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Search of human proteins with 11034811
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11034811 catenin (cadherin-associated protein), delta 2
(neural plakophilin-related arm-repeat protein) [Homo sapiens]
(1225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 2461 0.0
gi|53829374 plakophilin 4 isoform a [Homo sapiens] 1080 0.0
gi|53829376 plakophilin 4 isoform b [Homo sapiens] 1054 0.0
gi|4502247 armadillo repeat protein [Homo sapiens] 488 e-137
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] 475 e-133
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] 475 e-133
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] 475 e-133
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens] 475 e-133
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens] 475 e-133
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens] 475 e-133
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens] 475 e-133
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens] 475 e-133
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] 474 e-133
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens] 474 e-133
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens] 472 e-133
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens] 472 e-133
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens] 472 e-133
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens] 300 7e-81
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens] 278 2e-74
gi|6005830 plakophilin 3 [Homo sapiens] 272 2e-72
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens] 263 6e-70
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ... 263 6e-70
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens] 251 3e-66
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 65 4e-10
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 65 4e-10
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 65 4e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 5e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 3e-09
gi|55750053 atrophin-1 [Homo sapiens] 61 7e-09
gi|55750041 atrophin-1 [Homo sapiens] 61 7e-09
>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
plakophilin-related arm-repeat protein) [Homo sapiens]
Length = 1225
Score = 2461 bits (6377), Expect = 0.0
Identities = 1225/1225 (100%), Positives = 1225/1225 (100%)
Query: 1 MFARKPPGAAPLGAMPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQEL 60
MFARKPPGAAPLGAMPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQEL
Sbjct: 1 MFARKPPGAAPLGAMPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQEL 60
Query: 61 QFERLTRELEAERQIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKDIEDELTTG 120
QFERLTRELEAERQIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKDIEDELTTG
Sbjct: 61 QFERLTRELEAERQIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKDIEDELTTG 120
Query: 121 LELVDSCIRSLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLAL 180
LELVDSCIRSLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLAL
Sbjct: 121 LELVDSCIRSLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLAL 180
Query: 181 GETTPSQLPARGTQARATGQSFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHL 240
GETTPSQLPARGTQARATGQSFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHL
Sbjct: 181 GETTPSQLPARGTQARATGQSFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHL 240
Query: 241 PDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATYAAPRGSSP 300
PDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATYAAPRGSSP
Sbjct: 241 PDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATYAAPRGSSP 300
Query: 301 KQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLS 360
KQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLS
Sbjct: 301 KQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLS 360
Query: 361 PTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHI 420
PTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHI
Sbjct: 361 PTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHI 420
Query: 421 DPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQN 480
DPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQN
Sbjct: 421 DPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQN 480
Query: 481 AAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLARSPSIDSIQK 540
AAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLARSPSIDSIQK
Sbjct: 481 AAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLARSPSIDSIQK 540
Query: 541 DPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDL 600
DPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDL
Sbjct: 541 DPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDL 600
Query: 601 LDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGV 660
LDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGV
Sbjct: 601 LDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGV 660
Query: 661 LWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLR 720
LWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLR
Sbjct: 661 LWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLR 720
Query: 721 NVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETS 780
NVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETS
Sbjct: 721 NVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETS 780
Query: 781 QGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQM 840
QGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQM
Sbjct: 781 QGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQM 840
Query: 841 LWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAVRKEKGLPILVEL 900
LWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAVRKEKGLPILVEL
Sbjct: 841 LWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAVRKEKGLPILVEL 900
Query: 901 LRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTV 960
LRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTV
Sbjct: 901 LRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTV 960
Query: 961 TAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYR 1020
TAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYR
Sbjct: 961 TAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYR 1020
Query: 1021 DLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREM 1080
DLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREM
Sbjct: 1021 DLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREM 1080
Query: 1081 ISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYRNSYGAPAEDIKHNQV 1140
ISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYRNSYGAPAEDIKHNQV
Sbjct: 1081 ISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYRNSYGAPAEDIKHNQV 1140
Query: 1141 SAQPVPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDF 1200
SAQPVPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDF
Sbjct: 1141 SAQPVPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDF 1200
Query: 1201 YSAARPYSELNYETSHYPASPDSWV 1225
YSAARPYSELNYETSHYPASPDSWV
Sbjct: 1201 YSAARPYSELNYETSHYPASPDSWV 1225
>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
Length = 1192
Score = 1080 bits (2792), Expect = 0.0
Identities = 615/1241 (49%), Positives = 809/1241 (65%), Gaps = 79/1241 (6%)
Query: 15 MPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSA-ILASVKEQELQFERLTRELEAER 73
MP P+Q S E S G G E ETT+ ILASVKEQELQF+RLTRELE ER
Sbjct: 1 MPAPEQASLVEEGQPQTRQEA-ASTGPGMEPETTATTILASVKEQELQFQRLTRELEVER 59
Query: 74 QIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKD--IEDELTTGLELVDSCIRSL 131
QIVASQLERC+LG+E+ S++S SS E+ F W+S D + ++ ++ + IR+
Sbjct: 60 QIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTE 119
Query: 132 QESGIL-DPQDYSTGERPSLL--SQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQL 188
E G L P+ S E L S+S+ Q+NS + +Q S+H++Q ++ +
Sbjct: 120 PEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHS 179
Query: 189 PARGTQ------ARATGQSFSQ-GTTSRAGHLAGPEPAPPPPP---------PPREPFAP 232
T +RA GQ+ Q +RA P+ P P R
Sbjct: 180 FIGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRT 239
Query: 233 SLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATY 292
SLGS F P YSS+TLPA R SP + + SPT ++R GS T
Sbjct: 240 SLGSGFGSPSVTDPRPLNPSAYSSTTLPAA-RAASPYSQ-RPASPTAIRRIGSVTSRQT- 296
Query: 293 AAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSST 352
+ P G +P+ + S T + V+S + +SP +S +++ P H
Sbjct: 297 SNPNGPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPK--RSGMTAVPQH----- 349
Query: 353 IGTYATLSPT-KRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELR 411
L P+ +R VH EQ+ + ++Y RP SL G R+SY+SQH LG +LR
Sbjct: 350 ------LGPSLQRTVHDMEQFGQQQYDIYERMVPPRPDSLT-GLRSSYASQHSQLGQDLR 402
Query: 412 ALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQR 471
+ SP+ HI PIYE R Y P RS + + L + T YRT S G+ + LQR
Sbjct: 403 SAVSPDLHITPIYEGRTYYSPVYRSPNHGTVE-LQGSQTALYRTG----SVGIGN--LQR 455
Query: 472 TGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLAR 531
T SQ + T+QR +YA + YA+PYR +QY E Y++ A+P + R
Sbjct: 456 TSSQR-----STLTYQRNNYALNTTATYAEPYRPIQYRVQ-ECNYNRLQHAVPADDGTTR 509
Query: 532 SPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQ 591
SPSIDSIQKDPREF WRDPELPEVI MLQHQFPSVQ+NAAAYLQHLCFGDNK+K E+ R
Sbjct: 510 SPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRL 569
Query: 592 GGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDL 651
GGI+ LVDLLDHR+ EV ++ACGALRNLV+GK+ D+NKIA+KN GGIPAL+RLLRK+ D
Sbjct: 570 GGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDA 629
Query: 652 EIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQV 711
