Search of human proteins with 157388955

Search of human proteins with 157388955

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157388955 schlafen family member 12 [Homo sapiens]
         (578 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157388955 schlafen family member 12 [Homo sapiens]                1167   0.0  
gi|222537745 schlafen family member 12-like [Homo sapiens]            842   0.0  
gi|145580600 schlafen family member 5 [Homo sapiens]                  453   e-127
gi|193788705 schlafen family member 14 [Homo sapiens]                 434   e-121
gi|56119108 schlafen family member 13 [Homo sapiens]                  377   e-104
gi|157388965 schlafen family member 11 [Homo sapiens]                 362   e-100
gi|157388963 schlafen family member 11 [Homo sapiens]                 362   e-100
gi|157388961 schlafen family member 11 [Homo sapiens]                 362   e-100
gi|157388959 schlafen family member 11 [Homo sapiens]                 362   e-100
gi|157388957 schlafen family member 11 [Homo sapiens]                 362   e-100
gi|45267821 schlafen-like 1 [Homo sapiens]                             37   0.050
gi|27477134 nucleoporin 210 [Homo sapiens]                             35   0.14 
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s...    33   0.55 
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs...    33   0.55 
gi|195947369 junction-mediating and regulatory protein [Homo sap...    33   0.94 
gi|197313732 pleckstrin homology-like domain, family B, member 2...    33   0.94 
gi|197313730 pleckstrin homology-like domain, family B, member 2...    33   0.94 
gi|197313728 pleckstrin homology-like domain, family B, member 2...    33   0.94 
gi|21955172 pleckstrin homology-like domain, family B, member 2 ...    33   0.94 
gi|110618253 mitochondrial DNA-directed RNA polymerase precursor...    31   2.7  
gi|45827771 autoantigen RCD8 [Homo sapiens]                            31   2.7  
gi|169169319 PREDICTED: hypothetical protein LOC285754 [Homo sap...    30   6.1  
gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens]        30   6.1  
gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens]      30   6.1  

>gi|157388955 schlafen family member 12 [Homo sapiens]
          Length = 578

 Score = 1167 bits (3020), Expect = 0.0
 Identities = 578/578 (100%), Positives = 578/578 (100%)

Query: 1   MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIK 60
           MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIK
Sbjct: 1   MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIK 60

Query: 61  AEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRIT 120
           AEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRIT
Sbjct: 61  AEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRIT 120

Query: 121 TLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKAL 180
           TLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKAL
Sbjct: 121 TLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKAL 180

Query: 181 AGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIG 240
           AGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIG
Sbjct: 181 AGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIG 240

Query: 241 LNEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCG 300
           LNEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCG
Sbjct: 241 LNEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCG 300

Query: 301 YVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQIN 360
           YVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQIN
Sbjct: 301 YVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQIN 360

Query: 361 TSLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKG 420
           TSLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKG
Sbjct: 361 TSLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKG 420

Query: 421 SLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQK 480
           SLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQK
Sbjct: 421 SLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQK 480

Query: 481 LAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKR 540
           LAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKR
Sbjct: 481 LAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKR 540

Query: 541 LKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT 578
           LKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT
Sbjct: 541 LKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT 578


>gi|222537745 schlafen family member 12-like [Homo sapiens]
          Length = 617

 Score =  842 bits (2176), Expect = 0.0
 Identities = 430/568 (75%), Positives = 475/568 (83%), Gaps = 10/568 (1%)

Query: 1   MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIK 60
           MNIS+DL+TNYAELVL+VGRVTLGEN+RKKMKDC+LRK+QNE+VSRA+CALLNSGGGVIK
Sbjct: 48  MNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIK 107

Query: 61  AEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRIT 120
           AE+EN+ YSY KDGIGLDLENSFSN+L FVP +LDFMQNGNYF IFVKSWSL TSG +I 
Sbjct: 108 AEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIA 167

Query: 121 TLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKAL 180
           TLSS+LYKRD+TSAKVMNA+AALEFLKDM+KT GR YLRPE  AKR CVD+QEE+NM+AL
Sbjct: 168 TLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEAL 227

Query: 181 AGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIG 240
           A  FF+RTEL  KEKLTFTESTHVEIKNFSTEKLLQRI EILPQYVSAFANTDGGYLF+G
Sbjct: 228 AADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVG 287

