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Search of human proteins with 110349797
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110349797 homer 2 isoform 4 [Homo sapiens]
(299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110349797 homer 2 isoform 4 [Homo sapiens] 586 e-168
gi|110349794 homer 2 isoform 3 [Homo sapiens] 556 e-159
gi|46249351 homer 2 isoform 2 [Homo sapiens] 551 e-157
gi|46249349 homer 2 isoform 1 [Homo sapiens] 521 e-148
gi|4759198 homer 1 [Homo sapiens] 296 1e-80
gi|224809410 Homer, neuronal immediate early gene, 3 isoform 2 [... 241 4e-64
gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1 [... 240 1e-63
gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1 [... 240 1e-63
gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3 [... 201 8e-52
gi|56549694 enabled homolog isoform a [Homo sapiens] 69 5e-12
gi|39930375 enabled homolog isoform b [Homo sapiens] 69 5e-12
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 57 3e-08
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 57 3e-08
gi|32698688 citron [Homo sapiens] 53 4e-07
gi|7706687 Enah/Vasp-like [Homo sapiens] 53 4e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 53 4e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 53 4e-07
gi|16262452 cingulin [Homo sapiens] 52 5e-07
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 52 6e-07
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 51 1e-06
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 51 1e-06
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 51 1e-06
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 51 1e-06
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 51 1e-06
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 50 2e-06
gi|157502225 Janus kinase and microtubule interacting protein 3 ... 50 2e-06
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 50 3e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 50 3e-06
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 49 4e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 49 4e-06
>gi|110349797 homer 2 isoform 4 [Homo sapiens]
Length = 299
Score = 586 bits (1511), Expect = e-168
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV 180
IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV
Sbjct: 121 IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV 180
Query: 181 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAE 240
KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAE
Sbjct: 181 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAE 240
Query: 241 RDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 299
RDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
Sbjct: 241 RDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 299
>gi|110349794 homer 2 isoform 3 [Homo sapiens]
Length = 288
Score = 556 bits (1434), Expect = e-159
Identities = 288/299 (96%), Positives = 288/299 (96%), Gaps = 11/299 (3%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV 180
IETSSNHSQ ASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV
Sbjct: 121 IETSSNHSQ-----------ASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV 169
Query: 181 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAE 240
KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAE
Sbjct: 170 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAE 229
Query: 241 RDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 299
RDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
Sbjct: 230 RDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 288
>gi|46249351 homer 2 isoform 2 [Homo sapiens]
Length = 354
Score = 551 bits (1420), Expect = e-157
Identities = 296/354 (83%), Positives = 299/354 (84%), Gaps = 55/354 (15%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQS---- 176
IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQS
Sbjct: 121 IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV 180
Query: 177 ------------------------AANVK---------------------------NEIN 185
AA+V+ +EIN
Sbjct: 181 KKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEIN 240
Query: 186 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN 245
REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN
Sbjct: 241 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN 300
Query: 246 LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 299
LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
Sbjct: 301 LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 354
>gi|46249349 homer 2 isoform 1 [Homo sapiens]
Length = 343
Score = 521 bits (1343), Expect = e-148
Identities = 285/354 (80%), Positives = 288/354 (81%), Gaps = 66/354 (18%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 IETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQS---- 176
IETSSNHSQ ASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQS
Sbjct: 121 IETSSNHSQ-----------ASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANV 169
Query: 177 ------------------------AANVK---------------------------NEIN 185
AA+V+ +EIN
Sbjct: 170 KKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEIN 229
Query: 186 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN 245
REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN
Sbjct: 230 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN 289
Query: 246 LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 299
LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
Sbjct: 290 LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 343
>gi|4759198 homer 1 [Homo sapiens]
Length = 354
Score = 296 bits (758), Expect = 1e-80
Identities = 169/350 (48%), Positives = 220/350 (62%), Gaps = 55/350 (15%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
MGEQPIF+TRAHVFQIDPNTKKNW+P SK AVTVSYFYD TRN YRIIS+DG+K IINST
Sbjct: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
ITPNMTFTKTSQKFGQWADSRANTV+GLGFSSE L+KFAEKFQE KEAA++AK+K+QEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK 120
Query: 121 IETSSNHSQES-GRETPSSTQASSVNGTDDEKA--------------------SHAGPAN 159
+E +S SQES G + S S+NGTDDE+ SH+ +
Sbjct: 121 MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAIS 180
Query: 160 TH-------LKSENDKLKIALTQSAANVK---------------------------NEIN 185
H LK N KL AL +S ANVK ++ N
Sbjct: 181 KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN 240
Query: 186 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN 245
T+L + I+ELE L+ KE E++ L+++ + +L + + +++KL+ E N++
Sbjct: 241 AVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD 300
Query: 246 LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 295
LE ++ L+ +E+S+ Q + LK+ LE+LDGKI +L + R L+KL
Sbjct: 301 LEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKL 350
>gi|224809410 Homer, neuronal immediate early gene, 3 isoform 2
[Homo sapiens]
Length = 358
Score = 241 bits (616), Expect = 4e-64
Identities = 145/349 (41%), Positives = 206/349 (59%), Gaps = 57/349 (16%)
Query: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT+FAEKFQEVKEAA++A++K+Q+ E
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGE 125
Query: 123 TSSNHSQESGRETPSSTQASSVNGTDDEK------ASHAGPANTH--------------- 161
+S + + P S S+ NG +EK A GP
Sbjct: 126 LTSPALGLASHQVPPSPLVSA-NGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQ 184
Query: 162 -------LKSENDKLKIALTQS---AANVKNEINREKEKNTQLKRRIEELEAELREKETE 211
L+ N+KL AL ++ AA + ++ ++ + +L++R+ ELEA+ + T
Sbjct: 185 WEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTP 244
Query: 212 LKD----------------LRKQSEIIPQLMSECEYVSEKLEAAERD---------NQNL 246
+ ++ + + I L S+ E LEAAER+ N L
Sbjct: 245 TGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQTRNAEL 304
Query: 247 EDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 295
E ++R+++ +EE++ + + E+ ++LD + +L + R GL++L
Sbjct: 305 EHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARL 353
>gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 240 bits (613), Expect = 1e-63
Identities = 145/352 (41%), Positives = 206/352 (58%), Gaps = 60/352 (17%)
Query: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT+FAEKFQEVKEAA++A++K+Q+ E
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGE 125
