-PEK-------------- 927
+Q V++R P AT PPPPPPPPPP PPPP P PP PEK
Sbjct: 407 VQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQ 466
Query: 928 ------TKKGRKDKAKKSKTKMP-SLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEE 980
+ G+K K K K P S++K+ ++ R + E+ SS R ST Q+ E
Sbjct: 467 ESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSS---RPSTPQRSAHE 523
Query: 981 WKQQQLVSGMAERNANFEALPEDWR 1005
+ + G + + +PE R
Sbjct: 524 -NLMEAIRGSSIKQLKRVEVPEALR 547
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 64.7 bits (156), Expect = 4e-10
Identities = 79/293 (26%), Positives = 103/293 (35%), Gaps = 69/293 (23%)
Query: 705 PPLPLEMPPPPPP---------------PPESPPPPPPPPPPA--------------EDG 735
PP P PPP P E PPP P PPPA E
Sbjct: 389 PPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPV 448
Query: 736 EIQEVEMEDEGSEE------------PPAPGTE--EDTPLKPSAQTTVVTSQSSVDST-- 779
+ + ++D G++ PP G + P P+A T VV ++ +
Sbjct: 449 VMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARP 508
Query: 780 -------ISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQS--------AIATGHQ 824
+S + G+ A+ ++ V + PVL +Q A AT
Sbjct: 509 SHPGGPPVSGTLQGAGLGTNAS-LAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567
Query: 825 AAGIGNQATGIGHQ----TIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVP 880
+AG N AT G P P M + L N LG A P S
Sbjct: 568 SAGTTNTATTAGPAPGGPAQPPPTPQPSMA-DLQFSQLLGNLLG-PAGPGAGGSGVASPT 625
Query: 881 IGVTAPSLQP-VQARGAVPTATIIEPPPPPPPPPPPPPPAPK-MPPPEKTKKG 931
I V P + +Q AT PPPPPPPPPPPP P + MPPP G
Sbjct: 626 ITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGG 678
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 20/135 (14%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEI 737
SG S + + + LQ LQ PPPPPPPP P PPP
Sbjct: 619 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS---- 674
Query: 738 QEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEIS 797
G+ P G E L P T+V V +SS + G + ++E
Sbjct: 675 -----PSGGAGSPGGLGLES---LSPEFFTSV------VQGVLSSLLGSLGARAGSSESI 720
Query: 798 TAVVQRSATIGSSPV 812
A +QR + GSS +
Sbjct: 721 AAFIQRLS--GSSNI 733
Score = 40.8 bits (94), Expect = 0.007
Identities = 57/252 (22%), Positives = 84/252 (33%), Gaps = 39/252 (15%)
Query: 706 PLPLEMPPPPPPPPESPPP---------------PPPPPPPAEDGE----IQEVEMEDEG 746
P P PPP PP +P P PP P AE+ E Q E+
Sbjct: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
Query: 747 SEEPPAPGTEEDTPLKPSAQTTVVTSQ--SSVDSTI------------SSSSSTKGIKRK 792
+ P P E + P PS V Q ++S + +++++ +
Sbjct: 249 APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHE 308
Query: 793 ATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQ 852
E ++ +G S L + +A + H P+S M Q
Sbjct: 309 GREEDQRLIN---LVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQ 365
Query: 853 ARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPP-PPP 911
+ +Q N +G P AP P QA P++T +E PP
Sbjct: 366 QAAIPIQIN-VGTTVTMTGNGTRPPPTP-NAEAPPPGPGQASSVAPSSTNVESSAEGAPP 423
Query: 912 PPPPPPPAPKMP 923
P P PPPA P
Sbjct: 424 PGPAPPPATSHP 435
Score = 32.7 bits (73), Expect = 1.8
Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 7/103 (6%)
Query: 875 AECSVPIGVTAPSLQPVQARGAVPTATIIEP-----PPPPPPPPPPPPPAPKMPPPEKTK 929
++ S P+ AP +P++A A P P P P P P AP P P +
Sbjct: 212 SQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYV 271
Query: 930 KGRKDKAKKSKTKMPSLVKKWQSI--QRELDEEDNSSSSEEDR 970
+ ++ + P L + ++ + D +N EED+
Sbjct: 272 EVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQ 314
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 64.7 bits (156), Expect = 4e-10
Identities = 79/293 (26%), Positives = 103/293 (35%), Gaps = 69/293 (23%)
Query: 705 PPLPLEMPPPPPP---------------PPESPPPPPPPPPPA--------------EDG 735
PP P PPP P E PPP P PPPA E
Sbjct: 389 PPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPV 448
Query: 736 EIQEVEMEDEGSEE------------PPAPGTE--EDTPLKPSAQTTVVTSQSSVDST-- 779
+ + ++D G++ PP G + P P+A T VV ++ +
Sbjct: 449 VMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARP 508
Query: 780 -------ISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQS--------AIATGHQ 824
+S + G+ A+ ++ V + PVL +Q A AT
Sbjct: 509 SHPGGPPVSGTLQGAGLGTNAS-LAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567
Query: 825 AAGIGNQATGIGHQ----TIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVP 880
+AG N AT G P P M + L N LG A P S
Sbjct: 568 SAGTTNTATTAGPAPGGPAQPPPTPQPSMA-DLQFSQLLGNLLG-PAGPGAGGSGVASPT 625
Query: 881 IGVTAPSLQP-VQARGAVPTATIIEPPPPPPPPPPPPPPAPK-MPPPEKTKKG 931
I V P + +Q AT PPPPPPPPPPPP P + MPPP G
Sbjct: 626 ITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGG 678
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 20/135 (14%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEI 737
SG S + + + LQ LQ PPPPPPPP P PPP
Sbjct: 619 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS---- 674
Query: 738 QEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEIS 797
G+ P G E L P T+V V +SS + G + ++E
Sbjct: 675 -----PSGGAGSPGGLGLES---LSPEFFTSV------VQGVLSSLLGSLGARAGSSESI 720
Query: 798 TAVVQRSATIGSSPV 812
A +QR + GSS +
Sbjct: 721 AAFIQRLS--GSSNI 733
Score = 40.8 bits (94), Expect = 0.007
Identities = 57/252 (22%), Positives = 84/252 (33%), Gaps = 39/252 (15%)
Query: 706 PLPLEMPPPPPPPPESPPP---------------PPPPPPPAEDGE----IQEVEMEDEG 746
P P PPP PP +P P PP P AE+ E Q E+
Sbjct: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
Query: 747 SEEPPAPGTEEDTPLKPSAQTTVVTSQ--SSVDSTI------------SSSSSTKGIKRK 792
+ P P E + P PS V Q ++S + +++++ +
Sbjct: 249 APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHE 308
Query: 793 ATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQ 852
E ++ +G S L + +A + H P+S M Q
Sbjct: 309 GREEDQRLIN---LVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQ 365
Query: 853 ARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPP-PPP 911
+ +Q N +G P AP P QA P++T +E PP
Sbjct: 366 QAAIPIQIN-VGTTVTMTGNGTRPPPTP-NAEAPPPGPGQASSVAPSSTNVESSAEGAPP 423
Query: 912 PPPPPPPAPKMP 923
P P PPPA P
Sbjct: 424 PGPAPPPATSHP 435
Score = 32.7 bits (73), Expect = 1.8
Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 7/103 (6%)
Query: 875 AECSVPIGVTAPSLQPVQARGAVPTATIIEP-----PPPPPPPPPPPPPAPKMPPPEKTK 929
++ S P+ AP +P++A A P P P P P P AP P P +
Sbjct: 212 SQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYV 271
Query: 930 KGRKDKAKKSKTKMPSLVKKWQSI--QRELDEEDNSSSSEEDR 970
+ ++ + P L + ++ + D +N EED+
Sbjct: 272 EVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQ 314
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 64.7 bits (156), Expect = 4e-10
Identities = 79/293 (26%), Positives = 103/293 (35%), Gaps = 69/293 (23%)
Query: 705 PPLPLEMPPPPPP---------------PPESPPPPPPPPPPA--------------EDG 735
PP P PPP P E PPP P PPPA E
Sbjct: 389 PPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPV 448
Query: 736 EIQEVEMEDEGSEE------------PPAPGTE--EDTPLKPSAQTTVVTSQSSVDST-- 779
+ + ++D G++ PP G + P P+A T VV ++ +
Sbjct: 449 VMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARP 508
Query: 780 -------ISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQS--------AIATGHQ 824
+S + G+ A+ ++ V + PVL +Q A AT
Sbjct: 509 SHPGGPPVSGTLQGAGLGTNAS-LAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567
Query: 825 AAGIGNQATGIGHQ----TIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVP 880
+AG N AT G P P M + L N LG A P S
Sbjct: 568 SAGTTNTATTAGPAPGGPAQPPPTPQPSMA-DLQFSQLLGNLLG-PAGPGAGGSGVASPT 625
Query: 881 IGVTAPSLQP-VQARGAVPTATIIEPPPPPPPPPPPPPPAPK-MPPPEKTKKG 931
I V P + +Q AT PPPPPPPPPPPP P + MPPP G
Sbjct: 626 ITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGG 678
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 20/135 (14%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEI 737
SG S + + + LQ LQ PPPPPPPP P PPP
Sbjct: 619 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS---- 674
Query: 738 QEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEIS 797
G+ P G E L P T+V V +SS + G + ++E
Sbjct: 675 -----PSGGAGSPGGLGLES---LSPEFFTSV------VQGVLSSLLGSLGARAGSSESI 720
Query: 798 TAVVQRSATIGSSPV 812
A +QR + GSS +
Sbjct: 721 AAFIQRLS--GSSNI 733
Score = 40.8 bits (94), Expect = 0.007
Identities = 57/252 (22%), Positives = 84/252 (33%), Gaps = 39/252 (15%)
Query: 706 PLPLEMPPPPPPPPESPPP---------------PPPPPPPAEDGE----IQEVEMEDEG 746
P P PPP PP +P P PP P AE+ E Q E+
Sbjct: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
Query: 747 SEEPPAPGTEEDTPLKPSAQTTVVTSQ--SSVDSTI------------SSSSSTKGIKRK 792
+ P P E + P PS V Q ++S + +++++ +
Sbjct: 249 APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHE 308
Query: 793 ATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQ 852
E ++ +G S L + +A + H P+S M Q
Sbjct: 309 GREEDQRLIN---LVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQ 365
Query: 853 ARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPP-PPP 911
+ +Q N +G P AP P QA P++T +E PP
Sbjct: 366 QAAIPIQIN-VGTTVTMTGNGTRPPPTP-NAEAPPPGPGQASSVAPSSTNVESSAEGAPP 423
Query: 912 PPPPPPPAPKMP 923
P P PPPA P
Sbjct: 424 PGPAPPPATSHP 435
Score = 32.7 bits (73), Expect = 1.8
Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 7/103 (6%)
Query: 875 AECSVPIGVTAPSLQPVQARGAVPTATIIEP-----PPPPPPPPPPPPPAPKMPPPEKTK 929
++ S P+ AP +P++A A P P P P P P AP P P +
Sbjct: 212 SQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYV 271
Query: 930 KGRKDKAKKSKTKMPSLVKKWQSI--QRELDEEDNSSSSEEDR 970
+ ++ + P L + ++ + D +N EED+
Sbjct: 272 EVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQ 314
