Guide to the Human Genome
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Search of human proteins with 156104883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156104883 guanine nucleotide binding protein (G protein),
alpha 15 (Gq class) [Homo sapiens]
         (374 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156104883 guanine nucleotide binding protein (G protein), alp...   758   0.0  
gi|40254462 guanine nucleotide binding protein (G protein), q po...   400   e-111
gi|115511049 guanine nucleotide binding protein (G protein), alp...   397   e-111
gi|4758444 G alpha 14 [Homo sapiens]                                  384   e-106
gi|24111250 guanine nucleotide binding protein (G protein), alph...   286   2e-77
gi|33946324 guanine nucleotide binding protein (G protein), alph...   282   3e-76
gi|156139155 guanine nucleotide binding protein, alpha transduci...   281   7e-76
gi|4504041 guanine nucleotide binding protein (G protein), alpha...   280   1e-75
gi|162461738 guanine nucleotide binding protein, alpha activatin...   280   1e-75
gi|5729850 guanine nucleotide binding protein (G protein), alpha...   280   2e-75
gi|22027522 rod-type transducin alpha subunit [Homo sapiens]          277   1e-74
gi|22027520 rod-type transducin alpha subunit [Homo sapiens]          277   1e-74
gi|20330805 guanine nucleotide binding protein, alpha transducin...   276   2e-74
gi|42476111 guanine nucleotide binding protein (G protein) alpha...   270   1e-72
gi|10567816 guanine nucleotide binding protein, alpha activating...   270   1e-72
gi|4504051 guanine nucleotide binding protein, alpha z polypepti...   268   6e-72
gi|33695153 guanine nucleotide binding protein (G protein), alph...   252   3e-67
gi|4504043 guanine nucleotide binding protein (G protein), alpha...   247   1e-65
gi|215272301 guanine nucleotide binding protein (G protein), alp...   247   1e-65
gi|117938765 GNAS complex locus isoform g [Homo sapiens]              243   2e-64
gi|18426900 GNAS complex locus GNASS [Homo sapiens]                   242   5e-64
gi|4504047 GNAS complex locus GNASL [Homo sapiens]                    236   3e-62
gi|117938762 GNAS complex locus isoform f [Homo sapiens]              235   4e-62
gi|117938759 GNAS complex locus XLas [Homo sapiens]                   228   7e-60
gi|4757774 ADP-ribosylation factor-like 3 [Homo sapiens]               45   8e-05
gi|13376574 ADP-ribosylation factor-like 14 [Homo sapiens]             43   4e-04
gi|4502209 ADP-ribosylation factor 5 [Homo sapiens]                    43   5e-04
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet...    41   0.002
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    40   0.003
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph...    40   0.003

>gi|156104883 guanine nucleotide binding protein (G protein), alpha
           15 (Gq class) [Homo sapiens]
          Length = 374

 Score =  758 bits (1958), Expect = 0.0
 Identities = 374/374 (100%), Positives = 374/374 (100%)

Query: 1   MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK 60
           MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
Sbjct: 1   MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK 60

Query: 61  QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD 120
           QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
Sbjct: 61  QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD 120

Query: 121 PYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ 180
           PYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
Sbjct: 121 PYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ 180

Query: 181 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ 240
           DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
Sbjct: 181 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ 240

Query: 241 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG 300
           CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
Sbjct: 241 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG 300

Query: 301 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 360
           PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
Sbjct: 301 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 360

Query: 361 DSVLARYLDEINLL 374
           DSVLARYLDEINLL
Sbjct: 361 DSVLARYLDEINLL 374


>gi|40254462 guanine nucleotide binding protein (G protein), q
           polypeptide [Homo sapiens]
          Length = 359

 Score =  400 bits (1028), Expect = e-111
 Identities = 201/362 (55%), Positives = 262/362 (72%), Gaps = 12/362 (3%)

Query: 13  CLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSE 72
           CL+E+ K A R++ EI R L   K+  R ELKLLLLG GESGKSTFIKQMRIIHG+GYS+
Sbjct: 10  CLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSD 69

Query: 73  EERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYA 132
           E+++GF  LVYQNIF +M+AMI AM+ L+IP+    +K HA LV   D  KV+ FE  Y 
Sbjct: 70  EDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYV 129

Query: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192
            A++ LW D GI+  Y+RRRE+ L DS  YYL+ L+R+ +  Y+PT QDVLR R+PTTGI
Sbjct: 130 DAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGI 189

Query: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252
            EY F +Q    R+VDVGGQ+SER+KWIHCFENV ++++L +LSEYDQ L E++ ENRM+
Sbjct: 190 IEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRME 249

Query: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFI 312
           ES ALF TI+  PWF+++SVILFLNK D+LEEKI  SHL  YFP + GP++DA+AA+ FI
Sbjct: 250 ESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFI 309

Query: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372
           L M+  +       P+  K       ++SH+TCATDT+NIR VF  V+D++L   L E N
Sbjct: 310 LKMFVDL------NPDSDK------IIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYN 357

Query: 373 LL 374
           L+
Sbjct: 358 LV 359


>gi|115511049 guanine nucleotide binding protein (G protein), alpha
           11 (Gq class) [Homo sapiens]
          Length = 359

 Score =  397 bits (1021), Expect = e-111
 Identities = 201/362 (55%), Positives = 266/362 (73%), Gaps = 12/362 (3%)