E+RELVTGVLWNLSSCDA+KM II+DAL+ LTN VI+PHSGW NS DD KI+ +S V
Sbjct: 630 EVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLV 689
Query: 712 LRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNL 771
LRN TGCLRN+SSAGEEAR++MR C+GL D+LLYVI + + +S+ DSKTVENCVC LRNL
Sbjct: 690 LRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNL 749
Query: 772 SYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKK---SQDQWDGVGPL 828
SYRL E Q + +G +ELD LL E+ KD+E S CWGKKKKKKK +DQWDGVGP+
Sbjct: 750 SYRLELEVPQARLLGLNELDDLLGKESPSKDSEPS-CWGKKKKKKKRTPQEDQWDGVGPI 808
Query: 829 PDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAV 888
P ++ PKG++MLWHPS+VKPYLTLL+E SNP TLEG+AG+LQNL+AG+WK++ YIRAAV
Sbjct: 809 PGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV 868
Query: 889 RKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSN 948
RKEKGLPILVELLR+DNDRVV +VATALRNMALDVRNKELIGKYAMRDLV+RLPGGN +
Sbjct: 869 RKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPS 928
Query: 949 NTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKA 1008
+SD+T+ A+CC LHEV +KNMENAKAL D+GGIEKLV I+K +GD+ S KVVKA
Sbjct: 929 -----VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKA 983
Query: 1009 ASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNN 1068
A+QVLN++WQYRDLRS+YKKDGW+Q HF+ ST+ERDR + + S T + ++SP
Sbjct: 984 AAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTN---QQMSPII 1040
Query: 1069 RSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYRNSY 1128
+S + +S ++ +++ +++Y+ T Y+ ++G+ T + + ++ S +Y +SY
Sbjct: 1041 QSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATHK--GLYPGSSKPSPIYISSY 1098
Query: 1129 GAPAED----IKHNQVSAQPVPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASE 1184
+PA + ++H Q+ + +RK+++ Y+ + S +Y++ +F+D+VH P +++
Sbjct: 1099 SSPAREQNRRLQHQQLYYS--QDDSNRKNFDAYRLYLQSPHSYEDPYFDDRVHF-PASTD 1155
Query: 1185 YTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV 1225
Y+ GLKST NYVDFYS RP +Y YP SPDSWV
Sbjct: 1156 YSTQYGLKSTTNYVDFYSTKRP----SYRAEQYPGSPDSWV 1192
>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
Length = 1149
Score = 1054 bits (2725), Expect = 0.0
Identities = 611/1241 (49%), Positives = 787/1241 (63%), Gaps = 122/1241 (9%)
Query: 15 MPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSA-ILASVKEQELQFERLTRELEAER 73
MP P+Q S E S G G E ETT+ ILASVKEQELQF+RLTRELE ER
Sbjct: 1 MPAPEQASLVEEGQPQTRQEA-ASTGPGMEPETTATTILASVKEQELQFQRLTRELEVER 59
Query: 74 QIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKD--IEDELTTGLELVDSCIRSL 131
QIVASQLERC+LG+E+ S++S SS E+ F W+S D + ++ ++ + IR+
Sbjct: 60 QIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTE 119
Query: 132 QESGIL-DPQDYSTGERPSLL--SQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQL 188
E G L P+ S E L S+S+ Q+NS + +Q S+H++Q ++ +
Sbjct: 120 PEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHS 179
Query: 189 PARGTQ------ARATGQSFSQ-GTTSRAGHLAGPEPAPPPPP---------PPREPFAP 232
T +RA GQ+ Q +RA P+ P P R
Sbjct: 180 FIGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRT 239
Query: 233 SLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATY 292
SLGS F P YSS+TLPA R SP + + SPT ++R GS T
Sbjct: 240 SLGSGFGSPSVTDPRPLNPSAYSSTTLPAA-RAASPYSQ-RPASPTAIRRIGSVTSRQT- 296
Query: 293 AAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSST 352
+ P G +P+ + S T + V+S + +SP +S +++ P H
Sbjct: 297 SNPNGPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPK--RSGMTAVPQH----- 349
Query: 353 IGTYATLSPT-KRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELR 411
L P+ +R VH EQ+ + ++Y RP SL G R+SY+SQH LG +LR
Sbjct: 350 ------LGPSLQRTVHDMEQFGQQQYDIYERMVPPRPDSLT-GLRSSYASQHSQLGQDLR 402
Query: 412 ALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQR 471
+ SP+ HI PIYE R Y P RS + + L + T YRT S G+ + LQR
Sbjct: 403 SAVSPDLHITPIYEGRTYYSPVYRSPNHGTVE-LQGSQTALYRTG----SVGIGN--LQR 455
Query: 472 TGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLAR 531
T SQ + T+QR +YA + YA+PYR +QY E Y++ A+P + R
Sbjct: 456 TSSQR-----STLTYQRNNYALNTTATYAEPYRPIQYRVQ-ECNYNRLQHAVPADDGTTR 509
Query: 532 SPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQ 591
SPSIDSIQKDPREF WRDPELPEVI MLQHQFPSVQ+NAAAYLQHLCFGDNK+K E+ R
Sbjct: 510 SPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRL 569
Query: 592 GGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDL 651
GGI+ LVDLLDHR+ EV ++ACGALRNLV+GK+ D+NKIA+KN GGIPAL+RLLRK+ D
Sbjct: 570 GGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDA 629
Query: 652 EIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQV 711
E+RELVTGVLWNLSSCDA+KM II+DAL+ LTN VI+PHSGW NS DD KI+ +S V
Sbjct: 630 EVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLV 689
Query: 712 LRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNL 771
LRN TGCLRN+SSAGEEAR++MR C+GL D+LLYVI + + +S+ DSKTVENCVC LRNL
Sbjct: 690 LRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNL 749
Query: 772 SYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKK---SQDQWDGVGPL 828
SYRL E Q + +G +ELD LL E+ KD+E S CWGKKKKKKK +DQWDGVGP+
Sbjct: 750 SYRLELEVPQARLLGLNELDDLLGKESPSKDSEPS-CWGKKKKKKKRTPQEDQWDGVGPI 808
Query: 829 PDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAV 888
P ++ PKG++MLWHPS+VKPYLTLL+E SNP TLEG+AG+LQNL+AG+WK++ YIRAAV
Sbjct: 809 PGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV 868
Query: 889 RKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSN 948
RKEKGLPILVELLR+DNDRVV +VATALRNMALDVRNKELIGKYAMRDLV+RLPGGN +
Sbjct: 869 RKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPS 928
Query: 949 NTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKA 1008
+SD+T+ A+CC LHEV +KNMENAKAL D+GGIEKLV I+K +GD+ S KVVKA
Sbjct: 929 -----VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKA 983
Query: 1009 ASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNN 1068
A+QVLN++WQYRDLRS+YKKDGW+Q HF+ ST+ERDR + + S T + ++SP
Sbjct: 984 AAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTN---QQMSPII 1040
Query: 1069 RSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYRNSY 1128
+S S+ SP +Y +SY
Sbjct: 1041 QSGSSKPSP---------------------------------------------IYISSY 1055
Query: 1129 GAPAED----IKHNQVSAQPVPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASE 1184
+PA + ++H Q+ + +RK+++ Y+ + S +Y++ +F+D+VH P +++
Sbjct: 1056 SSPAREQNRRLQHQQLYYS--QDDSNRKNFDAYRLYLQSPHSYEDPYFDDRVHF-PASTD 1112
Query: 1185 YTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV 1225
Y+ GLKST NYVDFYS RP +Y YP SPDSWV
Sbjct: 1113 YSTQYGLKSTTNYVDFYSTKRP----SYRAEQYPGSPDSWV 1149
>gi|4502247 armadillo repeat protein [Homo sapiens]
Length = 962
Score = 488 bits (1257), Expect = e-137
Identities = 261/524 (49%), Positives = 352/524 (67%), Gaps = 22/524 (4%)
Query: 531 RSPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRR 590
RSPS+DS +K+PR WRDPELPEV+ ML+H V++NAAAYLQHLCF + +K +R+
Sbjct: 342 RSPSVDSARKEPR---WRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQ 398
Query: 591 QGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTD 650
G+ LLV LLDH EV R ACGALRNL YG+ + DNK A+++CGG+PALVRLLR D
Sbjct: 399 LRGLPLLVALLDHPRAEVRRRACGALRNLSYGR-DTDNKAAIRDCGGVPALVRLLRAARD 457
Query: 651 LEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQ 710
E+RELVTG LWNLSS + LKM II L LT+ VI+PHSGWE P +D + +
Sbjct: 458 NEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTT 517
Query: 711 VLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRN 770
V +N +GCLRNVSS G EARRR+REC+GL DALL+ +QSA+G + D+K+VENCVCI+RN
Sbjct: 518 VFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
Query: 771 LSYRLAAETSQGQHMGTDELDGLLCGEANG---KDAESSGCWGKKKKKKK--SQDQWDG- 824
LSY + E E L G A G + + + C+G KK K++ Q + DG
Sbjct: 578 LSYHVHKEVPGADRYQEAEPGPL--GSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGE 635
Query: 825 ------VGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSW 878
LP E KG ++L+ P +V+ YL+LL+E N +TLE AAGALQNL+AG+W
Sbjct: 636 MDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNW 695
Query: 879 KWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLV 938
W+ YIRA VRKE+GLP+LVELL+ + D+VV AVA ALRN++LD RNK+LIG YAM +LV
Sbjct: 696 MWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELV 755
Query: 939 HRLPGGNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKG 998
+ + + +DTV AV T+HE+++ +++NA++L A G+ LV + S
Sbjct: 756 RNVRNAQAPPRPGA-CLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVAS-- 812
Query: 999 DKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSST 1042
S + KAAS VL ++W Y++LR +KDGW++ F ++++T
Sbjct: 813 -SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAAT 855
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/262 (30%), Positives = 99/262 (37%), Gaps = 55/262 (20%)
Query: 47 TTSAILASVKEQELQFERLTRELEAERQIVASQLERCKL-GSETGSMSSMSSAEEQFQWQ 105
+ ++ILASVKEQE +FERLTR LE ER+ VA QLER + G +G M S WQ
Sbjct: 8 SAASILASVKEQEARFERLTRALEQERRHVALQLERAQQPGMVSGGMG--SGQPLPMAWQ 65
Query: 106 SQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTGERPSLLSQ----SALQLNSK 161
L Q+ S G + SL + L+
Sbjct: 66 Q------------------------------LVLQEQSPGSQASLATMPEAPDVLEETVT 95
Query: 162 PEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSFSQGTTSRAGHLAGPEPAP- 220
E P S+ S T G T ++ T T ++ Q GP+ P
Sbjct: 96 VEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVP-------VGPDGLPL 148
Query: 221 PPPPPPREPFAP-SLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTK 279
PP PFA +L F L P A + Y SS P G P +P GS
Sbjct: 149 LDGGPPLGPFADGALDRHFLLRGGGPVATLSRAYLSSG--GGFPEGPEPRDSPSYGS--- 203
Query: 280 LQRG-GSAPEGATYAAPRGSSP 300
