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Search of human proteins with 157817023
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform
1 [Homo sapiens]
(1490 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 2994 0.0
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 2964 0.0
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 987 0.0
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 927 0.0
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens] 291 4e-78
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 250 6e-66
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 246 2e-64
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 246 2e-64
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 246 2e-64
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 246 2e-64
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 246 2e-64
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 246 2e-64
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 246 2e-64
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 246 2e-64
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 241 3e-63
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 237 5e-62
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 231 5e-60
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 230 7e-60
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 229 1e-59
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 224 5e-58
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 217 8e-56
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 215 2e-55
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 215 2e-55
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 213 1e-54
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 213 1e-54
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 211 4e-54
gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens] 206 1e-52
gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens] 206 2e-52
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 204 5e-52
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 203 9e-52
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 2994 bits (7761), Expect = 0.0
Identities = 1490/1490 (100%), Positives = 1490/1490 (100%)
Query: 1 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA 60
MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
Sbjct: 1 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA 60
Query: 61 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR 120
ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
Sbjct: 61 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR 120
Query: 121 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH 180
DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
Sbjct: 121 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH 180
Query: 181 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
Sbjct: 181 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
Query: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
Sbjct: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
Query: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
Sbjct: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 481 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP 540
VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
Sbjct: 481 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP 540
Query: 541 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN 600
TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
Sbjct: 541 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN 600
Query: 601 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ 660
SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
Sbjct: 601 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ 660
Query: 661 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG 720
RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
Sbjct: 661 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG 720
Query: 721 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ 780
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
Sbjct: 721 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ 780
Query: 781 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM 840
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
Sbjct: 781 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM 840
Query: 841 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW 900
KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
Sbjct: 841 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW 900
Query: 901 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW 960
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
Sbjct: 901 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW 960
Query: 961 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL 1020
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
Sbjct: 961 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL 1020
Query: 1021 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK 1080
KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
Sbjct: 1021 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK 1080
Query: 1081 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI 1140
NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
Sbjct: 1081 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI 1140
Query: 1141 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS 1200
HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
Sbjct: 1141 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS 1200
Query: 1201 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL 1260
STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
Sbjct: 1201 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL 1260
Query: 1261 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH 1320
PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
Sbjct: 1261 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH 1320
Query: 1321 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL 1380
QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
Sbjct: 1321 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL 1380
Query: 1381 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY 1440
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
Sbjct: 1381 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY 1440
Query: 1441 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY 1490
GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY
Sbjct: 1441 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY 1490
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 2964 bits (7684), Expect = 0.0
Identities = 1481/1490 (99%), Positives = 1481/1490 (99%), Gaps = 9/1490 (0%)
Query: 1 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA 60
MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
Sbjct: 1 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA 60
Query: 61 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR 120
ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
Sbjct: 61 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR 120
Query: 121 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH 180
DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
Sbjct: 121 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH 180
Query: 181 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
Sbjct: 181 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
Query: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
Sbjct: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
Query: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
Sbjct: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 481 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP 540
VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
Sbjct: 481 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP 540
Query: 541 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN 600
TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
Sbjct: 541 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN 600
Query: 601 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ 660
SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
Sbjct: 601 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ 660
Query: 661 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG 720
RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
Sbjct: 661 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG 720
Query: 721 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ 780
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
Sbjct: 721 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ 780
Query: 781 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM 840