Query: 13  CLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSE 72
           CL+++ K + R++ EI + L   K+  R ELKLLLLG GESGKSTFIKQMRIIHGAGYSE
Sbjct: 10  CLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSE 69

Query: 73  EERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYA 132
           E+++GF  LVYQNIF +M+AMI AME L+I +   ++K +A L+   D  KVTTFE +Y 
Sbjct: 70  EDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYV 129

Query: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192
           +A++ LW D GI+  Y+RRRE+ L DSA YYL+ ++RI   GY+PT QDVLR R+PTTGI
Sbjct: 130 SAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGI 189

Query: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252
            EY F ++    R+VDVGGQ+SER+KWIHCFENV ++++L +LSEYDQ L E++ ENRM+
Sbjct: 190 IEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRME 249

Query: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFI 312
           ES ALF TI+  PWF+++SVILFLNK D+LE+KI  SHL  YFP F GP++DA+AA+ FI
Sbjct: 250 ESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFI 309

Query: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372
           L M+  +       P+  K       ++SH+TCATDT+NIR VF  V+D++L   L E N
Sbjct: 310 LKMFVDL------NPDSDK------IIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYN 357

Query: 373 LL 374
           L+
Sbjct: 358 LV 359


>gi|4758444 G alpha 14 [Homo sapiens]
          Length = 355

 Score =  384 bits (985), Expect = e-106
 Identities = 196/366 (53%), Positives = 257/366 (70%), Gaps = 14/366 (3%)

Query: 9   CCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGA 68
           CC  CL+ +EK + R+  EI R L   KK  R ELKLLLLG GESGKSTFIKQMRIIHG+
Sbjct: 4   CC--CLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGS 61

Query: 69  GYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFE 128
           GYS+E+RKGF  LVYQNIF +M+AMI AM+ L+I +   ++K +A ++   +  KV+   
Sbjct: 62  GYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLS 121

Query: 129 KRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMP 188
           +    A++ LW+D GI+  Y+RRRE+ L DSA YYL+ ++RI    +VPT QDVLR R+P
Sbjct: 122 REQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVP 181

Query: 189 TTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQE 248
           TTGI EY F ++    R+VDVGGQ+SER+KWIHCFE+V ++I+L +LSEYDQ L E + E
Sbjct: 182 TTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNE 241

Query: 249 NRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAA 308
           NRM+ES ALF TI+  PWF ++SVILFLNK D+LEEKI  SHL +YFP + GPKQD  AA
Sbjct: 242 NRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAA 301

Query: 309 KRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYL 368
           + FIL +Y              +   + + ++SH+TCATDT NIR VF  V+D++L   L
Sbjct: 302 RDFILKLYQ------------DQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNL 349

Query: 369 DEINLL 374
            E NL+
Sbjct: 350 REFNLV 355


>gi|24111250 guanine nucleotide binding protein (G protein), alpha
           13 [Homo sapiens]
          Length = 377

 Score =  286 bits (733), Expect = 2e-77
 Identities = 149/381 (39%), Positives = 232/381 (60%), Gaps = 20/381 (5%)

Query: 2   ARSLTWRCCPWCL-TEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK 60
           +RS+   C P CL T  E    R  +EI++ L  +K   +  +K+LLLG GESGKSTF+K
Sbjct: 7   SRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLK 66

Query: 61  QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD 120
           QMRIIHG  + +  R+ FRP +Y N+   MR +++A E+L IP+    ++ H   +MS D
Sbjct: 67  QMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFD 126

Query: 121 PYKV--------TTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITE 172
                       T    +Y  A++ LW D+GI+  Y+RRREF L +S  Y+L +L+++ E
Sbjct: 127 TRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGE 186

Query: 173 EGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYL 232
             Y+P+ QD+L +R PT GI+EY F ++    ++VDVGGQ+SERK+W  CF++V ++++L
Sbjct: 187 PDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFL 246

Query: 233 ASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLA 292
            S SE+DQ L E+   NR+ ESL +F TI+    F + S+ILFLNKTD+LEEK+    + 
Sbjct: 247 VSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIK 306

Query: 293 TYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNI 352
            YF  F+G        ++F+++ +              ++  + + L+ H+T A +T+NI
Sbjct: 307 DYFLEFEGDPHCLRDVQKFLVECF-----------RNKRRDQQQKPLYHHFTTAINTENI 355

Query: 353 RKVFKDVRDSVLARYLDEINL 373
           R VF+DV+D++L   L ++ L
Sbjct: 356 RLVFRDVKDTILHDNLKQLML 376


>gi|33946324 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 1 [Homo sapiens]
          Length = 354

 Score =  282 bits (722), Expect = 3e-76
 Identities = 158/363 (43%), Positives = 222/363 (61%), Gaps = 17/363 (4%)

Query: 14  LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEE 73
           L+ ++KAA    + I+R L E  ++   E+KLLLLG GESGKST +KQM+IIH AGYSEE
Sbjct: 5   LSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEE 64

Query: 74  ERKGFRPLVYQNIFVSMRAMIEAMERLQIPF---SRPESKHHASLVMSQDPYKVTTFEKR 130
           E K ++ +VY N   S+ A+I AM RL+I F   +R +      ++         T E  
Sbjct: 65  ECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAE-- 122

Query: 131 YAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTT 190
            A  ++ LW+D+G++A + R RE+ L DSA YYL+ L+RI +  Y+PT QDVLR+R+ TT
Sbjct: 123 LAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTT 182