>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
Length = 1132
Score = 64.7 bits (156), Expect = 4e-10
Identities = 79/293 (26%), Positives = 103/293 (35%), Gaps = 69/293 (23%)
Query: 705 PPLPLEMPPPPPP---------------PPESPPPPPPPPPPA--------------EDG 735
PP P PPP P E PPP P PPPA E
Sbjct: 395 PPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPV 454
Query: 736 EIQEVEMEDEGSEE------------PPAPGTE--EDTPLKPSAQTTVVTSQSSVDST-- 779
+ + ++D G++ PP G + P P+A T VV ++ +
Sbjct: 455 VMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARP 514
Query: 780 -------ISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQS--------AIATGHQ 824
+S + G+ A+ ++ V + PVL +Q A AT
Sbjct: 515 SHPGGPPVSGTLQGAGLGTNAS-LAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 573
Query: 825 AAGIGNQATGIGHQ----TIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVP 880
+AG N AT G P P M + L N LG A P S
Sbjct: 574 SAGTTNTATTAGPAPGGPAQPPPTPQPSMA-DLQFSQLLGNLLG-PAGPGAGGSGVASPT 631
Query: 881 IGVTAPSLQP-VQARGAVPTATIIEPPPPPPPPPPPPPPAPK-MPPPEKTKKG 931
I V P + +Q AT PPPPPPPPPPPP P + MPPP G
Sbjct: 632 ITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGG 684
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 20/135 (14%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEI 737
SG S + + + LQ LQ PPPPPPPP P PPP
Sbjct: 625 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS---- 680
Query: 738 QEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEIS 797
G+ P G E L P T+V V +SS + G + ++E
Sbjct: 681 -----PSGGAGSPGGLGLES---LSPEFFTSV------VQGVLSSLLGSLGARAGSSESI 726
Query: 798 TAVVQRSATIGSSPV 812
A +QR + GSS +
Sbjct: 727 AAFIQRLS--GSSNI 739
Score = 40.8 bits (94), Expect = 0.007
Identities = 57/252 (22%), Positives = 84/252 (33%), Gaps = 39/252 (15%)
Query: 706 PLPLEMPPPPPPPPESPPP---------------PPPPPPPAEDGE----IQEVEMEDEG 746
P P PPP PP +P P PP P AE+ E Q E+
Sbjct: 195 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 254
Query: 747 SEEPPAPGTEEDTPLKPSAQTTVVTSQ--SSVDSTI------------SSSSSTKGIKRK 792
+ P P E + P PS V Q ++S + +++++ +
Sbjct: 255 APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHE 314
Query: 793 ATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQ 852
E ++ +G S L + +A + H P+S M Q
Sbjct: 315 GREEDQRLIN---LVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQ 371
Query: 853 ARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPP-PPP 911
+ +Q N +G P AP P QA P++T +E PP
Sbjct: 372 QAAIPIQIN-VGTTVTMTGNGTRPPPTP-NAEAPPPGPGQASSVAPSSTNVESSAEGAPP 429
Query: 912 PPPPPPPAPKMP 923
P P PPPA P
Sbjct: 430 PGPAPPPATSHP 441
Score = 32.7 bits (73), Expect = 1.8
Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 7/103 (6%)
Query: 875 AECSVPIGVTAPSLQPVQARGAVPTATIIEP-----PPPPPPPPPPPPPAPKMPPPEKTK 929
++ S P+ AP +P++A A P P P P P P AP P P +
Sbjct: 218 SQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYV 277
Query: 930 KGRKDKAKKSKTKMPSLVKKWQSI--QRELDEEDNSSSSEEDR 970
+ ++ + P L + ++ + D +N EED+
Sbjct: 278 EVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQ 320
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 64.3 bits (155), Expect = 6e-10
Identities = 78/299 (26%), Positives = 101/299 (33%), Gaps = 50/299 (16%)
Query: 701 PVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTP 760
P P P PPP P E P PP PPP A P P TE + P
Sbjct: 508 PAAPPAAPSTPAPPPAVPKELPAPPAPPPASA------------------PTPETEPEEP 549
Query: 761 LK-PSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAI 819
+ P AQ+T ++ + +S ST + E S Q + G P +
Sbjct: 550 AQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPP--EEVPP 607
Query: 820 ATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSL--------QSNYLGLAAAPAI 871
T + + GIG P P+ G+G+ SL Q L
Sbjct: 608 PTTPPVPKVEPKGDGIGPTRQP---PSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQW 664
Query: 872 MSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPP----------PPPPPP---PP 918
+ + S P PS GAVP + PPPPP PPP PP P
Sbjct: 665 QQHQQGSAPPTPVPPSPPQPVTLGAVPAP---QAPPPPPKALYPGALGRPPPMPPMNFDP 721
Query: 919 APKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKR 977
M PP R + + P V + RE + SSS DR + A R
Sbjct: 722 RWMMIPPYVDP--RLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLR 778
Score = 44.7 bits (104), Expect = 5e-04
Identities = 72/320 (22%), Positives = 116/320 (36%), Gaps = 43/320 (13%)
Query: 628 DGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLM 687
D E ++ + A E D T + ++ G DS+ E + G +S SG+
Sbjct: 319 DQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDE----EGAEGHRDSQSASGEERP---- 370
Query: 688 PLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPP---PPPPPAEDGEI----QEV 740
P + N P +PP P PPE+ P PP PP PP G
Sbjct: 371 ---PEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPG 427
Query: 741 EMEDEGSE--EPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEIST 798
+ D G +PPAP E++ + Q+ +S+ S+ + + +R E
Sbjct: 428 DYPDRGGPPCKPPAPEDEDEAWRQRRKQS---SSEISLAVERARRRREEEERRMQEERRA 484
Query: 799 AVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSL 858
A ++ + + AA +T +P LPA A +
Sbjct: 485 ACAEKLKRLDEK--FGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTP 542
Query: 859 QSN--------------YLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIE 904
++ G+AAAP ++S + + PV+ + +P+
Sbjct: 543 ETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQ--LPSKE--G 598
Query: 905 PPPPPPPPPPPPPPAPKMPP 924
P PP PPP PP PK+ P
Sbjct: 599 PEPPEEVPPPTTPPVPKVEP 618
Score = 36.2 bits (82), Expect = 0.16
Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 19/107 (17%)
Query: 708 PLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAP-GTE---------E 757
PL P PP PP PPP P DG+ +E+ E PP P GTE E
Sbjct: 1692 PLNAVPCEGPPGSEPPRRPPPAP--HDGDRKELPRE---QPLPPGPIGTERSQRTDRGTE 1746
Query: 758 DTPLKPSAQ----TTVVTSQSSVDSTISSSSSTKGIKRKATEISTAV 800
P++PS + TS D + S K K ++ A+
Sbjct: 1747 PGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAI 1793
Score = 35.0 bits (79), Expect = 0.36
Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 4/77 (5%)
Query: 31 PEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAA--AASDDSPSEDEQEAVQEVPRVVQN 88
P+ EP + A PS PAP A A AS +P + +E Q P Q+
Sbjct: 500 PDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPP--AQS 557
Query: 89 PPKPVMTTRPTAVKATG 105
P P + PT V G
Sbjct: 558 TPTPGVAAAPTLVSGGG 574
Score = 34.7 bits (78), Expect = 0.47
Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 18/111 (16%)
Query: 3 KKSRAVPGRRPILQLSPPG-----PRGSTPGRDPEPEPDTEPDSTAAVP---SQPAPSAA 54
K A P P PP P P P P+TEP+ A P S P P A
Sbjct: 505 KAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVA 564
Query: 55 TTTT-------TAVTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRP 98
T T+ T++ + + SP E + + +E P + P P TT P
Sbjct: 565 AAPTLVSGGGSTSSTSSGSFEASPVEPQLPS-KEGPEPPEEVPPP--TTPP 612
Score = 34.7 bits (78), Expect = 0.47
Identities = 26/96 (27%), Positives = 32/96 (33%), Gaps = 5/96 (5%)
Query: 7 AVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVP---SQPAPSAATTTTTAVTA 63
+ P P + P P P P PE TEP+ A P S P P A T
Sbjct: 516 STPAPPPAVPKELPAPPAPPPASAPTPE--TEPEEPAQAPPAQSTPTPGVAAAPTLVSGG 573
Query: 64 AAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPT 99
+ S S E V+ + P P PT
Sbjct: 574 GSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPT 609
Score = 33.9 bits (76), Expect = 0.80
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 23/114 (20%)
Query: 886 PSLQPVQARGAVPTATIIEPPPP-PPPPPP---------PPPPAP-------KMPPPEKT 928
P+ + A + P T PP P PP PPP PP P K P PE
Sbjct: 386 PTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDE 445
Query: 929 KKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQ--KRIEE 980
+ + + K+S +++ V++ R EE+ EE R + A+ KR++E
Sbjct: 446 DEAWRQRRKQSSSEISLAVER----ARRRREEEERRMQEERRAACAEKLKRLDE 495
Score = 33.1 bits (74), Expect = 1.4
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 4/62 (6%)
Query: 701 PVLQPPLPLEMPPPPPPP----PESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTE 756
P+ +PP P ++ PP P E+P PP P P G++ + PAP
Sbjct: 951 PIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLR 1010
Query: 757 ED 758
D
Sbjct: 1011 RD 1012
Score = 32.0 bits (71), Expect = 3.0
Identities = 16/43 (37%), Positives = 19/43 (44%)
Query: 701 PVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEME 743
P LQPP PPP P P P P P E+ VE++
Sbjct: 2014 PALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPVELK 2056
Score = 31.6 bits (70), Expect = 4.0
Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 710 EMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPP-APGTEE 757
E PP PPPPP P P A I +E+ G P PG++E
Sbjct: 824 ETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDE 872
Score = 31.6 bits (70), Expect = 4.0
Identities = 16/50 (32%), Positives = 20/50 (40%), Gaps = 3/50 (6%)
Query: 879 VPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPP---PPPAPKMPPP 925
+P G A + +P PP PPP PPP P P + PP
Sbjct: 1970 LPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPP 2019
Score = 31.2 bits (69), Expect = 5.2
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 14/83 (16%)
Query: 696 LQSNVPVLQPPLPL--------EMPPPPPP----PPESPPPPPPPPPPAED--GEIQEVE 741
++S P + PP P E P PP P E P P P P PP D +IQ
Sbjct: 821 MRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPP 880
Query: 742 MEDEGSEEPPAPGTEEDTPLKPS 764
+ E +E A T + KP+
Sbjct: 881 PKKEPPKEETAQLTGPEAGRKPA 903
Score = 30.4 bits (67), Expect = 8.8
