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Search of human proteins with 15812198
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15812198 F-box only protein 2 [Homo sapiens]
(296 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15812198 F-box only protein 2 [Homo sapiens] 625 e-179
gi|8922188 F-box only protein 6 [Homo sapiens] 264 8e-71
gi|34878735 F-box protein 44 isoform 1 [Homo sapiens] 256 2e-68
gi|62388868 F-box protein 44 isoform 1 [Homo sapiens] 256 2e-68
gi|30520327 F-box protein 27 [Homo sapiens] 191 7e-49
gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens] 181 5e-46
gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens] 181 5e-46
gi|34878749 F-box protein 44 isoform 2 [Homo sapiens] 108 6e-24
gi|34878753 F-box protein 44 isoform 2 [Homo sapiens] 108 6e-24
gi|47825361 non-specific cytotoxic cell receptor protein 1 homol... 100 3e-21
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 48 1e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 40 0.002
gi|83035136 F-box protein 31 [Homo sapiens] 40 0.003
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 39 0.004
gi|27312027 F-box only protein 16 [Homo sapiens] 39 0.007
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 38 0.009
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 38 0.009
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 38 0.009
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 38 0.012
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 38 0.012
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 38 0.012
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 37 0.016
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 37 0.016
gi|128485503 kelch-like 30 [Homo sapiens] 37 0.016
gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens] 37 0.021
gi|110349786 Alstrom syndrome 1 [Homo sapiens] 37 0.027
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 37 0.027
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 36 0.035
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 36 0.035
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 36 0.035
>gi|15812198 F-box only protein 2 [Homo sapiens]
Length = 296
Score = 625 bits (1611), Expect = e-179
Identities = 296/296 (100%), Positives = 296/296 (100%)
Query: 1 MDGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLA 60
MDGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLA
Sbjct: 1 MDGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLA 60
Query: 61 ALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRR 120
ALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRR
Sbjct: 61 ALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRR 120
Query: 121 RNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQ 180
RNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQ
Sbjct: 121 RNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQ 180
Query: 181 VIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVA 240
VIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVA
Sbjct: 181 VIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVA 240
Query: 241 VPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP 296
VPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
Sbjct: 241 VPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP 296
>gi|8922188 F-box only protein 6 [Homo sapiens]
Length = 293
Score = 264 bits (674), Expect = 8e-71
Identities = 128/255 (50%), Positives = 170/255 (66%), Gaps = 3/255 (1%)
Query: 42 AAAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEG 101
AA ++ELPE +LL + +PA +L+ CRLVC W++L+D LW KC +EG + +
Sbjct: 8 AALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKD 67
Query: 102 GVEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTH 161
+ D W+ FYFL RNLLRNPC EED+ W +GGD W+VE LPG G +F
Sbjct: 68 WDQPVAD-WKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFP- 125
Query: 162 DESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTV 221
D VKKYF +S+E C K+Q++DL AEGYWEELLDT +P IVVKDW++ R+D GC Y+L V
Sbjct: 126 DPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKV 185
Query: 222 KLLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKG 281
+L S VLA F V + Q + W E+S+TF+DY GVR++ F+HGG+D+ YW G
Sbjct: 186 QLASADYFVLASFEPPPVTI-QQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAG 244
Query: 282 WFGARVTNSSVWVEP 296
W+G RVTNSS+ V P
Sbjct: 245 WYGPRVTNSSIVVSP 259
>gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]
Length = 255
Score = 256 bits (654), Expect = 2e-68
