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Search of human proteins with 153791707
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791707 sorting nexin family member 30 [Homo sapiens]
(437 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791707 sorting nexin family member 30 [Homo sapiens] 878 0.0
gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 381 e-106
gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 319 3e-87
gi|4507145 sorting nexin 4 [Homo sapiens] 107 3e-23
gi|23111038 sorting nexin 2 [Homo sapiens] 100 3e-21
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 85 1e-16
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 81 2e-15
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 80 4e-15
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 74 3e-13
gi|4507143 sorting nexin 3 isoform a [Homo sapiens] 72 8e-13
gi|23397574 sorting nexin 33 [Homo sapiens] 72 1e-12
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 71 2e-12
gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 71 2e-12
gi|23111030 sorting nexin 12 [Homo sapiens] 68 1e-11
gi|7706706 sorting nexin 9 [Homo sapiens] 67 4e-11
gi|23111047 sorting nexin 5 [Homo sapiens] 66 5e-11
gi|7657599 sorting nexin 5 [Homo sapiens] 66 5e-11
gi|23111026 sorting nexin 11 [Homo sapiens] 61 2e-09
gi|23111028 sorting nexin 11 [Homo sapiens] 61 2e-09
gi|23943858 sorting nexin 8 [Homo sapiens] 57 3e-08
gi|23111023 sorting nexin 10 [Homo sapiens] 54 2e-07
gi|72534838 sorting nexin 6B [Homo sapiens] 53 5e-07
gi|88703041 sorting nexin 6 isoform b [Homo sapiens] 44 2e-04
gi|31543452 PX domain containing serine/threonine kinase [Homo s... 41 0.002
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 40 0.003
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 40 0.003
gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 is... 40 0.003
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H... 40 0.005
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 40 0.005
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 40 0.005
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 878 bits (2268), Expect = 0.0
Identities = 437/437 (100%), Positives = 437/437 (100%)
Query: 1 MAGGPPKALPSTGPHSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGG 60
MAGGPPKALPSTGPHSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGG
Sbjct: 1 MAGGPPKALPSTGPHSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGG 60
Query: 61 TPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRV 120
TPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRV
Sbjct: 61 TPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRV 120
Query: 121 EFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKAL 180
EFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKAL
Sbjct: 121 EFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKAL 180
Query: 181 DKFLKRITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTGGYKLRTRPL 240
DKFLKRITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTGGYKLRTRPL
Sbjct: 181 DKFLKRITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTGGYKLRTRPL 240
Query: 241 EFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEG 300
EFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEG
Sbjct: 241 EFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEG 300
Query: 301 VSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVAL 360
VSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVAL
Sbjct: 301 VSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVAL 360
Query: 361 RKEDRPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCL 420
RKEDRPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCL
Sbjct: 361 RKEDRPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCL 420
Query: 421 MAWESIIPLLQEKQEAK 437
MAWESIIPLLQEKQEAK
Sbjct: 421 MAWESIIPLLQEKQEAK 437
>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
Length = 451
Score = 381 bits (978), Expect = e-106
Identities = 179/363 (49%), Positives = 264/363 (72%), Gaps = 5/363 (1%)
Query: 68 PASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEY 127
P S S++N+++ +D+ D +DLF+ VD+P+ HV T+ET+ITYRI TK++R EFD E+
Sbjct: 75 PTSPLSMINQIKFEDEPD--LKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEF 132
Query: 128 SVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRI 187
VRRRYQDF WL+ KLEE+ PT +IPPLPEKF+VKG+V+RF+++F+ETRRKAL KFL RI
Sbjct: 133 EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRI 192
Query: 188 TDHPVLSFNEHFNIFLTAK--DLNAYKKQGIALLTRMGESVKHVTGGYK-LRTRPLEFAA 244