Query: 241 LNEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCG 300
           LNEDKE+IGFKAE S L  LE   + SI K+PVHHFC+EK  INY CKFLGVYDKG LCG
Sbjct: 288 LNEDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCG 347

Query: 301 YVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQIN 360
           YV ALRVERFCCAVFAK+PDSWHVKDNRV QLT KEWIQFMV++EP      EE+ S  +
Sbjct: 348 YVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP----VCEELPSPAS 403

Query: 361 TSLPAPHSWPLLEW-----QRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMD 415
           TS P   S+PL E+     Q  R+H PGLS +IT  P+  CR LF QHEGLKQLICEEM 
Sbjct: 404 TSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMG 463

Query: 416 SVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTAL 475
           SV KGSLIFSRSWS+DLGLQENHKVLCDALLISQD PPVLYTFHMVQDEEFK YSTQTA 
Sbjct: 464 SVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQ 523

Query: 476 TLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALF 535
           TLKQKLAKIGGYTKKVCVMTKIFYLSPEG TSCQYDL SQVIYPESYY+T  +  +K L 
Sbjct: 524 TLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQ-TMKDLE 582

Query: 536 KALKRLKSLRDQFSFAENLYQIIGIDCF 563
           KAL  +    +Q      L++     C+
Sbjct: 583 KALSNILPKENQIFLFVCLFRFCLFVCW 610


>gi|145580600 schlafen family member 5 [Homo sapiens]
          Length = 891

 Score =  453 bits (1166), Expect = e-127
 Identities = 251/546 (45%), Positives = 351/546 (64%), Gaps = 21/546 (3%)

Query: 1   MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIK 60
           M++ +D++TN+ E V+D G+VTLG   R++M D +LR+KQNE + RA+CALLNSGGG+IK
Sbjct: 1   MSLRIDVDTNFPECVVDAGKVTLGTQQRQEM-DPRLREKQNEIILRAVCALLNSGGGIIK 59

Query: 61  AEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRIT 120
           AEIEN+ Y+Y + G+GLD+   F +       +LD MQ  N+FLIFVKSW+   +G+ + 
Sbjct: 60  AEIENKGYNYERHGVGLDVPPIFRS-------HLDKMQKENHFLIFVKSWNTE-AGVPLA 111

Query: 121 TLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKAL 180
           TL SNLY R+ TS  VM++  AL FLK   +T   + +   L  +     +Q E N+   
Sbjct: 112 TLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS 171

Query: 181 AGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIG 240
           A   FDR  L   EKL   ESTHVE   FST+ +   +K+ LP+ VSAFANT+GGY+F G
Sbjct: 172 AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYVFFG 230

Query: 241 LNEDK-EIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLC 299
           ++++  ++IG + E  DL  L   I+  I+K+PVHHFC ++ +I Y   FL V+DKG+L 
Sbjct: 231 VHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALR 290

Query: 300 GYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQI 359
           GYVCA++VE+FCCAVFAK P SW VKDNRV QL  +EW  +M+EA+P  S    E++ Q+
Sbjct: 291 GYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRC-PEMVLQL 349

Query: 360 NTSLPAPHSWPLLEW-------QRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICE 412
           + S   P S P+          ++Q+ + P  S R+ YTPE+L ++LF QH+GL+ LI  
Sbjct: 350 SLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINT 409

Query: 413 EMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQ 472
           EM    +G LIFS+SW+VDLGLQE   V+CDALLISQ++ P+LYT     D   KGYS  
Sbjct: 410 EMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMI 469

Query: 473 TALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLK 532
            A +LKQKL   GGYT ++C+   +  L+ +      Y    Q IYPESY F   ++ ++
Sbjct: 470 VAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQ-IYPESYNFMTPQH-ME 527

Query: 533 ALFKAL 538
           AL ++L
Sbjct: 528 ALLQSL 533


>gi|193788705 schlafen family member 14 [Homo sapiens]
          Length = 912

 Score =  434 bits (1116), Expect = e-121
 Identities = 246/540 (45%), Positives = 344/540 (63%), Gaps = 28/540 (5%)

Query: 2   NISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKA 61
           ++  D E  Y E+++DVGRV  GE +RKKM +  L++ +N  + RA+CALLNSGGGVIKA
Sbjct: 3   SLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKA 62

