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Search of human proteins with 155369269
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155369269 tetraspanin 19 [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155369269 tetraspanin 19 [Homo sapiens] 513 e-146
gi|4504813 CD82 antigen isoform 1 [Homo sapiens] 121 5e-28
gi|67782354 CD82 antigen isoform 2 [Homo sapiens] 105 5e-23
gi|4502663 CD37 antigen isoform A [Homo sapiens] 104 6e-23
gi|4502679 CD63 antigen isoform A [Homo sapiens] 76 2e-14
gi|91807110 CD37 antigen isoform B [Homo sapiens] 74 9e-14
gi|87159824 CD151 antigen [Homo sapiens] 74 2e-13
gi|87159822 CD151 antigen [Homo sapiens] 74 2e-13
gi|21237751 CD151 antigen [Homo sapiens] 74 2e-13
gi|21237748 CD151 antigen [Homo sapiens] 74 2e-13
gi|21265104 tetraspanin 7 [Homo sapiens] 73 3e-13
gi|91199546 CD63 antigen isoform B [Homo sapiens] 70 1e-12
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens] 70 1e-12
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens] 70 1e-12
gi|68800005 tetraspanin 4 isoform a [Homo sapiens] 67 1e-11
gi|4507543 tetraspanin 4 isoform a [Homo sapiens] 67 1e-11
gi|68800018 tetraspanin 4 isoform a [Homo sapiens] 67 1e-11
gi|68800024 tetraspanin 4 isoform a [Homo sapiens] 67 1e-11
gi|68800011 tetraspanin 4 isoform a [Homo sapiens] 67 1e-11
gi|68799997 tetraspanin 4 isoform a [Homo sapiens] 67 1e-11
gi|10834972 CD53 antigen [Homo sapiens] 65 5e-11
gi|91106727 CD53 antigen [Homo sapiens] 65 5e-11
gi|5729941 tetraspanin 9 [Homo sapiens] 64 1e-10
gi|21264578 tetraspan 1 [Homo sapiens] 63 3e-10
gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens] 63 3e-10
gi|122937466 tetraspanin 11 [Homo sapiens] 62 6e-10
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ... 60 2e-09
gi|30425534 tetraspanin 33 [Homo sapiens] 57 1e-08
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens] 56 3e-08
gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens] 54 1e-07
>gi|155369269 tetraspanin 19 [Homo sapiens]
Length = 248
Score = 513 bits (1321), Expect = e-146
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MLRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQIL 60
MLRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQIL
Sbjct: 1 MLRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQIL 60
Query: 61 IGMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHD 120
IGMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHD
Sbjct: 61 IGMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHD 120
Query: 121 KIDFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTK 180
KIDFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTK
Sbjct: 121 KIDFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTK 180
Query: 181 STLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNI 240
STLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNI
Sbjct: 181 STLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNI 240
Query: 241 KNIIHAEM 248
KNIIHAEM
Sbjct: 241 KNIIHAEM 248
>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
Length = 267
Score = 121 bits (304), Expect = 5e-28
Identities = 71/252 (28%), Positives = 123/252 (48%), Gaps = 23/252 (9%)
Query: 9 IIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTV 68
+ KYFL L N F +LG + +GFG W+L D+++F++ ++ + + + IG+G+ T+
Sbjct: 8 VTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTM 67
Query: 69 LFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISE 128
L LG IG NE+R LL +Y + QV A +++Q + +I +
Sbjct: 68 LMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRD 127
Query: 129 YGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQV--PCSC-------T 179
Y S + W + +Q ++CCG ++ +W N N +V PCSC
Sbjct: 128 YNSSREDSLQDAW---DYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDN 184
Query: 180 KSTLRKWFCDEPLNAT-----------YLEGCENKISAWYNVNVLTLIGINFGLLTSEVF 228
++RK FC+ P N T Y EGC K+ AW N+ ++G+ G+ E+