L RG G P A P G P
Sbjct: 204 LSRGLGMRP---PRAGPLGPGP 222
>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 244 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 300
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 301 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 359
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 360 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 419
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 420 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 479
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 480 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 595 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 654
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 655 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 709
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 710 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 765
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 766 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 811
>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 244 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 300
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 301 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 359
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 360 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 419
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 420 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 479
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 480 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 595 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 654
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 655 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 709
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 710 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 765
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 766 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 811
>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 244 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 300
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 301 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 359
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 360 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 419
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 420 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 479
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 480 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 595 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 654
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 655 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 709
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 710 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 765
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 766 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 811
>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
Length = 861
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 244 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 300
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 301 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 359
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 360 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 419
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 420 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 479
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 480 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 595 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 654
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 655 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 709
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 710 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 765
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 766 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 811
>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 345 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 401
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 402 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 460
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 461 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 580
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 581 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 696 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 755
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 756 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 810
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 811 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 866
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 867 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 912
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Query: 41 DGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLG-SETGSMSSMSSAE 99
D SE E+T++ILASVKEQE QFE+LTR LE ER+ V++QLER ++ + + + +
Sbjct: 2 DDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLT 61
Query: 100 EQFQWQSQDGQKDIEDELTTGLEL 123
+ Q G D+E + + L+L
Sbjct: 62 RRHQNGRFVGDADLERQKFSDLKL 85
>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 345 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 401
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 402 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 460
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 461 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 580
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 581 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 696 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 755
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 756 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 810
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 811 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 866
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 867 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 912
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Query: 41 DGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLG-SETGSMSSMSSAE 99
D SE E+T++ILASVKEQE QFE+LTR LE ER+ V++QLER ++ + + + +
Sbjct: 2 DDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLT 61
Query: 100 EQFQWQSQDGQKDIEDELTTGLEL 123
+ Q G D+E + + L+L
Sbjct: 62 RRHQNGRFVGDADLERQKFSDLKL 85
>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 345 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 401
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 402 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 460
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 461 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 580
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 581 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 696 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 755
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 756 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 810
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 811 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 866
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 867 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 912
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Query: 41 DGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLG-SETGSMSSMSSAE 99
D SE E+T++ILASVKEQE QFE+LTR LE ER+ V++QLER ++ + + + +
Sbjct: 2 DDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLT 61
Query: 100 EQFQWQSQDGQKDIEDELTTGLEL 123
+ Q G D+E + + L+L
Sbjct: 62 RRHQNGRFVGDADLERQKFSDLKL 85
>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
Length = 962
Score = 475 bits (1222), Expect = e-133
Identities = 262/588 (44%), Positives = 373/588 (63%), Gaps = 23/588 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 345 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 401
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 402 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 460
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 461 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 580
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 581 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 696 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 755
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 756 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 810
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVR 1063
K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S S P+
Sbjct: 811 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDDSTLPL- 866
Query: 1064 VSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
+ N +S P RE I + ++ + +N + +G+H D
Sbjct: 867 IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 912
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Query: 41 DGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLG-SETGSMSSMSSAE 99
D SE E+T++ILASVKEQE QFE+LTR LE ER+ V++QLER ++ + + + +
Sbjct: 2 DDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLT 61
Query: 100 EQFQWQSQDGQKDIEDELTTGLEL 123
+ Q G D+E + + L+L
Sbjct: 62 RRHQNGRFVGDADLERQKFSDLKL 85
>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
Length = 840