Query: 123 TSSNHSQESGRETPSSTQASSVNGTDDEK------ASHAGPANTH--------------- 161
+S + + P S S+ NG +EK A GP
Sbjct: 126 LTSPALGLASHQVPPSPLVSA-NGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQ 184
Query: 162 -------LKSENDKLKIALTQ---SAANVKNEINREKEKNTQLKRRIEELEAELREKETE 211
L+ N+KL AL + +AA + ++ ++ + +L++R+ ELEA+ + T
Sbjct: 185 WEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTP 244
Query: 212 LKD----------------LRKQSEIIPQLMSECEYVSEKLEAAERD------------N 243
+ ++ + + I L S+ E LEAAER+ N
Sbjct: 245 TGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRN 304
Query: 244 QNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 295
LE ++R+++ +EE++ + + E+ ++LD + +L + R GL++L
Sbjct: 305 AELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARL 356
>gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 240 bits (613), Expect = 1e-63
Identities = 145/352 (41%), Positives = 206/352 (58%), Gaps = 60/352 (17%)
Query: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT+FAEKFQEVKEAA++A++K+Q+ E
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGE 125
Query: 123 TSSNHSQESGRETPSSTQASSVNGTDDEK------ASHAGPANTH--------------- 161
+S + + P S S+ NG +EK A GP
Sbjct: 126 LTSPALGLASHQVPPSPLVSA-NGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQ 184
Query: 162 -------LKSENDKLKIALTQ---SAANVKNEINREKEKNTQLKRRIEELEAELREKETE 211
L+ N+KL AL + +AA + ++ ++ + +L++R+ ELEA+ + T
Sbjct: 185 WEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTP 244
Query: 212 LKD----------------LRKQSEIIPQLMSECEYVSEKLEAAERD------------N 243
+ ++ + + I L S+ E LEAAER+ N
Sbjct: 245 TGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRN 304
Query: 244 QNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 295
LE ++R+++ +EE++ + + E+ ++LD + +L + R GL++L
Sbjct: 305 AELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARL 356
>gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3
[Homo sapiens]
Length = 325
Score = 201 bits (510), Expect = 8e-52
Identities = 126/324 (38%), Positives = 181/324 (55%), Gaps = 40/324 (12%)
Query: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT Q A +EK+
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLT------QVPPSPLVSANGPGEEKLF 119
Query: 123 TSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQ---SAAN 179
S + E + S + + A L+ N+KL AL + +AA
Sbjct: 120 RSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFA---LQDSNNKLAGALREANAAAAQ 176
Query: 180 VKNEINREKEKNTQLKRRIEELEAELREKETELKD----------------LRKQSEIIP 223
+ ++ ++ + +L++R+ ELEA+ + T + ++ + + I
Sbjct: 177 WRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQ 236
Query: 224 QLMSECEYVSEKLEAAERD------------NQNLEDKVRSLKTDIEESKYRQRHLKVEL 271
L S+ E LEAAER+ N LE ++R+++ +EE++ + + E+
Sbjct: 237 TLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEV 296
Query: 272 KSFLEVLDGKIDDLHDFRRGLSKL 295
++LD + +L + R GL++L
Sbjct: 297 GRAAQLLDVSLFELSELREGLARL 320
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 68.9 bits (167), Expect = 5e-12
Identities = 67/281 (23%), Positives = 117/281 (41%), Gaps = 38/281 (13%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPA--SKQAVTVSYFYDVTRNSYRIIS--VDGAKVI 56
M EQ I RA V D KK W+PA S V ++ N++R++ + +V+
Sbjct: 1 MSEQSICQARAAVMVYDDANKK-WVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVV 59
Query: 57 INSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDK 116
IN I + + + +Q F QW D+R V+GL F S++ FA E
Sbjct: 60 INCAIPKGLKYNQATQTFHQWRDAR--QVYGLNFGSKEDANVFASAMMHALEVL------ 111
Query: 117 TQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQS 176
+SQE+G P + GP+ L+ + +L+ Q
Sbjct: 112 ----------NSQETGPTLPRQNSQLPAQVQN-------GPSQEELEIQRRQLQEQQRQK 154
Query: 177 AANVKNEINREKEKNTQLKR------RIEELEAELREKETELKDLRKQSEIIPQLMSECE 230
+ + RE+ + +L+R R+E E + E E ++ +Q + Q E +
Sbjct: 155 ELE-RERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQ 213
Query: 231 YVSEKLEAAERDNQNLEDKVRSLKTDIE-ESKYRQRHLKVE 270
E+ E +R+ Q +++ R + + E + + RQ L+ E
Sbjct: 214 ERLERQERLDRERQERQERERLERLERERQERERQEQLERE 254
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 68.9 bits (167), Expect = 5e-12
Identities = 67/281 (23%), Positives = 117/281 (41%), Gaps = 38/281 (13%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPA--SKQAVTVSYFYDVTRNSYRIIS--VDGAKVI 56
M EQ I RA V D KK W+PA S V ++ N++R++ + +V+
Sbjct: 1 MSEQSICQARAAVMVYDDANKK-WVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVV 59
Query: 57 INSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDK 116
IN I + + + +Q F QW D+R V+GL F S++ FA E
Sbjct: 60 INCAIPKGLKYNQATQTFHQWRDAR--QVYGLNFGSKEDANVFASAMMHALEVL------ 111
Query: 117 TQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQS 176
+SQE+G P + GP+ L+ + +L+ Q
Sbjct: 112 ----------NSQETGPTLPRQNSQLPAQVQN-------GPSQEELEIQRRQLQEQQRQK 154
Query: 177 AANVKNEINREKEKNTQLKR------RIEELEAELREKETELKDLRKQSEIIPQLMSECE 230
+ + RE+ + +L+R R+E E + E E ++ +Q + Q E +
Sbjct: 155 ELE-RERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQ 213
Query: 231 YVSEKLEAAERDNQNLEDKVRSLKTDIE-ESKYRQRHLKVE 270
E+ E +R+ Q +++ R + + E + + RQ L+ E
Sbjct: 214 ERLERQERLDRERQERQERERLERLERERQERERQEQLERE 254
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 56.6 bits (135), Expect = 3e-08
Identities = 49/213 (23%), Positives = 105/213 (49%), Gaps = 14/213 (6%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKT--QEKIETSSNHSQESGRETPSSTQASSVNGTDDE 150
EQ+ ++ + +++K+ K+ T E +E ++ E E + ++
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASM--- 718
Query: 151 KASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKE------KNTQLKRRIEELEAE 204
K + N L+SE ++LK L A+ K E +N +L++ +E +
Sbjct: 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKK 778
Query: 205 LREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQ 264
+++ E+EL+DL +++ + + + E + S++LE E++N++LE + L+ D ++ +
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Query: 265 RHLK--VELK-SFLEVLDGKIDDLHDFRRGLSK 294
+ L+ E+K + LE + KI +L + LSK
Sbjct: 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/194 (18%), Positives = 80/194 (41%), Gaps = 37/194 (19%)
Query: 105 EVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKS 164
++K + +D EK++T Q+ + T G + E+ H +
Sbjct: 900 DIKTLVTLREDLVSEKLKT-----QQMNNDLEKLTHELEKIGLNKERLLH-----DEQST 949
Query: 165 ENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQ 224
++ + K+ ++ + +K + ++EK L+ R+EE ++ ELK ++K E + Q
Sbjct: 950 DDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1009
Query: 225 LMSECEY---------------------------VSEKLEAAERDNQNLEDKVRSLKTDI 257
E V ++L ER+N L+ + ++LKT +
Sbjct: 1010 RQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQL 1069
Query: 258 EESKYRQRHLKVEL 271
++ + + +L+ ++
Sbjct: 1070 KQLETQNNNLQAQI 1083
Score = 39.3 bits (90), Expect = 0.004
Identities = 31/140 (22%), Positives = 69/140 (49%), Gaps = 24/140 (17%)
Query: 156 GPANTHLKSENDKLKIALTQSAANVKNEINREKE--------------KNTQLKRRIEEL 201
G A+ LK E + + L++ ++NEI +EK+ + QL++ IE L
Sbjct: 488 GNASKILKMEKENQR--LSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL 545
Query: 202 EAELREKETELKDLRKQSEIIPQLMSECEYVSE-----KLEAAERDNQNLEDKVRSLKTD 256
E ++K L +++E + Q +S S+ +++ E++N+ L + ++ +
Sbjct: 546 R---ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSK 602
Query: 257 IEESKYRQRHLKVELKSFLE 276
+ + ++ +R +K EL+ + E
Sbjct: 603 LSKIEFEKRQIKKELEHYKE 622
Score = 38.1 bits (87), Expect = 0.009
Identities = 43/195 (22%), Positives = 79/195 (40%), Gaps = 16/195 (8%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKA 152
EQ+ + +++ ++I+ + + IE + ES +ET S +K
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKE 616
Query: 153 SHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLK---RRIEELEAELREKE 209
H K + ++ + L +++ E ++K T LK +IE LE E E E
Sbjct: 617 LE------HYKEKGERAE-ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELE 669
Query: 210 TELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLK------TDIEESKYR 263
E + L+K + L + E + ++ + +N L V SLK ++
Sbjct: 670 RENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKE 729
Query: 264 QRHLKVELKSFLEVL 278
K +LK LE+L
Sbjct: 730 LESEKEQLKKGLELL 744
Score = 37.4 bits (85), Expect = 0.016
