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Search of human proteins with 156766045
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
(1320 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 2649 0.0
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 2583 0.0
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 2583 0.0
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 2564 0.0
gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens] 739 0.0
gi|148746195 trichohyalin [Homo sapiens] 157 6e-38
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 140 8e-33
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 137 5e-32
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 137 9e-32
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 135 3e-31
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 134 4e-31
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 134 6e-31
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 134 6e-31
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 134 8e-31
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 127 5e-29
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 120 9e-27
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 116 1e-25
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 114 5e-25
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 114 5e-25
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 114 5e-25
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 114 5e-25
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 114 5e-25
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 114 5e-25
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 114 5e-25
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 114 5e-25
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 113 1e-24
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 108 3e-23
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 106 2e-22
gi|221139761 zinc finger protein 853 [Homo sapiens] 105 2e-22
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 104 5e-22
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 2649 bits (6866), Expect = 0.0
Identities = 1320/1320 (100%), Positives = 1320/1320 (100%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180
Query: 181 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240
NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG
Sbjct: 181 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240
Query: 241 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 300
GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI
Sbjct: 241 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 300
Query: 301 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 360
DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE
Sbjct: 301 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 360
Query: 361 GSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDE 420
GSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDE
Sbjct: 361 GSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDE 420
Query: 421 PKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPS 480
PKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPS
Sbjct: 421 PKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPS 480
Query: 481 PTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEH 540
PTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEH
Sbjct: 481 PTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEH 540
Query: 541 RAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQP 600
RAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQP
Sbjct: 541 RAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQP 600
Query: 601 LGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQV 660
LGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQV
Sbjct: 601 LGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQV 660
Query: 661 LAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTAS 720
LAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTAS
Sbjct: 661 LAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTAS 720
Query: 721 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 780
QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE
Sbjct: 721 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 780
Query: 781 ELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA 840
ELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA
Sbjct: 781 ELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA 840
Query: 841 LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 900
LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE
Sbjct: 841 LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 900
Query: 901 EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 960
EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ
Sbjct: 901 EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 960
Query: 961 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 1020
SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT
Sbjct: 961 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 1020
Query: 1021 KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS 1080
KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS
Sbjct: 1021 KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS 1080
Query: 1081 DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE 1140
DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE
Sbjct: 1081 DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE 1140
Query: 1141 KLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLG 1200
KLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLG
Sbjct: 1141 KLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLG 1200
Query: 1201 DTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTL 1260
DTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTL
Sbjct: 1201 DTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTL 1260
Query: 1261 HSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1320
HSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
Sbjct: 1261 HSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1320
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 2583 bits (6695), Expect = 0.0
Identities = 1298/1321 (98%), Positives = 1298/1321 (98%), Gaps = 23/1321 (1%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG-- 178
Query: 181 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240
RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG
Sbjct: 179 --------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 218
Query: 241 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 300
GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI
Sbjct: 219 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 278
Query: 301 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 360
DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE
Sbjct: 279 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 338
Query: 361 GSHNEEAKEPDKTNKKEGEKTDRVGV-ASEETPQTSSSSARPGTPSDHQSQEASQFERKD 419
GSHNEEAKEPDKTNKKEGEKTDRVGV ASEETPQTSSSSARPGTPSDHQSQEASQFERKD
Sbjct: 339 GSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKD 398
Query: 420 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 479
EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP
Sbjct: 399 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 458
Query: 480 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 539
SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE
Sbjct: 459 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 518
Query: 540 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 599
HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ
Sbjct: 519 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 578
Query: 600 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 659
PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ
Sbjct: 579 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 638
Query: 660 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 719
VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA
Sbjct: 639 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 698
Query: 720 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 779
SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ
Sbjct: 699 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 758
Query: 780 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE
Sbjct: 759 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC
Sbjct: 879 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
Query: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1079
TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA
Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1058
Query: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE
Sbjct: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1118
Query: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199
EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL
Sbjct: 1119 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1178
Query: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259
GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST
Sbjct: 1179 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1238
Query: 1260 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1319
LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD
Sbjct: 1239 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1298
Query: 1320 Y 1320
Y
Sbjct: 1299 Y 1299
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 2583 bits (6695), Expect = 0.0
Identities = 1298/1321 (98%), Positives = 1298/1321 (98%), Gaps = 23/1321 (1%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG-- 178
Query: 181 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240
RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG
Sbjct: 179 --------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 218
Query: 241 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 300
GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI
Sbjct: 219 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 278
Query: 301 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 360
DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE
Sbjct: 279 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 338
Query: 361 GSHNEEAKEPDKTNKKEGEKTDRVGV-ASEETPQTSSSSARPGTPSDHQSQEASQFERKD 419
GSHNEEAKEPDKTNKKEGEKTDRVGV ASEETPQTSSSSARPGTPSDHQSQEASQFERKD
Sbjct: 339 GSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKD 398
Query: 420 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 479
EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP
Sbjct: 399 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 458
Query: 480 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 539
SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE
Sbjct: 459 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 518
Query: 540 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 599
HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ
Sbjct: 519 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 578
Query: 600 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 659
PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ
Sbjct: 579 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 638
Query: 660 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 719
VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA
Sbjct: 639 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 698
Query: 720 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 779
SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ
Sbjct: 699 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 758
Query: 780 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE
Sbjct: 759 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC
Sbjct: 879 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
Query: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1079
TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA
Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1058
Query: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE
Sbjct: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1118
Query: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199
EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL
Sbjct: 1119 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1178
Query: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259
GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST
Sbjct: 1179 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1238
Query: 1260 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1319
LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD
Sbjct: 1239 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1298
Query: 1320 Y 1320
Y
Sbjct: 1299 Y 1299
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 2564 bits (6646), Expect = 0.0
Identities = 1292/1321 (97%), Positives = 1292/1321 (97%), Gaps = 29/1321 (2%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180
SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG
Sbjct: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG-- 178
Query: 181 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240
RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG
Sbjct: 179 --------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 218
Query: 241 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 300
GWRLAGSRRDGERWRPHSP GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI
Sbjct: 219 GWRLAGSRRDGERWRPHSP------GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 272
Query: 301 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 360
DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE
Sbjct: 273 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 332
Query: 361 GSHNEEAKEPDKTNKKEGEKTDRVGV-ASEETPQTSSSSARPGTPSDHQSQEASQFERKD 419
GSHNEEAKEPDKTNKKEGEKTDRVGV ASEETPQTSSSSARPGTPSDHQSQEASQFERKD
Sbjct: 333 GSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKD 392
Query: 420 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 479
EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP
Sbjct: 393 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 452
Query: 480 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 539
SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE
Sbjct: 453 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 512
Query: 540 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 599
HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ
Sbjct: 513 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 572
Query: 600 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 659
PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ
Sbjct: 573 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 632
Query: 660 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 719
VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA
Sbjct: 633 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 692
Query: 720 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 779
SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ
Sbjct: 693 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 752
Query: 780 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE
Sbjct: 753 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE
Sbjct: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC
Sbjct: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992
Query: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1079
TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA
Sbjct: 993 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1052
Query: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE
Sbjct: 1053 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112
Query: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199
EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL
Sbjct: 1113 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1172
Query: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259
GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST
Sbjct: 1173 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1232
Query: 1260 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1319
LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD
Sbjct: 1233 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1292
Query: 1320 Y 1320
Y
Sbjct: 1293 Y 1293
>gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens]
Length = 1035
Score = 739 bits (1909), Expect = 0.0
Identities = 428/860 (49%), Positives = 532/860 (61%), Gaps = 147/860 (17%)
Query: 1 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
MAAET LNFGPEWLRALS GGS+ SPP SPA+PKYKLADYRYGREEMLAL++K+NK+P
Sbjct: 1 MAAET--LNFGPEWLRALSGGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPE 58
Query: 61 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
+L DKEF +LQ+EPL PLAL P TEEEQRNFS+SVNS AVLRL G+G G + G RGR
Sbjct: 59 ELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGR 118
Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180
S+R RGRGRG+ FYQRS +E +G FGR RE+ RSQSW++RG+RRFEK R+D
Sbjct: 119 GSTRSRGRGRGDSCFYQRSIEEGDGAFGR-SPREIQRSQSWDDRGERRFEKSARRD---- 173
Query: 181 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240
R FEEGG G + E RS+SENWR REEQ E+E+G
Sbjct: 174 ------------------GARCGFEEGG---AGPRKEHARSDSENWRSLREEQE-EEEEG 211
Query: 241 GWRL-AGSRRDGERWRPHSPD-GPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSG 298
WRL AG RRDG+RWR SPD GPRSAGWREH ERRR+FEFD R G R G G
Sbjct: 212 SWRLGAGPRRDGDRWRSASPDGGPRSAGWREHGERRRKFEFDLRGDRGGCGEEEGRGGGG 271
Query: 299 S-----------IDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDF 347
S ++D+D LPEWCL+D +EEMGTFD+SGAFL LKK KEPIPEEQE+DF
Sbjct: 272 SSHLRRCRAPEGFEEDKDGLPEWCLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQELDF 331
Query: 348 RPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDH 407
+ ++E EE S+ EE P+ P P +
Sbjct: 332 QGLEEEEEPSEG---------------------------LEEEGPEAGGKELTPLPPQEE 364
Query: 408 QSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTAS 467
+S S P+ +P+ G PL D
Sbjct: 365 KS----------------------------SSPSPLPTLG---------PLWGTNGDGDE 387
Query: 468 PLLILPPPVPNP--SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQD 525
PP + L P G PG + +D+EGLKHL+Q+AEK+VA LQD
Sbjct: 388 TAEKEPPAAEDDIRGIQLSPGVGSSAGPPG------DLEDDEGLKHLQQEAEKLVASLQD 441
Query: 526 SALDDERLASKLQ----EHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQA 581
S+L++E+ + +Q H A ++PL H A +KW+YKDPQGEIQGPF QEMAEWFQA
Sbjct: 442 SSLEEEQFTAAMQTQGLRHSAAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQA 501
Query: 582 GYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALY 641
GYF+MSLLVKR CDE FQPLG+++KMWGRVPF+PGP+PPP +G +DQERL +QQEL A
Sbjct: 502 GYFSMSLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAA 561
Query: 642 QMQHLQYQQF--LIQQQYAQVLAQQQKAALS----------SQQQQQLALLLQQFQTLK- 688
Q LQ+QQF L+ + A ++KAAL QQQQQL LQQ Q LK
Sbjct: 562 LYQQLQHQQFLQLVSSRQLPQCALREKAALGDLTPPPPPPPQQQQQQLTAFLQQLQALKP 621
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
R DQN++P+++RS+SVPD+G +W++ +AS + E S+WD+P++++T GP LEQLQ
Sbjct: 622 PRGGDQNLLPTMSRSLSVPDSGRLWDVHTSASSQSGGE-ASLWDIPINSSTQGPILEQLQ 680
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
K QERRE E+RAKREEEERKR+EE RRQQ QQEE+++R+EEEEL R
Sbjct: 681 LQHKF------QERREVELRAKREEEERKRREEKRRQQ------QQEEQKRRQEEEELFR 728
Query: 809 RK---QEEALRRQREQEIAL 825
RK Q+E L + +Q+ A+
Sbjct: 729 RKHVRQQELLLKLLQQQQAV 748
Score = 244 bits (624), Expect = 3e-64
Identities = 169/442 (38%), Positives = 231/442 (52%), Gaps = 96/442 (21%)
Query: 892 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 951
E +L+H+ +ER+ EL +R++E ++R++ +R QQQQ++Q
Sbjct: 677 EQLQLQHKFQERREVELRAKREEEERKRREE-----KRRQQQQEEQ-------------- 717
Query: 952 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG-- 1009
K +E E R + RQQ L+K LQQQQ
Sbjct: 718 --------------------KRRQEEEELFRRKHVRQQELLLKLLQQQQAVPVPPAPSSP 757
Query: 1010 ---WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSV 1066
W ++K + K+LLE+Q E RQ+ KQ ++ P RA+ H
Sbjct: 758 PPLWAGLAKQGLSMKTLLELQLEGERQLHKQPPPRE----PARAQAPNH--------RVQ 805
Query: 1067 WGSINTGPPNQWASDLVSSIWSNADTK---NSNMGFWDDAVKEVGP--RNSTNKN-KNNA 1120
G + T P NQW S+ +W D +S +G W+D K G R KN +++
Sbjct: 806 LGGLGTAPLNQWVSE-AGPLWGGPDKSGGGSSGLGLWEDTPKSGGSLVRGLGLKNSRSSP 864
Query: 1121 SLSKSVG-VSNRQ-NKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTF 1178
SLS S +S R KK EEEEKLLKL QG+ + QDGFTQWCEQMLH L+ +LDVP
Sbjct: 865 SLSDSYSHLSGRPIRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATGSLDVPMA 924
Query: 1179 VSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQP 1238
V+ LKEVESPY+VHDYIR+ LGDT EAKEFAKQFLERRAKQKA+QQRQQQQ
Sbjct: 925 VAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQ--------- 975
Query: 1239 PQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLL 1298
W ++ ++L + FQ N S + + K K++ M+ +DPS+L
Sbjct: 976 ------------EAW-LSSASLQTAFQANHS----TKLGPGEGSKAKRRALMLHSDPSIL 1018
Query: 1299 GFSVNASSERLNMGEIETLDDY 1320
G+S++ SS GEIE++DDY
Sbjct: 1019 GYSLHGSS-----GEIESVDDY 1035
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 157 bits (397), Expect = 6e-38
Identities = 97/322 (30%), Positives = 189/322 (58%), Gaps = 39/322 (12%)
Query: 746 QLQQLEKAKAAKLEQERREAEMRAKREEEE---RKRQEELRRQQEEILRRQQEEERKRRE 802
+L +L + + +Q+RRE + R +EEEE RKR+ LR+++E++ + + +R+ +E
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 803 EEELARRKQEEALRRQREQEIA----------LRRQREEEERQQQEEALRRLEERRREEE 852
EEE R+ + + LRR+R++E LRR++EEE R+QQEE RR ++ RRE++
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE--RREQQERREQQ 331
Query: 853 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 912
E R++++L R+QEE + R E+E +RR ++ R EEE + E++ R+E +++R
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 913 QKELMRQRQ-QQQEALRRLQQQQQQQQL---AQMKLPSSSTWGQQSNTTACQSQATLSLA 968
+++L R++Q ++++ LRR QQ +++QQL Q++ +Q + + Q
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ------ 445
Query: 969 EIQKLEEERERQLREEQRRQQRELMKALQQ-QQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
+++ +EER L+ E+ ++ E + QQ ++ Q++++ W L+++
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW-------------LKLE 492
Query: 1028 QEEARQMQKQQQQQQQHQQPNR 1049
+EE R+ Q++++QQ + +Q R
Sbjct: 493 EEERREQQERREQQLRREQEER 514
Score = 151 bits (382), Expect = 3e-36
Identities = 109/361 (30%), Positives = 202/361 (55%), Gaps = 66/361 (18%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI----LRRQQEEERK- 799
+QL++ ++ + + ++ERRE + R RE++E +R+++LRR+QEE LRR+QEEER+
Sbjct: 304 QQLRRKQEEERREQQEERREQQER--REQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 800 ---RREEEELARRKQ---------EEALRRQ----REQEIALRRQREEEERQQQEEALRR 843
RRE+EE R +Q E+ LRR+ REQ++ +Q E++ ++E+ LRR
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 844 LEERRREEEERR--------KQEELLRKQEEEAAKWAREEEEAQRRLEENR--------- 886
++ RRE+EE R ++E+ L++++EE W + EEE +R +E R
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 887 -------LRMEEEAAR---------LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRL 930
L++EEE R LR E+EER+ + L+ Q ++E ++QR + ++ LRR
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 931 QQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ----- 985
Q+++++Q L + + ++ Q + L +++ EE R+++L+ EQ
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQL--LKREEERRQQRLKREQEERLE 599
Query: 986 RRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
+R +RE ++ L+Q+++++Q+ + KS +QEE RQ Q +++QQ++ +
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS---EEQEERRQQQLRREQQERRE 656
Query: 1046 Q 1046
Q
Sbjct: 657 Q 657
Score = 149 bits (375), Expect = 2e-35
Identities = 99/316 (31%), Positives = 187/316 (59%), Gaps = 28/316 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--EERKRRE 802
EQL++LE+ + + QE + + R +RE++ R++QEE RR+Q+E R QQE E+++ R
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 803 EEELARRKQE---EALRRQREQEIA---LRRQREEEERQQQ---EEALRRLEERRREEEE 853
E++L R ++E + LRR++E+E LRR++EEE R+QQ E+ LRR ++ RRE++
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 854 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
RR+Q +L R+Q+ + R E++ +R E +LR E+E R ++ E++R+E ++R+
Sbjct: 396 RREQ-QLRREQQLRREQQLRREQQLRR---EQQLRREQEEER-HEQKHEQERREQRLKRE 450
Query: 914 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973
+E R +++E R +Q++++QQL + + L E ++
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLK-----------RDQEEERRERWLKLEEEERREQ 499
Query: 974 EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1033
+E RE+QLR EQ ++ + +K Q+++++ QQ+L + + + L ++EE R
Sbjct: 500 QERREQQLRREQEERREQRLKR-QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 1034 MQKQQQQQQQHQQPNR 1049
Q++++Q+ + +Q R
Sbjct: 559 EQERREQRLKREQEER 574
Score = 144 bits (362), Expect = 7e-34
Identities = 155/601 (25%), Positives = 284/601 (47%), Gaps = 83/601 (13%)
Query: 742 PALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799
PAL++ + E+ + E+E R E E R ++E+E + R+EE +Q+EE L R EE K
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR--EEREK 950
Query: 800 RREEEELARRKQEEALRRQREQEIA-----LRRQ------REEEERQQQEEALRR--LEE 846
RR +E + ++++ L+++ EQ + RRQ REEEE QQ+EE L R E+
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREK 1010
Query: 847 RRREEEER--RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 904
RRR+E ER RK++EL +QEEE + REE E +R E R EEE L+ EEE+
Sbjct: 1011 RRRQEWERQYRKKDEL--QQEEE--QLLREEREKRRLQERERQYREEE--ELQQEEEQLL 1064
Query: 905 RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+E E +R++EL RQ ++++E QQ+++QL + + +Q C+ +
Sbjct: 1065 GEERETRRRQELERQYRKEEEL------QQEEEQLLREEPEKRR---RQERERQCREEEE 1115
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ---------QQQQKLSGWGNVSK 1015
L E Q L EERE++ R+E RQ RE + Q+++Q ++Q+ + +
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 1016 PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP 1075
+ LL +QE+ RQ +++Q ++++ Q + + S + W
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS--DLKW-------- 1225
Query: 1076 NQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKK 1135
QW + +++ D K G ++ +++ + ++ L +G ++++
Sbjct: 1226 -QWEPEKENAV---RDNKVYCKGRENEQFRQL-EDSQLRDRQSQQDLQHLLGEQQERDRE 1280
Query: 1136 VE------------EEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLK 1183
E EEE+L + Q K +D +Q +Q+L T F +
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Query: 1184 E-------VESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQ 1236
E E P + R + + +E ++FLE + + Q+R+++ L ++QQ
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR-RQERERKFLKEEQQL 1399
Query: 1237 QPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPS 1296
+ ++ Q Q +D + L + Q +++ E Q ++++++K + +
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQL-----SRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 1297 L 1297
L
Sbjct: 1455 L 1455
Score = 142 bits (358), Expect = 2e-33
Identities = 101/323 (31%), Positives = 185/323 (57%), Gaps = 27/323 (8%)
Query: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK--RR 801
L + QQL + + + EQ+ R + + +EEER Q+ + ++E+ L+R+QEE R +R
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR 460
Query: 802 EEE----ELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRRLEERRREEEE 853
EEE E RRKQ+ L+R +E+E RR+R EEEER++Q+E RR ++ RRE+EE
Sbjct: 461 EEETERHEQERRKQQ--LKRDQEEE---RRERWLKLEEEERREQQE--RREQQLRREQEE 513
Query: 854 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENR---LRMEEEAARLRHEEEERKRKELEV 910
RR+Q +++EE + R E++ +R EE R L+ EEE + E+R ++E E
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Query: 911 QRQKELMRQRQQQQEALRRLQQQQQQQQLAQM---KLPSSSTWGQQSNTTACQSQATLSL 967
+R + L R+ +++Q+ L+R Q+++ +Q+L + +L Q+ + + L
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 968 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
+ ++ EE R++QLR EQ+ ++ + +K ++++++ +Q+L + + L E +
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKR-EEEEERLEQRLK---REHEEERREQELAEEE 689
Query: 1028 QEEARQMQKQQQQQQQHQQPNRA 1050
QE+AR+ K + + Q Q + A
Sbjct: 690 QEQARERIKSRIPKWQWQLESEA 712
Score = 139 bits (351), Expect = 1e-32
Identities = 102/321 (31%), Positives = 178/321 (55%), Gaps = 33/321 (10%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER----KRREE 803
QQ + + + EQE R E R KR+EEE + Q+ LR +Q+ LRR+QEE R KR EE
Sbjct: 499 QQERREQQLRREQEERR-EQRLKRQEEEERLQQRLRSEQQ--LRREQEERREQLLKREEE 555
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 863
+ L + ++E+ L+R++E+ +REEE RQQ+ L+R +E R E+ +R++ E L +
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQR---LKREQEERLEQRLKREEVERLEQ 612
Query: 864 QEEEAAKWAREEEEAQRRLEENRLRMEEEAAR----LRHEEEERKRKELEVQRQKELMRQ 919
+E + REE E +RR + L+ EE+ R LR E++ER+ + L+ + ++E + Q
Sbjct: 613 EERREQRLKREEPEEERR--QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 920 RQQQQEALRRLQQQ--QQQQQLAQMKLPSSST---WGQQSNTTACQSQATLSLAEIQKLE 974
R +++ R +Q+ +++Q+ A+ ++ S W +S A QS+ + +K E
Sbjct: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV---YSRPRKQE 727
Query: 975 EERERQLREEQRR------QQRELMKALQQQQQQQQQKLSGW---GNVSKPSGTTKSLLE 1025
+R RQ +EE+RR Q +E +A +QQQ+++Q++ W G +
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Query: 1026 IQQEEARQMQKQQQQQQQHQQ 1046
E R+ Q + +++QQ +Q
Sbjct: 788 PPLREQRERQLRAEERQQREQ 808
Score = 138 bits (348), Expect = 3e-32
Identities = 103/321 (32%), Positives = 173/321 (53%), Gaps = 38/321 (11%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREE--------EERKRQEELRRQQEEILR---RQQEE 796
Q L++ + +LEQERRE ++ ++EE EE +RQ+ L+R+QEE L +++E
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Query: 797 ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ---EEALRRLEERRREEEE 853
ER +EE R K+EE +R+Q L+ + +EE RQQQ E+ RR + +REEEE
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQ--LLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 854 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
R ++ L R+ EEE + EEE ++ E + R+ + +L E + R+ K R+
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 914 KELMRQRQQQQEALRRLQQQQQQQ-------QLAQMKLPSSSTWGQQSNTTACQSQATLS 966
+E R+RQ+Q+E RR + + Q Q Q + + TW Q+ + + + LS
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 967 LAEIQKLEEERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
L E+RERQLR E+R R+QR L + +++Q+++Q++ K L
Sbjct: 786 ARP--PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR-----------EREKELQ 832
Query: 1025 EIQQEEARQMQKQQQQQQQHQ 1045
+++EE Q +++ QQ Q+ +
Sbjct: 833 FLEEEEQLQRRERAQQLQEEE 853
Score = 136 bits (342), Expect = 2e-31
Identities = 108/333 (32%), Positives = 178/333 (53%), Gaps = 36/333 (10%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEER----KRQEELRRQQEEI----LRRQQEEERK 799
+Q E+ K EQERRE R KRE+EER KR+EE R ++E L+R QEEER+
Sbjct: 428 EQEEERHEQKHEQERRE--QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 800 RR------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 853
R EE + ++E+ LRR++E+ R +R+EEE + Q+ LR ++ RRE+EE
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR-LRSEQQLRREQEE 544
Query: 854 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENR---LRMEEEAA--RLRHEEEERKRKEL 908
RR E+LL+++EE+ + R E+ +R EE R L+ EEE RL+ E+EER + L
Sbjct: 545 RR--EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Query: 909 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968
+ + + L ++ +++Q R +++++QQL +K QQ Q + L
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQL--LKSEEQEERRQQQLRREQQERREQRL- 659
Query: 969 EIQKLEEERER---QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLE 1025
K EEE ER +L+ E ++RE A ++Q+Q +++ S + K +S +
Sbjct: 660 ---KREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS---RIPKWQWQLESEAD 713
Query: 1026 IQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+Q + ++Q+ Q++ Q+ R S L
Sbjct: 714 ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Score = 133 bits (334), Expect = 1e-30
Identities = 101/322 (31%), Positives = 181/322 (56%), Gaps = 36/322 (11%)
Query: 751 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELA 807
++ + + EQER AE + E++ER Q + +R+ EE+ R++QE E +R EEE+L
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194
Query: 808 RRK--------QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER----- 854
K EE LRR+ E LRR+ EE++QQ+ E R+ + E+E R
Sbjct: 195 SCKGHETEEFPDEEQLRRRELLE--LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 855 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME-----EEAARLRHEEEERKRKEL 908
RK+EE L+++E + + +EEEE R+LE LR E ++ RLR E++ R+++E
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 909 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968
E + Q+E +R++QQE RR QQ+++++Q Q++ QQ + + L
Sbjct: 313 ERREQQE---ERREQQE--RREQQEERREQ--QLRREQEERREQQLRREQEEERREQQLR 365
Query: 969 EIQKLEEERERQLREEQR-RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
Q+ EE RE+QLR EQ+ R++++L + +QQ +++Q+L + + + +
Sbjct: 366 REQE-EERREQQLRREQQLRREQQLRR---EQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 1028 QEEARQMQKQQQQQQQHQQPNR 1049
+++ R+ Q++++ +Q+H+Q R
Sbjct: 422 EQQLRREQEEERHEQKHEQERR 443
Score = 130 bits (328), Expect = 6e-30
Identities = 124/437 (28%), Positives = 222/437 (50%), Gaps = 62/437 (14%)
Query: 626 LDQERLTRQQELTALYQMQHLQYQQ----FLIQQQYAQVLAQQQKAALSSQQ--QQQLAL 679
L++E+ R+QE ++ Q L+ Q+ FL ++Q +Q+K QQ +Q+
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 680 LLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTT 739
+Q + K R +Q + +S + + L+ + E + D
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE------ 1601
Query: 740 PGPALEQLQQLEKAKAAKLEQERR---EAEMRAKREEEERKRQEELRR--QQEEILRRQQ 794
+QL++ E + + E++R+ + ++ +REE++ RQE R+ ++E LRRQ+
Sbjct: 1602 -----QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1656
Query: 795 EEE-------RKRREEEELARRKQEEALRRQ------REQEIALRRQREEEERQQQEEAL 841
E+ RK REEE+L + +E+ LRRQ RE+E LRRQ E + Q+E+ L
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 842 RRLE-ERRREEEERRKQE---ELLRKQE-------EEAAKWAREEEEAQRR------LEE 884
RR E ER+ EEE+ +QE E LR+QE EE + REE++ +R+ EE
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Query: 885 NRLRMEEEAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943