Score = 474 bits (1219), Expect = e-133
Identities = 256/548 (46%), Positives = 357/548 (65%), Gaps = 18/548 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 244 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 300
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 301 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 359
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 360 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 419
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 420 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 479
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 480 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 595 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 654
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 655 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 709
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDR-QRPYSSSRTPSISPV 1062
K V+AA+ VL ++W Y++LR +K+GW + F + + R + Y S P I
Sbjct: 710 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRN 769
Query: 1063 RVSPNNRS 1070
+ S NN S
Sbjct: 770 QKSDNNYS 777
>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
Length = 941
Score = 474 bits (1219), Expect = e-133
Identities = 256/548 (46%), Positives = 357/548 (65%), Gaps = 18/548 (3%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 345 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 401
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 402 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 460
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 461 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 580
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKS--QDQWD 823
C+LRNLSY++ E Q + AN ++ C+G KK K K +D +
Sbjct: 581 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 824 GVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVY 883
P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG W + Y
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 884 IRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPG 943
IR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +LV LPG
Sbjct: 696 IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 755
Query: 944 GNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSP 1003
G + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS S
Sbjct: 756 GQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS--GNRSE 810
Query: 1004 KVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDR-QRPYSSSRTPSISPV 1062
K V+AA+ VL ++W Y++LR +K+GW + F + + R + Y S P I
Sbjct: 811 KEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRN 870
Query: 1063 RVSPNNRS 1070
+ S NN S
Sbjct: 871 QKSDNNYS 878
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Query: 41 DGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLG-SETGSMSSMSSAE 99
D SE E+T++ILASVKEQE QFE+LTR LE ER+ V++QLER ++ + + + +
Sbjct: 2 DDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLT 61
Query: 100 EQFQWQSQDGQKDIEDELTTGLEL 123
+ Q G D+E + + L+L
Sbjct: 62 RRHQNGRFVGDADLERQKFSDLKL 85
>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
Length = 838
Score = 472 bits (1215), Expect = e-133
Identities = 262/594 (44%), Positives = 373/594 (62%), Gaps = 29/594 (4%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 244 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 300
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 301 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 359
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 360 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 419
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 420 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 479
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKK--------KKKK 817
C+LRNLSY++ E Q + AN ++ C+G KK KK
Sbjct: 480 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKP 534
Query: 818 SQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGS 877
+D + P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG
Sbjct: 535 IEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGR 594
Query: 878 WKWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDL 937
W + YIR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +L
Sbjct: 595 WTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNL 654
Query: 938 VHRLPGGNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSK 997
V LPGG + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS
Sbjct: 655 VKNLPGGQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS- 710
Query: 998 GDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTP 1057
S K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S
Sbjct: 711 -GNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDD 766
Query: 1058 SISPVRVSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
S P+ + N +S P RE I + ++ + +N + +G+H D
Sbjct: 767 STLPL-IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 817
>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
Length = 867
Score = 472 bits (1215), Expect = e-133
Identities = 262/594 (44%), Positives = 373/594 (62%), Gaps = 29/594 (4%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 244 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 300
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 301 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 359
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 360 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 419
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 420 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 479
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKK--------KKKK 817
C+LRNLSY++ E Q + AN ++ C+G KK KK
Sbjct: 480 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKP 534
Query: 818 SQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGS 877
+D + P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG
Sbjct: 535 IEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGR 594
Query: 878 WKWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDL 937
W + YIR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +L
Sbjct: 595 WTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNL 654
Query: 938 VHRLPGGNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSK 997
V LPGG + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS
Sbjct: 655 VKNLPGGQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS- 710
Query: 998 GDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTP 1057
S K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S
Sbjct: 711 -GNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDD 766
Query: 1058 SISPVRVSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
S P+ + N +S P RE I + ++ + +N + +G+H D
Sbjct: 767 STLPL-IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 817
>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
Length = 968
Score = 472 bits (1215), Expect = e-133
Identities = 262/594 (44%), Positives = 373/594 (62%), Gaps = 29/594 (4%)
Query: 527 GTLARSPSIDSIQKD-PREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIK 585
G+LA S+DS++K P WR PELPEVI ML + +V+SNAAAYLQHLC+ ++K+K
Sbjct: 345 GSLA---SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVK 401
Query: 586 AEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
++R+ GI +LV LLDH EVH ACGAL+N+ +G+ + DNKIA+KNC G+PALVRLL
Sbjct: 402 TDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGR-DQDNKIAIKNCDGVPALVRLL 460
Query: 646 RKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ 705
RK D+++ E++TG LWNLSS D++KM I+ AL LT+ VIIPHSGWE P +D +
Sbjct: 461 RKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520
Query: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
+ VL N GCLRNVSS EARR++RECDGL DAL++++Q+ +G + DSK VENCV
Sbjct: 521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCV 580
Query: 766 CILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKK--------KKKK 817
C+LRNLSY++ E Q + AN ++ C+G KK KK
Sbjct: 581 CLLRNLSYQVHREIPQ-----AERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKP 635
Query: 818 SQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGS 877
+D + P P +G ++L+ P +V+ Y++LL E P LE +AGA+QNL AG
Sbjct: 636 IEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGR 695
Query: 878 WKWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDL 937
W + YIR+A+R+EK L + +LL +++RVV A + ALRN+A+D RNKELIGK+A+ +L
Sbjct: 696 WTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNL 755
Query: 938 VHRLPGGNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSK 997
V LPGG + +S S+DTV ++ T++EVI +N+E AK LR+ GIEKLV I+KS
Sbjct: 756 VKNLPGGQQN---SSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS- 811
Query: 998 GDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTP 1057
S K V+AA+ VL ++W Y++LR +K+GW + F + + R + S S
Sbjct: 812 -GNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQS---SHSYDD 867
Query: 1058 SISPVRVSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKD 1111
S P+ + N +S P RE I + ++ + +N + +G+H D
Sbjct: 868 STLPL-IDRNQKSDKKP--DREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLD 918
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Query: 41 DGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLG-SETGSMSSMSSAE 99
D SE E+T++ILASVKEQE QFE+LTR LE ER+ V++QLER ++ + + + +
Sbjct: 2 DDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLT 61
Query: 100 EQFQWQSQDGQKDIEDELTTGLEL 123
+ Q G D+E + + L+L
Sbjct: 62 RRHQNGRFVGDADLERQKFSDLKL 85
>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
Length = 837