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
Sbjct: 781 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM 840
Query: 841 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW 900
KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
Sbjct: 841 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW 900
Query: 901 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW 960
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
Sbjct: 901 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW 960
Query: 961 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL 1020
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
Sbjct: 961 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL 1020
Query: 1021 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK 1080
KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
Sbjct: 1021 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK 1080
Query: 1081 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI 1140
NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
Sbjct: 1081 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI 1140
Query: 1141 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS 1200
HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
Sbjct: 1141 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS 1200
Query: 1201 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL 1260
STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAA
Sbjct: 1201 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAA------- 1253
Query: 1261 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH 1320
EKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
Sbjct: 1254 --EKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH 1311
Query: 1321 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL 1380
QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
Sbjct: 1312 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL 1371
Query: 1381 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY 1440
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
Sbjct: 1372 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY 1431
Query: 1441 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY 1490
GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY
Sbjct: 1432 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY 1481
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 987 bits (2552), Expect = 0.0
Identities = 667/1528 (43%), Positives = 827/1528 (54%), Gaps = 247/1528 (16%)
Query: 61 ASLGTVIKPLVEYDDISSDSD---------------------------TFSDDMAFKLDR 93
AS G + PLVEY+D+SS S+ S + +
Sbjct: 134 ASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEG 193
Query: 94 RENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKR 153
E RR S K RH +HRR + K +S+ S + SGSS
Sbjct: 194 SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSS 253
Query: 154 SNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRET-PKSYKT 212
S A + SSS++ R SK H+ +T+ +E S +K+ K++R+ +T PK+Y+
Sbjct: 254 SGGRRKS-ASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYR- 311
Query: 213 VDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRR 272
+RRS SP +DDSP SH +S +KSP
Sbjct: 312 ----RRRSLSP------LGGRDDSPV--------------SHRASQSLRSRKSPSPAGG- 346
Query: 273 QSVSPPYKEPSAYQSSTRSPSPYSRR-QRSVSPYSRRRSSSYERSGSYSGR---SPSPYG 328
SPYSRR RS SPYSRRRS SY R SY SPSPY
Sbjct: 347 ------------------GSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYS 388
Query: 329 R---RRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSIS 385
RRS SP+ SP+ R+S KSRSRSP SRHS S S+ + S SRSRHSSIS
Sbjct: 389 SSSWRRSRSPY--------SPV-LRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSIS 439
Query: 386 PVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESK 445
P L L SSL AEL++ KK RA A AA+ E+
Sbjct: 440 PSTLTLKSSLAAELNKNKKARA--AEAAR--------------------------AAEAA 471
Query: 446 KLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKP 505
K + K ++A + ++ +T K +++T S+ + VKD+K
Sbjct: 472 KAAEATKAAEAA--AKAAKASNTSTPTKGNTETSA----SASQTNHVKDVKK-------- 517
Query: 506 IALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPP 565
I P P++ + PP+ +
Sbjct: 518 --------------------------IKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENN 551
Query: 566 LPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPV-QVSVKTQVSVTAAIPHLKT 624
L + V S S +K +VS + ++P + K + A + T
Sbjct: 552 LIVDKATKKAVIVGKESK---SAATKEESVSLKEKTKPLTPSIGAKEKEQHVALV----T 604
Query: 625 STLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELPGGDLSPPD 684
STLPPLPLPP+LP D + DS + + K VKKE E++ R LL DLPLPPELPGGD
Sbjct: 605 STLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD-DLSK 663
Query: 685 SPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKA 744
SPE K T Q K+RPKIC PRYGE ++ + DWGKRCVDKFDIIGIIGEGTYGQVYKA
Sbjct: 664 SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKA 722
Query: 745 KDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKK 804
+DKDTGE+VALKKVRLDNEKEGFPITAIREIKILRQL H+S++NMKEIVTDK+DALDFKK
Sbjct: 723 RDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKK 782
Query: 805 DKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSN 864
DKGAFYLVFEYMDHDLMGLLESGLVHF+E+HIKSFM+QLMEGL+YCHKKNFLHRDIKCSN
Sbjct: 783 DKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSN 842
Query: 865 ILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGC 924
ILLNN GQIKLADFGLARLY+SEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGC
Sbjct: 843 ILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGC 902
Query: 925 ILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLRE 984
ILGELFTKKPIFQAN ELAQLELISR+CGSPCPAVWPDVIKLPYFNTMKPKKQYRR+LRE
Sbjct: 903 ILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLRE 962
Query: 985 EFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWS 1044
EF FIP+AALDL D+ML LDPSKRCTAEQ LQ +FL+DVE SKM PPDLP WQDCHELWS
Sbjct: 963 EFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWS 1022
Query: 1045 KKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVKNSSPAPPQPAPGKVESGAGDAIGL 1104
KKRRRQ+Q G + ++ K RK+ + G + + ++P P+ G+ + +
Sbjct: 1023 KKRRRQKQMG-MTDDVSTIKAPRKDLSLG--LDDSRTNTPQGVLPSSQLKSQGSSNVAPV 1079
Query: 1105 -ADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEA 1163
Q LN SELA+LLNLLQS+T +++ Q+LNI N E QQQL +N L A
Sbjct: 1080 KTGPGQHLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGIL--A 1137
Query: 1164 TSQQQDSETMAPEESLKEAPSAPVILPSAE--QTTLEASSTPADMQNILAVLLSQLMKTQ 1221
T ++Q + +ES K I PS++ Q +E + A +Q+ AVLL+QL+K Q
Sbjct: 1138 TGEKQTDPSTPQQESSKPLGG---IQPSSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQ 1194
Query: 1222 EPAGS---LEENNSDKNSGPQGPRRTPTMPQEEAAACP-------------------PHI 1259
+ LEE + R P P + P I
Sbjct: 1195 QSKQKDVLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRI 1254
Query: 1260 LPPEKRPPEPPGPPPPPPPPPLVEGDL------------SSAPQELNPAVTAALLQLLS- 1306
LPP++RPPE PP PPP+ E DL SS+ + + V AALLQLL+
Sbjct: 1255 LPPDQRPPE------PPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQ 1308
Query: 1307 -QPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALT-- 1363
QP+ +P ++QA ++ + N +G++ + + D +S P L
Sbjct: 1309 HQPQDDPKREGGIDYQAGDTYVSTSDYKDN--FGSSSFSSAPYVSNDGLGSSSAPPLERR 1366
Query: 1364 ----ESLVQTLVKNRT-------------FSGSL--SHLGESSSYQGTGSVQFPGDQDLR 1404
S +Q+L T FS S S G Y G + F GD+D R
Sbjct: 1367 SFIGNSDIQSLDNYSTASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHR 1426
Query: 1405 F--ARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTGASSSGAGLHWGGP 1462
F + P+A+ P E S + A+ NYG S G W P
Sbjct: 1427 FEYSHGPIAVLANSSDPSTGPE--STHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSP 1484
Query: 1463 TQSSAYGKLYRGPTRVPPRGGRGRGVPY 1490
Q Y + YRG GRGRG+PY
Sbjct: 1485 AQGPGYSQGYRGHISTSTGRGRGRGLPY 1512
Score = 36.6 bits (83), Expect = 0.19
Identities = 89/417 (21%), Positives = 148/417 (35%), Gaps = 56/417 (13%)
Query: 5 ERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASLG 64
ER K GS +SG + S+ SS+S R SK R ++K SK+ P A
Sbjct: 241 ERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE----PPSAYK-- 294
Query: 65 TVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR-DLL 123
+P Y + ++ + RR R D HR Q RSR
Sbjct: 295 ---EPPKAYREDKTEPKAY---------RRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS 342
Query: 124 KAKQTEKEKSQEVSSKSGSMKDRISGSSKR--SNEETDDYGKAQVAKSSSKESR---SSK 178
A S+ + R S S R S E D + + SS + SR S
Sbjct: 343 PAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPV 402
Query: 179 LHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS 238
L + + R S RS+S + RSRS H S S+ S
Sbjct: 403 LRRSGKSRSRSPYSSRHSRSRSRHRLS-------------RSRSRHSSISPSTLTLKSSL 449
Query: 239 GASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRR 298
A ++ +R+ ++ K+ +T ++ + +A S+T +P+