Identities = 39/199 (19%), Positives = 86/199 (43%), Gaps = 8/199 (4%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRE--TPSSTQASSVNGTDDE 150
E +L +K E+KE KIA + ++E S+N++Q+ +E T + D+E
Sbjct: 958 ESKLESTLKKSLEIKEE-KIAA--LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEE 1014
Query: 151 KASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKET 210
+ + P + ++ ++ T+ VK+ + + N L+ + L+ +L++ ET
Sbjct: 1015 RMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLET 1074
Query: 211 ELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVE 270
+ +L+ Q I L + + E+ + N L+ + +L + + L ++
Sbjct: 1075 QNNNLQAQ---ILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1131
Query: 271 LKSFLEVLDGKIDDLHDFR 289
S + I + D +
Sbjct: 1132 QSSLENENESVIKEREDLK 1150
Score = 31.6 bits (70), Expect = 0.89
Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 9/118 (7%)
Query: 175 QSAANVKNEINREKEKNTQL-------KRRIEELEAELREKETELKDLRKQSEIIPQLMS 227
Q ++ E+ R +++N L + +EL+A LREK + L + + +
Sbjct: 279 QELEQMEIELKRLQQENMNLLSDARSARMYRDELDA-LREKAVRVDKLESEVSRYKERLH 337
Query: 228 ECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDL 285
+ E+ ++E + DNQ L + L+ +E ++ R L K L+ L K+ D+
Sbjct: 338 DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-LKAKLHDM 394
Score = 30.4 bits (67), Expect = 2.0
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 174 TQSAANVKNEINREKEKNTQLKRRIEE-------LEAELREKETELKDLRKQSEIIPQLM 226
T+S ++ E+ K K +L++ +EE + EL + E ELK L++++ +
Sbjct: 243 TESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDA 302
Query: 227 SECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVE 270
++L+A E VR K + E S+Y++R +E
Sbjct: 303 RSARMYRDELDALR------EKAVRVDKLESEVSRYKERLHDIE 340
Score = 28.1 bits (61), Expect = 9.8
Identities = 37/137 (27%), Positives = 66/137 (48%), Gaps = 18/137 (13%)
Query: 162 LKSENDKLKIALTQSAANVKNEINREK-----EKNTQLKRRIEELEAELREKETELKDLR 216
L+ EN +LK L ++ +++R+K E+N L+ ++ E EL+ +
Sbjct: 380 LEKENLQLKAKLHDM--EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 217 KQSEI--IPQ--LMSEC-EYVSEKLEAAERDNQNLEDKVRSLKTDIEESK-YRQRHLKVE 270
+ SE+ PQ L E E S +L E +NQ+L V L+T ++ + + LK+E
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 271 -----LKSFLEVLDGKI 282
L +E+L+ +I
Sbjct: 498 KENQRLSKKVEILENEI 514
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 56.6 bits (135), Expect = 3e-08
Identities = 49/213 (23%), Positives = 105/213 (49%), Gaps = 14/213 (6%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKT--QEKIETSSNHSQESGRETPSSTQASSVNGTDDE 150
EQ+ ++ + +++K+ K+ T E +E ++ E E + ++
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASM--- 718
Query: 151 KASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKE------KNTQLKRRIEELEAE 204
K + N L+SE ++LK L A+ K E +N +L++ +E +
Sbjct: 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKK 778
Query: 205 LREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQ 264
+++ E+EL+DL +++ + + + E + S++LE E++N++LE + L+ D ++ +
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Query: 265 RHLK--VELK-SFLEVLDGKIDDLHDFRRGLSK 294
+ L+ E+K + LE + KI +L + LSK
Sbjct: 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Score = 41.6 bits (96), Expect = 9e-04
Identities = 37/194 (19%), Positives = 81/194 (41%), Gaps = 38/194 (19%)
Query: 105 EVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKS 164
++K + +D EK++T Q+ + T G + E+ H +S
Sbjct: 900 DIKTLVTLREDLVSEKLKT-----QQMNNDLEKLTHELEKIGLNKERLLHDE------QS 948
Query: 165 ENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQ 224
+D+ K+ ++ + +K + ++EK L+ R+EE ++ ELK ++K E + Q
Sbjct: 949 TDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1008
Query: 225 LMSECEY---------------------------VSEKLEAAERDNQNLEDKVRSLKTDI 257
E V ++L ER+N L+ + ++LKT +
Sbjct: 1009 RQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQL 1068
Query: 258 EESKYRQRHLKVEL 271
++ + + +L+ ++
Sbjct: 1069 KQLETQNNNLQAQI 1082
Score = 39.3 bits (90), Expect = 0.004
Identities = 31/140 (22%), Positives = 69/140 (49%), Gaps = 24/140 (17%)
Query: 156 GPANTHLKSENDKLKIALTQSAANVKNEINREKE--------------KNTQLKRRIEEL 201
G A+ LK E + + L++ ++NEI +EK+ + QL++ IE L
Sbjct: 488 GNASKILKMEKENQR--LSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL 545
Query: 202 EAELREKETELKDLRKQSEIIPQLMSECEYVSE-----KLEAAERDNQNLEDKVRSLKTD 256
E ++K L +++E + Q +S S+ +++ E++N+ L + ++ +
Sbjct: 546 R---ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSK 602
Query: 257 IEESKYRQRHLKVELKSFLE 276
+ + ++ +R +K EL+ + E
Sbjct: 603 LSKIEFEKRQIKKELEHYKE 622
Score = 38.1 bits (87), Expect = 0.009
Identities = 43/195 (22%), Positives = 79/195 (40%), Gaps = 16/195 (8%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKA 152
EQ+ + +++ ++I+ + + IE + ES +ET S +K
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKE 616
Query: 153 SHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLK---RRIEELEAELREKE 209
H K + ++ + L +++ E ++K T LK +IE LE E E E
Sbjct: 617 LE------HYKEKGERAE-ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELE 669
Query: 210 TELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLK------TDIEESKYR 263
E + L+K + L + E + ++ + +N L V SLK ++
Sbjct: 670 RENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKE 729
Query: 264 QRHLKVELKSFLEVL 278
K +LK LE+L
Sbjct: 730 LESEKEQLKKGLELL 744
Score = 37.4 bits (85), Expect = 0.016
Identities = 39/199 (19%), Positives = 86/199 (43%), Gaps = 8/199 (4%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRE--TPSSTQASSVNGTDDE 150
E +L +K E+KE KIA + ++E S+N++Q+ +E T + D+E
Sbjct: 957 ESKLESTLKKSLEIKEE-KIAA--LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEE 1013
Query: 151 KASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKET 210
+ + P + ++ ++ T+ VK+ + + N L+ + L+ +L++ ET
Sbjct: 1014 RMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLET 1073
Query: 211 ELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVE 270
+ +L+ Q I L + + E+ + N L+ + +L + + L ++
Sbjct: 1074 QNNNLQAQ---ILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1130
Query: 271 LKSFLEVLDGKIDDLHDFR 289
S + I + D +
Sbjct: 1131 QSSLENENESVIKEREDLK 1149
Score = 31.6 bits (70), Expect = 0.89
Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 9/118 (7%)
Query: 175 QSAANVKNEINREKEKNTQL-------KRRIEELEAELREKETELKDLRKQSEIIPQLMS 227
Q ++ E+ R +++N L + +EL+A LREK + L + + +
Sbjct: 279 QELEQMEIELKRLQQENMNLLSDARSARMYRDELDA-LREKAVRVDKLESEVSRYKERLH 337
Query: 228 ECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDL 285
+ E+ ++E + DNQ L + L+ +E ++ R L K L+ L K+ D+
Sbjct: 338 DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-LKAKLHDM 394
Score = 30.4 bits (67), Expect = 2.0
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 174 TQSAANVKNEINREKEKNTQLKRRIEE-------LEAELREKETELKDLRKQSEIIPQLM 226
T+S ++ E+ K K +L++ +EE + EL + E ELK L++++ +
Sbjct: 243 TESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDA 302
Query: 227 SECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVE 270
++L+A E VR K + E S+Y++R +E
Sbjct: 303 RSARMYRDELDALR------EKAVRVDKLESEVSRYKERLHDIE 340
Score = 28.1 bits (61), Expect = 9.8
Identities = 37/137 (27%), Positives = 66/137 (48%), Gaps = 18/137 (13%)
Query: 162 LKSENDKLKIALTQSAANVKNEINREK-----EKNTQLKRRIEELEAELREKETELKDLR 216
L+ EN +LK L ++ +++R+K E+N L+ ++ E EL+ +
Sbjct: 380 LEKENLQLKAKLHDM--EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 217 KQSEI--IPQ--LMSEC-EYVSEKLEAAERDNQNLEDKVRSLKTDIEESK-YRQRHLKVE 270
+ SE+ PQ L E E S +L E +NQ+L V L+T ++ + + LK+E
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 271 -----LKSFLEVLDGKI 282
L +E+L+ +I
Sbjct: 498 KENQRLSKKVEILENEI 514
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 12/147 (8%)
Query: 131 SGRETP----SSTQASSVNGTDDEKASHA-GPANTHLKSENDKLKIALTQSAANVKNEIN 185
SG E P S ++A + G + S PA T S +K + ++ + +++ +
Sbjct: 410 SGEELPFVGFSYSKALGILGRSESVVSGLDSPAKT---SSMEKKLLIKSKELQDSQDKCH 466
Query: 186 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQ----LMSECEYVSEKLEAAER 241
+ +++ T+L RR+ E+EA L +KE ELK Q ++ Q ++EC + LE A
Sbjct: 467 KMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARM 526
Query: 242 DNQNLEDKVRSLKTDIEESKYRQRHLK 268
+ +DK L DI E + + +K
Sbjct: 527 EVSQEDDKALQLLHDIREQSRKLQEIK 553