Score = 300 bits (767), Expect = 7e-81
Identities = 223/695 (32%), Positives = 343/695 (49%), Gaps = 53/695 (7%)
Query: 367 HASEQYSK--------HSQELYATATLQRP----GSLAAGSRASYSSQHGHLGPELRALQ 414
H+ QYS+ H QE A L P + SRA +S+ H R Q
Sbjct: 163 HSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQ 222
Query: 415 S---PEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQR 471
+ D I + P S+S G+ L + T + P V P+ +
Sbjct: 223 HGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQ 282
Query: 472 TGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLAR 531
+ + ++ R AGP S D + + ++ SG L T
Sbjct: 283 NRASRSSWHQSSFHSTRTLREAGP-SVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTD 341
Query: 532 SPSIDSIQKDPREFGWRDPE--LPEVIQMLQ--HQFPSVQSNAAAYLQHLCFGDNKIKAE 587
S + G D E L + ML+ H PS S AA ++QH CF ++ +
Sbjct: 342 S-----------QLGNADMEMTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKR 390
Query: 588 IRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRK 647
+ + GI L+ LL + +V R+ CGALRNLV+ ++DNK+ + G+P L+++L++
Sbjct: 391 VNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQ 448
Query: 648 TTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ-L 706
T DLE ++ +TG+LWNLSS D LK +I +AL LT +IIP SGW P D K L
Sbjct: 449 TRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKANGL 505
Query: 707 HSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVC 766
+ N TGCLRN+SSAG + R+ MR CDGL D+L++ ++ + + D K ENCVC
Sbjct: 506 LDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVC 565
Query: 767 ILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVG 826
IL NLSY+L AE + + + + N +S GC+G + +K K Q Q
Sbjct: 566 ILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNN----KSIGCFGSRSRKVKEQYQ---DV 618
Query: 827 PLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYI-R 885
P+P+ PKG++ LWH +++ YL+L+++ T E + GALQNL AGS + +
Sbjct: 619 PMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQ 678
Query: 886 AAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGN 945
V+KE GL ++L + + V + LRN++ ++ + I K + DLV +P
Sbjct: 679 TVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIP--- 735
Query: 946 NSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKH-SPK 1004
+ S + +T + C TL+ +I + +NA+ L + GGI+K++ I S GD + S K
Sbjct: 736 --DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAI--SAGDAYASNK 791
Query: 1005 VVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVAS 1039
KAAS +L S+W + +L YKK + + FV S
Sbjct: 792 ASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVNS 826
>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
Length = 881
Score = 278 bits (712), Expect = 2e-74
Identities = 223/739 (30%), Positives = 343/739 (46%), Gaps = 97/739 (13%)
Query: 367 HASEQYSK--------HSQELYATATLQRP----GSLAAGSRASYSSQHGHLGPELRALQ 414
H+ QYS+ H QE A L P + SRA +S+ H R Q
Sbjct: 163 HSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQ 222
Query: 415 S---PEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQR 471
+ D I + P S+S G+ L + T + P V P+ +
Sbjct: 223 HGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQ 282
Query: 472 TGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLAR 531
+ + ++ R AGP S D + + ++ SG L T
Sbjct: 283 NRASRSSWHQSSFHSTRTLREAGP-SVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTD 341
Query: 532 SPSIDSIQKDPREFGWRDPE--LPEVIQMLQ--HQFPSVQSNAAAYLQHLCFGDNKIKAE 587
S + G D E L + ML+ H PS S AA ++QH CF ++ +
Sbjct: 342 S-----------QLGNADMEMTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKR 390
Query: 588 IRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRK 647
+ + GI L+ LL + +V R+ CGALRNLV+ ++DNK+ + G+P L+++L++
Sbjct: 391 VNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQ 448
Query: 648 TTDLEIRELVT--------------------------------------------GVLWN 663
T DLE ++ +T G+LWN
Sbjct: 449 TRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWN 508
Query: 664 LSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ-LHSSQVLRNATGCLRNV 722
LSS D LK +I +AL LT +IIP SGW P D K L + N TGCLRN+
Sbjct: 509 LSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNM 565
Query: 723 SSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQG 782
SSAG + R+ MR CDGL D+L++ ++ + + D K ENCVCIL NLSY+L AE +
Sbjct: 566 SSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEK 625
Query: 783 QHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLW 842
+ + + N +S GC+G + +K K Q Q P+P+ PKG++ LW
Sbjct: 626 YSQNIYIQNRNIQTDNN----KSIGCFGSRSRKVKEQYQ---DVPMPEEKSNPKGVEWLW 678
Query: 843 HPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYI-RAAVRKEKGLPILVELL 901
H +++ YL+L+++ T E + GALQNL AGS + + V+KE GL ++L
Sbjct: 679 HSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKML 738
Query: 902 RIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVT 961
+ + V + LRN++ ++ + I K + DLV +P + S + +T
Sbjct: 739 HVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIP-----DTVPSTDLLIETTA 793
Query: 962 AVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKH-SPKVVKAASQVLNSMWQYR 1020
+ C TL+ +I + +NA+ L + GGI+K++ I S GD + S K KAAS +L S+W +
Sbjct: 794 SACYTLNNIIQNSYQNARDLLNTGGIQKIMAI--SAGDAYASNKASKAASVLLYSLWAHT 851
Query: 1021 DLRSLYKKDGWSQYHFVAS 1039
+L YKK + + FV S
Sbjct: 852 ELHHAYKKAQFKKTDFVNS 870
>gi|6005830 plakophilin 3 [Homo sapiens]
Length = 797
Score = 272 bits (695), Expect = 2e-72
Identities = 177/501 (35%), Positives = 270/501 (53%), Gaps = 29/501 (5%)
Query: 546 GWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRM 605
G+ D +LP ++ L P++Q AAY+QH C+ D K + R + LV L +H
Sbjct: 315 GFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHAN 374
Query: 606 TEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLS 665
EV R A GA+RNL+Y A DNK+AL GI L+R LR+ D E+R+ VTG+LWNLS
Sbjct: 375 QEVQRHATGAMRNLIYDNA--DNKLALVEENGIFELLRTLREQDD-ELRKNVTGILWNLS 431
Query: 666 SCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQ--VLRNATGCLRNVS 723
S D LK + +D L LT+ V+ P SG PL IQ ++S+ + NATG LRN+S
Sbjct: 432 SSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPL-----IQQNASEAEIFYNATGFLRNLS 486
Query: 724 SAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQG- 782
SA + R++MREC GL DAL+ I AL + + + K+VEN VC+LRNLSYRL E
Sbjct: 487 SASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSA 546
Query: 783 ----QHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGI 838
+ G +L G GE GC+ + ++ + + ++ PKG+
Sbjct: 547 LQRLEGRGRRDLAGAPPGEV-------VGCFTPQSRRLRELPLAADALTFAEVSKDPKGL 599
Query: 839 QMLWHPSIVKPYLTLLSECS-NPDTLEGAAGALQNLAAGSWKWS-VYIRAAVRKEKGLPI 896
+ LW P IV Y LL C N T E AAGALQN+ AG +W+ V R A+ +E+ L
Sbjct: 600 EWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNP 659
Query: 897 LVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMS 956
L++ +R + + ++ +RN++ + RNK+ + + L+ +LPG + K+
Sbjct: 660 LLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPG-----SVGEKSPP 714
Query: 957 DDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSM 1016
+ + + L+ ++ + A+ L G+ KL+ I K + S K +AAS +L ++
Sbjct: 715 AEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANL 774
Query: 1017 WQYRDLRSLYKKDGWSQYHFV 1037
WQY L ++ G+ + F+
Sbjct: 775 WQYNKLHRDFRAKGYRKEDFL 795
>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
Length = 726
Score = 263 bits (673), Expect = 6e-70
Identities = 170/487 (34%), Positives = 261/487 (53%), Gaps = 31/487 (6%)
Query: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611
+P+ +Q L Q Q+ A Y+QH CF D K ++ + GGI LVDLL V ++
Sbjct: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
Query: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671
A GALRNLV+ NK+ + GI V LLR+T + EI++ +TG+LWNLSS D LK
Sbjct: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
Query: 672 MPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARR 731
+I DAL VL + VIIP SGW + R++ +V NATGCLRN+SSA + R+
Sbjct: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREVV--DPEVFFNATGCLRNLSSA-DAGRQ 421
Query: 732 RMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELD 791
MR GL D+L+ +Q+ + +S D K+VENC+C+L NLSYRL AE
Sbjct: 422 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQ------ 475
Query: 792 GLLCGEANGKDA----ESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIV 847
E N ++A S+GC+ K K + + +D PLP+ PKG L+H +
Sbjct: 476 ----LEYNARNAYTEKSSTGCFSNKSDKMMN-NNYD--CPLPEEETNPKGSGWLYHSDAI 528
Query: 848 KPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAV-RKEKGLPILVELLRIDND 906
+ YL L+ + TLE AGALQNL A S + + KEKGLP + LL+ N
Sbjct: 529 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS 588
Query: 907 RVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVTAVCCT 966
VV + A+ L NM+ ++G ++ L +++T + + S+D +++ C T
Sbjct: 589 DVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLL-----TSHTGNTSNSEDILSSACYT 643
Query: 967 LHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLY 1026
+ ++ + AK + + ++ + +S SPK +AA +L+ MW ++L+ +
Sbjct: 644 VRNLMASQPQLAKQYFSSSMLNNIINLCRSSA---SPKAAEAARLLLSDMWSSKELQGVL 700
Query: 1027 KKDGWSQ 1033
++ G+ +
Sbjct: 701 RQQGFDR 707
>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
sapiens]
Length = 625
Score = 263 bits (673), Expect = 6e-70
Identities = 170/487 (34%), Positives = 261/487 (53%), Gaps = 31/487 (6%)
Query: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611
+P+ +Q L Q Q+ A Y+QH CF D K ++ + GGI LVDLL V ++
Sbjct: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
Query: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671
A GALRNLV+ NK+ + GI V LLR+T + EI++ +TG+LWNLSS D LK
Sbjct: 206 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 263