DHP L+FNE F IFLTA+ +L+++KKQG LL+RMG++V+ V + ++ RP EF
Sbjct: 193 ADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFME 252
Query: 245 IGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSAC 304
+ ++++ F+ K+ ID+I+QRI KEE EY E++EYGP++ WSA E +L + L+ V++C
Sbjct: 253 MNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASC 312
Query: 305 IGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKED 364
I C A E+ ++E LPV+ EY+LYS+ + V+K+RDQ+QAE ++K+E + +K D
Sbjct: 313 IDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKAD 372
Query: 365 RPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWE 424
+P ++ K +D++EC N LKAD ERW+ N + D + MA++NI YYE+CL WE
Sbjct: 373 TDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWE 432
Query: 425 SII 427
S +
Sbjct: 433 SFL 435
>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
Length = 336
Score = 319 bits (818), Expect = 3e-87
Identities = 152/300 (50%), Positives = 224/300 (74%), Gaps = 5/300 (1%)
Query: 68 PASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEY 127
P S S++N+++ +D+ D +DLF+ VD+P+ HV T+ET+ITYRI TK++R EFD E+
Sbjct: 11 PTSPLSMINQIKFEDEPD--LKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEF 68
Query: 128 SVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRI 187
VRRRYQDF WL+ KLEE+ PT +IPPLPEKF+VKG+V+RF+++F+ETRRKAL KFL RI
Sbjct: 69 EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRI 128
Query: 188 TDHPVLSFNEHFNIFLTAK--DLNAYKKQGIALLTRMGESVKHVTGGYK-LRTRPLEFAA 244
DHP L+FNE F IFLTA+ +L+++KKQG LL+RMG++V+ V + ++ RP EF
Sbjct: 129 ADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFME 188
Query: 245 IGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSAC 304
+ ++++ F+ K+ ID+I+QRI KEE EY E++EYGP++ WSA E +L + L+ V++C
Sbjct: 189 MNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASC 248
Query: 305 IGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKED 364
I C A E+ ++E LPV+ EY+LYS+ + V+K+RDQ+QAE ++K+E + +K D
Sbjct: 249 IDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKAD 308
>gi|4507145 sorting nexin 4 [Homo sapiens]
Length = 450
Score = 107 bits (266), Expect = 3e-23
Identities = 88/365 (24%), Positives = 163/365 (44%), Gaps = 49/365 (13%)
Query: 106 ETYITYRITTKS---TRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEK---F 159
ETY Y I T+S T + L + S+ RRY +F+ LRS L P ++PPLPEK F
Sbjct: 78 ETYTAYLIETRSVEHTDGQSVLTD-SLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEF 136
Query: 160 VV-KGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYKKQGIAL 218
V K D +FVE RR L+ FL RI HP+L ++ F +FLT +
Sbjct: 137 VWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNETGF 196
Query: 219 LTRMGESVKHVTGGYKLRTRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELR 278
+ +K + ++++ F + Y D + + R+ R+
Sbjct: 197 QLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHG 256
Query: 279 EYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMK 338
YG V+S WSA+E E+ + L+ + +++++++ +D E + L+EY+ Y+++++
Sbjct: 257 NYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALR 315
Query: 339 SVLKKRDQVQAEYEAKLEAVALRKEDRPKV--------------------------PADV 372
+V +K + +Q + E + +A +K+ ++ A +
Sbjct: 316 AVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARI 375
Query: 373 EKCQDRMECFNADLK--------------ADMERWQNNKRQDFRQLLMGMADKNIQYYEK 418
+ ++++ LK AD+ER++ K +D ++ L+ A I +K
Sbjct: 376 KVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKK 435
Query: 419 CLMAW 423
+ W
Sbjct: 436 GIQVW 440
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 100 bits (249), Expect = 3e-21
Identities = 95/398 (23%), Positives = 183/398 (45%), Gaps = 56/398 (14%)
Query: 76 NRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQD 135
+R +++++ +G+ D+ + V DP+K M Y+ YR+TTK++ F E+SV+RR+ D
Sbjct: 127 SREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSD 186
Query: 136 FDWLRSKLEES--QPTHLIPPLPEKFVV------KGVVDRFSEEFVETRRKALDKFLKRI 187
F L SKL +++PP PEK +V G D S EFVE RR AL+++L+R
Sbjct: 187 FLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRT 246
Query: 188 TDHPVLSFNEHFNIFLTAKDL----NAYKKQGIALLTRMGESVKHVTGGYKLRTRPLEFA 243
HP L + FL + +L N G +L + ++ V K+ + E
Sbjct: 247 VKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVN---KMTIKMNESD 303
Query: 244 AIGDYLDTFALKLGTIDRIAQRIIK--EEIEYLV----ELREYGPVYSTWSALEGELAEP 297
A F K + + Q++ K +E LV EL ++ +A+ G +E
Sbjct: 304 A------WFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGN-SED 356
Query: 298 LEGVSACIGNCSTALEELTDDMTED--------FLPVLREYI------------------ 331
+S + + +EE D + ++ F +L +YI
