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Search of human proteins with 110349761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110349761 NSL1, MIND kinetochore complex component isoform 2
[Homo sapiens]
(213 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110349761 NSL1, MIND kinetochore complex component isoform 2 ... 431 e-121
gi|110349759 NSL1, MIND kinetochore complex component isoform 1 ... 338 3e-93
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot... 33 0.14
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot... 33 0.14
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot... 33 0.14
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote... 33 0.14
gi|223555917 metadherin [Homo sapiens] 31 0.68
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap... 30 1.5
gi|117968353 NUF2, NDC80 kinetochore complex component [Homo sap... 30 1.5
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 30 1.5
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 30 1.5
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 30 2.0
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 30 2.0
gi|38524622 formin binding protein 1 [Homo sapiens] 29 2.6
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 29 3.4
gi|24308223 hypothetical protein LOC57577 [Homo sapiens] 28 4.4
gi|46410931 attractin-like 1 [Homo sapiens] 28 5.8
gi|21450863 attractin isoform 2 [Homo sapiens] 28 7.6
gi|21450861 attractin isoform 1 [Homo sapiens] 28 7.6
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 28 7.6
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens] 27 9.9
>gi|110349761 NSL1, MIND kinetochore complex component isoform 2
[Homo sapiens]
Length = 213
Score = 431 bits (1109), Expect = e-121
Identities = 213/213 (100%), Positives = 213/213 (100%)
Query: 1 MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60
MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL
Sbjct: 1 MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60
Query: 61 GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120
GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV
Sbjct: 61 GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120
Query: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPVLNGNAFNFSPFNM 180
DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPVLNGNAFNFSPFNM
Sbjct: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPVLNGNAFNFSPFNM 180
Query: 181 MLAVDLSYMVFITSSPSYGKFEMQRGNSSKGDQ 213
MLAVDLSYMVFITSSPSYGKFEMQRGNSSKGDQ
Sbjct: 181 MLAVDLSYMVFITSSPSYGKFEMQRGNSSKGDQ 213
>gi|110349759 NSL1, MIND kinetochore complex component isoform 1
[Homo sapiens]
Length = 281
Score = 338 bits (866), Expect = 3e-93
Identities = 166/166 (100%), Positives = 166/166 (100%)
Query: 1 MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60
MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL
Sbjct: 1 MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60
Query: 61 GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120
GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV
Sbjct: 61 GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120
Query: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDP 166
DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDP
Sbjct: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDP 166
>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
[Homo sapiens]
Length = 432
Score = 33.5 bits (75), Expect = 0.14
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 188 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 235
Query: 137 VIKTIKA 143
+K+IKA
Sbjct: 236 AVKSIKA 242
>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
[Homo sapiens]
Length = 476
Score = 33.5 bits (75), Expect = 0.14
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 232 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 279
Query: 137 VIKTIKA 143
+K+IKA
Sbjct: 280 AVKSIKA 286
>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
[Homo sapiens]
Length = 457
Score = 33.5 bits (75), Expect = 0.14
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 213 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 260
Query: 137 VIKTIKA 143
+K+IKA
Sbjct: 261 AVKSIKA 267
>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
[Homo sapiens]
Length = 501
Score = 33.5 bits (75), Expect = 0.14
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 257 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 304
Query: 137 VIKTIKA 143
+K+IKA
Sbjct: 305 AVKSIKA 311
>gi|223555917 metadherin [Homo sapiens]
Length = 582
Score = 31.2 bits (69), Expect = 0.68
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 75 DAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYP 130
D+ S + EN+++NG W E S + S I E++++ + A KRK P
Sbjct: 266 DSTLQVSSGLNENLTVNGGGWNEKSVK--LSSQISAGEEKWNSVSPASAGKRKTEP 319
>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
sapiens]
Length = 464
Score = 30.0 bits (66), Expect = 1.5
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 108 IKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
+K +++ IVD K K Y K+ + V K A+QE++++Y
Sbjct: 233 LKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKY 276
>gi|117968353 NUF2, NDC80 kinetochore complex component [Homo
sapiens]
Length = 464
Score = 30.0 bits (66), Expect = 1.5
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 108 IKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