Query: 191 GINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENR 250
           GI E  F+ +  + ++ DVGGQ+SERKKWIHCFE V A+I+  +LS+YD  L E+ + NR
Sbjct: 183 GIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNR 242

Query: 251 MKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKR 310
           M ES+ LF +I    WF  TS+ILFLNK D+ EEKI  S L   +P + G     EAA  
Sbjct: 243 MHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA-- 300

Query: 311 FILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDE 370
                    Y  C    E   K   ++ +++H+TCATDT+N++ VF  V D ++   L +
Sbjct: 301 --------AYIQCQF--EDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 350

Query: 371 INL 373
             L
Sbjct: 351 CGL 353


>gi|156139155 guanine nucleotide binding protein, alpha transducing
           3 [Homo sapiens]
          Length = 354

 Score =  281 bits (719), Expect = 7e-76
 Identities = 154/364 (42%), Positives = 217/364 (59%), Gaps = 19/364 (5%)

Query: 14  LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEE 73
           ++ + K +A+  +E+ + L E  ++D   +KLLLLG GESGKST +KQM+IIH  GYSE+
Sbjct: 5   ISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQ 64

Query: 74  ERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPES-KHHASLVMSQDPYKVTTFEKRYA 132
           E   F+ ++Y N   S+ A+++AM  L I +  P S +    L    +  +      + A
Sbjct: 65  ECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLEDGGMTPQLA 124

Query: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192
             ++ LWRD GI+A +ER  E+ L DSA YYL+ L+RIT  GYVP  QDVL SR+ TTGI
Sbjct: 125 EVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGI 184

Query: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252
            E  FS +  + R+ DVGGQ+SERKKWIHCFE V  +I+ A+LS YD  L E+ + NRM 
Sbjct: 185 IETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMH 244

Query: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAA---K 309
           ESL LF +I    +F +TS++LFLNK DI +EK+   HL+  FP + GP    +A    K
Sbjct: 245 ESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTGPNTFEDAGNYIK 304

Query: 310 RFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLD 369
              LD+  +                  + ++SH TCATDTQN++ VF  V D ++   L 
Sbjct: 305 NQFLDLNLK---------------KEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349

Query: 370 EINL 373
           +  L
Sbjct: 350 DCGL 353


>gi|4504041 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 2 [Homo sapiens]
          Length = 355

 Score =  280 bits (716), Expect = 1e-75
 Identities = 155/362 (42%), Positives = 220/362 (60%), Gaps = 14/362 (3%)

Query: 14  LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEE 73
           ++ ++KAAA   + I++ L E  ++   E+KLLLLG GESGKST +KQM+IIH  GYSEE
Sbjct: 5   VSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEE 64

Query: 74  ERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHAS--LVMSQDPYKVTTFEKRY 131
           E + +R +VY N   S+ A+++AM  LQI F+ P     A     +S    +        
Sbjct: 65  ECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDL 124

Query: 132 AAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTG 191
           +  ++ LW D G++A + R RE+ L DSA YYL+ LERI +  Y+PT QDVLR+R+ TTG
Sbjct: 125 SGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTG 184

Query: 192 INEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRM 251
           I E  F+ +  + ++ DVGGQ+SERKKWIHCFE V A+I+  +LS YD  L E+ + NRM
Sbjct: 185 IVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRM 244

Query: 252 KESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRF 311
            ES+ LF +I    WF  TS+ILFLNK D+ EEKI  S L   FP + G  +  EAA  +
Sbjct: 245 HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAAS-Y 303

Query: 312 ILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEI 371
           I   +           E   K   ++ +++H+TCATDT+N++ VF  V D ++   L + 
Sbjct: 304 IQSKF-----------EDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDC 352

Query: 372 NL 373
            L
Sbjct: 353 GL 354


>gi|162461738 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform b [Homo sapiens]
          Length = 354

 Score =  280 bits (716), Expect = 1e-75
 Identities = 159/357 (44%), Positives = 211/357 (59%), Gaps = 15/357 (4%)

Query: 14  LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEE 73
           L+ +E+AA    + I + L E       ++KLLLLG GESGKST +KQM+IIH  G+S E
Sbjct: 5   LSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGE 64

Query: 74  ERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTT--FEKRY 131
           + K ++P+VY N   S+ A++ AM+ L I +   E K  A +V         T  F    
Sbjct: 65  DVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAEL 124

Query: 132 AAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTG 191
            +AM  LW D+GI+  + R RE+ L DSA YYL  L+RI    Y PT QD+LR+R+ TTG
Sbjct: 125 LSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTG 184

Query: 192 INEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRM 251
           I E  F+ +  + R+ DVGGQ+SERKKWIHCFE+V A+I+  +LS YDQ L E+   NRM
Sbjct: 185 IVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRM 244

Query: 252 KESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRF 311
            ESL LF +I    WF  TS+ILFLNK DI EEKI  S L   FP + GP    EA   +
Sbjct: 245 HESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSAFTEAV-AY 303

Query: 312 ILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYL 368
           I   Y             SK  +  + +++H TCATDT NI+ VF  V D ++A+ L
Sbjct: 304 IQAQYE------------SKNKSAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNL 348


>gi|5729850 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 3 [Homo sapiens]
          Length = 354

 Score =  280 bits (715), Expect = 2e-75
 Identities = 158/363 (43%), Positives = 221/363 (60%), Gaps = 17/363 (4%)

