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Search of human proteins with 156766047
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
(1293 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 2590 0.0
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 2583 0.0
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 2583 0.0
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 2564 0.0
gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens] 743 0.0
gi|148746195 trichohyalin [Homo sapiens] 157 6e-38
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 140 8e-33
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 137 5e-32
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 137 9e-32
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 135 3e-31
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 134 4e-31
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 134 6e-31
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 134 6e-31
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 134 7e-31
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 127 5e-29
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 120 8e-27
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 116 1e-25
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 114 5e-25
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 114 5e-25
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 114 5e-25
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 114 5e-25
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 114 5e-25
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 114 5e-25
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 114 5e-25
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 114 5e-25
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 113 1e-24
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 108 3e-23
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 106 2e-22
gi|221139761 zinc finger protein 853 [Homo sapiens] 105 2e-22
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 104 5e-22
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 2590 bits (6713), Expect = 0.0
Identities = 1293/1293 (100%), Positives = 1293/1293 (100%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
Query: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPGWR 240
NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPGWR
Sbjct: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPGWR 240
Query: 241 EHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAF 300
EHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAF
Sbjct: 241 EHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAF 300
Query: 301 LSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEA 360
LSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEA
Sbjct: 301 LSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEA 360
Query: 361 SEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRG 420
SEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRG
Sbjct: 361 SEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRG 420
Query: 421 DEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEE 480
DEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEE
Sbjct: 421 DEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEE 480
Query: 481 GLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQ 540
GLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQ
Sbjct: 481 GLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQ 540
Query: 541 GPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELD 600
GPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELD
Sbjct: 541 GPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELD 600
Query: 601 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 660
QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL
Sbjct: 601 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 660
Query: 661 KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQL 720
KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQL
Sbjct: 661 KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQL 720
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
Query: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840
RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE
Sbjct: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840
Query: 841 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 900
AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL
Sbjct: 841 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 900
Query: 901 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960
RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR
Sbjct: 901 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960
Query: 961 QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020
QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP
Sbjct: 961 QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020
Query: 1021 NRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEV 1080
NRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEV
Sbjct: 1021 NRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEV 1080
Query: 1081 GPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHAL 1140
GPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHAL
Sbjct: 1081 GPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHAL 1140
Query: 1141 NTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQ 1200
NTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQ
Sbjct: 1141 NTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQ 1200
Query: 1201 QQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1260
QQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK
Sbjct: 1201 QQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1260
Query: 1261 QKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1293
QKMVRADPSLLGFSVNASSERLNMGEIETLDDY
Sbjct: 1261 QKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1293
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 2583 bits (6696), Expect = 0.0
Identities = 1293/1299 (99%), Positives = 1293/1299 (99%), Gaps = 6/1299 (0%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
Query: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSP--- 237
NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSP
Sbjct: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP 240
Query: 238 ---GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 294
GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF
Sbjct: 241 RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 300
Query: 295 DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 354
DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD
Sbjct: 301 DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360
Query: 355 RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 414
RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA
Sbjct: 361 RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420
Query: 415 KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 474
KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST
Sbjct: 421 KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480
Query: 475 EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 534
EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD
Sbjct: 481 EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540
Query: 535 PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 594
PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP
Sbjct: 541 PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600
Query: 595 HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 654
HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL
Sbjct: 601 HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 660
Query: 655 QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 714
QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG
Sbjct: 661 QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
Query: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL
Sbjct: 901 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ
Sbjct: 961 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
Query: 1015 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1074
QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD
Sbjct: 1021 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1080
Query: 1075 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1134
DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE
Sbjct: 1081 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1140
Query: 1135 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1194
QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA
Sbjct: 1141 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1200
Query: 1195 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1254
NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS
Sbjct: 1201 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1260
Query: 1255 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1293
GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
Sbjct: 1261 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1299
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 2583 bits (6696), Expect = 0.0
Identities = 1293/1299 (99%), Positives = 1293/1299 (99%), Gaps = 6/1299 (0%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
Query: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSP--- 237
NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSP
Sbjct: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP 240
Query: 238 ---GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 294
GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF
Sbjct: 241 RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 300
Query: 295 DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 354
DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD
Sbjct: 301 DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360
Query: 355 RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 414
RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA
Sbjct: 361 RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420
Query: 415 KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 474
KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST
Sbjct: 421 KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480
Query: 475 EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 534
EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD
Sbjct: 481 EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540
Query: 535 PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 594
PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP
Sbjct: 541 PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600
Query: 595 HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 654
HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL
Sbjct: 601 HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 660
Query: 655 QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 714
QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG
Sbjct: 661 QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
Query: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL
Sbjct: 901 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ
Sbjct: 961 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
Query: 1015 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1074
QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD
Sbjct: 1021 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1080
Query: 1075 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1134
DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE
Sbjct: 1081 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1140
Query: 1135 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1194
QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA
Sbjct: 1141 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1200
Query: 1195 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1254
NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS
Sbjct: 1201 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1260
Query: 1255 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1293
GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
Sbjct: 1261 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1299
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 2564 bits (6646), Expect = 0.0
Identities = 1292/1321 (97%), Positives = 1292/1321 (97%), Gaps = 29/1321 (2%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG-- 178
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180
Query: 179 --------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 218
RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG
Sbjct: 181 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240
Query: 219 GWRLAGSRRDGERWRPHSP------GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 272
GWRLAGSRRDGERWRPHSP GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI
Sbjct: 241 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 300
Query: 273 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 332
DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE
Sbjct: 301 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 360
Query: 333 GSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKD 392
GSHNEEAKEPDKTNKKEGEKTDRVGV ASEETPQTSSSSARPGTPSDHQSQEASQFERKD
Sbjct: 361 GSHNEEAKEPDKTNKKEGEKTDRVGV-ASEETPQTSSSSARPGTPSDHQSQEASQFERKD 419
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP
Sbjct: 420 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 479
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE
Sbjct: 480 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 539
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 572
HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ
Sbjct: 540 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 599
Query: 573 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 632
PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ
Sbjct: 600 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 659
Query: 633 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 692
VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA
Sbjct: 660 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 719
Query: 693 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 752
SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ
Sbjct: 720 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 779
Query: 753 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE
Sbjct: 780 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE
Sbjct: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC
Sbjct: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
Query: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992
QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
Query: 993 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1052
TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA
Sbjct: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1079
Query: 1053 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112
SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE
Sbjct: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
Query: 1113 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1172
EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL
Sbjct: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199
Query: 1173 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1232
GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST
Sbjct: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259
Query: 1233 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1292
LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD
Sbjct: 1260 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1319
Query: 1293 Y 1293
Y
Sbjct: 1320 Y 1320
>gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens]
Length = 1035
Score = 743 bits (1917), Expect = 0.0
Identities = 425/840 (50%), Positives = 535/840 (63%), Gaps = 134/840 (15%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAET LNFGPEWLRALS GGS+ SPP SPA+PKYKLADYRYGREEMLAL++K+NK+P
Sbjct: 1 MAAET--LNFGPEWLRALSGGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPE 58
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
+L DKEF +LQ+EPL PLAL P TEEEQRNFS+SVNS AVLRL G+G G + G RGR
Sbjct: 59 ELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGR 118
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
S+R RGRGRG+ FYQRS +E +G FGR RE+ RSQSW++RG+RRFEK R+D R
Sbjct: 119 GSTRSRGRGRGDSCFYQRSIEEGDGAFGRSP-REIQRSQSWDDRGERRFEKSARRDGARC 177
Query: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRL-AGSRRDGERWR------ 233
FEEGG G + E RS+SENWR REEQ E+E+G WRL AG RRDG+RWR
Sbjct: 178 GFEEGG---AGPRKEHARSDSENWRSLREEQE-EEEEGSWRLGAGPRRDGDRWRSASPDG 233
Query: 234 -PHSPGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGS-----------IDDDRDSLPE 281
P S GWREH ERRR+FEFD R G R G GS ++D+D LPE
Sbjct: 234 GPRSAGWREHGERRRKFEFDLRGDRGGCGEEEGRGGGGSSHLRRCRAPEGFEEDKDGLPE 293
Query: 282 WCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKE 341
WCL+D +EEMGTFD+SGAFL LKK KEPIPEEQE+DF+ ++E EE S+
Sbjct: 294 WCLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQELDFQGLEEEEEPSE----------- 342
Query: 342 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEK 401
G+E EE P+ P P + +S
Sbjct: 343 ---------------GLE--EEGPEAGGKELTPLPPQEEKS------------------- 366
Query: 402 AEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVET 461
S P+ +P+ G PL D PP + +R ++
Sbjct: 367 ---------SSPSPLPTLG---------PLWGTNGDGDETAEKEPPAAEDD---IRGIQL 405
Query: 462 PVVGAPGMGSVSTEP---DDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQ----EHR 514
+PG+GS + P +D+EGLKHL+Q+AEK+VA LQDS+L++E+ + +Q H
Sbjct: 406 ----SPGVGSSAGPPGDLEDDEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHS 461
Query: 515 AKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPL 574
A ++PL H A +KW+YKDPQGEIQGPF QEMAEWFQAGYF+MSLLVKR CDE FQPL
Sbjct: 462 AAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPL 521
Query: 575 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQF--LIQQQYAQ 632
G+++KMWGRVPF+PGP+PPP +G +DQERL +QQEL A Q LQ+QQF L+ +
Sbjct: 522 GEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQQFLQLVSSRQLP 581
Query: 633 VLAQQQKAALS----------SQQQQQLALLLQQFQTLK-MRISDQNIIPSVTRSVSVPD 681
A ++KAAL QQQQQL LQQ Q LK R DQN++P+++RS+SVPD
Sbjct: 582 QCALREKAALGDLTPPPPPPPQQQQQQLTAFLQQLQALKPPRGGDQNLLPTMSRSLSVPD 641
Query: 682 TGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMR 741
+G +W++ +AS + E S+WD+P++++T GP LEQLQ K QERRE E+R
Sbjct: 642 SGRLWDVHTSASSQSGGE-ASLWDIPINSSTQGPILEQLQLQHKF------QERREVELR 694
Query: 742 AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK---QEEALRRQREQEIAL 798
AKREEEERKR+EE RRQQ QQEE+++R+EEEEL RRK Q+E L + +Q+ A+
Sbjct: 695 AKREEEERKRREEKRRQQ------QQEEQKRRQEEEELFRRKHVRQQELLLKLLQQQQAV 748
Score = 244 bits (624), Expect = 3e-64
Identities = 169/442 (38%), Positives = 231/442 (52%), Gaps = 96/442 (21%)
Query: 865 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 924
E +L+H+ +ER+ EL +R++E ++R++ +R QQQQ++Q
Sbjct: 677 EQLQLQHKFQERREVELRAKREEEERKRREE-----KRRQQQQEEQ-------------- 717
Query: 925 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG-- 982
K +E E R + RQQ L+K LQQQQ
Sbjct: 718 --------------------KRRQEEEELFRRKHVRQQELLLKLLQQQQAVPVPPAPSSP 757
Query: 983 ---WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSV 1039
W ++K + K+LLE+Q E RQ+ KQ ++ P RA+ H
Sbjct: 758 PPLWAGLAKQGLSMKTLLELQLEGERQLHKQPPPRE----PARAQAPNH--------RVQ 805
Query: 1040 WGSINTGPPNQWASDLVSSIWSNADTK---NSNMGFWDDAVKEVGP--RNSTNKN-KNNA 1093
G + T P NQW S+ +W D +S +G W+D K G R KN +++
Sbjct: 806 LGGLGTAPLNQWVSE-AGPLWGGPDKSGGGSSGLGLWEDTPKSGGSLVRGLGLKNSRSSP 864
Query: 1094 SLSKSVG-VSNRQ-NKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTF 1151
SLS S +S R KK EEEEKLLKL QG+ + QDGFTQWCEQMLH L+ +LDVP
Sbjct: 865 SLSDSYSHLSGRPIRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATGSLDVPMA 924
Query: 1152 VSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQP 1211
V+ LKEVESPY+VHDYIR+ LGDT EAKEFAKQFLERRAKQKA+QQRQQQQ
Sbjct: 925 VAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQ--------- 975
Query: 1212 PQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLL 1271
W ++ ++L + FQ N S + + K K++ M+ +DPS+L
Sbjct: 976 ------------EAW-LSSASLQTAFQANHS----TKLGPGEGSKAKRRALMLHSDPSIL 1018
Query: 1272 GFSVNASSERLNMGEIETLDDY 1293
G+S++ SS GEIE++DDY
Sbjct: 1019 GYSLHGSS-----GEIESVDDY 1035
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 157 bits (397), Expect = 6e-38
Identities = 97/322 (30%), Positives = 189/322 (58%), Gaps = 39/322 (12%)
Query: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEE---RKRQEELRRQQEEILRRQQEEERKRRE 775
+L +L + + +Q+RRE + R +EEEE RKR+ LR+++E++ + + +R+ +E
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 776 EEELARRKQEEALRRQREQEIA----------LRRQREEEERQQQEEALRRLEERRREEE 825
EEE R+ + + LRR+R++E LRR++EEE R+QQEE RR ++ RRE++
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE--RREQQERREQQ 331
Query: 826 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 885
E R++++L R+QEE + R E+E +RR ++ R EEE + E++ R+E +++R
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 886 QKELMRQRQ-QQQEALRRLQQQQQQQQL---AQMKLPSSSTWGQQSNTTACQSQATLSLA 941
+++L R++Q ++++ LRR QQ +++QQL Q++ +Q + + Q
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ------ 445
Query: 942 EIQKLEEERERQLREEQRRQQRELMKALQQ-QQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
+++ +EER L+ E+ ++ E + QQ ++ Q++++ W L+++
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW-------------LKLE 492
Query: 1001 QEEARQMQKQQQQQQQHQQPNR 1022
+EE R+ Q++++QQ + +Q R
Sbjct: 493 EEERREQQERREQQLRREQEER 514
Score = 151 bits (382), Expect = 3e-36
Identities = 109/361 (30%), Positives = 202/361 (55%), Gaps = 66/361 (18%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI----LRRQQEEERK- 772
+QL++ ++ + + ++ERRE + R RE++E +R+++LRR+QEE LRR+QEEER+
Sbjct: 304 QQLRRKQEEERREQQEERREQQER--REQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 773 ---RREEEELARRKQ---------EEALRRQ----REQEIALRRQREEEERQQQEEALRR 816
RRE+EE R +Q E+ LRR+ REQ++ +Q E++ ++E+ LRR
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 817 LEERRREEEERR--------KQEELLRKQEEEAAKWAREEEEAQRRLEENR--------- 859
++ RRE+EE R ++E+ L++++EE W + EEE +R +E R
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 860 -------LRMEEEAAR---------LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRL 903
L++EEE R LR E+EER+ + L+ Q ++E ++QR + ++ LRR
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 904 QQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ----- 958
Q+++++Q L + + ++ Q + L +++ EE R+++L+ EQ
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQL--LKREEERRQQRLKREQEERLE 599
Query: 959 RRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
+R +RE ++ L+Q+++++Q+ + KS +QEE RQ Q +++QQ++ +
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS---EEQEERRQQQLRREQQERRE 656
Query: 1019 Q 1019
Q
Sbjct: 657 Q 657
Score = 149 bits (375), Expect = 2e-35
Identities = 99/316 (31%), Positives = 187/316 (59%), Gaps = 28/316 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--EERKRRE 775
EQL++LE+ + + QE + + R +RE++ R++QEE RR+Q+E R QQE E+++ R
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 776 EEELARRKQE---EALRRQREQEIA---LRRQREEEERQQQ---EEALRRLEERRREEEE 826
E++L R ++E + LRR++E+E LRR++EEE R+QQ E+ LRR ++ RRE++
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 827 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886
RR+Q +L R+Q+ + R E++ +R E +LR E+E R ++ E++R+E ++R+
Sbjct: 396 RREQ-QLRREQQLRREQQLRREQQLRR---EQQLRREQEEER-HEQKHEQERREQRLKRE 450
Query: 887 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946
+E R +++E R +Q++++QQL + + L E ++
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLK-----------RDQEEERRERWLKLEEEERREQ 499
Query: 947 EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1006
+E RE+QLR EQ ++ + +K Q+++++ QQ+L + + + L ++EE R
Sbjct: 500 QERREQQLRREQEERREQRLKR-QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 1007 MQKQQQQQQQHQQPNR 1022
Q++++Q+ + +Q R
Sbjct: 559 EQERREQRLKREQEER 574
Score = 147 bits (370), Expect = 8e-35
Identities = 254/1166 (21%), Positives = 480/1166 (41%), Gaps = 188/1166 (16%)
Query: 157 RSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDE 216
R + EER +++ E+ R+ + EE + R+ E R E E + + E+
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDW-LKREEETERHEQERRKQQLKRDQEEER 484
Query: 217 DGGW-RLAGSRRDGERWRPHSPGWREHMERR-RRFEFDFRDRDDERGYRRVRSGSGSIDD 274
W +L R ++ R RE ERR +R + R ++ER +R+RS +
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLK---RQEEEERLQQRLRSEQ-QLRR 540
Query: 275 DRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIP-----EEQEMDFRPVDEGEECS 329
+++ E L+ EE+ + LK+ Q+E EE+ R E EE
Sbjct: 541 EQEERREQLLKREEEKR--LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
Query: 330 DSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFE 389
+ E + + +++ K + E EE Q S + + + Q
Sbjct: 599 EQRLKREEVERLEQEERREQRLKRE----EPEEERRQQLLKS------EEQEERRQQQLR 648
Query: 390 RKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPV 449
R+ + + EQ K EEE E L ++ +E + Q L++ + A + +
Sbjct: 649 REQQERREQRLKREEE---EERLEQRLKREHEEERRE--QELAEEEQEQARERI--KSRI 701
Query: 450 PNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASK 509
P L V + P +EG + ++Q EK + +E A +
Sbjct: 702 PKWQWQLESEADA-----RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756
Query: 510 LQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDE 569
Q+ + +A +K + + P Q + + ++ ++
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ--------LRAEERQQREQ 808
Query: 570 SFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQ 629
F P E +++ R+Q ++Q L+ ++ L +++
Sbjct: 809 RFLP------------------------EEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 630 YAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQ 689
AQ L +++ Q++++ +Q + K R W+L+
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQ---EQRRDQKWR----------------------WQLE 879
Query: 690 PTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEE 747
+ T PAL++ + E+ + E+E R E E R ++E+E
Sbjct: 880 EERKRRR------------HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 748 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIA-----LRRQ- 801
+ R+EE +Q+EE L R EE KRR +E + ++++ L+++ EQ + RRQ
Sbjct: 928 RQYREEEQLQQEEEQLLR--EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 802 -----REEEERQQQEEALRR--LEERRREEEER--RKQEELLRKQEEEAAKWAREEEEAQ 852
REEEE QQ+EE L R E+RRR+E ER RK++EL +QEEE + REE E +
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL--QQEEE--QLLREEREKR 1041
Query: 853 RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQL 912
R E R EEE L+ EEE+ +E E +R++EL RQ ++++E QQ+++QL
Sbjct: 1042 RLQERERQYREEE--ELQQEEEQLLGEERETRRRQELERQYRKEEEL------QQEEEQL 1093
Query: 913 AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 972
+ + +Q C+ + L E Q L EERE++ R+E RQ RE + Q++
Sbjct: 1094 LREEPEKRR---RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 973 QQ---------QQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRA 1023
+Q ++Q+ + + + LL +QE+ RQ +++Q ++++ Q +
Sbjct: 1151 EQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210
Query: 1024 RNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPR 1083
+ S + W QW + +++ D K G ++ +++
Sbjct: 1211 KQRYRDEDQRS--DLKW---------QWEPEKENAV---RDNKVYCKGRENEQFRQL-ED 1255
Query: 1084 NSTNKNKNNASLSKSVGVSNRQNKKVE------------EEEKLLKLFQGVNKAQDGFTQ 1131
+ ++ L +G ++++ E EEE+L + Q K +D +Q
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Query: 1132 WCEQMLHALNTANNLDVPTFVSFLKE-------VESPYEVHDYIRAYLGDTSEAKEFAKQ 1184
+Q+L T F +E E P + R + + +E ++
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Query: 1185 FLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNN 1244
FLE + + Q+R+++ L ++QQ + ++ Q Q +D + L + Q +
Sbjct: 1376 FLEEEQRLR-RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL-----SRQERD 1429
Query: 1245 QQSNFEAVQSGKKKKKQKMVRADPSL 1270
++ E Q ++++++K + + L
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQL 1455
Score = 142 bits (358), Expect = 2e-33
Identities = 101/323 (31%), Positives = 185/323 (57%), Gaps = 27/323 (8%)
Query: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK--RR 774
L + QQL + + + EQ+ R + + +EEER Q+ + ++E+ L+R+QEE R +R
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR 460
Query: 775 EEE----ELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRRLEERRREEEE 826
EEE E RRKQ+ L+R +E+E RR+R EEEER++Q+E RR ++ RRE+EE
Sbjct: 461 EEETERHEQERRKQQ--LKRDQEEE---RRERWLKLEEEERREQQE--RREQQLRREQEE 513
Query: 827 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENR---LRMEEEAARLRHEEEERKRKELEV 883
RR+Q +++EE + R E++ +R EE R L+ EEE + E+R ++E E
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Query: 884 QRQKELMRQRQQQQEALRRLQQQQQQQQLAQM---KLPSSSTWGQQSNTTACQSQATLSL 940
+R + L R+ +++Q+ L+R Q+++ +Q+L + +L Q+ + + L
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 941 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
+ ++ EE R++QLR EQ+ ++ + +K ++++++ +Q+L + + L E +
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKR-EEEEERLEQRLK---REHEEERREQELAEEE 689
Query: 1001 QEEARQMQKQQQQQQQHQQPNRA 1023
QE+AR+ K + + Q Q + A
Sbjct: 690 QEQARERIKSRIPKWQWQLESEA 712
Score = 133 bits (334), Expect = 1e-30
Identities = 101/322 (31%), Positives = 181/322 (56%), Gaps = 36/322 (11%)
Query: 724 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELA 780
++ + + EQER AE + E++ER Q + +R+ EE+ R++QE E +R EEE+L
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194
Query: 781 RRK--------QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER----- 827
K EE LRR+ E LRR+ EE++QQ+ E R+ + E+E R
Sbjct: 195 SCKGHETEEFPDEEQLRRRELLE--LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 828 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME-----EEAARLRHEEEERKRKEL 881
RK+EE L+++E + + +EEEE R+LE LR E ++ RLR E++ R+++E
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 882 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941
E + Q+E +R++QQE RR QQ+++++Q Q++ QQ + + L
Sbjct: 313 ERREQQE---ERREQQE--RREQQEERREQ--QLRREQEERREQQLRREQEEERREQQLR 365
Query: 942 EIQKLEEERERQLREEQR-RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
Q+ EE RE+QLR EQ+ R++++L + +QQ +++Q+L + + + +
Sbjct: 366 REQE-EERREQQLRREQQLRREQQLRR---EQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 1001 QEEARQMQKQQQQQQQHQQPNR 1022
+++ R+ Q++++ +Q+H+Q R
Sbjct: 422 EQQLRREQEEERHEQKHEQERR 443
Score = 130 bits (328), Expect = 6e-30
Identities = 124/437 (28%), Positives = 222/437 (50%), Gaps = 62/437 (14%)
Query: 599 LDQERLTRQQELTALYQMQHLQYQQ----FLIQQQYAQVLAQQQKAALSSQQ--QQQLAL 652
L++E+ R+QE ++ Q L+ Q+ FL ++Q +Q+K QQ +Q+
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 653 LLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTT 712
+Q + K R +Q + +S + + L+ + E + D
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE------ 1601
Query: 713 PGPALEQLQQLEKAKAAKLEQERR---EAEMRAKREEEERKRQEELRR--QQEEILRRQQ 767
+QL++ E + + E++R+ + ++ +REE++ RQE R+ ++E LRRQ+
Sbjct: 1602 -----QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1656
Query: 768 EEE-------RKRREEEELARRKQEEALRRQ------REQEIALRRQREEEERQQQEEAL 814
E+ RK REEE+L + +E+ LRRQ RE+E LRRQ E + Q+E+ L
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 815 RRLE-ERRREEEERRKQE---ELLRKQE-------EEAAKWAREEEEAQRR------LEE 857
RR E ER+ EEE+ +QE E LR+QE EE + REE++ +R+ EE
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Query: 858 NRLRMEEEAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916
+LR E E +LR +E +RK R+E ++++++E + R QQ++ R +++Q Q + + +
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE--LMKALQQQQQ 974
L +Q +++ + E + EE+ Q E++RRQ+RE L + ++QQ
Sbjct: 1837 L-------RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Query: 975 QQQQKLSGWGNVSKPSG 991
+++Q+ G + G
Sbjct: 1890 KEEQRHRQVGEIKSQEG 1906
Score = 127 bits (319), Expect = 7e-29
Identities = 97/325 (29%), Positives = 178/325 (54%), Gaps = 40/325 (12%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-----LRRQQEEE 770
AL Q L++ K A+ + +E+ ++ +R+EE+++R E RQ EE +++QE+E
Sbjct: 88 ALGQATGLDEEKRARCDG--KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE 145
Query: 771 RKRREEEELARRKQ--EEALRRQREQEIALRRQ--REEEERQQQEEALRRLEERRREEEE 826
R+ E EE + +++ E+ R++R++E+ +RQ +E EER+ +EE L+ + E EE
Sbjct: 146 RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSC--KGHETEE 203
Query: 827 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE-----EERKRKEL 881
+E+L R++ E + REE++ QRR ++R+ EEE R E EE K +E
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE 263
Query: 882 EVQRQKELMRQRQQ----QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT 937
E QRQ+EL + +Q +++ LRR +Q+++QQQ +++ Q+ Q +
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ-QRLRREQQLRRKQEEERREQQEERR 322
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
++ EE RE+QLR EQ ++ + ++ Q++++++QQ L
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ-----------------LR 365
Query: 998 EIQQEEARQMQKQQQQQQQHQQPNR 1022
Q+EE R+ Q +++QQ + +Q R
Sbjct: 366 REQEEERREQQLRREQQLRREQQLR 390
Score = 126 bits (316), Expect = 2e-28
Identities = 195/955 (20%), Positives = 388/955 (40%), Gaps = 165/955 (17%)
Query: 149 RGGGREMHRSQSWEERGDRRFEKPGRKD------VGRPNFEEGGPTSVGRKHEFIRSESE 202
R GRE + Q ER DR F++ K+ V R E+ R+ E E +
Sbjct: 219 RRKGRE-EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277
Query: 203 NWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDDERGY 262
++ R+E E ++ + RR+ + R RE E RR + + R++ +ER
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE-QQERREQQEERRE 336