+LR E E +LR +E +RK R+E ++++++E + R QQ++ R +++Q Q + + +
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE--LMKALQQQQQ 1001
L +Q +++ + E + EE+ Q E++RRQ+RE L + ++QQ
Sbjct: 1837 L-------RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Query: 1002 QQQQKLSGWGNVSKPSG 1018
+++Q+ G + G
Sbjct: 1890 KEEQRHRQVGEIKSQEG 1906
Score = 130 bits (327), Expect = 8e-30
Identities = 109/363 (30%), Positives = 191/363 (52%), Gaps = 52/363 (14%)
Query: 741 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKR----------QEELRRQQEEIL 790
G E+ ++ E+ K + E+E ++ E + REE E++R ++EL++++E++L
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 791 ------RRQQEEERKRREEEELARRKQE---EALRRQREQEIALRRQREEEERQQQEEAL 841
RR QE ER+ REEEEL + +++ E +R QE+ R+ R+EEE QQ+EE L
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE-RQYRKEEELQQEEEQL 1093
Query: 842 RR--LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR---- 895
R E+RRR+E ER+ +EE +QEEE + REE E +RR E R EEE +
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEE--QLLREEREKRRRQELERQYREEEEVQQEEE 1151
Query: 896 --LRHEEEERKRKELE---------VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 944
LR E E+R+R+ELE Q +++L+R+ Q+++ R Q +++++ Q +
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Query: 945 PSSSTWGQQSNTTACQSQATLSLAEIQKL-----EEERERQLREEQ---RRQQRELMKAL 996
Q+S+ + K+ E E+ RQL + Q R+ Q++L L
Sbjct: 1212 QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL 1271
Query: 997 -QQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ----HQQPNRAR 1051
+QQ++ ++Q+ W + + L +Q+EA++ ++ Q+++Q ++ R R
Sbjct: 1272 GEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Query: 1052 NNT 1054
T
Sbjct: 1332 QET 1334
Score = 127 bits (319), Expect = 7e-29
Identities = 97/325 (29%), Positives = 178/325 (54%), Gaps = 40/325 (12%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-----LRRQQEEE 797
AL Q L++ K A+ + +E+ ++ +R+EE+++R E RQ EE +++QE+E
Sbjct: 88 ALGQATGLDEEKRARCDG--KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE 145
Query: 798 RKRREEEELARRKQ--EEALRRQREQEIALRRQ--REEEERQQQEEALRRLEERRREEEE 853
R+ E EE + +++ E+ R++R++E+ +RQ +E EER+ +EE L+ + E EE
Sbjct: 146 RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSC--KGHETEE 203
Query: 854 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE-----EERKRKEL 908
+E+L R++ E + REE++ QRR ++R+ EEE R E EE K +E
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE 263
Query: 909 EVQRQKELMRQRQQ----QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT 964
E QRQ+EL + +Q +++ LRR +Q+++QQQ +++ Q+ Q +
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ-QRLRREQQLRRKQEEERREQQEERR 322
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
++ EE RE+QLR EQ ++ + ++ Q++++++QQ L
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ-----------------LR 365
Query: 1025 EIQQEEARQMQKQQQQQQQHQQPNR 1049
Q+EE R+ Q +++QQ + +Q R
Sbjct: 366 REQEEERREQQLRREQQLRREQQLR 390
Score = 125 bits (315), Expect = 2e-28
Identities = 117/581 (20%), Positives = 266/581 (45%), Gaps = 55/581 (9%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--EERKRREEEE 805
Q+L++ + +LEQE R E R KREE E +R+++L + +E+ RRQQ+ E++ R E+
Sbjct: 600 QRLKREEVERLEQEERR-EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQR 658
Query: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER------RREEEERRKQEE 859
L R ++EE L ++ ++E R+ +E ++QE+A R++ R + E E +Q +
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL----EVQRQKE 915
+ + ++ + R+E+E +RR E+ L+ +EE R ++EE +R++ + + + E
Sbjct: 719 VYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSE 778
Query: 916 LMRQRQQQQEALRRLQQQQ----QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 971
RQR + LR +++Q ++QQ Q LP Q+ + + L E +
Sbjct: 779 RGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Query: 972 K----------------LEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSK 1015
+ L+E++ER+ +EQRR Q+ + L++++++++ L + +
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQ-LEEERKRRRHTLYAKPALQE 897
Query: 1016 PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP 1075
+ LL+ ++EE ++ +++++++Q+ ++ R +
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 1076 NQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKK 1135
Q+ D K + + E + + + + + Q +
Sbjct: 958 RQYRKD------KKLQQKEEQL------LGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005
Query: 1136 VEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYI 1195
E E++ + ++ + +D Q EQ+L L ++ E+
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE-----RQYREEEELQQEE 1060
Query: 1196 RAYLGDTSEAKEFAKQFLERR-AKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWG 1254
LG+ E + +Q LER+ K++ QQ ++Q L ++ +++ Q+ +Q ++++ +
Sbjct: 1061 EQLLGEERETRR--RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 1255 MNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADP 1295
L + + + + + +++++Q ++R +P
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQ-LLREEP 1158
Score = 124 bits (311), Expect = 6e-28
Identities = 97/370 (26%), Positives = 191/370 (51%), Gaps = 83/370 (22%)
Query: 745 EQLQQLEKAKAAKLEQE---RREAEMRAKREEEERKRQEE------------------LR 783
+QL + E+ + +LE++ R+E E + +E++ +RQE L+
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 784 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE-------------QEIALRRQRE 830
++E+ L RQ+ + + EE +L R+++E+ LR R+ +E LRRQ
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 831 EEERQQQEEALRRLEERRR--EEEERRKQEELLRK-QEEEAAKWAREEEEAQRR------ 881
+ + +++E+ LRR E R+ +EE++ +++EL RK +EEE + E+E+ +R+
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 882 LEENRLRMEEEAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRR----LQQQQQQ 936
LEE +LR E E +LR +E +RK R+E ++++++E + R Q+ + R L+Q++++
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Query: 937 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR--------EEQRRQ 988
QQL + W ++ Q L E Q+L +ER+RQ R E+ RR+
Sbjct: 1810 QQLRPQQRDGKYRWEEE--------QLQLEEQE-QRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 989 QRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPN 1048
++EL + +Q+++Q++++ ++++E R+ QK++Q+ +Q +
Sbjct: 1861 EQELWQEEEQKRRQERER------------------KLREEHIRRQQKEEQRHRQVGEIK 1902
Query: 1049 RARNNTHSNL 1058
H L
Sbjct: 1903 SQEGKGHGRL 1912
Score = 123 bits (308), Expect = 1e-27
Identities = 95/324 (29%), Positives = 177/324 (54%), Gaps = 31/324 (9%)
Query: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR-QQEEILRRQQEEERKRRE 802
LE+ QQL + + K R E ++ +REE++ RQE R+ +EE R+QE +RK RE
Sbjct: 1449 LEEEQQLRQERHRKF---REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 803 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE--ERRREEEERRKQEEL 860
+E + +E R+ E+E L RQ+ + + Q+E+ LRR E ++RR++ +R+ +EE
Sbjct: 1506 QE----LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
Query: 861 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 920
+QE E + +R+E + + RLEE ++R +E+ + +E++ +R+E + Q ++E R+
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 921 QQQQEALRRLQQQQQQQQLAQMK-LPSSSTWGQQSNTTACQSQATLSLAEIQKL------ 973
++ ++ L+ ++QQ +Q K L +Q + E ++L
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
Query: 974 ----EEERERQLREEQ---RRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1026
+ER+R+ REE+ RRQ+RE K LQ++QQ ++Q+L K + E
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERE-RKFLQEEQQLRRQELE-----RKFREEEQLRQET 1735
Query: 1027 QQEEARQMQKQQQQQQQHQ-QPNR 1049
+QE+ R+ ++ ++ ++ Q +P R
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRPER 1759
Score = 121 bits (304), Expect = 4e-27
Identities = 124/479 (25%), Positives = 224/479 (46%), Gaps = 64/479 (13%)
Query: 627 DQERLTRQQELTALYQMQHLQY-QQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQ 685
++E+L R++ Q QY ++ +QQ+ Q+L ++Q+ +++Q Q Q
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 686 TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 745
K R D++ + ++ + + + + D L L+
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
Query: 746 QLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQE---------------ELRRQQEE 788
L L + + EQERR + R + EEE+ +R+E +L R++ E
Sbjct: 1269 HL--LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
Query: 789 ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER- 847
RR+QE +RK REEE+L + ++E+ LRRQ R+ EEE + QE+ + LEE
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERD-----RKFREEELRHQEQGRKFLEEEQ 1381
Query: 848 --RREEEERR--KQEELLRKQEEEAA------KWAREEEEAQRRLEENRLRMEEEAARLR 897
RR+E ER+ K+E+ LR QE E + REEE+ R E +R + EE ++R
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR-KFREEEQQVR 1440
Query: 898 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ------------QQQQLAQM--- 942
+E ERK E E Q ++E R+ +++++ L+ ++QQ ++QQL +
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 943 -KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 1001
K Q+ + + L + Q+ + E+QLR ++R QQR + + +++
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 1002 QQQQKLSGWGNVSKPSGTTKSLLEIQQ-----------EEARQMQKQQQQQQQHQQPNR 1049
+Q ++ +S+ K LE Q+ E+ +Q+++Q+ QQQ Q+ +R
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
Score = 120 bits (302), Expect = 7e-27
Identities = 102/329 (31%), Positives = 171/329 (51%), Gaps = 36/329 (10%)
Query: 745 EQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEE---LRRQQ------EEILRRQ 793
+QL+ E+ + + +++R RE E + R+E +RK +EE +RRQ+ EE + +
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456
Query: 794 QEEERKRREEEELARRKQEEALRRQR------EQEIALRRQREEEERQQQEEALRRLEER 847
QE RK REEE+L + ++E+ L RQ E+E LRRQ E +R+ +E+ LR E
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ--ERDRKFREQELRSQEPE 1514
Query: 848 RR--EEEERRKQEELLRKQEEEAAKWAREEEEAQRR-------LEENRLRMEEEAARLRH 898
R+ EEE++ +++ RK +E + R+E QRR EE +LR E E +L
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Query: 899 EEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 957
+E +RK R E + R++E R+ + ++ LRR + QQQ +Q K Q+
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 958 ACQSQ---ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVS 1014
Q E Q +ERE+QLR ++ R+ RE + LQ+ ++QQ ++
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER----D 1690
Query: 1015 KPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1043
+ + L Q+ E + +Q++QQ ++Q
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Score = 120 bits (300), Expect = 1e-26
Identities = 126/574 (21%), Positives = 253/574 (44%), Gaps = 80/574 (13%)
Query: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR----------- 792
L + QQ + + K E+E E R KRE EE +R++EL +++E R
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Query: 793 QQEEE----------RKRREEEELARRKQEEALRRQ------REQEIALRRQREEEERQ- 835
Q E E R R++E + R++QEE RR+ +E+E A R+Q+EEE+R+
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Query: 836 -----QQEE-------------ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 877
Q EE LR ER+ EER+++E+ +EEE + R+ E
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 878 AQRRL----EENRLRMEEEAARLRHEE----EERKRKELEVQRQKELMRQRQQQQEALRR 929
++ L EE +L+ E A +L+ EE E+++R+ + QR+ + R + +++ RR
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 930 --------LQQQ-QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 980
LQ+Q +++QQL Q + ++ Q + ++Q+ EE+ R+
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 981 LREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQ 1040
RE++RRQ+RE ++ QQ++++L G +P + E + E ++Q++++Q
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLG----EEPEKRRRQEREKKYREEEELQQEEEQ 1002
Query: 1041 QQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFW 1100
+ ++ R R Q L+ + +
Sbjct: 1003 LLREEREKRRRQEWERQYR-----------KKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 1101 DDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWC 1160
++ + + + + ++ + +EEE+LL+ + Q+ Q
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111
Query: 1161 EQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD--TSEAKEFAKQFLERRAK 1218
E+ L +E+E Y + ++ E ++ +Q LER+ +
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Query: 1219 QKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSV 1252
++ Q++++QL +++Q++ Q+ +Q ++++ +
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Score = 116 bits (291), Expect = 1e-25
Identities = 90/327 (27%), Positives = 184/327 (56%), Gaps = 29/327 (8%)
Query: 745 EQLQQLEKAKAAKLEQE----RREAEMRAKREEEERKRQE--ELRRQQEEILRRQQEEER 798
EQ + ++ + LE+E R++ + + +EE++ +RQE + RRQ + R++E+ R
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564
Query: 799 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE--ERRREEEERRK 856
+ REE++L+R++++ R+ R +E +RRQ +E + + E+ LRR E ++ R+E +R+
Sbjct: 1565 QEREEQQLSRQERD---RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 857 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE------EEERKRKELEV 910
+E+ QE E + R+E + + EE +LR +E +LRH+ EEE+ +E E
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
Query: 911 Q--RQKELMRQRQQQQEALRRLQQQ----QQQQQLAQMKLPSSSTWGQQSNTTACQSQAT 964
Q R++E R+ +++++ LRR +++ Q++QQL + +L +Q Q Q
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
+ LEEE+ R REEQ+ +++E + ++++Q +Q++ + + +S
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER------EEQQLRSQESDR 1795
Query: 1025 EIQQEEARQMQKQQQQQQQHQQPNRAR 1051
+ ++EE + ++++QQ + Q+ + R
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYR 1822
Score = 115 bits (287), Expect = 4e-25
Identities = 89/308 (28%), Positives = 170/308 (55%), Gaps = 20/308 (6%)
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEE---RKRQEELRRQQEEILRRQQEEERKRREE 803
L++ + + + EQ+ R R REEE+ +++LRRQ+ + + ++EE++ RR+E
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD-RKFREEEQQLRRQE 1704
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQ--QEEALRRLEERRR--EEEERR--KQ 857
E ++E+ LRRQ + R+ REEE+ +Q ++E LRR E R+ EEE+ R ++
Sbjct: 1705 RERKFLQEEQQLRRQELE----RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 858 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM 917
E+ LR+QE + + REEE+ ++ EE +LR +E + R EE+ R+ +E + R ++
Sbjct: 1761 EQQLRRQERD--RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Query: 918 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 977
+ + ++E L+ +Q+Q+ +Q + + + Q + + + L E QK +ER
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR--REEQELWQEEEQKRRQER 1876
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
ER+LREE R+Q++ + +Q + + Q+ G G + +P T + + +
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPG--THQFASVPVRSSPLYEYI 1934
Query: 1038 QQQQQQHQ 1045
Q+Q+ Q++
Sbjct: 1935 QEQRSQYR 1942
Score = 113 bits (283), Expect = 1e-24
Identities = 103/392 (26%), Positives = 180/392 (45%), Gaps = 87/392 (22%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
E++QQ E+ + ++RR E+ + EEE +QEE + +EE +R+QE ER+ REEE
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 805 ELARRKQEEALR---------------------------------------------RQR 819
EL R+K+++ R RQ
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263
Query: 820 EQEIA------LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 873
+Q++ R RE+E R+ Q+ EE + E EE+++ + RK +EE
Sbjct: 1264 QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE 1323
Query: 874 EEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQ---------KELM 917
E EE +RR EE +L E E LR +E +RK +E E++ Q ++ +
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383
Query: 918 RQRQQQQEALRRLQQ---QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
R+++++++ L+ QQ Q+++QQL Q + QQ + + ++++ E
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 975 EER-----ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
ER E+QLR+E+ R+ RE + LQ++++QQ + + LE +Q+
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR----------QERDRKFLEEEQQ 1493
Query: 1030 EARQM--QKQQQQQQQHQQPNRARNNTHSNLH 1059
RQ +K ++Q+ + Q+P R LH
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
Score = 110 bits (275), Expect = 9e-24
Identities = 89/334 (26%), Positives = 174/334 (52%), Gaps = 45/334 (13%)
Query: 759 EQERR--EAEMRAKREEEERK---RQEELRRQQEEILRRQQEEERKRREEEELAR----- 808
EQ R+ E E R +R+E ERK +++LR Q+ E RQ + + R EE++L+R
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 809 --RKQEEALRRQR------EQEIALR--------------RQREEEERQQQEEALRRLEE 846
R++E+ +RRQ E+E LR ++REE++ +QE + LEE
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 847 R---RREEEERRKQEELLRKQEEEAAKWAREEEEAQRR-------LEENRLRMEEEAARL 896
RR+E +R+ +E+ LR QE E K+ EE++ R+ EE +LR +E +
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPE-RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 897 RHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK-LPSSSTWGQQSN 955
R + + + R+E ++++++E + +Q+++ RL++Q+ ++Q + K + +Q
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 956 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSK 1015
+ + E ++L +ERE Q Q R ++ L + Q ++Q+++Q+L K
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR-HDRDRK 1668
Query: 1016 PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1049
+ L E ++++ R+ ++ ++ +++ QQ R
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Score = 44.3 bits (103), Expect = 8e-04
Identities = 65/253 (25%), Positives = 104/253 (41%), Gaps = 32/253 (12%)
Query: 201 RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDE-------DGGWRL---AGSRRD 250
R EE + R+HE R E E + EEQ E W+L A +R+
Sbjct: 661 REEEEERLEQRLKREHEEERREQE---LAEEEQEQARERIKSRIPKWQWQLESEADARQS 717
Query: 251 GERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEW 310
RP +G R +E E+RRR E + + +++ER +R+ + + RD +W
Sbjct: 718 KVYSRPRKQEGQRRR--QEQEEKRRRRESELQWQEEERAHRQQQEE----EQRRDFTWQW 771
Query: 311 CLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEP 370
E+ E S+ L ++ ++ E Q+ + R + E EE E KE
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Query: 371 DKTNKKEG-EKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKA 429
++E ++ +R EE G D Q + SQ +R+D+ Q E
Sbjct: 832 QFLEEEEQLQRRERAQQLQEE---------EDGLQED-QERRRSQEQRRDQKWRWQLE-- 879
Query: 430 EEETRMENSLPAK 442
EE R ++L AK
Sbjct: 880 EERKRRRHTLYAK 892
Score = 38.9 bits (89), Expect = 0.033
Identities = 52/230 (22%), Positives = 89/230 (38%), Gaps = 38/230 (16%)
Query: 217 EFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRR 276
+F+ E + R R +Q E+EDG + D ER R S + R WR +E
Sbjct: 832 QFLEEEEQLQRRERAQQLQEEEDG------LQEDQERRR--SQEQRRDQKWRWQLE---- 879
Query: 277 FEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQ- 335
+ER RR + ++ + L++ EEE+ + ++ Q
Sbjct: 880 ---------EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY 930
Query: 336 --KEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAK-----------EPDKTNKKEGEKTD 382
+E + +E+E R E + E + ++ K EP+K ++E EK
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 383 RVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEE 432
R EE Q R + + Q+ +KDE + E+ + EE
Sbjct: 991 R---EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Score = 31.6 bits (70), Expect = 5.3
Identities = 58/308 (18%), Positives = 115/308 (37%), Gaps = 65/308 (21%)
Query: 159 QSWEERGDRRFEKPGRKDVGKKNGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEF 218
Q W+ER +RR E+ + C+G EE R+ E
Sbjct: 178 QEWQEREERRAEEEQLQS---------------------CKGHET-EEFPDEEQLRRREL 215
Query: 219 I------RSESENWRIFREEQ-NGEDEDGGWRLAGS--RRDGERWRPHSPDGPRSAGWRE 269
+ R E + R R+++ E+E+ WR + R++ E+ + P R E
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Query: 270 HMERR-RRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAF 328
R+ R E +++E+ +R+R E L +EE
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRR-------------EQQLRRKQEEE--------- 313
Query: 329 LSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVAS 388
++ Q+E E+QE ++ EE + + +E + + +++ E+ +
Sbjct: 314 ---RREQQEERREQQERR----EQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 389 EETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGD 448
E+ + R + Q + Q R+ + + EQ + E++ R E L + R +
Sbjct: 367 EQEEERREQQLR----REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 449 EMVADVQQ 456
+ + Q+
Sbjct: 423 QQLRREQE 430
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 140 bits (353), Expect = 8e-33
Identities = 132/573 (23%), Positives = 269/573 (46%), Gaps = 60/573 (10%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----EERK 799
EQ+Q+ E+ K + E++ RE E + R+EE QE+ R+QE+ +R Q+E +ER
Sbjct: 348 EQMQEQEE-KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406
Query: 800 RREEEELARRK----QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE-R 854
R +EE + ++ Q E +R +++ + ++ R++EE+ Q+EE +R E++ REEEE
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466
Query: 855 RKQEELLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
R+QEE ++KQEE W +EE+E Q+RL E + ++ E+ +++ +EE+ +E +++ Q
Sbjct: 467 REQEEKMQKQEEN--MWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIWEQEEKIRDQ 523
Query: 914 KELMRQRQQ--QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ---SNTTACQSQATLSLA 968
+E+ Q ++ +QE +R Q+ Q +Q +M+ W Q+ T Q + T
Sbjct: 524 EEMWGQEKKMWRQEKMRE-QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE 582
Query: 969 EIQKLEE---ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1023
E + EE ERE+++REE+ R+Q E M+ +++ Q+Q++K+ W K + +
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM--WEQEEKMQEQEEKM 640
Query: 1024 LEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLV 1083
E QEE Q+++ +QQ + + H + + +
Sbjct: 641 WE--QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ---------------EQEKMQEQE 683
Query: 1084 SSIWS----NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
IW T+ WD +E + + + + + ++ K E+E
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWD---QEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199
EK+ + + + + ++ + E+M + ++E E +E + +R
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR--- 797
Query: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259
+E + E + + + + R Q++ Q+++ Q + Q++ +WG
Sbjct: 798 -----DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 1260 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVR 1292
+ + +Q Q K +++++ +R
Sbjct: 853 EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 132 bits (333), Expect = 2e-30
Identities = 106/472 (22%), Positives = 231/472 (48%), Gaps = 53/472 (11%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+E+ R +E +++ ++ +Q+Q + Q++K + +++ + ++ +T+
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466
Query: 688 -----KMRISDQNIIPSVTRSVS---VPDTGS-IWELQPTASQPT-VWEGGS-------V 730
KM+ ++N+ + +P+ +WE + Q +WE +
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526
Query: 731 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQ 786
W EQ Q+ + + +QE++ E M K +E+E+K ++ + +
Sbjct: 527 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586
Query: 787 EEILRRQQEEERKRREEEELARRKQEEALRRQRE--QEIALRRQREEEERQQQEEALRRL 844
EE R +E E+K REEEE+ R +QEE ++ Q E QE + +EE+ Q+QEE +
Sbjct: 587 EE--ERMREREKKMREEEEMMR-EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 845 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM-EEEAARLRHEEEER 903
EE+ E+EE+ +++ L +Q+E+ W E+ + Q +++E ++ E+E + +E+E+
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKL--WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 904 KRKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 960
K + E R++E MR+R++ ++E + R Q+++ Q+Q +M+ W Q+ +
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 961 S---------QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG-- 1009
+ L E +K++E+ + +EE+ R Q E M+ +++ + Q++K+ G
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 1010 ----------WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1051
WG K G + + +++ +MQ Q+++ ++ ++ R +
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Score = 127 bits (319), Expect = 7e-29
Identities = 93/314 (29%), Positives = 174/314 (55%), Gaps = 26/314 (8%)
Query: 759 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREEEELARRKQEEAL 815
E+E RE E + +++EE+ RQEE R+QE +R Q+E+ + KR E+E R+QE+ L
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 816 RRQ---REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER-RKQEELLRKQEE 866
R Q REQE ++ Q E EE+ ++QEE + R EER E+E++ R+QE+ +R QEE
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 867 ---EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 923
E + RE+EE R E+ ++E+ + +E+E+K ++ E + Q+E +R ++
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE---ERIRE 454
Query: 924 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ--SQATLSLAEIQKLEEERERQL 981
+E R +++ ++Q +M+ + W Q+ Q + L E +K++E+ E+
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 982 REEQRRQQRELM----KALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
+E++ + +E M K + +Q++ ++Q+ W K + + + QEE + + Q
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD--QEERMEKKTQ 572
Query: 1038 QQQQQQHQQPNRAR 1051
+Q+++ Q + R
Sbjct: 573 EQEKKTWDQEEKMR 586
Score = 127 bits (319), Expect = 7e-29
Identities = 107/455 (23%), Positives = 226/455 (49%), Gaps = 45/455 (9%)
Query: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
+QE R+QE Q + L+ Q+ +++Q ++ Q++ Q Q+Q + +Q +
Sbjct: 304 EQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE- 362
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS-VWDLPLDTTTPGPALE 745
KMR ++ + R E + + +WE + + E
Sbjct: 363 -KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 746 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE-- 803
Q++++ + K + EQE++ + K +EEER R+ E + ++EE R+QEE+ +++EE
Sbjct: 422 QVEKMREEKKMQ-EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 804 -EELARRKQEEALRRQREQEIALRRQREEEER-QQQEEALR-------------RLEERR 848
E+ + Q++ L Q+E+ + +E+EE+ +QEE +R R E+ R
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL------------RMEEEAARL 896
+E++ +QEE +R QE++ W +EE ++ E+ + RM E ++
Sbjct: 541 EQEDQMWEQEEKMRDQEQK--MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598
Query: 897 RHEEEERKRKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 953
R EEE + +E ++Q Q+E M+++++ +QE + Q+++ +Q +M W QQ
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 658
Query: 954 SNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ--QQQKLSGWG 1011
+ L E +K++E+ + Q +EE+ +Q ++ K Q+Q+++ Q+K+
Sbjct: 659 R-----LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 1012 NVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046
++ + + E+ +E+ +MQ+Q+++ Q+ ++
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Score = 120 bits (301), Expect = 9e-27
Identities = 108/453 (23%), Positives = 216/453 (47%), Gaps = 89/453 (19%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E Q+RL Q+E L++ + +Q Q+ I +Q ++ Q++ + +Q + Q+
Sbjct: 487 EWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Query: 685 QTL----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 740
Q KMR +Q + W+ + + T + WD
Sbjct: 545 QMWEQEEKMRDQEQKM----------------WDQEERMEKKTQEQEKKTWD-------- 580
Query: 741 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQ----QEE 796
++ + E+ + + E++ RE E + +EE+ + QEE ++QEE + Q QE+
Sbjct: 581 ----QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
Query: 797 ERKRREEEELARRKQEEALRRQR--EQEIAL---RRQREEEERQQQEEAL---RRLEERR 848
E K E+EE ++E+ +QR EQ+ L + +E+E+ Q+QEE + ++E++
Sbjct: 637 EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 849 REEE------ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 902
+E+E E+ ++EE +R++E K REEEE R EE +M+E+ +++ +EEE
Sbjct: 697 QEQEKKTWDQEKMREEESMRERE----KKMREEEEMMREQEE---KMQEQEEKMQEQEEE 749
Query: 903 RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQ 962
+E ++ Q+E M ++Q+ E +L + ++ Q+ W Q+
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-------QEKIWEQE--------- 793
Query: 963 ATLSLAEIQKLEEERERQL-REEQRRQQRELMKALQQQQQQQQQKLSG-----WGNVSKP 1016
+K+ ++ E+ +EE+ R Q E M+ +++ Q++K+ G WG K
Sbjct: 794 --------EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKM 845
Query: 1017 SGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1049
G + + E Q + +M++Q+++ + ++ R
Sbjct: 846 WGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMR 878
Score = 117 bits (292), Expect = 1e-25
Identities = 125/567 (22%), Positives = 261/567 (46%), Gaps = 94/567 (16%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREE--------EERKRQEELRRQQEEILRRQQEE 796
E ++L A++ K E + E++ K E + QEE+ RQ+EE+ +E+
Sbjct: 229 ELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL----REQ 284
Query: 797 ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK 856
E+K R++EE R++E R REQE +R Q EE+ +QE+ LR E+ RE+E+ +
Sbjct: 285 EKKIRKQEEKMWRQEE----RLREQEGKMREQ--EEKMWRQEKRLREQEKELREQEKELR 338
Query: 857 QEELLRKQEE-----EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
+++ LR+QEE E W E+EE R EE R EE RL +E++ + +E +++
Sbjct: 339 EQKELREQEEQMQEQEEKMW--EQEEKMREQEEKMWRQEE---RLWEQEKQMREQEQKMR 393
Query: 912 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQ---QSNTTACQSQATLSLA 968
Q+E M +Q E LR +++ ++Q+ W Q Q Q +
Sbjct: 394 DQEERM---WEQDERLREKEERMREQE---------KMWEQVEKMREEKKMQEQEKKTRD 441
Query: 969 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028
+ +K++EE + RE++ R++ E M+ +Q+++ Q+Q+ + W K + L Q+
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKE--WQQQRLPEQK 497
Query: 1029 EEARQMQKQQQQQQQ-HQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIW 1087
E+ + +K Q+Q+++ +Q + R+ +WG + + +W
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQ----------EEMWGQEKKMWRQEKMREQEDQMW 547
Query: 1088 SNAD-TKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLF 1146
+ ++ WD +E + + + K + + R+ +++ E EK ++
Sbjct: 548 EQEEKMRDQEQKMWDQ--EERMEKKTQEQEKKTWDQEEKM----REEERMREREKKMREE 601
Query: 1147 QGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAK 1206
+ + + Q+ Q E+ + ++ E +E + ++ E K
Sbjct: 602 EEMMREQEEKMQEQEEKMQ-----------------EQEEKMWEQEEKMQ-----EQEEK 639
Query: 1207 EFAKQFLERRAKQKANQQRQQQQLPQQQQQ----QPPQQPPQQPQQQDSVWGMNHSTLHS 1262
+ + E + ++ + +QQ+LP+Q+++ + Q+ + +Q++ +W +
Sbjct: 640 MWEQ---EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 1263 VFQTNQSNNQQSNFEAVQSGKKKKKQK 1289
Q ++ +Q+ E +++KK +
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMR 723
Score = 99.0 bits (245), Expect = 3e-20
Identities = 100/537 (18%), Positives = 233/537 (43%), Gaps = 45/537 (8%)
Query: 771 REEEERKRQEELRRQQE----EILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR 826
R ++ + EEL ++++ E+ R E +++ EL +++ L + EI L
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL---QEKLPLAESEKSEIQLN 247
Query: 827 RQREEEERQQQEEALRRLEERRREEEERRKQEEL------LRKQEEEAAKWAREE--EEA 878
+ + + ++ + L +++ +EE R++EEL +RKQEE+ W +EE E
Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK--MWRQEERLREQ 305
Query: 879 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 938
+ ++ E +M + RLR +E+E + +E E++ QKEL Q +Q QE Q+++ +Q
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE-----QEEKMWEQ 360
Query: 939 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 998
+M+ W Q+ + Q + QK+ ++ ER +++R +++E Q+
Sbjct: 361 EEKMREQEEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQE 417
Query: 999 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +Q +K+ + + T+ E QEE R +++++ +++ +
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ- 476
Query: 1059 HTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKN 1118
++W Q + +W + W+ K + K
Sbjct: 477 ----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK- 531
Query: 1119 NASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTF 1178
+ + + ++++ E+EEK+ Q + ++ + ++ T + +
Sbjct: 532 --KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE--QEKKTWDQEEKMRE 587
Query: 1179 VSFLKEVESPY-EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQ---- 1233
++E E E + +R E +E ++ E+ +Q+ Q Q++++ +Q
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 1234 -QQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQK 1289
+Q++ + + P+Q++ +W H + Q ++ +E + KK ++Q+
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLW--EHEKMQE--QEKMQEQEEKIWEQEKMEKKTQEQE 700
Score = 99.0 bits (245), Expect = 3e-20
Identities = 139/691 (20%), Positives = 283/691 (40%), Gaps = 109/691 (15%)
Query: 267 WREHMERRRRFEFDFRDRDDE--RGYRRVRSGSGSIDDDRDSL--PEWCLEDAEEEMGTF 322
WR+ E R + E R ++++ R R+R G + + + + E L + E+E+
Sbjct: 275 WRQEEELREQ-EKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333
Query: 323 DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 382
+ + QKE +E++M +E + E+ +E ++ ++ E+
Sbjct: 334 EKE------LREQKELREQEEQM--------QEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 383 RVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAK 442
E Q D + +E + R+ E EQ EK EE +M+
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQ---- 435
Query: 443 VPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTE 502
++ D ++ + + +R E +
Sbjct: 436 -----EKKTRDQEEKMQE-------------------EERIREREKKM------------ 459
Query: 503 PDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDP 562
++EE ++ E++ +K + + + E +L E + K M E +K + ++
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Query: 563 QGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPH 622
+ Q QE W Q M + ++ + KMW +
Sbjct: 519 KIRDQEEMWGQEKKMWRQE---KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 623 MGELDQE-------------RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAAL 669
DQE + R++E Q + +Q Q+ +Q+Q ++ Q++K
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM-- 633
Query: 670 SSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS 729
+Q++++ ++ + ++ +Q +P +WE + Q + E
Sbjct: 634 -QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK--------LWEHEKMQEQEKMQEQEE 684
Query: 730 -VWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEE 788
+W+ EQ ++ + + E+ RE E + + EEE + QEE ++QEE
Sbjct: 685 KIWE---QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 789 ILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 844
++ Q+EE E K E+EE + +++ L Q+E+ + +E+E+ +QEE +R
Sbjct: 742 KMQEQEEEMWEQEEKMWEQEE--KMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 845 EERRR-EEEERRKQEELLRKQEE-----EAAKWARE------EEEAQRRLEENRLRMEEE 892
EE+ R +EE+ R QEE +R QEE E W +E EE+ + E+ +M+ +
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQ 859
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQ 923
++R +EE+ + +E +++ Q+E MR ++++
Sbjct: 860 EEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 57.8 bits (138), Expect = 7e-08