Sbjct: 450 AAELNKN---KKARAAEAARAAEAAKAAEATKAAEAAA-----KAAKASNTSTPTK-GNT 500
Query: 299 QRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSR 358
+ S S ++ SPS G ++ ++ ++ PL K +
Sbjct: 501 ETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKND------KAKTKPPLQVTKVENNLIV 554
Query: 359 SPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKM 415
A + + K ++++ S+ PL S+GA K+KE+ A + +
Sbjct: 555 DKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGA----KEKEQHVALVTSTL 607
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 927 bits (2397), Expect = 0.0
Identities = 646/1525 (42%), Positives = 796/1525 (52%), Gaps = 301/1525 (19%)
Query: 61 ASLGTVIKPLVEYDDISSDSD---------------------------TFSDDMAFKLDR 93
AS G + PLVEY+D+SS S+ S + +
Sbjct: 134 ASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEG 193
Query: 94 RENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKR 153
E RR S K RH +HRR + K +S+ S + SGSS
Sbjct: 194 SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSS 253
Query: 154 SNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRET-PKSYKT 212
S A + SSS++ R SK H+ +T+ +E S +K+ K++R+ +T PK+Y+
Sbjct: 254 SGGRRKS-ASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYR- 311
Query: 213 VDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRR 272
+RRS SP +DDSP SH +S +KSP
Sbjct: 312 ----RRRSLSP------LGGRDDSPV--------------SHRASQSLRSRKSPSPAGG- 346
Query: 273 QSVSPPYKEPSAYQSSTRSPSPYSRR-QRSVSPYSRRRSSSYERSGSYSGR---SPSPYG 328
SPYSRR RS SPYSRRRS SY R SY SPSPY
Sbjct: 347 ------------------GSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYS 388
Query: 329 R---RRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSIS 385
RRS SP+ SP+ R+S KSRSRSP SRHS S S+ + S SRSRHSSIS
Sbjct: 389 SSSWRRSRSPY--------SPV-LRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSIS 439
Query: 386 PVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESK 445
P L L SSL AEL++ KK RA A AA+ E+
Sbjct: 440 PSTLTLKSSLAAELNKNKKARA--AEAAR--------------------------AAEAA 471
Query: 446 KLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKP 505
K + K ++A + ++ +T K +++T S+ + VKD+K
Sbjct: 472 KAAEATKAAEAA--AKAAKASNTSTPTKGNTETSA----SASQTNHVKDVKK-------- 517
Query: 506 IALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPP 565
I P P++ + PP+ +
Sbjct: 518 --------------------------IKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENN 551
Query: 566 LPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPV-QVSVKTQVSVTAAIPHLKT 624
L + V S S +K +VS + ++P + K + A + T
Sbjct: 552 LIVDKATKKAVIVGKESK---SAATKEESVSLKEKTKPLTPSIGAKEKEQHVALV----T 604
Query: 625 STLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELPGGDLSPPD 684
STLPPLPLPP+LP D + DS + + K VKKE E++ R LL DLPLPPELPGGD
Sbjct: 605 STLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD-DLSK 663
Query: 685 SPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKA 744
SPE K T Q K+RPKIC PRYGE ++ + DWGKRCVDKFDIIGIIGEGTYGQVYKA
Sbjct: 664 SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKA 722
Query: 745 KDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKK 804
+DKDTGE+VALKKVRLDNEKEGFPITAIREIKILRQL H+S++NMKEIVTDK+DALDFKK
Sbjct: 723 RDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKK 782
Query: 805 DKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSN 864
DKGAFYLVFEYMDHDLMGLLESGLVHF+E+HIKSFM+QLMEGL+YCHKKNFLHRDIKCSN
Sbjct: 783 DKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSN 842
Query: 865 ILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGC 924
ILLNN GQIKLADFGLARLY+SEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGC
Sbjct: 843 ILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGC 902
Query: 925 ILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLRE 984
ILGELFTKKPIFQAN ELAQLELISR+CGSPCPAVWPDVIKLPYFNTMKPKKQYRR+LRE
Sbjct: 903 ILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLRE 962
Query: 985 EFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWS 1044
EF FIP+AALDL D+ML LDPSKRCTAEQ LQ +FL+DVE SKM PPDLP WQDCHELWS
Sbjct: 963 EFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWS 1022
Query: 1045 KKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVKNSSPAPPQPAPGKVESGAGDAIGL 1104
KKRRRQ+Q G + ++ K RK+ + G + +S PQ G+
Sbjct: 1023 KKRRRQKQMG-MTDDVSTIKAPRKDLSLG-----LDDSRTNTPQ--------------GV 1062
Query: 1105 ADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEAT 1164
+Q +Q V + QTD S PQ E + L +
Sbjct: 1063 LPSSQLKSQGSSNVAPG--EKQTDPSTPQQ----------ESSKPLGGI----------- 1099
Query: 1165 SQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPA 1224
Q S+T+ P+ +E + A +Q+ AVLL+QL+K Q+
Sbjct: 1100 --QPSSQTIQPK--------------------VETDAAQAAVQSAFAVLLTQLIKAQQSK 1137
Query: 1225 GS---LEENNSDKNSGPQGPRRTPTMPQEEAAACP-------------------PHILPP 1262
LEE + R P P + P ILPP
Sbjct: 1138 QKDVLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRILPP 1197
Query: 1263 EKRPPEPPGPPPPPPPPPLVEGDL------------SSAPQELNPAVTAALLQLLS--QP 1308
++RPPE PP PPP+ E DL SS+ + + V AALLQLL+ QP
Sbjct: 1198 DQRPPE------PPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQP 1251
Query: 1309 EAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALT----- 1363
+ +P ++QA ++ + N +G++ + + D +S P L
Sbjct: 1252 QDDPKREGGIDYQAGDTYVSTSDYKDN--FGSSSFSSAPYVSNDGLGSSSAPPLERRSFI 1309
Query: 1364 -ESLVQTLVKNRT-------------FSGSL--SHLGESSSYQGTGSVQFPGDQDLRF-- 1405
S +Q+L T FS S S G Y G + F GD+D RF
Sbjct: 1310 GNSDIQSLDNYSTASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEY 1369
Query: 1406 ARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTGASSSGAGLHWGGPTQS 1465
+ P+A+ P E S + A+ NYG S G W P Q
Sbjct: 1370 SHGPIAVLANSSDPSTGPE--STHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSPAQG 1427
Query: 1466 SAYGKLYRGPTRVPPRGGRGRGVPY 1490
Y + YRG GRGRG+PY
Sbjct: 1428 PGYSQGYRGHISTSTGRGRGRGLPY 1452
Score = 36.6 bits (83), Expect = 0.19
Identities = 89/417 (21%), Positives = 148/417 (35%), Gaps = 56/417 (13%)
Query: 5 ERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASLG 64
ER K GS +SG + S+ SS+S R SK R ++K SK+ P A
Sbjct: 241 ERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE----PPSAYK-- 294
Query: 65 TVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR-DLL 123
+P Y + ++ + RR R D HR Q RSR
Sbjct: 295 ---EPPKAYREDKTEPKAY---------RRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS 342
Query: 124 KAKQTEKEKSQEVSSKSGSMKDRISGSSKR--SNEETDDYGKAQVAKSSSKESR---SSK 178
A S+ + R S S R S E D + + SS + SR S
Sbjct: 343 PAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPV 402
Query: 179 LHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS 238
L + + R S RS+S + RSRS H S S+ S
Sbjct: 403 LRRSGKSRSRSPYSSRHSRSRSRHRLS-------------RSRSRHSSISPSTLTLKSSL 449
Query: 239 GASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRR 298
A ++ +R+ ++ K+ +T ++ + +A S+T +P+
Sbjct: 450 AAELNKN---KKARAAEAARAAEAAKAAEATKAAEAAA-----KAAKASNTSTPTK-GNT 500
Query: 299 QRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSR 358
+ S S ++ SPS G ++ ++ ++ PL K +
Sbjct: 501 ETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKND------KAKTKPPLQVTKVENNLIV 554
Query: 359 SPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKM 415
A + + K ++++ S+ PL S+GA K+KE+ A + +
Sbjct: 555 DKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGA----KEKEQHVALVTSTL 607
>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
Length = 372
Score = 291 bits (744), Expect = 4e-78
Identities = 160/366 (43%), Positives = 228/366 (62%), Gaps = 20/366 (5%)
Query: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
V K++ + IG+GT+G+V+KA+ + TG+ VALKKV ++NEKEGFPITA+REIKIL+ L H
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL 843
+VVN+ EI K A + + KG+ YLVF++ +HDL GLL + LV F+ IK M+ L
Sbjct: 76 ENVVNLIEICRTK--ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 844 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYN-SEESRP--YTNKVITLW 900
+ GL Y H+ LHRD+K +N+L+ G +KLADFGLAR ++ ++ S+P YTN+V+TLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 901 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW 960
YRPPELLLGE Y P ID+W GCI+ E++T+ PI Q N E QL LIS+LCGS P VW
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVW 253
Query: 961 PDVIKLPYFNTMKPKKQYRRRLREEFSFI--PSAALDLLDHMLTLDPSKRCTAEQTLQSD 1018
P+V + ++ K +R++++ ALDL+D +L LDP++R ++ L D
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 1019 FLKDVELSKMAPPDL-----PHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSG 1073
F S P DL H E + RR+ G + + +++ TT+
Sbjct: 314 FF----WSDPMPSDLKGMLSTHLTSMFEYLAPPRRK----GSQITQQSTNQSRNPATTNQ 365
Query: 1074 TSTEPV 1079
T E V
Sbjct: 366 TEFERV 371
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 250 bits (639), Expect = 6e-66
Identities = 132/316 (41%), Positives = 187/316 (59%), Gaps = 11/316 (3%)
Query: 722 RCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL 781