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 4/51 (7%)
Query: 712 PPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLK 762
P P PP P PPPP + E+ +E +G E P P + PLK
Sbjct: 939 PEEPGAPPRRAGPIKKPPPPTKVEELPPKPLE-QGDETPKPP---KPDPLK 985
Score = 30.4 bits (67), Expect = 8.8
Identities = 34/154 (22%), Positives = 50/154 (32%), Gaps = 28/154 (18%)
Query: 713 PPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEP-----------PAPGTE----- 756
PP PP P PPPPP A Q + G ++ APG
Sbjct: 1442 PPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKP 1501
Query: 757 --EDTPLKPSAQTTVVTSQSSVDSTISSS----------SSTKGIKRKATEISTAVVQRS 804
P PS + V+S +SS G R + +S +R
Sbjct: 1502 GLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRR 1561
Query: 805 ATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQ 838
P L + ++ H + +G++ G G Q
Sbjct: 1562 ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQ 1595
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 62.0 bits (149), Expect = 3e-09
Identities = 61/245 (24%), Positives = 76/245 (31%), Gaps = 96/245 (39%)
Query: 703 LQPPLPLEMPPPPPPPPESPPPPPP--PPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTP 760
+ PP P+ M PPPPPPP PPPPP P PP + + + PP+ TP
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ------QQQQPPPPPPPSSSMASSTP 522
Query: 761 LKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIA 820
L TT T+ SA GS P Q A A
Sbjct: 523 LPWQQNTTTTTT-------------------------------SAGTGSIPPWQQQQAAA 551
Query: 821 TGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVP 880
A +Q N + P + P
Sbjct: 552 AASPGA-----------------------------PQMQGNPTMVPLPPGVQP------P 576
Query: 881 IGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPP-------------------PPAPK 921
+ AP P G +A ++ PPPPPPPP P PPAP
Sbjct: 577 LPPGAPPPPPPPPPG---SAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633
Query: 922 MPPPE 926
PPP+
Sbjct: 634 PPPPQ 638
Score = 55.5 bits (132), Expect = 3e-07
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 12/105 (11%)
Query: 661 STESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPV---LQPPLPLEMPPPPPP 717
+T ++ TS G+ + Q ++++ P P + VP+ +QPPLP PPPPPP
Sbjct: 528 NTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP 587
Query: 718 PPES------PPPPPPPPPPAEDGEIQEVEMEDEGSEE---PPAP 753
PP PPPPPPPP + + M G PPAP
Sbjct: 588 PPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAP 632
Score = 55.1 bits (131), Expect = 3e-07
Identities = 61/237 (25%), Positives = 79/237 (33%), Gaps = 65/237 (27%)
Query: 706 PLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEM--------EDEGSEEPPAPGTEE 757
P P M PPPPP + P PP PP D + + + +G PP G
Sbjct: 420 PPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP 479
Query: 758 DTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQS 817
P PS Q S +++ + S+ S+P+ + Q+
Sbjct: 480 PPPPPPSGQPPP-----------PPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Query: 818 AIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAI--MSYA 875
T T G +IP Q AA+P M
Sbjct: 529 TTTT----------TTSAGTGSIP---------------PWQQQQAAAAASPGAPQMQGN 563
Query: 876 ECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPP--------PPPPPAPKMPP 924
VP+ P +QP GA PPPPPPPPP PPPPP P M P
Sbjct: 564 PTMVPL---PPGVQPPLPPGA--------PPPPPPPPPGSAGMMYAPPPPPPPPMDP 609
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 12/108 (11%)
Query: 878 SVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAK 937
S P+G L + P ++ PPPPPP PPPPP+ +PP ++ ++
Sbjct: 453 STPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPP 512
Query: 938 KSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQ 985
S + S WQ ++ S I W+QQQ
Sbjct: 513 PSSSMASSTPLPWQ------------QNTTTTTTSAGTGSIPPWQQQQ 548
Score = 38.5 bits (88), Expect = 0.032
Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Query: 19 PPGPRGSTPG--RDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQ 76
PP P G P + + P P S++ S P P TTTT T+A P + +Q
Sbjct: 490 PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTT-TSAGTGSIPPWQQQQ 548
Query: 77 EAVQEVPRVVQNPPKPVMTTRPTAVK 102
A P Q P M P V+
Sbjct: 549 AAAAASPGAPQMQGNPTMVPLPPGVQ 574
Score = 30.8 bits (68), Expect = 6.8
Identities = 15/27 (55%), Positives = 15/27 (55%), Gaps = 7/27 (25%)
Query: 906 PPPP---PPPPP----PPPPAPKMPPP 925
PPPP PPPPP P PP PPP
Sbjct: 420 PPPPWMQPPPPPMNQGPHPPGHHGPPP 446
Score = 30.4 bits (67), Expect = 8.8
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 20/77 (25%)
Query: 158 PQPAAPVGASAPPPTPP---------RPEPKEAATSTLSSST-----SNGTDSTQTSG-- 201
P P P G PPP+ P +P P +S+++SST N T +T ++G
Sbjct: 480 PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTG 539
Query: 202 ----WQYDTQCSLAGVG 214
WQ + A G
Sbjct: 540 SIPPWQQQQAAAAASPG 556
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 59.3 bits (142), Expect = 2e-08
Identities = 95/417 (22%), Positives = 149/417 (35%), Gaps = 77/417 (18%)
Query: 576 NYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEE- 634
NY KR Q+ E L+Q+++ +R+ RR + + FP E+EE
Sbjct: 655 NYKKR--QNLDEILQQHKLKMEK-------ERNARRKKKKAPAAASEEAAFPPVVEDEEM 705
Query: 635 ESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLM------- 687
E+ +E + ++ + T +S+ TES + K++ + +
Sbjct: 706 EASGVSGNEEEMVEEA--EATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 763
Query: 688 -PLTPFWTLLQSNVPVLQPPLPLE------MPPPPPPPPESPPPPPPPP---------PP 731
P TP ++P P P PPP PP P +PPP P PP
Sbjct: 764 GPPTP----PPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPP 819
Query: 732 AEDGEIQ------EVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSS 785
E+GE Q E+ ++ +EEP E+ P+ ++++ + + +
Sbjct: 820 VEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKK 879
Query: 786 TKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTI-PVSL 844
G R T S+ Q S + + SA G N+ + P
Sbjct: 880 EGGSGRATTAKSSGAPQDSDSSATC------SADEVDEAEGGDKNRLLSPRPSLLTPTGD 933
Query: 845 PAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIE 904
P A Q + + L+ AA P PI VT P A PT +
Sbjct: 934 PRANASPQ-KPLDLKQLKQRAAAIP----------PIQVTKVHEPP--REDAAPT----K 976
Query: 905 PPPPPPPPP---PPPPPAPKMPPPEKTKKGRK-----DKAKKSKTKMPSLVKKWQSI 953
P PP PPPP P AP+ P K R DK + P+ + Q +
Sbjct: 977 PAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL 1033
Score = 40.8 bits (94), Expect = 0.007
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 125 EKLAQSKETNGNQSTDIDSTLANFL--AEIDAITAPQPAAPVGASAPPPTPPRPEPKEAA 182
E++ + E N S+D +S + A+ P+P A +GA PPP PP P P++
Sbjct: 715 EEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIP 774
Query: 183 TSTLSSSTSNGT 194
T + S T
Sbjct: 775 APTEPTPASEAT 786
Score = 39.7 bits (91), Expect = 0.015
Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 895 GAVPTATIIE--PPPPPPPPPPPPPPAPKMPPP--EKTKKGRKDKAKKSKTKMPSLVKKW 950
G P AT+ PPP PP PPP PAP P P E T A S + P +V K
Sbjct: 749 GPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPK- 807
Query: 951 QSIQRELDEEDNSSSSEEDRESTAQKRIEE 980
E +EE ++ E+ E EE
Sbjct: 808 ----EEKEEETAAAPPVEEGEEQKPPAAEE 833
Score = 34.7 bits (78), Expect = 0.47
Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 14/119 (11%)
Query: 880 PIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPP----PPPPAPKMPPPEKT------K 929
P G P + + A A+ P PPP PP PPP PK E+T +
Sbjct: 762 PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVE 821
Query: 930 KGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSE----EDRESTAQKRIEEWKQQ 984
+G + K ++ K + ++ E EE ++ E E+TA+ ++ K++
Sbjct: 822 EGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKE 880
Score = 32.3 bits (72), Expect = 2.3
Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 9/80 (11%)
Query: 20 PGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDS-----PSED 74
P P + P P P T P P++P P++ T A S + P E+
Sbjct: 750 PKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEE 809
Query: 75 EQEAVQEVPRV----VQNPP 90
++E P V Q PP
Sbjct: 810 KEEETAAAPPVEEGEEQKPP 829
Score = 32.0 bits (71), Expect = 3.0
Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 907 PPPPPPPPPPPPAPKMPPPEKTKK---GRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNS 963
P PP PP P ++ PP +K+ D+ + T + + K + Q++L+EE +
Sbjct: 147 PVSPPSPPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEE--A 204
Query: 964 SSSEEDRESTAQKRIEEWKQQQLVSGMAERN 994
+ E + + IE K + LV + + N
Sbjct: 205 AKPPEPEKPVSPPPIES-KHRSLVQIIYDEN 234
Score = 31.6 bits (70), Expect = 4.0
Identities = 51/192 (26%), Positives = 69/192 (35%), Gaps = 18/192 (9%)
Query: 746 GSEEPPAPGTE--EDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQR 803
GS PA + + +P+ P Q + S + +T KGI A E ST V R
Sbjct: 1837 GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNT-----GMKGIIT-AVEPSTPTVLR 1890
Query: 804 SATIGSSPVLYSQSAIATGHQAAG---IGNQATGIGHQTIPVSLPAAGMGHQARGMSLQS 860
S T SSPV + + H G G T + +P P + R +
Sbjct: 1891 S-TSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRA---DT 1946
Query: 861 NYLGLAAAPAIMSYAECSVPIGVTAPS--LQPVQARGAVPTATIIEPPPPPPPPPPPPPP 918
+ LA PA S P + P + PV + P P PP PP
Sbjct: 1947 GHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPP 2006
Query: 919 APKMPP-PEKTK 929
A P EKT+
Sbjct: 2007 ASASDPHREKTQ 2018
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 58.9 bits (141), Expect = 2e-08
Identities = 76/290 (26%), Positives = 107/290 (36%), Gaps = 65/290 (22%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPP--PP------------PPPESPP 723
+G +S P++P L VP + P P+ +PPP PP PP +PP
Sbjct: 629 NGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPP 688