Identities = 125/639 (19%), Positives = 242/639 (37%), Gaps = 120/639 (18%)
Query: 230 REEQNGEDEDGGWRLAGSRRDGER--WRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDE 287
+EEQ E E+ W R+ E WR W + + R + E RD++ E
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEE------RLWEQEKQMREQ-EQKMRDQE-E 397
Query: 288 RGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDF 347
R + + D+R L + EE M + + ++K+++E +EQE
Sbjct: 398 RMWEQ---------DER-------LREKEERMR--EQEKMWEQVEKMREEKKMQEQEKKT 439
Query: 348 RPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDH 407
R +E + + ++ +E ++T +++ EK + E + R +
Sbjct: 440 RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE- 498
Query: 408 QSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTAS 467
+ E + + ++E EQ EK ++ M K R ++M Q Q
Sbjct: 499 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQ------- 549
Query: 468 PLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSA 527
+R E + D EE ++ Q+ EK ++
Sbjct: 550 ------------EEKMRDQEQKMW------------DQEERMEKKTQEQEKKTWDQEEKM 585
Query: 528 LDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMS 587
++ER+ + ++ R + + E MQ E + QE W Q M
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQ---------EQEEKMQEQEEKMWEQEE--KMQ 634
Query: 588 LLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQ 647
++ ++ + KMW +Q+RL Q+E L++ + +Q
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMW------------------EQQRLPEQKE--KLWEHEKMQ 674
Query: 648 YQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT--------LKMRISDQNIIPS 699
Q+ + +Q+ + + +Q+K +Q+Q++ ++ + KMR ++ +
Sbjct: 675 EQEKMQEQE--EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Query: 700 VTRSVSVPDTGSIWELQPTASQPTVWEGGS-VWDLPLDTTTPGPALEQLQQLEKAKAAKL 758
+ + E + + +WE +W+ E + E+ K +
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 759 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----------EERKRREEEELA 807
E++ R+ E + + +EE+ + QEE R QEE + Q+E +E K +EE
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 808 RRKQEEALRRQREQEIALRRQRE-----EEERQQQEEAL 841
K + + REQE +R Q E EE+ + QEE +
Sbjct: 853 EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 44.7 bits (104), Expect = 6e-04
Identities = 47/246 (19%), Positives = 99/246 (40%), Gaps = 23/246 (9%)
Query: 212 VGRKHEFIRSESENW----RIFREEQNGEDEDGGWRLAGSRRDGER--W-----RPHSPD 260
+ + E IR + E W +++R+E+ E ED W RD E+ W
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Query: 261 GPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPE-----W----C 311
W + + R R++ +R + + + + E W
Sbjct: 573 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 312 LEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQE--MDFRPVDEGEECSDSEGSHNEEAKE 369
+++ EE+M + K +++ +PE++E + + E E+ + E E+ K
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 370 PDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKA 429
KT ++E + D+ + EE+ + R + +E Q E++++ + ++ E
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ-EQEEKMQEQEEEMW 751
Query: 430 EEETRM 435
E+E +M
Sbjct: 752 EQEEKM 757
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 137 bits (346), Expect = 5e-32
Identities = 113/435 (25%), Positives = 222/435 (51%), Gaps = 66/435 (15%)
Query: 630 RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 689
RL +QQE Q + +Q + IQ+Q ++ Q++K ++ ++ ++ + + KM
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 412
Query: 690 RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGSVWDLPLDTTTPGPALEQL 747
R ++ +WE + + +WE E++
Sbjct: 413 RRQEE----------------MMWEKEEKMRRQEEMMWEKE----------------EKI 440
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 807
++LE+ K+ ++ + E KR+EEE+ R++E R++QE + RQ EE+ R +EE++
Sbjct: 441 RELEE----KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKI- 493
Query: 808 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 867
R+QEE + RQ E+ + REEE+RQ+QEE R+ EE+ RE+EE +Q+E + +QEE+
Sbjct: 494 -REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKIHEQEEK 551
Query: 868 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 927
R++EE R EE +M ++ ++R +EE+ R+E +++ Q+E +R +Q+E +
Sbjct: 552 ----IRKQEEKMWRQEE---KMHDQEEKIREQEEKVWRQEEKIREQEEKIR---EQEEKI 601
Query: 928 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 987
R ++ Q+Q+ G+Q Q + E + +EE+ R+ +E++ R
Sbjct: 602 REQEEMTQEQE---------EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE-QEKKIR 651
Query: 988 QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1047
+Q E ++ ++ Q+Q++K+ W K + + E +++ RQ +K +Q+ + +Q
Sbjct: 652 EQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709
Query: 1048 NRARNNTHSNLHTSI 1062
+L +I
Sbjct: 710 EEKMQEHQEHLEAAI 724
Score = 108 bits (271), Expect = 3e-23
Identities = 85/323 (26%), Positives = 171/323 (52%), Gaps = 47/323 (14%)
Query: 628 QERLTRQQELT-----ALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQ 682
+E++ RQ+E+ + +++ ++Q I++Q + +++K ++Q+Q A + +
Sbjct: 423 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 683 QFQTLKMRISDQNIIPSVTR----SVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTT 738
Q + K+R ++ I + + + I E + Q +W
Sbjct: 482 QEE--KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR------------ 527
Query: 739 TPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--- 795
++ + E+ + + +++ E E + +++EE+ RQEE QEE +R Q+E
Sbjct: 528 ------QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Query: 796 --EERKRREEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRL 844
EE+ R +EE++ R+QEE +R Q +EQE + Q E EE+ Q+QEE +RR
Sbjct: 582 RQEEKIREQEEKI--REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 845 EERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 903
EE+ RE+E++ R+QEE +R+QEE + + E + ++ E +M+E+ ++R +EE+
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Query: 904 KRKELEVQRQKELMRQRQQQQEA 926
+E+ +++Q+E M++ Q+ EA
Sbjct: 700 WEQEVRLRQQEEKMQEHQEHLEA 722
Score = 98.2 bits (243), Expect = 5e-20
Identities = 88/345 (25%), Positives = 174/345 (50%), Gaps = 53/345 (15%)
Query: 732 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 791
+L +T T E+ +L++ K +E E+ E ++ K + + +R + L QQ+
Sbjct: 269 ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 323
Query: 792 RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 850
Q E + +E + ++ + Q + E E+ R Q++EE+ +QEE ++ EE+ +E
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379
Query: 851 EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 892
+EE+ R+QEE +R+QEE E W +EE EE RR EE EE+
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439
Query: 893 AARLRHE--EEERKRKELEVQRQKELMR--QRQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
L + E+E+ R++ E ++++E +R +++Q+QEA Q+++ ++Q +++
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 949 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQ----------RELMKALQQ 998
W Q+ + E +K+ EE +RQ +EE RQ+ R+ K +Q
Sbjct: 500 MWRQEE-----------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548
Query: 999 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1043
+++ ++Q+ W K + + E +++ RQ +K ++Q+++
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK 593
Score = 75.1 bits (183), Expect = 4e-13
Identities = 58/297 (19%), Positives = 139/297 (46%), Gaps = 23/297 (7%)
Query: 757 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 816
+L +ER + R + +E + +E L+ + E+ + + + +RK E A
Sbjct: 258 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 317
Query: 817 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR-KQEEEAAKWAREE 875
+Q++ +E Q L+ E +Q+E +QEE+ +W +
Sbjct: 318 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377
Query: 876 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ 935
+E + ++ E ++ E+ ++R +EE KE +++RQ+E+M +++E +RR ++
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM---WEKEEKMRRQEEMMW 434
Query: 936 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQR-RQQRELMK 994
+++ +L ++ + Q + E +K +E+ + R+E++ R+Q E ++
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 995 ALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1051
+++ +Q++K+ +QE+ R+ +K+Q+Q++ +Q + R
Sbjct: 495 EQEEKMWRQEEKIH------------------EQEKIREEEKRQEQEEMWRQEEKIR 533
Score = 59.3 bits (142), Expect = 2e-08
Identities = 87/500 (17%), Positives = 203/500 (40%), Gaps = 86/500 (17%)
Query: 802 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 835
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 836 --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 883
+ E+AL + ++++ EE K+ + L + E +E +L+
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 884 ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943
E +E E + ++ +E KRK ++R K L+ Q+Q Q EA ++ Q Q +
Sbjct: 289 EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 345
Query: 944 LPSSSTW---GQQSNTTACQSQATLSLAE--IQKLEE---ERERQLREEQRRQQRELMKA 995
+ + W QQ + + + E IQ+ EE E+E ++RE++ + +R+
Sbjct: 346 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405
Query: 996 LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ------QEEARQMQKQQQQQQQHQQPNR 1049
+++++ ++Q+ W K + + E + +E+ + +K ++Q+++ Q+ +
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 465
Query: 1050 ARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGP 1109
R + +W + + + M ++ + E
Sbjct: 466 IREQEKRQEQEA---KMWRQ----------EEKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Query: 1110 RNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNT 1169
K + + RQ +K+ E+E++ + + +++ ++ + E+M
Sbjct: 513 IREEEKRQEQEEMW-------RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Query: 1170 ANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1229
++ + ++ E + + IR E +E ++ E+ +Q+ Q Q+++
Sbjct: 566 MHDQE----EKIREQEEKVWRQEEKIR-------EQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 1230 LPQQQQQQPPQQPPQQPQQQ 1249
+ +Q+++ Q+ Q Q++
Sbjct: 615 MGEQEEKMCEQEEKMQEQEE 634
Score = 47.8 bits (112), Expect = 7e-05
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 61/215 (28%)
Query: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
DQE R+QE Q + ++ Q+ I++Q ++ Q++ ++ +Q++++ ++
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE---MTQEQEEKMGEQEEKMCE 624
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
+ ++ +Q E+
Sbjct: 625 QEEKMQEQE-------------------------------------------------EK 635
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806
+++ E+ K + E++ RE E + + +EE + QEE +QEE + E+E K +E+EE
Sbjct: 636 MRRQEE-KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE---KMCEQEEKMQEQEEK 691
Query: 807 ARRKQEEALRRQREQEIALRRQREE-EERQQQEEA 840
RR++E + EQE+ LR+Q E+ +E Q+ EA
Sbjct: 692 MRRQEE----KMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/410 (17%), Positives = 162/410 (39%), Gaps = 49/410 (11%)
Query: 890 EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 949
+E+ A +H+E R+ E +V + L Q+ + Q AL Q +Q + L S
Sbjct: 170 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 228
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 1002
S A + + LS QK + +R +L +E+ EL + L+++ +
Sbjct: 229 --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 286
Query: 1003 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
Q+KL + L+ + E A+ + QQQ Q + + + + L +
Sbjct: 287 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 346
Query: 1063 G-NSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1121
N +W +N + +W + W++ ++E + + K
Sbjct: 347 EENELWNRLNQQQEEK--------MWRQEEKIQE----WEEKIQEQEEKIREQEEKIREQ 394
Query: 1122 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1181
K + ++ E+EEK+ + + + + ++ + E M
Sbjct: 395 EEK---MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK------------ 439
Query: 1182 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1241
++E+E + IR E ++ +Q E+R +Q+A RQ++++ +Q++
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEE------ 491
Query: 1242 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
+ +Q++ +W +H + + +Q E + +K ++Q+ +
Sbjct: 492 --KIREQEEKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Score = 32.3 bits (72), Expect = 3.1
Identities = 50/237 (21%), Positives = 92/237 (38%), Gaps = 48/237 (20%)
Query: 212 VGRKHEFIRSESEN-WRI---------FREEQNGEDEDGGWRLAGSRRDGER-WRPHSPD 260
+ + E IR + E WR REE+ ++++ WR R+ E WR
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 261 GPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMG 320
+ R+ E+ R E D+++ ++R + + + E EE++
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEE-----KIREQEEKVWRQEEKIRE-----QEEKI- 594
Query: 321 TFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEK 380
+ Q+E I E++EM +E + G E+ E ++ +++ EK
Sbjct: 595 ------------REQEEKIREQEEMT-------QEQEEKMGEQEEKMCEQEEKMQEQEEK 635
Query: 381 TDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEK-AEEETRME 436
R EE + R + +E Q ++E EQ EK E+E +M+
Sbjct: 636 MRR----QEEKIREQEKKIREQEEKIREQEEMMQ--EQEEKMWEQEEKMCEQEEKMQ 686
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 137 bits (344), Expect = 9e-32
Identities = 90/318 (28%), Positives = 183/318 (57%), Gaps = 22/318 (6%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE---EE 804
QQ +A+A L +E + + + + EE + L +QQEE + RQ+E+ ++R E E+
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 805 ELARRKQEEALRRQREQ--EIALRRQREEEERQQQEEALRRLEERR------REEEERRK 856
E R+QEE +RRQ E E + +R+EE ++EE +R LEE+ RE+EE+R+
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 857 QEELLR----KQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 910
+EE +R +QE+EA W +EE+ E + ++ E M+E+ ++ +EE+ +E E+
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 911 QRQKELMRQRQQQ-QEALRRLQQQQQQ-QQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968
Q Q+E MR+++++ +E +++++Q+++ ++ +M G+Q C+ +A +
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG-KMCEQEAKMQEQ 486
Query: 969 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028
E + +E + + +E++ R+Q E ++ ++ Q+Q++K+ W K + + E ++
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEE 544
Query: 1029 EEARQMQKQQQQQQQHQQ 1046
+ RQ +K ++Q+ + +Q
Sbjct: 545 KMRRQEEKMREQEVRLRQ 562
Score = 125 bits (315), Expect = 2e-28
Identities = 71/276 (25%), Positives = 162/276 (58%), Gaps = 15/276 (5%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE----EERKR 800
E+ ++ K + E++ +E E + + +EE+ +RQEE+ ++EE +RRQ+E +E K
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 859
RE EE + ++E +R Q E+ + RE+E+RQ+QE + R EE+ RE+EE+ R+QEE
Sbjct: 347 RELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
++++QEE+ + + E + ++E +M + ++R +E++ + +E +++ Q+E+M++
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Query: 920 RQQQQ--------EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 971
++++ E ++Q+Q+++ + + K+ ++ + + + E +
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 972 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 1007
E+E + +EE+ ++Q E M+ +++ ++Q+ +L
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560
Score = 121 bits (304), Expect = 4e-27
Identities = 83/271 (30%), Positives = 161/271 (59%), Gaps = 47/271 (17%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
E++ ++ K +LE++ E E K E+E KRQEE + +++E +RQ++E + R+EE
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQE---KIREQEEKRQEEEKIREQE--KRQEQEAKMWRQEE 390
Query: 805 ELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER- 854
++ R+QEE +R Q +EQE + Q E EEE Q+QEE +RR EE+ RE+E++
Sbjct: 391 KI--REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 855 RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 914
R+QEE +R+QEE +E + ++ E +M E+ A+++ +EE+ +R+E +++ Q+
Sbjct: 449 REQEEKIREQEEMM-------QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 915 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
+ +R +Q+E +R ++ Q+Q+ W Q+ C+ + +K++
Sbjct: 502 KKIR---EQEEKIREQEEMMQEQE--------EKMWEQEEK--MCEQE--------EKMQ 540
Query: 975 EERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
E+ E+ R+E++ +++E+ L+QQ+++ Q+
Sbjct: 541 EQEEKMRRQEEKMREQEV--RLRQQEEKMQE 569
Score = 112 bits (279), Expect = 3e-24
Identities = 90/326 (27%), Positives = 172/326 (52%), Gaps = 20/326 (6%)
Query: 631 LTRQQELTALYQMQHLQYQ-QFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 689
L QQ+L A + HL + Q + + AQV + L+ QQ++++ ++ Q +
Sbjct: 245 LLPQQQLQA--EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302
Query: 690 RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGS-VWDLPLDTTTPGPALEQ 746
+I +Q +WE + + +WE + +L EQ
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREE 803
++ ++ + + +++R+E E + R+EE+ + QEE R+QEE+++ Q+E E+ ++ E
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422
Query: 804 EELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER 854
+E ++QEE +RRQ REQE +R Q E EE Q+QEE + E + E+E +
Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Query: 855 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
++QEE +R+QEE+ + ++ E + ++ E M+E+ ++ +EE+ +E ++Q Q
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 542
Query: 914 KELM-RQRQQQQEALRRLQQQQQQQQ 938
+E M RQ ++ +E RL+QQ+++ Q
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 85.9 bits (211), Expect = 2e-16
Identities = 80/325 (24%), Positives = 162/325 (49%), Gaps = 37/325 (11%)
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERKRREE 803
+++L K + A + R + +E+ K QE+L+ ++ EI +E +RK
Sbjct: 183 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 242
Query: 804 EELARRKQEEALRRQREQEIA-----LRRQREEEE-----RQQQEEALRRLEERRREEEE 853
+ L ++Q +A +E+ L+ Q EE E QQQEE + R EE+ +E EE
Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302
Query: 854 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE--EEERKRKELE-- 909
+ +++QEE+ RE+EE RR EE EE+ R E+E K +ELE
Sbjct: 303 K------IQEQEEKI----REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 910 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQM-----KLPSSSTWGQQSNTTACQSQAT 964
+ Q+++ Q +++QE + +Q+++Q+Q A+M K+ ++ + +
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
+ E + E+E E Q +EE+ R+Q E ++ +++ ++Q++K+ + +
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE----- 467
Query: 1025 EIQQEEARQMQKQQQQQQQHQQPNR 1049
++ ++E + +++ + Q+Q ++ R
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRR 492
Score = 61.2 bits (147), Expect = 6e-09
Identities = 64/324 (19%), Positives = 136/324 (41%), Gaps = 90/324 (27%)
Query: 802 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 835
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 836 -------------------QQEEALRRLEERRRE------------------EEERRKQE 858
Q+++A R +EE +E +E+ K +
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215
Query: 859 ELLRKQEEEAAKWAREEEEAQRRLEENRL-----RMEEEAARLRHE------------EE 901
E L+ E E ++ +E +R+LE +L +++ EA L E EE
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMKLPSSSTWGQQSNTTAC 959
L Q+++++ RQ ++ QE ++Q+Q++ ++Q +M+ W ++
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
+ +I++LEE+ Q + ++ ++R+ + +++Q+++Q+Q+ W K
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK---- 391
Query: 1020 TKSLLEIQQEEARQMQKQQQQQQQ 1043
+ Q+E+ R+ ++ Q+Q++
Sbjct: 392 ----IREQEEKIREQEEMMQEQEE 411
Score = 40.8 bits (94), Expect = 0.009
Identities = 74/411 (18%), Positives = 157/411 (38%), Gaps = 66/411 (16%)
Query: 890 EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 949
+E+ A +H+E R+ E +VQ + L Q+ + Q AL Q +Q + L S
Sbjct: 97 DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 155
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 1002
S A + + LS QK + +R +L +E+ EL + L+++ +
Sbjct: 156 --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 213
Query: 1003 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
Q+KL + L+ + E A+ + QQQ Q + + + + L +
Sbjct: 214 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 1063 -GNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1121
N +W N N+ +
Sbjct: 274 EENELW-------------------------------------------NRLNQQQEEKM 290
Query: 1122 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1181
+ + R+ K E+EEK+ + + + + ++ + E+M +
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-----EK 345
Query: 1182 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1241
++E+E + IR E ++ +Q E+R +Q+A RQ++++ +Q+++ Q+
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 1242 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVR 1292
+ Q+Q+ G +++ + +Q Q K ++++K +R
Sbjct: 404 --EMMQEQEEKMGEQE---EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 135 bits (340), Expect = 3e-31
Identities = 118/463 (25%), Positives = 233/463 (50%), Gaps = 59/463 (12%)
Query: 630 RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 689
RL +QQE Q + +Q + IQ+Q ++ Q++K ++ ++ ++ + + KM
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 351
Query: 690 RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGS-VWDLPLDTTTPGPALEQ 746
R ++ + + + +WE + + +WE + +L EQ
Sbjct: 352 RRQEEMMWEKEEKMRRQEEM--MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---------EE 797
++ ++ + + +++R+E E + R+EE+ + QEE R+QE+ + RQ+E EE
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 798 RKRREEEELARRK------------------QEEALRRQRE----QEIALRRQRE----- 830
KR+E+EE+ R++ QEE +R+Q E QE +R Q E
Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 831 EEERQQQEEALRRLEERRREEEERRKQEELL---RKQEEEAAKWAREEEEAQRRLEENRL 887
EE+ +QEE +R EE REEE+ +QE++ ++QE+E W +EE R EE
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW--RQEEKIREQEEKVW 587
Query: 888 RMEEEAARLRHEEEERKRKELEVQRQKELMRQR----QQQQEALRRLQQQQQQQQLAQMK 943
R EE ++R +EE+R+ +E ++ +Q+E +R++ Q+Q+E +R +++ ++Q+ +M
Sbjct: 588 RQEE---KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE--EMT 642
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
G+Q Q + E +EE+ R+ +E++ R+Q E ++ ++ Q+Q
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE-QEKKIREQEEKIREQEEMMQEQ 701
Query: 1004 QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046
++K+ W K + + E +++ RQ +K +Q+ + +Q
Sbjct: 702 EEKM--WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Score = 122 bits (307), Expect = 2e-27
Identities = 103/408 (25%), Positives = 207/408 (50%), Gaps = 64/408 (15%)
Query: 628 QERLTRQQELT-----ALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQ 682
+E++ RQ+E+ + +++ ++Q I++Q + +++K ++Q+Q A + +
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWR 434
Query: 683 QFQTLKMRISDQNIIPSVTR----SVSVPDTGSIWELQPTASQPTVW-------EGGSVW 731
Q + K+R ++ I + + + I E + Q +W E +W
Sbjct: 435 QEE--KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 732 DLPLDTTTPGPALEQLQQLEKA--KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI 789
EQ +++ K K + E++ RE E + + +EE+ RQEE R+QEE+
Sbjct: 493 ------RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546
Query: 790 LRRQQEEERKRREEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEA 840
R +++ + + EE R++QE+ + RQ REQE + RQ E EE+RQ+QEE
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 841 LRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
+ + EE+ RE+EE+ ++QEE +R+QEE+ + +E + ++ E +M E+ +++ +
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
EE R+E +++ Q++ +R+ Q+E +R ++ Q+Q+ W Q+
Sbjct: 667 EETMWRQEEKIREQEKKIRE---QEEKIREQEEMMQEQE--------EKMWEQEE----- 710
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 1007
+ E+E + Q +EE+ R+Q E M + + +QQ++K+
Sbjct: 711 -----------KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
Score = 109 bits (272), Expect = 2e-23
Identities = 82/307 (26%), Positives = 165/307 (53%), Gaps = 45/307 (14%)
Query: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
+QE + RQ+E +++ + + Q+ + +Q ++ Q++K ++ ++ Q
Sbjct: 474 EQEEMWRQEE--KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE--------QE 523
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIW-ELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 745
K+R ++ + + + + +W E + Q +WE E
Sbjct: 524 EKIREQEEKMW---RQEEKIREQEEMWREEEKMHEQEKIWE------------------E 562
Query: 746 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE--- 802
+ +Q ++ K + E++ RE E + R+EE+ + QEE R++QEE + +Q+E+ R++ E
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 803 EEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEE 853
E+E R+QEE +R Q +EQE + Q E EE+ Q+QEE + R EE+ RE+E+
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 854 R-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 912
+ R+QEE +R+QEE + + E + ++ E +M+E+ ++R +EE+ +E+ +++
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Query: 913 QKELMRQ 919
Q+E M++
Sbjct: 743 QEEKMQE 749
Score = 105 bits (262), Expect = 3e-22
Identities = 67/209 (32%), Positives = 126/209 (60%), Gaps = 14/209 (6%)
Query: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKR 800
+ + +++ + + EQE+ E + + +E++ RQEE R+QEE + RQ+E E+ ++
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
Query: 801 REEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREE 851
R+E+E KQEE +R Q +EQE +R Q E EE Q+QEE + EE+ E+
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
Query: 852 EER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 910
EE+ ++QEE + +QEE+ + ++ E + ++ E M+E+ ++ +EE+ +E ++
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Query: 911 QRQKELMRQRQQQQ-EALRRLQQQQQQQQ 938
Q Q+E MR+++++ E RL+QQ+++ Q
Sbjct: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 101 bits (251), Expect = 5e-21
Identities = 116/561 (20%), Positives = 249/561 (44%), Gaps = 73/561 (13%)
Query: 732 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 791
+L +T T E+ +L++ K +E E+ E ++ K + + +R + L QQ+
Sbjct: 208 ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 262
Query: 792 RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 850
Q E + +E + ++ + Q + E E+ R Q++EE+ +QEE ++ EE+ +E
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318
Query: 851 EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 892
+EE+ R+QEE +R+QEE E W +EE EE RR EE EE+
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Query: 893 AARLRHE--EEERKRKELE--VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
R E+E K +ELE + Q+++ Q +++QE + +Q+++Q+Q A+M
Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 949 TWGQQSNTTACQS---QATLSLAEIQKLEEERERQLREEQRRQQ----------RELMKA 995
Q+ + + + E +K+ EE +RQ +EE RQ+ R+ K
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM 498
Query: 996 LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTH 1055
+Q+++ ++Q+ W K + + E +++ RQ +K ++Q++ ++ +
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ-- 556
Query: 1056 SNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNAD-TKNSNMGFW--DDAVKEVGPRNS 1112
+W + + +W + + W ++ ++E +
Sbjct: 557 --------EKIW-------EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Query: 1113 TNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANN 1172
+ K + K Q +K++E+E+ ++ + + Q+ TQ E+ +
Sbjct: 602 EQEEK----MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE---KMGEQEE 654
Query: 1173 LDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQ 1232
++ E+ + + IR E +E ++ E +Q+ Q++++ +
Sbjct: 655 KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714
Query: 1233 QQQQQPPQQPPQQPQQQDSVW 1253
Q+++ Q+ + +Q++ +W
Sbjct: 715 QEEKMQEQEEKMR-RQEEKMW 734
Score = 85.5 bits (210), Expect = 3e-16
Identities = 95/546 (17%), Positives = 227/546 (41%), Gaps = 49/546 (8%)
Query: 757 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 816
+L +ER + R + +E + +E L+ + E+ + + + +RK E A
Sbjct: 197 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 256
Query: 817 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR-KQEEEAAKWAREE 875
+Q++ +E Q L+ E +Q+E +QEE+ +W +
Sbjct: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316
Query: 876 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ 935
+E + ++ E ++ E+ ++R +EE KE +++RQ+E+M +++++ R Q++
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM----RRQEEMM 372
Query: 936 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER--ERQLREEQRRQQRELM 993
++ +M+ W ++ + + +I++ EE+R E ++RE+++RQ++E
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 994 ------KALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1047
K +Q+++ ++Q+ W K K E +++E +M +Q+++ + ++
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Query: 1048 NRARNNTHSNLH--TSIGNSVW-GSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAV 1104
R + H VW + + +W + W +
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 1105 KEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQML 1164
K + K K RQ +K+ E+E+ K+++ K ++ + EQ
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMW----RQEEKIREQEE--KVWRQEEKIREQEEKRQEQ-- 603
Query: 1165 HALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQ 1224
E ++ + IR E +E ++ E+ +Q+ Q
Sbjct: 604 --------------------EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 1225 RQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKK 1284
Q++++ +Q+++ Q+ Q +Q++++W Q + Q+ + +
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQ-EQEETMWRQEEKIRE---QEKKIREQEEKIREQEEMMQ 699
Query: 1285 KKKQKM 1290
++++KM
Sbjct: 700 EQEEKM 705
Score = 57.4 bits (137), Expect = 9e-08
Identities = 97/548 (17%), Positives = 214/548 (39%), Gaps = 97/548 (17%)
Query: 802 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 835
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 836 --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 883
+ E+AL + ++++ EE K+ + L + E +E +L+
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 884 ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943
E +E E + ++ +E KRK ++R K L+ Q+Q Q EA ++ Q Q +
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERER-QLREEQRRQQRELMKALQQQQQQ 1002
+ + W + + Q Q + +K++E E+ Q +EE+ R+Q E K +Q+++
Sbjct: 285 VEENELWNRLN-----QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE--KIREQEEKM 337
Query: 1003 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
++Q+ W K + E+ E+ +M++Q++ + ++ R +
Sbjct: 338 RRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE---------- 383
Query: 1063 GNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASL 1122
+W + +L + + + +E R + + A +
Sbjct: 384 -EMMW------EKEEKIRELEEKMHEQEKIREQE----EKRQEEEKIREQEKRQEQEAKM 432
Query: 1123 SKSVGVSNRQNKKVEEEEKLL-----KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPT 1177
+ Q +K+ E+EK + K+ + ++ Q E+M + +
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE--- 489
Query: 1178 FVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ--- 1234
++ E +E + IR +E ++ E+ +Q+ RQ++++ +Q+
Sbjct: 490 --EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 1235 -------QQQPPQQPPQQPQQQDSVWGMNHSTL---HSVFQTNQSNNQQSNFEAVQSGKK 1284
+Q+ + ++ +Q+D +W V++ + +Q Q K
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Query: 1285 KKKQKMVR 1292
K+++ +R
Sbjct: 608 WKQEEKIR 615
Score = 42.0 bits (97), Expect = 0.004
Identities = 49/239 (20%), Positives = 94/239 (39%), Gaps = 38/239 (15%)
Query: 214 RKHEFIRSESENWR----------IFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPDG 261
R+ E IR + E WR I+ EE+ E ED WR R+ E WR
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR------ 588
Query: 262 PRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGT 321
+ RE E+R+ E +++ ++R I + + + E + E+E
Sbjct: 589 -QEEKIREQEEKRQEQEEKMWKQEE-----KIREQEEKIQEQEEKIREQEEKIREQE--- 639
Query: 322 FDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKT 381
+ + Q+E + E++E ++ +E ++ E+ +E +K +++ EK
Sbjct: 640 --------EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 382 DRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTE---KAEEETRMEN 437
+E + + + QE + R+ E K + E + +EE E+
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 134 bits (338), Expect = 4e-31
Identities = 133/575 (23%), Positives = 263/575 (45%), Gaps = 73/575 (12%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE----EERKR 800
E ++LE+AK + + + R+EEE + QE+ R+QEE + RQ+E +E K
Sbjct: 212 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
Query: 801 REEEELARRKQEEALRRQ----REQEIALRRQR----EEEERQQQEEALRRLEERRREEE 852
RE+EE RR QE+ LR Q REQE LR Q+ +EE+ Q+QEE + EE+ RE+E
Sbjct: 272 REQEEKMRR-QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 853 ERR-KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
E+ +QEE L +QE++ RE+E+ R EE RM E+ RLR E+EER R++ ++
Sbjct: 331 EKMWRQEERLWEQEKQM----REQEQKMRDQEE---RMWEQDERLR-EKEERMREQEKMW 382
Query: 912 RQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMKLPSSSTWGQQSNTTACQS--QATLSL 967
Q+E M++ ++ +E ++++++++ ++Q +M+ + W Q+ Q + L
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 968 AEIQKLEEERERQLREEQRRQQRELM----KALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1023
E +K++E+ E+ +E++ + +E M K + +Q++ ++Q+ W
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW------------- 489
Query: 1024 LEIQQEEARQMQKQQ---QQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS 1080
+QEE + Q+Q+ Q+++ +Q R R W
Sbjct: 490 ---EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK--------------KMWQQ 532
Query: 1081 DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE 1140
+ + T+ WD K R + + + + Q +K++E+E
Sbjct: 533 E--EKMREEKKTQEQEKKTWDQEEKM---REEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 1141 KLL-----KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYI 1195
+ + K+++ K Q+ + EQ + + E E + +
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 1196 RAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGM 1255
+ +E + E + + + + R+Q++ Q Q+++ +Q + Q++ +WG
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Query: 1256 NHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1290
+ + E ++ K+K ++++
Sbjct: 708 EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Score = 127 bits (320), Expect = 5e-29
Identities = 118/493 (23%), Positives = 234/493 (47%), Gaps = 84/493 (17%)
Query: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
+QE R+QE Q + L+ Q+ +++Q ++ Q++ Q Q+Q + +Q +
Sbjct: 266 EQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE- 324
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA---SQPTVWEGGSVWDLPLDTTTPGPA 743
KMR ++ + R +WE + Q + +W+
Sbjct: 325 -KMREQEEKMWRQEER---------LWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374
Query: 744 LEQLQQLEKAKAAKLEQER-REAEMRAKREEEERKRQEELRRQQEEILRRQQEEE----- 797
+ + +++ + + E+ER RE E + + EEE + QEE ++QEE + Q+E+E
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 798 ----------RKRREEEELARRKQEEALRRQRE---QEIALRRQ---REEEERQ------ 835