Sbjct: 185 SLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELL 244
Query: 229 QVSLTVCFFKNI 240
+ L++C +++
Sbjct: 245 GMVLSICLCRHV 256
>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
Length = 242
Score = 105 bits (261), Expect = 5e-23
Identities = 68/252 (26%), Positives = 119/252 (47%), Gaps = 48/252 (19%)
Query: 9 IIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTV 68
+ KYFL L N F +LG + +GFG W+L D+++F++ ++ + + + IG+G+ T+
Sbjct: 8 VTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTM 67
Query: 69 LFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISE 128
L LG IG NE+R LL + K+E+ + + +I +
Sbjct: 68 LMGFLGCIGAVNEVRCLLGLL---------------------KQEMGGI----VTELIRD 102
Query: 129 YGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQV--PCSC-------T 179
Y S + W + +Q ++CCG ++ +W N N +V PCSC
Sbjct: 103 YNSSREDSLQDAW---DYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDN 159
Query: 180 KSTLRKWFCDEPLNAT-----------YLEGCENKISAWYNVNVLTLIGINFGLLTSEVF 228
++RK FC+ P N T Y EGC K+ AW N+ ++G+ G+ E+
Sbjct: 160 SLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELL 219
Query: 229 QVSLTVCFFKNI 240
+ L++C +++
Sbjct: 220 GMVLSICLCRHV 231
>gi|4502663 CD37 antigen isoform A [Homo sapiens]
Length = 281
Score = 104 bits (260), Expect = 6e-23
Identities = 74/269 (27%), Positives = 127/269 (47%), Gaps = 39/269 (14%)
Query: 9 IIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPI---SQILIGMGS 65
+IKYFL + N F VLG L FG W+L+D+ +F++ VP+ S++L G
Sbjct: 10 LIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFV---GLAFVPLQIWSKVLAISGI 66
Query: 66 STVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFV 125
T+ LLG +G E+R LL +Y ++ FA Q+ L I T++ ++++ D ++
Sbjct: 67 FTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKT 126
Query: 126 ISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDW----IKNKNKENSGQVPCSC--- 178
I +YG+ PE+ + +Q L+CCG H DW I N + +VPCSC
Sbjct: 127 IQKYGT--NPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNL 184
Query: 179 -----------------------TKSTLRKWFCDEPLNA-TYLEGCENKISAWYNVNVLT 214
+S C P + Y EGC + W + N+++
Sbjct: 185 SATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLIS 244
Query: 215 LIGINFGLLTSEVFQVSLTVCFFKNIKNI 243
++GI G+ E+ ++L++ +N+ ++
Sbjct: 245 IVGICLGVGLLELGFMTLSIFLCRNLDHV 273
>gi|4502679 CD63 antigen isoform A [Homo sapiens]
Length = 238
Score = 76.3 bits (186), Expect = 2e-14
Identities = 59/235 (25%), Positives = 108/235 (45%), Gaps = 13/235 (5%)
Query: 10 IKYFLNLINGAFLV--LGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSST 67
+K+ L ++ AF +GL+ +G GA L+L + A + ++P+ ++I +G
Sbjct: 10 VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGS---LLPV--VIIAVGVFL 64
Query: 68 VLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVIS 127
L +G G E L+I +A+ ++ V+V + +++V +++ +
Sbjct: 65 FLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQME 124
Query: 128 EYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWF 187
Y P++ +IL+ +Q +CCG NYTDW K + + +VP SC +
Sbjct: 125 NY-----PKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKN-RVPDSCCINVTVGCG 178
Query: 188 CDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNIKN 242
+ A + EGC KI W NVL + G+ EV + C K+I++
Sbjct: 179 INFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRS 233
>gi|91807110 CD37 antigen isoform B [Homo sapiens]
Length = 213
Score = 74.3 bits (181), Expect = 9e-14
Identities = 51/203 (25%), Positives = 92/203 (45%), Gaps = 33/203 (16%)
Query: 72 LLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEYGS 131
LLG +G E+R LL +Y ++ FA Q+ L I T++ ++++ D ++ I +YG+
Sbjct: 5 LLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYGT 64
Query: 132 KDKPEDITKWTILNALQKTLQCCGQHNYTDW----IKNKNKENSGQVPCSC--------- 178
PE+ + +Q L+CCG H DW I N + +VPCSC
Sbjct: 65 --NPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDS 122
Query: 179 -----------------TKSTLRKWFCDEPLNA-TYLEGCENKISAWYNVNVLTLIGINF 220
+S C P + Y EGC + W + N+++++GI