Identities = 124/254 (48%), Positives = 165/254 (64%), Gaps = 3/254 (1%)
Query: 43 AAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102
A ++ELPE +LL + +PA +L+ CRLVC W++L+D LW KC +EG + E
Sbjct: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
Query: 103 VEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHD 162
+ D W+ FYFL RNLL NPC EE E W +GGD W+VE+L D EF +D
Sbjct: 62 DQPVAD-WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 163 ESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVK 222
+ VKKYF +S+ C K+QV+DL+AEGYWEEL+DTT+P I VKDW++ R D G Y+L V+
Sbjct: 121 Q-VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQ 179
Query: 223 LLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGW 282
LLS L F + Q SD W E+SHTF++Y PGVR++ F+HGG D+ YW GW
Sbjct: 180 LLSSAHAPLGTFQPDPATIQQKSD-AKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGW 238
Query: 283 FGARVTNSSVWVEP 296
+G RVTNSS+ + P
Sbjct: 239 YGPRVTNSSITIGP 252
>gi|62388868 F-box protein 44 isoform 1 [Homo sapiens]
Length = 255
Score = 256 bits (654), Expect = 2e-68
Identities = 124/254 (48%), Positives = 165/254 (64%), Gaps = 3/254 (1%)
Query: 43 AAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102
A ++ELPE +LL + +PA +L+ CRLVC W++L+D LW KC +EG + E
Sbjct: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
Query: 103 VEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHD 162
+ D W+ FYFL RNLL NPC EE E W +GGD W+VE+L D EF +D
Sbjct: 62 DQPVAD-WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 163 ESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVK 222
+ VKKYF +S+ C K+QV+DL+AEGYWEEL+DTT+P I VKDW++ R D G Y+L V+
Sbjct: 121 Q-VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQ 179
Query: 223 LLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGW 282
LLS L F + Q SD W E+SHTF++Y PGVR++ F+HGG D+ YW GW
Sbjct: 180 LLSSAHAPLGTFQPDPATIQQKSD-AKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGW 238
Query: 283 FGARVTNSSVWVEP 296
+G RVTNSS+ + P
Sbjct: 239 YGPRVTNSSITIGP 252
>gi|30520327 F-box protein 27 [Homo sapiens]
Length = 283
Score = 191 bits (485), Expect = 7e-49
Identities = 117/285 (41%), Positives = 156/285 (54%), Gaps = 32/285 (11%)
Query: 26 SAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGA 85
+A PE + EE A L +LP LLL VL+ +P L+ CR VC W+ LVDG
Sbjct: 10 AARVPAPEPEPEE-----ALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRALVDGQ 64
Query: 86 PLWLL-KCQQEGLVPEGGVEEERDHWQQFY---------FLSKRR--RNLLRNPCGEEDL 133
LWLL + G + R F ++R RNL+RNPCG+E L
Sbjct: 65 ALWLLILARDHGATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCGQEGL 124
Query: 134 EGWCDVEHGGDGWRVEE----LPGDSGVEFTHDESVKKYFASSFEWCRKAQVIDLQAEGY 189
W V+HGGDGW VEE +PG + F +SF WC K QV+DL+ EG
Sbjct: 125 RKWM-VQHGGDGWVVEENRTTVPGAPS---------QTCFVTSFSWCCKKQVLDLEEEGL 174
Query: 190 WEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGG 249
W ELLD+ + I V DW+ R D+GC+Y L V+LL ++ VL +FS+ +PQ +
Sbjct: 175 WPELLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQ-WNNNA 233
Query: 250 WMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWV 294
+ ++H F++ GVRFV FEH GQD+ +W G +GARVTNSSV V
Sbjct: 234 CLHVTHVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIV 278
>gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens]
Length = 287
Score = 181 bits (460), Expect = 5e-46
Identities = 100/267 (37%), Positives = 152/267 (56%), Gaps = 30/267 (11%)
Query: 47 LDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGV--- 103
LD LP LL++VL+ +P LV CR VC W+++VDG +WLL+ ++ +
Sbjct: 27 LDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAV 86
Query: 104 -------EEERDHWQ-----QFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEE- 150
E+++ + ++ + RNL+ N CGE+ GW +VEHGG+GW +E+
Sbjct: 87 AQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGW-EVEHGGNGWAIEKN 145
Query: 151 ---LPGDSGVEFTHDESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWY 207
+PG + F +SFEWC K Q++DL EG W+ELLD+ Q I V DW+
Sbjct: 146 LTPVPGAPS---------QTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWW 196
Query: 208 SGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFV 267
R + GC+Y+L V+LL +E + +FS+ V Q ++ G ++SH FT++G G+R+V
Sbjct: 197 GARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTE-RGCRQVSHVFTNFGKGIRYV 255
Query: 268 RFEHGGQDSVYWKGWFGARVTNSSVWV 294
FE G+D W G +GA VT+SSV V
Sbjct: 256 SFEQYGRDVSSWVGHYGALVTHSSVRV 282
>gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens]
Length = 278
Score = 181 bits (460), Expect = 5e-46
Identities = 100/267 (37%), Positives = 152/267 (56%), Gaps = 30/267 (11%)