Score = 37.7 bits (86), Expect = 0.012
Identities = 35/145 (24%), Positives = 67/145 (46%), Gaps = 17/145 (11%)
Query: 162 LKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEI 221
L+++N KL+ L + + ++ + +K + +L+ R+ E+ E E++ ELK R+ +E+
Sbjct: 826 LEAQNRKLEEQLEK----ISHQDHSDKNRLLELETRLREVSLEHEEQKLELK--RQLTEL 879
Query: 222 IPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGK 281
L +L A + LE ++R KT++EE+ L + + + K
Sbjct: 880 QLSLQER----ESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRK 935
Query: 282 IDDLH-------DFRRGLSKLGTDN 299
D L D L++L DN
Sbjct: 936 FDALRNSCTVITDLEEQLNQLTEDN 960
Score = 37.0 bits (84), Expect = 0.021
Identities = 32/150 (21%), Positives = 66/150 (44%), Gaps = 11/150 (7%)
Query: 102 KFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTH 161
+ ++ K + + +E+I+ + H E R+ + + +V +E+ + N
Sbjct: 903 QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAE 962
Query: 162 LKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEI 221
L ++N L L + A+ +EI QL+ ++ L E+ E+E + L Q +
Sbjct: 963 LNNQNFYLSKQLDE-ASGANDEI-------VQLRSEVDHLRREITEREMQ---LTSQKQT 1011
Query: 222 IPQLMSECEYVSEKLEAAERDNQNLEDKVR 251
+ L + C + E++ E N L +K R
Sbjct: 1012 MEALKTTCTMLEEQVMDLEALNDELLEKER 1041
Score = 34.7 bits (78), Expect = 0.10
Identities = 31/175 (17%), Positives = 74/175 (42%), Gaps = 7/175 (4%)
Query: 104 QEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLK 163
+ +K ++ + Q+K + + + Q ++ D + T L+
Sbjct: 800 RNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLR 859
Query: 164 S---ENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQS- 219
E+++ K+ L + ++ + + + T L+ LE++LR+ +TEL++ ++
Sbjct: 860 EVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAE 919
Query: 220 EIIPQLMSECEYVSEKLEAAERD---NQNLEDKVRSLKTDIEESKYRQRHLKVEL 271
E I L + + + K +A +LE+++ L D E + +L +L
Sbjct: 920 EEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQL 974
Score = 34.3 bits (77), Expect = 0.14
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 184 INREKEKNTQLKRRIEELE--AELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAER 241
++ EK+ + +RI E EL KE + + L Q + Q + + E +S+KL E+
Sbjct: 1068 LDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKL-KAESLSDKLNDLEK 1126
Query: 242 DNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSK 294
+ LE RSL+ +E + ++ L E + +D + + + +GL +
Sbjct: 1127 KHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQE 1179
Score = 30.8 bits (68), Expect = 1.5
Identities = 45/200 (22%), Positives = 83/200 (41%), Gaps = 19/200 (9%)
Query: 100 AEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPAN 159
+ K QE+KE + Q ++E + + S+ + S + ++ ++ A
Sbjct: 546 SRKLQEIKE------QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEF 599
Query: 160 THLKSE-NDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQ 218
+E KL A Q V EK N + + +I+EL+ +L + + +
Sbjct: 600 KRKATECQHKLLKAKDQGKPEVGEYAKLEKI-NAEQQLKIQELQEKLEKAVKASTEATEL 658
Query: 219 SEIIPQLMSECEYVSEKLEAAERDNQNLEDKV---RSLKTDIEESKYRQRHLKVELK--- 272
+ I Q E EKL+ E ++ + K+ L+ E++ +HL+V LK
Sbjct: 659 LQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKE 718
Query: 273 ----SFLEVLDGKI-DDLHD 287
++VLD +I DL D
Sbjct: 719 QHYEEKIKVLDNQIKKDLAD 738
>gi|7706687 Enah/Vasp-like [Homo sapiens]
Length = 418
Score = 52.8 bits (125), Expect = 4e-07
Identities = 31/103 (30%), Positives = 58/103 (56%), Gaps = 8/103 (7%)
Query: 3 EQPIFTTRAHVFQIDPNTKKNWMPAS--KQAVT-VSYFYDVTRNSYRIISV--DGAKVII 57
EQ I RA V D +T K W+P +Q + ++ +++ N++R++ V +V+I
Sbjct: 5 EQSICQARASVMVYD-DTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVI 63
Query: 58 NSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFA 100
N +I + + + + F QW D+R V+GL F+S+++ T F+
Sbjct: 64 NYSIVKGLKYNQATPTFHQWRDAR--QVYGLNFASKEEATTFS 104
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 52.8 bits (125), Expect = 4e-07
Identities = 42/179 (23%), Positives = 85/179 (47%), Gaps = 4/179 (2%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKA 152
EQ+ + EK ++ KE ++A++K ++K E+ R+ + ++E+
Sbjct: 600 EQKFAQIDEKTEKAKEE-RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658
Query: 153 SHAGPANTHLKSENDKL-KIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETE 211
H + E ++L K A + A + + RE+E+ Q +R E E E RE+E +
Sbjct: 659 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ 718
Query: 212 LKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVE 270
L + ++ E +L +E E + E+ +A + L+ ++ K E+ + +R L+ E
Sbjct: 719 LAEQERRRE-QERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEE 775
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 52.8 bits (125), Expect = 4e-07
Identities = 42/179 (23%), Positives = 85/179 (47%), Gaps = 4/179 (2%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKA 152
EQ+ + EK ++ KE ++A++K ++K E+ R+ + ++E+
Sbjct: 596 EQKFAQIDEKTEKAKEE-RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Query: 153 SHAGPANTHLKSENDKL-KIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETE 211
H + E ++L K A + A + + RE+E+ Q +R E E E RE+E +
Sbjct: 655 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ 714
Query: 212 LKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVE 270
L + ++ E +L +E E + E+ +A + L+ ++ K E+ + +R L+ E
Sbjct: 715 LAEQERRRE-QERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEE 771
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 52.4 bits (124), Expect = 5e-07
Identities = 50/230 (21%), Positives = 104/230 (45%), Gaps = 26/230 (11%)
Query: 77 WADSRANTVFGLGFSSE--QQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRE 134
WA T GL + Q+L + + Q ++ A++ K+ ++++ ++ R
Sbjct: 897 WASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRS 956
Query: 135 TPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQL 194
+A + G + EK S T L E + +++ LT ++++++ + + Q
Sbjct: 957 --QDDRARQLKGLE-EKVSRL---ETELDEEKNTVEL-LTDRVNRGRDQVDQLRTELMQE 1009
Query: 195 KRRIEELEAELREKETELKDLR----------KQSEIIPQLMSECEYVSEKLEAAERD-- 242
+ ++LE + E + KDL+ K S + QL S+ + + E+L+A ER+
Sbjct: 1010 RSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKT 1069
Query: 243 -----NQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHD 287
N+ LE KV+ L IE+ + K +L ++ L ++D+ +
Sbjct: 1070 VLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEE 1119
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/155 (27%), Positives = 69/155 (44%), Gaps = 31/155 (20%)
Query: 173 LTQSAANVKNEINREKEKNTQLKRRIEELEAELREK----------ETELKDLRKQSEII 222
L Q A V+ + +E+N + +RRI LE +L+E E L+D ++ E
Sbjct: 714 LGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAE 773
Query: 223 PQLMSECEYVSE---------------KLEAAERDNQNLEDKVRSLKTDI-EESKYRQ-- 264
Q + E S+ +LE A+R L + ++L + EE K R+
Sbjct: 774 KQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVL 833
Query: 265 RHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN 299
R K EL+ +LD +D L+ + L K+G D+
Sbjct: 834 RRGKAELEEQKRLLDRTVDRLN---KELEKIGEDS 865
Score = 34.3 bits (77), Expect = 0.14
Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 39/214 (18%)
Query: 79 DSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSS 138
D RA + GL E+++++ + E K ++ D+ Q T
Sbjct: 958 DDRARQLKGL----EEKVSRLETELDEEKNTVELLTDRVNR------GRDQVDQLRTELM 1007
Query: 139 TQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREK-EKNTQLKRR 197
+ S+ + +K S L+ +N LK L S K + + E QL +
Sbjct: 1008 QERSARQDLECDKIS--------LERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQ- 1058
Query: 198 IEELEAELREK----ETELKDLRKQSEIIPQLMSECEYVSEK--------------LEAA 239
E L+AE REK T K RK E+ Q+ E ++V+++ ++ A
Sbjct: 1059 -ERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEA 1117
Query: 240 ERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKS 273
E + + L+ + + ++EE L+ +KS
Sbjct: 1118 EEEIERLDGLRKKAQREVEEQHEVNEQLQARIKS 1151
Score = 33.5 bits (75), Expect = 0.23
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 10/113 (8%)
Query: 179 NVKNEINREKEKNTQLKRRIEELEAELRE-------KETELKDLRKQSEIIPQLMSECEY 231
N+K +++ ++ L+ ++ EL+ +L+ KE LKDL + E++ +++ +
Sbjct: 426 NMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQR 485
Query: 232 VSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDD 284
V E+L ER+ L+ +LK ++ H++ + + E L + D