Sbjct: 123 TILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICL 182
Query: 221 GLLTSEVFQVSLTVCFFKNIKNI 243
G+ E+ ++L++ +N+ ++
Sbjct: 183 GVGLLELGFMTLSIFLCRNLDHV 205
>gi|87159824 CD151 antigen [Homo sapiens]
Length = 253
Score = 73.6 bits (179), Expect = 2e-13
Identities = 52/243 (21%), Positives = 115/243 (47%), Gaps = 14/243 (5%)
Query: 7 TIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSS 66
T+ +KY L N F + GL M G W L ++++++ + + + IL+ G+
Sbjct: 13 TVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTY--LATAYILVVAGTV 70
Query: 67 TVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVI 126
++ +LG E R LL +Y +L+ F ++++ +++ + + +
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 127 SEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKN---KNKENSGQ-VPCSCTKST 182
++ + E +T + ++ LQ+ CCG +N DW + +++E G+ VP SC K+
Sbjct: 131 TKRYHQPGHEAVT--SAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTV 188
Query: 183 LRKWFCDEPLNATYL----EGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFK 238
+ C + +A+ + GC K+ + ++ + + G+ +VF + T C ++
Sbjct: 189 VA--LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYR 246
Query: 239 NIK 241
++K
Sbjct: 247 SLK 249
>gi|87159822 CD151 antigen [Homo sapiens]
Length = 253
Score = 73.6 bits (179), Expect = 2e-13
Identities = 52/243 (21%), Positives = 115/243 (47%), Gaps = 14/243 (5%)
Query: 7 TIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSS 66
T+ +KY L N F + GL M G W L ++++++ + + + IL+ G+
Sbjct: 13 TVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTY--LATAYILVVAGTV 70
Query: 67 TVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVI 126
++ +LG E R LL +Y +L+ F ++++ +++ + + +
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 127 SEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKN---KNKENSGQ-VPCSCTKST 182
++ + E +T + ++ LQ+ CCG +N DW + +++E G+ VP SC K+
Sbjct: 131 TKRYHQPGHEAVT--SAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTV 188
Query: 183 LRKWFCDEPLNATYL----EGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFK 238
+ C + +A+ + GC K+ + ++ + + G+ +VF + T C ++
Sbjct: 189 VA--LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYR 246
Query: 239 NIK 241
++K
Sbjct: 247 SLK 249
>gi|21237751 CD151 antigen [Homo sapiens]
Length = 253
Score = 73.6 bits (179), Expect = 2e-13
Identities = 52/243 (21%), Positives = 115/243 (47%), Gaps = 14/243 (5%)
Query: 7 TIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSS 66
T+ +KY L N F + GL M G W L ++++++ + + + IL+ G+
Sbjct: 13 TVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTY--LATAYILVVAGTV 70
Query: 67 TVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVI 126
++ +LG E R LL +Y +L+ F ++++ +++ + + +
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 127 SEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKN---KNKENSGQ-VPCSCTKST 182
++ + E +T + ++ LQ+ CCG +N DW + +++E G+ VP SC K+
Sbjct: 131 TKRYHQPGHEAVT--SAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTV 188
Query: 183 LRKWFCDEPLNATYL----EGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFK 238
+ C + +A+ + GC K+ + ++ + + G+ +VF + T C ++
Sbjct: 189 VA--LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYR 246
Query: 239 NIK 241
++K
Sbjct: 247 SLK 249
>gi|21237748 CD151 antigen [Homo sapiens]
Length = 253
Score = 73.6 bits (179), Expect = 2e-13
Identities = 52/243 (21%), Positives = 115/243 (47%), Gaps = 14/243 (5%)
Query: 7 TIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSS 66
T+ +KY L N F + GL M G W L ++++++ + + + IL+ G+
Sbjct: 13 TVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTY--LATAYILVVAGTV 70
Query: 67 TVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVI 126
++ +LG E R LL +Y +L+ F ++++ +++ + + +
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 127 SEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKN---KNKENSGQ-VPCSCTKST 182
++ + E +T + ++ LQ+ CCG +N DW + +++E G+ VP SC K+