Query: 14  LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEE 73
           L+ ++KAA    + I+R L E  ++   E+KLLLLG GESGKST +KQM+IIH  GYSE+
Sbjct: 5   LSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSED 64

Query: 74  ERKGFRPLVYQNIFVSMRAMIEAMERLQIPF---SRPESKHHASLVMSQDPYKVTTFEKR 130
           E K ++ +VY N   S+ A+I AM RL+I F   +R +      ++       V T E  
Sbjct: 65  ECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMTPE-- 122

Query: 131 YAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTT 190
            A  ++ LWRD G++A + R RE+ L DSA YYL+ L+RI++  Y+PT QDVLR+R+ TT
Sbjct: 123 LAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTT 182

Query: 191 GINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENR 250
           GI E  F+ +    ++ DVGGQ+SERKKWIHCFE V A+I+  +LS+YD  L E+ + NR
Sbjct: 183 GIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNR 242

Query: 251 MKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKR 310
           M ES+ LF +I    WF  TS+ILFLNK D+ EEKI  S L   +P + G     EAA  
Sbjct: 243 MHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA-- 300

Query: 311 FILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDE 370
                    Y  C    E   +   ++ +++H+TCATDT+N++ VF  V D ++   L E
Sbjct: 301 --------AYIQCQF--EDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 350

Query: 371 INL 373
             L
Sbjct: 351 CGL 353


>gi|22027522 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  277 bits (708), Expect = 1e-74
 Identities = 156/355 (43%), Positives = 213/355 (60%), Gaps = 13/355 (3%)

Query: 20  AAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFR 79
           A  +  +E+ + L E  ++D   +KLLLLG GESGKST +KQM+IIH  GYS EE   F 
Sbjct: 7   AEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFI 66

Query: 80  PLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQ-DPYKVTTFEKRYAAAMQWL 138
            ++Y N   S+ A++ AM  L I +     +  A  +M   D  +  T  K  +  +Q L
Sbjct: 67  AIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRL 126

Query: 139 WRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFS 198
           W+D+GI+A +ER  E+ L DSA YYLS LER+   GYVPT QDVLRSR+ TTGI E  FS
Sbjct: 127 WKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFS 186

Query: 199 VQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALF 258
            +  N R+ DVGGQ+SERKKWIHCFE V  +I++A+LS YD  L E+++ NRM ESL LF
Sbjct: 187 FKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLF 246

Query: 259 GTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTR 318
            +I    +F +TS++LFLNK D+  EKI  +HL+  FP + GP    E A  +I   +  
Sbjct: 247 NSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDGP-NTYEDAGNYIKVQFLE 305

Query: 319 MYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINL 373
           +                 + ++SH TCATDTQN++ VF  V D ++   L +  L
Sbjct: 306 L-----------NMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGL 349


>gi|22027520 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  277 bits (708), Expect = 1e-74
 Identities = 156/355 (43%), Positives = 213/355 (60%), Gaps = 13/355 (3%)

Query: 20  AAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFR 79
           A  +  +E+ + L E  ++D   +KLLLLG GESGKST +KQM+IIH  GYS EE   F 
Sbjct: 7   AEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFI 66

Query: 80  PLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQ-DPYKVTTFEKRYAAAMQWL 138
            ++Y N   S+ A++ AM  L I +     +  A  +M   D  +  T  K  +  +Q L
Sbjct: 67  AIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRL 126

Query: 139 WRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFS 198
           W+D+GI+A +ER  E+ L DSA YYLS LER+   GYVPT QDVLRSR+ TTGI E  FS
Sbjct: 127 WKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFS 186

Query: 199 VQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALF 258
            +  N R+ DVGGQ+SERKKWIHCFE V  +I++A+LS YD  L E+++ NRM ESL LF
Sbjct: 187 FKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLF 246

Query: 259 GTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTR 318
            +I    +F +TS++LFLNK D+  EKI  +HL+  FP + GP    E A  +I   +  
Sbjct: 247 NSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDGP-NTYEDAGNYIKVQFLE 305

Query: 319 MYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINL 373
           +                 + ++SH TCATDTQN++ VF  V D ++   L +  L
Sbjct: 306 L-----------NMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGL 349


>gi|20330805 guanine nucleotide binding protein, alpha transducing
           activity polypeptide 2 [Homo sapiens]
          Length = 354

 Score =  276 bits (707), Expect = 2e-74
 Identities = 154/361 (42%), Positives = 215/361 (59%), Gaps = 19/361 (5%)

Query: 17  DEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERK 76
           ++K  A+  +E+ + L E   ++   +KLLLLG GESGKST +KQM+IIH  GYS EE  
Sbjct: 8   EDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECL 67

Query: 77  GFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMS-QDPYKVTTFEKRYAAAM 135
            F+ ++Y N+  S+ A+I AM  L I ++ P        + +  D  +  T        +
Sbjct: 68  EFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQLNNLADSIEEGTMPPELVEVI 127

Query: 136 QWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEY 195
           + LW+D G++A +ER  E+ L DSA YYL+ LERIT+  Y+P+ QDVLRSR+ TTGI E 
Sbjct: 128 RRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVKTTGIIET 187

Query: 196 CFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESL 255
            FSV+  N R+ DVGGQ+SERKKWIHCFE V  +I+ A+LS YD  L E+++ NRM ESL
Sbjct: 188 KFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESL 247