Query: 263 RRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 322
+++R + + + + EEE L++ Q+E E+Q + +
Sbjct: 337 QQLRR------EQEERREQQLRREQEEERRE-------QQLRREQEEERREQQLRREQQL 383
Query: 323 DEGEECSDSEGSHNEEAKEPDKTNKKEGE--------KTDRVGVEASEETPQTSSSSARP 374
++ + E+ ++ ++E + + ++ E EE + R
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 375 GTPSDHQSQEASQFERKDEP--------KTEQTEKAEEETRMENSLPAKVPSRGDEMVAD 426
+ +E + +++E + +Q ++ +EE R E L + R ++
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 427 VQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLE 486
QQ L + + L LR +++ + E
Sbjct: 504 EQQ-LRREQEERREQRLKRQEEEERLQQRLR-------------------SEQQLRREQE 543
Query: 487 QQAEKMVAYLQDSALDDERLASKL--QEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN 544
++ E+++ ++ L+ ER +L ++ + + E Q+ ++ + ++
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 545 NQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERL 604
+E+ Q L + +E Q L E Q++L
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQL----------------LKSEEQEERRQQQL 647
Query: 605 TRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRI 664
R+Q+ +++ + ++ L Q+ + ++++ L+ ++Q+Q + +K RI
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR------ERIKSRI 701
Query: 665 SDQNIIPSVTRSVSVPDTGSIWELQPTA--------SQPTVWEGGSVWDLPLDTTTPGPA 716
W+L+ A S+P EG + +
Sbjct: 702 PKWQ-----------------WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 717 LEQLQQLEKAKAAKLEQERR-------EAEMRAKREEEERKRQEELRRQQEEILR---RQ 766
Q Q+ E+A + E+E+R +AE +++R + + LR Q+E LR RQ
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 826
Q E+R EEEE +R+++ RR+RE+E+ + E+ +R+++ + L+ E+ +E++E
Sbjct: 805 QREQRFLPEEEEKEQRRRQ---RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Query: 827 RRKQEELLRKQEEEAAKWAREEEEAQRR-------------LEENRLRMEEEAARLRHEE 873
RR+ +E R Q+ +W EEE +RR +E +L EEE R E
Sbjct: 862 RRRSQEQRRDQK---WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER 918
Query: 874 EERKRKELEVQ-RQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTW------ 923
E+R+R+E E Q R++E ++Q ++Q +E +R +Q++++Q KL
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
Query: 924 ---GQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 980
+Q + + L E Q L EERE++ R+E RQ R+ LQQ+++Q ++
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK-KDELQQEEEQLLREE 1037
Query: 981 SGWGNVSKPSGTTKSLLEIQQEE----------------ARQMQKQQQQQQQHQQ 1019
+ + + E+QQEE RQ +K+++ QQ+ +Q
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ 1092
Score = 124 bits (311), Expect = 6e-28
Identities = 97/370 (26%), Positives = 191/370 (51%), Gaps = 83/370 (22%)
Query: 718 EQLQQLEKAKAAKLEQE---RREAEMRAKREEEERKRQEE------------------LR 756
+QL + E+ + +LE++ R+E E + +E++ +RQE L+
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 757 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE-------------QEIALRRQRE 803
++E+ L RQ+ + + EE +L R+++E+ LR R+ +E LRRQ
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 804 EEERQQQEEALRRLEERRR--EEEERRKQEELLRK-QEEEAAKWAREEEEAQRR------ 854
+ + +++E+ LRR E R+ +EE++ +++EL RK +EEE + E+E+ +R+
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 855 LEENRLRMEEEAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRR----LQQQQQQ 909
LEE +LR E E +LR +E +RK R+E ++++++E + R Q+ + R L+Q++++
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Query: 910 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR--------EEQRRQ 961
QQL + W ++ Q L E Q+L +ER+RQ R E+ RR+
Sbjct: 1810 QQLRPQQRDGKYRWEEE--------QLQLEEQE-QRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 962 QRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPN 1021
++EL + +Q+++Q++++ ++++E R+ QK++Q+ +Q +
Sbjct: 1861 EQELWQEEEQKRRQERER------------------KLREEHIRRQQKEEQRHRQVGEIK 1902
Query: 1022 RARNNTHSNL 1031
H L
Sbjct: 1903 SQEGKGHGRL 1912
Score = 123 bits (308), Expect = 1e-27
Identities = 95/324 (29%), Positives = 177/324 (54%), Gaps = 31/324 (9%)
Query: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR-QQEEILRRQQEEERKRRE 775
LE+ QQL + + K R E ++ +REE++ RQE R+ +EE R+QE +RK RE
Sbjct: 1449 LEEEQQLRQERHRKF---REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 776 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE--ERRREEEERRKQEEL 833
+E + +E R+ E+E L RQ+ + + Q+E+ LRR E ++RR++ +R+ +EE
Sbjct: 1506 QE----LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
Query: 834 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 893
+QE E + +R+E + + RLEE ++R +E+ + +E++ +R+E + Q ++E R+
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 894 QQQQEALRRLQQQQQQQQLAQMK-LPSSSTWGQQSNTTACQSQATLSLAEIQKL------ 946
++ ++ L+ ++QQ +Q K L +Q + E ++L
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
Query: 947 ----EEERERQLREEQ---RRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 999
+ER+R+ REE+ RRQ+RE K LQ++QQ ++Q+L K + E
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERE-RKFLQEEQQLRRQELE-----RKFREEEQLRQET 1735
Query: 1000 QQEEARQMQKQQQQQQQHQ-QPNR 1022
+QE+ R+ ++ ++ ++ Q +P R
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRPER 1759
Score = 121 bits (304), Expect = 4e-27
Identities = 124/479 (25%), Positives = 224/479 (46%), Gaps = 64/479 (13%)
Query: 600 DQERLTRQQELTALYQMQHLQY-QQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQ 658
++E+L R++ Q QY ++ +QQ+ Q+L ++Q+ +++Q Q Q
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 659 TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 718
K R D++ + ++ + + + + D L L+
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
Query: 719 QLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQE---------------ELRRQQEE 761
L L + + EQERR + R + EEE+ +R+E +L R++ E
Sbjct: 1269 HL--LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
Query: 762 ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER- 820
RR+QE +RK REEE+L + ++E+ LRRQ R+ EEE + QE+ + LEE
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERD-----RKFREEELRHQEQGRKFLEEEQ 1381
Query: 821 --RREEEERR--KQEELLRKQEEEAA------KWAREEEEAQRRLEENRLRMEEEAARLR 870
RR+E ER+ K+E+ LR QE E + REEE+ R E +R + EE ++R
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR-KFREEEQQVR 1440
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ------------QQQQLAQM--- 915
+E ERK E E Q ++E R+ +++++ L+ ++QQ ++QQL +
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 916 -KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 974
K Q+ + + L + Q+ + E+QLR ++R QQR + + +++
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 975 QQQQKLSGWGNVSKPSGTTKSLLEIQQ-----------EEARQMQKQQQQQQQHQQPNR 1022
+Q ++ +S+ K LE Q+ E+ +Q+++Q+ QQQ Q+ +R
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
Score = 120 bits (302), Expect = 6e-27
Identities = 102/329 (31%), Positives = 171/329 (51%), Gaps = 36/329 (10%)
Query: 718 EQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEE---LRRQQ------EEILRRQ 766
+QL+ E+ + + +++R RE E + R+E +RK +EE +RRQ+ EE + +
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456
Query: 767 QEEERKRREEEELARRKQEEALRRQR------EQEIALRRQREEEERQQQEEALRRLEER 820
QE RK REEE+L + ++E+ L RQ E+E LRRQ E +R+ +E+ LR E
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ--ERDRKFREQELRSQEPE 1514
Query: 821 RR--EEEERRKQEELLRKQEEEAAKWAREEEEAQRR-------LEENRLRMEEEAARLRH 871
R+ EEE++ +++ RK +E + R+E QRR EE +LR E E +L
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Query: 872 EEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
+E +RK R E + R++E R+ + ++ LRR + QQQ +Q K Q+
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 931 ACQSQ---ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVS 987
Q E Q +ERE+QLR ++ R+ RE + LQ+ ++QQ ++
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER----D 1690
Query: 988 KPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1016
+ + L Q+ E + +Q++QQ ++Q
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Score = 116 bits (291), Expect = 1e-25
Identities = 90/327 (27%), Positives = 184/327 (56%), Gaps = 29/327 (8%)
Query: 718 EQLQQLEKAKAAKLEQE----RREAEMRAKREEEERKRQE--ELRRQQEEILRRQQEEER 771
EQ + ++ + LE+E R++ + + +EE++ +RQE + RRQ + R++E+ R
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564
Query: 772 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE--ERRREEEERRK 829
+ REE++L+R++++ R+ R +E +RRQ +E + + E+ LRR E ++ R+E +R+
Sbjct: 1565 QEREEQQLSRQERD---RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 830 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE------EEERKRKELEV 883
+E+ QE E + R+E + + EE +LR +E +LRH+ EEE+ +E E
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
Query: 884 Q--RQKELMRQRQQQQEALRRLQQQ----QQQQQLAQMKLPSSSTWGQQSNTTACQSQAT 937
Q R++E R+ +++++ LRR +++ Q++QQL + +L +Q Q Q
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
+ LEEE+ R REEQ+ +++E + ++++Q +Q++ + + +S
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER------EEQQLRSQESDR 1795
Query: 998 EIQQEEARQMQKQQQQQQQHQQPNRAR 1024
+ ++EE + ++++QQ + Q+ + R
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYR 1822
Score = 115 bits (287), Expect = 4e-25
Identities = 89/308 (28%), Positives = 170/308 (55%), Gaps = 20/308 (6%)
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEE---RKRQEELRRQQEEILRRQQEEERKRREE 776
L++ + + + EQ+ R R REEE+ +++LRRQ+ + + ++EE++ RR+E
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD-RKFREEEQQLRRQE 1704
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQ--QEEALRRLEERRR--EEEERR--KQ 830
E ++E+ LRRQ + R+ REEE+ +Q ++E LRR E R+ EEE+ R ++
Sbjct: 1705 RERKFLQEEQQLRRQELE----RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 831 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM 890
E+ LR+QE + + REEE+ ++ EE +LR +E + R EE+ R+ +E + R ++
Sbjct: 1761 EQQLRRQERD--RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Query: 891 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 950
+ + ++E L+ +Q+Q+ +Q + + + Q + + + L E QK +ER
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR--REEQELWQEEEQKRRQER 1876
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
ER+LREE R+Q++ + +Q + + Q+ G G + +P T + + +
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPG--THQFASVPVRSSPLYEYI 1934
Query: 1011 QQQQQQHQ 1018
Q+Q+ Q++
Sbjct: 1935 QEQRSQYR 1942
Score = 113 bits (283), Expect = 1e-24
Identities = 103/392 (26%), Positives = 180/392 (45%), Gaps = 87/392 (22%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
E++QQ E+ + ++RR E+ + EEE +QEE + +EE +R+QE ER+ REEE
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 778 ELARRKQEEALR---------------------------------------------RQR 792
EL R+K+++ R RQ
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263
Query: 793 EQEIA------LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 846
+Q++ R RE+E R+ Q+ EE + E EE+++ + RK +EE
Sbjct: 1264 QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE 1323
Query: 847 EEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQ---------KELM 890
E EE +RR EE +L E E LR +E +RK +E E++ Q ++ +
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383
Query: 891 RQRQQQQEALRRLQQ---QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
R+++++++ L+ QQ Q+++QQL Q + QQ + + ++++ E
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 948 EER-----ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
ER E+QLR+E+ R+ RE + LQ++++QQ + + LE +Q+
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR----------QERDRKFLEEEQQ 1493
Query: 1003 EARQM--QKQQQQQQQHQQPNRARNNTHSNLH 1032
RQ +K ++Q+ + Q+P R LH
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
Score = 110 bits (275), Expect = 9e-24
Identities = 89/334 (26%), Positives = 174/334 (52%), Gaps = 45/334 (13%)
Query: 732 EQERR--EAEMRAKREEEERK---RQEELRRQQEEILRRQQEEERKRREEEELAR----- 781
EQ R+ E E R +R+E ERK +++LR Q+ E RQ + + R EE++L+R
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 782 --RKQEEALRRQR------EQEIALR--------------RQREEEERQQQEEALRRLEE 819
R++E+ +RRQ E+E LR ++REE++ +QE + LEE
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 820 R---RREEEERRKQEELLRKQEEEAAKWAREEEEAQRR-------LEENRLRMEEEAARL 869
RR+E +R+ +E+ LR QE E K+ EE++ R+ EE +LR +E +
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPE-RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 870 RHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK-LPSSSTWGQQSN 928
R + + + R+E ++++++E + +Q+++ RL++Q+ ++Q + K + +Q
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 929 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSK 988
+ + E ++L +ERE Q Q R ++ L + Q ++Q+++Q+L K
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR-HDRDRK 1668
Query: 989 PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1022
+ L E ++++ R+ ++ ++ +++ QQ R
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Score = 39.7 bits (91), Expect = 0.019
Identities = 52/280 (18%), Positives = 108/280 (38%), Gaps = 42/280 (15%)
Query: 159 QSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFI------RSESENWRIFREEQ- 211
Q W+ER +RR E+ + EE R+ E + R E + R R+++
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 212 NGEDEDGGWRLAGS--RRDGERWRPHSPGWREHMERRRRFEFDFRDRDDERGYRRVRSGS 269
E+E+ WR + R++ E+ + P +R+R + ++E R++
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEP------QRQRELQ------EEEEQLRKL---- 281
Query: 270 GSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECS 329
+R L E+ +++ + +++ + +QE + R E
Sbjct: 282 -----ERQELRRERQEEEQQQQ------------RLRREQQLRRKQEEERREQQEERREQ 324
Query: 330 DSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFE 389
EE +E ++E + ++ E EE + + + Q + Q
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 390 RKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQ 429
R+ + + EQ + E++ R E L + R ++ + QQ
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Score = 38.1 bits (87), Expect = 0.055
Identities = 49/270 (18%), Positives = 107/270 (39%), Gaps = 22/270 (8%)
Query: 138 RSFDEVEGVFGRGGGREMHRSQSWEERGDRRF--EKPGRKDVGRPNFEEGGPTSVGRKHE 195
R F E E + +++HR + DR+F E+P + R R+ E
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQER-----DRKFLEEEPQLRRQEREQQLRHDRDRKFREEE 1673
Query: 196 FIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRD 255
+ E E ++ R+E++ + + +L R+ + + R+ +ER+ R E R
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Query: 256 RDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQ 315
++ RR ++++ + E E+++ + F +++++ E +
Sbjct: 1734 ETEQEQLRRQERYRKILEEE-----QLRPEREEQQLRRQERDRKFREEEQLRQ----ERE 1784
Query: 316 EMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPG 375
E R + + + E E ++ + +++G+ EE Q R
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK------YRWEEEQLQLEEQEQRLR 1838
Query: 376 TPSDHQSQEASQFERKDEPKTEQTEKAEEE 405
D Q + QF +++ + E+ E +EE
Sbjct: 1839 QERDRQYRAEEQFATQEKSRREEQELWQEE 1868
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 140 bits (353), Expect = 8e-33
Identities = 132/573 (23%), Positives = 269/573 (46%), Gaps = 60/573 (10%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----EERK 772
EQ+Q+ E+ K + E++ RE E + R+EE QE+ R+QE+ +R Q+E +ER
Sbjct: 348 EQMQEQEE-KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406
Query: 773 RREEEELARRK----QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE-R 827
R +EE + ++ Q E +R +++ + ++ R++EE+ Q+EE +R E++ REEEE
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466
Query: 828 RKQEELLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886
R+QEE ++KQEE W +EE+E Q+RL E + ++ E+ +++ +EE+ +E +++ Q
Sbjct: 467 REQEEKMQKQEEN--MWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIWEQEEKIRDQ 523
Query: 887 KELMRQRQQ--QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ---SNTTACQSQATLSLA 941
+E+ Q ++ +QE +R Q+ Q +Q +M+ W Q+ T Q + T
Sbjct: 524 EEMWGQEKKMWRQEKMRE-QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE 582
Query: 942 EIQKLEE---ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 996
E + EE ERE+++REE+ R+Q E M+ +++ Q+Q++K+ W K + +
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM--WEQEEKMQEQEEKM 640
Query: 997 LEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLV 1056
E QEE Q+++ +QQ + + H + + +
Sbjct: 641 WE--QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ---------------EQEKMQEQE 683
Query: 1057 SSIWS----NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112
IW T+ WD +E + + + + + ++ K E+E
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWD---QEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 1113 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1172
EK+ + + + + ++ + E+M + ++E E +E + +R
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR--- 797
Query: 1173 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1232
+E + E + + + + R Q++ Q+++ Q + Q++ +WG
Sbjct: 798 -----DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 1233 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVR 1265
+ + +Q Q K +++++ +R
Sbjct: 853 EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 132 bits (333), Expect = 2e-30
Identities = 106/472 (22%), Positives = 231/472 (48%), Gaps = 53/472 (11%)
Query: 601 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 660
+E+ R +E +++ ++ +Q+Q + Q++K + +++ + ++ +T+
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466
Query: 661 -----KMRISDQNIIPSVTRSVS---VPDTGS-IWELQPTASQPT-VWEGGS-------V 703
KM+ ++N+ + +P+ +WE + Q +WE +
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526
Query: 704 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQ 759
W EQ Q+ + + +QE++ E M K +E+E+K ++ + +
Sbjct: 527 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586
Query: 760 EEILRRQQEEERKRREEEELARRKQEEALRRQRE--QEIALRRQREEEERQQQEEALRRL 817
EE R +E E+K REEEE+ R +QEE ++ Q E QE + +EE+ Q+QEE +
Sbjct: 587 EE--ERMREREKKMREEEEMMR-EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 818 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM-EEEAARLRHEEEER 876
EE+ E+EE+ +++ L +Q+E+ W E+ + Q +++E ++ E+E + +E+E+
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKL--WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 877 KRKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 933
K + E R++E MR+R++ ++E + R Q+++ Q+Q +M+ W Q+ +
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 934 S---------QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG-- 982
+ L E +K++E+ + +EE+ R Q E M+ +++ + Q++K+ G
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 983 ----------WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1024
WG K G + + +++ +MQ Q+++ ++ ++ R +
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Score = 127 bits (319), Expect = 7e-29
Identities = 93/314 (29%), Positives = 174/314 (55%), Gaps = 26/314 (8%)
Query: 732 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREEEELARRKQEEAL 788
E+E RE E + +++EE+ RQEE R+QE +R Q+E+ + KR E+E R+QE+ L
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 789 RRQ---REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER-RKQEELLRKQEE 839
R Q REQE ++ Q E EE+ ++QEE + R EER E+E++ R+QE+ +R QEE
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 840 ---EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 896
E + RE+EE R E+ ++E+ + +E+E+K ++ E + Q+E +R ++
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE---ERIRE 454
Query: 897 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ--SQATLSLAEIQKLEEERERQL 954
+E R +++ ++Q +M+ + W Q+ Q + L E +K++E+ E+
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 955 REEQRRQQRELM----KALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
+E++ + +E M K + +Q++ ++Q+ W K + + + QEE + + Q
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD--QEERMEKKTQ 572
Query: 1011 QQQQQQHQQPNRAR 1024
+Q+++ Q + R
Sbjct: 573 EQEKKTWDQEEKMR 586
Score = 127 bits (319), Expect = 7e-29
Identities = 107/455 (23%), Positives = 226/455 (49%), Gaps = 45/455 (9%)
Query: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
+QE R+QE Q + L+ Q+ +++Q ++ Q++ Q Q+Q + +Q +
Sbjct: 304 EQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE- 362
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS-VWDLPLDTTTPGPALE 718
KMR ++ + R E + + +WE + + E
Sbjct: 363 -KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE-- 776
Q++++ + K + EQE++ + K +EEER R+ E + ++EE R+QEE+ +++EE
Sbjct: 422 QVEKMREEKKMQ-EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 777 -EELARRKQEEALRRQREQEIALRRQREEEER-QQQEEALR-------------RLEERR 821
E+ + Q++ L Q+E+ + +E+EE+ +QEE +R R E+ R
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 822 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL------------RMEEEAARL 869
+E++ +QEE +R QE++ W +EE ++ E+ + RM E ++
Sbjct: 541 EQEDQMWEQEEKMRDQEQK--MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598
Query: 870 RHEEEERKRKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 926
R EEE + +E ++Q Q+E M+++++ +QE + Q+++ +Q +M W QQ
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 658
Query: 927 SNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ--QQQKLSGWG 984
+ L E +K++E+ + Q +EE+ +Q ++ K Q+Q+++ Q+K+
Sbjct: 659 R-----LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 985 NVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019
++ + + E+ +E+ +MQ+Q+++ Q+ ++
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Score = 120 bits (301), Expect = 8e-27
Identities = 108/453 (23%), Positives = 216/453 (47%), Gaps = 89/453 (19%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E Q+RL Q+E L++ + +Q Q+ I +Q ++ Q++ + +Q + Q+
Sbjct: 487 EWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Query: 658 QTL----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 713
Q KMR +Q + W+ + + T + WD
Sbjct: 545 QMWEQEEKMRDQEQKM----------------WDQEERMEKKTQEQEKKTWD-------- 580
Query: 714 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQ----QEE 769
++ + E+ + + E++ RE E + +EE+ + QEE ++QEE + Q QE+
Sbjct: 581 ----QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
Query: 770 ERKRREEEELARRKQEEALRRQR--EQEIAL---RRQREEEERQQQEEAL---RRLEERR 821
E K E+EE ++E+ +QR EQ+ L + +E+E+ Q+QEE + ++E++
Sbjct: 637 EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 822 REEE------ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 875
+E+E E+ ++EE +R++E K REEEE R EE +M+E+ +++ +EEE
Sbjct: 697 QEQEKKTWDQEKMREEESMRERE----KKMREEEEMMREQEE---KMQEQEEKMQEQEEE 749
Query: 876 RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQ 935
+E ++ Q+E M ++Q+ E +L + ++ Q+ W Q+
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-------QEKIWEQE--------- 793
Query: 936 ATLSLAEIQKLEEERERQL-REEQRRQQRELMKALQQQQQQQQQKLSG-----WGNVSKP 989
+K+ ++ E+ +EE+ R Q E M+ +++ Q++K+ G WG K
Sbjct: 794 --------EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKM 845
Query: 990 SGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1022
G + + E Q + +M++Q+++ + ++ R
Sbjct: 846 WGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMR 878
Score = 117 bits (292), Expect = 9e-26
Identities = 125/567 (22%), Positives = 261/567 (46%), Gaps = 94/567 (16%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREE--------EERKRQEELRRQQEEILRRQQEE 769
E ++L A++ K E + E++ K E + QEE+ RQ+EE+ +E+
Sbjct: 229 ELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL----REQ 284
Query: 770 ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK 829
E+K R++EE R++E R REQE +R Q EE+ +QE+ LR E+ RE+E+ +
Sbjct: 285 EKKIRKQEEKMWRQEE----RLREQEGKMREQ--EEKMWRQEKRLREQEKELREQEKELR 338
Query: 830 QEELLRKQEE-----EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
+++ LR+QEE E W E+EE R EE R EE RL +E++ + +E +++
Sbjct: 339 EQKELREQEEQMQEQEEKMW--EQEEKMREQEEKMWRQEE---RLWEQEKQMREQEQKMR 393
Query: 885 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQ---QSNTTACQSQATLSLA 941
Q+E M +Q E LR +++ ++Q+ W Q Q Q +
Sbjct: 394 DQEERM---WEQDERLREKEERMREQE---------KMWEQVEKMREEKKMQEQEKKTRD 441
Query: 942 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001
+ +K++EE + RE++ R++ E M+ +Q+++ Q+Q+ + W K + L Q+
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKE--WQQQRLPEQK 497
Query: 1002 EEARQMQKQQQQQQQ-HQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIW 1060
E+ + +K Q+Q+++ +Q + R+ +WG + + +W
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQ----------EEMWGQEKKMWRQEKMREQEDQMW 547
Query: 1061 SNAD-TKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLF 1119
+ ++ WD +E + + + K + + R+ +++ E EK ++
Sbjct: 548 EQEEKMRDQEQKMWDQ--EERMEKKTQEQEKKTWDQEEKM----REEERMREREKKMREE 601
Query: 1120 QGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAK 1179
+ + + Q+ Q E+ + ++ E +E + ++ E K
Sbjct: 602 EEMMREQEEKMQEQEEKMQ-----------------EQEEKMWEQEEKMQ-----EQEEK 639
Query: 1180 EFAKQFLERRAKQKANQQRQQQQLPQQQQQ----QPPQQPPQQPQQQDSVWGMNHSTLHS 1235
+ + E + ++ + +QQ+LP+Q+++ + Q+ + +Q++ +W +
Sbjct: 640 MWEQ---EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 1236 VFQTNQSNNQQSNFEAVQSGKKKKKQK 1262
Q ++ +Q+ E +++KK +
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMR 723
Score = 99.0 bits (245), Expect = 3e-20
Identities = 100/537 (18%), Positives = 233/537 (43%), Gaps = 45/537 (8%)
Query: 744 REEEERKRQEELRRQQE----EILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR 799
R ++ + EEL ++++ E+ R E +++ EL +++ L + EI L
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL---QEKLPLAESEKSEIQLN 247
Query: 800 RQREEEERQQQEEALRRLEERRREEEERRKQEEL------LRKQEEEAAKWAREE--EEA 851
+ + + ++ + L +++ +EE R++EEL +RKQEE+ W +EE E
Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK--MWRQEERLREQ 305
Query: 852 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 911
+ ++ E +M + RLR +E+E + +E E++ QKEL Q +Q QE Q+++ +Q
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE-----QEEKMWEQ 360
Query: 912 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 971
+M+ W Q+ + Q + QK+ ++ ER +++R +++E Q+
Sbjct: 361 EEKMREQEEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQE 417
Query: 972 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +Q +K+ + + T+ E QEE R +++++ +++ +
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ- 476
Query: 1032 HTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKN 1091
++W Q + +W + W+ K + K
Sbjct: 477 ----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK- 531
Query: 1092 NASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTF 1151
+ + + ++++ E+EEK+ Q + ++ + ++ T + +
Sbjct: 532 --KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE--QEKKTWDQEEKMRE 587
Query: 1152 VSFLKEVESPY-EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQ---- 1206
++E E E + +R E +E ++ E+ +Q+ Q Q++++ +Q
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 1207 -QQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQK 1262
+Q++ + + P+Q++ +W H + Q ++ +E + KK ++Q+
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLW--EHEKMQE--QEKMQEQEEKIWEQEKMEKKTQEQE 700
Score = 98.6 bits (244), Expect = 3e-20
Identities = 138/692 (19%), Positives = 284/692 (41%), Gaps = 110/692 (15%)
Query: 239 WREHMERRRRFEFDFRDRDDE--RGYRRVRSGSGSIDDDRDSL--PEWCLEDAEEEMGTF 294
WR+ E R + E R ++++ R R+R G + + + + E L + E+E+
Sbjct: 275 WRQEEELREQ-EKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333
Query: 295 DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 354
+ + Q+E + E++E + ++ E + E E +K +++ +K
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 355 RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 414
E+ D + +E + R+ E EQ EK EE +M+
Sbjct: 394 DQEERMWEQ---------------DERLREKEERMREQEKMWEQVEKMREEKKMQEQ--- 435
Query: 415 KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 474
++ D ++ + + +R E +
Sbjct: 436 ------EKKTRDQEEKMQE-------------------EERIREREKKM----------- 459
Query: 475 EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 534
++EE ++ E++ +K + + + E +L E + K M E +K + ++
Sbjct: 460 -REEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Query: 535 PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 594
+ Q QE W Q M + ++ + KMW +
Sbjct: 518 EKIRDQEEMWGQEKKMWRQE---KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 595 HMGELDQE-------------RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAA 641
DQE + R++E Q + +Q Q+ +Q+Q ++ Q++K
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM- 633
Query: 642 LSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGG 701
+Q++++ ++ + ++ +Q +P +WE + Q + E
Sbjct: 634 --QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK--------LWEHEKMQEQEKMQEQE 683
Query: 702 S-VWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE 760
+W+ EQ ++ + + E+ RE E + + EEE + QEE ++QE
Sbjct: 684 EKIWE---QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 761 EILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 816
E ++ Q+EE E K E+EE + +++ L Q+E+ + +E+E+ +QEE +R
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEE--KMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRD 798
Query: 817 LEERRR-EEEERRKQEELLRKQEE-----EAAKWARE------EEEAQRRLEENRLRMEE 864
EE+ R +EE+ R QEE +R QEE E W +E EE+ + E+ +M+
Sbjct: 799 QEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQG 858
Query: 865 EAARLRHEEEERKRKELEVQRQKELMRQRQQQ 896
+ ++R +EE+ + +E +++ Q+E MR ++++
Sbjct: 859 QEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 66.2 bits (160), Expect = 2e-10
Identities = 127/634 (20%), Positives = 241/634 (38%), Gaps = 115/634 (18%)
Query: 208 REEQNGEDEDGGWRLAGSRRDGER--WRPHSPGWREHMERRRRFEFDFRDRDDERGYRRV 265
+EEQ E E+ W R+ E WR W + + R + E RD++ ER + +
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ-EQKMRDQE-ERMWEQ- 402
Query: 266 RSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEG 325
D+R L + EE M + + ++K+++E +EQE R +E
Sbjct: 403 --------DER-------LREKEERMR--EQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 326 EECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA 385
+ + ++ +E ++T +++ EK + E+ + P QE
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Query: 386 SQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLIL 445
Q ++E EQ EK ++ M K R ++M Q Q
Sbjct: 506 MQ--EQEEKIWEQEEKIRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQ------------ 549
Query: 446 PPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDER 505
+R E + D EE ++ Q+ EK ++ ++ER
Sbjct: 550 -------EEKMRDQEQKMW------------DQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 506 LASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKR 565
+ + ++ R + + E MQ E + QE W Q M ++
Sbjct: 591 MREREKKMREEEEMMREQEEKMQ---------EQEEKMQEQEEKMWEQEE--KMQEQEEK 639
Query: 566 ACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFL 625
++ + KMW +Q+RL Q+E L++ + +Q Q+ +
Sbjct: 640 MWEQEEKMWEQEEKMW------------------EQQRLPEQKE--KLWEHEKMQEQEKM 679
Query: 626 IQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT--------LKMRISDQNIIPSVTRSV 677
+Q+ + + +Q+K +Q+Q++ ++ + KMR ++ + +
Sbjct: 680 QEQE--EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737
Query: 678 SVPDTGSIWELQPTASQPTVWEGGS-VWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERR 736
+ E + + +WE +W+ E + E+ K + E++ R
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797
Query: 737 EAEMRAKREEEERKRQEELRRQQEEILRRQQE-----------EERKRREEEELARRKQE 785
+ E + + +EE+ + QEE R QEE + Q+E +E K +EE K +
Sbjct: 798 DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQ 857
Query: 786 EALRRQREQEIALRRQRE-----EEERQQQEEAL 814
+ REQE +R Q E EE+ + QEE +
Sbjct: 858 GQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 40.0 bits (92), Expect = 0.014
Identities = 47/241 (19%), Positives = 100/241 (41%), Gaps = 10/241 (4%)
Query: 190 VGRKHEFIRSESENW----RIFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPGWREHM 243
+ + E IR + E W +++R+E+ E ED W RD E+ W ++
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Query: 244 ERRRR-FEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLS 302
E+ ++ ++ + + R++ER R R +++ E +++ EE+M +
Sbjct: 573 EQEKKTWDQEEKMREEER--MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 303 LKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASE 362
K ++E EQE +E E+ E +K ++E + + E
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 363 ETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDE 422
+ + + + + +E S ER+ + + E+ E+E +M+ K+ + +E
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ-EEKMQEQEEE 749
Query: 423 M 423
M
Sbjct: 750 M 750
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 137 bits (346), Expect = 5e-32
Identities = 113/435 (25%), Positives = 222/435 (51%), Gaps = 66/435 (15%)
Query: 603 RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 662
RL +QQE Q + +Q + IQ+Q ++ Q++K ++ ++ ++ + + KM
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 412
Query: 663 RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGSVWDLPLDTTTPGPALEQL 720
R ++ +WE + + +WE E++
Sbjct: 413 RRQEE----------------MMWEKEEKMRRQEEMMWEKE----------------EKI 440
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
++LE+ K+ ++ + E KR+EEE+ R++E R++QE + RQ EE+ R +EE++
Sbjct: 441 RELEE----KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKI- 493
Query: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840
R+QEE + RQ E+ + REEE+RQ+QEE R+ EE+ RE+EE +Q+E + +QEE+
Sbjct: 494 -REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKIHEQEEK 551
Query: 841 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 900
R++EE R EE +M ++ ++R +EE+ R+E +++ Q+E +R +Q+E +
Sbjct: 552 ----IRKQEEKMWRQEE---KMHDQEEKIREQEEKVWRQEEKIREQEEKIR---EQEEKI 601
Query: 901 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960
R ++ Q+Q+ G+Q Q + E + +EE+ R+ +E++ R
Sbjct: 602 REQEEMTQEQE---------EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE-QEKKIR 651
Query: 961 QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020
+Q E ++ ++ Q+Q++K+ W K + + E +++ RQ +K +Q+ + +Q
Sbjct: 652 EQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709
Query: 1021 NRARNNTHSNLHTSI 1035
+L +I
Sbjct: 710 EEKMQEHQEHLEAAI 724
Score = 108 bits (271), Expect = 3e-23