Query: 672 MPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARR 731
+I DAL VL + VIIP SGW + R++ +V NATGCLRN+SSA + R+
Sbjct: 264 EELIADALPVLADRVIIPFSGWCDGNSNMSREVV--DPEVFFNATGCLRNLSSA-DAGRQ 320
Query: 732 RMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELD 791
MR GL D+L+ +Q+ + +S D K+VENC+C+L NLSYRL AE
Sbjct: 321 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQ------ 374
Query: 792 GLLCGEANGKDA----ESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIV 847
E N ++A S+GC+ K K + + +D PLP+ PKG L+H +
Sbjct: 375 ----LEYNARNAYTEKSSTGCFSNKSDKMMN-NNYD--CPLPEEETNPKGSGWLYHSDAI 427
Query: 848 KPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAV-RKEKGLPILVELLRIDND 906
+ YL L+ + TLE AGALQNL A S + + KEKGLP + LL+ N
Sbjct: 428 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS 487
Query: 907 RVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVTAVCCT 966
VV + A+ L NM+ ++G ++ L +++T + + S+D +++ C T
Sbjct: 488 DVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLL-----TSHTGNTSNSEDILSSACYT 542
Query: 967 LHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLY 1026
+ ++ + AK + + ++ + +S SPK +AA +L+ MW ++L+ +
Sbjct: 543 VRNLMASQPQLAKQYFSSSMLNNIINLCRSSA---SPKAAEAARLLLSDMWSSKELQGVL 599
Query: 1027 KKDGWSQ 1033
++ G+ +
Sbjct: 600 RQQGFDR 606
>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
Length = 747
Score = 251 bits (641), Expect = 3e-66
Identities = 170/508 (33%), Positives = 261/508 (51%), Gaps = 52/508 (10%)
Query: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611
+P+ +Q L Q Q+ A Y+QH CF D K ++ + GGI LVDLL V ++
Sbjct: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
Query: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671
A GALRNLV+ NK+ + GI V LLR+T + EI++ +TG+LWNLSS D LK
Sbjct: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
Query: 672 MPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLR----------- 720
+I DAL VL + VIIP SGW + R++ +V NATGCLR
Sbjct: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREVV--DPEVFFNATGCLRKRLGMRELLAL 422
Query: 721 ----------NVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRN 770
N+SSA + R+ MR GL D+L+ +Q+ + +S D K+VENC+C+L N
Sbjct: 423 VPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN 481
Query: 771 LSYRLAAETSQGQHMGTDELDGLLCGEANGKDA----ESSGCWGKKKKKKKSQDQWDGVG 826
LSYRL AE E N ++A S+GC+ K K + + +D
Sbjct: 482 LSYRLDAEVPTRYRQ----------LEYNARNAYTEKSSTGCFSNKSDKMMN-NNYD--C 528
Query: 827 PLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRA 886
PLP+ PKG L+H ++ YL L+ + TLE AGALQNL A S +
Sbjct: 529 PLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQ 588
Query: 887 AV-RKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGN 945
+ KEKGLP + LL+ N VV + A+ L NM+ ++G ++ L
Sbjct: 589 LIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLL---- 644
Query: 946 NSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKV 1005
+++T + + S+D +++ C T+ ++ + AK + + ++ + +S SPK
Sbjct: 645 -TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA---SPKA 700
Query: 1006 VKAASQVLNSMWQYRDLRSLYKKDGWSQ 1033
+AA +L+ MW ++L+ + ++ G+ +
Sbjct: 701 AEAARLLLSDMWSSKELQGVLRQQGFDR 728
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 65.1 bits (157), Expect = 4e-10
Identities = 134/571 (23%), Positives = 202/571 (35%), Gaps = 92/571 (16%)
Query: 20 QPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQ 79
QP+S +TS ++ + +S + +TS+ + + + +++ E A + +++
Sbjct: 37 QPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEE--ASSPLKSNK 94
Query: 80 LERCKLGSETGSMSSMSSAEEQFQWQSQDGQ-----------KDIEDELTTGLELVDSCI 128
+R K+ S+T SS + + Q S+ + + DE ++ + +D
Sbjct: 95 RQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDN 154
Query: 129 RSLQESGILDPQDYSTGERPSLLSQSALQLN----SKPEGSFQYPASYH-SNQTLALGET 183
RS S I PQD + + S Q LQ P G P+S L
Sbjct: 155 RSTSPS-IPSPQD-NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 212
Query: 184 TPSQ--LPARGTQARATGQSFSQGTTSRAGHL-----------AGPEPAPPPPPPPREPF 230
TPS +P +G+ + + Q T+ H P P PPP P P P
Sbjct: 213 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 272
Query: 231 APSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGA 290
P GSA P A P+ A L+ PP S A P P Q G P+ +
Sbjct: 273 QPLTGSAGQ-PSA-PSHAQPPLHGQ-----GPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325
Query: 291 TYAAPRGSSPK--------QSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTIS 342
AP G+SP Q P+ + S P + A L+ + PPT
Sbjct: 326 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT------ 379
Query: 343 SSPIHQL--------------SSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRP 388
+PI QL S A L P L S + H + P
Sbjct: 380 -TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 438
Query: 389 GSLAAGSRASYS---SQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPL 445
S S + +Q +L P P H P +V +PP G P
Sbjct: 439 QSQPLPSSPAQPPGLTQSQNLPP------PPASH-PPTGLHQVAPQPPFAQHPFVPGGPP 491
Query: 446 PPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQ 505
P TST P+ PG + P P + AAA+ S A G + +
Sbjct: 492 PITPPTCPSTSTPPAGPGTSAQP---------PCSGAAAS--GGSIAGGSSCPLPTVQIK 540
Query: 506 LQYCPSVESPYSKSGP--ALPPEGTLARSPS 534
+ E P S P + PE T+ +PS
Sbjct: 541 EEALDDAEEPESPPPPPRSPSPEPTVVDTPS 571
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 65.1 bits (157), Expect = 4e-10
Identities = 134/571 (23%), Positives = 202/571 (35%), Gaps = 92/571 (16%)
Query: 20 QPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQ 79
QP+S +TS ++ + +S + +TS+ + + + +++ E A + +++
Sbjct: 591 QPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEE--ASSPLKSNK 648
Query: 80 LERCKLGSETGSMSSMSSAEEQFQWQSQDGQ-----------KDIEDELTTGLELVDSCI 128
+R K+ S+T SS + + Q S+ + + DE ++ + +D
Sbjct: 649 RQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDN 708
Query: 129 RSLQESGILDPQDYSTGERPSLLSQSALQLN----SKPEGSFQYPASYH-SNQTLALGET 183
RS S I PQD + + S Q LQ P G P+S L
Sbjct: 709 RSTSPS-IPSPQD-NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766
Query: 184 TPSQ--LPARGTQARATGQSFSQGTTSRAGHL-----------AGPEPAPPPPPPPREPF 230
TPS +P +G+ + + Q T+ H P P PPP P P P
Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826
Query: 231 APSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGA 290
P GSA P A P+ A L+ PP S A P P Q G P+ +
Sbjct: 827 QPLTGSAGQ-PSA-PSHAQPPLHGQ-----GPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 879
Query: 291 TYAAPRGSSPK--------QSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTIS 342
AP G+SP Q P+ + S P + A L+ + PPT
Sbjct: 880 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT------ 933
Query: 343 SSPIHQL--------------SSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRP 388
+PI QL S A L P L S + H + P
Sbjct: 934 -TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 992
Query: 389 GSLAAGSRASYS---SQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPL 445
S S + +Q +L P P H P +V +PP G P
Sbjct: 993 QSQPLPSSPAQPPGLTQSQNLPP------PPASH-PPTGLHQVAPQPPFAQHPFVPGGPP 1045
Query: 446 PPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQ 505
P TST P+ PG + P P + AAA+ S A G + +
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQP---------PCSGAAAS--GGSIAGGSSCPLPTVQIK 1094
Query: 506 LQYCPSVESPYSKSGP--ALPPEGTLARSPS 534
+ E P S P + PE T+ +PS
Sbjct: 1095 EEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 65.1 bits (157), Expect = 4e-10
Identities = 134/571 (23%), Positives = 202/571 (35%), Gaps = 92/571 (16%)
Query: 20 QPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQ 79
QP+S +TS ++ + +S + +TS+ + + + +++ E A + +++
Sbjct: 591 QPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEE--ASSPLKSNK 648
Query: 80 LERCKLGSETGSMSSMSSAEEQFQWQSQDGQ-----------KDIEDELTTGLELVDSCI 128
+R K+ S+T SS + + Q S+ + + DE ++ + +D
Sbjct: 649 RQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDN 708
Query: 129 RSLQESGILDPQDYSTGERPSLLSQSALQLN----SKPEGSFQYPASYH-SNQTLALGET 183
RS S I PQD + + S Q LQ P G P+S L
Sbjct: 709 RSTSPS-IPSPQD-NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766
Query: 184 TPSQ--LPARGTQARATGQSFSQGTTSRAGHL-----------AGPEPAPPPPPPPREPF 230
TPS +P +G+ + + Q T+ H P P PPP P P P
Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826
Query: 231 APSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGA 290
P GSA P A P+ A L+ PP S A P P Q G P+ +
Sbjct: 827 QPLTGSAGQ-PSA-PSHAQPPLHGQ-----GPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 879
Query: 291 TYAAPRGSSPK--------QSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTIS 342
AP G+SP Q P+ + S P + A L+ + PPT
Sbjct: 880 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT------ 933
Query: 343 SSPIHQL--------------SSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRP 388
+PI QL S A L P L S + H + P
Sbjct: 934 -TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 992
Query: 389 GSLAAGSRASYS---SQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPL 445
S S + +Q +L P P H P +V +PP G P
Sbjct: 993 QSQPLPSSPAQPPGLTQSQNLPP------PPASH-PPTGLHQVAPQPPFAQHPFVPGGPP 1045
Query: 446 PPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQ 505
P TST P+ PG + P P + AAA+ S A G + +
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQP---------PCSGAAAS--GGSIAGGSSCPLPTVQIK 1094
Query: 506 LQYCPSVESPYSKSGP--ALPPEGTLARSPS 534
+ E P S P + PE T+ +PS
Sbjct: 1095 EEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 64.7 bits (156), Expect = 5e-10
Identities = 104/406 (25%), Positives = 150/406 (36%), Gaps = 75/406 (18%)
Query: 143 STGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSF 202
S E + A + G Q PAS + + TP PAR +G S