Query: 256 ALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAA---KRFI 312
            LF +I    +F +TS++LFLNK D+ EEKI   HL+  FP + G     +A    K   
Sbjct: 248 HLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYDDAGNYIKSQF 307

Query: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372
           LD+  R                  + ++SH TCATDTQN++ VF  V D ++   L +  
Sbjct: 308 LDLNMRKDV---------------KEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCG 352

Query: 373 L 373
           L
Sbjct: 353 L 353


>gi|42476111 guanine nucleotide binding protein (G protein) alpha 12
           [Homo sapiens]
          Length = 381

 Score =  270 bits (691), Expect = 1e-72
 Identities = 141/361 (39%), Positives = 223/361 (61%), Gaps = 18/361 (4%)

Query: 18  EKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKG 77
           E+ A R  ++I+ +L  +++  R  +K+LLLG GESGKSTF+KQMRIIHG  + ++    
Sbjct: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92

Query: 78  FRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD-----PYKVTTFEKRYA 132
           FR  ++ NI    R +++A ++L IP+   E++ H   +M+ +     P +  TF+  Y 
Sbjct: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQL-YV 151

Query: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192
            A+  LWRD+GIR  + RR EF L +S  Y+L +L+RI +  Y P+ QD+L +R  T GI
Sbjct: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211

Query: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252
            E+ F ++K   ++VDVGGQ+S+R+KW  CF+ + +++++ S SEYDQ L E+ + NR+ 
Sbjct: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271

Query: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFI 312
           ES+ +F TI+    F + S+ILFLNK D+L EK+ T  +  +FP F+G     E  +R++
Sbjct: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331

Query: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372
           +  + R            K+  RS+ LF H+T A DT+N+R VF  V+D++L   L +I 
Sbjct: 332 VQCFDR------------KRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIM 379

Query: 373 L 373
           L
Sbjct: 380 L 380


>gi|10567816 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform a [Homo sapiens]
          Length = 354

 Score =  270 bits (691), Expect = 1e-72
 Identities = 154/357 (43%), Positives = 208/357 (58%), Gaps = 15/357 (4%)

Query: 14  LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEE 73
           L+ +E+AA    + I + L E       ++KLLLLG GESGKST +KQM+IIH  G+S E
Sbjct: 5   LSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGE 64

Query: 74  ERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTT--FEKRY 131
           + K ++P+VY N   S+ A++ AM+ L I +   E K  A +V         T  F    
Sbjct: 65  DVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAEL 124

Query: 132 AAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTG 191
            +AM  LW D+GI+  + R RE+ L DSA YYL  L+RI    Y PT QD+LR+R+ TTG
Sbjct: 125 LSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTG 184

Query: 192 INEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRM 251
           I E  F+ +  + R+ DVGGQ+SERKKWIHCFE+V A+I+  +LS YDQ L E+   NRM
Sbjct: 185 IVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRM 244

Query: 252 KESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRF 311
            ESL LF +I    +F  TS+ILFLNK D+  EKI  S L   FP + GP    +AA   
Sbjct: 245 HESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAA--- 301

Query: 312 ILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYL 368
                       +     SK  + ++ ++ H TCATDT NI+ VF  V D ++A  L
Sbjct: 302 ----------AYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNL 348


>gi|4504051 guanine nucleotide binding protein, alpha z polypeptide
           [Homo sapiens]
          Length = 355

 Score =  268 bits (685), Expect = 6e-72
 Identities = 152/361 (42%), Positives = 212/361 (58%), Gaps = 14/361 (3%)

Query: 15  TEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEE 74
           + +EK AAR  + I+R L  + ++ R E+KLLLLG   SGKST +KQM+IIH  G++ E 
Sbjct: 6   SSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEA 65

Query: 75  RKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFE--KRYA 132
            K ++PL+  N   S+  +I A+  L+I F  P+  + A  + +      +  E      
Sbjct: 66  CKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELL 125

Query: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192
             M+ LW D G +A + R  E+HL D+A YYL+ LERI    Y+PT +D+LRSR  TTGI
Sbjct: 126 GVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGI 185

Query: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252
            E  F+ ++   ++VDVGGQ+SERKKWIHCFE V A+I+   LS YD  L E+NQ +RM 
Sbjct: 186 VENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMA 245

Query: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFI 312
           ESL LF +I    WF +TS+ILFLNK D+L EKI    L   FP ++G     EAA  +I
Sbjct: 246 ESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAV-YI 304

Query: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372
              +           E   +   ++ ++SH+TCATDT NI+ VF  V D ++   L  I 
Sbjct: 305 QRQF-----------EDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIG 353

Query: 373 L 373
           L
Sbjct: 354 L 354


>gi|33695153 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           1 [Homo sapiens]
          Length = 458

 Score =  252 bits (644), Expect = 3e-67
 Identities = 140/375 (37%), Positives = 215/375 (57%), Gaps = 25/375 (6%)

Query: 16  EDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEER 75
           E  K A +V + I+R+L +QK+  +   +LLLLG GESGKST +KQMRI+H  G++ EE+
Sbjct: 93  EAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEK 152

Query: 76  KGFRPLVYQNIFVSMRAMIEAMERL--QIPFSRPESKHHASLVMSQDPYKVTTFEKRYAA 133
           K     + +N+  ++  ++ AM  +   +P + PE++  +  + S  P     + + +  
Sbjct: 153 KQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFD 212