Query: 62  EIENEDYSYTKDGIGLDLENSFSNILLFVPE-YLDFMQNGNYFLIFVKSWSLNTSGL--R 118
           EI+++ YSY   G+G DLE SF  +L    + YLD+MQ G+  LIFVKSWS +   L  R
Sbjct: 63  EIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLR 122

Query: 119 ITTLSSNLYKRDITSAKVMNATAALEFLKD--MKKTRGR---LYLRPELLAKRPCVDIQE 173
           I +L SNLY+RD+TSA  ++A++ALE L++   +  RGR     L P+ +  R C  IQE
Sbjct: 123 ICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNR-C--IQE 179

Query: 174 ENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTD 233
           E +M+ LA  FF + +L  KEKL FTESTHVE K F+T+K++ RIKE+LP YVSAFANT 
Sbjct: 180 EEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQ 239

Query: 234 GGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGV 292
           GGY+ IG+++  KE++G K E  + D L++EIE  I K+P  HFC EK K+N++ K L V
Sbjct: 240 GGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNV 299

Query: 293 YDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVE---AEPKFS 349
           Y K  L GYVC ++VE FCC VFA+ PDSW +KDN V +LT ++W+  M++   A P   
Sbjct: 300 YQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLV 359

Query: 350 SSYEEVISQINTSLPAPHSWPL----LEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEG 405
           + Y   +    +S      +P+     +   QRH  P     + + PE+LC+KLF  H+ 
Sbjct: 360 TDYNSCLISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKE 419

Query: 406 LKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEE 465
           L+ L+   +    +G +IFSRSW+ D+G ++   VLCDALLI+ +SP VLYT  ++ D  
Sbjct: 420 LEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYT--ILIDPN 477

Query: 466 FKG---YSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESY 522
           + G   Y+  TA  LKQKL  +GGYT KVC++ ++ +LS       +  LR    YP SY
Sbjct: 478 WPGGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLR----YPRSY 533


>gi|56119108 schlafen family member 13 [Homo sapiens]
          Length = 897

 Score =  377 bits (967), Expect = e-104
 Identities = 227/565 (40%), Positives = 334/565 (59%), Gaps = 31/565 (5%)

Query: 4   SVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEI 63
           S+ +  +Y +LV+DVG VTLGE +RKK++  + R ++   V RA CALLNSGGGVI+ E+
Sbjct: 7   SLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQ-RDQERARVIRAACALLNSGGGVIQMEM 65

Query: 64  ENEDYSYTKDGIGLDLENSFSNILLF--VPEYLDFMQNGNYFLIFVKSWSLN------TS 115
            N D   T+  +GLDLE S   ++ +  +  + +  Q+G  F IFVKSWS +      + 
Sbjct: 66  ANRDERPTE--MGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSF 123

Query: 116 GLRITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLR----PELLAKRPCVDI 171
             RI +LSS+LY R  TS   MN+  A +FLK  ++      +     P  + K    +I
Sbjct: 124 NSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVYQNI 183

Query: 172 QEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFAN 231
            E N     A   F    ++  E L+F ES  +E K FST+ + Q ++ I+P+Y+SAFAN
Sbjct: 184 SESNP----AYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFAN 239

Query: 232 TDGGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFL 290
           T+GGYLFIG+++  ++++G   E  D D L+  I ++I K+P+ HFC  K ++ YS K +
Sbjct: 240 TEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIV 299

Query: 291 GVYDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSS 350
            V+    L GY+C ++V+ FCC VF++ P SW V++  +  LT +EW++ M++A+P+F  
Sbjct: 300 EVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPP 359

Query: 351 SYEEVI-SQINTSLPAPHSWPL-----LEWQR--QRHHCPGLSGRITYTPENLCRKLFLQ 402
            + E   SQ++ S       P+     LE +   Q+H  P   G +  TPE+L ++L LQ
Sbjct: 360 DFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQ 419

Query: 403 HEGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQ 462
           HEGLK+LI ++M    +G +I SRSW+VDL LQE   V+CDALLI+Q+S P+LYT    Q
Sbjct: 420 HEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQ 479

Query: 463 DEEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESY 522
           D E + Y T+TA TLKQKL  +GGYT KVCV  K+  LSPE          S + YP SY
Sbjct: 480 DAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASY 539