R V +F+ + IGEGTYG VY+A+D T E+VALKKVR+D EK+G PI+++REI +L +L
Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93
Query: 782 IHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMK 841
H ++V +KE+V + +LV Y + DL LLE+ FSE +K +
Sbjct: 94 RHPNIVELKEVVVGNH--------LESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVL 145
Query: 842 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWY 901
Q++ GL+Y H+ +HRD+K SN+L+ + G +K ADFGLAR Y +P T KV+TLWY
Sbjct: 146 QVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPV-KPMTPKVVTLWY 204
Query: 902 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWP 961
R PELLLG T +ID+W+ GCIL EL +P+ E+ Q++LI +L G+P +WP
Sbjct: 205 RAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWP 264
Query: 962 DVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLK 1021
KLP +KQ L+ +F ++ A L LL + DP KR TA L+S + K
Sbjct: 265 GFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFK 324
Query: 1022 DVEL--SKMAPPDLPH 1035
+ L P PH
Sbjct: 325 EKPLPCEPELMPTFPH 340
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 358 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALLPIELKQELPKYLPAL------------ 404
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 405 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 462
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 463 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 514
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 515 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 573
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N E+ Q+ + + G+P
Sbjct: 574 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPS 633
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 634 EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 693
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 694 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 726
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 727 -------SPRPPEGGLGYSQLGDDD 744
Score = 40.0 bits (92), Expect = 0.017
Identities = 59/301 (19%), Positives = 106/301 (35%), Gaps = 27/301 (8%)
Query: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFK--- 90
E RL + R + S + G + + T+ +D D D +A K
Sbjct: 31 EIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
Query: 91 -LDRRENDERRGSDRSDRLHKH---------RHHQHRRSRDLLKAKQTEKEKSQEVSSK- 139
+ R+E R ++ KH R +HR +D + ++ E++K +E++ +
Sbjct: 90 QMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR-REWERQKRREMAREH 148
Query: 140 SGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSK 199
S +DR+ ++ E K + + +E + + E+ RKERE + R
Sbjct: 149 SRRERDRLEQLERKRERER----KMREQQKEQREQKERERRAEERRKEREAR-----REV 199
Query: 200 SHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDD--SPSGASYGQDYDLSPSRSHTSS 257
S R + Y SRSP R + + D P ++ DL S
Sbjct: 200 SAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD 259
Query: 258 NYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSG 317
+ + S++ S S +E + S S S + + S
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319
Query: 318 S 318
S
Sbjct: 320 S 320
Score = 38.9 bits (89), Expect = 0.037
Identities = 52/231 (22%), Positives = 90/231 (38%), Gaps = 31/231 (13%)
Query: 92 DRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
DR E D+ ++ + HR+ K+ EK K V K+R
Sbjct: 75 DRGEEDDSLAIKPPQQMSRKEKVHHRKDE-----KRKEKWKHARV-------KEREHERR 122
Query: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE-LKSGHKDRSKSHRKRETPKSY 210
KR EE D A+ + + ++ +E +R+ER+ L+ + R + + RE K
Sbjct: 123 KRHREEQDK------ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ 176
Query: 211 KTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTS 270
+ + +R R+ R+ ++++ S + +DY SH S S + P
Sbjct: 177 R--EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR---SPPRPPRERF 231
Query: 271 RRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSG 321
P KE + S + +S S R++SS E S + SG
Sbjct: 232 ELGDGRKPVKEEKMEERDLLSD------LQDISD-SERKTSSAESSSAESG 275
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 368 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALLPIELKQELPKYLPAL------------ 414
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 415 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 473 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 524
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 525 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 583
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N E+ Q+ + + G+P
Sbjct: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPS 643
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 644 EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 703
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 704 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 736
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 737 -------SPRPPEGGLGYSQLGDDD 754
Score = 39.7 bits (91), Expect = 0.022
Identities = 58/290 (20%), Positives = 106/290 (36%), Gaps = 37/290 (12%)
Query: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR 93
E RL + R + S + G + + T+ +D D D +A K +
Sbjct: 31 EIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
Query: 94 RENDERRGSDRSD--RLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
+ + + + R D R K RHH H E K V + + R
Sbjct: 90 QMSRKEKVHHRKDEKRKEKCRHHSH----------SAEGGKHARVKEREHERRKRHREEQ 139
Query: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYK 211
++ E + + ++A+ S+ R +L + + ++ERE K + + + +K
Sbjct: 140 DKARREWERQKRREMAREHSRRER-DRLEQLERKRERERKMREQQKEQREQK-------- 190
Query: 212 TVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSR 271
+R R+ R+ ++++ S + +DY SH S S + P
Sbjct: 191 -----ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR---SPPRPPRERFE 242
Query: 272 RQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSG 321
P KE + S + +S S R++SS E S + SG
Sbjct: 243 LGDGRKPVKEEKMEERDLLSD------LQDISD-SERKTSSAESSSAESG 285
Score = 33.5 bits (75), Expect = 1.6
Identities = 18/70 (25%), Positives = 32/70 (45%)
Query: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179
RDLL Q + ++ SS S + SGS + EE ++ + ++ S +E +
Sbjct: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 317
Query: 180 HKEKTRKERE 189
+E+T E
Sbjct: 318 EEEETGSNSE 327
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9
[Homo sapiens]
Length = 771
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 359 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 405
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 406 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 463
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 464 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 515
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 516 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 574
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 575 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 634
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 635 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 694
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 695 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 727
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 728 -------SPRPPEGGLGYSQLGDDD 745
Score = 35.8 bits (81), Expect = 0.32
Identities = 49/283 (17%), Positives = 107/283 (37%), Gaps = 14/283 (4%)
Query: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR 93
E RL + R + S + G + + T+ +D D D +A K +
Sbjct: 31 EIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
Query: 94 RENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKR 153
+ + + + R D K + H + ++ ++ + Q+ + + + R + +
Sbjct: 90 QMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREH 149
Query: 154 SNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTV 213
S E D ++ + K R K+ +E+ +++RE K ++R R++E ++ + V
Sbjct: 150 SRRERD-----RLEQLERKRERERKM-REQQKEQREQKE--RERRAEERRKER-EARREV 200
Query: 214 DSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQ 273
+ R R + +S SP + ++L R + + S Q
Sbjct: 201 SAHHRTMREDYSDKVKASHWSRSPPRPP-RERFELGDGRKPVK---EEKMEERDLLSDLQ 256
Query: 274 SVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERS 316
+S ++ S+ +SS+ S + S+ E S
Sbjct: 257 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 299
Score = 33.5 bits (75), Expect = 1.6
Identities = 18/70 (25%), Positives = 32/70 (45%)
Query: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179
RDLL Q + ++ SS S + SGS + EE ++ + ++ S +E +
Sbjct: 249 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 308
Query: 180 HKEKTRKERE 189
+E+T E
Sbjct: 309 EEEETGSNSE 318
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8
[Homo sapiens]
Length = 780
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 368 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 414