Sbjct: 486 VEEQLRLRERELTALKG---ALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQD 535
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/103 (22%), Positives = 52/103 (50%), Gaps = 7/103 (6%)
Query: 181 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAE 240
K ++ K++ QL+ EE+E EL EK ++ L+++ E + + ++E +
Sbjct: 579 KEDLRATKQELLQLRMEKEEMEEELGEK---IEVLQRELEQARASAGD----TRQVEVLK 631
Query: 241 RDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKID 283
++ +++++ L+ + + + RH EL+ L VL + D
Sbjct: 632 KELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEAD 674
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 52.0 bits (123), Expect = 6e-07
Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 9/115 (7%)
Query: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASK--QAVT-VSYFYDVTRNSYRIIS---VDGAK 54
M E I ++RA V D K+ W+PA QA + V +++ T NS+R++ +
Sbjct: 1 MSETVICSSRATVMLYDDGNKR-WLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQ 59
Query: 55 VIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEA 109
V+IN I + + + + F QW D+R V+GL F S++ +FA EA
Sbjct: 60 VVINCAIVRGVKYNQATPNFHQWRDAR--QVWGLNFGSKEDAAQFAAGMASALEA 112
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/191 (25%), Positives = 85/191 (44%), Gaps = 24/191 (12%)
Query: 91 SSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDE 150
S Q K E + +K+ + I D + E + + QA S D+E
Sbjct: 622 SQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKS---RDEE 678
Query: 151 KASHAGPANTHLKSEND-----------KLKIALTQSAANVKNEINREKEKNTQLKRRIE 199
A+ T LK E D L+ T+ N++ + K++ ++ + I
Sbjct: 679 TATII----TQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIR 734
Query: 200 ELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEE 259
L+AE E++ K R Q E +L S+C+ ++E+L E +N+ L+ K + LK +EE
Sbjct: 735 TLKAESLEEKNMAKIHRGQLE---KLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEE 791
Query: 260 SKYRQRHLKVE 270
R++H+ +E
Sbjct: 792 ---REKHISIE 799
Score = 39.7 bits (91), Expect = 0.003
Identities = 39/183 (21%), Positives = 76/183 (41%), Gaps = 24/183 (13%)
Query: 94 QQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETP-SSTQASSVNGTDDEKA 152
+ TK AE++ + ++ K++ +++ E +QES R+ + E
Sbjct: 452 EDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETV 511
Query: 153 SHAGPANTHLKSENDKLKIALTQSAANVKN-----------------EINREKEKNTQLK 195
N + E D+LK L + ++N E++ ++EK +K
Sbjct: 512 DELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIK 571
Query: 196 RRIEELEAELREKETEL----KDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVR 251
+LE E++ + +L+KQS+I Q+ E ++ E E AE +DK +
Sbjct: 572 SHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEE--EIAELKKSQAQDKAK 629
Query: 252 SLK 254
L+
Sbjct: 630 LLE 632
Score = 35.8 bits (81), Expect = 0.047
Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 17/169 (10%)
Query: 132 GRETPSSTQASSVNGTDDEKASHAGPA---NTHLKSENDKLKIALTQSAANVKNEINREK 188
G+E ++ + S + + K +GP + H K K L +K NREK
Sbjct: 832 GKEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRWLAESKTK--LQWLCEELKERENREK 889
Query: 189 EKNTQLKRRIEELEAELREKETEL----KDLRKQSEIIPQLMSECEYVSEKLEAAERDNQ 244
QL ++L KE+EL + + +Q +++ ++ E + E+ + + +
Sbjct: 890 NLRHQLMLCRQQLRNLTENKESELQCLFQQIERQEQLLDEIHREKRDLLEETQRKDEEMG 949
Query: 245 NLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLS 293
+L+D+V +L+T + + L+S E L ++D DFR S
Sbjct: 950 SLQDRVIALETSTQVA-------LDHLESVPEKL-SLLEDFKDFRDSCS 990
Score = 33.1 bits (74), Expect = 0.31
Identities = 33/189 (17%), Positives = 84/189 (44%), Gaps = 10/189 (5%)
Query: 91 SSEQQLTKFAEKFQEVK---EAAKIAKDKTQEKIETSSNHSQESGRETP---SSTQASSV 144
+ E+Q + ++ +E++ + + + +I + H++++ ++ S Q S
Sbjct: 411 NGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQQSEA 470
Query: 145 NGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNE-INREKEKNTQLKRRIEELEA 203
+ EK KLK + A ++E ++ KN Q+ + +EL+
Sbjct: 471 LKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKT 530
Query: 204 ELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYR 263
+L ++++LRK+ + ++++ E+L + E ++++ L+ +++ S
Sbjct: 531 QLYAALQQIENLRKE---LNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKNSLDT 587
Query: 264 QRHLKVELK 272
L+ ELK
Sbjct: 588 IHRLESELK 596
Score = 32.7 bits (73), Expect = 0.40
Identities = 25/107 (23%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 182 NEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAER 241
NE +++ + +++RR++ELE E+R E EL + R+Q ++ + E + ++ A+
Sbjct: 208 NEAQKQEVVSDRVERRLQELEREMR-TERELVE-RRQDQLGLMSLQLQEALKKQEAKADE 265
Query: 242 DNQNLEDKVRSLKTD---IEESKYRQRHLKVELKSFLEVLDGKIDDL 285
+++K+R +T+ +E+ R L + + E L ++++L
Sbjct: 266 HEGAIKNKLRQTETEKNQLEQELELSRRLLNQSEGSRETLLHQVEEL 312
Score = 32.3 bits (72), Expect = 0.52
Identities = 26/118 (22%), Positives = 55/118 (46%), Gaps = 7/118 (5%)
Query: 102 KFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKAS--HAGPAN 159
+ +++ + + K K ++ I+ H ++ E + + +++ + H G
Sbjct: 696 ELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNMAKIHRGQLE 755
Query: 160 THLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRK 217
LKS+ D+L LTQ+ +NE + K K LK ++EE E + +E L+ + +
Sbjct: 756 K-LKSQCDRLTEELTQN----ENENKKLKLKYQCLKDQLEEREKHISIEEEHLRRMEE 808
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 50.8 bits (120), Expect = 1e-06
Identities = 61/272 (22%), Positives = 116/272 (42%), Gaps = 39/272 (14%)
Query: 38 YDVTRNSYRIISVDGAKVIINSTITPNMTF-TKTSQKFGQWADSRANTVFGLGFSSEQQL 96
YD T YR +S +S+ TP+ + T +S + +R N++ G+ + + +
Sbjct: 675 YDETYQRYRPVST-------SSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGI 727
Query: 97 TKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSS--TQASSVNGTDDEKASH 154
TK E+ E +E K +DK+Q K +E R T S TQ S N + + +
Sbjct: 728 TKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTE 787
Query: 155 AGPANTHLKSEN-DKLKIALTQSAANVKNEINR-----------------EKEKNTQLKR 196
G ++++ + + + T + + + R EK+ +T K+
Sbjct: 788 EGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKK 847
Query: 197 RIEE-------LEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDK 249
E+ L+A+L + EL DL+ Q E Q S LE +R+ + LE +
Sbjct: 848 LYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRS-LLEMEKRERRALERR 906
Query: 250 VRSLKTDIE---ESKYRQRHLKVELKSFLEVL 278
+ ++ +++ + K + LK E + + V+
Sbjct: 907 ISEMEEELKMLPDLKADNQRLKDENGALIRVI 938
Score = 30.4 bits (67), Expect = 2.0
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 21/151 (13%)
Query: 82 ANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQE----------- 130
A G S+ + + EK +E KE K K+K +EK E+ ++ E
Sbjct: 620 AEKTIGRSRSTRTREQENEEKEKEEKE--KQDKEKQEEKKESETSREDEYKQKYSRTYDE 677
Query: 131 -SGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKE 189
R P ST +S+ + S + A++ L N + I S + E RE E
Sbjct: 678 TYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYS-RGITKENEREGE 736
Query: 190 KNTQLKRRIEELEAELREKETELKDLRKQSE 220
K R EE E E + + +++ R+ E
Sbjct: 737 K------REEEKEGEDKSQPKSIRERRRPRE 761
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 50.8 bits (120), Expect = 1e-06
Identities = 61/272 (22%), Positives = 116/272 (42%), Gaps = 39/272 (14%)
Query: 38 YDVTRNSYRIISVDGAKVIINSTITPNMTF-TKTSQKFGQWADSRANTVFGLGFSSEQQL 96
YD T YR +S +S+ TP+ + T +S + +R N++ G+ + + +
Sbjct: 762 YDETYQRYRPVST-------SSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGI 814
Query: 97 TKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSS--TQASSVNGTDDEKASH 154
TK E+ E +E K +DK+Q K +E R T S TQ S N + + +
Sbjct: 815 TKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTE 874
Query: 155 AGPANTHLKSEN-DKLKIALTQSAANVKNEINR-----------------EKEKNTQLKR 196
G ++++ + + + T + + + R EK+ +T K+
Sbjct: 875 EGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKK 934
Query: 197 RIEE-------LEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDK 249
E+ L+A+L + EL DL+ Q E Q S LE +R+ + LE +
Sbjct: 935 LYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRS-LLEMEKRERRALERR 993
Query: 250 VRSLKTDIE---ESKYRQRHLKVELKSFLEVL 278
+ ++ +++ + K + LK E + + V+
Sbjct: 994 ISEMEEELKMLPDLKADNQRLKDENGALIRVI 1025
Score = 30.4 bits (67), Expect = 2.0
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 21/151 (13%)