Query: 47 LDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGV--- 103
LD LP LL++VL+ +P LV CR VC W+++VDG +WLL+ ++ +
Sbjct: 18 LDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAV 77
Query: 104 -------EEERDHWQ-----QFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEE- 150
E+++ + ++ + RNL+ N CGE+ GW +VEHGG+GW +E+
Sbjct: 78 AQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGW-EVEHGGNGWAIEKN 136
Query: 151 ---LPGDSGVEFTHDESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWY 207
+PG + F +SFEWC K Q++DL EG W+ELLD+ Q I V DW+
Sbjct: 137 LTPVPGAPS---------QTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWW 187
Query: 208 SGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFV 267
R + GC+Y+L V+LL +E + +FS+ V Q ++ G ++SH FT++G G+R+V
Sbjct: 188 GARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTE-RGCRQVSHVFTNFGKGIRYV 246
Query: 268 RFEHGGQDSVYWKGWFGARVTNSSVWV 294
FE G+D W G +GA VT+SSV V
Sbjct: 247 SFEQYGRDVSSWVGHYGALVTHSSVRV 273
>gi|34878749 F-box protein 44 isoform 2 [Homo sapiens]
Length = 224
Score = 108 bits (270), Expect = 6e-24
Identities = 53/121 (43%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Query: 43 AAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102
A ++ELPE +LL + +PA +L+ CRLVC W++L+D LW KC +EG + E
Sbjct: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
Query: 103 VEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHD 162
+ D W+ FYFL RNLL NPC EE E W +GGD W+VE+L D EF +D
Sbjct: 62 DQPVAD-WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 163 E 163
+
Sbjct: 121 Q 121
>gi|34878753 F-box protein 44 isoform 2 [Homo sapiens]
Length = 224
Score = 108 bits (270), Expect = 6e-24
Identities = 53/121 (43%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Query: 43 AAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102
A ++ELPE +LL + +PA +L+ CRLVC W++L+D LW KC +EG + E
Sbjct: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
Query: 103 VEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHD 162
+ D W+ FYFL RNLL NPC EE E W +GGD W+VE+L D EF +D
Sbjct: 62 DQPVAD-WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 163 E 163
+
Sbjct: 121 Q 121
>gi|47825361 non-specific cytotoxic cell receptor protein 1 homolog
[Homo sapiens]
Length = 275
Score = 99.8 bits (247), Expect = 3e-21
Identities = 94/302 (31%), Positives = 129/302 (42%), Gaps = 50/302 (16%)
Query: 1 MDGDGDPESVGQ----PEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLL 56
M+ DG P S+ + P SP P + P + AA ELPEP
Sbjct: 14 MEADG-PASLQELPPSPRSPSPPPSPPPLPSPPSLP--------SPAAPEAPELPEP--- 61
Query: 57 RVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFL 116
A P+ A +L+ W L G L +R W+
Sbjct: 62 ----AQPSE--AHARQLLLEEWGPLSGGLEL-----------------PQRLTWKLLLLR 98
Query: 117 SKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWC 176
RNLLR+P E + + G R E G+ + E +++ + W
Sbjct: 99 RPLYRNLLRSP-NPEGINIYEPAPPTGPTQRPLETLGNFRGWYIRTEKLQQ----NQSWT 153
Query: 177 RKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLL-SEHENVLAEFS 235
K Q +DL AEG WEELLD QPAI V DW+ C+YEL V LL ++ V+A+
Sbjct: 154 VKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDACVYELHVWLLAADRRTVIAQH- 212
Query: 236 SGQVAVPQDSDG--GGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVW 293
VA G G W+++SH F YGPGVRF+ F H ++ + G RVT+SSV
Sbjct: 213 --HVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDSSVS 270
Query: 294 VE 295
V+
Sbjct: 271 VQ 272
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
sapiens]
Length = 532
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 8 ESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLD-ELPEPLLLRVLAALPAAE 66
E + Q + +PE A RPE++ + + D +LP L + + L E
Sbjct: 15 EELAQAQAPKKRRRPEAAERRARRPENEMND-----VPFFDIQLPYELAINIFQYLDRKE 69
Query: 67 LVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRRRNLLR 125
L + C V WK + + LW CQQEG +P+ + + W+ + + + ++LR
Sbjct: 70 LGR-CAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSI-SDYSCWKLIFQECRAKEHMLR 126
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/48 (43%), Positives = 28/48 (58%)
Query: 6 DPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEP 53
+ E + EE EE+ EE EEE E+++EEE AAAA L E+ P
Sbjct: 737 EEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGP 784
Score = 37.4 bits (85), Expect = 0.016
Identities = 18/40 (45%), Positives = 24/40 (60%)
Query: 6 DPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAA 45
+ E + EE EE+ EE EEE E+++EEE AAAA
Sbjct: 736 EEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA 775