+++ +E+E +QEE +R Q E QE + RQ RE+E++
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 836 ----------------QQEEALRRLEERRREEEERRKQEELLRK----QEEEAAKWAREE 875
+Q+E LR EER RE+++ +QEE +R+ QE+E W +EE
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
Query: 876 E-EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM-RQRQQQQEALRRLQQQ 933
+ + R+ E +M EE +R +EE+ + +E +++ Q+E M Q ++ QE ++ +Q
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Query: 934 Q----QQQQLAQMKLPSSSTWG-----QQSNTTACQSQATLSLAEIQKLEEERERQLREE 984
+ +Q++ +M+ W Q+ + + + E + E+E + Q +EE
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Query: 985 QRRQQRELMKALQQQQQQQQQKLSG-----WGNVSKPSGTTKSLL---EIQQEEAR---Q 1033
+ R+Q E M+ +++ ++Q++K+ G WG K G + + E++++E R Q
Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Query: 1034 MQKQQQQQQQHQQ 1046
+K Q++ +H++
Sbjct: 735 KEKMQERLPEHEE 747
Score = 125 bits (313), Expect = 3e-28
Identities = 113/469 (24%), Positives = 223/469 (47%), Gaps = 79/469 (16%)
Query: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
+QE+ R+QE Q + L+ Q+ +++Q ++ Q+++ L Q+++ + +
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR--LREQEKELREQEKELREQ 302
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R ++ + + + E + + +WE ++
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE------------------QE 344
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ---EEERKRREE 803
Q E+ + + ++ER + RE+EER R++E +QEE ++ ++ E E+K REE
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 804 EELAR------RKQEEALRRQREQEIALRRQREEEER-------QQQEEALRRLEERRRE 850
EE R +KQEE + Q E+E +R E++E+ Q+QEE + EE+ R+
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464
Query: 851 EEE-------------RRKQEELLRKQEE-----EAAKWAREEE--EAQRRLEENRLRME 890
+EE R+QE+ + +QEE E W +EE E RL E RM
Sbjct: 465 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524
Query: 891 EEAARLRHEEEERKRKELEVQ-----------RQKELMRQRQ---QQQEALRRLQQQQQQ 936
E+ + EE+ R+ K+ + Q R++E MR+R+ +++E + R Q+++ Q
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 937 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 996
+Q +M+ W Q+ Q Q + +K+ E+ E E++ ++Q E+M
Sbjct: 585 EQEEKMREQEEKMWEQEEK---MQEQEEKMWEQEEKMWEQEE----EDKMQEQEEMMWEQ 637
Query: 997 QQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
+++ Q+Q++K+ W K + + E +++ Q +K ++Q+++ Q
Sbjct: 638 EEKMQEQEEKM--WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Score = 102 bits (254), Expect = 2e-21
Identities = 91/333 (27%), Positives = 164/333 (49%), Gaps = 41/333 (12%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E Q+RL Q+E L++ + +Q Q+ I +Q ++ Q++ + +Q + Q+
Sbjct: 429 EWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 685 QTL----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGSVWDLPLDTT 738
Q KMR +Q + R +WE + + E +W
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEER---------MWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 739 TPGPALEQLQQLEKAKAAKLEQER-REAEMRAKREEEERKRQEELRRQQEEILRRQ---- 793
EQ ++ + E+ER RE E + + EEE + QEE ++QEE +R Q
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 794 -------QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE 846
QE+E K E+EE ++EE +++E+ + +EE+ Q+QEE + EE
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM----WEQEEKMQEQEEKMWEQEE 653
Query: 847 RRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 905
+ RE+EE+ R+QEE ++ QEE+ RE+EE + EE +M E+ ++R +EE+
Sbjct: 654 KMREQEEKMREQEEKMQGQEEK----MREQEEKMQGQEE---KMREQEEKMRGQEEKMWG 706
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 938
+E ++ Q+E M +++ +E R++ Q+++ Q
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Score = 92.4 bits (228), Expect = 3e-18
Identities = 97/553 (17%), Positives = 233/553 (42%), Gaps = 68/553 (12%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
AL + K +E+ +E + + EEL+++ E+ +E+ + E
Sbjct: 146 ALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL-----QEKLRLAE 200
Query: 803 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 862
E+ + + L+R+ E+ L Q + QEE R+ EE R +E++ RKQEE +
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 258
Query: 863 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 922
+QEE E+E + R +E ++R +E+ RLR +E+E + +E E++ QK+L Q +Q
Sbjct: 259 RQEERL-----REQEGKMREQEEKMRRQEK--RLREQEKELREQEKELREQKKLREQEEQ 311
Query: 923 QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 982
QE ++ +Q+++ + + K+ W Q+ ++L E+
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKM-----WRQE-----------------ERLWEQ------ 343
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQ 1042
E+Q R+Q + M+ +++ +Q ++L + E QEE R +++++ ++
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 1043 QHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDD 1102
+ + ++W Q + +W + W+
Sbjct: 404 EEETMREQEEKMQKQ-----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458
Query: 1103 AVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQ 1162
K + K + + + ++++ E+EEK+ Q + ++ + E+
Sbjct: 459 EEKIRDQEEMWGQEK---KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 1163 MLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAK----EFAKQFLERRAK 1218
+ ++E + ++ + +R + K + K E R +
Sbjct: 516 LREKEER------------MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 1219 QKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEA 1278
++ + R+++++ ++Q+++ +Q + +Q++ +W + ++ +E
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEKMWEQEEKMWEQ 621
Query: 1279 VQSGKKKKKQKMV 1291
+ K +++++M+
Sbjct: 622 EEEDKMQEQEEMM 634
Score = 66.2 bits (160), Expect = 2e-10
Identities = 79/375 (21%), Positives = 164/375 (43%), Gaps = 34/375 (9%)
Query: 504 DDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQ 563
++EE ++ E++ +K + + + E +L E + K M E +K + ++ +
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 564 GEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHM 623
Q QE W Q M + ++ + KMW + M
Sbjct: 462 IRDQEEMWGQEKKMWRQE---KMREQEDQMWEQEEKMRDQEQKMWDQ---------EERM 509
Query: 624 GELDQ---ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALL 680
E D+ E+ R +E ++Q + ++ Q+Q + Q++K + +++ +
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 681 LQQFQTL-----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPL 735
++ + + KM+ ++ + + + E + + +WE +
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
Query: 736 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 795
E++Q+ E+ K + E++ RE E + + +EE+ + QEE R+QEE + Q +
Sbjct: 630 QEEMMWEQEEKMQEQEE-KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE--KMQGQ 686
Query: 796 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 855
EE+ R +EE++ R QEE + Q E + +EE+ +E +R EER R+++E
Sbjct: 687 EEKMREQEEKM--RGQEEKMWGQEE------KMWGQEEKMWGQEEMREKEERIRDQKE-- 736
Query: 856 KQEELLRKQEEEAAK 870
K +E L + EE ++
Sbjct: 737 KMQERLPEHEERCSE 751
Score = 58.5 bits (140), Expect = 4e-08
Identities = 90/508 (17%), Positives = 196/508 (38%), Gaps = 51/508 (10%)
Query: 802 EEEELARRKQEEALRRQREQE------IALRRQREEEERQQQEEALRRLEERRREEEERR 855
E+E+ A + +EALRR+ E + + ++ E ++A R+ E+ E +
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 856 KQE--------ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 907
L++ + W ++ + L + R + E R EE K+K
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
Query: 908 LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 967
E+ Q++L ++ E +++ +++ + A+ LP T Q + +
Sbjct: 190 AEL--QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
Query: 968 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
+I+K EE+ RQ EE+ R+Q M+ +++ ++Q+++L + K L E +
Sbjct: 248 KKIRKQEEKMWRQ--EERLREQEGKMREQEEKMRRQEKRLREQEKELREQ--EKELREQK 303
Query: 1028 QEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVW-GSINTGPPNQWASDLVSSI 1086
+ ++ Q Q+Q+++ +Q + R +W Q D +
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE--ERLWEQEKQMREQEQKMRDQEERM 361
Query: 1087 WSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLF 1146
W + KE R + + + + R+ K EEEE + +
Sbjct: 362 WEQDERLRE---------KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412
Query: 1147 QGVNKAQDGF-----TQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1201
+ + K ++ +W +Q L P L E E E + I
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRL-----------PEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 1202 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLH 1261
+ +E Q E++ ++ + Q+ Q+ +Q+++ Q+ + Q++ +W +
Sbjct: 462 IRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQEEKMRDQE-QKMWDQEERMWEQDERLRE 518
Query: 1262 SVFQTNQSNNQQSNFEAVQSGKKKKKQK 1289
+ + E ++ KK ++Q+
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQE 546
Score = 45.4 bits (106), Expect = 4e-04
Identities = 45/231 (19%), Positives = 94/231 (40%), Gaps = 21/231 (9%)
Query: 212 VGRKHEFIRSESENW----RIFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPDGPRSA 265
+ + E IR + E W +++R+E+ E ED W RD E+ W +
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 266 GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSS 325
RE ER R + ++ + R ++ + D + + E EE M +
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE------EERMREREK- 567
Query: 326 GAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVG 385
K ++E + EQE + ++ E+ + E E+ ++ + +K E+ +++
Sbjct: 568 ------KMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 386 VASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRME 436
EE Q QE +E++++ + ++ + E+E +M+
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 134 bits (337), Expect = 6e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 629 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 688
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 193 EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
Query: 689 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 739
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
Query: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
Query: 800 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 854
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 855 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 901
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 959
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 1018
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 1019 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1046
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 110 bits (275), Expect = 9e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 801
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 920
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 921 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 980
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Query: 981 LREEQRRQQRELMKALQQ 998
++ R ++ + A QQ
Sbjct: 605 QQDHYRGHLQQYVAAYQQ 622
Score = 97.4 bits (241), Expect = 8e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 745 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
Query: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
Query: 862 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Query: 920 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Query: 974 EEERE 978
+E
Sbjct: 624 ASGKE 628
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 134 bits (337), Expect = 6e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 629 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 688
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 193 EKLTKERDALSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
Query: 689 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 739
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
Query: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
Query: 800 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 854
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 855 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 901
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 959
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 1018
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 1019 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1046
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 110 bits (275), Expect = 9e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 801
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 920
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 921 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 980
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Query: 981 LREEQRRQQRELMKALQQ 998
++ R ++ + A QQ
Sbjct: 605 QQDHYRGHLQQYVAAYQQ 622
Score = 97.4 bits (241), Expect = 8e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 745 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
Query: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
Query: 862 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Query: 920 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Query: 974 EEERE 978
+E
Sbjct: 624 ASGKE 628
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 134 bits (336), Expect = 8e-31
Identities = 101/332 (30%), Positives = 176/332 (53%), Gaps = 37/332 (11%)
Query: 741 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQ---- 794
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+
Sbjct: 108 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 795 EEERKRREEEELARR-------------KQEEALRRQREQ--EIALRRQREEEERQQQEE 839
E+E + RE+E R +QE + Q EQ E + Q++EE+ +QEE
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 840 ALRRLEERRREEEER-RKQEELLRKQEEEAAK---WAREEEEAQRRLEENRLRMEEEAAR 895
+R+ EE+ E+EE+ +KQEE ++KQEE+ K RE+EE R EE L+ +E+
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-- 285
Query: 896 LRHEEEERKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQ 952
+EE+ +E +++ Q+E MR++++Q QE R Q++Q +Q QM W Q
Sbjct: 286 --EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 953 QSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGN 1012
+ + Q ++QK EE+ +Q EEQ R+Q E M+ ++Q ++Q++++ G
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQ--EEQMRKQEEQMRKQEEQMRKQEEQM---GE 398
Query: 1013 VSKPSGTTKSLLEIQQEEARQMQKQQQQQQQH 1044
+ G K + Q+E+ + ++Q ++Q++H
Sbjct: 399 QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Score = 128 bits (322), Expect = 3e-29
Identities = 102/410 (24%), Positives = 210/410 (51%), Gaps = 45/410 (10%)
Query: 602 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVL 661
G + + G+V G +QE R+QE Q ++ Q+ +++Q QV
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
Query: 662 AQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQ 721
Q+ + +Q+ Q+ Q + + ++ +Q G + E + +
Sbjct: 126 EQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Query: 722 PTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE 781
+ G V + G Q+ + E+ + EQ +++ E ++EE+ RK++E+
Sbjct: 183 ----QEGQVRE---QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
Query: 782 LRRQQEEILRR----QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-Q 836
+ Q+E++ ++ Q++EE+ R++EE++ R+QEE +R Q EQ + + Q E+EE+ +
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQM--REQEEQMREQEEQMLKQKEQTEQEEQTGE 293
Query: 837 QEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 895
QEE +R EE+ RE+EE+ R+QEE +R+QEE+ K + E + ++ E + +M ++ +
Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
Query: 896 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 955
+ +EE+ +++E +V++Q+E MR++++Q R Q++Q ++Q QM G+Q
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQM----RKQEEQMRKQEEQM--------GEQKE 401
Query: 956 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
Q E++ + + +EEQ +Q+E M+ ++ +Q++
Sbjct: 402 ---------------QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 119 bits (299), Expect = 1e-26
Identities = 93/315 (29%), Positives = 162/315 (51%), Gaps = 51/315 (16%)
Query: 741 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
Query: 799 KRRE---EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER- 854
++ E+E +QEE + Q EQ Q++EE+ +QEE +R+ EE+ E+EE+
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 855 RKQEELLRKQEEEAAKWA---REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
+KQEE ++KQEE+ K RE+EE R EE L+ +E+ +EE+ +E +++
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMR 299
Query: 912 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 971
Q+E MR++++Q R Q++Q ++Q QM W Q+ + Q + E Q
Sbjct: 300 EQEEQMREQEEQM----REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQEEQ 353
Query: 972 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1031
E+E + Q +EEQ R+Q E M+ ++Q ++Q++
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-------------------------- 387
Query: 1032 RQMQKQQQQQQQHQQ 1046
QM+KQ++Q + ++
Sbjct: 388 -QMRKQEEQMGEQKE 401
Score = 108 bits (269), Expect = 4e-23
Identities = 88/317 (27%), Positives = 166/317 (52%), Gaps = 20/317 (6%)
Query: 741 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111
Query: 799 KRREEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER 854
E+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E +
Sbjct: 112 ----EQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQ 165
Query: 855 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
R+QE +R+QE + + + E + ++ E +M E+ ++ +EE+ +++E ++ Q
Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
Query: 914 KELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 970
+E MR++++Q QE + Q++Q Q+Q QM+ Q+ + Q L +
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQK 282
Query: 971 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-SGWGNVSKPSGTTKSLLEIQQE 1029
++ E+E + +EEQ R+Q E M+ ++Q ++Q++++ + K E E
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 1030 EARQMQKQQQQQQQHQQ 1046
+ QM KQ++Q + ++
Sbjct: 343 QKEQMWKQEEQMGEQEE 359
Score = 105 bits (263), Expect = 2e-22
Identities = 83/318 (26%), Positives = 167/318 (52%), Gaps = 27/318 (8%)
Query: 751 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR---EEEELA 807
++ + + E + RE E + + +E + + QE R+QE +R Q+ + R++ E+E
Sbjct: 50 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109
Query: 808 RRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEELLR 862
R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE +R
Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 863 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 922
+QE + + + E + ++ E +M E+ ++ +EE+ +E ++Q+Q+E M ++++
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 923 Q----------QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK 972
Q QE + Q++Q Q+Q QM+ Q+ + Q + ++
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 973 LEE--ERERQLR--EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028
E+ E+E Q+R EEQ R+Q E M+ ++Q ++Q++++ G + K + Q+
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM---GKQEEQMWEQKEQMWEQK 344
Query: 1029 EEARQMQKQQQQQQQHQQ 1046
E+ + ++Q +Q++ Q
Sbjct: 345 EQMWKQEEQMGEQEEQMQ 362
Score = 103 bits (258), Expect = 8e-22
Identities = 82/314 (26%), Positives = 166/314 (52%), Gaps = 17/314 (5%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREE 803
E ++L+ + K E + E++ K E ++ +E + R+QE +R Q+ + R E
Sbjct: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR----E 70
Query: 804 EELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQE 858
+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE
Sbjct: 71 QEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQE 128
Query: 859 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918
+R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+ Q+ +R
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
Query: 919 QRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 975
+++ Q QE Q++Q +Q QM+ Q+ + Q ++QK EE
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
Query: 976 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1035
+ ++Q EEQ R+Q E M+ ++Q ++Q++++ ++ T E +E+ QM+
Sbjct: 249 QVQKQ--EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 1036 KQQQQQQQHQQPNR 1049
+Q++Q ++ ++ R
Sbjct: 307 EQEEQMREQEEQMR 320
Score = 92.4 bits (228), Expect = 3e-18
Identities = 75/284 (26%), Positives = 147/284 (51%), Gaps = 12/284 (4%)
Query: 772 EEEERKRQEELRRQQEEILRRQQE-EERKRREEEELARRKQEEALRRQ----REQEIALR 826
+E+ + QEEL+ + E Q +E KR+ E + QE +R Q REQE +R
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
Query: 827 RQREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEEN 885
Q E + ++QE +R E + RE+E + R+QE +R+QE + + + E + ++ E
Sbjct: 70 EQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
Query: 886 RLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ---QQQEALRRLQQQQQQQQLAQM 942
++ E+ ++R +E + + +E +V+ Q+ +R+++ ++QE R Q+ Q ++Q Q+
Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
Query: 943 KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ 1002
+ Q+ + Q ++QK EE+ Q E+ R+Q+ ++ + +Q Q+Q
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQ 246
Query: 1003 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046
++Q + K + E +E+ QM KQ++Q +Q +Q
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
Score = 77.4 bits (189), Expect = 8e-14
Identities = 83/454 (18%), Positives = 202/454 (44%), Gaps = 39/454 (8%)
Query: 794 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-QQEEALRRLEERRREEE 852
+E+ + +EE +L ++ E +E L+R+ E ++ QE +R E + RE+E
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKE----LKRKLETDKIPLPQEGQVREQEGQVREQE 65
Query: 853 ER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
+ R+QE +R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
Query: 912 RQKELMRQRQ---QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968
Q+ +R+++ ++QE R Q+ Q ++Q Q++ Q+ + Q
Sbjct: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Query: 969 EIQKLE---EERERQL--REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1023
++++ E E+E Q+ +EEQ +Q E M+ ++Q +Q++++ + G +
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242
Query: 1024 LEIQQEEARQMQKQ--QQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASD 1081
++ Q+E+ ++ ++Q +Q++Q +Q + R L TG + +
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK--EQTEQEEQTGEQEEQMRE 300
Query: 1082 LVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEK 1141
+ + + +++G + + + + ++ + E+EE+
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 1142 LLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1201
+ K + V K ++ + EQM K+ E + + +
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQM------------------RKQEEQMRKQEEQMGEQKEQ 402
Query: 1202 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQ 1235
E KE ++ E+ +QK ++Q++ + +Q++
Sbjct: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 60.8 bits (146), Expect = 8e-09
Identities = 78/478 (16%), Positives = 196/478 (41%), Gaps = 89/478 (18%)
Query: 843 RLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 902
R+ +E+ QEEL + E E ++ +E +R+LE +++ + +E ++R +E +
Sbjct: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQ 60
Query: 903 RKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
+ +E +V+ Q+ +R+++ Q QE R Q+ Q ++Q Q++ Q+
Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
+ Q +++ E+E Q+RE++ + + + + +Q+ Q ++Q+ G V + G
Sbjct: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE----GQVREQEG- 171
Query: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1079
+++++E + +++ Q ++Q Q
Sbjct: 172 -----QVREQEGQVREQEGQVREQEGQMGE------------------------------ 196
Query: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
+ MG + +++G + + + + + ++ + E+E
Sbjct: 197 -------------QEGQMG---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199
E++ K + V K ++ + EQM ++ E E + +
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMR------------------EQEEQMREQEEQMLKQK 282
Query: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259
T + ++ +Q E + +++ Q R+Q++ ++Q++Q +Q Q +Q++ +W
Sbjct: 283 EQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Query: 1260 LHSV----FQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGE 1313
Q Q Q+ + + +K++++M + + + + MGE
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Score = 35.8 bits (81), Expect = 0.28
Identities = 33/193 (17%), Positives = 79/193 (40%), Gaps = 8/193 (4%)
Query: 268 REHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGA 327
RE + R E R+++ + VR G + + + E + E+E + G
Sbjct: 97 REQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 151
Query: 328 FLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVA 387
+ +E + +E + + ++ + + EG E+ + + + GE+ +++G
Sbjct: 152 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ 211
Query: 388 SEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRG 447
E+ + Q ++ + E + + + EQ +K EE+ R + ++ +
Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE---QMREQE 268
Query: 448 DEMVADVQQPLSQ 460
++M +Q L Q
Sbjct: 269 EQMREQEEQMLKQ 281
Score = 33.5 bits (75), Expect = 1.4
Identities = 29/172 (16%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Query: 268 REHMERRRRFEFDFRDRD----DERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFD 323
RE + R E R+++ ++ G R + G + + E + + EE+MG +
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
Query: 324 SSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDR 383
++K +++ +E++M + GE+ + + K+ ++ K+E + ++
Sbjct: 213 EQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
Query: 384 VGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRM 435
E+ Q + QE E++++ + ++ + E+E +M
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Score = 32.3 bits (72), Expect = 3.1
Identities = 35/222 (15%), Positives = 82/222 (36%), Gaps = 31/222 (13%)
Query: 212 VGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHM 271
V ++ E ++ + E R E+ ++E + + E+ G + RE
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
Query: 272 ERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSL 331
E+ R E R+++++ + + EE+MG +
Sbjct: 303 EQMREQEEQMREQEEQ------------------------MREQEEQMGKQEEQ------ 332
Query: 332 KKVQKEPIPEEQEMDFRPVDE-GEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEE 390
QKE + E++E ++ ++ GE+ + + K+ ++ K+E + + ++
Sbjct: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Query: 391 TPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEE 432
Q + G + ++ Q + E +Q E E+
Sbjct: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQ 434
Score = 31.6 bits (70), Expect = 5.3
Identities = 31/194 (15%), Positives = 76/194 (39%), Gaps = 5/194 (2%)
Query: 268 REHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGA 327
RE + R E R+++ + VR G + + + E + E+E + G
Sbjct: 90 REQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 144
Query: 328 FLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVA 387
+ +E + +E + + ++ + + EG E+ + + + GE+ ++G
Sbjct: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204
Query: 388 SEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRG 447
E+ + + Q ++ + E + + EQ +K EE+ + + K +
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 448 DEMVADVQQPLSQI 461
E +++ Q+
Sbjct: 265 REQEEQMREQEEQM 278
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 127 bits (320), Expect = 5e-29
Identities = 105/431 (24%), Positives = 215/431 (49%), Gaps = 75/431 (17%)
Query: 630 RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 689
RL +QQE Q + +Q + IQ+Q ++ Q++K ++ ++ ++ + + KM
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 351
Query: 690 RISDQNIIPSVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGPALEQL 747
R ++ +WE + + +WE E++
Sbjct: 352 RRQEE----------------MMWEKEEKMRRLEEMMWEKE----------------EKI 379
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 807
++LE+ K+ ++ + E KR+EEE+ R++E R++QE + RQ EE+ R +EE++
Sbjct: 380 RELEE----KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKI- 432
Query: 808 RRKQEEALRRQREQEIALRRQREEEERQQQEEALR------------RLEERRREEEERR 855
R+QE+ + RQ E+ + REEE+RQ+QEE R R +E+ E+E+ R
Sbjct: 433 -REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 856 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 915
KQEE + +QEE+ ++EE R EE R EE ++R +EE+ + +E +++ Q+E
Sbjct: 492 KQEEKVWRQEEK----MHDQEEKIREQEEKMWRQEE---KIREQEEKIREQEEKIREQEE 544
Query: 916 LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 975
+M++++++ Q+Q++ + + K+ ++ + + + E + E+
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ 604
Query: 976 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1035
E Q +EE+ +Q E M +++ Q+Q++K+ + E E+ +++
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM-------------RRQEEKMWEQEVRLR 651
Query: 1036 KQQQQQQQHQQ 1046
+Q+++ Q+HQ+
Sbjct: 652 QQEEKMQEHQE 662
Score = 122 bits (305), Expect = 3e-27
Identities = 93/339 (27%), Positives = 183/339 (53%), Gaps = 40/339 (11%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER------ 798
E++++ E+ K E+ RR EM ++EE+ R+ +E++ +QE+I R+QEE+R
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-EQEKI--REQEEKRQEEEKI 405
Query: 799 ---KRREEEELARRKQEEALRRQ----REQEIALRRQRE---EEERQQQEEALRRLEERR 848
++R+E+E +QEE +R Q REQE + RQ E E+E+ ++EE + EE
Sbjct: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 849 REEEERRKQEELLRKQEE--EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 906
R+EE+ R+QEE+ R++E+ E K ++EE+ R+ E +M ++ ++R +EE+ R+
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE----KMHDQEEKIREQEEKMWRQ 521
Query: 907 ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLS 966
E +++ Q+E +R +Q+E +R ++ Q+Q+ G+Q Q +
Sbjct: 522 EEKIREQEEKIR---EQEEKIREQEEMMQEQE---------EKMGEQEEKMQEQEKMRRQ 569
Query: 967 LAEIQKLEE---ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1023
+I++ EE E++ ++RE++ + + K +Q++ Q+Q+ W K + +
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629
Query: 1024 LEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
E +++ RQ +K +Q+ + +Q +L +I
Sbjct: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 120 bits (301), Expect = 9e-27
Identities = 93/327 (28%), Positives = 174/327 (53%), Gaps = 43/327 (13%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQ-----------QEE 796
QQ +A+A L +E + + + + EE + L +QQEE + RQ QE+
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 797 ERKRREEEELARRKQEEALRRQR----EQEIALRRQRE-----EEERQQQEEALRRLEER 847
E K RE+EE R+QEE +RRQ E+E +RRQ E EE+ ++ EE + EE+
Sbjct: 320 EEKIREQEEKI-REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 907
RE EE+ ++E +R+QEE+ R+EEE ++ E R E+EA R EE+ R+++E
Sbjct: 379 IRELEEKMHEQEKIREQEEK-----RQEEE---KIREQEKRQEQEAKMWRQEEKIREQEE 430
Query: 908 LEVQRQKELMRQRQQ--QQEALRRLQQQQQQQQLAQMK---LPSSSTWGQQSNTTACQSQ 962
+++K++ RQ ++ +QE +R +++Q+Q+++ + + W Q+ Q
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK---MHEQ 487
Query: 963 ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKS 1022
+ E + +E + +EE+ R+Q E M +++ ++Q++K + + +
Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK------IREQEEKIRE 541
Query: 1023 LLEIQQEEARQMQKQQQQQQQHQQPNR 1049
E+ QE+ +M +Q+++ Q+ ++ R
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Score = 100 bits (249), Expect = 9e-21
Identities = 86/338 (25%), Positives = 175/338 (51%), Gaps = 40/338 (11%)
Query: 732 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 791
+L +T T E+ +L++ K +E E+ E ++ K + + +R + L QQ+
Sbjct: 208 ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 262
Query: 792 RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 850
Q E + +E + ++ + Q + E E+ R Q++EE+ +QEE ++ EE+ +E
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318
Query: 851 EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 892
+EE+ R+QEE +R+QEE E W +EE EE RRLEE EE+
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Query: 893 AARLRHE--EEERKRKELEVQRQKELMR--QRQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
L + E+E+ R++ E ++++E +R +++Q+QEA Q+++ ++Q +++
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438
Query: 949 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK---ALQQQQQQQQQ 1005
W Q+ + + E +K +E+ E +EE+ R+Q E+ + + +Q++ ++Q
Sbjct: 439 MWRQEEKIHEQE-----KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 1006 KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1043
+ W K + + E +++ RQ +K ++Q+++
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531
Score = 60.1 bits (144), Expect = 1e-08
Identities = 91/510 (17%), Positives = 204/510 (40%), Gaps = 80/510 (15%)
Query: 802 EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 835
E+E+ A + +EALRR+ E ++ R Q E E R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 836 --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 883
+ E+AL + ++++ EE K+ + L + E +E +L+
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 884 ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943
E +E E + ++ +E KRK ++R K L+ Q+Q Q EA ++ Q Q +
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 944 LPSSSTW---GQQSNTTACQSQATLSLAE--IQKLEE---ERERQLREEQRRQQRELMKA 995
+ + W QQ + + + E IQ+ EE E+E ++RE++ + +R+
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 996 LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ------QEEARQMQKQQQQQQQHQQPNR 1049
+++++ ++Q+ W K + + E + +E+ + +K ++Q+++ Q+ +
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 1050 ARNNTHSNLHTSIGNSVW-GSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVG 1108
R + +W + + +W + + + ++E
Sbjct: 405 IREQEKRQEQEA---KMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-----QEKIREEE 456
Query: 1109 PRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALN 1168
R + + RQ +K+ E+EK+ K + V + ++ E++
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
Query: 1169 TANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQ---- 1224
++ E E + IR E +E ++ E+ +Q+ Q
Sbjct: 517 -----------KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 1225 -RQQQQLPQQQQQQPPQQPPQQPQQQDSVW 1253
R+Q++ ++Q+++ +Q + +Q++ +W
Sbjct: 566 MRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/220 (24%), Positives = 98/220 (44%), Gaps = 65/220 (29%)
Query: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
DQE R+QE Q + ++ Q+ I++Q ++ Q++ + +Q++++ ++ Q
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE---MMQEQEEKMGEQEEKMQE 562
Query: 687 L-KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 745
KMR ++ I
Sbjct: 563 QEKMRRQEEKI------------------------------------------------- 573
Query: 746 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ----EEERKRR 801
+Q EK + K ++ RE E + +EE+ + QEE+ ++QEE + Q+ E+E K +