Identities = 85/323 (26%), Positives = 171/323 (52%), Gaps = 47/323 (14%)
Query: 601 QERLTRQQELT-----ALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQ 655
+E++ RQ+E+ + +++ ++Q I++Q + +++K ++Q+Q A + +
Sbjct: 423 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 656 QFQTLKMRISDQNIIPSVTR----SVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTT 711
Q + K+R ++ I + + + I E + Q +W
Sbjct: 482 QEE--KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR------------ 527
Query: 712 TPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--- 768
++ + E+ + + +++ E E + +++EE+ RQEE QEE +R Q+E
Sbjct: 528 ------QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Query: 769 --EERKRREEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRL 817
EE+ R +EE++ R+QEE +R Q +EQE + Q E EE+ Q+QEE +RR
Sbjct: 582 RQEEKIREQEEKI--REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 818 EERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 876
EE+ RE+E++ R+QEE +R+QEE + + E + ++ E +M+E+ ++R +EE+
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Query: 877 KRKELEVQRQKELMRQRQQQQEA 899
+E+ +++Q+E M++ Q+ EA
Sbjct: 700 WEQEVRLRQQEEKMQEHQEHLEA 722
Score = 98.2 bits (243), Expect = 4e-20
Identities = 88/345 (25%), Positives = 174/345 (50%), Gaps = 53/345 (15%)
Query: 705 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 764
+L +T T E+ +L++ K +E E+ E ++ K + + +R + L QQ+
Sbjct: 269 ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 323
Query: 765 RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 823
Q E + +E + ++ + Q + E E+ R Q++EE+ +QEE ++ EE+ +E
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379
Query: 824 EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 865
+EE+ R+QEE +R+QEE E W +EE EE RR EE EE+
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439
Query: 866 AARLRHE--EEERKRKELEVQRQKELMR--QRQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
L + E+E+ R++ E ++++E +R +++Q+QEA Q+++ ++Q +++
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 922 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQ----------RELMKALQQ 971
W Q+ + E +K+ EE +RQ +EE RQ+ R+ K +Q
Sbjct: 500 MWRQEE-----------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548
Query: 972 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1016
+++ ++Q+ W K + + E +++ RQ +K ++Q+++
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK 593
Score = 75.1 bits (183), Expect = 4e-13
Identities = 58/297 (19%), Positives = 139/297 (46%), Gaps = 23/297 (7%)
Query: 730 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 789
+L +ER + R + +E + +E L+ + E+ + + + +RK E A
Sbjct: 258 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 317
Query: 790 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR-KQEEEAAKWAREE 848
+Q++ +E Q L+ E +Q+E +QEE+ +W +
Sbjct: 318 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377
Query: 849 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ 908
+E + ++ E ++ E+ ++R +EE KE +++RQ+E+M +++E +RR ++
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM---WEKEEKMRRQEEMMW 434
Query: 909 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQR-RQQRELMK 967
+++ +L ++ + Q + E +K +E+ + R+E++ R+Q E ++
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 968 ALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1024
+++ +Q++K+ +QE+ R+ +K+Q+Q++ +Q + R
Sbjct: 495 EQEEKMWRQEEKIH------------------EQEKIREEEKRQEQEEMWRQEEKIR 533
Score = 59.3 bits (142), Expect = 2e-08
Identities = 87/500 (17%), Positives = 203/500 (40%), Gaps = 86/500 (17%)
Query: 775 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 808
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 809 --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 856
+ E+AL + ++++ EE K+ + L + E +E +L+
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 857 ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916
E +E E + ++ +E KRK ++R K L+ Q+Q Q EA ++ Q Q +
Sbjct: 289 EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 345
Query: 917 LPSSSTW---GQQSNTTACQSQATLSLAE--IQKLEE---ERERQLREEQRRQQRELMKA 968
+ + W QQ + + + E IQ+ EE E+E ++RE++ + +R+
Sbjct: 346 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405
Query: 969 LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ------QEEARQMQKQQQQQQQHQQPNR 1022
+++++ ++Q+ W K + + E + +E+ + +K ++Q+++ Q+ +
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 465
Query: 1023 ARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGP 1082
R + +W + + + M ++ + E
Sbjct: 466 IREQEKRQEQEA---KMWRQ----------EEKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Query: 1083 RNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNT 1142
K + + RQ +K+ E+E++ + + +++ ++ + E+M
Sbjct: 513 IREEEKRQEQEEMW-------RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Query: 1143 ANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1202
++ + ++ E + + IR E +E ++ E+ +Q+ Q Q+++
Sbjct: 566 MHDQE----EKIREQEEKVWRQEEKIR-------EQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 1203 LPQQQQQQPPQQPPQQPQQQ 1222
+ +Q+++ Q+ Q Q++
Sbjct: 615 MGEQEEKMCEQEEKMQEQEE 634
Score = 47.8 bits (112), Expect = 7e-05
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 61/215 (28%)
Query: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
DQE R+QE Q + ++ Q+ I++Q ++ Q++ ++ +Q++++ ++
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE---MTQEQEEKMGEQEEKMCE 624
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
+ ++ +Q E+
Sbjct: 625 QEEKMQEQE-------------------------------------------------EK 635
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779
+++ E+ K + E++ RE E + + +EE + QEE +QEE + E+E K +E+EE
Sbjct: 636 MRRQEE-KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE---KMCEQEEKMQEQEEK 691
Query: 780 ARRKQEEALRRQREQEIALRRQREE-EERQQQEEA 813
RR++E + EQE+ LR+Q E+ +E Q+ EA
Sbjct: 692 MRRQEE----KMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/410 (17%), Positives = 162/410 (39%), Gaps = 49/410 (11%)
Query: 863 EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 922
+E+ A +H+E R+ E +V + L Q+ + Q AL Q +Q + L S
Sbjct: 170 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 228
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 975
S A + + LS QK + +R +L +E+ EL + L+++ +
Sbjct: 229 --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 286
Query: 976 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
Q+KL + L+ + E A+ + QQQ Q + + + + L +
Sbjct: 287 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 346
Query: 1036 G-NSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1094
N +W +N + +W + W++ ++E + + K
Sbjct: 347 EENELWNRLNQQQEEK--------MWRQEEKIQE----WEEKIQEQEEKIREQEEKIREQ 394
Query: 1095 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1154
K + ++ E+EEK+ + + + + ++ + E M
Sbjct: 395 EEK---MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK------------ 439
Query: 1155 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1214
++E+E + IR E ++ +Q E+R +Q+A RQ++++ +Q++
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEE------ 491
Query: 1215 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
+ +Q++ +W +H + + +Q E + +K ++Q+ +
Sbjct: 492 --KIREQEEKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Score = 36.2 bits (82), Expect = 0.21
Identities = 50/264 (18%), Positives = 105/264 (39%), Gaps = 33/264 (12%)
Query: 154 EMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNG 213
+MH + E+ ++R E+ ++ + +E + R+ E IR + E R
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKIR-------- 494
Query: 214 EDEDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDDE-RGYRRVRSGSGSI 272
E E+ WR + E+ R R+ E R E R++++ R ++ I
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Query: 273 DDDRDSL--PEWCLEDAEEEMGTFDSSGAFLSLKKV---------QKEPIPEEQEMDFRP 321
+ + E + D EE++ + + +K+ Q+E I E++EM
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEK-VWRQEEKIREQEEKIREQEEKIREQEEMT--- 608
Query: 322 VDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQ 381
+E + G E+ E ++ +++ EK R + E+ + + +
Sbjct: 609 ----QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Query: 382 SQEASQFERKDEPKTEQTEKAEEE 405
++ + ++E EQ EK +E+
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQ 688
Score = 34.3 bits (77), Expect = 0.79
Identities = 45/206 (21%), Positives = 86/206 (41%), Gaps = 19/206 (9%)
Query: 162 EERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIF-----REEQNGEDE 216
EE+ R+ EK ++ R + + R+ E IR + E WR +EE+ + E
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 217 DGGWRLAGSRRDGER---------WRPHSPGWREHMERRRRFEFDFRDRDDERGYRRVRS 267
+ WR D E WR RE E+ R E R++++ + +
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEK-IREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 268 GSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-KVQKEPIPEEQEMDFRPVDEGE 326
G +++ E +++ EE+M + K + Q+E I E++EM ++
Sbjct: 616 GE---QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Query: 327 ECSDSEGSHNEEAKEPDKTNKKEGEK 352
E + E+ +E ++ +++ EK
Sbjct: 673 EQEEKMCEQEEKMQEQEEKMRRQEEK 698
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 137 bits (344), Expect = 9e-32
Identities = 90/318 (28%), Positives = 183/318 (57%), Gaps = 22/318 (6%)
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE---EE 777
QQ +A+A L +E + + + + EE + L +QQEE + RQ+E+ ++R E E+
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 778 ELARRKQEEALRRQREQ--EIALRRQREEEERQQQEEALRRLEERR------REEEERRK 829
E R+QEE +RRQ E E + +R+EE ++EE +R LEE+ RE+EE+R+
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 830 QEELLR----KQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 883
+EE +R +QE+EA W +EE+ E + ++ E M+E+ ++ +EE+ +E E+
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 884 QRQKELMRQRQQQ-QEALRRLQQQQQQ-QQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941
Q Q+E MR+++++ +E +++++Q+++ ++ +M G+Q C+ +A +
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG-KMCEQEAKMQEQ 486
Query: 942 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001
E + +E + + +E++ R+Q E ++ ++ Q+Q++K+ W K + + E ++
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEE 544
Query: 1002 EEARQMQKQQQQQQQHQQ 1019
+ RQ +K ++Q+ + +Q
Sbjct: 545 KMRRQEEKMREQEVRLRQ 562
Score = 125 bits (315), Expect = 2e-28
Identities = 71/276 (25%), Positives = 162/276 (58%), Gaps = 15/276 (5%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE----EERKR 773
E+ ++ K + E++ +E E + + +EE+ +RQEE+ ++EE +RRQ+E +E K
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 832
RE EE + ++E +R Q E+ + RE+E+RQ+QE + R EE+ RE+EE+ R+QEE
Sbjct: 347 RELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
++++QEE+ + + E + ++E +M + ++R +E++ + +E +++ Q+E+M++
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Query: 893 RQQQQ--------EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 944
++++ E ++Q+Q+++ + + K+ ++ + + + E +
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 945 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 980
E+E + +EE+ ++Q E M+ +++ ++Q+ +L
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560
Score = 121 bits (304), Expect = 4e-27
Identities = 83/271 (30%), Positives = 161/271 (59%), Gaps = 47/271 (17%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
E++ ++ K +LE++ E E K E+E KRQEE + +++E +RQ++E + R+EE
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQE---KIREQEEKRQEEEKIREQE--KRQEQEAKMWRQEE 390
Query: 778 ELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER- 827
++ R+QEE +R Q +EQE + Q E EEE Q+QEE +RR EE+ RE+E++
Sbjct: 391 KI--REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 828 RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 887
R+QEE +R+QEE +E + ++ E +M E+ A+++ +EE+ +R+E +++ Q+
Sbjct: 449 REQEEKIREQEEMM-------QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 888 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
+ +R +Q+E +R ++ Q+Q+ W Q+ C+ + +K++
Sbjct: 502 KKIR---EQEEKIREQEEMMQEQE--------EKMWEQEEK--MCEQE--------EKMQ 540
Query: 948 EERERQLREEQRRQQRELMKALQQQQQQQQQ 978
E+ E+ R+E++ +++E+ L+QQ+++ Q+
Sbjct: 541 EQEEKMRRQEEKMREQEV--RLRQQEEKMQE 569
Score = 112 bits (279), Expect = 3e-24
Identities = 90/326 (27%), Positives = 172/326 (52%), Gaps = 20/326 (6%)
Query: 604 LTRQQELTALYQMQHLQYQ-QFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 662
L QQ+L A + HL + Q + + AQV + L+ QQ++++ ++ Q +
Sbjct: 245 LLPQQQLQA--EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302
Query: 663 RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGS-VWDLPLDTTTPGPALEQ 719
+I +Q +WE + + +WE + +L EQ
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREE 776
++ ++ + + +++R+E E + R+EE+ + QEE R+QEE+++ Q+E E+ ++ E
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422
Query: 777 EELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER 827
+E ++QEE +RRQ REQE +R Q E EE Q+QEE + E + E+E +
Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Query: 828 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886
++QEE +R+QEE+ + ++ E + ++ E M+E+ ++ +EE+ +E ++Q Q
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 542
Query: 887 KELM-RQRQQQQEALRRLQQQQQQQQ 911
+E M RQ ++ +E RL+QQ+++ Q
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 85.9 bits (211), Expect = 2e-16
Identities = 80/325 (24%), Positives = 162/325 (49%), Gaps = 37/325 (11%)
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERKRREE 776
+++L K + A + R + +E+ K QE+L+ ++ EI +E +RK
Sbjct: 183 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 242
Query: 777 EELARRKQEEALRRQREQEIA-----LRRQREEEE-----RQQQEEALRRLEERRREEEE 826
+ L ++Q +A +E+ L+ Q EE E QQQEE + R EE+ +E EE
Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302
Query: 827 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE--EEERKRKELE-- 882
+ +++QEE+ RE+EE RR EE EE+ R E+E K +ELE
Sbjct: 303 K------IQEQEEKI----REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 883 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQM-----KLPSSSTWGQQSNTTACQSQAT 937
+ Q+++ Q +++QE + +Q+++Q+Q A+M K+ ++ + +
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
+ E + E+E E Q +EE+ R+Q E ++ +++ ++Q++K+ + +
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE----- 467
Query: 998 EIQQEEARQMQKQQQQQQQHQQPNR 1022
++ ++E + +++ + Q+Q ++ R
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRR 492
Score = 61.2 bits (147), Expect = 6e-09
Identities = 64/324 (19%), Positives = 136/324 (41%), Gaps = 90/324 (27%)
Query: 775 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 808
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 809 -------------------QQEEALRRLEERRRE------------------EEERRKQE 831
Q+++A R +EE +E +E+ K +
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215
Query: 832 ELLRKQEEEAAKWAREEEEAQRRLEENRL-----RMEEEAARLRHE------------EE 874
E L+ E E ++ +E +R+LE +L +++ EA L E EE
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMKLPSSSTWGQQSNTTAC 932
L Q+++++ RQ ++ QE ++Q+Q++ ++Q +M+ W ++
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992
+ +I++LEE+ Q + ++ ++R+ + +++Q+++Q+Q+ W K
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK---- 391
Query: 993 TKSLLEIQQEEARQMQKQQQQQQQ 1016
+ Q+E+ R+ ++ Q+Q++
Sbjct: 392 ----IREQEEKIREQEEMMQEQEE 411
Score = 40.8 bits (94), Expect = 0.008
Identities = 74/411 (18%), Positives = 157/411 (38%), Gaps = 66/411 (16%)
Query: 863 EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 922
+E+ A +H+E R+ E +VQ + L Q+ + Q AL Q +Q + L S
Sbjct: 97 DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 155
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 975
S A + + LS QK + +R +L +E+ EL + L+++ +
Sbjct: 156 --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 213
Query: 976 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
Q+KL + L+ + E A+ + QQQ Q + + + + L +
Sbjct: 214 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 1036 -GNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1094
N +W N N+ +
Sbjct: 274 EENELW-------------------------------------------NRLNQQQEEKM 290
Query: 1095 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1154
+ + R+ K E+EEK+ + + + + ++ + E+M +
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-----EK 345
Query: 1155 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1214
++E+E + IR E ++ +Q E+R +Q+A RQ++++ +Q+++ Q+
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 1215 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVR 1265
+ Q+Q+ G +++ + +Q Q K ++++K +R
Sbjct: 404 --EMMQEQEEKMGEQE---EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Score = 34.3 bits (77), Expect = 0.79
Identities = 42/207 (20%), Positives = 90/207 (43%), Gaps = 14/207 (6%)
Query: 154 EMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIF------ 207
+MH + E+ ++R E+ ++ + +E + R+ E IR + E R
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKIREQEEMMQE 408
Query: 208 REEQNGEDEDGGWRLAGSRRDGE-RWRPHSPGWREHMERRRRFEFDFRDRDDERGYRRVR 266
+EE+ GE E+ W ++ E + R RE ++ R E R++++ + +
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Query: 267 SGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-KVQKEPIPEEQEMDFRPVDEG 325
G + + E +++ EE+M + K + Q+E I E++EM ++
Sbjct: 469 MGE---QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 326 EECSDSEGSHNEEAKEPDKTNKKEGEK 352
E + E+ +E ++ +++ EK
Sbjct: 526 WEQEEKMCEQEEKMQEQEEKMRRQEEK 552
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 135 bits (340), Expect = 3e-31
Identities = 118/463 (25%), Positives = 233/463 (50%), Gaps = 59/463 (12%)
Query: 603 RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 662
RL +QQE Q + +Q + IQ+Q ++ Q++K ++ ++ ++ + + KM
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 351
Query: 663 RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGS-VWDLPLDTTTPGPALEQ 719
R ++ + + + +WE + + +WE + +L EQ
Sbjct: 352 RRQEEMMWEKEEKMRRQEEM--MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---------EE 770
++ ++ + + +++R+E E + R+EE+ + QEE R+QE+ + RQ+E EE
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 771 RKRREEEELARRK------------------QEEALRRQRE----QEIALRRQRE----- 803
KR+E+EE+ R++ QEE +R+Q E QE +R Q E
Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 804 EEERQQQEEALRRLEERRREEEERRKQEELL---RKQEEEAAKWAREEEEAQRRLEENRL 860
EE+ +QEE +R EE REEE+ +QE++ ++QE+E W +EE R EE
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW--RQEEKIREQEEKVW 587
Query: 861 RMEEEAARLRHEEEERKRKELEVQRQKELMRQR----QQQQEALRRLQQQQQQQQLAQMK 916
R EE ++R +EE+R+ +E ++ +Q+E +R++ Q+Q+E +R +++ ++Q+ +M
Sbjct: 588 RQEE---KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE--EMT 642
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
G+Q Q + E +EE+ R+ +E++ R+Q E ++ ++ Q+Q
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE-QEKKIREQEEKIREQEEMMQEQ 701
Query: 977 QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019
++K+ W K + + E +++ RQ +K +Q+ + +Q
Sbjct: 702 EEKM--WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Score = 122 bits (307), Expect = 2e-27
Identities = 103/408 (25%), Positives = 207/408 (50%), Gaps = 64/408 (15%)
Query: 601 QERLTRQQELT-----ALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQ 655
+E++ RQ+E+ + +++ ++Q I++Q + +++K ++Q+Q A + +
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWR 434
Query: 656 QFQTLKMRISDQNIIPSVTR----SVSVPDTGSIWELQPTASQPTVW-------EGGSVW 704
Q + K+R ++ I + + + I E + Q +W E +W
Sbjct: 435 QEE--KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 705 DLPLDTTTPGPALEQLQQLEKA--KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI 762
EQ +++ K K + E++ RE E + + +EE+ RQEE R+QEE+
Sbjct: 493 ------RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546
Query: 763 LRRQQEEERKRREEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEA 813
R +++ + + EE R++QE+ + RQ REQE + RQ E EE+RQ+QEE
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 814 LRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
+ + EE+ RE+EE+ ++QEE +R+QEE+ + +E + ++ E +M E+ +++ +
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
EE R+E +++ Q++ +R+ Q+E +R ++ Q+Q+ W Q+
Sbjct: 667 EETMWRQEEKIREQEKKIRE---QEEKIREQEEMMQEQE--------EKMWEQEE----- 710
Query: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 980
+ E+E + Q +EE+ R+Q E M + + +QQ++K+
Sbjct: 711 -----------KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
Score = 109 bits (272), Expect = 2e-23
Identities = 82/307 (26%), Positives = 165/307 (53%), Gaps = 45/307 (14%)
Query: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
+QE + RQ+E +++ + + Q+ + +Q ++ Q++K ++ ++ Q
Sbjct: 474 EQEEMWRQEE--KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE--------QE 523
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIW-ELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 718
K+R ++ + + + + +W E + Q +WE E
Sbjct: 524 EKIREQEEKMW---RQEEKIREQEEMWREEEKMHEQEKIWE------------------E 562
Query: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE--- 775
+ +Q ++ K + E++ RE E + R+EE+ + QEE R++QEE + +Q+E+ R++ E
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 776 EEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEE 826
E+E R+QEE +R Q +EQE + Q E EE+ Q+QEE + R EE+ RE+E+
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 827 R-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 885
+ R+QEE +R+QEE + + E + ++ E +M+E+ ++R +EE+ +E+ +++
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Query: 886 QKELMRQ 892
Q+E M++
Sbjct: 743 QEEKMQE 749
Score = 105 bits (262), Expect = 3e-22
Identities = 67/209 (32%), Positives = 126/209 (60%), Gaps = 14/209 (6%)
Query: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKR 773
+ + +++ + + EQE+ E + + +E++ RQEE R+QEE + RQ+E E+ ++
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
Query: 774 REEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREE 824
R+E+E KQEE +R Q +EQE +R Q E EE Q+QEE + EE+ E+
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
Query: 825 EER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 883
EE+ ++QEE + +QEE+ + ++ E + ++ E M+E+ ++ +EE+ +E ++
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Query: 884 QRQKELMRQRQQQQ-EALRRLQQQQQQQQ 911
Q Q+E MR+++++ E RL+QQ+++ Q
Sbjct: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 101 bits (251), Expect = 5e-21
Identities = 116/561 (20%), Positives = 249/561 (44%), Gaps = 73/561 (13%)
Query: 705 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 764
+L +T T E+ +L++ K +E E+ E ++ K + + +R + L QQ+
Sbjct: 208 ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 262
Query: 765 RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 823
Q E + +E + ++ + Q + E E+ R Q++EE+ +QEE ++ EE+ +E
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318
Query: 824 EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 865
+EE+ R+QEE +R+QEE E W +EE EE RR EE EE+
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Query: 866 AARLRHE--EEERKRKELE--VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
R E+E K +ELE + Q+++ Q +++QE + +Q+++Q+Q A+M
Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 922 TWGQQSNTTACQS---QATLSLAEIQKLEEERERQLREEQRRQQ----------RELMKA 968
Q+ + + + E +K+ EE +RQ +EE RQ+ R+ K
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM 498
Query: 969 LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTH 1028
+Q+++ ++Q+ W K + + E +++ RQ +K ++Q++ ++ +
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ-- 556
Query: 1029 SNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNAD-TKNSNMGFW--DDAVKEVGPRNS 1085
+W + + +W + + W ++ ++E +
Sbjct: 557 --------EKIW-------EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Query: 1086 TNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANN 1145
+ K + K Q +K++E+E+ ++ + + Q+ TQ E+ +
Sbjct: 602 EQEEK----MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE---KMGEQEE 654
Query: 1146 LDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQ 1205
++ E+ + + IR E +E ++ E +Q+ Q++++ +
Sbjct: 655 KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714
Query: 1206 QQQQQPPQQPPQQPQQQDSVW 1226
Q+++ Q+ + +Q++ +W
Sbjct: 715 QEEKMQEQEEKMR-RQEEKMW 734
Score = 85.5 bits (210), Expect = 3e-16
Identities = 95/546 (17%), Positives = 227/546 (41%), Gaps = 49/546 (8%)
Query: 730 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 789
+L +ER + R + +E + +E L+ + E+ + + + +RK E A
Sbjct: 197 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 256
Query: 790 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR-KQEEEAAKWAREE 848
+Q++ +E Q L+ E +Q+E +QEE+ +W +
Sbjct: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316
Query: 849 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ 908
+E + ++ E ++ E+ ++R +EE KE +++RQ+E+M +++++ R Q++
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM----RRQEEMM 372
Query: 909 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER--ERQLREEQRRQQRELM 966
++ +M+ W ++ + + +I++ EE+R E ++RE+++RQ++E
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 967 ------KALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020
K +Q+++ ++Q+ W K K E +++E +M +Q+++ + ++
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Query: 1021 NRARNNTHSNLH--TSIGNSVW-GSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAV 1077
R + H VW + + +W + W +
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 1078 KEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQML 1137
K + K K RQ +K+ E+E+ K+++ K ++ + EQ
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMW----RQEEKIREQEE--KVWRQEEKIREQEEKRQEQ-- 603
Query: 1138 HALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQ 1197
E ++ + IR E +E ++ E+ +Q+ Q
Sbjct: 604 --------------------EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 1198 RQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKK 1257
Q++++ +Q+++ Q+ Q +Q++++W Q + Q+ + +
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQ-EQEETMWRQEEKIRE---QEKKIREQEEKIREQEEMMQ 699
Query: 1258 KKKQKM 1263
++++KM
Sbjct: 700 EQEEKM 705
Score = 57.4 bits (137), Expect = 9e-08
Identities = 97/548 (17%), Positives = 214/548 (39%), Gaps = 97/548 (17%)
Query: 775 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 808
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 809 --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 856
+ E+AL + ++++ EE K+ + L + E +E +L+
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 857 ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916
E +E E + ++ +E KRK ++R K L+ Q+Q Q EA ++ Q Q +
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERER-QLREEQRRQQRELMKALQQQQQQ 975
+ + W + + Q Q + +K++E E+ Q +EE+ R+Q E K +Q+++
Sbjct: 285 VEENELWNRLN-----QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE--KIREQEEKM 337
Query: 976 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
++Q+ W K + E+ E+ +M++Q++ + ++ R +
Sbjct: 338 RRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE---------- 383
Query: 1036 GNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASL 1095
+W + +L + + + +E R + + A +
Sbjct: 384 -EMMW------EKEEKIRELEEKMHEQEKIREQE----EKRQEEEKIREQEKRQEQEAKM 432
Query: 1096 SKSVGVSNRQNKKVEEEEKLL-----KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPT 1150
+ Q +K+ E+EK + K+ + ++ Q E+M + +
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE--- 489
Query: 1151 FVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ--- 1207
++ E +E + IR +E ++ E+ +Q+ RQ++++ +Q+
Sbjct: 490 --EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 1208 -------QQQPPQQPPQQPQQQDSVWGMNHSTL---HSVFQTNQSNNQQSNFEAVQSGKK 1257
+Q+ + ++ +Q+D +W V++ + +Q Q K
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Query: 1258 KKKQKMVR 1265
K+++ +R
Sbjct: 608 WKQEEKIR 615
Score = 45.1 bits (105), Expect = 4e-04
Identities = 59/276 (21%), Positives = 111/276 (40%), Gaps = 36/276 (13%)
Query: 153 REMHRSQSWEERGDRRFEKPGRKDVGRPNFEEG---GPTSVGRKHEFIRSESENWR---- 205
R+ + EE+ ++ EK R++ EE + R+ E IR + E WR
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 206 ------IFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPGWREHMERRRRFEFDFRDRD 257
I+ EE+ E ED WR R+ E WR RE E+R+ E ++
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK-IREQEEKRQEQEEKMWKQE 611
Query: 258 DERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEM 317
+ ++R I + + + E + E+E + + Q+E + E++E
Sbjct: 612 E-----KIREQEEKIQEQEEKIREQEEKIREQE-----------EMTQEQEEKMGEQEEK 655
Query: 318 DFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTP 377
++ +E ++ E+ +E +K +++ EK R E +E +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI-REQEEMMQEQEEKMWEQEEKMCE 714
Query: 378 SDHQSQEASQFERKDEPKTEQTE---KAEEETRMEN 410
+ + QE + R+ E K + E + +EE E+
Sbjct: 715 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 134 bits (338), Expect = 4e-31
Identities = 133/575 (23%), Positives = 263/575 (45%), Gaps = 73/575 (12%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE----EERKR 773
E ++LE+AK + + + R+EEE + QE+ R+QEE + RQ+E +E K
Sbjct: 212 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
Query: 774 REEEELARRKQEEALRRQ----REQEIALRRQR----EEEERQQQEEALRRLEERRREEE 825
RE+EE RR QE+ LR Q REQE LR Q+ +EE+ Q+QEE + EE+ RE+E
Sbjct: 272 REQEEKMRR-QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 826 ERR-KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
E+ +QEE L +QE++ RE+E+ R EE RM E+ RLR E+EER R++ ++
Sbjct: 331 EKMWRQEERLWEQEKQM----REQEQKMRDQEE---RMWEQDERLR-EKEERMREQEKMW 382
Query: 885 RQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMKLPSSSTWGQQSNTTACQS--QATLSL 940
Q+E M++ ++ +E ++++++++ ++Q +M+ + W Q+ Q + L
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 941 AEIQKLEEERERQLREEQRRQQRELM----KALQQQQQQQQQKLSGWGNVSKPSGTTKSL 996
E +K++E+ E+ +E++ + +E M K + +Q++ ++Q+ W
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW------------- 489
Query: 997 LEIQQEEARQMQKQQ---QQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS 1053
+QEE + Q+Q+ Q+++ +Q R R W
Sbjct: 490 ---EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK--------------KMWQQ 532
Query: 1054 DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE 1113
+ + T+ WD K R + + + + Q +K++E+E
Sbjct: 533 E--EKMREEKKTQEQEKKTWDQEEKM---REEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 1114 KLL-----KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYI 1168
+ + K+++ K Q+ + EQ + + E E + +
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 1169 RAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGM 1228
+ +E + E + + + + R+Q++ Q Q+++ +Q + Q++ +WG
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Query: 1229 NHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1263
+ + E ++ K+K ++++
Sbjct: 708 EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Score = 127 bits (320), Expect = 5e-29
Identities = 118/493 (23%), Positives = 234/493 (47%), Gaps = 84/493 (17%)
Query: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
+QE R+QE Q + L+ Q+ +++Q ++ Q++ Q Q+Q + +Q +
Sbjct: 266 EQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE- 324
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA---SQPTVWEGGSVWDLPLDTTTPGPA 716
KMR ++ + R +WE + Q + +W+
Sbjct: 325 -KMREQEEKMWRQEER---------LWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374
Query: 717 LEQLQQLEKAKAAKLEQER-REAEMRAKREEEERKRQEELRRQQEEILRRQQEEE----- 770
+ + +++ + + E+ER RE E + + EEE + QEE ++QEE + Q+E+E
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 771 ----------RKRREEEELARRKQEEALRRQRE---QEIALRRQ---REEEERQ------ 808
+++ +E+E +QEE +R Q E QE + RQ RE+E++
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 809 ----------------QQEEALRRLEERRREEEERRKQEELLRK----QEEEAAKWAREE 848
+Q+E LR EER RE+++ +QEE +R+ QE+E W +EE
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
Query: 849 E-EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM-RQRQQQQEALRRLQQQ 906
+ + R+ E +M EE +R +EE+ + +E +++ Q+E M Q ++ QE ++ +Q
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Query: 907 Q----QQQQLAQMKLPSSSTWG-----QQSNTTACQSQATLSLAEIQKLEEERERQLREE 957
+ +Q++ +M+ W Q+ + + + E + E+E + Q +EE
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Query: 958 QRRQQRELMKALQQQQQQQQQKLSG-----WGNVSKPSGTTKSLL---EIQQEEAR---Q 1006
+ R+Q E M+ +++ ++Q++K+ G WG K G + + E++++E R Q
Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Query: 1007 MQKQQQQQQQHQQ 1019
+K Q++ +H++
Sbjct: 735 KEKMQERLPEHEE 747
Score = 125 bits (313), Expect = 3e-28
Identities = 113/469 (24%), Positives = 223/469 (47%), Gaps = 79/469 (16%)
Query: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
+QE+ R+QE Q + L+ Q+ +++Q ++ Q+++ L Q+++ + +
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR--LREQEKELREQEKELREQ 302
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R ++ + + + E + + +WE ++
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE------------------QE 344
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ---EEERKRREE 776
Q E+ + + ++ER + RE+EER R++E +QEE ++ ++ E E+K REE
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 777 EELAR------RKQEEALRRQREQEIALRRQREEEER-------QQQEEALRRLEERRRE 823
EE R +KQEE + Q E+E +R E++E+ Q+QEE + EE+ R+
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464
Query: 824 EEE-------------RRKQEELLRKQEE-----EAAKWAREEE--EAQRRLEENRLRME 863
+EE R+QE+ + +QEE E W +EE E RL E RM
Sbjct: 465 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524
Query: 864 EEAARLRHEEEERKRKELEVQ-----------RQKELMRQRQ---QQQEALRRLQQQQQQ 909
E+ + EE+ R+ K+ + Q R++E MR+R+ +++E + R Q+++ Q
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 910 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 969
+Q +M+ W Q+ Q Q + +K+ E+ E E++ ++Q E+M
Sbjct: 585 EQEEKMREQEEKMWEQEEK---MQEQEEKMWEQEEKMWEQEE----EDKMQEQEEMMWEQ 637
Query: 970 QQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
+++ Q+Q++K+ W K + + E +++ Q +K ++Q+++ Q
Sbjct: 638 EEKMQEQEEKM--WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Score = 102 bits (254), Expect = 2e-21