Sbjct: 131 TKRYHQPGHEAVT--SAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTV 188
Query: 183 LRKWFCDEPLNATYL----EGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFK 238
+ C + +A+ + GC K+ + ++ + + G+ +VF + T C ++
Sbjct: 189 VA--LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYR 246
Query: 239 NIK 241
++K
Sbjct: 247 SLK 249
>gi|21265104 tetraspanin 7 [Homo sapiens]
Length = 249
Score = 72.8 bits (177), Expect = 3e-13
Identities = 51/235 (21%), Positives = 105/235 (44%), Gaps = 12/235 (5%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+K L + + F + G++ + G W L +++ EN+ +LIG G++ V+
Sbjct: 15 LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENS---TNAPYVLIGTGTTIVV 71
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
F L G W+L +YA+ ++ F ++V + E++ + + Y
Sbjct: 72 FGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTY 131
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKST--LRKWF 187
D+ + ++ +Q++L CCG NYT+W + G P C T +
Sbjct: 132 NGNDE-----RSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDL 186
Query: 188 CDEPLNATYL--EGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNI 240
+ + AT + +GC + ++++ N+ + G+ FG+ S++ + L C + I
Sbjct: 187 HNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFI 241
>gi|91199546 CD63 antigen isoform B [Homo sapiens]
Length = 236
Score = 70.5 bits (171), Expect = 1e-12
Identities = 58/235 (24%), Positives = 108/235 (45%), Gaps = 15/235 (6%)
Query: 10 IKYFLNLINGAFLV--LGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSST 67
+K+ L ++ AF +GL+ +G GA L+L + A + ++P+ ++I +G
Sbjct: 10 VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGS---LLPV--VIIAVGVFL 64
Query: 68 VLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVIS 127
L +G G E L+I +A+ ++ V+V + +++V +++ +
Sbjct: 65 FLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQME 124
Query: 128 EYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWF 187
Y P++ +IL+ +Q +CCG NYTDW K + + +VP SC +
Sbjct: 125 NY-----PKNNHTASILDRMQADFKCCGAANYTDWEKIPSM-SKNRVPDSCCINVTVGCG 178
Query: 188 CDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNIKN 242
+ A + EGC KI W NVL + G+ + V + C K+I++
Sbjct: 179 INFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGI--AFVLGIVFACCLVKSIRS 231
>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
Length = 294
Score = 70.5 bits (171), Expect = 1e-12
Identities = 57/258 (22%), Positives = 116/258 (44%), Gaps = 37/258 (14%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+K+ L + + F ++G L + G + ++R + T + F+ P + ILI +G V+
Sbjct: 20 LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL---ESAFLAP-AIILILLG---VV 72
Query: 70 FCLLGYIGIHNEIR---WLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVI 126
++ +IG+ +R +LL + ++ ++++ +T + + +D I I
Sbjct: 73 MFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGI 132
Query: 127 SEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCT------- 179
Y +D+ I++ +QK +CCG +Y DW KN+ + S P +C
Sbjct: 133 ENYY-----DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCI 187
Query: 180 -------------KSTLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSE 226
K+ ++ F + + Y+ GC N + W+ N + GI G+L +
Sbjct: 188 RNTTEVVNTMCGYKTIDKERFSVQ--DVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQ 245
Query: 227 VFQVSLTVCFFKNIKNII 244
V LT+ + +++II
Sbjct: 246 FLGVLLTLLYITRVEDII 263
>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
Length = 245
Score = 70.5 bits (171), Expect = 1e-12
Identities = 49/222 (22%), Positives = 91/222 (40%), Gaps = 10/222 (4%)
Query: 21 FLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVLFCLLGYIGIHN 80
F + G++ + G W + N+ + +E + +LI G+ +L G
Sbjct: 28 FWITGVILLAVGIWGKVSLENYFSLLNEK---ATNVPFVLIATGTVIILLGTFGCFATCR 84
Query: 81 EIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEYGSKDKPEDITK 140
W+L +YA+ +T F V++V + + E++ + + + + +Y S +
Sbjct: 85 ASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGD----YR 140