Score = 32.3 bits (72), Expect = 0.51
Identities = 14/28 (50%), Positives = 18/28 (64%)
Query: 12 QPEEASPEEQPEEASAEEERPEDQQEEE 39
QP+ EE+ EE EEE ED++EEE
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEE 753
>gi|83035136 F-box protein 31 [Homo sapiens]
Length = 539
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 18/91 (19%)
Query: 22 PEEASAEEERPEDQQEEEAAAAAA-----------------YLDELPEPLLLRVLAALPA 64
P E +A + P+ EEE A+A L ELP LL+ + A+LP
Sbjct: 25 PAETAAADSEPDTDPEEERIEASAGVGGGLCAGPSPPPPRCSLLELPPELLVEIFASLPG 84
Query: 65 AELVQACRLVCLRWKELVDGAPLWLLKCQQE 95
+L + VC +++ ++ +W +C++E
Sbjct: 85 TDLPSLAQ-VCTKFRRILHTDTIWRRRCREE 114
>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
sapiens]
Length = 326
Score = 39.3 bits (90), Expect = 0.004
Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 45 AYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLW 88
A L ELP+ +LL + + LP + ++ R VC RWK LVD LW
Sbjct: 2 ATLVELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLW 44
>gi|27312027 F-box only protein 16 [Homo sapiens]
Length = 292
Score = 38.5 bits (88), Expect = 0.007
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 36 QEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKC 92
QE+ A A + +LP L L + + L L + C VC WK L + LW+LKC
Sbjct: 78 QEKIPAEALDFTTKLPRVLSLYIFSFLDPRSLCR-CAQVCWHWKNLAELDQLWMLKC 133
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 38.1 bits (87), Expect = 0.009
Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
Query: 6 DPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAA 65
D E G+ E+ +E+ EE +A+E+ E+++EEEAA +E E LL++ LP +
Sbjct: 1879 DEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK--EEGLEEGLLQM--KLPES 1934
Query: 66 ELVQACRLV 74
+Q C L+
Sbjct: 1935 VKLQMCHLL 1943
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 38.1 bits (87), Expect = 0.009
Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
Query: 6 DPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAA 65
D E G+ E+ +E+ EE +A+E+ E+++EEEAA +E E LL++ LP +
Sbjct: 1879 DEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK--EEGLEEGLLQM--KLPES 1934
Query: 66 ELVQACRLV 74
+Q C L+
Sbjct: 1935 VKLQMCHLL 1943
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 38.1 bits (87), Expect = 0.009
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Query: 49 ELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERD 108
+LP L + + L EL + C V WK + + LW CQQEG +P+ + +
Sbjct: 118 QLPYELAINIFQYLDRKELGR-CAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSI-SDYS 175
Query: 109 HWQQFYFLSKRRRNLLR 125
W+ + + + ++LR
Sbjct: 176 CWKLIFQECRAKEHMLR 192
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 37.7 bits (86), Expect = 0.012
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 46 YLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGL 97
++ LP+ L L VL+ L +L+QA + C W+ L + LW KC++EG+
Sbjct: 162 FISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEGI 212
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 37.7 bits (86), Expect = 0.012
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 46 YLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGL 97
++ LP+ L L VL+ L +L+QA + C W+ L + LW KC++EG+
Sbjct: 280 FISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEGI 330
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 37.7 bits (86), Expect = 0.012
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 46 YLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGL 97
++ LP+ L L VL+ L +L+QA + C W+ L + LW KC++EG+
Sbjct: 200 FISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEGI 250
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 37.4 bits (85), Expect = 0.016
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 2 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEE 39
DGD E V EE + EE+ EE + EEE E+++EEE
Sbjct: 448 DGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEE 485
Score = 31.6 bits (70), Expect = 0.87
Identities = 14/36 (38%), Positives = 22/36 (61%)
Query: 4 DGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEE 39
+G+ + VG + S + +P E AEEE E++ EEE
Sbjct: 440 EGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEE 475
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 37.4 bits (85), Expect = 0.016
Identities = 17/38 (44%), Positives = 23/38 (60%)
Query: 2 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEE 39
D D + E G+ EE EE+ EE EEE E+++EEE
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 32.3 bits (72), Expect = 0.51