Query: 134 AMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGIN 193
            ++ LW D G++A +ER  E+ L+D A Y+L  ++ ++   Y PT QD+LR R+ T+GI 
Sbjct: 213 HVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIF 272

Query: 194 EYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKE 253
           E  F V K N  + DVGGQ+ ER+KWI CF +V A+IY+A+ S Y+  + E+N  NR++E
Sbjct: 273 ETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRE 332

Query: 254 SLALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFPSF------------Q 299
           SL LF +I    W ++ S+ILFLNK D+L EK+    S +  YFP +             
Sbjct: 333 SLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDA 392

Query: 300 GPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDV 359
           G       AK FI D++ R+ T   DG             + H+TCA DT+NIR+VF D 
Sbjct: 393 GEDPKVTRAKFFIRDLFLRISTATGDG---------KHYCYPHFTCAVDTENIRRVFNDC 443

Query: 360 RDSVLARYLDEINLL 374
           RD +   +L +  LL
Sbjct: 444 RDIIQRMHLKQYELL 458


>gi|4504043 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  247 bits (631), Expect = 1e-65
 Identities = 136/374 (36%), Positives = 212/374 (56%), Gaps = 25/374 (6%)

Query: 17  DEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERK 76
           DEK     +++I + L +++   +   +LLLLG GESGKST +KQMRI+H  G++ EE+K
Sbjct: 17  DEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKK 76

Query: 77  GFRPLVYQNIFVSMRAMIEAMERL--QIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAA 134
                + +N+  ++  ++ AM  +   +P + PE++  +  + S  P     + + +   
Sbjct: 77  QKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDH 136

Query: 135 MQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINE 194
           ++ LW D G++A +ER  E+ L+D A Y+L  ++ ++   Y PT QD+LR R+ T+GI E
Sbjct: 137 VKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFE 196

Query: 195 YCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKES 254
             F V K N  + DVGGQ+ ER+KWI CF +V A+IY+A+ S Y+  + E+N  NR++ES
Sbjct: 197 TRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRES 256

Query: 255 LALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFPSF------------QG 300
           L LF +I    W ++ S+ILFLNK D+L EK+    S +  YFP +             G
Sbjct: 257 LDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAG 316

Query: 301 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 360
                  AK FI D++ R+ T   DG             + H+TCA DT+NIR+VF D R
Sbjct: 317 EDPKVTRAKFFIRDLFLRISTATGDG---------KHYCYPHFTCAVDTENIRRVFNDCR 367

Query: 361 DSVLARYLDEINLL 374
           D +   +L +  LL
Sbjct: 368 DIIQRMHLKQYELL 381


>gi|215272301 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  247 bits (631), Expect = 1e-65
 Identities = 136/374 (36%), Positives = 212/374 (56%), Gaps = 25/374 (6%)

Query: 17  DEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERK 76
           DEK     +++I + L +++   +   +LLLLG GESGKST +KQMRI+H  G++ EE+K
Sbjct: 17  DEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKK 76

Query: 77  GFRPLVYQNIFVSMRAMIEAMERL--QIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAA 134
                + +N+  ++  ++ AM  +   +P + PE++  +  + S  P     + + +   
Sbjct: 77  QKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDH 136

Query: 135 MQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINE 194
           ++ LW D G++A +ER  E+ L+D A Y+L  ++ ++   Y PT QD+LR R+ T+GI E
Sbjct: 137 VKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFE 196

Query: 195 YCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKES 254
             F V K N  + DVGGQ+ ER+KWI CF +V A+IY+A+ S Y+  + E+N  NR++ES
Sbjct: 197 TRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRES 256

Query: 255 LALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFPSF------------QG 300
           L LF +I    W ++ S+ILFLNK D+L EK+    S +  YFP +             G
Sbjct: 257 LDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAG 316

Query: 301 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 360
                  AK FI D++ R+ T   DG             + H+TCA DT+NIR+VF D R
Sbjct: 317 EDPKVTRAKFFIRDLFLRISTATGDG---------KHYCYPHFTCAVDTENIRRVFNDCR 367

Query: 361 DSVLARYLDEINLL 374
           D +   +L +  LL
Sbjct: 368 DIIQRMHLKQYELL 381


>gi|117938765 GNAS complex locus isoform g [Homo sapiens]
          Length = 379

 Score =  243 bits (621), Expect = 2e-64
 Identities = 140/374 (37%), Positives = 207/374 (55%), Gaps = 25/374 (6%)

Query: 17  DEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERK 76
           +EKA    +++I + L + K+  R   +LLLLG GESGKST +KQMRI+H  G++ +E+ 
Sbjct: 15  EEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDEKA 74

Query: 77  GFRPLVYQNIFVSMRAMIEAMERLQIP--FSRPESKHHASLVMSQDPYKVTTFEKRYAAA 134
                +  N+  ++  ++ AM  L  P   + PE++     ++S        F   +   
Sbjct: 75  TKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEH 134

Query: 135 MQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINE 194
            + LW D G+RA YER  E+ L+D A Y+L  ++ I +  YVP+ QD+LR R+ T+GI E
Sbjct: 135 AKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFE 194

Query: 195 YCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKES 254
             F V K N  + DVGGQ+ ER+KWI CF +V A+I++ + S Y+  + E+NQ NR++E+
Sbjct: 195 TKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEA 254

Query: 255 LALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFPSF------------QG 300
           L LF +I    W ++ SVILFLNK D+L EK+    S +  YFP F             G
Sbjct: 255 LNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPG 314