Sbjct: 574 -REQEEKIREQK--EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
Query: 802 EEEELARRKQEEALRRQREQEIALRRQREE-EERQQQEEA 840
E+EE RR++E + EQE+ LR+Q E+ +E Q+ EA
Sbjct: 631 EQEEKMRRQEE----KMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 42.7 bits (99), Expect = 0.002
Identities = 73/410 (17%), Positives = 162/410 (39%), Gaps = 49/410 (11%)
Query: 890 EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 949
+E+ A +H+E R+ E +V + L Q+ + Q AL Q +Q + L S
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 167
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 1002
S A + + LS QK + +R +L +E+ EL + L+++ +
Sbjct: 168 --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
Query: 1003 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
Q+KL + L+ + E A+ + QQQ Q + + + + L +
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1063 G-NSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1121
N +W +N + +W + W++ ++E + + K
Sbjct: 286 EENELWNRLNQQQEEK--------MWRQEEKIQE----WEEKIQEQEEKIREQEEKIREQ 333
Query: 1122 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1181
K RQ + + E+E+ ++ + + ++ + E+M+
Sbjct: 334 EEKM----RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK----------- 378
Query: 1182 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1241
++E+E + IR E ++ +Q E+R +Q+A RQ++++ +Q+++ Q+
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 1242 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q++ +H + + +Q E + +K ++Q+ +
Sbjct: 437 KKMWRQEE---------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Score = 37.4 bits (85), Expect = 0.096
Identities = 41/211 (19%), Positives = 86/211 (40%), Gaps = 12/211 (5%)
Query: 230 REEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERG 289
+EE+ E E WR + E+ R + WR+ E+ R E +R ++
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE-EKIREQEEIWRQKEKMHE 486
Query: 290 YRRVRSGSGSIDDDRDSL--PEWCLEDAEEEMGTFDSSGAFLSLK-KVQKEPIPEEQEMD 346
++R + + + E + + EE+M + K + Q+E I E++EM
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM- 545
Query: 347 FRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSD 406
+E + G E+ +E +K ++E + ++ E+ + + +
Sbjct: 546 ------MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 407 HQSQEASQFERKDEPKTEQTEK-AEEETRME 436
++ + ++E EQ EK E+E +M+
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
Score = 31.6 bits (70), Expect = 5.3
Identities = 37/188 (19%), Positives = 75/188 (39%), Gaps = 32/188 (17%)
Query: 214 RKHEFIRSESENWR----IFREEQNGEDEDGGWRLAGSRRDGER---------WRPHSPD 260
R+ E IR + E WR + +E+ + E+ WR D E WR
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 261 GPRSAGWREHMERRRRFEFDFRDRDDERGYR--------RVRSGSGSIDDDRDSLPEWCL 312
+ RE E+ R E ++++++ G + ++R I + + + E
Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585
Query: 313 EDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDK 372
+ E+E ++ Q+E I E++EM ++ E + E+ +E ++
Sbjct: 586 KIREQEEKIWE-----------QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Query: 373 TNKKEGEK 380
+++ EK
Sbjct: 635 KMRRQEEK 642
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 120 bits (301), Expect = 9e-27
Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 36/306 (11%)
Query: 762 RREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQRE 820
+R +R +E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ +
Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQ 579
Query: 821 QEIALRRQREEEERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEE 866
+ + +EE+++Q Q +E + +E R EE+ +K + E RKQEE
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 867 EA--AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 924
EA +W ++EEE +R E + + EEE RLR E ++ E Q ++E R+ Q+++
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
Query: 925 EALRRLQQ-QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLR 982
E RR Q+ ++Q++QLA+ Q+ + QA L E +K L ++E+ R
Sbjct: 700 EQERREQERREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQR 749
Query: 983 E-EQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
E E+++++ E + ++Q Q++Q+K + +G +K+L ++ Q
Sbjct: 750 ELEEKKKKEEQQRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTP 804
Query: 1042 QQHQQP 1047
Q H+ P
Sbjct: 805 QGHRAP 810
Score = 115 bits (288), Expect = 3e-25
Identities = 87/291 (29%), Positives = 157/291 (53%), Gaps = 32/291 (10%)
Query: 715 LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLE-KAKAAKLEQERREAEMRAKREE 773
+ PT++ +V + + PL ++L+ L K +A +L +++ E + R + EE
Sbjct: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEE 565
Query: 774 EERKRQEELRR--QQEEILRRQQEEERKRREE------EELARRKQEEALRRQREQEIAL 825
+ KR+E LR+ Q E + + +EE++K+ E+ E+ + K+E + +++ A
Sbjct: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
Query: 826 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN 885
++ E E R++QEE RRL ++EEEERR QE L +K+EE E+
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----------------EQE 669
Query: 886 RLRMEEEAARLRHE-EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 944
RLR EA RL + E+ER+ +E Q ++E R+ Q+++E R+L +Q+++++ Q +L
Sbjct: 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERL 727
Query: 945 PSSSTWGQQSNTTACQ-SQATLSLAEIQKLEEER---ERQLREEQRRQQRE 991
+ ++ Q Q L E +K EE++ ERQL+EEQ ++ +E
Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 81.6 bits (200), Expect = 4e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 750 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 805
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 717
Query: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 865
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 718 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
Query: 866 EEAAKWAREEEEA 878
E+ AK A +A
Sbjct: 773 EKKAKEAAGASKA 785
Score = 61.6 bits (148), Expect = 5e-09
Identities = 78/375 (20%), Positives = 163/375 (43%), Gaps = 70/375 (18%)
Query: 714 ELQPTAS-QPTVWE--GGSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM 767
E +P A+ +P V E G + W D + +TP P E A + E + +A+
Sbjct: 381 EAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK-PAASSPETPSAGQQEAKTDQAD- 438
Query: 768 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 827
RE + R+ +R ++ + EE+ EE + R K + + LR
Sbjct: 439 -GPREPPQSARR---KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
Query: 828 QREEEERQQQ------------EEALRRLEERRRE--EEERRKQEELLRKQEEEAAKWAR 873
+R Q + ++R R + E+ER++ E L RK+E E + +
Sbjct: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554
Query: 874 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 933
EE+ +RRLEE +L+ EER RK L+ + + E M++ +++Q + Q
Sbjct: 555 VEEDKRRRLEEVKLK-----------REERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
Query: 934 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE-- 991
++ ++ + +L AE + ++ +++ E + R+++E
Sbjct: 604 EKTEKAKEERL-----------------------AEEKAKKKAAAKKMEEVEARRKQEEE 640
Query: 992 --LMKALQQQQQQQ------QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1043
++ LQQ+++++ Q+K + + K L E +++E R+ ++++Q++++
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
Query: 1044 HQQPNRARNNTHSNL 1058
++ + R L
Sbjct: 701 QERREQERREQERQL 715
Score = 37.4 bits (85), Expect = 0.096
Identities = 75/390 (19%), Positives = 150/390 (38%), Gaps = 74/390 (18%)
Query: 477 PNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQD-SALDDERLAS 535
PNP P ETP G + D +G + Q A + +Y Q S LD+E+
Sbjct: 413 PNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE 467
Query: 536 --KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN--------NQEMAEWFQAGYFT 585
+LQ R+K S P P ++ P NQ + A
Sbjct: 468 DEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSV 515
Query: 586 MSLLVKRAC-------DESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELT 638
M +KR ++ Q L ++ + L++ +L R++ L
Sbjct: 516 MKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR 575
Query: 639 ALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQQQQLALLLQQFQTLK 688
+ Q Q + ++ I+Q++AQ+ A++++ A +++ A +++ + +
Sbjct: 576 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 635
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
+ + + + + + + + Q + + L E+ +
Sbjct: 636 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 695
Query: 749 QLEKAKAAKLEQERREAE--------------MRAKREEEERKR-----QEELRRQQEE- 788
Q E+ + + EQERRE E ++A+RE +ER++ +E+L+R+ EE
Sbjct: 696 Q-ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 789 --------ILRRQQEEERKRREEEELARRK 810
+ RQ +EE++++ +E K
Sbjct: 755 KKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
Score = 34.3 bits (77), Expect = 0.81
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 1199 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1257
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 1258 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1290
L + + +Q E + KK+++Q++
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
Score = 32.3 bits (72), Expect = 3.1
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 855 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 911
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
Query: 912 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
Query: 966 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 1008
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 116 bits (291), Expect = 1e-25
Identities = 93/295 (31%), Positives = 159/295 (53%), Gaps = 36/295 (12%)
Query: 773 EEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 831
E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ + + + +EE
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQARERVEQMKEE 594
Query: 832 EERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEEEA--AKWAREE 875
+++Q Q +E + +E R EE+ +K + E RKQEEEA +W ++E
Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654
Query: 876 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ-QQ 934
EE +R E + + EEE RLR E ++ E Q ++E R+ Q+++E RR Q+ ++
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714
Query: 935 QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLRE-EQRRQQREL 992
Q++QLA+ Q+ + QA L E +K L ++E+ RE E+++++ E
Sbjct: 715 QERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 764
Query: 993 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1047
+ ++Q Q++Q+K + +G +K+L ++ Q Q H+ P
Sbjct: 765 QRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAP 814
Score = 114 bits (284), Expect = 8e-25
Identities = 83/261 (31%), Positives = 147/261 (56%), Gaps = 33/261 (12%)
Query: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR--QQEEILRRQQEEERKRR 801
LE L++ E+A+ +L +++ E + R + EE + KR+E LR+ Q E + + +EE++K+
Sbjct: 542 LENLRRKEEAE--QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 599
Query: 802 EE------EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 855
E+ E+ + K+E + +++ A ++ E E R++QEE RRL ++EEEERR
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
Query: 856 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE-EEERKRKELEVQRQK 914
QE L +K+EE E+ RLR EA RL + E+ER+ +E Q ++
Sbjct: 660 HQELLQKKKEE----------------EQERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 915 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ-SQATLSLAEIQKL 973
E R+ Q+++E R+L +Q+++++ Q +L + ++ Q Q L E +K
Sbjct: 704 EQERREQERREQERQLAEQERRRE--QERLQAERELQEREKALRLQKEQLQRELEEKKKK 761
Query: 974 EEER---ERQLREEQRRQQRE 991
EE++ ERQL+EEQ ++ +E
Sbjct: 762 EEQQRLAERQLQEEQEKKAKE 782
Score = 104 bits (259), Expect = 6e-22
Identities = 71/203 (34%), Positives = 117/203 (57%), Gaps = 25/203 (12%)
Query: 743 ALEQLQQLEKAKAAKLEQ-------------ERREAEMRAKREEEERKRQE-ELRRQQEE 788
A E+++Q+++ K ++EQ E R AE +AK++ +K +E E RR+QEE
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Query: 789 ILRRQ---QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE 845
RR Q+EE +RR +E L ++K+EE R ++ E ++ E+ER++QE +
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 846 ERRREEEERRKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEEER 903
E+ R E+ERR+QE L +QE RE+E +A+R L+E + + +L+ E EE+
Sbjct: 704 EQERREQERREQERQLAEQERR-----REQERLQAERELQEREKALRLQKEQLQRELEEK 758
Query: 904 KRKELEVQRQKELMRQRQQQQEA 926
K+KE E QR E Q +Q+++A
Sbjct: 759 KKKE-EQQRLAERQLQEEQEKKA 780
Score = 100 bits (248), Expect = 1e-20
Identities = 67/182 (36%), Positives = 111/182 (60%), Gaps = 14/182 (7%)
Query: 735 LDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERK----RQEELRRQQEEIL 790
+D T E+L + EKAK ++ E E R K+EEE R+ +QEE R+ +E+L
Sbjct: 606 IDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 664
Query: 791 RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 850
++++EEE++R + A+R E+ + +REQE + +RE+E R+Q+ RR +ER+
Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE----RREQERQLA 720
Query: 851 EEERRKQEELLRKQEE--EAAKWAR-EEEEAQRRLEENRLRMEEE--AARLRHEEEERKR 905
E+ERR+++E L+ + E E K R ++E+ QR LEE + + E++ A R EE+E+K
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780
Query: 906 KE 907
KE
Sbjct: 781 KE 782
Score = 88.6 bits (218), Expect = 4e-17
Identities = 60/240 (25%), Positives = 136/240 (56%), Gaps = 28/240 (11%)
Query: 825 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK--WARE-----EEE 877
+ ++R+ E +++E +L ++ EE++RR+ EE+ K+EE K ARE +EE
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 594
Query: 878 AQRRLEENRLRMEEEAARLRHEE--EERKRKELEVQRQKELMRQRQQQQEA--LRRLQQQ 933
++++E+ +++E+ + + E EE+ +K+ ++ +E+ +R+Q++EA LR LQQ+
Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654
Query: 934 QQQ---QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 990
+++ Q+L Q K + + AE ++L E+RE++ RE++RR+Q
Sbjct: 655 EEERRHQELLQKKKEE-------------EQERLRKAAEAKRLAEQREQERREQERREQE 701
Query: 991 ELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ-EEARQMQKQQQQQQQHQQPNR 1049
+ ++Q++++Q++ + ++ E+Q+ E+A ++QK+Q Q++ ++ +
Sbjct: 702 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 761
Score = 81.6 bits (200), Expect = 4e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 750 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 805
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 664 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 721
Query: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 865
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 722 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 776
Query: 866 EEAAKWAREEEEA 878
E+ AK A +A
Sbjct: 777 EKKAKEAAGASKA 789
Score = 35.8 bits (81), Expect = 0.28
Identities = 75/394 (19%), Positives = 150/394 (38%), Gaps = 78/394 (19%)
Query: 477 PNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQD-SALDDERLAS 535
PNP P ETP G + D +G + Q A + +Y Q S LD+E+
Sbjct: 413 PNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE 467
Query: 536 --KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN--------NQEMAEWFQAGYFT 585
+LQ R+K S P P ++ P NQ + A
Sbjct: 468 DEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSV 515
Query: 586 MSLLVKRAC-----------DESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQ 634
M +KR ++ Q L ++ + L++ +L R+
Sbjct: 516 MKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 575
Query: 635 QELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQQQQLALLLQQF 684
+ L + Q Q + ++ I+Q++AQ+ A++++ A +++ A +++
Sbjct: 576 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 635
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
+ + + + + + + + + + Q + + L
Sbjct: 636 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 695
Query: 745 EQLQQLEKAKAAKLEQERREAE--------------MRAKREEEERKR-----QEELRRQ 785
E+ +Q E+ + + EQERRE E ++A+RE +ER++ +E+L+R+
Sbjct: 696 ERREQ-ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRE 754
Query: 786 QEE---------ILRRQQEEERKRREEEELARRK 810
EE + RQ +EE++++ +E K
Sbjct: 755 LEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788
Score = 34.3 bits (77), Expect = 0.81
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 1199 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1257
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Query: 1258 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1290
L + + +Q E + KK+++Q++
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 767
Score = 32.3 bits (72), Expect = 3.1
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 855 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 911
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
Query: 912 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
Query: 966 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 1008
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1368 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1427
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1487
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1488 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1714
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1715 LIRLRAETEQGEQQRQ 1730
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2182
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2183 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2233
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2234 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2349
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2470 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2514
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2573
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLL 2601
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1454
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1574
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1405
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1406 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1461
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1462 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1520
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1521 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1580
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1581 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1640
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1756
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1757 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2245 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2297
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2355
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2356 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2530
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2531 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2578 QQRRQ 2582
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1828
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1948
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1949 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2007
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1757
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1758 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1803
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2104 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2155 AALRQKQ 2161
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1864 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQK 2181
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1677 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1725
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1782
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1783 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1860 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1915
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1916 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1965
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2073
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2074 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2120
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2121 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2179
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1971 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2027
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2082
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2376
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2377 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2434
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2435 EIQRQQS 2441
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2388 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2447
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2448 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2507
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2508 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2567
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2568 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624
Query: 966 SL 967
+L
Sbjct: 2625 TL 2626
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2328 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2385
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2442
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2502
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2563 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2561 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2599
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2600 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2659
Query: 915 E 915
E
Sbjct: 2660 E 2660
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 631 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 690
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 691 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 750
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 751 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 795
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1372 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1431
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1432 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1491
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1492 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1550
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1551 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1610
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1611 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1670
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1671 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1718
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1719 LIRLRAETEQGEQQRQ 1734
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2067 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2126
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2127 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2186
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2187 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2237
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2238 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2296
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2297 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2353
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2354 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2413
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2414 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2473
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2474 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2518
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2519 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2577
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2578 QQLEQQRRQQEELLAEENQRLREQLQLL 2605
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1343 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1402
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1458
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1459 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1518
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1519 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1578
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1579 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1635
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1350 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1409
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1410 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1465
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1466 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1524
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1525 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1584
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1585 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1644
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1645 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1703
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1704 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1760
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1761 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1792
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2189 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2248
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2249 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2301
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2302 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2359
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2360 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2417
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2418 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2477
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2478 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2534
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2535 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2581
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2582 QQRRQ 2586
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1653 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1712
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1713 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1772
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1773 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1832
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1833 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1893 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1952
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1953 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2011
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2012 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2052
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1761
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1762 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1807
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1808 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1867
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1868 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1927
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1928 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1987
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1988 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2047
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2048 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2107
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2108 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2158
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2159 AALRQKQ 2165
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1868 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1924
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1925 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1984
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1985 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2044
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2045 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2104
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2105 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2164
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQK 2185
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1561 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1621 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1680
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1681 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1729
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1730 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1786
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1787 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1846
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1847 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1864 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1919
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1920 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1969
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1970 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2029
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2030 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2077
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2078 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2124
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2125 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2183
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2184 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2236
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1975 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2031
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2032 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2086
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2087 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2146
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2147 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2206
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2207 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2266
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2267 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2326
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2380
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2381 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2438
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2439 EIQRQQS 2445
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2392 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2451
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2452 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2511
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2512 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2571
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2572 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2628
Query: 966 SL 967
+L
Sbjct: 2629 TL 2630
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2332 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2389
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2390 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2446
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2447 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2506
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2507 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2566
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2567 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2618
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2505 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2564
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2565 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2603
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2604 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2663
Query: 915 E 915
E
Sbjct: 2664 E 2664
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 635 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 694
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 695 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 754
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 755 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 799
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1368 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1427
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1487
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1488 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1714
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1715 LIRLRAETEQGEQQRQ 1730
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2182
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2183 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2233
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2234 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2349
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2470 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2514
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2573
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLL 2601
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1454
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1574
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1405
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1406 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1461
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1462 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1520
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1521 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1580