Query: 523 YFTRRKY---LLKALFKALKRLKSL 544
                ++   LL++L   L   +SL
Sbjct: 540 SLAGTQHMEALLQSLVIVLLGFRSL 564


>gi|157388965 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score =  362 bits (930), Expect = e-100
 Identities = 225/564 (39%), Positives = 322/564 (57%), Gaps = 35/564 (6%)

Query: 7   LETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENE 66
           +E +Y +LV++VG VTLGE +RKK++  + R ++ E V RA CALLNSGGGVI+   + E
Sbjct: 10  VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMAKKVE 68

Query: 67  DYSYTKDGIGLDLENSFSNILLF--VPEYLDFMQNGNYFLIFVKSWSLN------TSGLR 118
                   +GLDLE S   ++    +  + +  Q G  F IFVKSWS        +   R
Sbjct: 69  H----PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124

Query: 119 ITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTR----GRLY-LRPELLAKRPCVDIQE 173
           + +LSS+LY+R  TS + M++  A  FLK  +K +    G  + +   +  + P  D  +
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKILEEGPFHKIHKGVYQELPNSDPAD 184

Query: 174 ENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTD 233
            N+  A   + F +  L+  E L F ES  VE K FST+   + +K  +P+YV AFANT 
Sbjct: 185 PNSDPA--DLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTG 242

Query: 234 GGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGV 292
           GGYLFIG+++  +E++G   E  D D L R+IE++I K+P  HFC  ++ I ++ K + V
Sbjct: 243 GGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNV 302

Query: 293 YDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSY 352
             +G L GY C +RV  FCCAVF++ P+SW V+D  V  LT ++W+  M + +P      
Sbjct: 303 LKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLS 362

Query: 353 EEVISQINTSLPAPHSWPLL---------EWQRQRHHCPGLSGRITYTPENLCRKLFLQH 403
           E+   Q++ S   P S P+          E Q+     P   G + YTPE+L R L  +H
Sbjct: 363 EDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVP--PGYLRYTPESLWRDLISEH 420

Query: 404 EGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQD 463
            GL++LI ++M    +G LIFSRSW+VDL LQE   V+CDALLI+Q+S P+LYT    QD
Sbjct: 421 RGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD 480

Query: 464 EEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYY 523
            E + Y T+TA TLKQKL  +GGYT KVCV  K+  LSPE          S + YP SY 
Sbjct: 481 AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS 540

Query: 524 FTRRKY---LLKALFKALKRLKSL 544
               ++   LL++L   L   +SL
Sbjct: 541 LAGTQHMEALLQSLVIVLLGFRSL 564


>gi|157388963 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score =  362 bits (930), Expect = e-100
 Identities = 225/564 (39%), Positives = 322/564 (57%), Gaps = 35/564 (6%)

Query: 7   LETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENE 66
           +E +Y +LV++VG VTLGE +RKK++  + R ++ E V RA CALLNSGGGVI+   + E
Sbjct: 10  VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMAKKVE 68

Query: 67  DYSYTKDGIGLDLENSFSNILLF--VPEYLDFMQNGNYFLIFVKSWSLN------TSGLR 118
                   +GLDLE S   ++    +  + +  Q G  F IFVKSWS        +   R
Sbjct: 69  H----PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124

Query: 119 ITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTR----GRLY-LRPELLAKRPCVDIQE 173
           + +LSS+LY+R  TS + M++  A  FLK  +K +    G  + +   +  + P  D  +
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKILEEGPFHKIHKGVYQELPNSDPAD 184

Query: 174 ENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTD 233
            N+  A   + F +  L+  E L F ES  VE K FST+   + +K  +P+YV AFANT 
Sbjct: 185 PNSDPA--DLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTG 242

Query: 234 GGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGV 292
           GGYLFIG+++  +E++G   E  D D L R+IE++I K+P  HFC  ++ I ++ K + V
Sbjct: 243 GGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNV 302

Query: 293 YDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSY 352
             +G L GY C +RV  FCCAVF++ P+SW V+D  V  LT ++W+  M + +P      
Sbjct: 303 LKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLS 362

Query: 353 EEVISQINTSLPAPHSWPLL---------EWQRQRHHCPGLSGRITYTPENLCRKLFLQH 403
           E+   Q++ S   P S P+          E Q+     P   G + YTPE+L R L  +H
Sbjct: 363 EDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVP--PGYLRYTPESLWRDLISEH 420