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 415 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 473 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 524
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 525 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 583
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 584 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 643
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 644 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 703
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 704 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 736
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 737 -------SPRPPEGGLGYSQLGDDD 754
Score = 43.9 bits (102), Expect = 0.001
Identities = 92/443 (20%), Positives = 151/443 (34%), Gaps = 76/443 (17%)
Query: 110 KHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDR-----ISGSSKRSNEETDDYGKA 164
K R + ++ + K ++ S+ S + G ++D I S R + +D G+
Sbjct: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
Query: 165 Q---VAKSSSKESRSSKLHKEK------------TRKERELKSGHKDRSKSHRKRETPKS 209
K + SR K+H K KERE +R K HR+ E K+
Sbjct: 80 DDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKERE-----HERRKRHRE-EQDKA 133
Query: 210 YKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQD--YDLSPSRSHTSSNYDSYKKSPG 267
+ + KRR + + S+++ G +D L R + K+
Sbjct: 134 RREWERQKRREMA-----REHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQRE 188
Query: 268 STSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPY 327
R + KE A RR+ S + R S + S+ RSP
Sbjct: 189 QKERERRAEERRKEREA------------RREVSAHHRTMREDYSDKVKASHWSRSPPRP 236
Query: 328 GRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPV 387
R R + R P+ K K R S S++K SS+ S +
Sbjct: 237 PRER------FELGDGRKPV---KEEKMEERDLLSDLQDISDSERKTSSAESSSA----- 282
Query: 388 RLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKL 447
S G+E +++E + + +E + +E +S S++
Sbjct: 283 ----ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-----EEEEEEETGSNSEEASEQS 333
Query: 448 PRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIA 507
V E+ + D E N HL ++ D + +E E+ +GT S A
Sbjct: 334 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE------VGEGTPQSS--A 385
Query: 508 LKEEIVTPKETETSEKETPPPLP 530
L E P S E LP
Sbjct: 386 LTEGDYVPDSPALSPIELKQELP 408
Score = 36.2 bits (82), Expect = 0.24
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 9/195 (4%)
Query: 84 SDDMAFKLDRRENDER-RGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGS 142
+D + DR E ER R +R R + + + + ++ E+E +EVS+ +
Sbjct: 156 NDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRT 215
Query: 143 MKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHR 202
M++ S K S+ + + + K KE+ +ER+L S +D S S R
Sbjct: 216 MREDYSDKVKASHWSR---SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 272
Query: 203 KRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDD-SPSGASYGQDYDLSPSRSHTSSNYDS 261
K + +S S + S S + + ++++ S S S ++ + T SN +
Sbjct: 273 KTSSAES----SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
Query: 262 YKKSPGSTSRRQSVS 276
+ + +S
Sbjct: 329 ASEQSAEEVSEEEMS 343
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5
[Homo sapiens]
Length = 748
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 336 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 382
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 383 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 440
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 441 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 492
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 493 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 551
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 552 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 611
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 612 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 671
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 672 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 704
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 705 -------SPRPPEGGLGYSQLGDDD 722
Score = 39.3 bits (90), Expect = 0.029
Identities = 61/281 (21%), Positives = 104/281 (37%), Gaps = 61/281 (21%)
Query: 74 DDISSDSDTFSDDMAFK----LDRREN-----DERRGSDRSDRLH------------KHR 112
+D D D +A K + R+E DE+R R R H K R
Sbjct: 36 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKER 95
Query: 113 HHQ----HRRSRDLLKAKQTEKEKSQEVSSK-SGSMKDRISGSSKRSNEETDDYGKAQVA 167
H+ HR +D + ++ E++K +E++ + S +DR+ ++ E K +
Sbjct: 96 EHERRKRHREEQDKAR-REWERQKRREMAREHSRRERDRLEQLERKRERER----KMREQ 150
Query: 168 KSSSKESRSSKLHKEKTRKERE-----------LKSGHKDRSK-SHRKRETPK------- 208
+ +E + + E+ RKERE ++ + D+ K SH R P+
Sbjct: 151 QKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFE 210
Query: 209 ---SYKTVDSPKRRSR---SPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSY 262
K V K R S + SDS ++ S +S S S S +
Sbjct: 211 LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE-----SGSGSEEEEEEEEE 265
Query: 263 KKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVS 303
++ GSTS +E ++ + S + VS
Sbjct: 266 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 306
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4
[Homo sapiens]
Length = 737
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 325 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 371
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 372 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 429
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 430 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 481
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 482 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 540
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 541 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 600
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 601 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 660
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 661 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 693
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 694 -------SPRPPEGGLGYSQLGDDD 711
Score = 39.7 bits (91), Expect = 0.022
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 18/200 (9%)
Query: 86 DMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKD 145
+MA + RRE D +R + Q + R+ Q E+E+ E K +
Sbjct: 110 EMAREHSRRERDRLEQLERKRERERKMREQQKEQRE-----QKERERRAEERRKEREARR 164
Query: 146 RISGSSKRSNEETDDYGKA-QVAKSSSKESR-------SSKLHKEKTRKERELKSGHKDR 197
+S + E+ D KA ++S + R K KE+ +ER+L S +D
Sbjct: 165 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 224
Query: 198 SKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDD-SPSGASYGQDYDLSPSRSHTS 256
S S RK + +S S + S S + + ++++ S S S ++ + T
Sbjct: 225 SDSERKTSSAES----SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 280
Query: 257 SNYDSYKKSPGSTSRRQSVS 276
SN + + + +S
Sbjct: 281 SNSEEASEQSAEEVSEEEMS 300
Score = 39.3 bits (90), Expect = 0.029
Identities = 51/230 (22%), Positives = 89/230 (38%), Gaps = 23/230 (10%)
Query: 93 RRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSK 152
R ++ E RG + K R+ K + EK +E K+R K
Sbjct: 35 REDSMEDRGEEDDSLAIKPPQQMSRKE----KVHHRKDEKRKEKKHARVKEKEREHERRK 90
Query: 153 RSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE-LKSGHKDRSKSHRKRETPKSYK 211
R EE D A+ + + ++ +E +R+ER+ L+ + R + + RE K +
Sbjct: 91 RHREEQDK------ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 144
Query: 212 TVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSR 271
+ +R R+ R+ ++++ S + +DY SH S S + P
Sbjct: 145 --EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR---SPPRPPRERFE 199
Query: 272 RQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSG 321
P KE + S + +S S R++SS E S + SG
Sbjct: 200 LGDGRKPVKEEKMEERDLLSD------LQDISD-SERKTSSAESSSAESG 242
Score = 38.1 bits (87), Expect = 0.064
Identities = 83/394 (21%), Positives = 130/394 (32%), Gaps = 65/394 (16%)
Query: 139 KSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRS 198
+ SM+DR + + + + E R K H KERE +R
Sbjct: 35 REDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKERE-----HERR 89
Query: 199 KSHRKRETPKSYKTVDSPKRR--SRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTS 256
K HR+ E K+ + + KRR +R R+ D +Q L R
Sbjct: 90 KRHRE-EQDKARREWERQKRREMAREHSRRERDRLEQ--------------LERKRERER 134
Query: 257 SNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERS 316
+ K+ R + KE A RR+ S + R S +
Sbjct: 135 KMREQQKEQREQKERERRAEERRKEREA------------RREVSAHHRTMREDYSDKVK 182
Query: 317 GSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSS 376
S+ RSP R R + R P+ K K R S S++K SS
Sbjct: 183 ASHWSRSPPRPPRER------FELGDGRKPV---KEEKMEERDLLSDLQDISDSERKTSS 233
Query: 377 SRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVE 436