Identities = 91/333 (27%), Positives = 164/333 (49%), Gaps = 41/333 (12%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E Q+RL Q+E L++ + +Q Q+ I +Q ++ Q++ + +Q + Q+
Sbjct: 429 EWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 658 QTL----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGSVWDLPLDTT 711
Q KMR +Q + R +WE + + E +W
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEER---------MWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 712 TPGPALEQLQQLEKAKAAKLEQER-REAEMRAKREEEERKRQEELRRQQEEILRRQ---- 766
EQ ++ + E+ER RE E + + EEE + QEE ++QEE +R Q
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 767 -------QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE 819
QE+E K E+EE ++EE +++E+ + +EE+ Q+QEE + EE
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM----WEQEEKMQEQEEKMWEQEE 653
Query: 820 RRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 878
+ RE+EE+ R+QEE ++ QEE+ RE+EE + EE +M E+ ++R +EE+
Sbjct: 654 KMREQEEKMREQEEKMQGQEEK----MREQEEKMQGQEE---KMREQEEKMRGQEEKMWG 706
Query: 879 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 911
+E ++ Q+E M +++ +E R++ Q+++ Q
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Score = 92.4 bits (228), Expect = 2e-18
Identities = 97/553 (17%), Positives = 233/553 (42%), Gaps = 68/553 (12%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
AL + K +E+ +E + + EEL+++ E+ +E+ + E
Sbjct: 146 ALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL-----QEKLRLAE 200
Query: 776 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 835
E+ + + L+R+ E+ L Q + QEE R+ EE R +E++ RKQEE +
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 258
Query: 836 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 895
+QEE E+E + R +E ++R +E+ RLR +E+E + +E E++ QK+L Q +Q
Sbjct: 259 RQEERL-----REQEGKMREQEEKMRRQEK--RLREQEKELREQEKELREQKKLREQEEQ 311
Query: 896 QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 955
QE ++ +Q+++ + + K+ W Q+ ++L E+
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKM-----WRQE-----------------ERLWEQ------ 343
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQ 1015
E+Q R+Q + M+ +++ +Q ++L + E QEE R +++++ ++
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 1016 QHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDD 1075
+ + ++W Q + +W + W+
Sbjct: 404 EEETMREQEEKMQKQ-----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458
Query: 1076 AVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQ 1135
K + K + + + ++++ E+EEK+ Q + ++ + E+
Sbjct: 459 EEKIRDQEEMWGQEK---KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 1136 MLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAK----EFAKQFLERRAK 1191
+ ++E + ++ + +R + K + K E R +
Sbjct: 516 LREKEER------------MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 1192 QKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEA 1251
++ + R+++++ ++Q+++ +Q + +Q++ +W + ++ +E
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEKMWEQEEKMWEQ 621
Query: 1252 VQSGKKKKKQKMV 1264
+ K +++++M+
Sbjct: 622 EEEDKMQEQEEMM 634
Score = 66.2 bits (160), Expect = 2e-10
Identities = 79/375 (21%), Positives = 164/375 (43%), Gaps = 34/375 (9%)
Query: 477 DDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQ 536
++EE ++ E++ +K + + + E +L E + K M E +K + ++ +
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 537 GEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHM 596
Q QE W Q M + ++ + KMW + M
Sbjct: 462 IRDQEEMWGQEKKMWRQE---KMREQEDQMWEQEEKMRDQEQKMWDQ---------EERM 509
Query: 597 GELDQ---ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALL 653
E D+ E+ R +E ++Q + ++ Q+Q + Q++K + +++ +
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 654 LQQFQTL-----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPL 708
++ + + KM+ ++ + + + E + + +WE +
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
Query: 709 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 768
E++Q+ E+ K + E++ RE E + + +EE+ + QEE R+QEE + Q +
Sbjct: 630 QEEMMWEQEEKMQEQEE-KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE--KMQGQ 686
Query: 769 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 828
EE+ R +EE++ R QEE + Q E + +EE+ +E +R EER R+++E
Sbjct: 687 EEKMREQEEKM--RGQEEKMWGQEE------KMWGQEEKMWGQEEMREKEERIRDQKE-- 736
Query: 829 KQEELLRKQEEEAAK 843
K +E L + EE ++
Sbjct: 737 KMQERLPEHEERCSE 751
Score = 58.5 bits (140), Expect = 4e-08
Identities = 90/508 (17%), Positives = 196/508 (38%), Gaps = 51/508 (10%)
Query: 775 EEEELARRKQEEALRRQREQE------IALRRQREEEERQQQEEALRRLEERRREEEERR 828
E+E+ A + +EALRR+ E + + ++ E ++A R+ E+ E +
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 829 KQE--------ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 880
L++ + W ++ + L + R + E R EE K+K
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
Query: 881 LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 940
E+ Q++L ++ E +++ +++ + A+ LP T Q + +
Sbjct: 190 AEL--QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
Query: 941 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
+I+K EE+ RQ EE+ R+Q M+ +++ ++Q+++L + K L E +
Sbjct: 248 KKIRKQEEKMWRQ--EERLREQEGKMREQEEKMRRQEKRLREQEKELREQ--EKELREQK 303
Query: 1001 QEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVW-GSINTGPPNQWASDLVSSI 1059
+ ++ Q Q+Q+++ +Q + R +W Q D +
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE--ERLWEQEKQMREQEQKMRDQEERM 361
Query: 1060 WSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLF 1119
W + KE R + + + + R+ K EEEE + +
Sbjct: 362 WEQDERLRE---------KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412
Query: 1120 QGVNKAQDGF-----TQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1174
+ + K ++ +W +Q L P L E E E + I
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRL-----------PEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 1175 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLH 1234
+ +E Q E++ ++ + Q+ Q+ +Q+++ Q+ + Q++ +W +
Sbjct: 462 IRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQEEKMRDQE-QKMWDQEERMWEQDERLRE 518
Query: 1235 SVFQTNQSNNQQSNFEAVQSGKKKKKQK 1262
+ + E ++ KK ++Q+
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQE 546
Score = 44.3 bits (103), Expect = 8e-04
Identities = 43/226 (19%), Positives = 94/226 (41%), Gaps = 16/226 (7%)
Query: 190 VGRKHEFIRSESENW----RIFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPGWREHM 243
+ + E IR + E W +++R+E+ E ED W RD E+ W W +
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 244 ERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSL 303
R + E R R+ ++ +++ W D EE+M +
Sbjct: 515 RLREKEE---RMREQKKMWQQEEKMREEKKTQEQEKKTW---DQEEKMREEERMREREKK 568
Query: 304 KKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEE 363
+ ++E + E++E + ++ E+ + E E+ ++ + +K E+ +++ E EE
Sbjct: 569 MREEEEMMREQEE---KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW-EQEEE 624
Query: 364 TPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRME 409
Q QE +E++++ + ++ + E+E +M+
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 134 bits (337), Expect = 6e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 602 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 661
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 193 EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
Query: 662 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 712
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
Query: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 772
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
Query: 773 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 827
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 828 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 874
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 932
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
Query: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 991
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 992 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1019
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 110 bits (275), Expect = 9e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 774
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 893
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 894 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 953
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Query: 954 LREEQRRQQRELMKALQQ 971
++ R ++ + A QQ
Sbjct: 605 QQDHYRGHLQQYVAAYQQ 622
Score = 97.4 bits (241), Expect = 8e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 718 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
Query: 835 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Query: 893 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Query: 947 EEERE 951
+E
Sbjct: 624 ASGKE 628
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 134 bits (337), Expect = 6e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 602 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 661
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 193 EKLTKERDALSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
Query: 662 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 712
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
Query: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 772
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
Query: 773 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 827
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 828 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 874
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 932
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
Query: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 991
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 992 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1019
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 110 bits (275), Expect = 9e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 774
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 893
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 894 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 953
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Query: 954 LREEQRRQQRELMKALQQ 971
++ R ++ + A QQ
Sbjct: 605 QQDHYRGHLQQYVAAYQQ 622
Score = 97.4 bits (241), Expect = 8e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 718 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
Query: 835 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Query: 893 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Query: 947 EEERE 951
+E
Sbjct: 624 ASGKE 628
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 134 bits (336), Expect = 7e-31
Identities = 101/332 (30%), Positives = 176/332 (53%), Gaps = 37/332 (11%)
Query: 714 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQ---- 767
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+
Sbjct: 108 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 768 EEERKRREEEELARR-------------KQEEALRRQREQ--EIALRRQREEEERQQQEE 812
E+E + RE+E R +QE + Q EQ E + Q++EE+ +QEE
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 813 ALRRLEERRREEEER-RKQEELLRKQEEEAAK---WAREEEEAQRRLEENRLRMEEEAAR 868
+R+ EE+ E+EE+ +KQEE ++KQEE+ K RE+EE R EE L+ +E+
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-- 285
Query: 869 LRHEEEERKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQ 925
+EE+ +E +++ Q+E MR++++Q QE R Q++Q +Q QM W Q
Sbjct: 286 --EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 926 QSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGN 985
+ + Q ++QK EE+ +Q EEQ R+Q E M+ ++Q ++Q++++ G
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQ--EEQMRKQEEQMRKQEEQMRKQEEQM---GE 398
Query: 986 VSKPSGTTKSLLEIQQEEARQMQKQQQQQQQH 1017
+ G K + Q+E+ + ++Q ++Q++H
Sbjct: 399 QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Score = 128 bits (322), Expect = 3e-29
Identities = 102/410 (24%), Positives = 210/410 (51%), Gaps = 45/410 (10%)
Query: 575 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVL 634
G + + G+V G +QE R+QE Q ++ Q+ +++Q QV
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
Query: 635 AQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQ 694
Q+ + +Q+ Q+ Q + + ++ +Q G + E + +
Sbjct: 126 EQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Query: 695 PTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE 754
+ G V + G Q+ + E+ + EQ +++ E ++EE+ RK++E+
Sbjct: 183 ----QEGQVRE---QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
Query: 755 LRRQQEEILRR----QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-Q 809
+ Q+E++ ++ Q++EE+ R++EE++ R+QEE +R Q EQ + + Q E+EE+ +
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQM--REQEEQMREQEEQMLKQKEQTEQEEQTGE 293
Query: 810 QEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 868
QEE +R EE+ RE+EE+ R+QEE +R+QEE+ K + E + ++ E + +M ++ +
Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
Query: 869 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 928
+ +EE+ +++E +V++Q+E MR++++Q R Q++Q ++Q QM G+Q
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQM----RKQEEQMRKQEEQM--------GEQKE 401
Query: 929 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
Q E++ + + +EEQ +Q+E M+ ++ +Q++
Sbjct: 402 ---------------QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 119 bits (299), Expect = 1e-26
Identities = 93/315 (29%), Positives = 162/315 (51%), Gaps = 51/315 (16%)
Query: 714 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
Query: 772 KRRE---EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER- 827
++ E+E +QEE + Q EQ Q++EE+ +QEE +R+ EE+ E+EE+
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 828 RKQEELLRKQEEEAAKWA---REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
+KQEE ++KQEE+ K RE+EE R EE L+ +E+ +EE+ +E +++
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMR 299
Query: 885 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 944
Q+E MR++++Q R Q++Q ++Q QM W Q+ + Q + E Q
Sbjct: 300 EQEEQMREQEEQM----REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQEEQ 353
Query: 945 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1004
E+E + Q +EEQ R+Q E M+ ++Q ++Q++
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-------------------------- 387
Query: 1005 RQMQKQQQQQQQHQQ 1019
QM+KQ++Q + ++
Sbjct: 388 -QMRKQEEQMGEQKE 401
Score = 108 bits (269), Expect = 4e-23
Identities = 88/317 (27%), Positives = 166/317 (52%), Gaps = 20/317 (6%)
Query: 714 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111
Query: 772 KRREEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER 827
E+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E +
Sbjct: 112 ----EQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQ 165
Query: 828 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886
R+QE +R+QE + + + E + ++ E +M E+ ++ +EE+ +++E ++ Q
Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
Query: 887 KELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 943
+E MR++++Q QE + Q++Q Q+Q QM+ Q+ + Q L +
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQK 282
Query: 944 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-SGWGNVSKPSGTTKSLLEIQQE 1002
++ E+E + +EEQ R+Q E M+ ++Q ++Q++++ + K E E
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 1003 EARQMQKQQQQQQQHQQ 1019
+ QM KQ++Q + ++
Sbjct: 343 QKEQMWKQEEQMGEQEE 359
Score = 105 bits (263), Expect = 2e-22
Identities = 83/318 (26%), Positives = 167/318 (52%), Gaps = 27/318 (8%)
Query: 724 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR---EEEELA 780
++ + + E + RE E + + +E + + QE R+QE +R Q+ + R++ E+E
Sbjct: 50 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109
Query: 781 RRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEELLR 835
R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE +R
Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 836 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 895
+QE + + + E + ++ E +M E+ ++ +EE+ +E ++Q+Q+E M ++++
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 896 Q----------QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK 945
Q QE + Q++Q Q+Q QM+ Q+ + Q + ++
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 946 LEE--ERERQLR--EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001
E+ E+E Q+R EEQ R+Q E M+ ++Q ++Q++++ G + K + Q+
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM---GKQEEQMWEQKEQMWEQK 344
Query: 1002 EEARQMQKQQQQQQQHQQ 1019
E+ + ++Q +Q++ Q
Sbjct: 345 EQMWKQEEQMGEQEEQMQ 362
Score = 103 bits (258), Expect = 8e-22
Identities = 82/314 (26%), Positives = 166/314 (52%), Gaps = 17/314 (5%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREE 776
E ++L+ + K E + E++ K E ++ +E + R+QE +R Q+ + R E
Sbjct: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR----E 70
Query: 777 EELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQE 831
+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE
Sbjct: 71 QEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQE 128
Query: 832 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891
+R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+ Q+ +R
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
Query: 892 QRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 948
+++ Q QE Q++Q +Q QM+ Q+ + Q ++QK EE
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
Query: 949 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1008
+ ++Q EEQ R+Q E M+ ++Q ++Q++++ ++ T E +E+ QM+
Sbjct: 249 QVQKQ--EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 1009 KQQQQQQQHQQPNR 1022
+Q++Q ++ ++ R
Sbjct: 307 EQEEQMREQEEQMR 320
Score = 92.4 bits (228), Expect = 2e-18
Identities = 75/284 (26%), Positives = 147/284 (51%), Gaps = 12/284 (4%)
Query: 745 EEEERKRQEELRRQQEEILRRQQE-EERKRREEEELARRKQEEALRRQ----REQEIALR 799
+E+ + QEEL+ + E Q +E KR+ E + QE +R Q REQE +R
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
Query: 800 RQREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEEN 858
Q E + ++QE +R E + RE+E + R+QE +R+QE + + + E + ++ E
Sbjct: 70 EQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
Query: 859 RLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ---QQQEALRRLQQQQQQQQLAQM 915
++ E+ ++R +E + + +E +V+ Q+ +R+++ ++QE R Q+ Q ++Q Q+
Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
Query: 916 KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ 975
+ Q+ + Q ++QK EE+ Q E+ R+Q+ ++ + +Q Q+Q
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQ 246
Query: 976 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019
++Q + K + E +E+ QM KQ++Q +Q +Q
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
Score = 77.4 bits (189), Expect = 8e-14
Identities = 83/454 (18%), Positives = 202/454 (44%), Gaps = 39/454 (8%)
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-QQEEALRRLEERRREEE 825
+E+ + +EE +L ++ E +E L+R+ E ++ QE +R E + RE+E
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKE----LKRKLETDKIPLPQEGQVREQEGQVREQE 65
Query: 826 ER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
+ R+QE +R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
Query: 885 RQKELMRQRQ---QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941
Q+ +R+++ ++QE R Q+ Q ++Q Q++ Q+ + Q
Sbjct: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Query: 942 EIQKLE---EERERQL--REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 996
++++ E E+E Q+ +EEQ +Q E M+ ++Q +Q++++ + G +
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242
Query: 997 LEIQQEEARQMQKQ--QQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASD 1054
++ Q+E+ ++ ++Q +Q++Q +Q + R L TG + +
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK--EQTEQEEQTGEQEEQMRE 300
Query: 1055 LVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEK 1114
+ + + +++G + + + + ++ + E+EE+
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 1115 LLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1174
+ K + V K ++ + EQM K+ E + + +
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQM------------------RKQEEQMRKQEEQMGEQKEQ 402
Query: 1175 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQ 1208
E KE ++ E+ +QK ++Q++ + +Q++
Sbjct: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 60.8 bits (146), Expect = 8e-09
Identities = 78/478 (16%), Positives = 196/478 (41%), Gaps = 89/478 (18%)
Query: 816 RLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 875
R+ +E+ QEEL + E E ++ +E +R+LE +++ + +E ++R +E +
Sbjct: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQ 60
Query: 876 RKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
+ +E +V+ Q+ +R+++ Q QE R Q+ Q ++Q Q++ Q+
Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992
+ Q +++ E+E Q+RE++ + + + + +Q+ Q ++Q+ G V + G
Sbjct: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE----GQVREQEG- 171
Query: 993 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1052
+++++E + +++ Q ++Q Q
Sbjct: 172 -----QVREQEGQVREQEGQVREQEGQMGE------------------------------ 196
Query: 1053 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112
+ MG + +++G + + + + + ++ + E+E
Sbjct: 197 -------------QEGQMG---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 1113 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1172
E++ K + V K ++ + EQM ++ E E + +
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMR------------------EQEEQMREQEEQMLKQK 282
Query: 1173 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1232
T + ++ +Q E + +++ Q R+Q++ ++Q++Q +Q Q +Q++ +W
Sbjct: 283 EQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Query: 1233 LHSV----FQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGE 1286
Q Q Q+ + + +K++++M + + + + MGE
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Score = 33.1 bits (74), Expect = 1.8
Identities = 56/294 (19%), Positives = 111/294 (37%), Gaps = 19/294 (6%)
Query: 150 GGGREMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFRE 209
G RE +E R E R+ G+ +EG R+ E E E +E
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV----REQEGQVREQEGQVREQE 121
Query: 210 EQNGEDEDGGWRLAGSRRDGE-RWRPHSPGWREHMERRRRFEFDFRDRD----DERGYRR 264
Q E E G R+ E + R RE + R E R+++ ++ G R
Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
Query: 265 VRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDE 324
+ G + + E + + EE+MG + ++K +++ +E++M +
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQM 236
Query: 325 GEECSDSEGSHNEEAKEPDKTNK-----KEGEKTDRVGVEASEETPQTSSSSARPGTPSD 379
GE+ + + K+ ++ K +E E+ R E + + + + G +
Sbjct: 237 GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
Query: 380 HQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQ 433
++ Q ++E EQ E+ E+ ++ + ++M +Q Q
Sbjct: 297 QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 127 bits (320), Expect = 5e-29
Identities = 105/431 (24%), Positives = 215/431 (49%), Gaps = 75/431 (17%)
Query: 603 RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 662
RL +QQE Q + +Q + IQ+Q ++ Q++K ++ ++ ++ + + KM
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 351
Query: 663 RISDQNIIPSVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGPALEQL 720
R ++ +WE + + +WE E++
Sbjct: 352 RRQEE----------------MMWEKEEKMRRLEEMMWEKE----------------EKI 379
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
++LE+ K+ ++ + E KR+EEE+ R++E R++QE + RQ EE+ R +EE++
Sbjct: 380 RELEE----KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKI- 432
Query: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALR------------RLEERRREEEERR 828
R+QE+ + RQ E+ + REEE+RQ+QEE R R +E+ E+E+ R
Sbjct: 433 -REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 829 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 888
KQEE + +QEE+ ++EE R EE R EE ++R +EE+ + +E +++ Q+E
Sbjct: 492 KQEEKVWRQEEK----MHDQEEKIREQEEKMWRQEE---KIREQEEKIREQEEKIREQEE 544
Query: 889 LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 948
+M++++++ Q+Q++ + + K+ ++ + + + E + E+
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ 604
Query: 949 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1008
E Q +EE+ +Q E M +++ Q+Q++K+ + E E+ +++
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM-------------RRQEEKMWEQEVRLR 651
Query: 1009 KQQQQQQQHQQ 1019
+Q+++ Q+HQ+
Sbjct: 652 QQEEKMQEHQE 662
Score = 122 bits (305), Expect = 3e-27
Identities = 93/339 (27%), Positives = 183/339 (53%), Gaps = 40/339 (11%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER------ 771
E++++ E+ K E+ RR EM ++EE+ R+ +E++ +QE+I R+QEE+R
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-EQEKI--REQEEKRQEEEKI 405
Query: 772 ---KRREEEELARRKQEEALRRQ----REQEIALRRQRE---EEERQQQEEALRRLEERR 821
++R+E+E +QEE +R Q REQE + RQ E E+E+ ++EE + EE
Sbjct: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 822 REEEERRKQEELLRKQEE--EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 879
R+EE+ R+QEE+ R++E+ E K ++EE+ R+ E +M ++ ++R +EE+ R+
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE----KMHDQEEKIREQEEKMWRQ 521
Query: 880 ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLS 939
E +++ Q+E +R +Q+E +R ++ Q+Q+ G+Q Q +
Sbjct: 522 EEKIREQEEKIR---EQEEKIREQEEMMQEQE---------EKMGEQEEKMQEQEKMRRQ 569
Query: 940 LAEIQKLEE---ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 996
+I++ EE E++ ++RE++ + + K +Q++ Q+Q+ W K + +
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629
Query: 997 LEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
E +++ RQ +K +Q+ + +Q +L +I
Sbjct: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 120 bits (301), Expect = 8e-27
Identities = 93/327 (28%), Positives = 174/327 (53%), Gaps = 43/327 (13%)
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQ-----------QEE 769
QQ +A+A L +E + + + + EE + L +QQEE + RQ QE+
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 770 ERKRREEEELARRKQEEALRRQR----EQEIALRRQRE-----EEERQQQEEALRRLEER 820
E K RE+EE R+QEE +RRQ E+E +RRQ E EE+ ++ EE + EE+
Sbjct: 320 EEKIREQEEKI-REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 880
RE EE+ ++E +R+QEE+ R+EEE ++ E R E+EA R EE+ R+++E
Sbjct: 379 IRELEEKMHEQEKIREQEEK-----RQEEE---KIREQEKRQEQEAKMWRQEEKIREQEE 430
Query: 881 LEVQRQKELMRQRQQ--QQEALRRLQQQQQQQQLAQMK---LPSSSTWGQQSNTTACQSQ 935
+++K++ RQ ++ +QE +R +++Q+Q+++ + + W Q+ Q
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK---MHEQ 487
Query: 936 ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKS 995
+ E + +E + +EE+ R+Q E M +++ ++Q++K + + +
Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK------IREQEEKIRE 541
Query: 996 LLEIQQEEARQMQKQQQQQQQHQQPNR 1022
E+ QE+ +M +Q+++ Q+ ++ R
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Score = 100 bits (249), Expect = 9e-21
Identities = 86/338 (25%), Positives = 175/338 (51%), Gaps = 40/338 (11%)
Query: 705 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 764
+L +T T E+ +L++ K +E E+ E ++ K + + +R + L QQ+
Sbjct: 208 ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 262
Query: 765 RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 823
Q E + +E + ++ + Q + E E+ R Q++EE+ +QEE ++ EE+ +E
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318
Query: 824 EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 865
+EE+ R+QEE +R+QEE E W +EE EE RRLEE EE+
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Query: 866 AARLRHE--EEERKRKELEVQRQKELMR--QRQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
L + E+E+ R++ E ++++E +R +++Q+QEA Q+++ ++Q +++
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438
Query: 922 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK---ALQQQQQQQQQ 978
W Q+ + + E +K +E+ E +EE+ R+Q E+ + + +Q++ ++Q
Sbjct: 439 MWRQEEKIHEQE-----KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 979 KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1016
+ W K + + E +++ RQ +K ++Q+++
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531
Score = 60.1 bits (144), Expect = 1e-08
Identities = 91/510 (17%), Positives = 204/510 (40%), Gaps = 80/510 (15%)
Query: 775 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 808
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 809 --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 856
+ E+AL + ++++ EE K+ + L + E +E +L+
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 857 ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916
E +E E + ++ +E KRK ++R K L+ Q+Q Q EA ++ Q Q +
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 917 LPSSSTW---GQQSNTTACQSQATLSLAE--IQKLEE---ERERQLREEQRRQQRELMKA 968
+ + W QQ + + + E IQ+ EE E+E ++RE++ + +R+
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 969 LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ------QEEARQMQKQQQQQQQHQQPNR 1022
+++++ ++Q+ W K + + E + +E+ + +K ++Q+++ Q+ +
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 1023 ARNNTHSNLHTSIGNSVW-GSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVG 1081
R + +W + + +W + + + ++E
Sbjct: 405 IREQEKRQEQEA---KMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-----QEKIREEE 456
Query: 1082 PRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALN 1141
R + + RQ +K+ E+EK+ K + V + ++ E++
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
Query: 1142 TANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQ---- 1197
++ E E + IR E +E ++ E+ +Q+ Q
Sbjct: 517 -----------KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 1198 -RQQQQLPQQQQQQPPQQPPQQPQQQDSVW 1226
R+Q++ ++Q+++ +Q + +Q++ +W
Sbjct: 566 MRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/220 (24%), Positives = 98/220 (44%), Gaps = 65/220 (29%)
Query: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
DQE R+QE Q + ++ Q+ I++Q ++ Q++ + +Q++++ ++ Q
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE---MMQEQEEKMGEQEEKMQE 562
Query: 660 L-KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 718
KMR ++ I
Sbjct: 563 QEKMRRQEEKI------------------------------------------------- 573
Query: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ----EEERKRR 774
+Q EK + K ++ RE E + +EE+ + QEE+ ++QEE + Q+ E+E K +
Sbjct: 574 -REQEEKIREQK--EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREE-EERQQQEEA 813
E+EE RR++E + EQE+ LR+Q E+ +E Q+ EA
Sbjct: 631 EQEEKMRRQEE----KMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 42.7 bits (99), Expect = 0.002
Identities = 73/410 (17%), Positives = 162/410 (39%), Gaps = 49/410 (11%)
Query: 863 EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 922
+E+ A +H+E R+ E +V + L Q+ + Q AL Q +Q + L S
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 167
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 975
S A + + LS QK + +R +L +E+ EL + L+++ +
Sbjct: 168 --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
Query: 976 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
Q+KL + L+ + E A+ + QQQ Q + + + + L +
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1036 G-NSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1094
N +W +N + +W + W++ ++E + + K
Sbjct: 286 EENELWNRLNQQQEEK--------MWRQEEKIQE----WEEKIQEQEEKIREQEEKIREQ 333
Query: 1095 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1154
K RQ + + E+E+ ++ + + ++ + E+M+
Sbjct: 334 EEKM----RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK----------- 378
Query: 1155 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1214
++E+E + IR E ++ +Q E+R +Q+A RQ++++ +Q+++ Q+
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 1215 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q++ +H + + +Q E + +K ++Q+ +
Sbjct: 437 KKMWRQEE---------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Score = 37.7 bits (86), Expect = 0.072
Identities = 38/217 (17%), Positives = 90/217 (41%), Gaps = 9/217 (4%)
Query: 192 RKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPG-WREHMERRRRFE 250
R+ E + + E WR +E+ +++ WR + E+ R WR+ E+ E
Sbjct: 453 REEEKRQEQEEMWR---QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE-EKMHDQE 508
Query: 251 FDFRDRDDE--RGYRRVRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSGAFLSLKKV 306
R+++++ R ++R I + + + E +++ EE+MG + +
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Query: 307 QKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQ 366
Q+E I E++E ++ E + E+ +E ++ +++ EK + E+ +
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628
Query: 367 TSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAE 403
+ + ++ + +++E E E E
Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 120 bits (301), Expect = 8e-27
Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 36/306 (11%)
Query: 735 RREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQRE 793
+R +R +E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ +
Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQ 579
Query: 794 QEIALRRQREEEERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEE 839
+ + +EE+++Q Q +E + +E R EE+ +K + E RKQEE
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 840 EA--AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 897
EA +W ++EEE +R E + + EEE RLR E ++ E Q ++E R+ Q+++
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
Query: 898 EALRRLQQ-QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLR 955
E RR Q+ ++Q++QLA+ Q+ + QA L E +K L ++E+ R
Sbjct: 700 EQERREQERREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQR 749
Query: 956 E-EQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
E E+++++ E + ++Q Q++Q+K + +G +K+L ++ Q
Sbjct: 750 ELEEKKKKEEQQRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTP 804
Query: 1015 QQHQQP 1020
Q H+ P
Sbjct: 805 QGHRAP 810
Score = 115 bits (288), Expect = 3e-25
Identities = 87/291 (29%), Positives = 157/291 (53%), Gaps = 32/291 (10%)
Query: 688 LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLE-KAKAAKLEQERREAEMRAKREE 746
+ PT++ +V + + PL ++L+ L K +A +L +++ E + R + EE
Sbjct: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEE 565