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1581 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1640
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1756
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1757 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2245 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2297
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2355
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2356 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2530
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2531 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2578 QQRRQ 2582
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1828
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1948
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1949 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2007
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1757
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1758 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1803
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2104 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2155 AALRQKQ 2161
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1864 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQK 2181
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1677 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1725
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1782
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1783 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1860 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1915
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1916 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1965
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2073
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2074 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2120
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2121 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2179
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1971 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2027
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2082
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2376
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2377 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2434
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2435 EIQRQQS 2441
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2388 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2447
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2448 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2507
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2508 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2567
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2568 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624
Query: 966 SL 967
+L
Sbjct: 2625 TL 2626
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2328 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2385
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2442
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2502
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2563 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2561 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2599
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2600 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2659
Query: 915 E 915
E
Sbjct: 2660 E 2660
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 631 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 690
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 691 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 750
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 751 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 795
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1336 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1395
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1396 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1455
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1456 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1514
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1515 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1574
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1575 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1634
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1635 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1682
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1683 LIRLRAETEQGEQQRQ 1698
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2031 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2090
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2091 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2150
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2151 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2201
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2202 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2260
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2261 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2317
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2318 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2377
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2378 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2437
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2438 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2482
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2483 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2541
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2542 QQLEQQRRQQEELLAEENQRLREQLQLL 2569
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1307 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1366
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1422
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1423 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1482
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1483 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1542
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1543 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1599
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1314 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1373
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1374 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1429
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1430 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1488
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1489 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1548
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1549 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1608
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1609 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1667
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1668 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1724
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1725 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1756
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2153 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2212
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2213 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2265
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2266 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2323
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2324 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2381
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2382 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2441
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2442 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2498
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2499 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2545
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2546 QQRRQ 2550
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1617 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1676
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1677 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1736
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1737 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1796
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1797 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1856
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1857 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1916
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1917 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1975
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 1976 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2016
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1725
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1726 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1771
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1772 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1831
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1832 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1891
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1892 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1951
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1952 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2011
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2012 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2071
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2072 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2122
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2123 AALRQKQ 2129
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1832 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1888
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1889 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1948
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1949 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2008
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2009 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2068
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2069 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2128
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQK 2149
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1525 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1585 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1644
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1645 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1693
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1694 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1750
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1751 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1810
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1811 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1856
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1828 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1883
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1884 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1933
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1934 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 1993
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 1994 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2041
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2042 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2088
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2089 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2147
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2148 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2200
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1939 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 1995
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 1996 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2050
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2051 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2110
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2111 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2170
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2171 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2230
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2231 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2290
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2344
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2345 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2402
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2403 EIQRQQS 2409
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2356 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2415
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2416 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2475
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2476 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2535
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2536 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2592
Query: 966 SL 967
+L
Sbjct: 2593 TL 2594
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2296 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2353
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2354 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2410
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2411 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2470
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2471 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2530
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2531 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2582
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2469 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2528
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2529 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2567
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2568 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2627
Query: 915 E 915
E
Sbjct: 2628 E 2628
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 599 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 658
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 659 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 718
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 719 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 763
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1505 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1564
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1565 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1624
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1625 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1683
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1684 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1743
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1744 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1803
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1804 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1851
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1852 LIRLRAETEQGEQQRQ 1867
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2200 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2259
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2260 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2319
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2320 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2370
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2371 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2429
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2430 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2486
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2487 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2546
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2547 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2606
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2607 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2651
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2652 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2710
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2711 QQLEQQRRQQEELLAEENQRLREQLQLL 2738
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1535
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1591
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1592 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1651
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1652 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1711
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1712 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1768
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1483 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1542
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1543 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1598
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1599 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1657
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1658 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1717
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1718 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1777
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1778 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1836
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1837 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1893
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1894 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1925
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2322 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2381
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2382 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2434
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2435 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2492
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2493 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2550
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2551 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2610
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2611 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2667
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2668 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2714
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2715 QQRRQ 2719
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1786 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1845
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1846 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1905
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1906 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1965
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1966 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 2025
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 2026 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 2085
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 2086 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2144
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2145 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2185
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1894
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1895 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1940
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1941 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 2000
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 2001 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 2060
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 2061 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 2120
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 2121 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2180
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2181 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2240
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2241 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2291
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2292 AALRQKQ 2298
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 2001 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 2057
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 2058 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2117
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 2118 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2177
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2178 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2237
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2238 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2297
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2298 QAADAEMEKHKKFAEQTLRQK 2318
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1694 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1754 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1813
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1814 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1862
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1863 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1919
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1920 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1979
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1980 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 2025
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1997 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 2052
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 2053 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 2102
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 2103 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2162
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2163 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2210
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2211 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2257
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2258 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2316
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2317 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2369
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 2108 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2164
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2165 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2219
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2220 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2279
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2280 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2339
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2340 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2399
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2400 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2513
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2514 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2571
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2572 EIQRQQS 2578
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2525 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2584
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2585 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2644
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2645 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2704
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2705 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2761
Query: 966 SL 967
+L
Sbjct: 2762 TL 2763
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2465 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2522
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2523 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2579
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2580 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2639
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2640 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2699
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2700 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2751
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2638 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2697
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2698 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2736
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2737 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2796
Query: 915 E 915
E
Sbjct: 2797 E 2797
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 768 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 827
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 828 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 887
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 888 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 932
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1346 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1405
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1406 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1465
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1466 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1524
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1525 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1584
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1585 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1644
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1645 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1692
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1693 LIRLRAETEQGEQQRQ 1708
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2041 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2100
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2101 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2160
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2161 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2211
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2212 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2270
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2271 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2327
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2328 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2387
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2388 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2447
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2448 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2492
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2493 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2551
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2552 QQLEQQRRQQEELLAEENQRLREQLQLL 2579
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1317 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1376
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1377 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1432
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1433 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1492
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1493 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1552
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1553 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1609
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1324 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1383
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1384 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1439
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1440 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1498
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1499 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1558
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1559 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1618
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1619 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1677
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1678 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1734
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1735 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1766
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2163 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2222
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2223 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2275
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2276 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2333
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2334 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2391
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2392 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2451
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2452 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2508
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2509 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2555
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2556 QQRRQ 2560
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1627 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1686
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1687 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1746
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1747 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1806
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1807 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1866
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1867 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1926
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1927 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1985
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 1986 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2026
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1735
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1736 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1781
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1782 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1841
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1842 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1901
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1902 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1961
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1962 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2021
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2022 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2081
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2082 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2132
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2133 AALRQKQ 2139
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1842 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1898
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1899 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1958
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1959 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2018
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2019 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2078
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2079 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2138
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2139 QAADAEMEKHKKFAEQTLRQK 2159
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1535 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1595 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1654
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1655 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1703
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1704 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1760
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1761 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1820
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1821 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1866
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1838 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1893
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1894 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1943
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1944 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2003
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2004 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2051
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2052 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2098
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2099 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2157