Query: 724 ------------PPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLK-PSAQTTVV 770
PPPPPPPP + + PP P P+ P T +
Sbjct: 689 LGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPP--GFLPPGPPPPITPPVSIPPPHTPPI 746
Query: 771 TSQSSVDSTISSSSSTKGIKRKATEISTAV--VQRSATIGSSPVLYSQSAIATGHQAAGI 828
+ +S + I + +TK + I T V + +A G S +Y +
Sbjct: 747 SIPNSTIAGI-NEDTTKDLS-IGNPIPTVVSGARGNAESGDSVKMYGSAV---------- 794
Query: 829 GNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSL 888
A T PV+ P + +G Q G+A P I A + +G P L
Sbjct: 795 -PPAAPTNLPTPPVTQPVSLLGTQ-----------GVAPGPVIGLQAPSTGLLG-ARPGL 841
Query: 889 QPVQARGAVPTATIIEPPPPPPPPPPP------PPPAP---KMPPPEKTK 929
P+Q +P + P PP P PP PPP P MPPP K
Sbjct: 842 IPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMK 891
Score = 35.8 bits (81), Expect = 0.21
Identities = 49/184 (26%), Positives = 66/184 (35%), Gaps = 43/184 (23%)
Query: 18 SPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQE 77
SPP P + EP P+S AVP P+ A AA A ++ +Q
Sbjct: 139 SPPPPVKVSS----EPPTQATPNSVPAVPQLPSSDAF--------AAVAQLFQTTQGQQ- 185
Query: 78 AVQEVPRVVQNPPKPVMTTRPTAVKA-----TGGLCLLGAYADSDD-------------- 118
+Q++ + Q PPKP AV A T L
Sbjct: 186 -LQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDK 244
Query: 119 ------DDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPT 172
D +D E + +SK+ + T +T A A A TA PAA A+A PP
Sbjct: 245 KLLDRFDYDDEPEAVEESKK----EDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPP 300
Query: 173 PPRP 176
P P
Sbjct: 301 PQAP 304
Score = 32.3 bits (72), Expect = 2.3
Identities = 45/254 (17%), Positives = 80/254 (31%), Gaps = 30/254 (11%)
Query: 724 PPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSS 783
PP P P ++ + +V+ + P +E+ P Q T + +
Sbjct: 196 PPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKK--LLDRFDYD 253
Query: 784 SSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVS 843
+ ++ E +TAV + P T A A P
Sbjct: 254 DEPEAVEESKKEDTTAVTTTAPAAAVPPA-------PTATVPAAAAPAAASPPPPQAPFG 306
Query: 844 LPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATII 903
P GM A + P +M + + V P+ G +P ++
Sbjct: 307 FPGDGMQQPAYTQHQNMDQF----QPRMMGIQQDPMHHQV------PLPPNGQMPGFGLL 356
Query: 904 EPPPPPPPPPPPPPPAPKMPPP-------EKTKKGRKDKAKKSKTKMPSLVKKWQSIQRE 956
PP PP P PP P + P + +K ++ + + P + Q ++R
Sbjct: 357 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCI----QEVKRH 412
Query: 957 LDEEDNSSSSEEDR 970
+ + S S R
Sbjct: 413 MSDNRKSRSRSASR 426
Score = 30.8 bits (68), Expect = 6.8
Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 3/39 (7%)
Query: 903 IEPPPPPPPPPP---PPPPAPKMPPPEKTKKGRKDKAKK 938
+ P PPPP PP PPP P + P T G + K
Sbjct: 724 LPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTK 762
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 58.9 bits (141), Expect = 2e-08
Identities = 76/290 (26%), Positives = 107/290 (36%), Gaps = 65/290 (22%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPP--PP------------PPPESPP 723
+G +S P++P L VP + P P+ +PPP PP PP +PP
Sbjct: 644 NGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPP 703
Query: 724 ------------PPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLK-PSAQTTVV 770
PPPPPPPP + + PP P P+ P T +
Sbjct: 704 LGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPP--GFLPPGPPPPITPPVSIPPPHTPPI 761
Query: 771 TSQSSVDSTISSSSSTKGIKRKATEISTAV--VQRSATIGSSPVLYSQSAIATGHQAAGI 828
+ +S + I + +TK + I T V + +A G S +Y +
Sbjct: 762 SIPNSTIAGI-NEDTTKDLS-IGNPIPTVVSGARGNAESGDSVKMYGSAV---------- 809
Query: 829 GNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSL 888
A T PV+ P + +G Q G+A P I A + +G P L
Sbjct: 810 -PPAAPTNLPTPPVTQPVSLLGTQ-----------GVAPGPVIGLQAPSTGLLG-ARPGL 856
Query: 889 QPVQARGAVPTATIIEPPPPPPPPPPP------PPPAP---KMPPPEKTK 929
P+Q +P + P PP P PP PPP P MPPP K
Sbjct: 857 IPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMK 906
Score = 35.8 bits (81), Expect = 0.21
Identities = 49/184 (26%), Positives = 66/184 (35%), Gaps = 43/184 (23%)
Query: 18 SPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQE 77
SPP P + EP P+S AVP P+ A AA A ++ +Q
Sbjct: 154 SPPPPVKVSS----EPPTQATPNSVPAVPQLPSSDAF--------AAVAQLFQTTQGQQ- 200
Query: 78 AVQEVPRVVQNPPKPVMTTRPTAVKA-----TGGLCLLGAYADSDD-------------- 118
+Q++ + Q PPKP AV A T L
Sbjct: 201 -LQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDK 259
Query: 119 ------DDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPT 172
D +D E + +SK+ + T +T A A A TA PAA A+A PP
Sbjct: 260 KLLDRFDYDDEPEAVEESKK----EDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPP 315
Query: 173 PPRP 176
P P
Sbjct: 316 PQAP 319
Score = 32.3 bits (72), Expect = 2.3
Identities = 45/254 (17%), Positives = 80/254 (31%), Gaps = 30/254 (11%)
Query: 724 PPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSS 783
PP P P ++ + +V+ + P +E+ P Q T + +
Sbjct: 211 PPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKK--LLDRFDYD 268
Query: 784 SSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVS 843
+ ++ E +TAV + P T A A P
Sbjct: 269 DEPEAVEESKKEDTTAVTTTAPAAAVPPA-------PTATVPAAAAPAAASPPPPQAPFG 321
Query: 844 LPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATII 903
P GM A + P +M + + V P+ G +P ++
Sbjct: 322 FPGDGMQQPAYTQHQNMDQF----QPRMMGIQQDPMHHQV------PLPPNGQMPGFGLL 371
Query: 904 EPPPPPPPPPPPPPPAPKMPPP-------EKTKKGRKDKAKKSKTKMPSLVKKWQSIQRE 956
PP PP P PP P + P + +K ++ + + P + Q ++R
Sbjct: 372 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCI----QEVKRH 427
Query: 957 LDEEDNSSSSEEDR 970
+ + S S R
Sbjct: 428 MSDNRKSRSRSASR 441
Score = 30.8 bits (68), Expect = 6.8
Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 3/39 (7%)
Query: 903 IEPPPPPPPPPP---PPPPAPKMPPPEKTKKGRKDKAKK 938
+ P PPPP PP PPP P + P T G + K
Sbjct: 739 LPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTK 777
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 58.9 bits (141), Expect = 2e-08
Identities = 30/67 (44%), Positives = 35/67 (52%), Gaps = 18/67 (26%)
Query: 701 PVLQPPLPLEMPPPPPPPPESPPPPPPPPPPA------------------EDGEIQEVEM 742
P PP P E PPPP PPP S P PPP P A EDGE++E E+
Sbjct: 5 PGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGEL 64
Query: 743 EDEGSEE 749
ED+G+EE
Sbjct: 65 EDDGAEE 71
Score = 47.4 bits (111), Expect = 7e-05
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 9/67 (13%)
Query: 880 PIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKS 939
P T+P+ +P+Q PPPPPPPPPPP PP MP E + +
Sbjct: 526 PQAPTSPNGRPMQGG---------PPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMY 576
Query: 940 KTKMPSL 946
K+PSL
Sbjct: 577 NKKIPSL 583
Score = 42.7 bits (99), Expect = 0.002
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 708 PLEMPPPPPPPPESPPPPPP--PPPPAEDGEIQEVEMEDEGSEEPPA 752
P++ PPPPPPP PPP PP P P E Q+++ +D +++ P+
Sbjct: 536 PMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPS 582
Score = 41.2 bits (95), Expect = 0.005
Identities = 16/24 (66%), Positives = 17/24 (70%), Gaps = 3/24 (12%)
Query: 905 PPPPP---PPPPPPPPPAPKMPPP 925
PPPPP PPPP PPPP+ PPP
Sbjct: 8 PPPPPSESPPPPSPPPPSTPSPPP 31
Score = 40.8 bits (94), Expect = 0.007
Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 4/110 (3%)
Query: 905 PPPP---PPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEED 961
PPPP PPPP PPPP P PP + + +P + + + EL E+D
Sbjct: 9 PPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGEL-EDD 67
Query: 962 NSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRR 1011
+ +++ + R E+ ++ S + + + + R + KRR
Sbjct: 68 GAEETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRR 117
Score = 39.7 bits (91), Expect = 0.015
Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 13/51 (25%)
Query: 701 PVLQPP-----LPLEMPPPPPPPPESP--------PPPPPPPPPAEDGEIQ 738
P+ +PP LP PP P P SP PPPPPPPPP G Q
Sbjct: 506 PLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQ 556
Score = 37.7 bits (86), Expect = 0.055
Identities = 19/45 (42%), Positives = 20/45 (44%)
Query: 880 PIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 924
P GV P PT+ P PPPPPPPPP P PP
Sbjct: 511 PPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPP 555
Score = 37.4 bits (85), Expect = 0.072
Identities = 46/183 (25%), Positives = 67/183 (36%), Gaps = 14/183 (7%)
Query: 31 PEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQEAVQEVPRVVQNPP 90
P P+ D P AA+ S P T AA A + + + + P
Sbjct: 988 PIPKQDAVPPVPAALQSMP-----TLDPRLHRAATAGPPNARQRPGASTDSSTQGANLPD 1042
Query: 91 KPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLA 150
+++ V ATG G S D +D + A T+ DST ++ A
Sbjct: 1043 FELLSRILKTVNATGSSAAPG----SSDKPSDPRVRKAP---TDPRLQKPTDSTASSRAA 1095
Query: 151 EIDAITAPQPAA-PVGASAPPPTPPRPEPKEAATSTLSSSTSNGTDSTQTSGWQYDTQCS 209
+ AP P A P G ++PP T P +P+ A L G S + YD +
Sbjct: 1096 KPGPAEAPSPTASPSGDASPPATAPY-DPRVLAAGGLGQGGGGGQSSVLSGISLYDPRTP 1154
Query: 210 LAG 212
AG
Sbjct: 1155 NAG 1157
Score = 35.8 bits (81), Expect = 0.21
Identities = 23/108 (21%), Positives = 40/108 (37%), Gaps = 15/108 (13%)
Query: 893 ARGAVPTATIIEPPPPPPPPPPPPPPAP---------------KMPPPEKTKKGRKDKAK 937
A G P PPPP PPPP P P P ++P P+ + G ++ +
Sbjct: 4 APGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGE 63
Query: 938 KSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQ 985
+R E+ S+ D E + ++ + K+++
Sbjct: 64 LEDDGAEETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKER 111
Score = 33.1 bits (74), Expect = 1.4
Identities = 19/53 (35%), Positives = 22/53 (41%), Gaps = 14/53 (26%)
Query: 886 PSLQPVQARGAVPTATIIEPPPPPP------------PPPPPPPPAPKMPPPE 926