Query: 747 EERKRQEELRR--QQEEILRRQQEEERKRREE------EELARRKQEEALRRQREQEIAL 798
+ KR+E LR+ Q E + + +EE++K+ E+ E+ + K+E + +++ A
Sbjct: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
Query: 799 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN 858
++ E E R++QEE RRL ++EEEERR QE L +K+EE E+
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----------------EQE 669
Query: 859 RLRMEEEAARLRHE-EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 917
RLR EA RL + E+ER+ +E Q ++E R+ Q+++E R+L +Q+++++ Q +L
Sbjct: 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERL 727
Query: 918 PSSSTWGQQSNTTACQ-SQATLSLAEIQKLEEER---ERQLREEQRRQQRE 964
+ ++ Q Q L E +K EE++ ERQL+EEQ ++ +E
Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 81.6 bits (200), Expect = 4e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 723 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 778
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 717
Query: 779 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 838
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 718 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
Query: 839 EEAAKWAREEEEA 851
E+ AK A +A
Sbjct: 773 EKKAKEAAGASKA 785
Score = 61.6 bits (148), Expect = 5e-09
Identities = 78/375 (20%), Positives = 163/375 (43%), Gaps = 70/375 (18%)
Query: 687 ELQPTAS-QPTVWE--GGSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM 740
E +P A+ +P V E G + W D + +TP P E A + E + +A+
Sbjct: 381 EAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK-PAASSPETPSAGQQEAKTDQAD- 438
Query: 741 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 800
RE + R+ +R ++ + EE+ EE + R K + + LR
Sbjct: 439 -GPREPPQSARR---KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
Query: 801 QREEEERQQQ------------EEALRRLEERRRE--EEERRKQEELLRKQEEEAAKWAR 846
+R Q + ++R R + E+ER++ E L RK+E E + +
Sbjct: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554
Query: 847 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 906
EE+ +RRLEE +L+ EER RK L+ + + E M++ +++Q + Q
Sbjct: 555 VEEDKRRRLEEVKLK-----------REERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
Query: 907 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE-- 964
++ ++ + +L AE + ++ +++ E + R+++E
Sbjct: 604 EKTEKAKEERL-----------------------AEEKAKKKAAAKKMEEVEARRKQEEE 640
Query: 965 --LMKALQQQQQQQ------QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1016
++ LQQ+++++ Q+K + + K L E +++E R+ ++++Q++++
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
Query: 1017 HQQPNRARNNTHSNL 1031
++ + R L
Sbjct: 701 QERREQERREQERQL 715
Score = 40.0 bits (92), Expect = 0.014
Identities = 102/524 (19%), Positives = 191/524 (36%), Gaps = 108/524 (20%)
Query: 342 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA--SQFERKDEPKTEQT 399
PD + G +TD V S P + S S QE+ + R+ KT +
Sbjct: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346
Query: 400 EKAEEE----TRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVP----- 450
A + +E L +VP + V Q+ P + A P+ P VP
Sbjct: 347 PAASGRIICHSYLERLLNVEVPQK----VGSEQKE----PPEEAEPVAAAEPEVPENNGN 398
Query: 451 ---------------NPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAY 495
NP P ETP G + D +G + Q A + +Y
Sbjct: 399 NSWPHNDTEIANSTPNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRSY 453
Query: 496 LQD-SALDDERLAS--KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN-------- 544
Q S LD+E+ +LQ R+K S P P ++ P
Sbjct: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQR 501
Query: 545 NQEMAEWFQAGYFTMSLLVKRAC-------DESFQPLGDIMKMWGRVPFSPGPAPPPHMG 597
NQ + A M +KR ++ Q L ++ +
Sbjct: 502 NQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRR 561
Query: 598 ELDQERLTRQQELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQQ 647
L++ +L R++ L + Q Q + ++ I+Q++AQ+ A++++ A ++
Sbjct: 562 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 621
Query: 648 QQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLP 707
+ A +++ + + + + + + + + + + Q + + L
Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 681
Query: 708 LDTTTPGPALEQLQQLEKAKAAKLEQERREAE--------------MRAKREEEERKR-- 751
E+ +Q E+ + + EQERRE E ++A+RE +ER++
Sbjct: 682 EQREQERREQERREQ-ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 740
Query: 752 ---QEELRRQQEE---------ILRRQQEEERKRREEEELARRK 783
+E+L+R+ EE + RQ +EE++++ +E K
Sbjct: 741 RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
Score = 34.3 bits (77), Expect = 0.79
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 1172 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1230
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 1231 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1263
L + + +Q E + KK+++Q++
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
Score = 32.3 bits (72), Expect = 3.0
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 828 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 884
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
Query: 885 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 938
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
Query: 939 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 981
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 116 bits (291), Expect = 1e-25
Identities = 93/295 (31%), Positives = 159/295 (53%), Gaps = 36/295 (12%)
Query: 746 EEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 804
E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ + + + +EE
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQARERVEQMKEE 594
Query: 805 EERQ------QQEEALRRLEERRREEEERRKQE--------ELLRKQEEEA--AKWAREE 848
+++Q Q +E + +E R EE+ +K+ E RKQEEEA +W ++E
Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654
Query: 849 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ-QQ 907
EE +R E + + EEE RLR E ++ E Q ++E R+ Q+++E RR Q+ ++
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714
Query: 908 QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLRE-EQRRQQREL 965
Q++QLA+ Q+ + QA L E +K L ++E+ RE E+++++ E
Sbjct: 715 QERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 764
Query: 966 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020
+ ++Q Q++Q+K + +G +K+L ++ Q Q H+ P
Sbjct: 765 QRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAP 814
Score = 114 bits (284), Expect = 8e-25
Identities = 83/261 (31%), Positives = 147/261 (56%), Gaps = 33/261 (12%)
Query: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR--QQEEILRRQQEEERKRR 774
LE L++ E+A+ +L +++ E + R + EE + KR+E LR+ Q E + + +EE++K+
Sbjct: 542 LENLRRKEEAE--QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 599
Query: 775 EE------EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 828
E+ E+ + K+E + +++ A ++ E E R++QEE RRL ++EEEERR
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
Query: 829 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE-EEERKRKELEVQRQK 887
QE L +K+EE E+ RLR EA RL + E+ER+ +E Q ++
Sbjct: 660 HQELLQKKKEE----------------EQERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 888 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ-SQATLSLAEIQKL 946
E R+ Q+++E R+L +Q+++++ Q +L + ++ Q Q L E +K
Sbjct: 704 EQERREQERREQERQLAEQERRRE--QERLQAERELQEREKALRLQKEQLQRELEEKKKK 761
Query: 947 EEER---ERQLREEQRRQQRE 964
EE++ ERQL+EEQ ++ +E
Sbjct: 762 EEQQRLAERQLQEEQEKKAKE 782
Score = 104 bits (259), Expect = 6e-22
Identities = 71/203 (34%), Positives = 117/203 (57%), Gaps = 25/203 (12%)
Query: 716 ALEQLQQLEKAKAAKLEQ-------------ERREAEMRAKREEEERKRQE-ELRRQQEE 761
A E+++Q+++ K ++EQ E R AE +AK++ +K +E E RR+QEE
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Query: 762 ILRRQ---QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE 818
RR Q+EE +RR +E L ++K+EE R ++ E ++ E+ER++QE +
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 819 ERRREEEERRKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEEER 876
E+ R E+ERR+QE L +QE RE+E +A+R L+E + + +L+ E EE+
Sbjct: 704 EQERREQERREQERQLAEQERR-----REQERLQAERELQEREKALRLQKEQLQRELEEK 758
Query: 877 KRKELEVQRQKELMRQRQQQQEA 899
K+KE E QR E Q +Q+++A
Sbjct: 759 KKKE-EQQRLAERQLQEEQEKKA 780
Score = 100 bits (248), Expect = 1e-20
Identities = 67/182 (36%), Positives = 111/182 (60%), Gaps = 14/182 (7%)
Query: 708 LDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERK----RQEELRRQQEEIL 763
+D T E+L + EKAK ++ E E R K+EEE R+ +QEE R+ +E+L
Sbjct: 606 IDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 664
Query: 764 RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 823
++++EEE++R + A+R E+ + +REQE + +RE+E R+Q+ RR +ER+
Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE----RREQERQLA 720
Query: 824 EEERRKQEELLRKQEE--EAAKWAR-EEEEAQRRLEENRLRMEEE--AARLRHEEEERKR 878
E+ERR+++E L+ + E E K R ++E+ QR LEE + + E++ A R EE+E+K
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780
Query: 879 KE 880
KE
Sbjct: 781 KE 782
Score = 88.6 bits (218), Expect = 4e-17
Identities = 60/240 (25%), Positives = 136/240 (56%), Gaps = 28/240 (11%)
Query: 798 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK--WARE-----EEE 850
+ ++R+ E +++E +L ++ EE++RR+ EE+ K+EE K ARE +EE
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 594
Query: 851 AQRRLEENRLRMEEEAARLRHEE--EERKRKELEVQRQKELMRQRQQQQEA--LRRLQQQ 906
++++E+ +++E+ + + E EE+ +K+ ++ +E+ +R+Q++EA LR LQQ+
Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654
Query: 907 QQQ---QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 963
+++ Q+L Q K + + AE ++L E+RE++ RE++RR+Q
Sbjct: 655 EEERRHQELLQKKKEE-------------EQERLRKAAEAKRLAEQREQERREQERREQE 701
Query: 964 ELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ-EEARQMQKQQQQQQQHQQPNR 1022
+ ++Q++++Q++ + ++ E+Q+ E+A ++QK+Q Q++ ++ +
Sbjct: 702 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 761
Score = 81.6 bits (200), Expect = 4e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 723 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 778
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 664 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 721
Query: 779 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 838
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 722 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 776
Query: 839 EEAAKWAREEEEA 851
E+ AK A +A
Sbjct: 777 EKKAKEAAGASKA 789
Score = 38.5 bits (88), Expect = 0.042
Identities = 102/528 (19%), Positives = 191/528 (36%), Gaps = 112/528 (21%)
Query: 342 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA--SQFERKDEPKTEQT 399
PD + G +TD V S P + S S QE+ + R+ KT +
Sbjct: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346
Query: 400 EKAEEE----TRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVP----- 450
A + +E L +VP + V Q+ P + A P+ P VP
Sbjct: 347 PAASGRIICHSYLERLLNVEVPQK----VGSEQKE----PPEEAEPVAAAEPEVPENNGN 398
Query: 451 ---------------NPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAY 495
NP P ETP G + D +G + Q A + +Y
Sbjct: 399 NSWPHNDTEIANSTPNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRSY 453
Query: 496 LQD-SALDDERLAS--KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN-------- 544
Q S LD+E+ +LQ R+K S P P ++ P
Sbjct: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQR 501
Query: 545 NQEMAEWFQAGYFTMSLLVKRAC-----------DESFQPLGDIMKMWGRVPFSPGPAPP 593
NQ + A M +KR ++ Q L ++ +
Sbjct: 502 NQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEE 561
Query: 594 PHMGELDQERLTRQQELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALS 643
L++ +L R++ L + Q Q + ++ I+Q++AQ+ A++++ A
Sbjct: 562 DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE 621
Query: 644 SQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 703
+++ A +++ + + + + + + + + + + Q + +
Sbjct: 622 KAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA 681
Query: 704 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAE--------------MRAKREEEER 749
L E+ +Q E+ + + EQERRE E ++A+RE +ER
Sbjct: 682 KRLAEQREQERREQERREQ-ERREQERREQERREQERQLAEQERRREQERLQAERELQER 740
Query: 750 KR-----QEELRRQQEE---------ILRRQQEEERKRREEEELARRK 783
++ +E+L+R+ EE + RQ +EE++++ +E K
Sbjct: 741 EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788
Score = 34.3 bits (77), Expect = 0.79
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 1172 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1230
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Query: 1231 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1263
L + + +Q E + KK+++Q++
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 767
Score = 32.3 bits (72), Expect = 3.0
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 828 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 884
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
Query: 885 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 938
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
Query: 939 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 981
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1368 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1427
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1487
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1488 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1714
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1715 LIRLRAETEQGEQQRQ 1730
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2182
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2183 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2233
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2234 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2349
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2470 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2514
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2573
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLL 2601
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1454
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1574
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1405
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1406 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1461
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1462 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1520
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1521 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1580
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1581 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1640
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1756
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1757 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2245 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2297
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2355
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2356 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2530
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2531 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2578 QQRRQ 2582
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1828
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1948
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1949 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2007
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1757
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1758 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1803
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2104 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2155 AALRQKQ 2161
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1864 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQK 2181
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1677 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1725
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1782
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1783 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1860 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1915
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1916 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1965
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2073
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2074 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2120
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2121 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2179
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1971 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2027
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2082
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2376
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2377 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2434
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2435 EIQRQQS 2441
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1854 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 1913
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 1914 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 1969
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2144
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2145 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2382
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2383 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2559
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2560 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2616
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2617 ASQVAATKTL 2626
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2561 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2599
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2600 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2659
Query: 888 E 888
E
Sbjct: 2660 E 2660
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 631 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 690
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 691 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 750
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 751 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 795
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1372 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1431
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1432 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1491
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1492 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1550
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1551 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1610
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1611 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1670
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1671 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1718
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1719 LIRLRAETEQGEQQRQ 1734
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2067 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2126
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2127 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2186
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2187 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2237
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2238 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2296
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2297 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2353
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2354 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2413
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2414 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2473
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2474 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2518
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2519 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2577
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2578 QQLEQQRRQQEELLAEENQRLREQLQLL 2605
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1343 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1402
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1458
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1459 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1518
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1519 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1578
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1579 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1635
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1350 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1409
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1410 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1465
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1466 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1524
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1525 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1584
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1585 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1644
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1645 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1703
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1704 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1760
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1761 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1792
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2189 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2248
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2249 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2301
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2302 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2359
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2360 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2417
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2418 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2477
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2478 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2534
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2535 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2581
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2582 QQRRQ 2586
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1653 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1712
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1713 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1772
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1773 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1832
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1833 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1893 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1952
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1953 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2011
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2012 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2052
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1761
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1762 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1807
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1808 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1867
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1868 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1927
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1928 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1987
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1988 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2047
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2048 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2107
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2108 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2158
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2159 AALRQKQ 2165
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1868 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1924
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1925 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1984
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1985 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2044
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2045 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2104
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2105 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2164
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQK 2185
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1561 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1621 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1680
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1681 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1729
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1730 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1786
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1787 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1846
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1847 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1864 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1919
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1920 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1969
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1970 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2029
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2030 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2077
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2078 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2124
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2125 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2183
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2184 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2236
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1975 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2031
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2032 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2086
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2087 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2146
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2147 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2206
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2207 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2266
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2267 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2326
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2380
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2381 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2438
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2439 EIQRQQS 2445
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1858 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 1917
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 1918 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 1973
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 1974 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2033
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 2034 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2090
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2091 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2148
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2149 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2206
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2207 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2266
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2267 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2326
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2386
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2387 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2443
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2444 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2503
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2504 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2563
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2564 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2620
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2621 ASQVAATKTL 2630
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2505 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2564
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2565 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2603
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2604 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2663
Query: 888 E 888
E
Sbjct: 2664 E 2664
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 635 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 694
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 695 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 754
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 755 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 799
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1368 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1427
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1487
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1488 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1714
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1715 LIRLRAETEQGEQQRQ 1730
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2182
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2183 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2233
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2234 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2349
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2470 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2514
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2573
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLL 2601
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1454
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1574
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1405
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1406 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1461
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1462 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1520
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1521 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1580
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1581 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1640
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1756
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1757 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2245 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2297
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2355
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2356 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2530
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2531 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2578 QQRRQ 2582
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1828
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1948
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1949 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2007
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1757
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1758 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1803
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2104 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2155 AALRQKQ 2161
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1864 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQK 2181
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1677 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1725
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1782
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1783 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1860 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1915
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1916 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1965
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2073
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2074 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2120
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2121 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2179
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1971 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2027
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2082
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2376
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2377 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2434
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2435 EIQRQQS 2441
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1854 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 1913
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 1914 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 1969