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS-----ATPLSSPAR------SGPS- 258
Query: 203 SQGTTSRAGHLAGPEPA------PPPPPPPREPFAPSLGSAFHLPDAPPAAAAAALYYSS 256
++GT H + P+P PP PPR+ AP+LG P A P+ +AA +
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318
Query: 257 STLPAPPRGGS---------PLAAPQGGSPTKLQRGGSAPEGATYAAPRGSSPKQSPSRL 307
TLPA P S PLA P +P LQ T +P + P Q+ + L
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ---------TLPSPPATPPSQATTSL 369
Query: 308 AKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTKRLVH 367
T + + S LSP+ T PP ++ P+ Q + LSP
Sbjct: 370 GS--PTLQATHSFLPSPPLSPL-ATPPPQAPPALALPPL-QAPPSPPASPPLSP------ 419
Query: 368 ASEQYSKHSQELYATATLQRPGSLAAG-SRASYSSQHGHLGPELRALQSPEHHIDPIYED 426
AT + Q P +LA +A +S P ++A SP P+
Sbjct: 420 ------------LATPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFSPPAS-PPVSPS 463
Query: 427 RV--YQKPPMRSLSQSQGDPLPPAHTGTYRTSTAP--SSPGVDSVPLQRTGSQHGPQNAA 482
Q PP + Q P PPA ++T P + P + + PLQ ++ PQ
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL--AKPPPQAPP 521
Query: 483 AATFQRASYAAGPASNYADPYRQLQYCPSVE---SPYSKSGPALPP 525
A P +++ Q + PS SP + P PP
Sbjct: 522 ALATPPLQALPSPPASFPG---QAPFSPSASLPMSPLATPPPQAPP 564
Score = 46.2 bits (108), Expect = 2e-04
Identities = 93/379 (24%), Positives = 134/379 (35%), Gaps = 72/379 (18%)
Query: 196 RATGQSFSQGTTSRAGHLAGPEP--APPPPPP---------------PREPFAPSLG--S 236
+A + ++ +RA L P P +P PPPP R+P A G
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 237 AFHLPDAPPAAAAAALYYSSSTLPA--PPRGGSPLAAP--QGGSPTKLQRGGSAPEGATY 292
+P++ P A +SS PA PP G AP + SP + G A G T
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA-SGTTR 125
Query: 293 AAPRGSSPKQ--SPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLS 350
P G + + +A+ +T +P +S+ R TS PT + S + + S
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR---RDTSGPTPGT--PSPAMARRS 180
Query: 351 STIGTYA--------------TLSPTKRLVHASEQYSKH-----SQELYATATLQRPGSL 391
GT T P K + ASE + + A LQRP S
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 392 AAGSRASYSSQHGHLGPELRAL-QSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHT 450
+ S A+ S GP R ++P H P + +PP + PP
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT---------PP--- 288
Query: 451 GTYRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCP 510
R AP+ + S PL Q+ A T +++ A P P
Sbjct: 289 ---RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP--P 343
Query: 511 SVESPYS----KSGPALPP 525
S +P S S PA PP
Sbjct: 344 SPSAPPSLQTLPSPPATPP 362
Score = 34.7 bits (78), Expect = 0.57
Identities = 41/135 (30%), Positives = 53/135 (39%), Gaps = 17/135 (12%)
Query: 177 TLALGETTPSQLPARGTQARATGQSFSQGTTSRA-------GHLAGPEPAPPPPPPPREP 229
TLAL P P+R + +G + ++S G+ +GPE PPP
Sbjct: 604 TLALAPGPPPP-PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 662
Query: 230 FAPSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEG 289
A +A+ APP A A + LP PP G A G T + G PE
Sbjct: 663 LAACHPAAWSRGPAPPLAFRGA---PGAPLPWPPATGPGSA---DGLCTIYETEG--PES 714
Query: 290 ATYAAPRGSSPKQSP 304
AT AP P SP
Sbjct: 715 AT-PAPGALDPGPSP 728
Score = 33.9 bits (76), Expect = 0.98
Identities = 39/148 (26%), Positives = 54/148 (36%), Gaps = 30/148 (20%)
Query: 178 LALGETTPSQLPARGTQ---------ARATGQS-FSQGTTSRAGHLAGPEPAPPP----- 222
L L + P PA T A GQ+ FS + LA P P PP
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 569
Query: 223 --PPPPREPFAPSLGSAFHLPDAPP--AAAAAALYYSSSTLPAPPRGGSPLAAPQG---- 274
PP P +P+L + P P + + L + + P PP SP + G
Sbjct: 570 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 629
Query: 275 -------GSPTKLQRGGSAPEGATYAAP 295
+P +L+ S PEG A+P
Sbjct: 630 GHSSSATSTPEELRGYDSGPEGGAAASP 657
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 62.4 bits (150), Expect = 3e-09
Identities = 98/370 (26%), Positives = 137/370 (37%), Gaps = 63/370 (17%)
Query: 204 QGTTSRAGHLAGPEPAPPPPPPPREPFAPSLG-----SAFHLPDAPPAAAAAALYYSSST 258
Q + A HL +PPP PP + PF+P SA APP+ AA L S
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 259 LPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATYAAPRGS---SPKQSPSRLAKSYSTSS 315
+PP SP A P +P L +AP +P S SP +P +
Sbjct: 711 PASPPM--SPSATPPPQAPPPL----AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
Query: 316 PINIVVS---SAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTY---ATLSPTKRLVHAS 369
P+ + S S +SP+ PP +++ P+ L S ++ A SP+ L
Sbjct: 765 PLQVPPSPPASLPMSPL-AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL---- 819
Query: 370 EQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHIDPIYEDRVY 429
AT Q P LAA S P LQ+P P + V
Sbjct: 820 ------PMSPLATPPPQAPPVLAAPLLQVPPSP-----PASPTLQAPRRPPTPGPDTSV- 867
Query: 430 QKPPMRSLSQSQGDPLPPAHTGTYRTS---TAPSSPGVDSVPLQRTGSQHGPQNAAAAT- 485
P +L+ + G P PP+ + + S A S S P + G GP+ AAA+
Sbjct: 868 -SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 926
Query: 486 --------FQRASYAAGPASNYA---DPYRQLQYCPSVE--------SPYSKSGP--ALP 524
A+++ GPA A P L + P+ + Y GP A P
Sbjct: 927 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986
Query: 525 PEGTLARSPS 534
G L PS
Sbjct: 987 APGALDPGPS 996
Score = 48.9 bits (115), Expect = 3e-05
Identities = 94/366 (25%), Positives = 137/366 (37%), Gaps = 79/366 (21%)
Query: 218 PAPPPPPPPREP---FAPSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQG 274
P+PP PP + P P + + L PP +L +S +L APP SPLA
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL--TSPSLQAPP---SPLALSSL 412
Query: 275 GSPTKLQRGGSAPEGATYA----APRGSSPK-QSPSRLAKSYSTSSPINIVVSSAGLSPI 329
+ T L GS AT++ +PR + SPSR A + S P+ +S P+
Sbjct: 413 QATTSL---GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469
Query: 330 RVTSPPTVQSTISSSPIHQLS--STIGTYATLSPTKRLVHASEQYSKHSQELYATATLQR 387
+ + P V S IH L S++ +++ +P L+ + +Q A +LQ
Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE----TQSSLAPPSLQT 525
Query: 388 P------------GSLA----AGSRASYSSQHGHLGP-----ELRALQSPEHHIDPIYED 426
P SLA + A ++ H P L+A SP P
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 427 RVY----QKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQ------------ 470
+ Q PP + QG P PP T + P + PLQ
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPP--LSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 471 --RTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGT 528
T S P NA A +A ++ P+ P V++P+S PA PP
Sbjct: 644 PLATPSPQAP-NALAVHLLQAPFSPPPS-------------PPVQAPFSP--PASPPVSP 687
Query: 529 LARSPS 534
A PS
Sbjct: 688 SATPPS 693
Score = 48.5 bits (114), Expect = 4e-05
Identities = 89/345 (25%), Positives = 124/345 (35%), Gaps = 48/345 (13%)
Query: 213 LAGPEPAPPP----PP---PPREPFAPSLGS-AFHLPDAPPAAAAAALYYSSSTLPAPP- 263
LA P P PP PP PP P +P L A P AP A A L S P+PP
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673
Query: 264 -----RGGSPLAAPQGGSPTKLQRGGSAPEGATYAAPRGS---SPKQSPSRLAKSYSTSS 315
SP +P P++ +AP +P S SP +P A +
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Query: 316 PINIVVSSAGLSPI--RVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYS 373
P+ + S P+ T PP V +++ P+ Q+ + +SP +
Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL-QVPPSPPASLPMSPLAK-------PP 785
Query: 374 KHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHIDPIYEDRVYQKPP 433
+ AT LQ S AS+ Q P SP P Q PP
Sbjct: 786 PQAPPALATPPLQALPS----PPASFPGQ-APFSPSASLPMSPLATPPP-------QAPP 833
Query: 434 MRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQ-NAAAATFQRASYA 492
+ + Q P PPA + T + P +PG D+ S GP+ A A +
Sbjct: 834 VLAAPLLQVPPSPPA-SPTLQAPRRPPTPGPDT-------SVSGPRLTLALAPGPPPPPS 885
Query: 493 AGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLARSPSIDS 537
P+S + P + +P G PEG A SP D+
Sbjct: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930
Score = 47.8 bits (112), Expect = 7e-05
Identities = 98/410 (23%), Positives = 145/410 (35%), Gaps = 79/410 (19%)
Query: 196 RATGQSFSQGTTSRAGHLAGPEP--APPPPPP---------------PREPFAPSLG--S 236
+A + ++ +RA L P P +P PPPP R+P A G
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 237 AFHLPDAPPAAAAAALYYSSSTLPA--PPRGGSPLAAP--QGGSPTKLQRGGSAPEGATY 292
+P++ P A +SS PA PP G AP + SP + G A G T
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA-SGTTR 125
Query: 293 AAPRGSSPKQ--SPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLS 350
P G + + +A+ +T +P +S+ R TS PT + S + + S
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR---RDTSGPTPGT--PSPAMARRS 180
Query: 351 STIGTYA--------------TLSPTKRLVHASEQYSKH-----SQELYATATLQRPGSL 391
GT T P K + ASE + + A LQRP S
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 392 AAGSRASYSSQHGHLGPELRAL-QSPEHHIDPIYEDRVYQKPPM---------RSLSQSQ 441
+ S A+ S GP R ++P H P + +PP +L
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 442 GDPL--------------PPAHTGTYRTSTAPSSPGVDS-VPLQRTGSQHGPQNAAAATF 486
PL PP + T +T P SP + + +PL P +
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Query: 487 QRASYAAGPASNYADPYR---QLQYCPSVESPYSKSGPAL-PPEGTLARS 532
+ P S P + LQ P ++ P+S + P+L P LA S
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 60.8 bits (146), Expect = 7e-09
Identities = 125/564 (22%), Positives = 199/564 (35%), Gaps = 81/564 (14%)
Query: 34 GLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETGSMS 93
G++TS+ DG + E + + +E ++ ++ +E +I S+ E +T +
Sbjct: 37 GVSTSSSDG-KAEKSRQTAKKARVEEASTPKVNKQGRSE-EISESESEETNAPKKTKTEQ 94
Query: 94 SMSSAEEQFQWQSQDGQKDIEDELTTGLELVDSCIRSLQES-----GILDPQDYSTG--- 145
+ + S DG + + D+ ++ +D RS S + + D S+G
Sbjct: 95 ELPRPQSPSDLDSLDG-RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQ 153
Query: 146 ------ERPSLLSQSALQLNS---KPEGSFQ-----YPASYHSNQ---TLALGETTPS-- 186
P L S +S +PE SF+ P YH+ T + + P