Query: 141 WTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCDEPLNATYLEGC 200
++ +Q TL CCG +Y DW G P SC K L + EGC
Sbjct: 141 SHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKG-FPKSCCK--LEDCTPQRDADKVNNEGC 197
Query: 201 ENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNIKN 242
K+ + + GI+FG+ ++ + L C + I N
Sbjct: 198 FIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITN 239
>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 67.4 bits (163), Expect = 1e-11
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 11/224 (4%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+KY + N F + G +G G WL + +F T ++ + + +LI G+ +
Sbjct: 9 VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL--SSSFPSLSAANLLIITGAFVMA 66
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
+G +G E + LL+ + +L+ F ++ ++ +++ + + + Y
Sbjct: 67 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 126
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCD 189
G++ W+I+ Q +CCG NYTDW + N+ +VP SC
Sbjct: 127 GTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFE---VYNATRVPDSCCLEFSESCGLH 180
Query: 190 EPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLT 233
P + C + W N+L +GI FGL T+ V + LT
Sbjct: 181 AP-GTWWKAPCYETVKVWLQENLLA-VGI-FGLCTALVQILGLT 221
>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 67.4 bits (163), Expect = 1e-11
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 11/224 (4%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+KY + N F + G +G G WL + +F T ++ + + +LI G+ +
Sbjct: 9 VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL--SSSFPSLSAANLLIITGAFVMA 66
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
+G +G E + LL+ + +L+ F ++ ++ +++ + + + Y
Sbjct: 67 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 126
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCD 189
G++ W+I+ Q +CCG NYTDW + N+ +VP SC
Sbjct: 127 GTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFE---VYNATRVPDSCCLEFSESCGLH 180
Query: 190 EPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLT 233
P + C + W N+L +GI FGL T+ V + LT
Sbjct: 181 AP-GTWWKAPCYETVKVWLQENLLA-VGI-FGLCTALVQILGLT 221
>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 67.4 bits (163), Expect = 1e-11
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 11/224 (4%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+KY + N F + G +G G WL + +F T ++ + + +LI G+ +
Sbjct: 9 VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL--SSSFPSLSAANLLIITGAFVMA 66
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
+G +G E + LL+ + +L+ F ++ ++ +++ + + + Y
Sbjct: 67 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 126
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCD 189
G++ W+I+ Q +CCG NYTDW + N+ +VP SC
Sbjct: 127 GTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFE---VYNATRVPDSCCLEFSESCGLH 180
Query: 190 EPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLT 233
P + C + W N+L +GI FGL T+ V + LT
Sbjct: 181 AP-GTWWKAPCYETVKVWLQENLLA-VGI-FGLCTALVQILGLT 221
>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 67.4 bits (163), Expect = 1e-11
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 11/224 (4%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+KY + N F + G +G G WL + +F T ++ + + +LI G+ +
Sbjct: 9 VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL--SSSFPSLSAANLLIITGAFVMA 66
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
+G +G E + LL+ + +L+ F ++ ++ +++ + + + Y
Sbjct: 67 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 126
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCD 189
G++ W+I+ Q +CCG NYTDW + N+ +VP SC
Sbjct: 127 GTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFE---VYNATRVPDSCCLEFSESCGLH 180
Query: 190 EPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLT 233
P + C + W N+L +GI FGL T+ V + LT
Sbjct: 181 AP-GTWWKAPCYETVKVWLQENLLA-VGI-FGLCTALVQILGLT 221
>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 67.4 bits (163), Expect = 1e-11