+ S + S G+E +++E + + +E + +E
Sbjct: 234 AESSSA---------ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-----EEEEEEET 279
Query: 437 AKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLK 496
+S S++ V E+ + D E N HL ++ D + +E E+
Sbjct: 280 GSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE------V 333
Query: 497 AQGTRDSKPIALKEEIVTPKETETSEKETPPPLP 530
+GT S AL E P S E LP
Sbjct: 334 GEGTPQSS--ALTEGDYVPDSPALSPIELKQELP 365
Score = 37.7 bits (86), Expect = 0.083
Identities = 48/223 (21%), Positives = 83/223 (37%), Gaps = 26/223 (11%)
Query: 90 KLDRRENDE-RRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRIS 148
K R E D+ RR +R R R H RR RD L+ + ++E+ +++ +
Sbjct: 90 KRHREEQDKARREWERQKRREMAREHS-RRERDRLEQLERKRERERKMREQ--------- 139
Query: 149 GSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKE--RELKSGHKDRSKSHRKRET 206
K E+ + +A+ + + R H R++ ++K+ H RS RE
Sbjct: 140 --QKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 197
Query: 207 ------PKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYD 260
K K +R S + SDS ++ S +S S S S +
Sbjct: 198 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE-----SGSGSEEEEEEE 252
Query: 261 SYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVS 303
++ GSTS +E ++ + S + VS
Sbjct: 253 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 295
Score = 34.7 bits (78), Expect = 0.71
Identities = 38/231 (16%), Positives = 89/231 (38%), Gaps = 12/231 (5%)
Query: 92 DRRENDER------RGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKD 145
DR E D+ + R +++H HR + R+ + + K+ E+E + + K
Sbjct: 41 DRGEEDDSLAIKPPQQMSRKEKVH-HRKDEKRKEKKHARVKEKEREHERRKRHREEQDKA 99
Query: 146 RISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRE 205
R ++ E ++ + + + E + + K + +++ + + ++R R++E
Sbjct: 100 RREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE 159
Query: 206 TPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKS 265
++ + V + R R + +S SP + ++L R + +
Sbjct: 160 R-EARREVSAHHRTMREDYSDKVKASHWSRSPPRPP-RERFELGDGRKPVK---EEKMEE 214
Query: 266 PGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERS 316
S Q +S ++ S+ +SS+ S + S+ E S
Sbjct: 215 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 265
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3
[Homo sapiens]
Length = 526
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 114 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 160
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 161 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 218
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 219 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 270
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 271 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 329
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 330 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 389
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 390 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 449
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 450 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 482
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 483 -------SPRPPEGGLGYSQLGDDD 500
Score = 33.5 bits (75), Expect = 1.6
Identities = 18/70 (25%), Positives = 32/70 (45%)
Query: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179
RDLL Q + ++ SS S + SGS + EE ++ + ++ S +E +
Sbjct: 4 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 63
Query: 180 HKEKTRKERE 189
+E+T E
Sbjct: 64 EEEETGSNSE 73
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2
[Homo sapiens]
Length = 782
Score = 246 bits (627), Expect = 2e-64
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 370 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 416
Query: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 417 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 474
Query: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 475 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 526
Query: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 527 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 585
Query: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 586 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 645
Query: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 646 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 705
Query: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 706 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 738
Query: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
SP PP+ G + G D
Sbjct: 739 -------SPRPPEGGLGYSQLGDDD 756
Score = 40.0 bits (92), Expect = 0.017
Identities = 68/321 (21%), Positives = 117/321 (36%), Gaps = 62/321 (19%)
Query: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFK--- 90
E RL + R + S + G + + T+ +D D D +A K
Sbjct: 31 EIKRLKNSDDRDSKRDSLEEGELRDHRMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
Query: 91 -LDRREN-----DERRGSDRSDRLH------------KHRHHQ----HRRSRDLLKAKQT 128
+ R+E DE+R R R H K R H+ HR +D + ++
Sbjct: 90 QMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKAR-REW 148
Query: 129 EKEKSQEVSSK-SGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKE 187
E++K +E++ + S +DR+ ++ E K + + +E + + E+ RKE
Sbjct: 149 ERQKRREMAREHSRRERDRLEQLERKRERER----KMREQQKEQREQKERERRAEERRKE 204
Query: 188 RE-----------LKSGHKDRSK-SHRKRETPK----------SYKTVDSPKRRSR---S 222
RE ++ + D+ K SH R P+ K V K R S
Sbjct: 205 REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLS 264
Query: 223 PHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEP 282
+ SDS ++ S +S S S S + ++ GSTS +E
Sbjct: 265 DLQDISDSERKTSSAESSSAE-----SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 319
Query: 283 SAYQSSTRSPSPYSRRQRSVS 303
++ + S + VS
Sbjct: 320 EEEETGSNSEEASEQSAEEVS 340
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 241 bits (616), Expect = 3e-63
Identities = 133/307 (43%), Positives = 188/307 (61%), Gaps = 13/307 (4%)
Query: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
+D F + IGEGTYG VYKAK+++TG+LVALKK+RLD E EG P TAIREI +L++L H
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDH-IKSFMKQ 842
++V + ++V +++ YLVFE++ DL ++S H IKS++ Q
Sbjct: 61 PNIVRLLDVVHNERK----------LYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQ 110
Query: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
L++G+ +CH +HRD+K N+L+N G IKLADFGLAR + R YT++V+TLWYR
Sbjct: 111 LLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVP-LRTYTHEVVTLWYR 169
Query: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
PE+LLG + YT A+D+WS GCI E+ T+K +F + E+ QL I R+ G+P WP
Sbjct: 170 APEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPG 229
Query: 963 VIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
V +LP + P K R+ L E + DLL +L DPS+R TA+ L +
Sbjct: 230 VTQLPDYKGSFP-KWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
Query: 1023 VELSKMA 1029
E S A
Sbjct: 289 PEPSPAA 295
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 237 bits (605), Expect = 5e-62
Identities = 131/305 (42%), Positives = 187/305 (61%), Gaps = 21/305 (6%)
Query: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
++ F + IGEGTYG VYKA++K TGE+VALKK+RLD E EG P TAIREI +L++L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLE-SGLVHFSEDHIKSFMKQ 842
++V + +++ + YLVFE++ DL ++ S L IKS++ Q
Sbjct: 61 PNIVKLLDVI----------HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQ 110
Query: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
L++GL +CH LHRD+K N+L+N G IKLADFGLAR + R YT++V+TLWYR
Sbjct: 111 LLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV-RTYTHEVVTLWYR 169
Query: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
PE+LLG + Y+ A+D+WS GCI E+ T++ +F + E+ QL I R G+P VWP
Sbjct: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPG 229
Query: 963 VIKLPYFNTMKPKKQYRRRLREEFS-FIPSAALD---LLDHMLTLDPSKRCTAEQTLQSD 1018
V +P + K + + R++FS +P D LL ML DP+KR +A+ L
Sbjct: 230 VTSMPDY-----KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
Query: 1019 FLKDV 1023
F +DV
Sbjct: 285 FFQDV 289
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 231 bits (588), Expect = 5e-60
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 12/312 (3%)
Query: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLI- 782
+D++ I+G IGEG +G V+KAK +TGE+VALKKV L ++GFP A+REIK L+++
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
Query: 783 HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842
++ VV +K + G F L FE+M DL ++ ++ +KS+++
Sbjct: 61 NQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 110
Query: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
L++G+ +CH N +HRD+K +N+L++ SGQ+K+ADFGLAR+++ + SR YT++V T WYR
Sbjct: 111 LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYR 170