+K +++ IVD K K Y K+ + V K A+QE++++Y
Sbjct: 233 LKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKY 276
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 30.0 bits (66), Expect = 1.5
Identities = 27/109 (24%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 68 IREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQ--FDEIIVDIATK 125
I E + D+++ E A +I N Q + N + D D+K E++ F E+++ +
Sbjct: 141 ILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLD 200
Query: 126 RKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPVLNGNAFN 174
R++ L VI T K E+ +++ LD D P + + +N
Sbjct: 201 REETQEHRL-LVIATDGGKPELTGTVQLLINVLDAN-DNAPEFDKSIYN 247
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 30.0 bits (66), Expect = 1.5
Identities = 27/109 (24%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 68 IREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQ--FDEIIVDIATK 125
I E + D+++ E A +I N Q + N + D D+K E++ F E+++ +
Sbjct: 141 ILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLD 200
Query: 126 RKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPVLNGNAFN 174
R++ L VI T K E+ +++ LD D P + + +N
Sbjct: 201 REETQEHRL-LVIATDGGKPELTGTVQLLINVLDAN-DNAPEFDKSIYN 247
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo
sapiens]
Length = 1502
Score = 29.6 bits (65), Expect = 2.0
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 92 GQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
GQ W+E CF V+ED+ + I + A ++ Y R E V K + QE+L ++
Sbjct: 447 GQPWEEVM--CF------VMEDEAYKYITE-ADSKEVYGRHQREIVEKAKEEFQEMLFEH 497
Query: 152 HPVVHPLDLKYDP 164
+ + LDL P
Sbjct: 498 SELFYDLDLNATP 510
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo
sapiens]
Length = 1501
Score = 29.6 bits (65), Expect = 2.0
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 92 GQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
GQ W+E CF V+ED+ + I + A ++ Y R E V K + QE+L ++
Sbjct: 447 GQPWEEVM--CF------VMEDEAYKYITE-ADSKEVYGRHQREIVEKAKEEFQEMLFEH 497
Query: 152 HPVVHPLDLKYDP 164
+ + LDL P
Sbjct: 498 SELFYDLDLNATP 510
>gi|38524622 formin binding protein 1 [Homo sapiens]
Length = 617
Score = 29.3 bits (64), Expect = 2.6
Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 5/54 (9%)
Query: 111 LEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDP 164
L DQFD + K Q+ ILE IK +K + EI Y + L KY P
Sbjct: 7 LWDQFDNL-----EKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQP 55
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 28.9 bits (63), Expect = 3.4
Identities = 36/159 (22%), Positives = 65/159 (40%), Gaps = 20/159 (12%)
Query: 63 ALPEEIREPALRDAQWTFESAVQENISINGQAWQEASD-----------------NCFMD 105
A+P + PAL D Q T AV+ IS+ Q +S+ N D
Sbjct: 1017 AIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSNEDSD 1076
Query: 106 SDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPD 165
SD+++ E++ + + +IA+ P + + K + +EI+K V+ + +
Sbjct: 1077 SDVEMGENELQDTL-EIASVNLPIPVQ-TKNYYKNVSENKEIVKLV-SVLSTIINSTKKE 1133
Query: 166 PVLNGNAFNFSPFNMMLAVDLSYMVFITSSPSYGKFEMQ 204
+ + + F + + FIT SP +FE Q
Sbjct: 1134 VITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQ 1172
>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
Length = 936
Score = 28.5 bits (62), Expect = 4.4
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 114 QFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPVLNGNAF 173
Q I+ D K+ RK+ E +I+T K Q+ K+Y H L L + + G A
Sbjct: 292 QSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDH---RIKLGKAG 348
Query: 174 NFSPFNMMLAV 184
S + + L V
Sbjct: 349 TLSDWKIQLKV 359
>gi|46410931 attractin-like 1 [Homo sapiens]
Length = 1379
Score = 28.1 bits (61), Expect = 5.8
Identities = 12/36 (33%), Positives = 20/36 (55%)
Query: 167 VLNGNAFNFSPFNMMLAVDLSYMVFITSSPSYGKFE 202
V+ G FN+S F M+L +L ++ +PS G +
Sbjct: 319 VIGGYTFNYSSFQMVLNYNLESSIWNVGTPSRGPLQ 354
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 27.7 bits (60), Expect = 7.6
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 167 VLNGNAFNFSPFNMMLAVDLSYMVFITSSPSYGKFEMQRGNS 208
V+ G FN S +NM+LA DL+ ++ + S ++ G+S
Sbjct: 355 VVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHS 396
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 27.7 bits (60), Expect = 7.6
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 167 VLNGNAFNFSPFNMMLAVDLSYMVFITSSPSYGKFEMQRGNS 208
V+ G FN S +NM+LA DL+ ++ + S ++ G+S
Sbjct: 355 VVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHS 396
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 27.7 bits (60), Expect = 7.6
Identities = 11/36 (30%), Positives = 21/36 (58%)
Query: 177 PFNMMLAVDLSYMVFITSSPSYGKFEMQRGNSSKGD 212
P ++ V+LSY++ T+ P ++ R ++S GD
Sbjct: 853 PAEPLITVELSYIINGTTDPHCASWDYSRADASSGD 888
>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
Length = 885
Score = 27.3 bits (59), Expect = 9.9
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 118 IIVDIATKR-KQYPRKILECVIKTIKAKQEILKQYHP--VVHPLDLKYDP 164
I ++IA KR K RK ++ + ++ L+QYHP + PL+L DP
Sbjct: 831 IFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQQYHPTDITGPLNLS-DP 879
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,294,905
Number of Sequences: 37866
Number of extensions: 340433
Number of successful extensions: 787
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 773
Number of HSP's gapped (non-prelim): 22
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.