Query: 82 ANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQE----------- 130
A G S+ + + EK +E KE K K+K +EK E+ ++ E
Sbjct: 707 AEKTIGRSRSTRTREQENEEKEKEEKE--KQDKEKQEEKKESETSREDEYKQKYSRTYDE 764
Query: 131 -SGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKE 189
R P ST +S+ + S + A++ L N + I S + E RE E
Sbjct: 765 TYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYS-RGITKENEREGE 823
Query: 190 KNTQLKRRIEELEAELREKETELKDLRKQSE 220
K R EE E E + + +++ R+ E
Sbjct: 824 K------REEEKEGEDKSQPKSIRERRRPRE 848
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
isoform a [Homo sapiens]
Length = 1030
Score = 50.8 bits (120), Expect = 1e-06
Identities = 61/272 (22%), Positives = 116/272 (42%), Gaps = 39/272 (14%)
Query: 38 YDVTRNSYRIISVDGAKVIINSTITPNMTF-TKTSQKFGQWADSRANTVFGLGFSSEQQL 96
YD T YR +S +S+ TP+ + T +S + +R N++ G+ + + +
Sbjct: 762 YDETYQRYRPVST-------SSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGI 814
Query: 97 TKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSS--TQASSVNGTDDEKASH 154
TK E+ E +E K +DK+Q K +E R T S TQ S N + + +
Sbjct: 815 TKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTE 874
Query: 155 AGPANTHLKSEN-DKLKIALTQSAANVKNEINR-----------------EKEKNTQLKR 196
G ++++ + + + T + + + R EK+ +T K+
Sbjct: 875 EGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKK 934
Query: 197 RIEE-------LEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDK 249
E+ L+A+L + EL DL+ Q E Q S LE +R+ + LE +
Sbjct: 935 LYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRS-LLEMEKRERRALERR 993
Query: 250 VRSLKTDIE---ESKYRQRHLKVELKSFLEVL 278
+ ++ +++ + K + LK E + + V+
Sbjct: 994 ISEMEEELKMLPDLKADNQRLKDENGALIRVI 1025
Score = 30.4 bits (67), Expect = 2.0
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 21/151 (13%)
Query: 82 ANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQE----------- 130
A G S+ + + EK +E KE K K+K +EK E+ ++ E
Sbjct: 707 AEKTIGRSRSTRTREQENEEKEKEEKE--KQDKEKQEEKKESETSREDEYKQKYSRTYDE 764
Query: 131 -SGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKE 189
R P ST +S+ + S + A++ L N + I S + E RE E
Sbjct: 765 TYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYS-RGITKENEREGE 823
Query: 190 KNTQLKRRIEELEAELREKETELKDLRKQSE 220
K R EE E E + + +++ R+ E
Sbjct: 824 K------REEEKEGEDKSQPKSIRERRRPRE 848
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 50.8 bits (120), Expect = 1e-06
Identities = 48/231 (20%), Positives = 100/231 (43%), Gaps = 35/231 (15%)
Query: 92 SEQQLTKFAEKFQEVKEAAKIAK------------------------DKTQEKIETSSNH 127
+E +L K++E ++ +E ++A+ D+ QE++ T+
Sbjct: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
Query: 128 SQESGRETPSSTQASSVNGT----DDEKASHAG---PANTHLKSENDKLKIALTQSAANV 180
+E+ + S + V + D+EK H+ + D+ + + +
Sbjct: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
Query: 181 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQ----LMSECEYVSEKL 236
++++ R +E+ + + ELE EL+ LK L Q+E Q E + +S+KL
Sbjct: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
Query: 237 EAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHD 287
+ AE + E V L+ I++ + + H K E S ++LD + +L++
Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
Score = 32.0 bits (71), Expect = 0.68
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Query: 167 DKLKIALTQSAANVKNEINREKEKNTQLKR---RIEELEAELREKETELK----DLRKQS 219
D +K + + +N ++R ++ K R ++LE EL + +LK +L K S
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
Query: 220 EIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYR 263
E + + E +K AE D +L +++ ++ +++ ++ R
Sbjct: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQER 105
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 50.4 bits (119), Expect = 2e-06
Identities = 49/232 (21%), Positives = 97/232 (41%), Gaps = 41/232 (17%)
Query: 92 SEQQLTKFAEKFQEVKEAAKIAK------------------------DKTQEKIETSSNH 127
+E +L K++E ++ +E ++A+ D+ QE++ T+
Sbjct: 54 TEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQK 113
Query: 128 SQESGRETPSSTQASSV---NGTDDEKASHAGPANT----HLKSENDKLKIALTQSAANV 180
+E+ + S + V DE+ H+ E D+ + + +
Sbjct: 114 LEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVII 173
Query: 181 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQ----LMSECEYVSEKL 236
+ ++ R +E+ + + ELE EL+ LK L Q+E Q E + +++KL
Sbjct: 174 EGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKL 233
Query: 237 EAAERDNQNLEDKVRSLK---TDIEESKYRQRHLKVELKSFLEVLDGKIDDL 285
+ AE + E V L+ D+E+ Y Q K++ K+ E LD ++D+
Sbjct: 234 KEAETRAEFAERSVAKLEKTIDDLEDELYAQ---KLKYKAISEELDHALNDM 282
Score = 32.0 bits (71), Expect = 0.68
Identities = 25/114 (21%), Positives = 51/114 (44%), Gaps = 3/114 (2%)
Query: 179 NVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEA 238
N + + + + Q + R ++LE EL + +LK + + + + + + EKLE
Sbjct: 18 NALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQ---EKLEL 74
Query: 239 AERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGL 292
AE+ + E +V SL I+ + + L + L+ L+ + RG+
Sbjct: 75 AEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 128
>gi|157502225 Janus kinase and microtubule interacting protein 3
[Homo sapiens]
Length = 844
Score = 50.1 bits (118), Expect = 2e-06
Identities = 42/192 (21%), Positives = 93/192 (48%), Gaps = 17/192 (8%)
Query: 107 KEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSEN 166
K+ K+AK +ET + +E+ E+ S+ + + TD + + E
Sbjct: 438 KQRKKMAKLPKPVVVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEGMAKEE 497
Query: 167 DKLKI--------ALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQ 218
+L+ AL ++ A ++ ++ + ++K R E+L+AE++ + ++DL K
Sbjct: 498 TELRFRQLTMEYQALQRAYALLQEQVGGTLDAEREVKTR-EQLQAEVQRAQARIEDLEK- 555
Query: 219 SEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVL 278
+ + + +++ EK +A R NQ L +K++ ++T+ + R RH + + E+L
Sbjct: 556 --ALAEQGQDMKWIEEK-QALYRRNQELVEKIKQMETE----EARLRHEVQDARDQNELL 608
Query: 279 DGKIDDLHDFRR 290
+ +I +L + R
Sbjct: 609 EFRILELEERER 620
Score = 38.5 bits (88), Expect = 0.007
Identities = 28/96 (29%), Positives = 52/96 (54%), Gaps = 7/96 (7%)
Query: 158 ANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELE----AELREKETELK 213
AN H+ L AL Q A E+ E+E+ +LK +E+ + +ELRE++ ++
Sbjct: 736 ANKHILELEAMLYDALQQEAGAKVAELLSEEERE-KLKVAVEQWKRQVMSELRERDAQI- 793
Query: 214 DLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDK 249
LR++ E++ + + E++EA +R + LE+K
Sbjct: 794 -LRERMELLQLAQQRIKELEERIEAQKRQIKELEEK 828
Score = 30.4 bits (67), Expect = 2.0
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 29/195 (14%)
Query: 100 AEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSST---QASSVNGTDDEKASHAG 156
A++ Q KEA D+ ++ + H RE P + AS +G+ +++
Sbjct: 236 AQRLQLQKEAL----DEQLSQVREADRHPGSPRRELPHAAGAGDASDHSGSPEQQLDEKD 291
Query: 157 PANTHLK-SENDKLKIALTQSAANVKNEIN------REKE--------KNTQLKRRIEEL 201
LK +E + L A + E N RE E KN +L R+ E+L
Sbjct: 292 ARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDL 351
Query: 202 EAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESK 261
LR E +LK + +++ ++ + + D E +V LK I E
Sbjct: 352 SHALRRMENKLKFVTQEN---IEMRQRAGIIRRPSSLNDLDQSQDEREVDFLKLQIVE-- 406
Query: 262 YRQRHLKVELKSFLE 276
Q++L EL LE
Sbjct: 407 --QQNLIDELSKTLE 419
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 49.7 bits (117), Expect = 3e-06
Identities = 46/207 (22%), Positives = 92/207 (44%), Gaps = 15/207 (7%)
Query: 92 SEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGT---- 147
+E + + Q V+E D+ QE++ T+ +E+ + S + V +
Sbjct: 81 AEADVASLNRRIQLVEEEL----DRAQERLATALQKLEEAEKAADESERGMKVIESRAQK 136
Query: 148 DDEKASHAG---PANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAE 204
D+EK H+ + D+ + + +++++ R +E+ + + ELE E
Sbjct: 137 DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEE 196
Query: 205 LREKETELKDLRKQSEIIPQ----LMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEES 260
L+ LK L Q+E Q E + +S+KL+ AE + E V L+ I++
Sbjct: 197 LKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDL 256
Query: 261 KYRQRHLKVELKSFLEVLDGKIDDLHD 287
+ + H K E S ++LD + +L++
Sbjct: 257 EEKVAHAKEENLSMHQMLDQTLLELNN 283
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 49.7 bits (117), Expect = 3e-06
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 25/206 (12%)