Identities = 14/41 (34%), Positives = 23/41 (56%)
Query: 2 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAA 42
+G+ + E + EE EE+ EE EEE P+ + + E +A
Sbjct: 368 EGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSA 408
Score = 30.4 bits (67), Expect = 1.9
Identities = 13/38 (34%), Positives = 22/38 (57%)
Query: 2 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEE 39
D + + E + EEA EE+ +E EEE E+++E +
Sbjct: 362 DEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQ 399
Score = 30.0 bits (66), Expect = 2.5
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 6 DPESVGQPEEASPEEQPEEASAEEERPEDQQEEE 39
D E + EE EE+ E EE+ E+++EEE
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEE 392
Score = 28.1 bits (61), Expect = 9.7
Identities = 14/44 (31%), Positives = 21/44 (47%)
Query: 9 SVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPE 52
S+ E+ EE+ EE E E E++ EEE +E P+
Sbjct: 356 SLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQ 399
>gi|128485503 kelch-like 30 [Homo sapiens]
Length = 560
Score = 37.4 bits (85), Expect = 0.016
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 12/95 (12%)
Query: 21 QPEEASAEEERPEDQQEEEAAAA-------AAYLDELPEPLLLRVLAALPAAELVQACRL 73
QPE++ E + + +A AA +LD +P P + ++LA+ P + +ACR
Sbjct: 173 QPEQSRLEALMRWVRHDPQARAAHLPELLSLVHLDAVPRPCVQQLLASEPLIQESEACRA 232
Query: 74 VCLRWKELVDGAPLWLLKCQQEGLVPEGG--VEEE 106
+ DGAPL L + +E LV GG +EEE
Sbjct: 233 ALSQGH---DGAPLALQQKLEEVLVVVGGQALEEE 264
>gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens]
Length = 458
Score = 37.0 bits (84), Expect = 0.021
Identities = 32/128 (25%), Positives = 49/128 (38%), Gaps = 19/128 (14%)
Query: 2 DGDGDPESVGQPEEA---------SPEE------QPEEASAEEERPEDQQEEEAAAAAAY 46
D D DPES P+ SP + +P + S P + A+ +A
Sbjct: 15 DDDSDPESETDPDAQAKAYVARVLSPPKSGLAFSRPSQLSTPAASPSASEPRAASRVSAV 74
Query: 47 LD----ELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102
+ LP LLL + + L A ++ VC ++LV W L+ + P
Sbjct: 75 SEPGLLSLPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWRLRALRRVRAPYPV 134
Query: 103 VEEERDHW 110
VEE+ W
Sbjct: 135 VEEKNFDW 142
>gi|110349786 Alstrom syndrome 1 [Homo sapiens]
Length = 4169
Score = 36.6 bits (83), Expect = 0.027
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 12 QPEEAS-PEEQPEEASAEEERPEDQQEEEAAAAAAYLDEL 50
+PE+ P E EE EEE E+++EE AAAAAA +D++
Sbjct: 2 EPEDLPWPGELEEEEEEEEEEEEEEEEEAAAAAAANVDDV 41
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 36.6 bits (83), Expect = 0.027
Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 19/114 (16%)
Query: 3 GDGDPESVGQPEEASPEEQPEEASA--------------EEERPEDQQEEEAAAAAAYLD 48
G G P S GQPE + P + P EA A +E PE ++ E+AAA ++
Sbjct: 386 GPGVPGSPGQPETSHPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAAEQWVS 445
Query: 49 ELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102
+ LL ++ EL C L CLR + P +L C LV E G
Sbjct: 446 --LQDLLSQLGRPFREYELWALC-LACLRALQTRPEHPAYL--CLDSVLVAEDG 494
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 36.2 bits (82), Expect = 0.035
Identities = 18/43 (41%), Positives = 22/43 (51%)
Query: 2 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAA 44
DGD D E + E PE EE EEE ED+ E+E A +
Sbjct: 165 DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 36.2 bits (82), Expect = 0.035
Identities = 18/43 (41%), Positives = 22/43 (51%)
Query: 2 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAA 44
DGD D E + E PE EE EEE ED+ E+E A +
Sbjct: 124 DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 166
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 36.2 bits (82), Expect = 0.035
Identities = 18/43 (41%), Positives = 22/43 (51%)
Query: 2 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAA 44
DGD D E + E PE EE EEE ED+ E+E A +
Sbjct: 117 DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 159
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.135 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,917,369
Number of Sequences: 37866
Number of extensions: 726169
Number of successful extensions: 7718
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 221
Number of HSP's successfully gapped in prelim test: 114
Number of HSP's that attempted gapping in prelim test: 5109
Number of HSP's gapped (non-prelim): 1719
length of query: 296
length of database: 18,247,518
effective HSP length: 102
effective length of query: 194
effective length of database: 14,385,186
effective search space: 2790726084
effective search space used: 2790726084
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.