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2144
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2145 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2382
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2383 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2559
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2560 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2616
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2617 ASQVAATKTL 2626
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2561 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2599
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2600 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2659
Query: 888 E 888
E
Sbjct: 2660 E 2660
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 631 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 690
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 691 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 750
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 751 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 795
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1336 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1395
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1396 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1455
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1456 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1514
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1515 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1574
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1575 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1634
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1635 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1682
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1683 LIRLRAETEQGEQQRQ 1698
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2031 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2090
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2091 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2150
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2151 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2201
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2202 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2260
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2261 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2317
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2318 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2377
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2378 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2437
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2438 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2482
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2483 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2541
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2542 QQLEQQRRQQEELLAEENQRLREQLQLL 2569
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1307 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1366
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1422
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1423 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1482
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1483 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1542
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1543 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1599
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1314 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1373
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1374 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1429
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1430 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1488
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1489 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1548
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1549 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1608
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1609 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1667
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1668 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1724
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1725 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1756
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2153 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2212
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2213 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2265
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2266 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2323
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2324 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2381
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2382 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2441
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2442 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2498
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2499 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2545
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2546 QQRRQ 2550
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1617 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1676
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1677 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1736
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1737 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1796
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1797 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1856
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1857 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1916
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1917 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1975
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 1976 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2016
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1725
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1726 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1771
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1772 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1831
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1832 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1891
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1892 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1951
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1952 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2011
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2012 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2071
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2072 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2122
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2123 AALRQKQ 2129
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1832 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1888
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1889 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1948
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1949 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2008
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2009 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2068
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2069 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2128
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQK 2149
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1525 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1585 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1644
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1645 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1693
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1694 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1750
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1751 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1810
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1811 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1856
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1828 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1883
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1884 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1933
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1934 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 1993
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 1994 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2041
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2042 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2088
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2089 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2147
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2148 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2200
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1939 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 1995
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 1996 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2050
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2051 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2110
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2111 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2170
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2171 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2230
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2231 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2290
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2344
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2345 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2402
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2403 EIQRQQS 2409
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1822 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 1881
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 1882 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 1937
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 1938 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 1997
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 1998 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2054
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2055 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2112
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2113 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2170
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2171 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2230
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2231 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2290
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2350
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2351 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2407
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2408 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2467
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2468 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2527
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2528 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2584
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2585 ASQVAATKTL 2594
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2469 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2528
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2529 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2567
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2568 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2627
Query: 888 E 888
E
Sbjct: 2628 E 2628
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 599 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 658
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 659 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 718
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 719 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 763
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1505 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1564
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1565 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1624
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1625 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1683
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1684 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1743
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1744 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1803
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1804 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1851
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1852 LIRLRAETEQGEQQRQ 1867
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2200 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2259
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2260 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2319
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2320 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2370
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2371 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2429
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2430 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2486
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2487 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2546
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2547 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2606
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2607 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2651
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2652 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2710
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2711 QQLEQQRRQQEELLAEENQRLREQLQLL 2738
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1535
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1591
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1592 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1651
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1652 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1711
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1712 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1768
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1483 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1542
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1543 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1598
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1599 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1657
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1658 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1717
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1718 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1777
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1778 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1836
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1837 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1893
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1894 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1925
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2322 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2381
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2382 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2434
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2435 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2492
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2493 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2550
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2551 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2610
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2611 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2667
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2668 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2714
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2715 QQRRQ 2719
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1786 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1845
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1846 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1905
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1906 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1965
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1966 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 2025
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 2026 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 2085
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 2086 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2144
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2145 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2185
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1894
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1895 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1940
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1941 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 2000
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 2001 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 2060
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 2061 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 2120
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 2121 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2180
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2181 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2240
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2241 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2291
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2292 AALRQKQ 2298
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 2001 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 2057
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 2058 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2117
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 2118 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2177
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2178 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2237
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2238 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2297
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2298 QAADAEMEKHKKFAEQTLRQK 2318
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1694 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1754 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1813
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1814 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1862
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1863 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1919
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1920 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1979
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1980 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 2025
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1997 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 2052
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 2053 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 2102
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 2103 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2162
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2163 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2210
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2211 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2257
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2258 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2316
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2317 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2369
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 2108 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2164
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2165 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2219
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2220 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2279
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2280 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2339
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2340 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2399
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2400 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2513
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2514 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2571
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2572 EIQRQQS 2578
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1991 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 2050
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 2051 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 2106
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 2107 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2166
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 2167 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2223
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2224 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2281
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2282 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2339
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2340 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2399
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2400 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2519
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2520 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2577 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2636
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2637 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2696
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2697 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2753
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2754 ASQVAATKTL 2763
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2638 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2697
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2698 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2736
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2737 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2796
Query: 888 E 888
E
Sbjct: 2797 E 2797
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 768 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 827
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 828 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 887
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 888 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 932
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1346 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1405
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1406 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1465
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1466 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1524
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1525 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1584
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1585 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1644
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1645 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1692
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1693 LIRLRAETEQGEQQRQ 1708
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2041 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2100
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2101 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2160
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2161 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2211
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2212 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2270
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2271 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2327
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2328 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2387
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2388 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2447
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2448 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2492
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2493 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2551
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2552 QQLEQQRRQQEELLAEENQRLREQLQLL 2579
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1317 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1376
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1377 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1432
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1433 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1492
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1493 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1552
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1553 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1609
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1324 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1383
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1384 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1439
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1440 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1498
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1499 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1558
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1559 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1618
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1619 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1677
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1678 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1734
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1735 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1766
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2163 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2222
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2223 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2275
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2276 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2333
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2334 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2391
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2392 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2451
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2452 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2508
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2509 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2555
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2556 QQRRQ 2560
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1627 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1686
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1687 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1746
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1747 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1806
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1807 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1866
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1867 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1926
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1927 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1985
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 1986 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2026
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1735
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1736 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1781
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1782 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1841
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1842 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1901
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1902 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1961
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1962 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2021
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2022 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2081
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2082 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2132
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2133 AALRQKQ 2139
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1842 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1898
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1899 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1958
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1959 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2018
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2019 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2078
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2079 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2138
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2139 QAADAEMEKHKKFAEQTLRQK 2159
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1535 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1595 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1654
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1655 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1703
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1704 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1760
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1761 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1820
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1821 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1866
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1838 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1893
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1894 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1943
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1944 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2003
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2004 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2051
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2052 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2098
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2099 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2157
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2158 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2210
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1949 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2005
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2006 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2060
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2061 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2120
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2121 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2180
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2181 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2240
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2241 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2300
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2354
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2355 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2412
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2413 EIQRQQS 2419
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1832 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 1891
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 1892 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 1947
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 1948 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2007
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 2008 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2064
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2065 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2122