Sbjct: 154 GPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
Query: 187 ----QLPARGTQARATGQSFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHLPD 242
QL GT +G A + GP PPP S G++ P
Sbjct: 214 PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273
Query: 243 APPAAAAAALYYSSSTLPA----------PPRGGSPL----AAPQG----------GSPT 278
PP S+ PA PP PL A+P G SP
Sbjct: 274 KPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333
Query: 279 KLQRG-GSAPEGATYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTV 337
+ +G G P G SP P A S + + P+ SS+ S +S +
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPP--ASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 338 QSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAA---G 394
S+ S+SP S + +Y P + S Q K++Q + + G G
Sbjct: 392 SSS-SASPF-PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG 449
Query: 395 SRASYSSQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYR 454
+ S+ H P QS H + +Q+ + Q Q H G
Sbjct: 450 RLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHH-HQQQQQQQQQQQQQQQQQQQHHG--- 505
Query: 455 TSTAPSSPGVDSVPLQRTGSQHG-PQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVE 513
++ P PG PL+ S H P + + Y GPA + P+ Q+ Y
Sbjct: 506 -NSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA-HLPPPHSQVSY----- 558
Query: 514 SPYSKSGPALPPEGTLARSPSIDS 537
S++GP PP + + S S S
Sbjct: 559 ---SQAGPNGPPVSSSSNSSSSTS 579
Score = 42.4 bits (98), Expect = 0.003
Identities = 54/192 (28%), Positives = 71/192 (36%), Gaps = 16/192 (8%)
Query: 151 LSQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSFSQGTTSRA 210
+S S+ +S +GS YP S+ S G P T + AT S + A
Sbjct: 568 VSSSSNSSSSTSQGS--YPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT---LSTVIATVA 622
Query: 211 GHLAGPEPAPPPPPPPREPFAPSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLA 270
AG + A PP PPP APS G+ + PP + + P RG SP A
Sbjct: 623 SSPAGYKTASPPGPPPYGKRAPSPGA--YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPA 680
Query: 271 AP---QGGSPT----KLQRGGSAPEGATYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSS 323
P + GSPT L G P G P ++P P A
Sbjct: 681 GPGTFKPGSPTVGPGPLPPAG--PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE 738
Query: 324 AGLSPIRVTSPP 335
+ + P R SPP
Sbjct: 739 SPVPPARSPSPP 750
Score = 33.9 bits (76), Expect = 0.98
Identities = 44/160 (27%), Positives = 59/160 (36%), Gaps = 32/160 (20%)
Query: 220 PPPP---PPPRE--------PFA--PSLGSAFHLPDAPPAAAA--AALYYSSSTLPAPP- 263
PPPP P P E P+A PSLGS P P + + YS + PP
Sbjct: 509 PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPV 568
Query: 264 --RGGSPLAAPQGGSPTKLQRGGSAPEGATYAAPRGSSPKQSPSRLAKSYSTSSPINIVV 321
S + QG P P+GA Y P P+ S + S+ I V
Sbjct: 569 SSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFP------PVPTVTTSSATLSTVIATVA 622
Query: 322 SSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSP 361
SS + + SPP P + + + G Y T +P
Sbjct: 623 SSP--AGYKTASPP------GPPPYGKRAPSPGAYKTATP 654
Score = 33.9 bits (76), Expect = 0.98
Identities = 78/327 (23%), Positives = 105/327 (32%), Gaps = 37/327 (11%)
Query: 185 PSQLPARGTQARATGQSFSQGTTSRAGHLAGPE-PAPP---PPPPPREPFAPSLGSAF-- 238
PS P A S +Q A PE P PP P PPP+ PS S
Sbjct: 706 PSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSAR 765
Query: 239 ---HLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKL-----QRGGSAPEGA 290
HL + A + LY+ P GS LA + K+ QR E
Sbjct: 766 FNKHLDRGFNSCARSDLYF-------VPLEGSKLAKKRADLVEKVRREAEQRAREEKERE 818
Query: 291 TYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLS 350
++ L +S + V L P+ P S +++ P + L
Sbjct: 819 REREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPY-LG 877
Query: 351 STIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPEL 410
TLS R S H Y PG L A YSS E
Sbjct: 878 PDTPALRTLSEYARPHVMSPGNRNH--PFYVPLGAVDPGLLGYNVPALYSSDPAARERER 935
Query: 411 RALQSP-EHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPL 469
A + + P +E + + P+ + DP P H G + P PG+ P
Sbjct: 936 EARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPF-PRHGG---LALQPGPPGLHPFPF 991
Query: 470 QRTGSQHGPQNAAAATFQRASYAAGPA 496
GP +R + AAGPA
Sbjct: 992 H---PSLGPLER-----ERLALAAGPA 1010
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 60.8 bits (146), Expect = 7e-09
Identities = 125/564 (22%), Positives = 199/564 (35%), Gaps = 81/564 (14%)
Query: 34 GLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETGSMS 93
G++TS+ DG + E + + +E ++ ++ +E +I S+ E +T +
Sbjct: 37 GVSTSSSDG-KAEKSRQTAKKARVEEASTPKVNKQGRSE-EISESESEETNAPKKTKTEQ 94
Query: 94 SMSSAEEQFQWQSQDGQKDIEDELTTGLELVDSCIRSLQES-----GILDPQDYSTG--- 145
+ + S DG + + D+ ++ +D RS S + + D S+G
Sbjct: 95 ELPRPQSPSDLDSLDG-RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQ 153
Query: 146 ------ERPSLLSQSALQLNS---KPEGSFQ-----YPASYHSNQ---TLALGETTPS-- 186
P L S +S +PE SF+ P YH+ T + + P
Sbjct: 154 GPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
Query: 187 ----QLPARGTQARATGQSFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHLPD 242
QL GT +G A + GP PPP S G++ P
Sbjct: 214 PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273
Query: 243 APPAAAAAALYYSSSTLPA----------PPRGGSPL----AAPQG----------GSPT 278
PP S+ PA PP PL A+P G SP
Sbjct: 274 KPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333
Query: 279 KLQRG-GSAPEGATYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTV 337
+ +G G P G SP P A S + + P+ SS+ S +S +
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPP--ASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 338 QSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAA---G 394
S+ S+SP S + +Y P + S Q K++Q + + G G
Sbjct: 392 SSS-SASPF-PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG 449
Query: 395 SRASYSSQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYR 454
+ S+ H P QS H + +Q+ + Q Q H G
Sbjct: 450 RLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHH-HQQQQQQQQQQQQQQQQQQQHHG--- 505
Query: 455 TSTAPSSPGVDSVPLQRTGSQHG-PQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVE 513
++ P PG PL+ S H P + + Y GPA + P+ Q+ Y
Sbjct: 506 -NSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA-HLPPPHSQVSY----- 558
Query: 514 SPYSKSGPALPPEGTLARSPSIDS 537
S++GP PP + + S S S
Sbjct: 559 ---SQAGPNGPPVSSSSNSSSSTS 579
Score = 42.4 bits (98), Expect = 0.003
Identities = 54/192 (28%), Positives = 71/192 (36%), Gaps = 16/192 (8%)
Query: 151 LSQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSFSQGTTSRA 210
+S S+ +S +GS YP S+ S G P T + AT S + A
Sbjct: 568 VSSSSNSSSSTSQGS--YPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT---LSTVIATVA 622
Query: 211 GHLAGPEPAPPPPPPPREPFAPSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLA 270
AG + A PP PPP APS G+ + PP + + P RG SP A
Sbjct: 623 SSPAGYKTASPPGPPPYGKRAPSPGA--YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPA 680
Query: 271 AP---QGGSPT----KLQRGGSAPEGATYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSS 323
P + GSPT L G P G P ++P P A
Sbjct: 681 GPGTFKPGSPTVGPGPLPPAG--PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE 738
Query: 324 AGLSPIRVTSPP 335
+ + P R SPP
Sbjct: 739 SPVPPARSPSPP 750
Score = 33.9 bits (76), Expect = 0.98
Identities = 44/160 (27%), Positives = 59/160 (36%), Gaps = 32/160 (20%)
Query: 220 PPPP---PPPRE--------PFA--PSLGSAFHLPDAPPAAAA--AALYYSSSTLPAPP- 263
PPPP P P E P+A PSLGS P P + + YS + PP
Sbjct: 509 PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPV 568
Query: 264 --RGGSPLAAPQGGSPTKLQRGGSAPEGATYAAPRGSSPKQSPSRLAKSYSTSSPINIVV 321
S + QG P P+GA Y P P+ S + S+ I V
Sbjct: 569 SSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFP------PVPTVTTSSATLSTVIATVA 622
Query: 322 SSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSP 361
SS + + SPP P + + + G Y T +P
Sbjct: 623 SSP--AGYKTASPP------GPPPYGKRAPSPGAYKTATP 654
Score = 33.9 bits (76), Expect = 0.98
Identities = 78/327 (23%), Positives = 105/327 (32%), Gaps = 37/327 (11%)
Query: 185 PSQLPARGTQARATGQSFSQGTTSRAGHLAGPE-PAPP---PPPPPREPFAPSLGSAF-- 238
PS P A S +Q A PE P PP P PPP+ PS S
Sbjct: 706 PSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSAR 765
Query: 239 ---HLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKL-----QRGGSAPEGA 290
HL + A + LY+ P GS LA + K+ QR E
Sbjct: 766 FNKHLDRGFNSCARSDLYF-------VPLEGSKLAKKRADLVEKVRREAEQRAREEKERE 818
Query: 291 TYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLS 350
++ L +S + V L P+ P S +++ P + L
Sbjct: 819 REREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPY-LG 877
Query: 351 STIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPEL 410
TLS R S H Y PG L A YSS E
Sbjct: 878 PDTPALRTLSEYARPHVMSPGNRNH--PFYVPLGAVDPGLLGYNVPALYSSDPAARERER 935
Query: 411 RALQSP-EHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPL 469
A + + P +E + + P+ + DP P H G + P PG+ P
Sbjct: 936 EARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPF-PRHGG---LALQPGPPGLHPFPF 991
Query: 470 QRTGSQHGPQNAAAATFQRASYAAGPA 496
GP +R + AAGPA
Sbjct: 992 H---PSLGPLER-----ERLALAAGPA 1010
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,107,285
Number of Sequences: 37866
Number of extensions: 2890962
Number of successful extensions: 27661
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 275
Number of HSP's successfully gapped in prelim test: 1306
Number of HSP's that attempted gapping in prelim test: 16402
Number of HSP's gapped (non-prelim): 7394
length of query: 1225
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1111
effective length of database: 13,930,794
effective search space: 15477112134
effective search space used: 15477112134
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.