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 11/224 (4%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+KY + N F + G +G G WL + +F T ++ + + +LI G+ +
Sbjct: 9 VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL--SSSFPSLSAANLLIITGAFVMA 66
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
+G +G E + LL+ + +L+ F ++ ++ +++ + + + Y
Sbjct: 67 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 126
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCD 189
G++ W+I+ Q +CCG NYTDW + N+ +VP SC
Sbjct: 127 GTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFE---VYNATRVPDSCCLEFSESCGLH 180
Query: 190 EPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLT 233
P + C + W N+L +GI FGL T+ V + LT
Sbjct: 181 AP-GTWWKAPCYETVKVWLQENLLA-VGI-FGLCTALVQILGLT 221
>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 67.4 bits (163), Expect = 1e-11
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 11/224 (4%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+KY + N F + G +G G WL + +F T ++ + + +LI G+ +
Sbjct: 9 VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL--SSSFPSLSAANLLIITGAFVMA 66
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
+G +G E + LL+ + +L+ F ++ ++ +++ + + + Y
Sbjct: 67 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 126
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCD 189
G++ W+I+ Q +CCG NYTDW + N+ +VP SC
Sbjct: 127 GTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFE---VYNATRVPDSCCLEFSESCGLH 180
Query: 190 EPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLT 233
P + C + W N+L +GI FGL T+ V + LT
Sbjct: 181 AP-GTWWKAPCYETVKVWLQENLLA-VGI-FGLCTALVQILGLT 221
>gi|10834972 CD53 antigen [Homo sapiens]
Length = 219
Score = 65.1 bits (157), Expect = 5e-11
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 29/226 (12%)
Query: 9 IIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTV 68
++KY L N F + G +GFG +LL+ NNF F +N + + + + +GS +
Sbjct: 8 LLKYVLFFFNLLFWICGCCILGFGIYLLI-HNNFGVLF--HNLPSLTLGNVFVIVGSIIM 64
Query: 69 LFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISE 128
+ LG +G E + LL+ + +L+ +V L+ + ++++ + + I
Sbjct: 65 VVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHR 124
Query: 129 YGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFC 188
Y S + + W +++Q LQCCG + +DW P SC RK
Sbjct: 125 YHSDNSTK--AAW---DSIQSFLQCCGINGTSDWTSGP--------PASCPSD--RK--- 166
Query: 189 DEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTV 234
+EGC K W++ N L + I + EV +S +
Sbjct: 167 --------VEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFAL 204
>gi|91106727 CD53 antigen [Homo sapiens]
Length = 219
Score = 65.1 bits (157), Expect = 5e-11
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 29/226 (12%)
Query: 9 IIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTV 68
++KY L N F + G +GFG +LL+ NNF F +N + + + + +GS +
Sbjct: 8 LLKYVLFFFNLLFWICGCCILGFGIYLLI-HNNFGVLF--HNLPSLTLGNVFVIVGSIIM 64
Query: 69 LFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISE 128
+ LG +G E + LL+ + +L+ +V L+ + ++++ + + I
Sbjct: 65 VVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHR 124
Query: 129 YGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFC 188
Y S + + W +++Q LQCCG + +DW P SC RK
Sbjct: 125 YHSDNSTK--AAW---DSIQSFLQCCGINGTSDWTSGP--------PASCPSD--RK--- 166
Query: 189 DEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTV 234
+EGC K W++ N L + I + EV +S +
Sbjct: 167 --------VEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFAL 204
>gi|5729941 tetraspanin 9 [Homo sapiens]
Length = 239
Score = 63.9 bits (154), Expect = 1e-10
Identities = 50/234 (21%), Positives = 103/234 (44%), Gaps = 15/234 (6%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+KY + L N F + G +G G WL + + NF T + + + ++I +G+ ++
Sbjct: 9 LKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATF--SPSFPSLSAANLVIAIGTIVMV 66
Query: 70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEY 129