P +P G +PT PP P PPPPPPPP P PP+
Sbjct: 506 PLPKPPPGVGLLPTPP--RPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQ 556
>gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
Length = 1596
Score = 57.8 bits (138), Expect = 5e-08
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 7/86 (8%)
Query: 893 ARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQS 952
AR A P + PPPPPP PPPPPPP P PP KT +G K +K K + P+ +
Sbjct: 1516 AREAPP----LPPPPPPPLPPPPPPPLPPPPPLPKTPRGGK---RKHKPQAPAQPPQQSP 1568
Query: 953 IQRELDEEDNSSSSEEDRESTAQKRI 978
Q+ L +E+ + + + ++ +
Sbjct: 1569 PQQPLPQEEEVKAKRQRKSRGSESEV 1594
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 705 PPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPS 764
PPLP PPP PPPP P PPPPP P G + + + PA ++ P +P
Sbjct: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGG------KRKHKPQAPAQPPQQSPPQQPL 1573
Query: 765 AQTTVVTSQSSVDSTISSS 783
Q V ++ S S S
Sbjct: 1574 PQEEEVKAKRQRKSRGSES 1592
Score = 32.3 bits (72), Expect = 2.3
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 17/95 (17%)
Query: 866 AAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPP---------------- 909
A+ IM+ E + + AP L P P PPPPP
Sbjct: 1500 ASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQA 1559
Query: 910 P-PPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKM 943
P PP PP +P E+ K R+ K++ S++++
Sbjct: 1560 PAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEV 1594
Score = 31.2 bits (69), Expect = 5.2
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 717 PPPESPPPPPPPPPPAEDGEIQE-VEMEDEGSEEPPAPGT 755
P P S P PP AE +Q V+ + G++EPP P T
Sbjct: 291 PSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPT 330
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 57.8 bits (138), Expect = 5e-08
Identities = 61/256 (23%), Positives = 91/256 (35%), Gaps = 28/256 (10%)
Query: 708 PLEMPPPPPPPPESP----PPPPPPPPPAEDGEIQEVEMEDEGSEEPPA--PGTEEDT-- 759
P++ P P PP + P P P PPA+ + + + G+ +PP PGT +
Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364
Query: 760 ---PLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQ 816
P KP AQ T SS + + G+ + + + +G+ L Q
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
Query: 817 SAIATGHQAAGIGNQATGIGHQTIPVSLPAAGM--GHQARGMSLQSNYLGLAAAPAIMSY 874
G+ + A G PV P G QA + G P+ +
Sbjct: 425 P---------GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP- 474
Query: 875 AECSVPIGVTAPSLQPVQARG-AVPTATIIEPPPPPPPPPPPPPPAPKMP----PPEKTK 929
P P+ P Q G A P + PPP P P P+P+ P PP +
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Query: 930 KGRKDKAKKSKTKMPS 945
K A++ PS
Sbjct: 535 GSAKPSAQQPSPAKPS 550
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/54 (51%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPP 731
SG S SSL P P S++ + P P PPPPPPPP PPPPPP PPP
Sbjct: 2378 SGSPSVSSL-PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Score = 54.3 bits (129), Expect = 6e-07
Identities = 19/25 (76%), Positives = 20/25 (80%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKTK 929
PPPPPPPPPPPPPP P +PPP K
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPK 2434
Score = 53.5 bits (127), Expect = 1e-06
Identities = 23/50 (46%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 879 VPIGVTAPSLQPVQARGAVPTATI---IEPPPPPPPPPPPPPPAPKMPPP 925
+P G + S P + R ++++ +PPPPPPPPPPPPPP P PPP
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 51.6 bits (122), Expect = 4e-06
Identities = 18/21 (85%), Positives = 18/21 (85%)
Query: 905 PPPPPPPPPPPPPPAPKMPPP 925
PPPPPPPPPPPPPP P PPP
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPP 2426
Score = 48.5 bits (114), Expect = 3e-05
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 73/371 (19%)
Query: 679 GQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPP-------PPPPPPESPPPPPPPPPP 731
G+ S+ P P L P Q P P + PP PP P S PPP P P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
Query: 732 AEDGEIQEVEMEDEGSEEPPA-------PGTEEDTPLKPSA-QTTVVTSQSSVDSTISSS 783
A+ + GS +PP+ P ++ +P KPSA Q+T SQ+ +
Sbjct: 517 AKPSP------QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Query: 784 SSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVS 843
+ + K+ ++ + P+ + + + A N T QT S
Sbjct: 571 TVSPSAKQPPSQGLPKTI--------CPLCNTTELLLHVPEKA---NFNTCTECQTTVCS 619
Query: 844 L----PAAGMGHQARGMSL---QSNYLG--LAAAPAI----MSYAECSVPIGVTAPSLQP 890
L P + + L LG LA P+ + A + V+ S QP
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679
Query: 891 VQA---RGAVPTATIIEPPPPPPPPP---------------PPPPPAPKM----PPPEKT 928
Q + A P + + P P PPP PP A + PP E +
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739
Query: 929 KKGRKDKA--KKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQL 986
+DKA K K P +VK +L ++++ + S Q + EE L
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKP----TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 987 VSGMAERNANF 997
+ A+ + +F
Sbjct: 796 KTDSAKPSQSF 806
Score = 47.4 bits (111), Expect = 7e-05
Identities = 17/24 (70%), Positives = 18/24 (75%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKT 928
PPPPPPPPPPPPPP P P+ T
Sbjct: 2413 PPPPPPPPPPPPPPLPPPTSPKPT 2436
Score = 46.6 bits (109), Expect = 1e-04
Identities = 20/40 (50%), Positives = 21/40 (52%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMP 944
PPPPPPPPPPPP P P P P K + A T P
Sbjct: 2415 PPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 40.0 bits (92), Expect = 0.011
Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 15/137 (10%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEI 737
S +V S + PL+P L + VP + PLP ++ P P+ PP P A+
Sbjct: 3619 SPKVLYSPISPLSPGKALESAFVPY-EKPLPDDISPQKVLHPDMAKVPPASPKTAK---- 3673
Query: 738 QEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKR-----K 792
M+ S+ P T +++ P T T++ S T++SS + K +KR
Sbjct: 3674 ---MMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGS--QTMTSSGAQKKVKRTLPNPP 3728
Query: 793 ATEISTAVVQRSATIGS 809
EIST +T+G+
Sbjct: 3729 PEEISTGTQSTFSTMGT 3745
Score = 38.5 bits (88), Expect = 0.032
Identities = 18/41 (43%), Positives = 20/41 (48%)
Query: 887 SLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEK 927
S QP P PPPPPPP PPP P P + P +K
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKK 2442
Score = 38.1 bits (87), Expect = 0.042
Identities = 46/210 (21%), Positives = 70/210 (33%), Gaps = 20/210 (9%)
Query: 9 PGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASD 68
P + P Q P P PG P +P ST P QP P+ + T +
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGS--AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ 533
Query: 69 DSPSEDEQEAVQEVPRVVQNPPKPVMTTR-------PTAVKATGGLCLLGAYADSDDDDN 121
++ + Q KPV T PT + G N
Sbjct: 534 PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCN 593
Query: 122 DVSEKLAQSKETNGNQSTDIDSTLANF--------LAEID---AITAPQPAAPVGASAPP 170
L ++ N N T+ +T+ + L E+ + A G AP
Sbjct: 594 TTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV 653
Query: 171 PTPPRPEPKEAATSTLSSSTSNGTDSTQTS 200
P+ P+P+ K A +T S+ + + QTS
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683
Score = 35.0 bits (79), Expect = 0.36
Identities = 35/157 (22%), Positives = 52/157 (33%), Gaps = 8/157 (5%)
Query: 25 STPGRDPEPEPDTEPDSTAAV---PSQPAPSAATTTTTAVTAAAASDDSPSEDEQEAVQE 81
S P EP +E D P QP TT + ++A D PS Q +E
Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 82 --VPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQST 139
P + + KP + PT K + D+ + S E+ G +
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSP---FDSKAIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 140 DIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRP 176
D ++ A P+ +P P PRP
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Score = 32.7 bits (73), Expect = 1.8
Identities = 30/134 (22%), Positives = 48/134 (35%), Gaps = 4/134 (2%)
Query: 657 TDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPP 716
T S S + +L + G+ + P P + + P+ Q P L+ P P
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAP 434
Query: 717 PPPESPPPPPPPPP-PAEDGEIQEVEMEDEGSEEPPA--PGTEEDTPLKPSAQTTVVTSQ 773
P ++P P P PA+ + + G +PP+ PG + P +P
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP 494
Query: 774 SSVDSTISSSSSTK 787
S STK
Sbjct: 495 GSAKPPSQQPGSTK 508
Score = 32.0 bits (71), Expect = 3.0
Identities = 61/311 (19%), Positives = 111/311 (35%), Gaps = 42/311 (13%)
Query: 691 PFWTLLQSNVPVLQPPLP-------LEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEME 743
P L+ S+ +P +P E PP +S P PP E +V
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE-----KVSPF 816
Query: 744 DEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQR 803
D + PA ++ + PS+++ Q VD K + + + + +
Sbjct: 817 DSKAIPRPASDSKIISHPGPSSESK---GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 804 SATIGSSPVLYSQSAIATGHQAAGIGNQAT----GIGHQT-IPVSLPAAGM--------G 850
+ P + + T Q+ Q+ +G T P S P G
Sbjct: 874 GSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
Query: 851 HQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPP 910
A S SN + A P S + P+ QP ++G PP
Sbjct: 934 FGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG------------PPK 981
Query: 911 PPP-PPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEED 969
PP PA +P ++TK +K + + P+ VK+ ++ ++ +D+ S + E
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT-VKRTETEKKPPPIKDSKSLTAEP 1040
Query: 970 RESTAQKRIEE 980
+++ ++E+
Sbjct: 1041 QKAVLPTKLEK 1051
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 57.8 bits (138), Expect = 5e-08