Query: 81 RANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSN-----HSQESGRET 135
R V L + E++ + Q++++ A ++ E++E + + G ET
Sbjct: 1172 REQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET 1231
Query: 136 PSSTQASSVNGTDDEKASH--------AGPANTHLK-SENDKLKIALTQSAANVKNEIN- 185
+ A V KA A H K SE D+L++ L + A+ ++NE++
Sbjct: 1232 DNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDN 1291
Query: 186 ------REKEKNTQLKRRIEELEAELREKETELKDLRKQ----SEIIPQLMSECEYVSEK 235
++K + + LE++L++ + L++ +Q S I QL E + E+
Sbjct: 1292 VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ 1351
Query: 236 LEAAERDNQNLEDKVRSLKTDIEESK 261
E E +NLE +V +L++ + ++K
Sbjct: 1352 QEEEEEARKNLEKQVLALQSQLADTK 1377
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/198 (17%), Positives = 82/198 (41%), Gaps = 3/198 (1%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKA 152
E +L + K Q++ E I ++ Q + E + + R + + + +
Sbjct: 872 EGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRV 931
Query: 153 SHAGPANTHLKSENDKLKIALTQSAANVKNEINREKE---KNTQLKRRIEELEAELREKE 209
N L++E K++ + + E ++ + + +I+++E E+ E
Sbjct: 932 EEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLE 991
Query: 210 TELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKV 269
+ K+ +++ ++EC + E ++ + +K + +D+EE ++ +
Sbjct: 992 DQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ 1051
Query: 270 ELKSFLEVLDGKIDDLHD 287
EL+ LDG+ DL D
Sbjct: 1052 ELEKAKRKLDGETTDLQD 1069
Score = 43.9 bits (102), Expect = 2e-04
Identities = 42/192 (21%), Positives = 84/192 (43%), Gaps = 10/192 (5%)
Query: 101 EKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTD---DEKASHAGP 157
E +++++ KD +E E ++ + + S + S+ E+ + +
Sbjct: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701
Query: 158 ANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRK 217
A H + E D+L +T SA+ ++ ++ ++ + EELE E E RK
Sbjct: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761
Query: 218 QSEIIPQLMSECEYVSEKLEAAERDN--QNLEDKVRSLKTDIEESKYRQRHLKVELKSFL 275
+ + L E +E+ A + DN Q LE + + LK ++E + +K + K+ +
Sbjct: 1762 TTLQVDTL--NAELAAERSAAQKSDNARQQLERQNKELKAKLQE---LEGAVKSKFKATI 1816
Query: 276 EVLDGKIDDLHD 287
L+ KI L +
Sbjct: 1817 SALEAKIGQLEE 1828
Score = 42.7 bits (99), Expect = 4e-04
Identities = 29/113 (25%), Positives = 64/113 (56%), Gaps = 6/113 (5%)
Query: 183 EINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERD 242
E+ + KEK T+++ +EE+E + ++ E L +Q + +L +E E + +L A +
Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK-- 917
Query: 243 NQNLEDKVRSLKTDIEESKYRQRHL---KVELKSFLEVLDGKIDDLHDFRRGL 292
Q LE+ + L++ +EE + R + L K ++++ ++ L+ ++D+ R+ L
Sbjct: 918 -QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL 969
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/139 (25%), Positives = 65/139 (46%), Gaps = 24/139 (17%)
Query: 164 SENDKLKIALTQSA--ANVKNEINREKEKNTQLKR----RIEELEAELREK--------- 208
+E+ KL++ + A A + ++ E+N + KR ++ ELEAEL ++
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 209 -----ETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDI----EE 259
E +LKDL Q E + E KL+A +D Q ++ R+ + +I +E
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 260 SKYRQRHLKVELKSFLEVL 278
S+ + + L+ E+ E L
Sbjct: 1678 SEKKLKSLEAEILQLQEEL 1696
Score = 40.0 bits (92), Expect = 0.002
Identities = 51/237 (21%), Positives = 97/237 (40%), Gaps = 50/237 (21%)
Query: 97 TKFAEKFQEVKEAAKIA----------------KDKTQEKIETSSNHSQESGRETPSSTQ 140
++ AE+ ++ K AKI ++KT++++E + + G T Q
Sbjct: 1013 SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR--KLDGETTDLQDQ 1070
Query: 141 ASSVNGTDDEKASHAGPANTHLKS-----------ENDKLKIA--LTQSAANVKNEINRE 187
+ + DE L+ +N+ LK+ L A ++ + E
Sbjct: 1071 IAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130
Query: 188 KEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEY-VSEKLEAAERDNQNL 246
K + +++ +L EL +TEL+D + +L ++ E V+E +A E + +N
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH 1190
Query: 247 EDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSK----LGTDN 299
E +++ + RQRH + LE L +++ F+ L K L TDN
Sbjct: 1191 EAQIQDM---------RQRH-----ATALEELSEQLEQAKRFKANLEKNKQGLETDN 1233
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 10/136 (7%)
Query: 162 LKSENDKLKIALT---QSAANVKNE-------INREKEKNTQLKRRIEELEAELREKETE 211
L+ E D L + L Q A+N++ + + EK + + + EAE REKET+
Sbjct: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
Query: 212 LKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVEL 271
L + E + E E +++L A D + +D V ++E+SK E+
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1544
Query: 272 KSFLEVLDGKIDDLHD 287
++ LE L+ ++ D
Sbjct: 1545 RTQLEELEDELQATED 1560
Score = 38.9 bits (89), Expect = 0.006
Identities = 41/193 (21%), Positives = 88/193 (45%), Gaps = 34/193 (17%)
Query: 101 EKFQEVKEAAKIAKDKTQEKI----ETSSNHSQESGRETPSSTQASSVNGTDDEKASHAG 156
+K Q K A+ K +E+I + +S +E + SS ++EKA +
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1026
Query: 157 PANT-----------HLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAEL 205
LK E +K + L ++ + E +++ +L+ +I+EL+ +L
Sbjct: 1027 KIRNKQEVMISDLEERLKKE-EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQL 1085
Query: 206 REKETELKD---------LRKQS--EIIPQLMSECEYVSEKLEA-------AERDNQNLE 247
+KE EL+ L K + +++ +L ++ + E E+ AE+ ++L
Sbjct: 1086 AKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLS 1145
Query: 248 DKVRSLKTDIEES 260
+++ +LKT++E++
Sbjct: 1146 EELEALKTELEDT 1158
Score = 38.9 bits (89), Expect = 0.006
Identities = 47/202 (23%), Positives = 89/202 (44%), Gaps = 30/202 (14%)
Query: 108 EAAKIAKDKTQEKIETSSNHSQESGRETPSSTQA--SSVNGTDDEKASHAGPANTHLKSE 165
+ A++ +D EK S N +++ R+ +A + + T D A+ T + E
Sbjct: 1119 QIAELQEDFESEK--ASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ-ELRTKREQE 1175
Query: 166 NDKLKIALTQSAANVKNEINREKEKN-TQLKRRIEELEAELREK----------ETELKD 214
+LK AL + N + +I ++++ T L+ E+LE R K ET+ K+
Sbjct: 1176 VAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKE 1235
Query: 215 LRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSF 274
L + +++ Q+ +E E+ +KL+A +V+ L + E L+VEL
Sbjct: 1236 LACEVKVLQQVKAESEHKRKKLDA----------QVQELHAKVSEGD----RLRVELAEK 1281
Query: 275 LEVLDGKIDDLHDFRRGLSKLG 296
L ++D++ K G
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKG 1303
Score = 33.1 bits (74), Expect = 0.31
Identities = 47/234 (20%), Positives = 91/234 (38%), Gaps = 50/234 (21%)
Query: 92 SEQQLTKFAEKFQEVKEAAKIAKDKTQE------------------KIETSSNHSQESGR 133
++++L K AE + E +A DK ++ + + +SN ++ +
Sbjct: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
Query: 134 ETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEK--- 190
+ S++ E+ A +++ L AL + A K E R+ ++
Sbjct: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARAL-EEALEAKEEFERQNKQLRA 1511
Query: 191 --------NTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEA---- 238
+ + + ELE R E +++++R Q E + + E +LE
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 239 ---------AERDNQNLEDK------VRSLKTDIEESKYRQRHLKVELKSFLEV 277
RD QN E K VR L+ ++E+ + +QR L V K +E+
Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDER-KQRALAVASKKKMEI 1624
Score = 32.3 bits (72), Expect = 0.52
Identities = 39/185 (21%), Positives = 68/185 (36%), Gaps = 35/185 (18%)
Query: 93 EQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKA 152
E+Q + K QE++ A K T +E +E +++A
Sbjct: 1791 ERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQL----------------EQEA 1834
Query: 153 SHAGPANTHLKSENDKLKIALTQ------SAANVKNEINREKEKNTQLKRRIEELEAELR 206
AN ++ KLK Q A K ++ + + QLKR++EE E E
Sbjct: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEAT 1894
Query: 207 EKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVR---SLKTDIEESKYR 263
+ L++ E + +E E R+ L++++R + S R
Sbjct: 1895 RANASRRKLQR----------ELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRR 1944
Query: 264 QRHLK 268
Q HL+
Sbjct: 1945 QLHLE 1949
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 49.3 bits (116), Expect = 4e-06
Identities = 47/229 (20%), Positives = 98/229 (42%), Gaps = 35/229 (15%)
Query: 92 SEQQLTKFAEKFQEVKEAAKIAK------------------------DKTQEKIETSSNH 127
+E +L K++E ++ +E ++A+ D+ QE++ T+