Query: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
PELL G +Y +D+WS GCI+GEL P+F ++ QL + R+ G+P P VWP+
Sbjct: 171 APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPE 230
Query: 963 VIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
+ +LP +N + K+Q L E + ALDLL L P +R A + L +
Sbjct: 231 LTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFT 290
Query: 1023 VELSKMAPPDLP 1034
L P +LP
Sbjct: 291 APL-PAHPSELP 301
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 230 bits (587), Expect = 7e-60
Identities = 122/294 (41%), Positives = 183/294 (62%), Gaps = 14/294 (4%)
Query: 733 IGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEI 792
IGEGTYG VYK + K TG++VA+KK+RL++E+EG P TAIREI +L++L H ++V+++++
Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69
Query: 793 VTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLES--GLVHFSEDHIKSFMKQLMEGLEYC 850
+ QD+ YL+FE++ DL L+S + +KS++ Q+++G+ +C
Sbjct: 70 LM--QDS--------RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 851 HKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGE 910
H + LHRD+K N+L+++ G IKLADFGLAR + R YT++V+TLWYR PE+LLG
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEVVTLWYRSPEVLLGS 178
Query: 911 ERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFN 970
RY+ +D+WS G I EL TKKP+F + E+ QL I R G+P VWP+V L +
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
Query: 971 TMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVE 1024
PK + L + LDLL ML DP+KR + + L + D++
Sbjct: 239 NTFPKWK-PGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 229 bits (584), Expect = 1e-59
Identities = 122/294 (41%), Positives = 182/294 (61%), Gaps = 14/294 (4%)
Query: 733 IGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEI 792
IGEGTYG VYK + K TG++VA+KK+RL++E+EG P TAIREI +L++L H ++V+++++
Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69
Query: 793 VTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLES--GLVHFSEDHIKSFMKQLMEGLEYC 850
+ QD+ YL+FE++ DL L+S + +KS++ Q+++G+ +C
Sbjct: 70 LM--QDS--------RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 851 HKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGE 910
H + LHRD+K N+L+++ G IKLADFGLAR + R YT++ ITLWYR PE+LLG
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEAITLWYRSPEVLLGS 178
Query: 911 ERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFN 970
RY+ +D+WS G I EL TKKP+F + E+ QL I R G+P VWP+V L +
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
Query: 971 TMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVE 1024
PK + L + LDLL ML DP+KR + + L + D++
Sbjct: 239 NTFPKWK-PGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 224 bits (571), Expect = 5e-58
Identities = 123/303 (40%), Positives = 189/303 (62%), Gaps = 19/303 (6%)
Query: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
+ K++ + IGEGTYG V+KAK+++T E+VALK+VRLD++ EG P +A+REI +L++L H
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 784 RSVVNMKEIV-TDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842
+++V + +++ +DK+ LVFE+ D DL +S + +KSF+ Q
Sbjct: 61 KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
Query: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
L++GL +CH +N LHRD+K N+L+N +G++KLADFGLAR + R Y+ +V+TLWYR
Sbjct: 110 LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGI-PVRCYSAEVVTLWYR 168
Query: 903 PPELLLGEERYTPAIDVWSCGCILGELFTK-KPIFQANLELAQLELISRLCGSPCPAVWP 961
PP++L G + Y+ +ID+WS GCI EL +P+F N QL+ I RL G+P WP
Sbjct: 169 PPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWP 228
Query: 962 DVIKLPYFNTMKPKKQY--RRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDF 1019
+ KLP + KP Y L + + DLL ++L +P +R +AE+ LQ +
Sbjct: 229 SMTKLPDY---KPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
Query: 1020 LKD 1022
D
Sbjct: 286 FSD 288
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 217 bits (552), Expect = 8e-56
Identities = 130/385 (33%), Positives = 202/385 (52%), Gaps = 27/385 (7%)
Query: 640 DDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYK 699
D++ SP + + + LP +P G L P P QP
Sbjct: 118 DEVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSP----PFDQPMS 173
Query: 700 KRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVR 759
+R RR + S+ G ++ + + +GEGTY VYK + K T LVALK++R
Sbjct: 174 RR---------SRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIR 224
Query: 760 LDNEKEGFPITAIREIKILRQLIHRSVVNMKEIV-TDKQDALDFKKDKGAFYLVFEYMDH 818
L++E EG P TAIRE+ +L+ L H ++V + +IV TDK + LVFEY+D
Sbjct: 225 LEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDK-----------SLTLVFEYLDK 272
Query: 819 DLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADF 878
DL ++ S ++K F+ Q++ GL YCH++ LHRD+K N+L+N G++KLADF
Sbjct: 273 DLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADF 332
Query: 879 GLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQA 938
GLAR S ++ Y+N+V+TLWYRPP++LLG Y+ ID+W GCI E+ + +P+F
Sbjct: 333 GLARA-KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPG 391
Query: 939 NLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLD 998
+ +L LI RL G+P WP + F K + L + S ++L+
Sbjct: 392 STVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELIT 451
Query: 999 HMLTLDPSKRCTAEQTLQSDFLKDV 1023
L + KR +AE+ ++ + + +
Sbjct: 452 KFLQYESKKRVSAEEAMKHVYFRSL 476
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 215 bits (548), Expect = 2e-55
Identities = 118/308 (38%), Positives = 177/308 (57%), Gaps = 12/308 (3%)
Query: 712 RRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITA 771
RR + S+ G ++ + + +GEGTY VYK K K T LVALK++RL++E EG P TA
Sbjct: 156 RRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTA 214
Query: 772 IREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHF 831
IRE+ +L+ L H ++V + +I+ ++ + LVFEY+D DL L+
Sbjct: 215 IREVSLLKDLKHANIVTLHDIIHTEK----------SLTLVFEYLDKDLKQYLDDCGNII 264
Query: 832 SEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRP 891
+ ++K F+ QL+ GL YCH++ LHRD+K N+L+N G++KLADFGLAR S ++
Sbjct: 265 NMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA-KSIPTKT 323
Query: 892 YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRL 951
Y+N+V+TLWYRPP++LLG Y+ ID+W GCI E+ T +P+F + QL I R+
Sbjct: 324 YSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRI 383
Query: 952 CGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTA 1011
G+P WP ++ F T K L + S DLL +L + R +A
Sbjct: 384 LGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISA 443
Query: 1012 EQTLQSDF 1019
E ++ F
Sbjct: 444 EDAMKHPF 451
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 215 bits (548), Expect = 2e-55
Identities = 118/308 (38%), Positives = 177/308 (57%), Gaps = 12/308 (3%)
Query: 712 RRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITA 771
RR + S+ G ++ + + +GEGTY VYK K K T LVALK++RL++E EG P TA
Sbjct: 150 RRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTA 208
Query: 772 IREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHF 831
IRE+ +L+ L H ++V + +I+ ++ + LVFEY+D DL L+
Sbjct: 209 IREVSLLKDLKHANIVTLHDIIHTEK----------SLTLVFEYLDKDLKQYLDDCGNII 258
Query: 832 SEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRP 891
+ ++K F+ QL+ GL YCH++ LHRD+K N+L+N G++KLADFGLAR S ++
Sbjct: 259 NMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA-KSIPTKT 317
Query: 892 YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRL 951
Y+N+V+TLWYRPP++LLG Y+ ID+W GCI E+ T +P+F + QL I R+
Sbjct: 318 YSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRI 377
Query: 952 CGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTA 1011
G+P WP ++ F T K L + S DLL +L + R +A
Sbjct: 378 LGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISA 437
Query: 1012 EQTLQSDF 1019
E ++ F
Sbjct: 438 EDAMKHPF 445
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 213 bits (541), Expect = 1e-54
Identities = 135/397 (34%), Positives = 206/397 (51%), Gaps = 23/397 (5%)
Query: 628 PPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELPGGDLSPPDSPE 687
PP P D + P + P ++ + QR R + D+ LP P + +
Sbjct: 54 PPQECSTFSPTDSG-EEPGQLSPGVQFQRRQNQR-RFSMEDVSKRLSLPMDIRLPQEFLQ 111
Query: 688 PKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDK 747
+ P P K ++ RR + SD G ++ + + +GEGTY V+K + K
Sbjct: 112 KLQMESPDLP-KPLSRM------SRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSK 164
Query: 748 DTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIV-TDKQDALDFKKDK 806
T LVALK++RL++E EG P TAIRE+ +L+ L H ++V + +++ TD+
Sbjct: 165 LTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDR---------- 213
Query: 807 GAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNIL 866
+ LVFEY+D DL L+ S ++K FM QL+ GL YCH + LHRD+K N+L
Sbjct: 214 -SLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLL 272
Query: 867 LNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCIL 926