Identities = 61/256 (23%), Positives = 91/256 (35%), Gaps = 28/256 (10%)
Query: 708 PLEMPPPPPPPPESP----PPPPPPPPPAEDGEIQEVEMEDEGSEEPPA--PGTEEDT-- 759
P++ P P PP + P P P PPA+ + + + G+ +PP PGT +
Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364
Query: 760 ---PLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQ 816
P KP AQ T SS + + G+ + + + +G+ L Q
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
Query: 817 SAIATGHQAAGIGNQATGIGHQTIPVSLPAAGM--GHQARGMSLQSNYLGLAAAPAIMSY 874
G+ + A G PV P G QA + G P+ +
Sbjct: 425 P---------GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP- 474
Query: 875 AECSVPIGVTAPSLQPVQARG-AVPTATIIEPPPPPPPPPPPPPPAPKMP----PPEKTK 929
P P+ P Q G A P + PPP P P P+P+ P PP +
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Query: 930 KGRKDKAKKSKTKMPS 945
K A++ PS
Sbjct: 535 GSAKPSAQQPSPAKPS 550
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/54 (51%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPP 731
SG S SSL P P S++ + P P PPPPPPPP PPPPPP PPP
Sbjct: 2378 SGSPSVSSL-PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Score = 54.3 bits (129), Expect = 6e-07
Identities = 19/25 (76%), Positives = 20/25 (80%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKTK 929
PPPPPPPPPPPPPP P +PPP K
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPK 2434
Score = 53.5 bits (127), Expect = 1e-06
Identities = 23/50 (46%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 879 VPIGVTAPSLQPVQARGAVPTATI---IEPPPPPPPPPPPPPPAPKMPPP 925
+P G + S P + R ++++ +PPPPPPPPPPPPPP P PPP
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 51.6 bits (122), Expect = 4e-06
Identities = 18/21 (85%), Positives = 18/21 (85%)
Query: 905 PPPPPPPPPPPPPPAPKMPPP 925
PPPPPPPPPPPPPP P PPP
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPP 2426
Score = 48.5 bits (114), Expect = 3e-05
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 73/371 (19%)
Query: 679 GQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPP-------PPPPPPESPPPPPPPPPP 731
G+ S+ P P L P Q P P + PP PP P S PPP P P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
Query: 732 AEDGEIQEVEMEDEGSEEPPA-------PGTEEDTPLKPSA-QTTVVTSQSSVDSTISSS 783
A+ + GS +PP+ P ++ +P KPSA Q+T SQ+ +
Sbjct: 517 AKPSP------QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Query: 784 SSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVS 843
+ + K+ ++ + P+ + + + A N T QT S
Sbjct: 571 TVSPSAKQPPSQGLPKTI--------CPLCNTTELLLHVPEKA---NFNTCTECQTTVCS 619
Query: 844 L----PAAGMGHQARGMSL---QSNYLG--LAAAPAI----MSYAECSVPIGVTAPSLQP 890
L P + + L LG LA P+ + A + V+ S QP
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679
Query: 891 VQA---RGAVPTATIIEPPPPPPPPP---------------PPPPPAPKM----PPPEKT 928
Q + A P + + P P PPP PP A + PP E +
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739
Query: 929 KKGRKDKA--KKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQL 986
+DKA K K P +VK +L ++++ + S Q + EE L
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKP----TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 987 VSGMAERNANF 997
+ A+ + +F
Sbjct: 796 KTDSAKPSQSF 806
Score = 47.4 bits (111), Expect = 7e-05
Identities = 17/24 (70%), Positives = 18/24 (75%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKT 928
PPPPPPPPPPPPPP P P+ T
Sbjct: 2413 PPPPPPPPPPPPPPLPPPTSPKPT 2436
Score = 46.6 bits (109), Expect = 1e-04
Identities = 20/40 (50%), Positives = 21/40 (52%)
Query: 905 PPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMP 944
PPPPPPPPPPPP P P P P K + A T P
Sbjct: 2415 PPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 40.0 bits (92), Expect = 0.011
Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 15/137 (10%)
Query: 678 SGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEI 737
S +V S + PL+P L + VP + PLP ++ P P+ PP P A+
Sbjct: 3619 SPKVLYSPISPLSPGKALESAFVPY-EKPLPDDISPQKVLHPDMAKVPPASPKTAK---- 3673
Query: 738 QEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKR-----K 792
M+ S+ P T +++ P T T++ S T++SS + K +KR
Sbjct: 3674 ---MMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGS--QTMTSSGAQKKVKRTLPNPP 3728
Query: 793 ATEISTAVVQRSATIGS 809
EIST +T+G+
Sbjct: 3729 PEEISTGTQSTFSTMGT 3745
Score = 38.5 bits (88), Expect = 0.032
Identities = 18/41 (43%), Positives = 20/41 (48%)
Query: 887 SLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEK 927
S QP P PPPPPPP PPP P P + P +K
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKK 2442
Score = 38.1 bits (87), Expect = 0.042
Identities = 46/210 (21%), Positives = 70/210 (33%), Gaps = 20/210 (9%)
Query: 9 PGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASD 68
P + P Q P P PG P +P ST P QP P+ + T +
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGS--AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ 533
Query: 69 DSPSEDEQEAVQEVPRVVQNPPKPVMTTR-------PTAVKATGGLCLLGAYADSDDDDN 121
++ + Q KPV T PT + G N
Sbjct: 534 PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCN 593
Query: 122 DVSEKLAQSKETNGNQSTDIDSTLANF--------LAEID---AITAPQPAAPVGASAPP 170
L ++ N N T+ +T+ + L E+ + A G AP
Sbjct: 594 TTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV 653
Query: 171 PTPPRPEPKEAATSTLSSSTSNGTDSTQTS 200
P+ P+P+ K A +T S+ + + QTS
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683
Score = 35.0 bits (79), Expect = 0.36
Identities = 35/157 (22%), Positives = 52/157 (33%), Gaps = 8/157 (5%)
Query: 25 STPGRDPEPEPDTEPDSTAAV---PSQPAPSAATTTTTAVTAAAASDDSPSEDEQEAVQE 81
S P EP +E D P QP TT + ++A D PS Q +E
Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 82 --VPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQST 139
P + + KP + PT K + D+ + S E+ G +
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSP---FDSKAIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 140 DIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRP 176
D ++ A P+ +P P PRP
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Score = 32.7 bits (73), Expect = 1.8
Identities = 30/134 (22%), Positives = 48/134 (35%), Gaps = 4/134 (2%)
Query: 657 TDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPP 716
T S S + +L + G+ + P P + + P+ Q P L+ P P
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAP 434
Query: 717 PPPESPPPPPPPPP-PAEDGEIQEVEMEDEGSEEPPA--PGTEEDTPLKPSAQTTVVTSQ 773
P ++P P P PA+ + + G +PP+ PG + P +P
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP 494
Query: 774 SSVDSTISSSSSTK 787
S STK
Sbjct: 495 GSAKPPSQQPGSTK 508
Score = 32.0 bits (71), Expect = 3.0
Identities = 61/311 (19%), Positives = 111/311 (35%), Gaps = 42/311 (13%)
Query: 691 PFWTLLQSNVPVLQPPLP-------LEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEME 743
P L+ S+ +P +P E PP +S P PP E +V
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE-----KVSPF 816
Query: 744 DEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQR 803
D + PA ++ + PS+++ Q VD K + + + + +
Sbjct: 817 DSKAIPRPASDSKIISHPGPSSESK---GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 804 SATIGSSPVLYSQSAIATGHQAAGIGNQAT----GIGHQT-IPVSLPAAGM--------G 850
+ P + + T Q+ Q+ +G T P S P G
Sbjct: 874 GSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
Query: 851 HQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPP 910
A S SN + A P S + P+ QP ++G PP
Sbjct: 934 FGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG------------PPK 981
Query: 911 PPP-PPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEED 969
PP PA +P ++TK +K + + P+ VK+ ++ ++ +D+ S + E
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT-VKRTETEKKPPPIKDSKSLTAEP 1040
Query: 970 RESTAQKRIEE 980
+++ ++E+
Sbjct: 1041 QKAVLPTKLEK 1051
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 57.0 bits (136), Expect = 9e-08
Identities = 93/438 (21%), Positives = 147/438 (33%), Gaps = 87/438 (19%)
Query: 609 HRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTG------------ 656
HR+ F ++ + E+ E ++EE++ + +E+ D A T K +T
Sbjct: 955 HRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSS 1014
Query: 657 ----------------TDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNV 700
+DS S+ SS +S+ S S S SSS + +
Sbjct: 1015 SKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAAL 1074
Query: 701 PVLQPPLPLEMPPPPPPPPESPPP-----------------PPPPPPPAEDGEIQEVEME 743
P PP P E+P P P P E P P P P P E+
Sbjct: 1075 PSASPP-PREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRP 1133
Query: 744 DEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSS------------------- 784
E PPAP D +PS+ ++ T+S S+
Sbjct: 1134 PEPPAGPPAPAPRPDE--RPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKF 1191
Query: 785 ----STKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTI 840
S K + I + ++ + S P S+ G AG + T
Sbjct: 1192 PGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRG----GRSRAGGRGRLTEEEEAEP 1247
Query: 841 PVSLPAAGMGHQARGMSLQSNYLGLAAAPAI--MSYAECSVPIGVTAPSLQPVQARGAVP 898
+ A + ++L GL A PA+ E S P L +
Sbjct: 1248 GTEVDLAVLAD----LALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYA 1303
Query: 899 TATIIEPPPPP--PPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRE 956
A PP P PP P P P A P ++ + + +++ P +++ QRE
Sbjct: 1304 LAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQ----QRE 1359
Query: 957 LDEEDNSSSSEEDRESTA 974
EE+ EE+ E ++
Sbjct: 1360 EGEEEGEEEGEEEEEESS 1377
Score = 55.8 bits (133), Expect = 2e-07
Identities = 80/346 (23%), Positives = 116/346 (33%), Gaps = 66/346 (19%)
Query: 630 EEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLM-- 687