Query: 404 EGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQD 463
            GL++LI ++M    +G LIFSRSW+VDL LQE   V+CDALLI+Q+S P+LYT    QD
Sbjct: 421 RGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD 480

Query: 464 EEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYY 523
            E + Y T+TA TLKQKL  +GGYT KVCV  K+  LSPE          S + YP SY 
Sbjct: 481 AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS 540

Query: 524 FTRRKY---LLKALFKALKRLKSL 544
               ++   LL++L   L   +SL
Sbjct: 541 LAGTQHMEALLQSLVIVLLGFRSL 564


>gi|157388961 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score =  362 bits (930), Expect = e-100
 Identities = 225/564 (39%), Positives = 322/564 (57%), Gaps = 35/564 (6%)

Query: 7   LETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENE 66
           +E +Y +LV++VG VTLGE +RKK++  + R ++ E V RA CALLNSGGGVI+   + E
Sbjct: 10  VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMAKKVE 68

Query: 67  DYSYTKDGIGLDLENSFSNILLF--VPEYLDFMQNGNYFLIFVKSWSLN------TSGLR 118
                   +GLDLE S   ++    +  + +  Q G  F IFVKSWS        +   R
Sbjct: 69  H----PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124

Query: 119 ITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTR----GRLY-LRPELLAKRPCVDIQE 173
           + +LSS+LY+R  TS + M++  A  FLK  +K +    G  + +   +  + P  D  +
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKILEEGPFHKIHKGVYQELPNSDPAD 184

Query: 174 ENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTD 233
            N+  A   + F +  L+  E L F ES  VE K FST+   + +K  +P+YV AFANT 
Sbjct: 185 PNSDPA--DLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTG 242

Query: 234 GGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGV 292
           GGYLFIG+++  +E++G   E  D D L R+IE++I K+P  HFC  ++ I ++ K + V
Sbjct: 243 GGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNV 302

Query: 293 YDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSY 352
             +G L GY C +RV  FCCAVF++ P+SW V+D  V  LT ++W+  M + +P      
Sbjct: 303 LKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLS 362

Query: 353 EEVISQINTSLPAPHSWPLL---------EWQRQRHHCPGLSGRITYTPENLCRKLFLQH 403
           E+   Q++ S   P S P+          E Q+     P   G + YTPE+L R L  +H
Sbjct: 363 EDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVP--PGYLRYTPESLWRDLISEH 420

Query: 404 EGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQD 463
            GL++LI ++M    +G LIFSRSW+VDL LQE   V+CDALLI+Q+S P+LYT    QD
Sbjct: 421 RGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD 480

Query: 464 EEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYY 523
            E + Y T+TA TLKQKL  +GGYT KVCV  K+  LSPE          S + YP SY 
Sbjct: 481 AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS 540

Query: 524 FTRRKY---LLKALFKALKRLKSL 544
               ++   LL++L   L   +SL
Sbjct: 541 LAGTQHMEALLQSLVIVLLGFRSL 564


>gi|157388959 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score =  362 bits (930), Expect = e-100
 Identities = 225/564 (39%), Positives = 322/564 (57%), Gaps = 35/564 (6%)

Query: 7   LETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENE 66
           +E +Y +LV++VG VTLGE +RKK++  + R ++ E V RA CALLNSGGGVI+   + E
Sbjct: 10  VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMAKKVE 68

Query: 67  DYSYTKDGIGLDLENSFSNILLF--VPEYLDFMQNGNYFLIFVKSWSLN------TSGLR 118
                   +GLDLE S   ++    +  + +  Q G  F IFVKSWS        +   R
Sbjct: 69  H----PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124

Query: 119 ITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTR----GRLY-LRPELLAKRPCVDIQE 173
           + +LSS+LY+R  TS + M++  A  FLK  +K +    G  + +   +  + P  D  +
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKILEEGPFHKIHKGVYQELPNSDPAD 184

Query: 174 ENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTD 233
            N+  A   + F +  L+  E L F ES  VE K FST+   + +K  +P+YV AFANT 
Sbjct: 185 PNSDPA--DLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTG 242

Query: 234 GGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGV 292
           GGYLFIG+++  +E++G   E  D D L R+IE++I K+P  HFC  ++ I ++ K + V
Sbjct: 243 GGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNV 302