LG +G E + LL+ + +++ +++L ++V + + + Y
Sbjct: 67 TGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLY 126
Query: 130 GSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCD 189
+++ W N +Q ++CCG +YTDW + VP C + C
Sbjct: 127 HTENNVGLKNAW---NIIQAEMRCCGVTDYTDWYPVLGENT---VPDRCCMENSQG--CG 178
Query: 190 EPLNAT---YLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNI 240
NAT + GC K+ W++ N L + +L ++ ++ ++ F++I
Sbjct: 179 R--NATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHI 230
>gi|21264578 tetraspan 1 [Homo sapiens]
Length = 241
Score = 62.8 bits (151), Expect = 3e-10
Identities = 59/242 (24%), Positives = 103/242 (42%), Gaps = 17/242 (7%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAF---DENNHFIVPISQILIGMGSS 66
IK + L N + G + G W+ +D +FL F + V + LI G
Sbjct: 7 IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
Query: 67 TVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQV---VLSAFIITKKEEVQQLWHDKID 123
LG G E + L+ + ++ F +V V++ T E L +
Sbjct: 67 VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLL--VVP 124
Query: 124 FVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKN-KENSGQVPCSC---T 179
+ +YGS+ ED T+ + N K L+CCG NYTD+ + KENS P C
Sbjct: 125 AIKKDYGSQ---EDFTQ--VWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNV 179
Query: 180 KSTLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKN 239
+T + + + +EGC N++ N +T+ G+ G+ E+ + +++ + N
Sbjct: 180 TNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCN 239
Query: 240 IK 241
++
Sbjct: 240 LQ 241
>gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens]
Length = 245
Score = 62.8 bits (151), Expect = 3e-10
Identities = 58/222 (26%), Positives = 98/222 (44%), Gaps = 18/222 (8%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69
+K L+L+NG V G++ +G G + ++ +++ + + + MG TVL
Sbjct: 11 LKKLLSLLNGFVAVSGIILVGLGIGGKCGGASLTNVLGLSSAYLLHVGNLCLVMGCITVL 70
Query: 70 FCLLGYIGIHNEIRWLLI-----VYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDF 124
G+ G E R L+ + VLI A VVL F I ++ +
Sbjct: 71 LGCAGWYGATKESRGTLLFCILSMVIVLIMEVTAATVVLLFFPIVGDVALEHTFVT---- 126
Query: 125 VISEYGSKDKPEDI-TKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQV-PCSCTKST 182
+ Y ++P+D T+W N + + L+CCG +NYTD+ + + +G P SC KS
Sbjct: 127 LRKNYRGYNEPDDYSTQW---NLVMEKLKCCGVNNYTDFSGSSFEMTTGHTYPRSCCKS- 182
Query: 183 LRKWFC---DEPLNATYLEGCENKISAWYNVNVLTLIGINFG 221
+ C D N + +GC +K+ TL G + G
Sbjct: 183 IGSVSCDGRDVSPNVIHQKGCFHKLLKITKTQSFTLSGSSLG 224
>gi|122937466 tetraspanin 11 [Homo sapiens]
Length = 253
Score = 61.6 bits (148), Expect = 6e-10
Identities = 54/242 (22%), Positives = 105/242 (43%), Gaps = 14/242 (5%)
Query: 8 IIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSST 67
I +KY L + N F V G + G W L++++ +L+ + + ILI G
Sbjct: 14 IYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASST--FAASAYILIFAGVLV 71
Query: 68 VLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVIS 127
++ LG+ I E + L Y L+ F V++V + + ++ ++
Sbjct: 72 MVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLA 131
Query: 128 EYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNK----NKENSGQVPCSCTKSTL 183
E + IT ++ LQ+ +CCG ++ DW + + QVP SC K+ +
Sbjct: 132 ENYGQPGATQIT--ASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVV 189
Query: 184 RKWFCDE---PLNATYLE-GCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKN 239
+ C + P N +E GC K+ + ++L + + G+ ++ + LT C +
Sbjct: 190 VR--CGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQR 247
Query: 240 IK 241
++
Sbjct: 248 LQ 249
>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
sapiens]
Length = 253
Score = 60.1 bits (144), Expect = 2e-09
Identities = 54/206 (26%), Positives = 101/206 (49%), Gaps = 19/206 (9%)
Query: 2 LRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILI 61
+ ++KT+++ FLNLI F + GA++ + +++ F E+ + ++P + ++I
Sbjct: 6 ITSSKTVLV--FLNLI---FWGAAGILCYVGAYVFITYDDY-DHFFEDVYTLIP-AVVII 58