E +++ ++ + + A T + +T SS S+ SL S S SSSS
Sbjct: 302 ENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRS 361
Query: 688 -------------------------------PLTPFWTLLQSNVPVLQPPLPLEMPPPP- 715
P PF P P +PP P
Sbjct: 362 SDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFP---PSYTSYLPPEPS 418
Query: 716 --------PPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQT 767
PP E+PPP PP P G E E+ + PA +P +
Sbjct: 419 RPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNE 478
Query: 768 TVVTSQ-SSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAA 826
+V +Q SS+DS I + K T + + SS VL ++ TG +
Sbjct: 479 SVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEEN----SSMVLGARD---TGSEVP 531
Query: 827 GIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAP 886
+G GH P + P A + + +P + S
Sbjct: 532 ------SGSGHG--PCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDM 583
Query: 887 SLQPVQARGAVPTATII--EPPPPPPPPPPPPPPAPKMP---PPEK 927
+ G+ P A +PPPPPPPPPPPPP +P PP +
Sbjct: 584 EISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQ 629
Score = 46.2 bits (108), Expect = 2e-04
Identities = 21/42 (50%), Positives = 22/42 (52%)
Query: 688 PLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPP 729
P P+ L P QP L P PPPPE PPPPPPPP
Sbjct: 613 PPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPP 654
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/191 (23%), Positives = 63/191 (32%), Gaps = 58/191 (30%)
Query: 604 HWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAK--------------- 648
H D R + EQ + + D EEEEE S +T ++
Sbjct: 485 HSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPA 544
Query: 649 --------QTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNV 700
T + G S +++ + S C ++S P +
Sbjct: 545 PANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPP-----PAPT 599
Query: 701 PVLQPPLPLEMPPPPPPP-----------------------PESPP----PPPPPPPPAE 733
P QPP P PPPPPPP P+ PP PPPPPPPP
Sbjct: 600 PPQQPPPP---PPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHI 656
Query: 734 DGEIQEVEMED 744
+ +E+ D
Sbjct: 657 YDFVNSLELMD 667
Score = 40.0 bits (92), Expect = 0.011
Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 31/153 (20%)
Query: 30 DPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQEAVQEVPRVVQN- 88
D + E D+ DS ++ S + S++++++++ +++++S +S SEDE+E +E P + +
Sbjct: 1022 DSDGENDSTSDSESS--SSSSSSSSSSSSSSSSSSSSSSESSSEDEEE--EERPAALPSA 1077
Query: 89 --PPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLA 146
PP+ V P V+ V E++A G+ T + A
Sbjct: 1078 SPPPREVPVPTPAPVEV------------------PVPERVA------GSPVTPLPEQEA 1113
Query: 147 NFLAEIDAITAPQPAAPVGASAPPPTPPRPEPK 179
+ P+AP+ PP PP P P+
Sbjct: 1114 SPARPAGPTEESPPSAPLRPPEPPAGPPAPAPR 1146
Score = 39.7 bits (91), Expect = 0.015
Identities = 44/187 (23%), Positives = 74/187 (39%), Gaps = 39/187 (20%)
Query: 22 PRGSTPGRDPEPEPDTEPDSTAAVPSQPA------------------PSAATTTTTAVTA 63
PR STP + E +P+ E + A P +P S A + +
Sbjct: 912 PRPSTPAEEDEDDPEQEKE--AGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEAS 969
Query: 64 AAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATG--------GLCLLGAYAD 115
+S + ED++E ++ R + V TT+ + G C L YAD
Sbjct: 970 QESSSEKDEEDDEEDEEDEDR-----EEAVDTTKKETEVSDGEDEESDSSSKCSL--YAD 1022
Query: 116 SDDDDNDVSE----KLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPP 171
SD +++ S+ + S ++ + S+ S+ ++ + D +PAA AS PP
Sbjct: 1023 SDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPR 1082
Query: 172 TPPRPEP 178
P P P
Sbjct: 1083 EVPVPTP 1089
Score = 35.4 bits (80), Expect = 0.27
Identities = 32/139 (23%), Positives = 53/139 (38%), Gaps = 18/139 (12%)
Query: 383 SQEDLCSVVQSGESEEEEEQDTLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPAS 442
S+ + S S E +EE++++ E E E + E DG S S S A
Sbjct: 963 SEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYAD 1022
Query: 443 QDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKE 502
DG +STS S S + + + ++ + +S E+S ++
Sbjct: 1023 SDG------------------ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSED 1064
Query: 503 MEVEESPEKIKVQTTPKVE 521
E EE P + + P E
Sbjct: 1065 EEEEERPAALPSASPPPRE 1083
Score = 33.5 bits (75), Expect = 1.0
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 15/89 (16%)
Query: 636 SQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTL 695
++A+E + + L +Q + + + E E S+ S G + SL
Sbjct: 1344 AEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSL--------- 1394
Query: 696 LQSNVPVLQPPLPLEMPPPPPPPPESPPP 724
+S+ +PP PPPPPPPP + P
Sbjct: 1395 -RSHARRRRPP-----PPPPPPPPRAYEP 1417
Score = 33.1 bits (74), Expect = 1.4
Identities = 23/87 (26%), Positives = 33/87 (37%), Gaps = 11/87 (12%)
Query: 13 PILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPS 72
P L PP P P P P PD P S + P T + +A+ A + P+
Sbjct: 1127 PSAPLRPPEPPAGPPA--PAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPA 1184
Query: 73 EDEQ---------EAVQEVPRVVQNPP 90
Q +A + V R ++N P
Sbjct: 1185 TPPQAKFPGPASRKAPRGVERTIRNLP 1211
Score = 32.7 bits (73), Expect = 1.8
Identities = 12/18 (66%), Positives = 12/18 (66%)
Query: 909 PPPPPPPPPPAPKMPPPE 926
PPPPPPPPPP P E
Sbjct: 1403 PPPPPPPPPPRAYEPRSE 1420
Score = 32.3 bits (72), Expect = 2.3
Identities = 11/16 (68%), Positives = 12/16 (75%)
Query: 906 PPPPPPPPPPPPPAPK 921
PPPPPPPPPP P+
Sbjct: 1403 PPPPPPPPPPRAYEPR 1418
Score = 31.6 bits (70), Expect = 4.0
Identities = 46/201 (22%), Positives = 76/201 (37%), Gaps = 19/201 (9%)
Query: 747 SEEPPAPGTEEDTPLK------PSAQTTVVTSQSSV----DSTISSSSSTKGIKRKATEI 796
S++ + +DTP S+Q T TS+ S DS SSS+++ K + +E
Sbjct: 244 SQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSEN 303
Query: 797 S--TAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQAR 854
S A +R + S+ S + AT A ++ + + S ++ ++
Sbjct: 304 SYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQ-FRSS 362
Query: 855 GMSLQSNYLGLAAAPAIMSY----AECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPP 910
+ + Y SY A P G AP + R + + P P P
Sbjct: 363 DANYPAYYESWNRYQRHTSYPPRRATREEPPG--APFAENTAERFPPSYTSYLPPEPSRP 420
Query: 911 PPPPPPPPAPKMPPPEKTKKG 931
PPA + PPPE + G
Sbjct: 421 TDQDYRPPASEAPPPEPPEPG 441
Score = 31.6 bits (70), Expect = 4.0
Identities = 10/10 (100%), Positives = 10/10 (100%)
Query: 722 PPPPPPPPPP 731
PPPPPPPPPP
Sbjct: 1403 PPPPPPPPPP 1412
Score = 31.6 bits (70), Expect = 4.0
Identities = 10/10 (100%), Positives = 10/10 (100%)
Query: 905 PPPPPPPPPP 914
PPPPPPPPPP
Sbjct: 1403 PPPPPPPPPP 1412
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 57.0 bits (136), Expect = 9e-08
Identities = 23/36 (63%), Positives = 26/36 (72%), Gaps = 2/36 (5%)
Query: 703 LQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQ 738
LQ P P PPPPPPPP PPPPPPPPPP+ ++Q
Sbjct: 1990 LQAPPPT--PPPPPPPPPPPPPPPPPPPPSAPPQVQ 2023
Score = 56.2 bits (134), Expect = 2e-07
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 10/133 (7%)
Query: 842 VSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGV------TAPSLQPVQARG 895
+SLP A G L G ++ P + P G T+ + P +
Sbjct: 3047 ISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLS 3106
Query: 896 AVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQR 955
+ PT +++ PPPPPPPPPPPP + ++T++ K+ KK +TK P+ VKK + +
Sbjct: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSL--SGQQTEQQNKESEKK-QTK-PNKVKKIKEEEL 3162
Query: 956 ELDEEDNSSSSEE 968
E + + EE
Sbjct: 3163 EATKPEKHPKKEE 3175
Score = 54.3 bits (129), Expect = 6e-07
Identities = 26/47 (55%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 688 PLTPFWTLLQSNVPVLQP---PLPLEMPPPPPPPPESPPPPPPPPPP 731
PL P S PV P PL+ PPP PPPP PPPPPPPPPP
Sbjct: 1966 PLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPP 2012
Score = 53.9 bits (128), Expect = 7e-07
Identities = 22/39 (56%), Positives = 24/39 (61%)
Query: 887 SLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPP 925
S+ PV+ V T PP PPPPPPPPPPP P PPP
Sbjct: 1976 SMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014
Score = 52.4 bits (124), Expect = 2e-06
Identities = 23/47 (48%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
Query: 880 PIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPE 926
P+ + P+QA P T PPPPPPPPPPPPPP P PP+
Sbjct: 1979 PVKIPNTVSTPLQA----PPPTPPPPPPPPPPPPPPPPPPPPSAPPQ 2021
Score = 46.2 bits (108), Expect = 2e-04
Identities = 40/144 (27%), Positives = 58/144 (40%), Gaps = 24/144 (16%)
Query: 705 PPLPLEMPPPPP---PPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPL 761
P L L P P PP PPPPPPPPPP+ Q+ E +++ SE+ +
Sbjct: 3101 PALSLSSAPTKPLLQTPP--PPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIK 3158
Query: 762 KPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIAT 821
+ + T + ISS+ S G T + +Q Q+AIA
Sbjct: 3159 EEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQLQA-----------LQNAIA- 3206
Query: 822 GHQAAGIGNQATGIGHQTIPVSLP 845
G+ A+ IG Q +P +P
Sbjct: 3207 -------GDPASFIGGQFLPYFIP 3223
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
Query: 867 AAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPP 925
A P S +P V+ P P P PPPPPPPPPPPP P++ P
Sbjct: 1970 APPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP---PPPPPPPPPPPPSAPPQVQLP 2025
Score = 41.6 bits (96), Expect = 0.004
Identities = 19/58 (32%), Positives = 24/58 (41%)
Query: 706 PLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKP 763
P+ P PPPPP PP PP PP P+ G ++ + PP P P
Sbjct: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/91 (29%), Positives = 30/91 (32%), Gaps = 42/91 (46%)