Query: 293 YDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSY 352
             +G L GY C +RV  FCCAVF++ P+SW V+D  V  LT ++W+  M + +P      
Sbjct: 303 LKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLS 362

Query: 353 EEVISQINTSLPAPHSWPLL---------EWQRQRHHCPGLSGRITYTPENLCRKLFLQH 403
           E+   Q++ S   P S P+          E Q+     P   G + YTPE+L R L  +H
Sbjct: 363 EDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVP--PGYLRYTPESLWRDLISEH 420

Query: 404 EGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQD 463
            GL++LI ++M    +G LIFSRSW+VDL LQE   V+CDALLI+Q+S P+LYT    QD
Sbjct: 421 RGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD 480

Query: 464 EEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYY 523
            E + Y T+TA TLKQKL  +GGYT KVCV  K+  LSPE          S + YP SY 
Sbjct: 481 AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS 540

Query: 524 FTRRKY---LLKALFKALKRLKSL 544
               ++   LL++L   L   +SL
Sbjct: 541 LAGTQHMEALLQSLVIVLLGFRSL 564


>gi|157388957 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score =  362 bits (930), Expect = e-100
 Identities = 225/564 (39%), Positives = 322/564 (57%), Gaps = 35/564 (6%)

Query: 7   LETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENE 66
           +E +Y +LV++VG VTLGE +RKK++  + R ++ E V RA CALLNSGGGVI+   + E
Sbjct: 10  VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMAKKVE 68

Query: 67  DYSYTKDGIGLDLENSFSNILLF--VPEYLDFMQNGNYFLIFVKSWSLN------TSGLR 118
                   +GLDLE S   ++    +  + +  Q G  F IFVKSWS        +   R
Sbjct: 69  H----PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124

Query: 119 ITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTR----GRLY-LRPELLAKRPCVDIQE 173
           + +LSS+LY+R  TS + M++  A  FLK  +K +    G  + +   +  + P  D  +
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKILEEGPFHKIHKGVYQELPNSDPAD 184

Query: 174 ENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTD 233
            N+  A   + F +  L+  E L F ES  VE K FST+   + +K  +P+YV AFANT 
Sbjct: 185 PNSDPA--DLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTG 242

Query: 234 GGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGV 292
           GGYLFIG+++  +E++G   E  D D L R+IE++I K+P  HFC  ++ I ++ K + V
Sbjct: 243 GGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNV 302

Query: 293 YDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSY 352
             +G L GY C +RV  FCCAVF++ P+SW V+D  V  LT ++W+  M + +P      
Sbjct: 303 LKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLS 362

Query: 353 EEVISQINTSLPAPHSWPLL---------EWQRQRHHCPGLSGRITYTPENLCRKLFLQH 403
           E+   Q++ S   P S P+          E Q+     P   G + YTPE+L R L  +H
Sbjct: 363 EDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVP--PGYLRYTPESLWRDLISEH 420

Query: 404 EGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQD 463
            GL++LI ++M    +G LIFSRSW+VDL LQE   V+CDALLI+Q+S P+LYT    QD
Sbjct: 421 RGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD 480

Query: 464 EEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYY 523
            E + Y T+TA TLKQKL  +GGYT KVCV  K+  LSPE          S + YP SY 
Sbjct: 481 AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS 540

Query: 524 FTRRKY---LLKALFKALKRLKSL 544
               ++   LL++L   L   +SL
Sbjct: 541 LAGTQHMEALLQSLVIVLLGFRSL 564


>gi|45267821 schlafen-like 1 [Homo sapiens]
          Length = 407

 Score = 37.0 bits (84), Expect = 0.050
 Identities = 19/60 (31%), Positives = 32/60 (53%)

Query: 199 TESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLNEDKEIIGFKAEMSDLD 258
           +E+ ++E K  S E L    K  + +YV AF N++GG L +G+ +   + G +    D D
Sbjct: 220 SETRNMEFKRGSGEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIRCSHRDED 279


>gi|27477134 nucleoporin 210 [Homo sapiens]
          Length = 1887

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 14/97 (14%)

Query: 122 LSSNLYKRDITSAKVMNATAALEFLKDMK--KTRGRLYLRPELLAKRPCVDIQEENNMKA 179
           L+S ++  DIT+ +V+   A ++ + D++   T   LYL    L  +      E N    
Sbjct: 92  LTSIIFAEDITTGQVLRCDAIVDLIHDIQIVSTTRELYLEDSPLELKIQALDSEGNTFST 151