+N G++KLADFGLAR S ++ Y+N+V+TLWYRPP++LLG Y+ ID+W GCI
Sbjct: 273 INERGELKLADFGLARA-KSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIH 331
Query: 927 GELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEF 986
E+ T +P+F + +L LI RL G+P WP V F T + L
Sbjct: 332 YEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHA 391
Query: 987 SFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV 1023
+ + + LL +L + R +AE L + + +
Sbjct: 392 PRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSL 428
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 213 bits (541), Expect = 1e-54
Identities = 135/397 (34%), Positives = 206/397 (51%), Gaps = 23/397 (5%)
Query: 628 PPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELPGGDLSPPDSPE 687
PP P D + P + P ++ + QR R + D+ LP P + +
Sbjct: 54 PPQECSTFSPTDSG-EEPGQLSPGVQFQRRQNQR-RFSMEDVSKRLSLPMDIRLPQEFLQ 111
Query: 688 PKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDK 747
+ P P K ++ RR + SD G ++ + + +GEGTY V+K + K
Sbjct: 112 KLQMESPDLP-KPLSRM------SRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSK 164
Query: 748 DTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIV-TDKQDALDFKKDK 806
T LVALK++RL++E EG P TAIRE+ +L+ L H ++V + +++ TD+
Sbjct: 165 LTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDR---------- 213
Query: 807 GAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNIL 866
+ LVFEY+D DL L+ S ++K FM QL+ GL YCH + LHRD+K N+L
Sbjct: 214 -SLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLL 272
Query: 867 LNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCIL 926
+N G++KLADFGLAR S ++ Y+N+V+TLWYRPP++LLG Y+ ID+W GCI
Sbjct: 273 INERGELKLADFGLARA-KSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIH 331
Query: 927 GELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEF 986
E+ T +P+F + +L LI RL G+P WP V F T + L
Sbjct: 332 YEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHA 391
Query: 987 SFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV 1023
+ + + LL +L + R +AE L + + +
Sbjct: 392 PRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSL 428
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 211 bits (537), Expect = 4e-54
Identities = 119/313 (38%), Positives = 178/313 (56%), Gaps = 14/313 (4%)
Query: 712 RRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITA 771
RR + SD G ++ + + +GEGTY V+K + K T LVALK++RL++E EG P TA
Sbjct: 159 RRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTA 217
Query: 772 IREIKILRQLIHRSVVNMKEIV-TDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH 830
IRE+ +L+ L H ++V + +++ TD+ + LVFEY+D DL L+
Sbjct: 218 IREVSLLKNLKHANIVTLHDLIHTDR-----------SLTLVFEYLDSDLKQYLDHCGNL 266
Query: 831 FSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESR 890
S ++K FM QL+ GL YCH + LHRD+K N+L+N G++KLADFGLAR S ++
Sbjct: 267 MSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARA-KSVPTK 325
Query: 891 PYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISR 950
Y+N+V+TLWYRPP++LLG Y+ ID+W GCI E+ T +P+F + +L LI R
Sbjct: 326 TYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 385
Query: 951 LCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCT 1010
L G+P WP V F T + L + + + LL +L + R +
Sbjct: 386 LLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMS 445
Query: 1011 AEQTLQSDFLKDV 1023
AE L + + +
Sbjct: 446 AEAALSHSYFRSL 458
>gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens]
Length = 289
Score = 206 bits (525), Expect = 1e-52
Identities = 109/278 (39%), Positives = 158/278 (56%), Gaps = 11/278 (3%)
Query: 760 LDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHD 819
+D EK+G PI+++REI +L +L H ++V +KE+V + +LV Y + D
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNH--------LESIFLVMGYCEQD 52
Query: 820 LMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFG 879
L LLE+ FSE +K + Q++ GL+Y H+ +HRD+K SN+L+ + G +K ADFG
Sbjct: 53 LASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFG 112
Query: 880 LARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQAN 939
LAR Y +P T KV+TLWYR PELLLG T +ID+W+ GCIL EL +P+
Sbjct: 113 LARAYGVPV-KPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGT 171
Query: 940 LELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDH 999
E+ Q++LI +L G+P +WP KLP +KQ L+ +F ++ A L LL
Sbjct: 172 SEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHF 231
Query: 1000 MLTLDPSKRCTAEQTLQSDFLKDVEL--SKMAPPDLPH 1035
+ DP KR TA L+S + K+ L P PH
Sbjct: 232 LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPH 269
>gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens]
Length = 272
Score = 206 bits (523), Expect = 2e-52
Identities = 106/266 (39%), Positives = 155/266 (58%), Gaps = 9/266 (3%)
Query: 760 LDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHD 819
+D EK+G PI+++REI +L +L H ++V +KE+V + +LV Y + D
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNH--------LESIFLVMGYCEQD 52
Query: 820 LMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFG 879
L LLE+ FSE +K + Q++ GL+Y H+ +HRD+K SN+L+ + G +K ADFG
Sbjct: 53 LASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFG 112
Query: 880 LARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQAN 939
LAR Y +P T KV+TLWYR PELLLG T +ID+W+ GCIL EL +P+
Sbjct: 113 LARAYGVPV-KPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGT 171
Query: 940 LELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDH 999
E+ Q++LI +L G+P +WP KLP +KQ L+ +F ++ A L LL
Sbjct: 172 SEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHF 231
Query: 1000 MLTLDPSKRCTAEQTLQSDFLKDVEL 1025
+ DP KR TA L+S + K+ L
Sbjct: 232 LFMYDPKKRATAGDCLESSYFKEKPL 257
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 204 bits (519), Expect = 5e-52
Identities = 133/390 (34%), Positives = 202/390 (51%), Gaps = 25/390 (6%)
Query: 638 GDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAIT-PPQQ 696
G D + P +T+P KK + QRT+ P E P + S I
Sbjct: 36 GMDSVIKPLDTIPED--KKVRVQRTQSTFD----PFEKPANQVKRVHSENNACINFKTSS 89
Query: 697 PYKKRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALK 756
K+ PK+ T +GK D ++ + +GEG+Y VYK K K G+LVALK
Sbjct: 90 TGKESPKVR-RHSSPSSPTSPKFGK--ADSYEKLEKLGEGSYATVYKGKSKVNGKLVALK 146
Query: 757 KVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYM 816
+RL E+EG P TAIRE +L+ L H ++V + +I+ K+ LVFEY+
Sbjct: 147 VIRLQ-EEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKE----------TLTLVFEYV 195
Query: 817 DHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLA 876
DL ++ D++K F+ QL+ GL Y H++ LHRD+K N+L++++G++KLA
Sbjct: 196 HTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLA 255
Query: 877 DFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF 936
DFGLAR S S Y+N+V+TLWYRPP++LLG Y+ +D+W GCI E+ F
Sbjct: 256 DFGLARA-KSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAF 314
Query: 937 QANLELA-QLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIP--SAA 993
++ QLE I + G+P WP V LP+F + + LR+ ++ + + A
Sbjct: 315 PGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHA 374
Query: 994 LDLLDHMLTLDPSKRCTAEQTLQSDFLKDV 1023
DL +L P R +A+ L ++ D+
Sbjct: 375 EDLASKLLQCSPKNRLSAQAALSHEYFSDL 404
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 203 bits (517), Expect = 9e-52
Identities = 110/300 (36%), Positives = 173/300 (57%), Gaps = 16/300 (5%)
Query: 726 KFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNE---KEGFPITAIREIKILRQLI 782
+++ + +GEG + VYKA+DK+T ++VA+KK++L + K+G TA+REIK+L++L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 783 HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842
H +++ + LD K LVF++M+ DL +++ + + HIK++M
Sbjct: 71 HPNIIGL----------LDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM 120
Query: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
++GLEY H+ LHRD+K +N+LL+ +G +KLADFGLA+ + S +R YT++V+T WYR
Sbjct: 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSP-NRAYTHQVVTRWYR 179
Query: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
PELL G Y +D+W+ GCIL EL + P + +L QL I G+P WPD
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPD 239
Query: 963 VIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
+ LP + T K L FS LDL+ + +P R TA Q L+ + +
Sbjct: 240 MCSLPDYVTFKSFPGI--PLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,986,118
Number of Sequences: 37866
Number of extensions: 4573268
Number of successful extensions: 109310
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1708
Number of HSP's successfully gapped in prelim test: 2052
Number of HSP's that attempted gapping in prelim test: 31488
Number of HSP's gapped (non-prelim): 37180
length of query: 1490
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1375
effective length of database: 13,892,928
effective search space: 19102776000
effective search space used: 19102776000
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.