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2123 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2180
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2181 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2240
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2241 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2300
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2360
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2361 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2417
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2418 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2477
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2478 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2537
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2538 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2594
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2595 ASQVAATKTL 2604
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2479 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2538
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2539 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2577
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2578 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2637
Query: 888 E 888
E
Sbjct: 2638 E 2638
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 609 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 668
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 669 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 728
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 729 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 773
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1354 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1413
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1414 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1473
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1474 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1532
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1533 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1592
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1593 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1652
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1653 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1700
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1701 LIRLRAETEQGEQQRQ 1716
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2049 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2108
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2109 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2168
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2169 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2219
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2220 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2278
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2279 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2335
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2336 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2395
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2396 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2455
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2456 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2500
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2501 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2559
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2560 QQLEQQRRQQEELLAEENQRLREQLQLL 2587
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1325 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1384
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1385 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1440
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1441 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1500
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1501 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1560
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1561 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1617
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1332 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1391
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1392 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1447
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1448 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1506
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1507 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1566
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1567 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1626
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1627 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1685
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1686 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1742
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1743 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1774
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2171 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2230
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2231 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2283
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2284 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2341
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2342 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2399
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2400 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2459
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2460 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2516
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2517 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2563
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2564 QQRRQ 2568
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1635 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1694
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1695 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1754
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1755 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1814
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1815 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1874
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1875 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1934
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1935 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1993
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 1994 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2034
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1743
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1744 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1789
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1790 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1849
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1850 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1909
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1910 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1969
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1970 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2029
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2030 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2089
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2090 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2140
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2141 AALRQKQ 2147
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1850 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1906
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1907 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1966
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1967 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2026
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2027 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2086
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2087 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2146
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2147 QAADAEMEKHKKFAEQTLRQK 2167
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1543 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1603 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1662
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1663 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1711
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1712 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1768
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1769 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1828
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1829 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1874
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1846 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1901
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1902 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1951
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1952 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2011
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2012 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2059
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2060 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2106
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2107 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2165
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2166 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2218
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1957 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2013
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2014 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2068
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2069 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2128
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2129 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2188
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2189 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2248
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2249 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2308
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2362
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2363 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2420
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2421 EIQRQQS 2427
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1840 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 1899
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 1900 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 1955
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 1956 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2015
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 2016 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2072
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2073 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2130
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2131 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2188
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2189 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2248
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2249 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2308
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2368
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2369 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2425
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2426 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2485
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2486 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2545
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2546 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2602
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2603 ASQVAATKTL 2612
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2487 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2546
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2547 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2585
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2586 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2645
Query: 888 E 888
E
Sbjct: 2646 E 2646
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 617 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 676
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 677 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 736
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 737 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 781
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 772
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1395 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1454
Query: 773 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 806
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1455 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1514
Query: 807 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 863
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1515 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1573
Query: 864 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 895
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1574 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1633
Query: 896 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1634 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1693
Query: 948 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1741
Query: 1003 EARQMQKQQQQQQQHQ 1018
R + +Q +QQ Q
Sbjct: 1742 LIRLRAETEQGEQQRQ 1757
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2149
Query: 778 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2150 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2209
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2210 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2260
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 950
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2261 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2319
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2320 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2376
Query: 1011 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1062
++Q Q Q+ A + A +
Sbjct: 2377 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2436
Query: 1063 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1116
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2437 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2496
Query: 1117 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1176
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2497 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2541
Query: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1236
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2542 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2600
Query: 1237 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1264
Q Q QQ A ++ + +++ +++
Sbjct: 2601 QQLEQQRRQQEELLAEENQRLREQLQLL 2628
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 753 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1366 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1425
Query: 811 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 865
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1426 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1481
Query: 866 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 916
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1482 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1541
Query: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1542 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1601
Query: 977 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1602 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1658
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 600 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1373 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1432
Query: 657 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 708
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1433 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1488
Query: 709 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 756
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1489 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1547
Query: 757 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1548 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1607
Query: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 865
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1608 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1667
Query: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 922
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1668 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1726
Query: 923 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1727 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1783
Query: 982 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1014
++K + LL + +EE+R ++ +Q+
Sbjct: 1784 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1815
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 607 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 661
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2212 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2271
Query: 662 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 721
RI +N R++ + D + ++ L + L QL
Sbjct: 2272 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2324
Query: 722 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 781
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2325 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2382
Query: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2383 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2440
Query: 842 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2441 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2500
Query: 895 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2501 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2557
Query: 955 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2558 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 1015 QQHQQ 1019
QQ +Q
Sbjct: 2605 QQRRQ 2609
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 765
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1676 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1735
Query: 766 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 796
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1736 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1795
Query: 797 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 822
A + + EEE R E++ +RLE R+R
Sbjct: 1796 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1855
Query: 823 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 870
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1856 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1915
Query: 871 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 919
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1916 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1975
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1976 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2034
Query: 980 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1019
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2035 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2075
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 601 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1784
Query: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1785 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1830
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 776
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1831 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1890
Query: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 823
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1891 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1950
Query: 824 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 853
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1951 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 2010
Query: 854 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 900
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 2011 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2070
Query: 901 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2071 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2130
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2131 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2181
Query: 1012 QQQQQHQ 1018
+Q Q
Sbjct: 2182 AALRQKQ 2188
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 771
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1891 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1947
Query: 772 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 824
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1948 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2007
Query: 825 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 874
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 2008 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2067
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2068 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2127
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2128 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2187
Query: 995 SLLEIQQEEARQMQKQQQQQQ 1015
+ + E+ ++ +Q +Q+
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQK 2208
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 717 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 765
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1584 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643
Query: 766 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 820
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1644 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1703
Query: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 872
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1704 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1752
Query: 873 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 931
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1753 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1809
Query: 932 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 983
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1810 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1869
Query: 984 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1870 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1915
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1887 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1942
Query: 658 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 717
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1943 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1992
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 759
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1993 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2052
Query: 760 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2053 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2100
Query: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2101 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2147
Query: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 929
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2148 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2206
Query: 930 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 981
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2207 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2259
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 606 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 663
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1998 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2054
Query: 664 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 715
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2055 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2109
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 767
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2110 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169
Query: 768 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 809
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2170 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2229
Query: 810 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 851
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2289
Query: 852 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 885
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2290 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 886 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 937
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2403
Query: 938 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2404 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2461
Query: 998 EIQQEEA 1004
EIQ++++
Sbjct: 2462 EIQRQQS 2468
Score = 77.0 bits (188), Expect = 1e-13
Identities = 161/790 (20%), Positives = 311/790 (39%), Gaps = 88/790 (11%)
Query: 222 LAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDD-ERGYRRVRSGSGSIDDDRDSLP 280
+A ++ E R E +RRR E + + D E ++R S S + + L
Sbjct: 1881 IALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV 1940
Query: 281 EWCLED---AEEEM----GTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEG 333
E L EEE+ +F+ + A + +++ I E R ++ E E
Sbjct: 1941 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEA 1996
Query: 334 SHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQF-ERKD 392
+ + ++ ++E E+ + + A EE + ++ + +EA + ER +
Sbjct: 1997 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2056
Query: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
+ Q + A+E + K + V +Q L Q S L L
Sbjct: 2057 QESARQLQLAQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAA 2113
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
E V A + S +E + L+Q AE+ + E+L + ++
Sbjct: 2114 RRAAEEAEEARVQAEREAAQSRRQVEEA--ERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2171
Query: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLV--------K 564
A+ A+++ D + E F Q + + Q +L + K
Sbjct: 2172 EAARRAQAE--QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2229
Query: 565 RACDESFQPLGDIMKMWGRVPFSPGP---APPPHMGELDQERLTRQQELTALYQMQHLQY 621
DE Q L R + M EL + + + E AL
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2289
Query: 622 QQFLIQQ--QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNI---IPSVTRS 676
Q+FL ++ + QV + + ++++Q+ +L L ++ + ++++ + + +V +
Sbjct: 2290 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 677 VSVPDTGSIWELQPTASQPT---VWEGGSVWDLPLDTTTPG----PALEQLQQLE-KAKA 728
+ + + Q +Q + E L T G E+ +QLE A+A
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2409
Query: 729 AKLEQERREAEMRAKREEEERKRQEELRRQQEEI----------------------LRRQ 766
+L+ E R EE+ +R R+Q EEI ++RQ
Sbjct: 2410 ERLKLRVAEMSRAQARAEEDAQR---FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR------ 816
Q + R E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++
Sbjct: 2467 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2526
Query: 817 ---LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLR 870
L+ R E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +
Sbjct: 2527 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2586
Query: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
HE EE R++ E +Q E Q+++QQE L + Q+ ++QL ++ + T
Sbjct: 2587 HEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2643
Query: 931 ACQSQATLSL 940
A Q AT +L
Sbjct: 2644 ASQVAATKTL 2653
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2528 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2587
Query: 776 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2588 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2626
Query: 835 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 887
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2627 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2686
Query: 888 E 888
E
Sbjct: 2687 E 2687
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 844 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 897
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 658 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 717
Query: 898 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 955
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 718 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 777
Query: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ L LQ Q +++Q G++S + K++++++
Sbjct: 778 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 822
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 113 bits (282), Expect = 1e-24
Identities = 101/337 (29%), Positives = 166/337 (49%), Gaps = 50/337 (14%)
Query: 700 GGSVWDLPLDTTTP-------GPA-LEQLQQLEKAKAAKLEQERREAEMRAKREEEE--- 748
G S++ L T P GP+ +EQLQ +LE R+ + + +
Sbjct: 134 GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLL 193
Query: 749 RKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ 808
+RQEE R+QEE LR Q EER R +EE L +QEE LR Q E R RE+EER
Sbjct: 194 NRRQEERLREQEERLREQ--EERLREQEERLC--EQEERLREQEE------RLREQEERL 243
Query: 809 -QQEEALRRLEERRREEEER--------RKQEELLRKQEEEAAKWAREEEEAQRRLEENR 859
+QEE LR EER E+EER R+QEE L +QEE + E + RL E
Sbjct: 244 CEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQE 303
Query: 860 LRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 919
R+ E+ RL +EE + +E + Q++L Q + +E + L+Q+++Q++ ++
Sbjct: 304 ERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL--- 360
Query: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
+ L E+++L E+ ER ++++R Q+E ++ L++ ++ ++
Sbjct: 361 ---------------ERERLLEEVEELLEQ-ERLRQQDERLWQQETLQELERLRELERML 404
Query: 980 LSGWGNVSKPSGTTKS-LLEIQQEEARQMQKQQQQQQ 1015
GW + + +S E+ E +Q +QQ ++
Sbjct: 405 ELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 441
Score = 106 bits (264), Expect = 2e-22
Identities = 93/274 (33%), Positives = 141/274 (51%), Gaps = 40/274 (14%)
Query: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----EER 771
L L + ++ + + E+ RE E R + +EE QEE R+QEE LR Q+E EER
Sbjct: 190 LSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEER 249
Query: 772 KRREEEELARRKQE--EALRRQREQEIALRRQRE-----EEERQQQEEALRRLEERRREE 824
R EE L +++ E R REQE L Q E EE ++QEE L EER RE+
Sbjct: 250 LREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQ 309
Query: 825 EERR-KQEELLRKQEE---EAAKWAREE---EEAQRRLEENRLRMEEEAARLRHEEEERK 877
EER +QEE LR+QEE E K +E EE ++ LE+ R + E+E R E ER
Sbjct: 310 EERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQE----RLLERERL 365
Query: 878 RKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
+E+E ++E +RQ+ + QQE L+ L++ ++ +++ ++ A
Sbjct: 366 LEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLEL------------GWEALYE 413
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKA 968
Q + ++L E + L+ EQ Q +EL K+
Sbjct: 414 QRAEPRSGFEELNNENKSTLQLEQ--QVKELKKS 445
Score = 99.0 bits (245), Expect = 3e-20
Identities = 74/261 (28%), Positives = 132/261 (50%), Gaps = 27/261 (10%)
Query: 766 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE 825
Q E R+E E + R+ Q E + Q ++L +R+EE ++QEE LR EER RE+E
Sbjct: 163 QDETNHLRKELESVGRQLQAEV---ENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219
Query: 826 ERR-KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
ER +QEE LR+QEE + E + RL E+ R+ E+ RL +EE + +E +
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279
Query: 885 RQKE-LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 943
Q+E L Q ++ +E RL +Q+++ + + +L ++ C+ + L
Sbjct: 280 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE---KLPGQ 336
Query: 944 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1003
++L EE E+ L +E+R++++E + ++ ++ ++ L +QE
Sbjct: 337 ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELL-------------------EQER 377
Query: 1004 ARQMQKQQQQQQQHQQPNRAR 1024
RQ ++ QQ+ Q+ R R
Sbjct: 378 LRQQDERLWQQETLQELERLR 398
Score = 47.8 bits (112), Expect = 7e-05
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 21/147 (14%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ---------E 768
EQ ++L + + EQE+ + R E E+ QE + +QE +L R++ E
Sbjct: 315 EQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLE 374
Query: 769 EERKRREEEELARRKQEEALRRQREQE-------IALRRQREE-----EERQQQEEALRR 816
+ER R+++E L +++ + L R RE E AL QR E EE + ++ +
Sbjct: 375 QERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ 434
Query: 817 LEERRREEEERRKQEELLRKQEEEAAK 843
LE++ +E ++ EE + AA+
Sbjct: 435 LEQQVKELKKSGGAEEPRGSESAAAAR 461