Query: 301 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 360
                  AK FI D + R+ T   DG             + H+TCA DT+NIR+VF D R
Sbjct: 315 EDPRVTRAKYFIRDEFLRISTASGDG---------RHYCYPHFTCAVDTENIRRVFNDCR 365

Query: 361 DSVLARYLDEINLL 374
           D +   +L +  LL
Sbjct: 366 DIIQRMHLRQYELL 379


>gi|18426900 GNAS complex locus GNASS [Homo sapiens]
          Length = 380

 Score =  242 bits (617), Expect = 5e-64
 Identities = 140/375 (37%), Positives = 207/375 (55%), Gaps = 26/375 (6%)

Query: 17  DEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERK 76
           +EKA    +++I + L + K+  R   +LLLLG GESGKST +KQMRI+H  G++ +  K
Sbjct: 15  EEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEK 74

Query: 77  GFRPL-VYQNIFVSMRAMIEAMERLQIP--FSRPESKHHASLVMSQDPYKVTTFEKRYAA 133
             +   +  N+  ++  ++ AM  L  P   + PE++     ++S        F   +  
Sbjct: 75  ATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYE 134

Query: 134 AMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGIN 193
             + LW D G+RA YER  E+ L+D A Y+L  ++ I +  YVP+ QD+LR R+ T+GI 
Sbjct: 135 HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIF 194

Query: 194 EYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKE 253
           E  F V K N  + DVGGQ+ ER+KWI CF +V A+I++ + S Y+  + E+NQ NR++E
Sbjct: 195 ETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQE 254

Query: 254 SLALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFPSF------------Q 299
           +L LF +I    W ++ SVILFLNK D+L EK+    S +  YFP F             
Sbjct: 255 ALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEP 314

Query: 300 GPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDV 359
           G       AK FI D + R+ T   DG             + H+TCA DT+NIR+VF D 
Sbjct: 315 GEDPRVTRAKYFIRDEFLRISTASGDG---------RHYCYPHFTCAVDTENIRRVFNDC 365

Query: 360 RDSVLARYLDEINLL 374
           RD +   +L +  LL
Sbjct: 366 RDIIQRMHLRQYELL 380


>gi|4504047 GNAS complex locus GNASL [Homo sapiens]
          Length = 394

 Score =  236 bits (601), Expect = 3e-62
 Identities = 142/389 (36%), Positives = 209/389 (53%), Gaps = 40/389 (10%)

Query: 17  DEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYS----E 72
           +EKA    +++I + L + K+  R   +LLLLG GESGKST +KQMRI+H  G++    E
Sbjct: 15  EEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGE 74

Query: 73  EERKGFRPL-----------VYQNIFVSMRAMIEAMERLQIP--FSRPESKHHASLVMSQ 119
           E+ +  R             +  N+  ++  ++ AM  L  P   + PE++     ++S 
Sbjct: 75  EDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSV 134

Query: 120 DPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTA 179
                  F   +    + LW D G+RA YER  E+ L+D A Y+L  ++ I +  YVP+ 
Sbjct: 135 MNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSD 194

Query: 180 QDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYD 239
           QD+LR R+ T+GI E  F V K N  + DVGGQ+ ER+KWI CF +V A+I++ + S Y+
Sbjct: 195 QDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYN 254

Query: 240 QCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFPS 297
             + E+NQ NR++E+L LF +I    W ++ SVILFLNK D+L EK+    S +  YFP 
Sbjct: 255 MVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPE 314

Query: 298 F------------QGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTC 345
           F             G       AK FI D + R+ T   DG             + H+TC
Sbjct: 315 FARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDG---------RHYCYPHFTC 365

Query: 346 ATDTQNIRKVFKDVRDSVLARYLDEINLL 374
           A DT+NIR+VF D RD +   +L +  LL
Sbjct: 366 AVDTENIRRVFNDCRDIIQRMHLRQYELL 394


>gi|117938762 GNAS complex locus isoform f [Homo sapiens]
          Length = 395

 Score =  235 bits (600), Expect = 4e-62
 Identities = 142/390 (36%), Positives = 209/390 (53%), Gaps = 41/390 (10%)

Query: 17  DEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYS----E 72
           +EKA    +++I + L + K+  R   +LLLLG GESGKST +KQMRI+H  G++    E
Sbjct: 15  EEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGE 74

Query: 73  EERKGFRPL------------VYQNIFVSMRAMIEAMERLQIP--FSRPESKHHASLVMS 118
           E+ +  R              +  N+  ++  ++ AM  L  P   + PE++     ++S
Sbjct: 75  EDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 134

Query: 119 QDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPT 178
                   F   +    + LW D G+RA YER  E+ L+D A Y+L  ++ I +  YVP+
Sbjct: 135 VMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPS 194

Query: 179 AQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEY 238
            QD+LR R+ T+GI E  F V K N  + DVGGQ+ ER+KWI CF +V A+I++ + S Y
Sbjct: 195 DQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSY 254

Query: 239 DQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFP 296
           +  + E+NQ NR++E+L LF +I    W ++ SVILFLNK D+L EK+    S +  YFP
Sbjct: 255 NMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFP 314

Query: 297 SF------------QGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYT 344
            F             G       AK FI D + R+ T   DG             + H+T
Sbjct: 315 EFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDG---------RHYCYPHFT 365