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2158 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2210
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1949 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2005
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2006 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2060
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2061 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2120
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2121 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2180
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2181 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2240
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2241 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2300
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2354
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2355 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2412
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2413 EIQRQQS 2419
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2366 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2425
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2426 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2485
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2486 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2545
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2546 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2602
Query: 966 SL 967
+L
Sbjct: 2603 TL 2604
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2306 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2363
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2364 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2420
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2421 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2480
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2481 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2540
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2541 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2592
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2479 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2538
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2539 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2577
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2578 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2637
Query: 915 E 915
E
Sbjct: 2638 E 2638
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 609 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 668
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 669 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 728
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 729 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 773
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1354 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1413
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1414 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1473
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1474 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1532
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1533 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1592
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1593 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1652
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1653 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1700
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1701 LIRLRAETEQGEQQRQ 1716
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2049 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2108
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2109 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2168
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2169 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2219
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2220 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2278
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2279 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2335
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2336 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2395
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2396 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2455
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2456 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2500
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2501 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2559
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2560 QQLEQQRRQQEELLAEENQRLREQLQLL 2587
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1325 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1384
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1385 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1440
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1441 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1500
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1501 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1560
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1561 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1617
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1332 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1391
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1392 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1447
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1448 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1506
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1507 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1566
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1567 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1626
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1627 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1685
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1686 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1742
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1743 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1774
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2171 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2230
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2231 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2283
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2284 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2341
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2342 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2399
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2400 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2459
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2460 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2516
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2517 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2563
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2564 QQRRQ 2568
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1635 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1694
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1695 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1754
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1755 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1814
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1815 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1874
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1875 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1934
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1935 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1993
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 1994 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2034
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1743
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1744 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1789
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1790 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1849
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1850 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1909
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1910 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1969
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 1970 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2029
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2030 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2089
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2090 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2140
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2141 AALRQKQ 2147
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1850 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1906
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1907 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1966
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 1967 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2026
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2027 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2086
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2087 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2146
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2147 QAADAEMEKHKKFAEQTLRQK 2167
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1543 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1603 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1662
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1663 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1711
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1712 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1768
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1769 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1828
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1829 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1874
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1846 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1901
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1902 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1951
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1952 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2011
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2012 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2059
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2060 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2106
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2107 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2165
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2166 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2218
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1957 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2013
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2014 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2068
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2069 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2128
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2129 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2188
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2189 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2248
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2249 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2308
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2362
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2363 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2420
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2421 EIQRQQS 2427
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2374 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2433
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2434 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2493
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2494 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2553
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2554 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2610
Query: 966 SL 967
+L
Sbjct: 2611 TL 2612
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2314 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2371
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2372 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2428
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2429 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2488
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2489 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2548
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2549 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2600
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2487 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2546
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2547 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2585
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2586 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2645
Query: 915 E 915
E
Sbjct: 2646 E 2646
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 617 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 676
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 677 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 736
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 737 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 781
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 114 bits (286), Expect = 5e-25
Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 799
ALE+ +QL +A A Q REA+ +R +EE R+EE +QQ+ ++ + ++ R+
Sbjct: 1395 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1454
Query: 800 RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 833
E E A+ +Q EA R R E+EI ALR + EE E
Sbjct: 1455 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1514
Query: 834 --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 890
RQ QEEA RL + ++E +R++Q E+ L + + A+ ARE++ A + LEE RL+ E
Sbjct: 1515 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1573
Query: 891 EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 922
E RLR E ER R+ +LE Q+E + Q
Sbjct: 1574 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1633
Query: 923 QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
++EA RR QQQ + +++L + +L ++ + Q +L+ AE +K +
Sbjct: 1634 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1693
Query: 975 EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
EE ER+ R EEQ +QRE L +Q+ ++Q++L+ GT + L +QE
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1741
Query: 1030 EARQMQKQQQQQQQHQ 1045
R + +Q +QQ Q
Sbjct: 1742 LIRLRAETEQGEQQRQ 1757
Score = 110 bits (275), Expect = 9e-24
Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++LQQ + + + L+Q R EAE + EE + + + R+ + R+ +E ER ++ E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2149
Query: 805 ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
E A+ + + E LR++ EQE A R Q E+ +Q++ A +E+ ++ E+ +Q+
Sbjct: 2150 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2209
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
+ +QE + EE + Q+ L ++EE RL+ E E R+ +V ++EL
Sbjct: 2210 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2260
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 977
R Q +E L +L+ + + + A + +T Q A + +E R
Sbjct: 2261 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2319
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
RQL EE QQR L + + +++ Q Q+ + + + + E+ QE+AR++Q+
Sbjct: 2320 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2376
Query: 1038 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1089
++Q Q Q+ A + A +
Sbjct: 2377 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2436
Query: 1090 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1143
A+ + + A +E T + + S L +++ R+ +K+++E KLL
Sbjct: 2437 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2496
Query: 1144 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1203
+L K+++ T EQ+L SFL E +S + +I + +
Sbjct: 2497 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2541
Query: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1263
+ ++ + + + + + QQRQQQQ+ Q++Q+ + +Q ++ G+ +
Sbjct: 2542 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2600
Query: 1264 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1291
Q Q QQ A ++ + +++ +++
Sbjct: 2601 QQLEQQRRQQEELLAEENQRLREQLQLL 2628
Score = 103 bits (256), Expect = 1e-21
Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)
Query: 780 EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
E LRR +EE + +Q+ EER+R E E A KQ + + + R+ +E +++ Q
Sbjct: 1366 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1425
Query: 838 EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 892
EE +RR E ++++R QEEL LR+ E E AR+ E A+R +RLR+EEE
Sbjct: 1426 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1481
Query: 893 -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 943
RL+ E ER+R E E+Q R +E Q++Q QE RL Q Q + Q+ Q +
Sbjct: 1482 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1541
Query: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
+ +S ++ + +A +L E++ EE ER+LR+ + + R++ AL+ Q+
Sbjct: 1542 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1601
Query: 1004 QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ +L K + +SL E A+ ++ +++ QQ + RAR L
Sbjct: 1602 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1658
Score = 101 bits (251), Expect = 5e-21
Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)
Query: 627 DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
++ERL QQ E L +++ +Q + + +AQ AQ ++ A QQ+ Q ++ ++
Sbjct: 1373 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1432
Query: 684 FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 735
+ + Q S+ + S E+Q A Q E V L L
Sbjct: 1433 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1488
Query: 736 DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 783
+ T G A +LQ L +A+A + E ++R+A+ A+R +E +RKRQ E+
Sbjct: 1489 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1547
Query: 784 -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838
+ + E R +Q E R + EE RR ++ + R R+ ++AL + E + Q
Sbjct: 1548 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1607
Query: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 892
+ E+ + E +++ + + EEA + A+++ EA+R EE +E E
Sbjct: 1608 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1667
Query: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 949
A RLR + EE +++ Q + E ++ + ++EA RR + ++Q Q++LA+ +L
Sbjct: 1668 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1726
Query: 950 WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
+ + ++ L + + E++RQL EE+ R QRE A Q++Q+ + +
Sbjct: 1727 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1783
Query: 1009 GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1041
++K + LL + +EE+R ++ +Q+
Sbjct: 1784 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1815
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)
Query: 634 QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 688
+QELT L Q++ +Q+ L+ ++ ++ A+ +AA Q ++ + + +++ LK
Sbjct: 2212 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2271
Query: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
RI +N R++ + D + ++ L + L QL
Sbjct: 2272 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2324
Query: 749 QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 808
+ + A+ L ++ + +M+A +E K + EL +QQ+E+ Q++ R + ++E++A+
Sbjct: 2325 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2382
Query: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
+ EE QR E RQR+ E + E R+ E R + + + RKQ EE
Sbjct: 2383 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2440
Query: 869 AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 921
+ E A + LE R + + +A RLR E +R++ ++Q++ +L++ +
Sbjct: 2441 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2500
Query: 922 QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 981
++ + +++ Q Q+ Q L Q L + Q+ Q L ++ + E + +QL
Sbjct: 2501 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2557
Query: 982 REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
REEQ+RQQ QQ + V+ + E ++ R+ ++ QQ +
Sbjct: 2558 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 1042 QQHQQ 1046
QQ +Q
Sbjct: 2605 QQRRQ 2609
Score = 96.3 bits (238), Expect = 2e-19
Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 792
E++ Q + A+ E+++ EAE A+R EE+ RQ EL Q+ E R+
Sbjct: 1676 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1735
Query: 793 ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 823
+QE R R E EEELAR ++E A Q+ QE +
Sbjct: 1736 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1795
Query: 824 ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 849
A + + EEE R E++ +RLE R+R
Sbjct: 1796 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1855
Query: 850 EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 897
E ER E+L L+ + E A K E E RRL E+ R R+EE+AA+ +
Sbjct: 1856 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1915
Query: 898 HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 946
+ EE RK + E++RQK L +RQR+Q +E + L+ ++ A+++L
Sbjct: 1916 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1975
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+T + QA L A ++L E ER+ RE + R Q+ L A ++ +Q++
Sbjct: 1976 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2034
Query: 1007 LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1046
L + + L E +QE ARQ+Q Q+ Q+ Q
Sbjct: 2035 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2075
Score = 94.7 bits (234), Expect = 5e-19
Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)
Query: 628 QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686
Q+RL +QEL L + + + Q+ L++++ A++ Q++AA ++Q++Q+L + +
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1784
Query: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746
K+R + ++ S R+ + S + Q E G +L A E
Sbjct: 1785 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1830
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 803
+ A+ AK +++ E + +R E ER E+L E + + E + K E
Sbjct: 1831 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1890
Query: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 850
E L R ++EA +R+R +E A + + + EER Q + L R L +RR+
Sbjct: 1891 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1950
Query: 851 EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 880
EEE R E+ LR +E+ + AR+ EEE +R
Sbjct: 1951 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 2010
Query: 881 RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 927
R E R L EEEAAR R EE ER + ++E R ++E RQ Q QEA
Sbjct: 2011 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2070
Query: 928 -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+RLQ + QQ++Q Q L + Q A ++ AE +++ ERE
Sbjct: 2071 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2130
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Q R+Q E + L+Q ++Q Q + K E +QE AR+ Q +Q
Sbjct: 2131 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2181
Query: 1039 QQQQQHQ 1045
+Q Q
Sbjct: 2182 AALRQKQ 2188
Score = 90.5 bits (223), Expect = 1e-17
Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 798
E+L++L + +A Q RR E A+ + + +R +LR+ + L RQ+ +R
Sbjct: 1891 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1947
Query: 799 KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 851
++ EEE LA + E+A + E E+ L R R E Q + EA R+ + EE
Sbjct: 1948 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2007
Query: 852 EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 901
RR+ EE ++K EEEAA+ + E E + ++EE R R E+E+AR +
Sbjct: 2008 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2067
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
E +K L+ + + +Q++QE + LQQ+Q + + ++ +++ Q+
Sbjct: 2068 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2127
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
+ + + Q E ER +Q EEQ + + + A ++ +++ +Q+ + + + K
Sbjct: 2128 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2187
Query: 1022 SLLEIQQEEARQMQKQQQQQQ 1042
+ + E+ ++ +Q +Q+
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQK 2208
Score = 89.0 bits (219), Expect = 3e-17
Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)
Query: 744 LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 792
+E+ +Q++ A ++A+ E + + A K + ER QEE LR + E ++
Sbjct: 1584 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643
Query: 793 QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 847
Q E ER R E E R K EALR R + +E+A ++ + E +Q+EEA R R
Sbjct: 1644 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1703
Query: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 899
+ EE+ +Q EL A +E E QR+L E RL E+E RLR E
Sbjct: 1704 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1752
Query: 900 EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 958
E++R+ E E+ R Q+E Q++QE L + + + ++ L S + ++S +T+
Sbjct: 1753 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1809
Query: 959 CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 1010
+S+ L ++L EE R R L EE +RQ++ + +Q+ + + +KL+
Sbjct: 1810 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1869
Query: 1011 GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
G ++ + L + ++EA Q ++ ++Q QH+
Sbjct: 1870 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1915
Score = 89.0 bits (219), Expect = 3e-17
Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)
Query: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
E + ERL R E A +Q + L+ Q + + LAQ +KA+ S+ ++Q L+
Sbjct: 1887 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1942
Query: 685 QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 744
TL+ R + I ++ S G EL+ E G + DT
Sbjct: 1943 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1992
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 786
E ++ AA+ E+ RREAE R ++ EEE RQ EE RR +
Sbjct: 1993 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2052
Query: 787 EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
E L+ QE +KR + EE K +Q+EQE+ ++ QQE+
Sbjct: 2053 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2100
Query: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
++ L++ R E E R+ E E E A+ E E AQ R R EEA RL+
Sbjct: 2101 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2147
Query: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 956
EE+ + + Q E +R ++ +QEA RR Q +Q +Q+Q A ++ + +Q+
Sbjct: 2148 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2206
Query: 957 TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 1008
Q + L+ +Q E + ++ L +E+ +R + E +A +Q+ Q +++ S
Sbjct: 2207 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2259
Score = 79.3 bits (194), Expect = 2e-14
Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)
Query: 633 RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 690
RQ++L A + + + ++ +Q+ A + A+Q+KAAL ++ ++L +++ + L+ R
Sbjct: 1998 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2054
Query: 691 ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 742
++ + + + + + +Q Q T+ + SV D G
Sbjct: 2055 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2109
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 794
A + E+A+ A+++ ER A+ R + EE ER +Q + Q E LR++
Sbjct: 2110 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169
Query: 795 EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 836
E+E RR + E A +Q++A + Q EQE+ LR Q EE + Q+
Sbjct: 2170 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2229
Query: 837 Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 878
+E L+RL+ E +R Q EEL +R Q EE +K R+++
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2289
Query: 879 QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 912
QR L+E +M++ EAARLR EE K K VQ
Sbjct: 2290 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 913 -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 964
+ EL++Q+++ QE RRLQ+ ++Q QQLA+ T G Q A + +
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2403
Query: 965 LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
AE ++L + R ++ Q R + + + ++Q ++ +KL ++ T L
Sbjct: 2404 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2461
Query: 1025 EIQQEEA 1031
EIQ++++
Sbjct: 2462 EIQRQQS 2468
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)
Query: 746 QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
++ ++ +A+A E +R E+ K E QE++ Q ++RQQ + R
Sbjct: 2415 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2474
Query: 802 EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 848
E +A ++E+ +Q + + L+ + ++E+ Q+ +AL++ L+ R
Sbjct: 2475 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2534
Query: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 905
E+E+ K E+L + + +A + E++ Q+++E+ R R+ EEA R +HE EE R
Sbjct: 2535 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2594
Query: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
++ E +Q E Q+++QQE L + Q+ ++QL ++ + TA Q AT
Sbjct: 2595 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2651
Query: 966 SL 967
+L
Sbjct: 2652 TL 2653
Score = 68.9 bits (167), Expect = 3e-11
Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)
Query: 628 QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 687
+ L +QQ+ A Q + LQ + + QQ A+ Q+ L +++Q+QL + + + L
Sbjct: 2355 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2412
Query: 688 KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 741
K+R+++ + + + + G A+Q V V L +
Sbjct: 2413 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2469
Query: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E+L++ + E+ ++EA++ + EE + Q+E Q+ + L++ E+
Sbjct: 2470 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2529
Query: 802 EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 853
+ E +++ L + + E+A +Q REE++RQQQ+ R +EE RR + E
Sbjct: 2530 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2589
Query: 854 ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
RRKQEEL + +++ + EE QR E+ +L E+ A L H EE
Sbjct: 2590 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2641
Score = 63.9 bits (154), Expect = 1e-09
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)
Query: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
+L Q ++ + + AKLEQ ++ +A++ EE++RQ++ Q+ + L EE R+R+
Sbjct: 2528 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2587
Query: 803 E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
E EE RRKQEE Q+ E++R+QQEE L EE +R +E+L
Sbjct: 2588 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2626
Query: 862 RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 914
+E+ A A EE A + L R ++ AA E + R+++ QR +
Sbjct: 2627 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2686
Query: 915 E 915
E
Sbjct: 2687 E 2687
Score = 31.6 bits (70), Expect = 5.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)
Query: 871 WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 924
W E+EE + + N +E + L E E +++K E+Q + L+R+ +
Sbjct: 658 WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 717
Query: 925 EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 982
+ Q Q Q ++L + N Q + + AE +QKL+E R+
Sbjct: 718 PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 777
Query: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ L LQ Q +++Q G++S + K++++++
Sbjct: 778 CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 822
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 113 bits (282), Expect = 1e-24
Identities = 101/337 (29%), Positives = 166/337 (49%), Gaps = 50/337 (14%)
Query: 727 GGSVWDLPLDTTTP-------GPA-LEQLQQLEKAKAAKLEQERREAEMRAKREEEE--- 775
G S++ L T P GP+ +EQLQ +LE R+ + + +
Sbjct: 134 GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLL 193
Query: 776 RKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ 835
+RQEE R+QEE LR Q EER R +EE L +QEE LR Q E R RE+EER
Sbjct: 194 NRRQEERLREQEERLREQ--EERLREQEERLC--EQEERLREQEE------RLREQEERL 243
Query: 836 -QQEEALRRLEERRREEEER--------RKQEELLRKQEEEAAKWAREEEEAQRRLEENR 886
+QEE LR EER E+EER R+QEE L +QEE + E + RL E
Sbjct: 244 CEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQE 303
Query: 887 LRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 946
R+ E+ RL +EE + +E + Q++L Q + +E + L+Q+++Q++ ++
Sbjct: 304 ERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL--- 360
Query: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
+ L E+++L E+ ER ++++R Q+E ++ L++ ++ ++
Sbjct: 361 ---------------ERERLLEEVEELLEQ-ERLRQQDERLWQQETLQELERLRELERML 404
Query: 1007 LSGWGNVSKPSGTTKS-LLEIQQEEARQMQKQQQQQQ 1042
GW + + +S E+ E +Q +QQ ++
Sbjct: 405 ELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 441
Score = 106 bits (264), Expect = 2e-22
Identities = 93/274 (33%), Positives = 141/274 (51%), Gaps = 40/274 (14%)
Query: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----EER 798
L L + ++ + + E+ RE E R + +EE QEE R+QEE LR Q+E EER
Sbjct: 190 LSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEER 249
Query: 799 KRREEEELARRKQE--EALRRQREQEIALRRQRE-----EEERQQQEEALRRLEERRREE 851
R EE L +++ E R REQE L Q E EE ++QEE L EER RE+
Sbjct: 250 LREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQ 309
Query: 852 EERR-KQEELLRKQEE---EAAKWAREE---EEAQRRLEENRLRMEEEAARLRHEEEERK 904
EER +QEE LR+QEE E K +E EE ++ LE+ R + E+E R E ER
Sbjct: 310 EERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQE----RLLERERL 365
Query: 905 RKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
+E+E ++E +RQ+ + QQE L+ L++ ++ +++ ++ A