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 108 bits (270), Expect = 3e-23
Identities = 80/322 (24%), Positives = 158/322 (49%), Gaps = 16/322 (4%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++ ++ + K +++R R + +E ER+ E RQ+E+ RQ+E ER+ E
Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
Query: 778 ELARRKQEEALR---RQREQEIALRRQREEEERQQQE---EALRRLEERRREEEERRKQE 831
E R +Q + R RQR+ E RQ + E ++Q E + R E+ R+E ER +Q
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 832 ELLRKQEEEAAKWAREEE-------EAQRRLEENRLR-MEEEAARLRHEEEERKR-KELE 882
E K E+ ++ RE E E +R+ + +R R + + R R ++ ER+R E E
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 883 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 942
+R KE R+R + ++ RR +++++Q + + ++ + +
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
Query: 943 IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
++ E ERER+ RE QR +R+ K ++++++Q + + G ++ E ++E
Sbjct: 316 KRERERERERE-RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 1003 EARQMQKQQQQQQQHQQPNRAR 1024
R Q ++++++ + +R R
Sbjct: 375 RERDRQSAREREERERDRDRDR 396
Score = 105 bits (263), Expect = 2e-22
Identities = 78/320 (24%), Positives = 166/320 (51%), Gaps = 22/320 (6%)
Query: 714 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEE-----RKRQEELRRQQEEILRRQQE 768
G E+ +Q E+ + + Q RE + + +R E+ R R E +R +E+ RQ +
Sbjct: 51 GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD 110
Query: 769 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-EEER 827
ER R+ E+E R+K+ E R+ E+E R R+ + ++++E +ER R+ + ER
Sbjct: 111 RERDRQREKERNRQKERE---RETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER 167
Query: 828 RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 887
++Q E R++E E K +E E +R+ E+ + + R R E ER+ E E +R++
Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE-TETETERKR 226
Query: 888 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
+ R+R +Q++ R ++Q ++++ ++ + ++ + + + +
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD----------RDRDRRQ 276
Query: 948 EERERQL-REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1006
+ERERQ R+ QRR +R+ ++++Q+++++ + + E Q+E R
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336
Query: 1007 MQKQQQQQQQHQ-QPNRARN 1025
+K+++++++ Q + +R RN
Sbjct: 337 REKERERKRKRQTEMDRERN 356
Score = 104 bits (260), Expect = 5e-22
Identities = 74/324 (22%), Positives = 160/324 (49%), Gaps = 26/324 (8%)
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
++ E+ + A+ E+ER+ R ++ E R+++ E + ++E R+++ E++ + E+ +
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
Query: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-----EEERRKQEELLR 835
R +E R+ E E +RQ + E +Q++ R ++ RE E ER K+ E R
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 836 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-----KELEVQRQKELM 890
++ + + +E E R + R + E R R + ER+R ++ E +R++E
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 891 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 950
R+RQ++ E R ++++++++ +M + G++ A + ++ E ER
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE---------RERERER 377
Query: 951 ERQLREEQRRQQRELMKALQQQQQQQQQK-LSGWGNVSKPSGTTKSL-LEIQQEEARQMQ 1008
+RQ E+ ++R+ + Q+++++Q +K G K K E +E R+ +
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 1009 KQQ-----QQQQQHQQPNRARNNT 1027
KQ+ +++Q +Q R R +
Sbjct: 438 KQKGRERDRERQTDRQAGRQRKRS 461
Score = 100 bits (249), Expect = 9e-21
Identities = 69/325 (21%), Positives = 155/325 (47%), Gaps = 15/325 (4%)
Query: 701 GSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR 757
G++W +PLD + P + E + L Q ++A+ ++ ER RQ+E R
Sbjct: 14 GTLWVEVTIPLDFSRRRPGSQ-----ESPRRRGLGQAHKDAD----GDDRERNRQKERER 64
Query: 758 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 817
++E+ ++ + ++ R E+ RK++ RQR++E RQ + E +Q+E+ R
Sbjct: 65 RREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQ 124
Query: 818 EERRREEE---ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 874
+ER RE E ER + + ++E E + A +E E Q E R E+
Sbjct: 125 KERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN 184
Query: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
++R+E E QR+KE + + + R ++++ + + + + Q+ +
Sbjct: 185 RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
Query: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
QA A ++ E ++ER+ ++ R + K ++Q +++Q+ + ++ +
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 995 SLLEIQQEEARQMQKQQQQQQQHQQ 1019
E ++E R+ +++++++++ ++
Sbjct: 305 RERERERERNRKRERERERERERER 329
Score = 93.2 bits (230), Expect = 1e-18
Identities = 63/264 (23%), Positives = 124/264 (46%), Gaps = 22/264 (8%)
Query: 732 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ 791
+++R+ R K+ E ER + E R +E R ++ +R RR++E + ++ R +
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 792 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 851
R++E +R+R+ E +++E +R ER RE E R++E +++E K R+ E
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 852 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 911
+ R + +A R R E ER R+ + ++E R R +Q+E R+ ++ + Q+
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 912 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 971
+++ + ++ E RER RE ++++ RE + Q
Sbjct: 413 ---------------------ETEKQREREKDRESERGRERG-REREKQKGRERDRERQT 450
Query: 972 QQQQQQQKLSGWGNVSKPSGTTKS 995
+Q +Q+ V+ P T +S
Sbjct: 451 DRQAGRQRKRSTLYVNPPPRTARS 474
Score = 87.8 bits (216), Expect = 6e-17
Identities = 67/219 (30%), Positives = 118/219 (53%), Gaps = 20/219 (9%)
Query: 718 EQLQQLEKAKAAKLEQER-------REAEMRAKREEEERKRQEELRRQQEEILRRQQEEE 770
E+ +Q E+ +A++ E ER R+ + R ++ER+RQ + +RQ+ R+ E +
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
Query: 771 RKRREEEELAR-----RKQEEALRRQREQEIALRRQREEE-ERQQQEEALRRLEERRREE 824
R+R+ E E R R++E R+RE++ R RE+E ER+++ + E R+
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 825 EERRKQEELLRKQEEEAAKW-AREEEEAQR-----RLEENRLRMEEEAARLRHEEEERKR 878
E R+Q E R++E E + ARE EE +R R +E + E++ R E++R+R
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
Query: 879 -KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916
K+ E +R +E R+R++Q+ R ++Q +Q Q K
Sbjct: 421 EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 76.3 bits (186), Expect = 2e-13
Identities = 63/227 (27%), Positives = 102/227 (44%), Gaps = 23/227 (10%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR----QQEEILRRQQEEERKR 773
E ++ E+ + + E+ER R + E ER+RQ E R ++E +RQ E +R+R
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
Query: 774 -REEEELARRKQEEALRRQREQEIALRRQREEEE----RQQQEEALRRLEERRREEEERR 828
R+ RR+ E R+RE++ R+REE E R +Q+E R+ E+ R + E
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
Query: 829 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 888
KQ E + +E E + E E Q+ E +R R + R +RKR L V
Sbjct: 416 KQREREKDRESERGRERGREREKQKGRERDRERQTD-----RQAGRQRKRSTLYVNPPPR 470
Query: 889 LMRQRQQQQEALR-----RLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
R Q + R R + + + A + P WG+ + +
Sbjct: 471 TARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFP----WGRPAKAS 513
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/258 (21%), Positives = 94/258 (36%), Gaps = 35/258 (13%)
Query: 153 REMHRSQSWEERGDRRFEKPGRKDVGRPN-FEEGGPTSVGRKHEFIRSESENWRIFREEQ 211
RE R + + DR+ EK + R E G R+ + R E E R +E+
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR-ERERQRDAEKER 159
Query: 212 NGEDEDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGS 271
+ + R R ER R + R ER+R E DR ERG R R
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 272 IDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDS 331
+ +R K E++ + E E+ ++
Sbjct: 220 TETER-------------------------------KRQTDRERDRQRKTEREREKQAER 248
Query: 332 EGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERK 391
E + +E E DK ++E ++ DR +E + + + T D +++ + +R+
Sbjct: 249 ERA-SERETERDKERERERDR-DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Query: 392 DEPKTEQTEKAEEETRME 409
E + E+ K E E E
Sbjct: 307 RERERERNRKRERERERE 324
Score = 33.9 bits (76), Expect = 1.0
Identities = 44/200 (22%), Positives = 75/200 (37%), Gaps = 19/200 (9%)
Query: 211 QNGEDEDGGWRLAGSRRDGERWRPHSPGWRE-HMERRRRFEFD-FRDRDDERGYRRVRSG 268
Q +D DG R +++ ER R RE +R RR E D R RD R +R R
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK 103
Query: 269 SGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEEC 328
DR+ D + E K+ ++E E + R D E
Sbjct: 104 ERERQTDRE-------RDRQREKERNRQ-------KERERETEREGERGRDRQTDGQRER 149
Query: 329 SDSEGSHNEEAKEPDKTNKKEGEKT---DRVGVEASEETPQTSSSSARPGTPSDHQSQEA 385
+ E ++ D+ +++ E+ +R + +E + + D S+
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 386 SQFERKDEPKTEQTEKAEEE 405
+ ER+ E +TE K + +
Sbjct: 210 RERERERETETETERKRQTD 229
Score = 33.9 bits (76), Expect = 1.0
Identities = 73/346 (21%), Positives = 115/346 (33%), Gaps = 26/346 (7%)
Query: 115 GAPRGRSSSRGRGRGRGECGFYQRSFD-EVEGVFGRGGGREMHRSQSWEERGDRRFEKPG 173
G R R R R R +R D E + R +E R ++ +ER +R ++
Sbjct: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE- 196
Query: 174 RKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWR 233
+ N E + GR+ E R R+ Q + D R + R+ E+
Sbjct: 197 -----KENKTEDRHSERGRERE--RERETETETERKRQTDRERD---RQRKTEREREKQA 246
Query: 234 PHSPGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGT 293
ER + E + RDRD +R RR + D R E E +
Sbjct: 247 ERERASERETERDKERERE-RDRDRDRD-RRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 294 FDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKT 353
+ +K ++E E + R + E + E + + + N++ G +
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDRE-KERERKRKRQTEMDRERNRQTGREG 363
Query: 354 DRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFER-----KDEPKTEQTEKAEEETRM 408
R E + SAR + Q ER KD +TEK E +
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423
Query: 409 ENSLPAKVPSR------GDEMVADVQQPLSQIPSDTASPLLILPPP 448
S + R G E + Q S L + PPP
Sbjct: 424 RESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPP 469
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 106 bits (264), Expect = 2e-22
Identities = 74/184 (40%), Positives = 109/184 (59%), Gaps = 15/184 (8%)
Query: 730 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 789
+L+QE +E +R++ QE+ R+QEE R+ E +KR E+++ RR+ EE R
Sbjct: 358 RLQQENKERSEALRRQQ---LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR 414
Query: 790 RQREQEIALRRQREEEERQQQEEALRRLEE---RRREEEERRKQEELLRKQEEEAAKWAR 846
R+RE RRQ+E E+R++++E RRLEE RR+EEEERR+ EE R+ E E R
Sbjct: 415 REREA----RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRR 470
Query: 847 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQEALRRLQQ 905
+ EE QR LE + ++ +E A L E + +E+E RQ E L RQ QQ+Q L LQ
Sbjct: 471 QLEEEQRHLEVLQQQLLQEQAMLL----ECRWREMEEHRQAERLQRQLQQEQAYLLSLQH 526
Query: 906 QQQQ 909
++
Sbjct: 527 DHRR 530
Score = 98.2 bits (243), Expect = 4e-20
Identities = 71/220 (32%), Positives = 114/220 (51%), Gaps = 26/220 (11%)
Query: 723 LEKAKAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRRQ----QEEERK 772
+++ + + E++ E E EEEE ++E + E LRR Q+E ++
Sbjct: 306 IDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE 365
Query: 773 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
R E + QE+ LR Q E + L +R++ QQ+E+ R E++RRE E RR+QE
Sbjct: 366 RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQER 425
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
R++E+E K EE E +R+ EE R R EEE R+ E+E +R+ E QR E+++Q
Sbjct: 426 EQRRREQE-EKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ 484
Query: 893 RQQQQEAL---------------RRLQQQQQQQQLAQMKL 917
+ Q++A+ RLQ+Q QQ+Q + L
Sbjct: 485 QLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSL 524
Score = 89.0 bits (219), Expect = 3e-17
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 57/305 (18%)
Query: 721 QQLEKAKAAKLEQERREAEMRAKRE-EEERKRQEELRRQQEEILRRQQEEERKRREEEE- 778
+QL K + + R+ ++ K + RK++ E + E ++EEE +E E
Sbjct: 281 EQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEP 340
Query: 779 --LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 836
+ E LRR LR Q+E +ER EALRR ++ +E++ R+QEE R+
Sbjct: 341 SSIVNVPGESTLRRD-----FLRLQQENKERS---EALRR--QQLLQEQQLREQEEYKRQ 390
Query: 837 QEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 896
E K +++E +RRLEE + R E AR + E E+R+R++ E +R +EL R+R+++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRR--EREARRQQEREQRRREQEEKRRLEELERRRKEE 448
Query: 897 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE 956
+E RR ++++++ +++ +E RQL E
Sbjct: 449 EER-RRAEEEKRR---------------------------------VEREQEYIRRQLEE 474
Query: 957 EQRRQQRELMKALQQQQQQQQQKL--SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
EQR ++ LQQQ Q+Q L W + + + ++QQE+A + Q +
Sbjct: 475 EQRH-----LEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHR 529
Query: 1015 QQHQQ 1019
+ H Q
Sbjct: 530 RPHPQ 534
Score = 87.0 bits (214), Expect = 1e-16
Identities = 50/126 (39%), Positives = 83/126 (65%), Gaps = 4/126 (3%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
++++Q ++ + EQ+RRE E R ++E E+R+R++E +R+ EE+ RR++EEE +RR EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 778 ELAR-RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 836
E R +++E +RRQ E+E +R E ++Q +E LE R RE EE R+ E L R+
Sbjct: 457 EKRRVEREQEYIRRQLEEE---QRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQ 513
Query: 837 QEEEAA 842
++E A
Sbjct: 514 LQQEQA 519
Score = 81.3 bits (199), Expect = 6e-15
Identities = 61/191 (31%), Positives = 113/191 (59%), Gaps = 21/191 (10%)
Query: 716 ALEQLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771
AL + Q L++ + + E+ +R E + R ++++E+R+R EE +R++ E RRQQE E+
Sbjct: 369 ALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA-RRQQEREQ 427
Query: 772 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 831
+RRE+EE +R+ EE RR++E+E RR+ EEE+R+ + E E RR+ EE ++
Sbjct: 428 RRREQEE--KRRLEELERRRKEEEE--RRRAEEEKRRVEREQ----EYIRRQLEEEQRHL 479
Query: 832 ELLRKQ--EEEA----AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 885
E+L++Q +E+A +W E E R+ E + ++++E A L + + +R + +
Sbjct: 480 EVLQQQLLQEQAMLLECRW--REMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQ 537
Query: 886 QKELMRQRQQQ 896
Q +Q + +
Sbjct: 538 QPPPPQQERSK 548
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 105 bits (263), Expect = 2e-22
Identities = 76/307 (24%), Positives = 168/307 (54%), Gaps = 54/307 (17%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEER-----KRQEELRRQQEEILRRQQEEERK 772
+QL QL++ K + + + E++ ++++ + Q+ L++QQE++ +Q +E++
Sbjct: 128 QQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQV 187
Query: 773 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
+++E+L ++ QE+ L +Q+++++ ++++ QQ+E L++ + ++++E+ +++Q+
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQL------QQQQLLQQQEQLQQQQFQQQQEQLQQQQQL 241
Query: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
LL +Q+ + + ++++AQ + +L +++ + +++L +Q+Q++L Q
Sbjct: 242 LLLQQQGQLQQQLLQQQQAQLQ------------QQLLEQQQAQLQQQLLLQQQEQL--Q 287
Query: 893 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERER 952
+QQQQ+ L++ Q+Q QQQQL L + + L L + E+
Sbjct: 288 QQQQQQLLQQQQEQLQQQQLQPPPLEPEE-----------EEEVELELMPVDLGSEQELE 336
Query: 953 QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQ 1012
Q R+E RQQ L++QQ+Q+Q +L K E+QQ E + Q+QQQ
Sbjct: 337 QQRQELERQQE-----LERQQEQRQLQL-------------KLQEELQQLEQQLEQQQQQ 378
Query: 1013 QQQQHQQ 1019
+QQ Q
Sbjct: 379 LEQQEVQ 385
Score = 105 bits (262), Expect = 3e-22
Identities = 78/328 (23%), Positives = 175/328 (53%), Gaps = 43/328 (13%)
Query: 709 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 768
+ T PG QLQQLE+ + E +++ + E+L++ Q + +QQ
Sbjct: 80 EETRPGQRELQLQQLEQ-----------------QPEPQQQPQHEQLQQPQPHLELQQQP 122
Query: 769 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 828
++ +++ +L + K + ++ + E+ L Q+++ + QQ +E +RL++++ + + ++
Sbjct: 123 QQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQ-QRLQQQQEQLQTQQ 181
Query: 829 KQEELLRKQEEEAAKWAREEE---EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 885
QE+ + +Q+E+ + +E++ + Q +L++ +L ++E +L+ ++ ++++++L+ Q+
Sbjct: 182 AQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE--QLQQQQFQQQQEQLQQQQ 239
Query: 886 QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK 945
Q L++Q+ Q Q+ L + QQ Q QQQL + + Q Q Q L + Q+
Sbjct: 240 QLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ------AQLQQQLLLQQQEQLQQQQQQQ 293
Query: 946 LEEERERQLR-----------EEQRRQQRELMKA---LQQQQQQQQQKLSGWGNVSKPSG 991
L ++++ QL+ EE+ + ELM +Q+ +QQ+Q+L + +
Sbjct: 294 LLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQE 353
Query: 992 TTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019
+ L++Q+E + Q+ +QQQQQ +Q
Sbjct: 354 QRQLQLKLQEELQQLEQQLEQQQQQLEQ 381
Score = 97.8 bits (242), Expect = 6e-20
Identities = 100/414 (24%), Positives = 206/414 (49%), Gaps = 89/414 (21%)
Query: 585 PFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQ-QYAQVLAQQQKAALS 643
P P + P E+ +E Q+EL Q+Q L+ Q QQ Q+ Q+ Q L
Sbjct: 64 PQRPAVSAPVGASEIAEETRPGQREL----QLQQLEQQPEPQQQPQHEQLQQPQPHLELQ 119
Query: 644 SQQQQQLALLLQQFQTLKMR-ISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS 702
Q QQ L Q Q K + + Q + P ELQ Q
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKP---------------ELQLMHQQ-------- 156
Query: 703 VWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ--QE 760
+QLQ + + +L+Q++ + + + +E++ ++QE+L++Q ++
Sbjct: 157 ---------------QQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQ 201
Query: 761 EILRRQQEEERKRR---EEEELARRK-QEEALRRQREQEIALRRQREEEERQQQEEALRR 816
++L++QQE+ ++++ ++E+L +++ Q++ + Q++Q++ L +Q+ + ++Q ++ +
Sbjct: 202 QLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ 261
Query: 817 LEERRREEEERRKQEELLRKQEEEAAKWAREE--EEAQRRLEENRLRM------EEEAAR 868
L+++ E+++ + Q++LL +Q+E+ + +++ ++ Q +L++ +L+ EEE
Sbjct: 262 LQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVE 321
Query: 869 LR------HEEEERKRKELEVQRQKELMRQRQQQQ------EALRRLQQQ--QQQQQLAQ 914
L E+E +++ E++RQ+EL RQ++Q+Q E L++L+QQ QQQQQL Q
Sbjct: 322 LELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQ 381
Query: 915 MKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKA 968
++ Q L+ E+ ++E + +L Q Q EL+ A
Sbjct: 382 QEV-----------------QLELTPVELGAQQQEVQLELTPVQPELQLELVPA 418
Score = 95.1 bits (235), Expect = 4e-19
Identities = 85/320 (26%), Positives = 160/320 (50%), Gaps = 57/320 (17%)
Query: 709 DTTTPGPALEQLQQLEKAKAAKLEQERREAEM---RAKREEEERKRQEELRRQQEEILRR 765
DT + G + Q+ E+ + +R ++ EE R Q EL+ QQ E
Sbjct: 40 DTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLE---- 95
Query: 766 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE 825
QQ E +++ + E+L + + L++Q +Q+ QQQ L++ + + +
Sbjct: 96 QQPEPQQQPQHEQLQQPQPHLELQQQPQQD-----------GQQQLSQLQQEKHQSVHHQ 144
Query: 826 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE--ERKRKELEV 883
E + + +L+ +Q++ + +E++ Q++ E+ + + +E L+ +E+ ++ +++ +
Sbjct: 145 ELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLL 204
Query: 884 QRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941
Q+Q+E ++Q+Q QQQE L++ Q QQQQ+QL Q Q Q Q L
Sbjct: 205 QQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ-----------QQQLLLLQQQGQLQQQ 253
Query: 942 EIQKLEEERERQLREEQRRQ-QRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
+Q+ + + ++QL E+Q+ Q Q++L+ LQQQ+Q QQQ Q
Sbjct: 254 LLQQQQAQLQQQLLEQQQAQLQQQLL--LQQQEQLQQQ---------------------Q 290
Query: 1001 QEEARQMQKQQQQQQQHQQP 1020
Q++ Q Q++Q QQQQ Q P
Sbjct: 291 QQQLLQQQQEQLQQQQLQPP 310
Score = 79.7 bits (195), Expect = 2e-14
Identities = 69/284 (24%), Positives = 139/284 (48%), Gaps = 50/284 (17%)
Query: 757 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 816
+++EE R +R A EE QRE ++ Q+ E ++Q Q E L++
Sbjct: 52 QEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQ 111
Query: 817 ----LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE--EAARLR 870
LE +++ +++ ++Q L++++ ++ + E Q ++ +L+ ++ E RL+
Sbjct: 112 PQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQ 171
Query: 871 HEEEE---RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQS 927
++E+ ++ +E +V +Q+E ++Q+ Q+Q+ L++ Q+Q QQQQL Q +
Sbjct: 172 QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ----------- 220
Query: 928 NTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVS 987
++L++++ +Q +E+ ++QQ+ L+ LQQQ Q QQQ L
Sbjct: 221 ----------------EQLQQQQFQQQQEQLQQQQQLLL--LQQQGQLQQQLLQ------ 256
Query: 988 KPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1031
+ ++QQ+ Q Q Q QQQ QQ + + L
Sbjct: 257 ------QQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Score = 70.5 bits (171), Expect = 1e-11
Identities = 104/490 (21%), Positives = 198/490 (40%), Gaps = 108/490 (22%)
Query: 305 KVQKEPIPEEQEMDFRPVDEGEECSD-----SEGSHNEEAKEPDKTNKKEGEKTDRVGVE 359
+++ P E ++ + +++G D S GS ++E +EP + N V
Sbjct: 15 RMEVGPATETFVLELQCLEDGGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVG 74
Query: 360 ASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSR 419
ASE +T RPG + + Q E++ EP+ + + ++ + L +
Sbjct: 75 ASEIAEET-----RPG----QRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD 125
Query: 420 GDEMVADVQQPLSQ-IPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDD 478
G + ++ +QQ Q + P L L + L+P + +
Sbjct: 126 GQQQLSQLQQEKHQSVHHQELKPELQL----MHQQQQLQPQQV---------------QE 166
Query: 479 EEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGE 538
++ L+ ++Q + A Q E+L ++QE + + E +Q+ Q +
Sbjct: 167 QQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL----LQQQQEQLQQQQLLQQQEQ 222
Query: 539 IQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGE 598
+Q Q+ E Q ++ + G+
Sbjct: 223 LQQQQFQQQ--------------------QEQLQQQQQLLLL-------------QQQGQ 249
Query: 599 LDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQ 658
L Q+ L +QQ A Q Q L+ QQ +QQ Q+L QQQ+ QQQQQ LL QQ +
Sbjct: 250 LQQQLLQQQQ---AQLQQQLLEQQQAQLQQ---QLLLQQQE---QLQQQQQQQLLQQQQE 300
Query: 659 TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 718
L+ + +LQP +P E + +P+D + +
Sbjct: 301 QLQQQ-----------------------QLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337
Query: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEE 778
Q Q+LE+ + + +QE+R+ ++ K +EE ++ +++L +QQ+++ +Q+E + E
Sbjct: 338 QRQELERQQELERQQEQRQLQL--KLQEELQQLEQQLEQQQQQL---EQQEVQLELTPVE 392
Query: 779 LARRKQEEAL 788
L ++QE L
Sbjct: 393 LGAQQQEVQL 402
Score = 37.7 bits (86), Expect = 0.072
Identities = 19/39 (48%), Positives = 28/39 (71%), Gaps = 4/39 (10%)
Query: 1191 KQKANQQRQQQQLPQQQQQQPPQQ----PPQQPQQQDSV 1225
+Q+ QQ+QQQQL QQQQ+Q QQ PP +P++++ V
Sbjct: 282 QQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEV 320
Score = 36.6 bits (83), Expect = 0.16
Identities = 66/339 (19%), Positives = 136/339 (40%), Gaps = 33/339 (9%)
Query: 953 QLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
++ EE R QREL ++ L+QQ + QQQ +P LE+QQ Q Q+
Sbjct: 77 EIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPH------LELQQ----QPQQDG 126
Query: 1012 QQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMG 1071
QQQ Q + ++ H L + + P + T+ +
Sbjct: 127 QQQLSQLQQEKHQSVHHQELKPEL-QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ-- 183
Query: 1072 FWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQ 1131
+ + + + L + +Q + ++++E+L + Q + Q+ Q
Sbjct: 184 ----EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ--QQFQQQQEQLQQ 237
Query: 1132 WCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAK 1191
+Q L L L ++ + ++ + +A L ++ Q E+ +
Sbjct: 238 --QQQLLLLQQQGQLQQQLLQQ--QQAQLQQQLLEQQQAQL-----QQQLLLQQQEQLQQ 288
Query: 1192 QKANQ--QRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNF 1249
Q+ Q Q+QQ+QL QQQ Q PP +P ++ + + + ++ + + Q Q +Q
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348
Query: 1250 EAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIE 1288
E Q ++++ Q ++ + L + ++L E++
Sbjct: 349 ERQQ--EQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQ 385
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 104 bits (260), Expect = 5e-22
Identities = 81/327 (24%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR--- 773
LE+ + ++ + ++E+ERRE E +RE E R+R+ E R++E +++E ER+R
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350
Query: 774 ----------REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 823
R+ E R +E + R +++ + + R+ E +++E R ER RE
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410
Query: 824 EEERRKQEELLRKQEEEAAKWAREEEEA---QRRLEENRLRMEEEA--ARLRHEE--EER 876
E R++E ++ E+ K REE+E +RR E +LR +E A RL++ E E +
Sbjct: 411 REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470
Query: 877 KRKELEVQRQKELMRQRQQQQEALRR---LQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 933
K +E E + ++E R+R+ +EA R L+ + + S+ + +
Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530
Query: 934 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 993
+ E ++LEE R+R L E EL + Q+ ++++Q + + + +
Sbjct: 531 ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ------IKQEPESE 584
Query: 994 KSLLEIQQEEARQMQKQQQQQQQHQQP 1020
+ E Q++E ++ + +++++ Q+P
Sbjct: 585 EEEEEKQEKEEKREEPMEEEEEPEQKP 611
Score = 99.8 bits (247), Expect = 2e-20
Identities = 76/308 (24%), Positives = 158/308 (51%), Gaps = 20/308 (6%)
Query: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREEEEL 779
++LE+ K K E+ER+E E + E ER+R+ E R R++E R++E+E++R E E
Sbjct: 289 KKLEEEKGKK-EKERQEIEKERRERERERERERERREREREREREREREKEKERERERER 347
Query: 780 AR---RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-EEERRKQEELLR 835
R R +E R RE++ R+R + + + + + +R RE E ER ++ E R
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 407
Query: 836 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL----MR 891
++E E + E E +R ++ R R E+E + ERK +E E Q+ L +R
Sbjct: 408 EREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Query: 892 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
+R++ +E + ++++++++ + + + + + A +QK +RE
Sbjct: 468 ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSA-LQKRLRDRE 526
Query: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
+++ ++R ++RE +++ ++ +Q+L G+ + L ++QE R+ Q Q
Sbjct: 527 KEMEADERDRKRE-----KEELEEIRQRLLAEGHPDPDA----ELQRMEQEAERRRQPQI 577
Query: 1012 QQQQQHQQ 1019
+Q+ + ++
Sbjct: 578 KQEPESEE 585
Score = 96.3 bits (238), Expect = 2e-19
Identities = 91/353 (25%), Positives = 150/353 (42%), Gaps = 71/353 (20%)
Query: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR---R 774
E+ ++ EK K + E+ER R K + +R R+ + R +E R ++ R R R
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEE-ERQQQEEALRRLEERRREEEERRKQEEL 833
+ E R++E R+RE+E R+RE E ER+++++ R EE + ERRK E
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449
Query: 834 LRKQE----EEAAKW-------AREEEEAQRRLEENRLRMEEEAARLRH----------- 871
LR++E E W RE E+ R EE R M +EA RL+
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509
Query: 872 ----------------------EEEERKRK--ELEVQRQKELMRQRQQQQEALRRLQQQQ 907
+E +RKR+ ELE RQ+ L L+R++Q+
Sbjct: 510 PKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEA 569
Query: 908 QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 967
++++ Q+K S ++ E Q+ EE+RE + EE+ +Q+ +K
Sbjct: 570 ERRRQPQIKQEPESEEEEE---------------EKQEKEEKREEPMEEEEEPEQKPCLK 614
Query: 968 ALQQQQQQQQQKLSGWGNV--SKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1018
+ S GN + P + + I E + QQQ ++H+
Sbjct: 615 PTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENS----PDQQQPEEHR 663
Score = 90.1 bits (222), Expect = 1e-17
Identities = 78/332 (23%), Positives = 159/332 (47%), Gaps = 53/332 (15%)
Query: 724 EKAKAAKLEQERREAEMRA---------KREEEERKRQEELRRQQEEILRRQQEEERKRR 774
E A ++E+++R+ R K EEE+ K+++E + ++E R++E ER+R
Sbjct: 262 EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERE 321
Query: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
RR++E R+RE+E R+RE E + ++ R +R RE + R +E
Sbjct: 322 ------RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS 375
Query: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-KELEVQRQKELMRQR 893
+ ++ + +RE+ + R E E E R R E ER+R +E E +R+K+ R R
Sbjct: 376 DRNKDRSR--SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR 433
Query: 894 QQQQE---ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 950
++ +E R+L+++ ++++ A + + ++ T + +A + EEER
Sbjct: 434 EEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEA--------EREEER 485
Query: 951 ERQLREEQRRQQRELM--------------KALQQQQQQQQQKLSGWGNVSKPSGTTKSL 996
R++ +E +R + L ALQ++ + +++++ K + L
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKRE--KEEL 543
Query: 997 LEIQQ--------EEARQMQKQQQQQQQHQQP 1020
EI+Q + ++Q+ +Q+ ++ +QP
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Score = 75.5 bits (184), Expect = 3e-13
Identities = 57/315 (18%), Positives = 152/315 (48%), Gaps = 49/315 (15%)
Query: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ-------------QEEILRRQ 766
++ L + +++L +E++ +++++E+K E++ R+ +E+I +
Sbjct: 211 IEVLIREYSSELNAPSQESDSHPRKKKKEKK--EDIFRRFPVAPLIPYPLITKEDINAIE 268
Query: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE-- 824
EE+++ E+++ + + + + RQ E+ER+++E R ERR E
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328
Query: 825 ----EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 880
ER K++E R++E + + +E + R E +R R E ++ + + K
Sbjct: 329 REREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKS 388
Query: 881 LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 940
+ +R++E R+R++++E R ++++++++ + +
Sbjct: 389 RDRERERERERERERERERERERERERERERERERE------------------------ 424
Query: 941 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
++ +++R+R+ EE ++R+L + L++++ Q++L W + + T + E +
Sbjct: 425 ---REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNW-EIRERKKTREYEKEAE 480
Query: 1001 QEEARQMQKQQQQQQ 1015
+EE R+ + ++ ++
Sbjct: 481 REEERRREMAKEAKR 495
Score = 46.2 bits (108), Expect = 2e-04
Identities = 61/315 (19%), Positives = 142/315 (45%), Gaps = 60/315 (19%)
Query: 717 LEQLQQLEKAKAAKLEQERREA--EMRAKREEEE-RKRQEELRRQQEEILRRQQEEERKR 773
L LQ EK K++ + + E +AK++ R E + EE L +EE KR
Sbjct: 147 LHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEAL----DEETKR 202
Query: 774 REE------EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 827
R++ E L R E +E + R++++E++ E+ RR
Sbjct: 203 RDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKK----EDIFRRFPVAPLIPYPL 258
Query: 828 RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 887
+E++ + EE + E ++ R + ++EEE + +E++R+E+E +R++
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFR--DTHKKLEEEKGK-----KEKERQEIEKERRE 311
Query: 888 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
R+R++++E RR ++++++++ + K E
Sbjct: 312 ---RERERERERERREREREREREREREK------------------------------E 338
Query: 948 EERERQL---REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1004
+ERER+ R+ R ++R+ + ++ + + +++ S S E ++E
Sbjct: 339 KERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
Query: 1005 RQMQKQQQQQQQHQQ 1019
R+ +++++++++ ++
Sbjct: 399 RERERERERERERER 413
Score = 42.7 bits (99), Expect = 0.002
Identities = 52/211 (24%), Positives = 81/211 (38%), Gaps = 12/211 (5%)
Query: 209 EEQNGEDEDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRDRDDERGYRRVRSG 268
EE+ G+ E + RR+ ER R RE R R ++++ ER R R
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 269 SGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEEC 328
+ + DRD E D + E + + S +K + E+E + E E
Sbjct: 352 DRTKERDRDRDRERD-RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER- 409
Query: 329 SDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQE-ASQ 387
E +E ++ ++E EK + E EE R + QE
Sbjct: 410 ------EREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKN 463
Query: 388 FERKDEPKTEQTEK---AEEETRMENSLPAK 415
+E ++ KT + EK EEE R E + AK
Sbjct: 464 WEIRERKKTREYEKEAEREEERRREMAKEAK 494
Score = 40.8 bits (94), Expect = 0.008
Identities = 89/418 (21%), Positives = 138/418 (33%), Gaps = 101/418 (24%)
Query: 118 RGRSSSRGRGRGRGECGFYQRSFD---EVEGVFGRGGGREMHRSQSWEERGDRRFEKPGR 174
R RSS R + R R ++S D E E R RE R + E +R E+
Sbjct: 371 RERSSDRNKDRSRSR----EKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 175 KDVGRPNFEEGGPTSVGRKHEFIRSESE--------NWRIFREEQNGEDEDGGWRLAGSR 226
KD R E+ RK E E E NW I ++ E E
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYE---------- 476
Query: 227 RDGERWRPHSPGWREHMERRRRFEFDFRD-RDDERGYRRVRSGSGSIDDDRDSLPEWCLE 285
++ ER + +R + F D+ D RDD + YR GS R L
Sbjct: 477 KEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR------GSALQKR-------LR 523
Query: 286 DAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKT 345
D E+EM + +K +KE + E ++ R + EG D+E E+ E
Sbjct: 524 DREKEMEADERD------RKREKEELEEIRQ---RLLAEGHPDPDAELQRMEQEAE---- 570
Query: 346 NKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEE 405
+ Q +++ E + E+ EK E+E
Sbjct: 571 ------------------------------------RRRQPQIKQEPESEEEEEEKQEKE 594
Query: 406 TRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTA-------------SPLLILPPPVPNP 452
+ E + + + +P+S PS ++ SP I+ P +P
Sbjct: 595 EKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSP 654
Query: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKL 510
P +G S P +K + + + +D DD KL
Sbjct: 655 DQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKL 712
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,903,835
Number of Sequences: 37866
Number of extensions: 3201318
Number of successful extensions: 141007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1601
Number of HSP's successfully gapped in prelim test: 1499
Number of HSP's that attempted gapping in prelim test: 23236
Number of HSP's gapped (non-prelim): 37416
length of query: 1293
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1179
effective length of database: 13,930,794
effective search space: 16424406126
effective search space used: 16424406126
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.