Query: 703 LQPPLPLEMPPPPPPPP------------------------ESPPPPPPPPPPAEDGEIQ 738
+ P P PPPPPPPP ++PPP PPPPPP
Sbjct: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP------- 2002
Query: 739 EVEMEDEGSEEPPAPGTEEDTPLKPSAQTTV 769
PP P P PSA V
Sbjct: 2003 -----------PPPPPPPPPPPPPPSAPPQV 2022
Score = 40.8 bits (94), Expect = 0.007
Identities = 16/30 (53%), Positives = 18/30 (60%)
Query: 898 PTATIIEPPPPPPPPPPPPPPAPKMPPPEK 927
P++ PPPPPPPP PP PP P P K
Sbjct: 1952 PSSPETPPPPPPPPPLPPAPPQPSSMGPVK 1981
Score = 38.9 bits (89), Expect = 0.025
Identities = 16/40 (40%), Positives = 19/40 (47%)
Query: 886 PSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPP 925
P+ + G V + P PPP PPPPP P PPP
Sbjct: 1969 PAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
Score = 37.0 bits (84), Expect = 0.094
Identities = 17/40 (42%), Positives = 19/40 (47%)
Query: 892 QARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKG 931
Q R A I P P PPPPPPPP PP+ + G
Sbjct: 1939 QYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMG 1978
Score = 33.5 bits (75), Expect = 1.0
Identities = 33/142 (23%), Positives = 55/142 (38%), Gaps = 6/142 (4%)
Query: 648 KQTLKDKT--GTDSNSTESSETSTGSLCKE--SFSGQVSSSSLMPLTPFWTLLQSNVPVL 703
KQ KD+ D + TE S +T + + + SGQ ++ + ++ P++
Sbjct: 2288 KQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLI 2347
Query: 704 QPPLP-LEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLK 762
P P E P P P P P PP++ G + + S+ P A + +
Sbjct: 2348 PSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ-GTKPALPLASTSSDPPQASTAQPQPQPQ 2406
Query: 763 PSAQTTVVTSQSSVDSTISSSS 784
P Q ++ S T SS
Sbjct: 2407 PPKQPQLIGRPPSASQTPVPSS 2428
Score = 33.1 bits (74), Expect = 1.4
Identities = 17/48 (35%), Positives = 17/48 (35%), Gaps = 27/48 (56%)
Query: 905 PPPPPP---------------------------PPPPPPPPAPKMPPP 925
PPP PP PPPPPPPP P PPP
Sbjct: 1964 PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPP 2011
Score = 32.0 bits (71), Expect = 3.0
Identities = 24/94 (25%), Positives = 34/94 (36%), Gaps = 10/94 (10%)
Query: 18 SPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPA-------PSAATTTTTAVTAAAASDDS 70
+P GS P P EP+ T+ P PA PS + T A++
Sbjct: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSD 2392
Query: 71 PSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKAT 104
P + Q P Q P +P + RP + T
Sbjct: 2393 PPQASTAQPQPQP---QPPKQPQLIGRPPSASQT 2423
Score = 31.2 bits (69), Expect = 5.2
Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 5/53 (9%)
Query: 878 SVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPP-----PPPAPKMPPP 925
S P T P+L P A+ +P P P PP P PP A + P P
Sbjct: 2374 SPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVP 2426
Score = 30.4 bits (67), Expect = 8.8
Identities = 26/109 (23%), Positives = 43/109 (39%), Gaps = 5/109 (4%)
Query: 886 PSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPS 945
PS + A+P A+ PP P P P PP + GR A ++
Sbjct: 2373 PSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQ---PPKQPQLIGRPPSASQTPVPSSP 2429
Query: 946 LVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERN 994
L S+Q L + + D+ + A +E W++ Q + +A +N
Sbjct: 2430 LQISMTSLQNSLPPQ--LLQYQCDQCTVAFPTLELWQEHQHMHFLAAQN 2476
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 57.0 bits (136), Expect = 9e-08
Identities = 58/223 (26%), Positives = 86/223 (38%), Gaps = 33/223 (14%)
Query: 705 PPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEG--------SEEPPAPGTE 756
PPLP E PP PP P PP PP PP E E + E +E P +P E
Sbjct: 1147 PPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEE 1206
Query: 757 EDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQ 816
+ +P + ++ S+V + S S A++ S V + + T+ P
Sbjct: 1207 SVSQPEPPVSQSEISEPSAVPTDYSVS---------ASDPSVLVSEAAVTVPEPPPEPES 1257
Query: 817 SAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMS-YA 875
S T ++A + + H+ +P P M + MS + LA+ P +MS A
Sbjct: 1258 SITLTPVESAVVAEE-----HEVVP-ERPVTCMVSETPAMSAEPTV--LASEPPVMSETA 1309
Query: 876 ECSVPIGVTAPSLQPVQARGAVPTAT-------IIEPPPPPPP 911
E + + V VP T I+EPP P
Sbjct: 1310 ETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAP 1352
Score = 35.4 bits (80), Expect = 0.27
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 3/74 (4%)
Query: 897 VPTATIIEPPPPPPPPPPPPPPAPKMP---PPEKTKKGRKDKAKKSKTKMPSLVKKWQSI 953
VP EPP PP PP PP P +P PPE + A ++ P+ V S
Sbjct: 1146 VPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSE 1205
Query: 954 QRELDEEDNSSSSE 967
+ E S SE
Sbjct: 1206 ESVSQPEPPVSQSE 1219
Score = 34.7 bits (78), Expect = 0.47
Identities = 52/251 (20%), Positives = 85/251 (33%), Gaps = 39/251 (15%)
Query: 701 PVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTP 760
PVL+ P P P P P P S P P P PPA E G P P ++ P
Sbjct: 401 PVLELPGPSATPVPELPGPLSTPVPELPGPPA------TAVPELPGPSVTPVPQLSQELP 454
Query: 761 LKPSAQTTVVTSQSSVDSTISS---------SSSTKGIKRKATEISTAVVQRSATIGSSP 811
P+ + Q + + + +++ + ++ A ++ + ++ T
Sbjct: 455 GLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPVTTTELE 514
Query: 812 VLYSQSAIA-TGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPA 870
+ + GH G T+ + LP + A + Q + G+ P
Sbjct: 515 QPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPG 574
Query: 871 IMSYAEC----SVPIGVTAPSLQ-PVQARGAV-----------------PTAT-IIEPPP 907
+ S P+ A L P+ A GA+ P AT ++E P
Sbjct: 575 LPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPG 634
Query: 908 PPPPPPPPPPP 918
P P P P
Sbjct: 635 QPGAPELPGQP 645
Score = 33.9 bits (76), Expect = 0.80
Identities = 65/300 (21%), Positives = 105/300 (35%), Gaps = 44/300 (14%)
Query: 649 QTLKDKTGTDSNS-------TESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVP 701
+TLK T T S +E SE S + + S + + S + P+ +L+S+ P
Sbjct: 203 ETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEP 262
Query: 702 VLQPPLPLEMPPPPPPPPESPPPP-------PPPPPPAEDGEIQEVEMEDEGSEEP-PAP 753
V+ + +M + P P PP E E V E P P+
Sbjct: 263 VVTMSVEYQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPST 322
Query: 754 GTEEDTPLKPSAQTTVVTSQS-SVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPV 812
T D P + + + Q V S I+ SS T+ + +TA+ + +++ S+
Sbjct: 323 STTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAME 382
Query: 813 LYSQSAIA----TGHQAAGI----GNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLG 864
L A + G + G AT + P+S P +
Sbjct: 383 LPGPPATSMPELQGPPVTPVLELPGPSATPVPELPGPLSTPVPEL--------------- 427
Query: 865 LAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATI-IEPPPPPPPPPPPPPPAPKMP 923
P + E P P L Q +P ++ +EPP P PP P +P
Sbjct: 428 --PGPPATAVPELPGPSVTPVPQLS--QELPGLPAPSMGLEPPQEVPEPPVMAQELPGLP 483
Score = 32.3 bits (72), Expect = 2.3
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 8/79 (10%)
Query: 851 HQARGMSLQSNY------LGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIE 904
+ A S+ S+Y + +AA SY + + P P + +P E
Sbjct: 1107 YSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPL--PPEEPPTMPPLPPEE 1164
Query: 905 PPPPPPPPPPPPPPAPKMP 923
PP PP PP PP P +P
Sbjct: 1165 PPMTPPLPPEEPPEGPALP 1183
Score = 31.6 bits (70), Expect = 4.0
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 6/85 (7%)
Query: 899 TATIIEPPPPPPPP---PPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQR 955
T + PP PP P PP PP P M PP ++ + A ++ + W +
Sbjct: 1141 TEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPT--- 1197
Query: 956 ELDEEDNSSSSEEDRESTAQKRIEE 980
E+ + S + +Q I E
Sbjct: 1198 EVPSSPSEESVSQPEPPVSQSEISE 1222
Score = 31.6 bits (70), Expect = 4.0
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 16/122 (13%)
Query: 727 PPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSST 786
P PP + + + + + EP P E P Q +++ S+ SV S ST
Sbjct: 1392 PEPPVVAEPDYVTIPVPVVSALEPSVPVLE---PAVSVLQPSMIVSEPSV----SVQEST 1444
Query: 787 KGIKRKATEIS--TAVVQRSATIGSSPVLYSQSAIATGHQAAGIG------NQATGIGHQ 838
+ A +S T V+ I S+P++ +S+I + H GI N A IG Q
Sbjct: 1445 VTVSEPAVTVSEQTQVIPTEVAIESTPMIL-ESSIMSSHVMKGINLSSGDQNLAPEIGMQ 1503
Query: 839 TI 840
I
Sbjct: 1504 EI 1505
Score = 31.2 bits (69), Expect = 5.2
Identities = 38/185 (20%), Positives = 70/185 (37%), Gaps = 11/185 (5%)
Query: 19 PPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQE- 77
P P + + P +E +AVP+ + SA+ + AA + P E E
Sbjct: 1200 PSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSI 1259
Query: 78 AVQEVPRVVQNPPKPVMTTRPTA--VKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNG 135
+ V V V+ RP V T + S+ + + S +G
Sbjct: 1260 TLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAETFDSMRASG 1319
Query: 136 NQSTDIDSTLANFLAEIDAITAPQPAAPV---GASAPPPTPPRPEPKEAATSTLSSSTSN 192
+ ++++ ++L + A+T P A + A A P + + +A + L SST
Sbjct: 1320 HVASEVSTSLL-----VPAVTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVT 1374
Query: 193 GTDST 197
+S+
Sbjct: 1375 VLESS 1379
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.123 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,053,220
Number of Sequences: 37866
Number of extensions: 3572209
Number of successful extensions: 132094
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1349
Number of HSP's successfully gapped in prelim test: 1421
Number of HSP's that attempted gapping in prelim test: 36558
Number of HSP's gapped (non-prelim): 49357
length of query: 1017
length of database: 18,247,518
effective HSP length: 112
effective length of query: 905
effective length of database: 14,006,526
effective search space: 12675906030
effective search space used: 12675906030
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.