Sbjct: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
Query: 128 SQESGRETPSSTQASSVNGT----DDEKASHAG---PANTHLKSENDKLKIALTQSAANV 180
+E+ + S + V + D+EK H+ + D+ + + +
Sbjct: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
Query: 181 KNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQ----LMSECEYVSEKL 236
++++ R +E+ + + ELE EL+ LK L Q+E Q E + +S+KL
Sbjct: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
Query: 237 EAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDL 285
+ AE + E V L+ I++ + K++ K+ E LD ++D+
Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 32.0 bits (71), Expect = 0.68
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Query: 167 DKLKIALTQSAANVKNEINREKEKNTQLKR---RIEELEAELREKETELK----DLRKQS 219
D +K + + +N ++R ++ K R ++LE EL + +LK +L K S
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
Query: 220 EIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYR 263
E + + E +K AE D +L +++ ++ +++ ++ R
Sbjct: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQER 105
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 49.3 bits (116), Expect = 4e-06
Identities = 50/197 (25%), Positives = 92/197 (46%), Gaps = 22/197 (11%)
Query: 93 EQQLTKFAEKFQEVK---EAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDD 149
EQQ K E+ ++ EA + ++ + +ET +E +E S S++
Sbjct: 1133 EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQ--SALASAQR 1190
Query: 150 EKASHAGPANTHLKSEND-KLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREK 208
E A+ H K+E++ K ++A + A KN + + L+ + L ++ EK
Sbjct: 1191 ELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLI------SSLEEEVSILNRQVLEK 1244
Query: 209 ETELKDLRK----QSEIIPQL-----MSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEE 259
E E K+L++ +SE +L + + E S AAER + L ++V+SL+ + E+
Sbjct: 1245 EGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSA-LREEVQSLREEAEK 1303
Query: 260 SKYRQRHLKVELKSFLE 276
+ +L+ EL S E
Sbjct: 1304 QRVASENLRQELTSQAE 1320
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/222 (21%), Positives = 103/222 (46%), Gaps = 23/222 (10%)
Query: 87 GLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQE---KIETSSNHSQESGRETPSSTQASS 143
GL EQ + +K Q++KE A+ + Q+ ++ T++ + S RE ++ +
Sbjct: 548 GLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK--Q 605
Query: 144 VNGTDDEKASHAGPANTHLKSEN---DKLKIALTQSAANVKNEINRE-----------KE 189
+ + EKA+ L+ N D + ++TQ A K E++R+ ++
Sbjct: 606 LEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQ-AQREKAELSRKVEELQACVETARQ 664
Query: 190 KNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDK 249
+ + + ++ ELE +LR ++ + + + ++ QL + + + E L+ + +LE++
Sbjct: 665 EQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTK---GSLEEE 721
Query: 250 VRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRG 291
R +EE + LK E +S +E + +L + R G
Sbjct: 722 KRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAG 763
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/177 (22%), Positives = 84/177 (47%), Gaps = 13/177 (7%)
Query: 101 EKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANT 160
++FQE ++ ++ + + +E ++ S QAS V + G +
Sbjct: 1524 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQ 1583
Query: 161 H----LKSENDKLKIALTQ---SAANVKNEINREKEKNTQLKRRIEELEAELREKE---T 210
L+++ ++L+ L+Q +A + K ++ + K K++ +EL+ +LR E
Sbjct: 1584 QEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQK 1643
Query: 211 ELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHL 267
E K+LR ++E +L E + K + AE+ ++L +VRSL+ + + + R L
Sbjct: 1644 ENKELRAEAE---RLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1697
Score = 39.7 bits (91), Expect = 0.003
Identities = 36/184 (19%), Positives = 82/184 (44%), Gaps = 14/184 (7%)
Query: 93 EQQLTKFAEK--FQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDE 150
+Q+ AE+ F+E K+ Q I S +E E S + +
Sbjct: 445 QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEEL--EQASQAHGARLTAQVAS 502
Query: 151 KASHAGPANTHLKSENDKL---KIALTQSAANVKNEINREKEKNTQLKRRIEELEAELRE 207
S N ++ ++ +L K + A + + ++++ + L+ ++E+L + L++
Sbjct: 503 LTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQ 562
Query: 208 KETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHL 267
KE +LK++ ++ E Q ++ + AAE +L ++ +LK E+ +++
Sbjct: 563 KEQQLKEVAEKQEATRQ-----DHAQQLATAAEEREASLRERDAALKQ--LEALEKEKAA 615
Query: 268 KVEL 271
K+E+
Sbjct: 616 KLEI 619
Score = 35.0 bits (79), Expect = 0.080
Identities = 46/211 (21%), Positives = 81/211 (38%), Gaps = 22/211 (10%)
Query: 86 FGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVN 145
F L L + E F + E++ S+ ++ R ASS +
Sbjct: 133 FVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIRFLELQKVASSSS 192
Query: 146 GTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAEL 205
G + S A P L++ +++ +K ++ E+ +ELE EL
Sbjct: 193 GNNFLSGSPASPMGDILQTPQFQMR--------RLKKQLADERSNR-------DELELEL 237
Query: 206 REKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLE---DKVRSLKTDIEESKY 262
E L + Q ++ Q + ++EK A+ + + LE DK SL + E+
Sbjct: 238 AENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLK 297
Query: 263 RQRHLKVELKSFLEVLDGKIDDLHDFRRGLS 293
+ + LK E +D KI+ L + LS
Sbjct: 298 QCQDLKTEKSQ----MDRKINQLSEENGDLS 324
Score = 35.0 bits (79), Expect = 0.080
Identities = 26/127 (20%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 180 VKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEA- 238
V E R +E+ +L ++E+LE RE+ ++++L K+ Q + + ++A
Sbjct: 1519 VLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQ 1578
Query: 239 ---AERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGK---IDDLHDFRRGL 292
++++ Q L+ ++ L+ + + + H K++++ D K +L + R L
Sbjct: 1579 GGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSL 1638
Query: 293 SKLGTDN 299
+L +N
Sbjct: 1639 EQLQKEN 1645
Score = 32.7 bits (73), Expect = 0.40
Identities = 40/182 (21%), Positives = 74/182 (40%), Gaps = 19/182 (10%)
Query: 95 QLTKFAEKFQEVKEAAKIAKDK----TQEKIETSSNHSQESGRETPSSTQASSVNGTDDE 150
+L +FA Q++++A ++ TQE +E + +E N
Sbjct: 326 KLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQG 385
Query: 151 KASHAGPANTHLKSENDKLK---IALTQSAANVKNEINREKEKNTQLKRRIEELEAELRE 207
K S + L+ + K + +K E NTQL+ R+E LE E +
Sbjct: 386 KLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQ 445
Query: 208 KETEL--------KDLRKQSEIIPQLMSECEYVSEKLEAAERDNQ----NLEDKVRSLKT 255
+E +L ++ ++ S +I L S +S+ E E+ +Q L +V SL +
Sbjct: 446 QEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTS 505
Query: 256 DI 257
++
Sbjct: 506 EL 507
Score = 31.6 bits (70), Expect = 0.89
Identities = 19/88 (21%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Query: 173 LTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETELKDLRKQ-SEIIPQLMSECEY 231
L + + +IN+ E+N L ++ E + L++ + L +L ++ S+ + + +
Sbjct: 302 LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQ 361
Query: 232 VSEKLEAAERDNQNLEDKVRSLKTDIEE 259
+ ++L AA +D + LE+K L+ + +
Sbjct: 362 LEKELSAALQDKKCLEEKNEILQGKLSQ 389
Score = 31.2 bits (69), Expect = 1.2
Identities = 33/188 (17%), Positives = 75/188 (39%), Gaps = 7/188 (3%)
Query: 94 QQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKAS 153
Q+ + E+ Q +KE+ K+ K +E+ +++ +E R S +A + + + K
Sbjct: 695 QEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQR-CISELKAETRSLVEQHKRE 753
Query: 154 HAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNTQLKRRIEELEAELREKETEL- 212
+ + ++ A + E+ R + + E E E KE
Sbjct: 754 RKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAW 813
Query: 213 -----KDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHL 267
+++++ + + E+ E A ++ Q ++KV +++ E RQ++
Sbjct: 814 RERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNE 873
Query: 268 KVELKSFL 275
EL + L
Sbjct: 874 LAELHANL 881
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.124 0.331
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,713,365
Number of Sequences: 37866
Number of extensions: 395923
Number of successful extensions: 7941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 429
Number of HSP's successfully gapped in prelim test: 933
Number of HSP's that attempted gapping in prelim test: 3554
Number of HSP's gapped (non-prelim): 3835
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.