Query: 345 CATDTQNIRKVFKDVRDSVLARYLDEINLL 374
           CA DT+NIR+VF D RD +   +L +  LL
Sbjct: 366 CAVDTENIRRVFNDCRDIIQRMHLRQYELL 395


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score =  228 bits (581), Expect = 7e-60
 Identities = 139/393 (35%), Positives = 214/393 (54%), Gaps = 44/393 (11%)

Query: 17   DEKAAARVDQEINRILLEQKKQDR-GEL---KLLLLGPGESGKSTFIKQMRIIHGAGYS- 71
            +++A  R +++ ++++ +Q + ++ G +   +LLLLG GESGKST +KQMRI+H  G++ 
Sbjct: 654  EKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG 713

Query: 72   ---EEERKGFRPL-----------VYQNIFVSMRAMIEAMERLQIP--FSRPESKHHASL 115
               EE+ +  R             +  N+  ++  ++ AM  L  P   + PE++     
Sbjct: 714  EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 773

Query: 116  VMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGY 175
            ++S        F   +    + LW D G+RA YER  E+ L+D A Y+L  ++ I +  Y
Sbjct: 774  ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 833

Query: 176  VPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASL 235
            VP+ QD+LR R+ T+GI E  F V K N  + DVGGQ+ ER+KWI CF +V A+I++ + 
Sbjct: 834  VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 893

Query: 236  SEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLAT 293
            S Y+  + E+NQ NR++E+L LF +I    W ++ SVILFLNK D+L EK+    S +  
Sbjct: 894  SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 953

Query: 294  YFPSF------------QGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFS 341
            YFP F             G       AK FI D + R+ T   DG             + 
Sbjct: 954  YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDG---------RHYCYP 1004

Query: 342  HYTCATDTQNIRKVFKDVRDSVLARYLDEINLL 374
            H+TCA DT+NIR+VF D RD +   +L +  LL
Sbjct: 1005 HFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 1037


>gi|4757774 ADP-ribosylation factor-like 3 [Homo sapiens]
          Length = 182

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 11/105 (10%)

Query: 188 PTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQ 247
           PT G N      Q   L + D+GGQ+  R  W + FEN   LIY+   ++  +  EE  Q
Sbjct: 47  PTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKR-FEETGQ 105

Query: 248 ENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLA 292
           E            +LE        V++F NK D+L    P S +A
Sbjct: 106 E---------LAELLEEEKLSCVPVLIFANKQDLL-TAAPASEIA 140


>gi|13376574 ADP-ribosylation factor-like 14 [Homo sapiens]
          Length = 192

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 13/104 (12%)

Query: 179 AQDVLRSRMPTTGINEYCFSVQKT-NLRIVDVGGQKSERKKWIHCFENVIALIYLASLSE 237
           A+D+  + +PT G N     +++  +L + DVGGQ+  R  W    EN   L+Y+     
Sbjct: 36  AKDI--TTIPTIGFNVEMIELERNLSLTVWDVGGQEKMRTVWGCYCENTDGLVYVV---- 89

Query: 238 YDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDI 281
                 ++  + R++ES   F  IL+    K+  V+L  NK D+
Sbjct: 90  ------DSTDKQRLEESQRQFEHILKNEHIKNVPVVLLANKQDM 127


>gi|4502209 ADP-ribosylation factor 5 [Homo sapiens]
          Length = 180

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 11/105 (10%)

Query: 187 MPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENN 246
           +PT G N      +     + DVGGQ   R  W H F+N   LI++           ++N
Sbjct: 46  IPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVV----------DSN 95

Query: 247 QENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHL 291
              R++ES      +L+    +   +++F NK D +   +P S L
Sbjct: 96  DRERVQESADELQKMLQEDELRDAVLLVFANKQD-MPNAMPVSEL 139


>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
           [Homo sapiens]
          Length = 569

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 17/145 (11%)

Query: 180 QDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYD 239
           QD     +PT G N      +     I DVGG+   R  W H + N  A++++   S  D
Sbjct: 426 QDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRD 485

Query: 240 QCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDI-----LEE--KIPTSHLA 292
           +  E +++       LA   T  EL   +   +++F NK D+     +EE  ++ + H  
Sbjct: 486 RISEAHSE-------LAKLLTEKEL---RDALLLIFANKQDVAGALSVEEITELLSLHKL 535

Query: 293 TYFPSFQGPKQDAEAAKRFILDMYT 317
               S+     DA +  + I D YT
Sbjct: 536 CCGRSWYIQGCDARSVFQIICDQYT 560


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)

Query: 180 QDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYD 239
           QD     +PT G N      +     I DVGG+   R  W H + N  A++++   S  D
Sbjct: 426 QDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRD 485

Query: 240 QCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDI 281
           +  E +++       LA   T  EL   +   +++F NK D+
Sbjct: 486 RISEAHSE-------LAKLLTEKEL---RDALLLIFANKQDV 517


>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
           [Homo sapiens]
          Length = 574

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)

Query: 180 QDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYD 239
           QD     +PT G N      +     I DVGG+   R  W H + N  A++++   S  D
Sbjct: 426 QDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRD 485

Query: 240 QCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDI 281
           +  E +++       LA   T  EL   +   +++F NK D+
Sbjct: 486 RISEAHSE-------LAKLLTEKEL---RDALLLIFANKQDV 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,592,038
Number of Sequences: 37866
Number of extensions: 575663
Number of successful extensions: 1578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1472
Number of HSP's gapped (non-prelim): 79
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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