Query: 180 LAGVFFDRT-----ELDRKEK-------LTFTESTHV 204
           LAG+ F+ T     E DR          LTF EST++
Sbjct: 152 LAGLVFEWTIVKDSEADRFSDSHNALRILTFLESTYI 188


>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
           sapiens]
          Length = 451

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 33/141 (23%), Positives = 54/141 (38%), Gaps = 14/141 (9%)

Query: 414 MDSVRKGSLIFSRSWSVDLGLQENHKVLC------DALLISQDSPPVLYTFHMVQDEEFK 467
           M+ +R  +L+ S+ W+ D       K +       + LL  QD   +LYT  +    E  
Sbjct: 108 MNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECP 167

Query: 468 GYSTQTALTLKQKLAKIGGYTKKVCVMTKIF--------YLSPEGMTSCQYDLRSQVIYP 519
            +     +       K G Y      +T I+         ++P+G    QYDL  Q I  
Sbjct: 168 MHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGK 227

Query: 520 ESYYFTRRKYLLKALFKALKR 540
           E+   +  +Y +      LKR
Sbjct: 228 ETIKSSTGEYTVMTAHFHLKR 248


>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
           [Homo sapiens]
          Length = 451

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 33/141 (23%), Positives = 54/141 (38%), Gaps = 14/141 (9%)

Query: 414 MDSVRKGSLIFSRSWSVDLGLQENHKVLC------DALLISQDSPPVLYTFHMVQDEEFK 467
           M+ +R  +L+ S+ W+ D       K +       + LL  QD   +LYT  +    E  
Sbjct: 108 MNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECP 167

Query: 468 GYSTQTALTLKQKLAKIGGYTKKVCVMTKIF--------YLSPEGMTSCQYDLRSQVIYP 519
            +     +       K G Y      +T I+         ++P+G    QYDL  Q I  
Sbjct: 168 MHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGK 227

Query: 520 ESYYFTRRKYLLKALFKALKR 540
           E+   +  +Y +      LKR
Sbjct: 228 ETIKSSTGEYTVMTAHFHLKR 248


>gi|195947369 junction-mediating and regulatory protein [Homo
           sapiens]
          Length = 988

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 11/74 (14%)

Query: 504 GMTSCQYDLRSQVIY-----PESYYFT----RRKYLLKALFKALKRLKSLRDQFSFAENL 554
           G+ +C + + SQV++     PE YY +    R+K   + L +A KR++ L D+    E++
Sbjct: 296 GLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARKRIQELLDKHKNTESM 355

Query: 555 YQIIGIDCFQKNDK 568
            ++  +D +Q  D+
Sbjct: 356 VEL--LDLYQLEDE 367


>gi|197313732 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 188 TELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLNEDKEI 247
           +E  R ++L   E T + I N + E+L Q+IK+I  Q   +F   D     +   +  E 
Sbjct: 579 SEEQRSQELAAMEETRIVILN-NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSET 637

Query: 248 IGFKAEMSDLDDLER---EIEKSI 268
                E   LD L R   E+EK+I
Sbjct: 638 TELMKEKEILDHLNRKIAELEKNI 661


>gi|197313730 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 188 TELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLNEDKEI 247
           +E  R ++L   E T + I N + E+L Q+IK+I  Q   +F   D     +   +  E 
Sbjct: 579 SEEQRSQELAAMEETRIVILN-NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSET 637

Query: 248 IGFKAEMSDLDDLER---EIEKSI 268
                E   LD L R   E+EK+I
Sbjct: 638 TELMKEKEILDHLNRKIAELEKNI 661


>gi|197313728 pleckstrin homology-like domain, family B, member 2
           isoform b [Homo sapiens]
          Length = 1237

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 188 TELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLNEDKEI 247
           +E  R ++L   E T + I N + E+L Q+IK+I  Q   +F   D     +   +  E 
Sbjct: 606 SEEQRSQELAAMEETRIVILN-NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSET 664

Query: 248 IGFKAEMSDLDDLER---EIEKSI 268
                E   LD L R   E+EK+I
Sbjct: 665 TELMKEKEILDHLNRKIAELEKNI 688


>gi|21955172 pleckstrin homology-like domain, family B, member 2
           isoform c [Homo sapiens]
          Length = 1210