Query: 62 GMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDK 121
+G+ + L+G E R L + +++ F +VV+ + +V+
Sbjct: 59 AVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRS 118
Query: 122 IDFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKN--KENSGQ-VPCSC 178
I V Y + P+ ++ ++ +Q+ L CCG HNY+DW +N + KE Q VP SC
Sbjct: 119 IQKVYKTYNGTN-PDAASR--AIDYVQRQLHCCGIHNYSDW-ENTDWFKETKNQSVPLSC 174
Query: 179 TKSTLRKWFCDEPL---NATYLEGCE 201
+ T C+ L + Y EGCE
Sbjct: 175 CRETASN--CNGSLAHPSDLYAEGCE 198
>gi|30425534 tetraspanin 33 [Homo sapiens]
Length = 283
Score = 57.4 bits (137), Expect = 1e-08
Identities = 58/261 (22%), Positives = 107/261 (40%), Gaps = 30/261 (11%)
Query: 9 IIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTV 68
++KY L N F V+ ++ + G + L ++ A V + +LI +G
Sbjct: 21 LVKYLLFFFNMLFWVISMVMVAVGVYARLMKH----AEAALACLAVDPAILLIVVGVLMF 76
Query: 69 LFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISE 128
L G IG E LL +++ +T F +Q+ ++ + + I+ I
Sbjct: 77 LLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH 136
Query: 129 YGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNK----NKENSGQ----VPCSCTK 180
Y +D+ +++ QK CCG +Y DW +N +++N + VP SC
Sbjct: 137 YR-----DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCL 191
Query: 181 ST----LRKWFCDEPLNA---------TYLEGCENKISAWYNVNVLTLIGINFGLLTSEV 227
T + C + + A Y GC +K+ W + N+ L G+ GL ++
Sbjct: 192 PTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQL 251
Query: 228 FQVSLTVCFFKNIKNIIHAEM 248
+ L+ IK+ I ++
Sbjct: 252 VGILLSQILVNQIKDQIKLQL 272
>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
Length = 268
Score = 56.2 bits (134), Expect = 3e-08
Identities = 59/262 (22%), Positives = 105/262 (40%), Gaps = 38/262 (14%)
Query: 10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDR---NNFLTAFDENNHFIVPISQILIGMGSS 66
IKYF+ N F LG+ F+G G W ++ +N + D P+ L+ +G
Sbjct: 15 IKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGG--FDPVWLFLV-VGGV 71
Query: 67 TVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVI 126
+ G IG E +LL ++V + F +++ K+ ++ D++ F I
Sbjct: 72 MFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIK----DQLYFFI 127
Query: 127 SEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDW---------IKNKNKENSGQVPCS 177
+ + +DI +++ Q+ QCCG DW N ++E G
Sbjct: 128 NN-NIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSC 186
Query: 178 CTK-------------STLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLT 224
CTK +K D+ + Y +GC + W N+ + GI G+
Sbjct: 187 CTKDPAEDVINTQCGYDARQKPEVDQQI-VIYTKGCVPQFEKWLQDNLTIVAGIFIGIAL 245
Query: 225 SEVFQVSLTVCFFKNIKNIIHA 246
++F +C +N+ + I A
Sbjct: 246 LQIF----GICLAQNLVSDIEA 263
>gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]
Length = 305
Score = 53.9 bits (128), Expect = 1e-07
Identities = 52/247 (21%), Positives = 97/247 (39%), Gaps = 18/247 (7%)
Query: 1 MLRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENN-------HFI 53
M R + ++ L +N F ++ + + AW+ NN LT E +
Sbjct: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
Query: 54 VPISQILIGMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEE 113
+ ++I + ++ +LGY G LL Y + F V++ + ++
Sbjct: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM 120
Query: 114 VQQLWHDKIDFV--ISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENS 171
V W D + ++ YG W N Q+ +CCG +TDW++ +
Sbjct: 121 VPVQWSDMVTLKARMTNYGLPRYRWLTHAW---NFFQREFKCCGVVYFTDWLEMTEMDWP 177
Query: 172 GQVPCSCTKSTLRKWFCDEPLNATYLEGCENKISAWY----NVNVLTLIGINFGLLTSEV 227
C K E L+ Y EGC K+ ++ + VL +GI+ G+ +++
Sbjct: 178 PDSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGV--TQI 235
Query: 228 FQVSLTV 234
+ LT+
Sbjct: 236 LAMILTI 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,734,922
Number of Sequences: 37866
Number of extensions: 360562
Number of successful extensions: 1258
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1140
Number of HSP's gapped (non-prelim): 61
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.