Sbjct: 366 LEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLEL------------GWEALYE 413
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKA 995
Q + ++L E + L+ EQ Q +EL K+
Sbjct: 414 QRAEPRSGFEELNNENKSTLQLEQ--QVKELKKS 445
Score = 99.0 bits (245), Expect = 3e-20
Identities = 74/261 (28%), Positives = 132/261 (50%), Gaps = 27/261 (10%)
Query: 793 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE 852
Q E R+E E + R+ Q E + Q ++L +R+EE ++QEE LR EER RE+E
Sbjct: 163 QDETNHLRKELESVGRQLQAEV---ENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219
Query: 853 ERR-KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
ER +QEE LR+QEE + E + RL E+ R+ E+ RL +EE + +E +
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279
Query: 912 RQKE-LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 970
Q+E L Q ++ +E RL +Q+++ + + +L ++ C+ + L
Sbjct: 280 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE---KLPGQ 336
Query: 971 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1030
++L EE E+ L +E+R++++E + ++ ++ ++ L +QE
Sbjct: 337 ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELL-------------------EQER 377
Query: 1031 ARQMQKQQQQQQQHQQPNRAR 1051
RQ ++ QQ+ Q+ R R
Sbjct: 378 LRQQDERLWQQETLQELERLR 398
Score = 47.8 bits (112), Expect = 7e-05
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 21/147 (14%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ---------E 795
EQ ++L + + EQE+ + R E E+ QE + +QE +L R++ E
Sbjct: 315 EQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLE 374
Query: 796 EERKRREEEELARRKQEEALRRQREQE-------IALRRQREE-----EERQQQEEALRR 843
+ER R+++E L +++ + L R RE E AL QR E EE + ++ +
Sbjct: 375 QERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ 434
Query: 844 LEERRREEEERRKQEELLRKQEEEAAK 870
LE++ +E ++ EE + AA+
Sbjct: 435 LEQQVKELKKSGGAEEPRGSESAAAAR 461
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 108 bits (270), Expect = 3e-23
Identities = 80/322 (24%), Positives = 158/322 (49%), Gaps = 16/322 (4%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++ ++ + K +++R R + +E ER+ E RQ+E+ RQ+E ER+ E
Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
Query: 805 ELARRKQEEALR---RQREQEIALRRQREEEERQQQE---EALRRLEERRREEEERRKQE 858
E R +Q + R RQR+ E RQ + E ++Q E + R E+ R+E ER +Q
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 859 ELLRKQEEEAAKWAREEE-------EAQRRLEENRLR-MEEEAARLRHEEEERKR-KELE 909
E K E+ ++ RE E E +R+ + +R R + + R R ++ ER+R E E
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 910 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 969
+R KE R+R + ++ RR +++++Q + + ++ + +
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
Query: 970 IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
++ E ERER+ RE QR +R+ K ++++++Q + + G ++ E ++E
Sbjct: 316 KRERERERERE-RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 1030 EARQMQKQQQQQQQHQQPNRAR 1051
R Q ++++++ + +R R
Sbjct: 375 RERDRQSAREREERERDRDRDR 396
Score = 105 bits (263), Expect = 2e-22
Identities = 78/320 (24%), Positives = 166/320 (51%), Gaps = 22/320 (6%)
Query: 741 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEE-----RKRQEELRRQQEEILRRQQE 795
G E+ +Q E+ + + Q RE + + +R E+ R R E +R +E+ RQ +
Sbjct: 51 GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD 110
Query: 796 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-EEER 854
ER R+ E+E R+K+ E R+ E+E R R+ + ++++E +ER R+ + ER
Sbjct: 111 RERDRQREKERNRQKERE---RETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER 167
Query: 855 RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 914
++Q E R++E E K +E E +R+ E+ + + R R E ER+ E E +R++
Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE-TETETERKR 226
Query: 915 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
+ R+R +Q++ R ++Q ++++ ++ + ++ + + + +
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD----------RDRDRRQ 276
Query: 975 EERERQL-REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1033
+ERERQ R+ QRR +R+ ++++Q+++++ + + E Q+E R
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336
Query: 1034 MQKQQQQQQQHQ-QPNRARN 1052
+K+++++++ Q + +R RN
Sbjct: 337 REKERERKRKRQTEMDRERN 356
Score = 104 bits (260), Expect = 5e-22
Identities = 74/324 (22%), Positives = 160/324 (49%), Gaps = 26/324 (8%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 807
++ E+ + A+ E+ER+ R ++ E R+++ E + ++E R+++ E++ + E+ +
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
Query: 808 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-----EEERRKQEELLR 862
R +E R+ E E +RQ + E +Q++ R ++ RE E ER K+ E R
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 863 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-----KELEVQRQKELM 917
++ + + +E E R + R + E R R + ER+R ++ E +R++E
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 918 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 977
R+RQ++ E R ++++++++ +M + G++ A + ++ E ER
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE---------RERERER 377
Query: 978 ERQLREEQRRQQRELMKALQQQQQQQQQK-LSGWGNVSKPSGTTKSL-LEIQQEEARQMQ 1035
+RQ E+ ++R+ + Q+++++Q +K G K K E +E R+ +
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 1036 KQQ-----QQQQQHQQPNRARNNT 1054
KQ+ +++Q +Q R R +
Sbjct: 438 KQKGRERDRERQTDRQAGRQRKRS 461
Score = 100 bits (249), Expect = 9e-21
Identities = 69/325 (21%), Positives = 155/325 (47%), Gaps = 15/325 (4%)
Query: 728 GSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR 784
G++W +PLD + P + E + L Q ++A+ ++ ER RQ+E R
Sbjct: 14 GTLWVEVTIPLDFSRRRPGSQ-----ESPRRRGLGQAHKDAD----GDDRERNRQKERER 64
Query: 785 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 844
++E+ ++ + ++ R E+ RK++ RQR++E RQ + E +Q+E+ R
Sbjct: 65 RREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQ 124
Query: 845 EERRREEE---ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
+ER RE E ER + + ++E E + A +E E Q E R E+
Sbjct: 125 KERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN 184
Query: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
++R+E E QR+KE + + + R ++++ + + + + Q+ +
Sbjct: 185 RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
Query: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
QA A ++ E ++ER+ ++ R + K ++Q +++Q+ + ++ +
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 1022 SLLEIQQEEARQMQKQQQQQQQHQQ 1046
E ++E R+ +++++++++ ++
Sbjct: 305 RERERERERNRKRERERERERERER 329
Score = 93.2 bits (230), Expect = 1e-18
Identities = 63/264 (23%), Positives = 124/264 (46%), Gaps = 22/264 (8%)
Query: 759 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ 818
+++R+ R K+ E ER + E R +E R ++ +R RR++E + ++ R +
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 819 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 878
R++E +R+R+ E +++E +R ER RE E R++E +++E K R+ E
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 879 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 938
+ R + +A R R E ER R+ + ++E R R +Q+E R+ ++ + Q+
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 939 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 998
+++ + ++ E RER RE ++++ RE + Q
Sbjct: 413 ---------------------ETEKQREREKDRESERGRERG-REREKQKGRERDRERQT 450
Query: 999 QQQQQQQKLSGWGNVSKPSGTTKS 1022
+Q +Q+ V+ P T +S
Sbjct: 451 DRQAGRQRKRSTLYVNPPPRTARS 474
Score = 87.8 bits (216), Expect = 6e-17
Identities = 67/219 (30%), Positives = 118/219 (53%), Gaps = 20/219 (9%)
Query: 745 EQLQQLEKAKAAKLEQER-------REAEMRAKREEEERKRQEELRRQQEEILRRQQEEE 797
E+ +Q E+ +A++ E ER R+ + R ++ER+RQ + +RQ+ R+ E +
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
Query: 798 RKRREEEELAR-----RKQEEALRRQREQEIALRRQREEE-ERQQQEEALRRLEERRREE 851
R+R+ E E R R++E R+RE++ R RE+E ER+++ + E R+
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 852 EERRKQEELLRKQEEEAAKW-AREEEEAQR-----RLEENRLRMEEEAARLRHEEEERKR 905
E R+Q E R++E E + ARE EE +R R +E + E++ R E++R+R
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
Query: 906 -KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943
K+ E +R +E R+R++Q+ R ++Q +Q Q K
Sbjct: 421 EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 76.3 bits (186), Expect = 2e-13
Identities = 63/227 (27%), Positives = 102/227 (44%), Gaps = 23/227 (10%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR----QQEEILRRQQEEERKR 800
E ++ E+ + + E+ER R + E ER+RQ E R ++E +RQ E +R+R
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
Query: 801 -REEEELARRKQEEALRRQREQEIALRRQREEEE----RQQQEEALRRLEERRREEEERR 855
R+ RR+ E R+RE++ R+REE E R +Q+E R+ E+ R + E
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
Query: 856 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 915
KQ E + +E E + E E Q+ E +R R + R +RKR L V
Sbjct: 416 KQREREKDRESERGRERGREREKQKGRERDRERQTD-----RQAGRQRKRSTLYVNPPPR 470
Query: 916 LMRQRQQQQEALR-----RLQQQQQQQQLAQMKLPSSSTWGQQSNTT 957
R Q + R R + + + A + P WG+ + +
Sbjct: 471 TARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFP----WGRPAKAS 513
Score = 47.4 bits (111), Expect = 9e-05
Identities = 69/321 (21%), Positives = 120/321 (37%), Gaps = 28/321 (8%)
Query: 117 PRGRSSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERG-DRRFEKPGRK 175
P + S R RG G+ + D + R RE R + ER DR+ E+ K
Sbjct: 31 PGSQESPRRRGLGQAH-----KDADGDDRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 176 DVGKKNGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNG 235
D +K + + + + E+ R+ + R + N + +E+
Sbjct: 86 DRHRKRDRHR-------------ERQRDREKERERQTDRERDRQREKERNRQ---KERER 129
Query: 236 EDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRS 295
E E G R + DG+R R D + + ER+R+ E R+R ER R ++
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE---RNRQKER--EREKN 184
Query: 296 GSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEE 355
+ +R E ED E G + +K E++ + E E+
Sbjct: 185 RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
Query: 356 CSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQF 415
++ E + E + + ++ DR E QT R T D +++ +
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR-RTERDRETERKRER 303
Query: 416 ERKDEPKTEQTEKAEEETRME 436
+R+ E + E+ K E E E
Sbjct: 304 QRERERERERNRKRERERERE 324
Score = 35.0 bits (79), Expect = 0.48
Identities = 54/253 (21%), Positives = 88/253 (34%), Gaps = 18/253 (7%)
Query: 210 TSVGRKHEFIRSESENWRIFRE-EQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWR 268
T RK + R + RE E+ E E R ++ ER R D R R
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Query: 269 EHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAF 328
E R+R RDR+ ER R R + +R E E E +
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 329 LSLKKVQKEPIPEEQEMDFRPVDEG----------EECSDSEGSHNEEAKEPDKTNKKEG 378
+K +K ++E + + EG E D + + E +E D+ ++
Sbjct: 340 ERERK-RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398
Query: 379 EKT-----DRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEET 433
E+ DR G E Q R + +E + + ++ + QT++
Sbjct: 399 ERERQTEKDRDGQRETEK-QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
Query: 434 RMENSLPAKVPSR 446
R ++L P R
Sbjct: 458 RKRSTLYVNPPPR 470
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 106 bits (264), Expect = 2e-22
Identities = 74/184 (40%), Positives = 109/184 (59%), Gaps = 15/184 (8%)
Query: 757 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 816
+L+QE +E +R++ QE+ R+QEE R+ E +KR E+++ RR+ EE R
Sbjct: 358 RLQQENKERSEALRRQQ---LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR 414
Query: 817 RQREQEIALRRQREEEERQQQEEALRRLEE---RRREEEERRKQEELLRKQEEEAAKWAR 873
R+RE RRQ+E E+R++++E RRLEE RR+EEEERR+ EE R+ E E R
Sbjct: 415 REREA----RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRR 470
Query: 874 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQEALRRLQQ 932
+ EE QR LE + ++ +E A L E + +E+E RQ E L RQ QQ+Q L LQ
Sbjct: 471 QLEEEQRHLEVLQQQLLQEQAMLL----ECRWREMEEHRQAERLQRQLQQEQAYLLSLQH 526
Query: 933 QQQQ 936
++
Sbjct: 527 DHRR 530
Score = 98.2 bits (243), Expect = 5e-20
Identities = 71/220 (32%), Positives = 114/220 (51%), Gaps = 26/220 (11%)
Query: 750 LEKAKAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRRQ----QEEERK 799
+++ + + E++ E E EEEE ++E + E LRR Q+E ++
Sbjct: 306 IDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE 365
Query: 800 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
R E + QE+ LR Q E + L +R++ QQ+E+ R E++RRE E RR+QE
Sbjct: 366 RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQER 425
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
R++E+E K EE E +R+ EE R R EEE R+ E+E +R+ E QR E+++Q
Sbjct: 426 EQRRREQE-EKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ 484
Query: 920 RQQQQEAL---------------RRLQQQQQQQQLAQMKL 944
+ Q++A+ RLQ+Q QQ+Q + L
Sbjct: 485 QLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSL 524
Score = 89.0 bits (219), Expect = 3e-17
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 57/305 (18%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKRE-EEERKRQEELRRQQEEILRRQQEEERKRREEEE- 805
+QL K + + R+ ++ K + RK++ E + E ++EEE +E E
Sbjct: 281 EQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEP 340
Query: 806 --LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 863
+ E LRR LR Q+E +ER EALRR ++ +E++ R+QEE R+
Sbjct: 341 SSIVNVPGESTLRRD-----FLRLQQENKERS---EALRR--QQLLQEQQLREQEEYKRQ 390
Query: 864 QEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 923
E K +++E +RRLEE + R E AR + E E+R+R++ E +R +EL R+R+++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRR--EREARRQQEREQRRREQEEKRRLEELERRRKEE 448
Query: 924 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE 983
+E RR ++++++ +++ +E RQL E
Sbjct: 449 EER-RRAEEEKRR---------------------------------VEREQEYIRRQLEE 474
Query: 984 EQRRQQRELMKALQQQQQQQQQKL--SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
EQR ++ LQQQ Q+Q L W + + + ++QQE+A + Q +
Sbjct: 475 EQRH-----LEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHR 529
Query: 1042 QQHQQ 1046
+ H Q
Sbjct: 530 RPHPQ 534
Score = 87.0 bits (214), Expect = 1e-16
Identities = 50/126 (39%), Positives = 83/126 (65%), Gaps = 4/126 (3%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
++++Q ++ + EQ+RRE E R ++E E+R+R++E +R+ EE+ RR++EEE +RR EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 805 ELAR-RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 863
E R +++E +RRQ E+E +R E ++Q +E LE R RE EE R+ E L R+
Sbjct: 457 EKRRVEREQEYIRRQLEEE---QRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQ 513
Query: 864 QEEEAA 869
++E A
Sbjct: 514 LQQEQA 519
Score = 81.3 bits (199), Expect = 6e-15
Identities = 61/191 (31%), Positives = 113/191 (59%), Gaps = 21/191 (10%)
Query: 743 ALEQLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798
AL + Q L++ + + E+ +R E + R ++++E+R+R EE +R++ E RRQQE E+
Sbjct: 369 ALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA-RRQQEREQ 427
Query: 799 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 858
+RRE+EE +R+ EE RR++E+E RR+ EEE+R+ + E E RR+ EE ++
Sbjct: 428 RRREQEE--KRRLEELERRRKEEEE--RRRAEEEKRRVEREQ----EYIRRQLEEEQRHL 479
Query: 859 ELLRKQ--EEEA----AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 912
E+L++Q +E+A +W E E R+ E + ++++E A L + + +R + +
Sbjct: 480 EVLQQQLLQEQAMLLECRW--REMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQ 537
Query: 913 QKELMRQRQQQ 923
Q +Q + +
Sbjct: 538 QPPPPQQERSK 548
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 105 bits (263), Expect = 2e-22
Identities = 76/307 (24%), Positives = 168/307 (54%), Gaps = 54/307 (17%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEER-----KRQEELRRQQEEILRRQQEEERK 799
+QL QL++ K + + + E++ ++++ + Q+ L++QQE++ +Q +E++
Sbjct: 128 QQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQV 187
Query: 800 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
+++E+L ++ QE+ L +Q+++++ ++++ QQ+E L++ + ++++E+ +++Q+
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQL------QQQQLLQQQEQLQQQQFQQQQEQLQQQQQL 241
Query: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
LL +Q+ + + ++++AQ + +L +++ + +++L +Q+Q++L Q
Sbjct: 242 LLLQQQGQLQQQLLQQQQAQLQ------------QQLLEQQQAQLQQQLLLQQQEQL--Q 287
Query: 920 RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERER 979
+QQQQ+ L++ Q+Q QQQQL L + + L L + E+
Sbjct: 288 QQQQQQLLQQQQEQLQQQQLQPPPLEPEE-----------EEEVELELMPVDLGSEQELE 336
Query: 980 QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQ 1039
Q R+E RQQ L++QQ+Q+Q +L K E+QQ E + Q+QQQ
Sbjct: 337 QQRQELERQQE-----LERQQEQRQLQL-------------KLQEELQQLEQQLEQQQQQ 378
Query: 1040 QQQQHQQ 1046
+QQ Q
Sbjct: 379 LEQQEVQ 385
Score = 105 bits (262), Expect = 3e-22
Identities = 78/328 (23%), Positives = 175/328 (53%), Gaps = 43/328 (13%)
Query: 736 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 795
+ T PG QLQQLE+ + E +++ + E+L++ Q + +QQ
Sbjct: 80 EETRPGQRELQLQQLEQ-----------------QPEPQQQPQHEQLQQPQPHLELQQQP 122
Query: 796 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 855
++ +++ +L + K + ++ + E+ L Q+++ + QQ +E +RL++++ + + ++
Sbjct: 123 QQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQ-QRLQQQQEQLQTQQ 181
Query: 856 KQEELLRKQEEEAAKWAREEE---EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 912
QE+ + +Q+E+ + +E++ + Q +L++ +L ++E +L+ ++ ++++++L+ Q+
Sbjct: 182 AQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE--QLQQQQFQQQQEQLQQQQ 239
Query: 913 QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK 972
Q L++Q+ Q Q+ L + QQ Q QQQL + + Q Q Q L + Q+
Sbjct: 240 QLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ------AQLQQQLLLQQQEQLQQQQQQQ 293
Query: 973 LEEERERQLR-----------EEQRRQQRELMKA---LQQQQQQQQQKLSGWGNVSKPSG 1018
L ++++ QL+ EE+ + ELM +Q+ +QQ+Q+L + +
Sbjct: 294 LLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQE 353
Query: 1019 TTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046
+ L++Q+E + Q+ +QQQQQ +Q
Sbjct: 354 QRQLQLKLQEELQQLEQQLEQQQQQLEQ 381
Score = 97.8 bits (242), Expect = 6e-20
Identities = 100/414 (24%), Positives = 206/414 (49%), Gaps = 89/414 (21%)
Query: 612 PFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQ-QYAQVLAQQQKAALS 670
P P + P E+ +E Q+EL Q+Q L+ Q QQ Q+ Q+ Q L
Sbjct: 64 PQRPAVSAPVGASEIAEETRPGQREL----QLQQLEQQPEPQQQPQHEQLQQPQPHLELQ 119
Query: 671 SQQQQQLALLLQQFQTLKMR-ISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS 729
Q QQ L Q Q K + + Q + P ELQ Q
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKP---------------ELQLMHQQ-------- 156
Query: 730 VWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ--QE 787
+QLQ + + +L+Q++ + + + +E++ ++QE+L++Q ++
Sbjct: 157 ---------------QQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQ 201
Query: 788 EILRRQQEEERKRR---EEEELARRK-QEEALRRQREQEIALRRQREEEERQQQEEALRR 843
++L++QQE+ ++++ ++E+L +++ Q++ + Q++Q++ L +Q+ + ++Q ++ +
Sbjct: 202 QLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ 261
Query: 844 LEERRREEEERRKQEELLRKQEEEAAKWAREE--EEAQRRLEENRLRM------EEEAAR 895
L+++ E+++ + Q++LL +Q+E+ + +++ ++ Q +L++ +L+ EEE
Sbjct: 262 LQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVE 321
Query: 896 LR------HEEEERKRKELEVQRQKELMRQRQQQQ------EALRRLQQQ--QQQQQLAQ 941
L E+E +++ E++RQ+EL RQ++Q+Q E L++L+QQ QQQQQL Q
Sbjct: 322 LELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQ 381
Query: 942 MKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKA 995
++ Q L+ E+ ++E + +L Q Q EL+ A
Sbjct: 382 QEV-----------------QLELTPVELGAQQQEVQLELTPVQPELQLELVPA 418
Score = 95.1 bits (235), Expect = 4e-19
Identities = 85/320 (26%), Positives = 160/320 (50%), Gaps = 57/320 (17%)
Query: 736 DTTTPGPALEQLQQLEKAKAAKLEQERREAEM---RAKREEEERKRQEELRRQQEEILRR 792
DT + G + Q+ E+ + +R ++ EE R Q EL+ QQ E
Sbjct: 40 DTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLE---- 95
Query: 793 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE 852
QQ E +++ + E+L + + L++Q +Q+ QQQ L++ + + +
Sbjct: 96 QQPEPQQQPQHEQLQQPQPHLELQQQPQQD-----------GQQQLSQLQQEKHQSVHHQ 144
Query: 853 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE--ERKRKELEV 910
E + + +L+ +Q++ + +E++ Q++ E+ + + +E L+ +E+ ++ +++ +
Sbjct: 145 ELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLL 204
Query: 911 QRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968
Q+Q+E ++Q+Q QQQE L++ Q QQQQ+QL Q Q Q Q L
Sbjct: 205 QQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ-----------QQQLLLLQQQGQLQQQ 253
Query: 969 EIQKLEEERERQLREEQRRQ-QRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
+Q+ + + ++QL E+Q+ Q Q++L+ LQQQ+Q QQQ Q
Sbjct: 254 LLQQQQAQLQQQLLEQQQAQLQQQLL--LQQQEQLQQQ---------------------Q 290
Query: 1028 QEEARQMQKQQQQQQQHQQP 1047
Q++ Q Q++Q QQQQ Q P
Sbjct: 291 QQQLLQQQQEQLQQQQLQPP 310
Score = 79.7 bits (195), Expect = 2e-14
Identities = 69/284 (24%), Positives = 139/284 (48%), Gaps = 50/284 (17%)
Query: 784 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 843
+++EE R +R A EE QRE ++ Q+ E ++Q Q E L++
Sbjct: 52 QEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQ 111
Query: 844 ----LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE--EAARLR 897
LE +++ +++ ++Q L++++ ++ + E Q ++ +L+ ++ E RL+
Sbjct: 112 PQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQ 171
Query: 898 HEEEE---RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQS 954
++E+ ++ +E +V +Q+E ++Q+ Q+Q+ L++ Q+Q QQQQL Q +
Sbjct: 172 QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ----------- 220
Query: 955 NTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVS 1014
++L++++ +Q +E+ ++QQ+ L+ LQQQ Q QQQ L
Sbjct: 221 ----------------EQLQQQQFQQQQEQLQQQQQLLL--LQQQGQLQQQLLQ------ 256
Query: 1015 KPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1058
+ ++QQ+ Q Q Q QQQ QQ + + L
Sbjct: 257 ------QQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Score = 37.7 bits (86), Expect = 0.073
Identities = 19/39 (48%), Positives = 28/39 (71%), Gaps = 4/39 (10%)
Query: 1218 KQKANQQRQQQQLPQQQQQQPPQQ----PPQQPQQQDSV 1252
+Q+ QQ+QQQQL QQQQ+Q QQ PP +P++++ V
Sbjct: 282 QQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEV 320
Score = 36.6 bits (83), Expect = 0.16
Identities = 66/339 (19%), Positives = 136/339 (40%), Gaps = 33/339 (9%)
Query: 980 QLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
++ EE R QREL ++ L+QQ + QQQ +P LE+QQ Q Q+
Sbjct: 77 EIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPH------LELQQ----QPQQDG 126
Query: 1039 QQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMG 1098
QQQ Q + ++ H L + + P + T+ +
Sbjct: 127 QQQLSQLQQEKHQSVHHQELKPEL-QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ-- 183
Query: 1099 FWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQ 1158
+ + + + L + +Q + ++++E+L + Q + Q+ Q
Sbjct: 184 ----EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ--QQFQQQQEQLQQ 237
Query: 1159 WCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAK 1218
+Q L L L ++ + ++ + +A L ++ Q E+ +
Sbjct: 238 --QQQLLLLQQQGQLQQQLLQQ--QQAQLQQQLLEQQQAQL-----QQQLLLQQQEQLQQ 288
Query: 1219 QKANQ--QRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNF 1276
Q+ Q Q+QQ+QL QQQ Q PP +P ++ + + + ++ + + Q Q +Q
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348
Query: 1277 EAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIE 1315
E Q ++++ Q ++ + L + ++L E++
Sbjct: 349 ERQQ--EQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQ 385
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 104 bits (260), Expect = 5e-22
Identities = 81/327 (24%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR--- 800
LE+ + ++ + ++E+ERRE E +RE E R+R+ E R++E +++E ER+R
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350
Query: 801 ----------REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 850
R+ E R +E + R +++ + + R+ E +++E R ER RE
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410
Query: 851 EEERRKQEELLRKQEEEAAKWAREEEEA---QRRLEENRLRMEEEA--ARLRHEE--EER 903
E R++E ++ E+ K REE+E +RR E +LR +E A RL++ E E +
Sbjct: 411 REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470
Query: 904 KRKELEVQRQKELMRQRQQQQEALRR---LQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 960
K +E E + ++E R+R+ +EA R L+ + + S+ + +
Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530
Query: 961 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 1020
+ E ++LEE R+R L E EL + Q+ ++++Q + + + +
Sbjct: 531 ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ------IKQEPESE 584
Query: 1021 KSLLEIQQEEARQMQKQQQQQQQHQQP 1047
+ E Q++E ++ + +++++ Q+P
Sbjct: 585 EEEEEKQEKEEKREEPMEEEEEPEQKP 611
Score = 99.8 bits (247), Expect = 2e-20
Identities = 76/308 (24%), Positives = 158/308 (51%), Gaps = 20/308 (6%)
Query: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREEEEL 806
++LE+ K K E+ER+E E + E ER+R+ E R R++E R++E+E++R E E
Sbjct: 289 KKLEEEKGKK-EKERQEIEKERRERERERERERERREREREREREREREKEKERERERER 347
Query: 807 AR---RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-EEERRKQEELLR 862
R R +E R RE++ R+R + + + + + +R RE E ER ++ E R
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 407
Query: 863 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL----MR 918
++E E + E E +R ++ R R E+E + ERK +E E Q+ L +R
Sbjct: 408 EREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Query: 919 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
+R++ +E + ++++++++ + + + + + A +QK +RE
Sbjct: 468 ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSA-LQKRLRDRE 526
Query: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
+++ ++R ++RE +++ ++ +Q+L G+ + L ++QE R+ Q Q
Sbjct: 527 KEMEADERDRKRE-----KEELEEIRQRLLAEGHPDPDA----ELQRMEQEAERRRQPQI 577
Query: 1039 QQQQQHQQ 1046
+Q+ + ++
Sbjct: 578 KQEPESEE 585
Score = 96.3 bits (238), Expect = 2e-19
Identities = 91/353 (25%), Positives = 150/353 (42%), Gaps = 71/353 (20%)
Query: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR---R 801
E+ ++ EK K + E+ER R K + +R R+ + R +E R ++ R R R
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 802 EEEELARRKQEEALRRQREQEIALRRQREEE-ERQQQEEALRRLEERRREEEERRKQEEL 860
+ E R++E R+RE+E R+RE E ER+++++ R EE + ERRK E
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449
Query: 861 LRKQE----EEAAKW-------AREEEEAQRRLEENRLRMEEEAARLRH----------- 898
LR++E E W RE E+ R EE R M +EA RL+
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509
Query: 899 ----------------------EEEERKRK--ELEVQRQKELMRQRQQQQEALRRLQQQQ 934
+E +RKR+ ELE RQ+ L L+R++Q+
Sbjct: 510 PKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEA 569
Query: 935 QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 994
++++ Q+K S ++ E Q+ EE+RE + EE+ +Q+ +K
Sbjct: 570 ERRRQPQIKQEPESEEEEE---------------EKQEKEEKREEPMEEEEEPEQKPCLK 614
Query: 995 ALQQQQQQQQQKLSGWGNV--SKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1045
+ S GN + P + + I E + QQQ ++H+
Sbjct: 615 PTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENS----PDQQQPEEHR 663
Score = 90.1 bits (222), Expect = 1e-17
Identities = 78/332 (23%), Positives = 159/332 (47%), Gaps = 53/332 (15%)
Query: 751 EKAKAAKLEQERREAEMRA---------KREEEERKRQEELRRQQEEILRRQQEEERKRR 801
E A ++E+++R+ R K EEE+ K+++E + ++E R++E ER+R
Sbjct: 262 EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERE 321
Query: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
RR++E R+RE+E R+RE E + ++ R +R RE + R +E
Sbjct: 322 ------RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS 375
Query: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-KELEVQRQKELMRQR 920
+ ++ + +RE+ + R E E E R R E ER+R +E E +R+K+ R R
Sbjct: 376 DRNKDRSR--SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR 433
Query: 921 QQQQE---ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 977
++ +E R+L+++ ++++ A + + ++ T + +A + EEER
Sbjct: 434 EEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEA--------EREEER 485
Query: 978 ERQLREEQRRQQRELM--------------KALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1023
R++ +E +R + L ALQ++ + +++++ K + L
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKRE--KEEL 543
Query: 1024 LEIQQ--------EEARQMQKQQQQQQQHQQP 1047
EI+Q + ++Q+ +Q+ ++ +QP
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Score = 75.5 bits (184), Expect = 3e-13
Identities = 57/315 (18%), Positives = 152/315 (48%), Gaps = 49/315 (15%)
Query: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ-------------QEEILRRQ 793
++ L + +++L +E++ +++++E+K E++ R+ +E+I +
Sbjct: 211 IEVLIREYSSELNAPSQESDSHPRKKKKEKK--EDIFRRFPVAPLIPYPLITKEDINAIE 268
Query: 794 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE-- 851
EE+++ E+++ + + + + RQ E+ER+++E R ERR E
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328
Query: 852 ----EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 907
ER K++E R++E + + +E + R E +R R E ++ + + K
Sbjct: 329 REREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKS 388
Query: 908 LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 967
+ +R++E R+R++++E R ++++++++ + +
Sbjct: 389 RDRERERERERERERERERERERERERERERERERE------------------------ 424
Query: 968 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
++ +++R+R+ EE ++R+L + L++++ Q++L W + + T + E +
Sbjct: 425 ---REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNW-EIRERKKTREYEKEAE 480
Query: 1028 QEEARQMQKQQQQQQ 1042
+EE R+ + ++ ++
Sbjct: 481 REEERRREMAKEAKR 495
Score = 46.2 bits (108), Expect = 2e-04
Identities = 61/315 (19%), Positives = 142/315 (45%), Gaps = 60/315 (19%)
Query: 744 LEQLQQLEKAKAAKLEQERREA--EMRAKREEEE-RKRQEELRRQQEEILRRQQEEERKR 800
L LQ EK K++ + + E +AK++ R E + EE L +EE KR
Sbjct: 147 LHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEAL----DEETKR 202
Query: 801 REE------EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 854
R++ E L R E +E + R++++E++ E+ RR
Sbjct: 203 RDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKK----EDIFRRFPVAPLIPYPL 258
Query: 855 RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 914
+E++ + EE + E ++ R + ++EEE + +E++R+E+E +R++
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFR--DTHKKLEEEKGK-----KEKERQEIEKERRE 311
Query: 915 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
R+R++++E RR ++++++++ + K E
Sbjct: 312 ---RERERERERERREREREREREREREK------------------------------E 338
Query: 975 EERERQL---REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1031
+ERER+ R+ R ++R+ + ++ + + +++ S S E ++E
Sbjct: 339 KERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
Query: 1032 RQMQKQQQQQQQHQQ 1046
R+ +++++++++ ++
Sbjct: 399 RERERERERERERER 413
Score = 41.2 bits (95), Expect = 0.007
Identities = 70/354 (19%), Positives = 121/354 (34%), Gaps = 48/354 (13%)
Query: 230 REEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERG 289
R+ + D D R + +D R R S D R ER R E + R+R+ ER
Sbjct: 361 RDRERDRDRDRE-RSSDRNKDRSRSREKSRDRERERERERERERERERERE-RERERERE 418
Query: 290 YRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSL---------KKVQKEPIP 340
R R DR+ E E + E + A+ KK ++
Sbjct: 419 REREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKE 478
Query: 341 EEQEMDFRP--VDEGEECSDSEGSHNEEAKEP-------------DKTNKKEGEKTDRVG 385
E+E + R E + + ++++ +P D+ + E ++ DR
Sbjct: 479 AEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKR 538
Query: 386 VASE--ETPQTSSSSARPGTPSDHQSQEAS-------QFERKDEPKTEQTEKAEEETRME 436
E E Q + P ++ Q E Q +++ E + E+ EK E+E + E
Sbjct: 539 EKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKRE 598
Query: 437 NSLPAKVPSRGDEMVADVQQPLSQIPSDTA-------------SPLLILPPPVPNPSPTL 483
+ + + +P+S PS ++ SP I+ P +P
Sbjct: 599 EPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQ 658
Query: 484 RPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKL 537
P +G S P +K + + + +D DD KL
Sbjct: 659 PEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKL 712
Score = 39.7 bits (91), Expect = 0.019
Identities = 49/215 (22%), Positives = 80/215 (37%), Gaps = 15/215 (6%)
Query: 231 EEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGY 290
EE+ G+ E + RR+ ER R + R RE R R ++R+ ER
Sbjct: 292 EEEKGKKEKERQEIEKERRERERER----ERERERREREREREREREREKEKERERERER 347
Query: 291 RRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 350
R R + D DRD + D + E + + S +K + E+E +
Sbjct: 348 DRDRDRTKERDRDRDRERD---RDRDRERSSDRNKDRSRSREKSRDRERERERERERERE 404
Query: 351 DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQ 410
E E + E E + + +KK + D E+ + + +
Sbjct: 405 REREREREREREREREREREREKDKKRDREED-----EEDAYERRKLERKLREKEAAYQE 459
Query: 411 EASQFERKDEPKTEQTEK---AEEETRMENSLPAK 442
+E ++ KT + EK EEE R E + AK
Sbjct: 460 RLKNWEIRERKKTREYEKEAEREEERRREMAKEAK 494
Score = 38.9 bits (89), Expect = 0.033
Identities = 70/332 (21%), Positives = 118/332 (35%), Gaps = 62/332 (18%)
Query: 118 RGRSSSRGRGRGRGECGFYQRSFD-EVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKD 176
R RSS R + R R ++S D E E R RE R + E +R E+ ++
Sbjct: 371 RERSSDRNKDRSRSR----EKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 177 VGKKNGYYCMYSPVLLLGQPLCQGRPNFEEGG------PTSVGRKHEFIRSESENWRIFR 230
KK + R EE + K + +NW I
Sbjct: 427 KDKK------------------RDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRE 468
Query: 231 EEQNGEDEDGGWRLAGSRRDGERWRPH----------SPDGPR----SAGWREHMERRRR 276
++ E E R RR+ + D P+ SA + +R +
Sbjct: 469 RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528
Query: 277 FEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQK 336
E D RDR E+ +++ R L D + E+ + ++++
Sbjct: 529 MEADERDRKREKE---------ELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQ 579
Query: 337 EPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSS 396
EP EE+E EE + E E +E ++ +K K ++S + ++S
Sbjct: 580 EPESEEEE---------EEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSAS 630
Query: 397 SSARPGTPSDHQSQEASQFERKDEPKTEQTEK 428
+A P TP D +S ++ P +Q E+
Sbjct: 631 GNATPNTPGD-ESPCGIIIPHENSPDQQQPEE 661
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,356,058
Number of Sequences: 37866
Number of extensions: 3293477
Number of successful extensions: 141160
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1616
Number of HSP's successfully gapped in prelim test: 1488
Number of HSP's that attempted gapping in prelim test: 23326
Number of HSP's gapped (non-prelim): 37534
length of query: 1320
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1206
effective length of database: 13,930,794
effective search space: 16800537564
effective search space used: 16800537564
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.