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 188 TELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLNEDKEI 247
           +E  R ++L   E T + I N + E+L Q+IK+I  Q   +F   D     +   +  E 
Sbjct: 579 SEEQRSQELAAMEETRIVILN-NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSET 637

Query: 248 IGFKAEMSDLDDLER---EIEKSI 268
                E   LD L R   E+EK+I
Sbjct: 638 TELMKEKEILDHLNRKIAELEKNI 661


>gi|110618253 mitochondrial DNA-directed RNA polymerase precursor
            [Homo sapiens]
          Length = 1230

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 6/98 (6%)

Query: 450  DSPPVLYTFHMVQDEEFKGYSTQTALTLKQKLAKIGGYTKKVC---VMTKIFYLSPEG-M 505
            D P  +Y+    Q E F+    Q  + + Q L   G  T+KV    VMT ++ ++  G  
Sbjct: 950  DVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLE--GFITRKVVKQTVMTVVYGVTRYGGR 1007

Query: 506  TSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRLKS 543
               +  LR    +P+ + +    YL++ +FK+L+ + S
Sbjct: 1008 LQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFS 1045


>gi|45827771 autoantigen RCD8 [Homo sapiens]
          Length = 1401

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 5/45 (11%)

Query: 366 PHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLI 410
           P  WP L WQ+QR         + ++ E L ++L  Q EGL+  +
Sbjct: 947 PEDWPALIWQQQRE-----LAELRHSQEELLQRLCTQLEGLQSTV 986


>gi|169169319 PREDICTED: hypothetical protein LOC285754 [Homo
           sapiens]
          Length = 1151

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 17/110 (15%)

Query: 29  KKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENEDYSYTKDGIGLD--LENSFSNI 86
           K MKD  L  KQNE+    +    ++ G + + +    +Y+ T   +GL+   + S  N 
Sbjct: 450 KNMKDDDLSMKQNENDLSQITLSQHADGPLKQIQETGYNYAMTLQLLGLEDGTDPSDRNP 509

Query: 87  LLFVPEYLDFMQNG---------------NYFLIFVKSWSLNTSGLRITT 121
           +L    YL F+                  NYF    ++ ++NTSGL + +
Sbjct: 510 VLMRGAYLSFLYLCHLRIRELQHICLGILNYFRSVERTLTINTSGLTLVS 559


>gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens]
          Length = 1111

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 13/125 (10%)

Query: 151 KTRGRLYLRPELLAKRPCVDIQEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFS 210
           K  G L    +L AK    ++     +K ++ +      +  + K  F  S  +E     
Sbjct: 569 KVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRL----VHYRYKPEFAASAGIEATAPE 624

Query: 211 TEKLLQRIKEILPQYVS-----AFANTDGGYLFIGLNEDK---EIIGFKAEMSDL-DDLE 261
           T  + Q +KEILP+ V       FAN      F+ +N+++   E +G   E+  L D+LE
Sbjct: 625 TGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKERIFMENVGAVKELCKLTDNLE 684

Query: 262 REIEK 266
             I++
Sbjct: 685 TRIDE 689


>gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens]
          Length = 1151

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 13/125 (10%)

Query: 151 KTRGRLYLRPELLAKRPCVDIQEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFS 210
           K  G L    +L AK    ++     +K ++ +      +  + K  F  S  +E     
Sbjct: 578 KVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRL----VHYRYKPEFAASAGIEATAPE 633

Query: 211 TEKLLQRIKEILPQYVS-----AFANTDGGYLFIGLNEDK---EIIGFKAEMSDL-DDLE 261
           T  + Q +KEILP+ V       FAN      F+ +N+++   E +G   E+  L D+LE
Sbjct: 634 TGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKERIFMENVGAVKELCKLTDNLE 693

Query: 262 REIEK 266
             I++
Sbjct: 694 TRIDE 698


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,874,342
Number of Sequences: 37866
Number of extensions: 918787
Number of successful extensions: 2201
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2131
Number of HSP's gapped (non-prelim): 27
length of query: 578
length of database: 18,247,518
effective HSP length: 108
effective length of query: 470
effective length of database: 14,157,990
effective search space: 6654255300
effective search space used: 6654255300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.