Sbjct: 357 HTALSRALSQLA-EVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQ 415
Query: 332 LYSDSMKSVLKKRD-QVQAEYEAKLEAVALRKEDRPKVPADVEKCQDRMECFNADLKADM 390
+ D+ ++LKKR+ + + K + + K + + A V++ + E + ++ ++
Sbjct: 416 KWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEV 475
Query: 391 ERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIP 428
R++ + +DF+ +++ + +Q ++ + WE+ +P
Sbjct: 476 GRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLP 513
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 85.1 bits (209), Expect = 1e-16
Identities = 83/386 (21%), Positives = 169/386 (43%), Gaps = 38/386 (9%)
Query: 79 QLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDW 138
+L+++ + DL V + DP+K M Y+ Y++TT+++ F +++V+RR+ DF
Sbjct: 133 ELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLG 192
Query: 139 LRSKLEE--SQPTHLIPPLPEKFVV------KGVVDRFSEEFVETRRKALDKFLKRITDH 190
L KL E SQ ++PP PEK ++ G D S EF+E RR AL+++L+RI +H
Sbjct: 193 LYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNH 252
Query: 191 PVLSFNEHFNIFLTAKDL----NAYKKQGIALLTRMGESVKHVTG-GYKLRTRPLEFAAI 245
P + + FL ++L G LL ++ V+ K+ + F
Sbjct: 253 PTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEK 312
Query: 246 GDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACI 305
++ +L + + + ++ E + ++ + + E A L + +
Sbjct: 313 LQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTA--LSRALSQL 370
Query: 306 GNCSTALEEL-TDDMTEDFL---PVLREYI--------LYSDSMKSVLKKRD---QVQAE 350
+E+L + DF +L +YI + MK+ + +D +Q +
Sbjct: 371 AEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKK 430
Query: 351 YEAKLEAVALRKEDRPKVPAD--------VEKCQDRMECFNADLKADMERWQNNKRQDFR 402
EA+ + K D+ + D V + + E + ++ ++ R++ K +DF+
Sbjct: 431 REAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFK 490
Query: 403 QLLMGMADKNIQYYEKCLMAWESIIP 428
++ + + ++ WE+ +P
Sbjct: 491 NHVIKYLETLLYSQQQLAKYWEAFLP 516
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 80.9 bits (198), Expect = 2e-15
Identities = 73/363 (20%), Positives = 156/363 (42%), Gaps = 40/363 (11%)
Query: 79 QLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDW 138
+L+++ + DL V + DP+K M Y+ Y++TT+++ F +++V+RR+ DF
Sbjct: 133 ELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLG 192
Query: 139 LRSKLEE--SQPTHLIPPLPEKFVV------KGVVDRFSEEFVETRRKALDKFLKRITDH 190
L KL E SQ ++PP PEK ++ G D S EF+E RR AL+++L+RI +H
Sbjct: 193 LYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNH 252
Query: 191 PVLSFNEHFNIFLTAKDL----NAYKKQGIALLTRMGESVKHVTG-GYKLRTRPLEFAAI 245
P + + FL ++L G LL ++ V+ K+ + F
Sbjct: 253 PTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEK 312
Query: 246 GDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACI 305
++ +L + + + ++ E + ++ + + E A L + +
Sbjct: 313 LQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTA--LSRALSQL 370
Query: 306 GNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDR 365
+E+L + + +L E + + ++++ +V +YE E +
Sbjct: 371 AEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRWESRV-TQYERDFERI------- 422
Query: 366 PKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWES 425
+ ++ ++ R++ K +DF+ ++ + + ++ WE+
Sbjct: 423 -----------------STVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEA 465
Query: 426 IIP 428
+P
Sbjct: 466 FLP 468
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 80.1 bits (196), Expect = 4e-15
Identities = 96/450 (21%), Positives = 185/450 (41%), Gaps = 57/450 (12%)
Query: 21 PHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTSSPASSSSLL----- 75
P P SE A GG + D S + + I + SP ++SLL
Sbjct: 17 PFPGLEPESEGAAGGSEPEAGD-----SDTEGEDIFTGAAVVSKHQSPKITTSLLPINNG 71
Query: 76 -NRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQ 134
+ ++ D E +DLF M Y+ Y++TT+++ F +++V+RR+
Sbjct: 72 SKENGIHEEQDQEPQDLFAGDG--------MNAYVAYKVTTQTSLPLFRSKQFAVKRRFS 123
Query: 135 DFDWLRSKLEE--SQPTHLIPPLPEKFVVK------GVVDRFSEEFVETRRKALDKFLKR 186
DF L KL E SQ ++PP PEK ++ G D S EF+E RR AL+++L+R
Sbjct: 124 DFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQR 183
Query: 187 ITDHPVLSFNEHFNIFLTAKDL----NAYKKQGIALLTRMGESVKHVTG-GYKLRTRPLE 241
I +HP + + FL ++L G LL ++ V+ K+ +
Sbjct: 184 IVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW 243
Query: 242 FAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGV 301
F ++ +L + + + ++ E + ++ + + E A L
Sbjct: 244 FEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTA--LSRA 301
Query: 302 SACIGNCSTALEEL-TDDMTEDFL---PVLREYI--------LYSDSMKSVLKKRD---Q 346
+ + +E+L + DF +L +YI + MK+ + +D
Sbjct: 302 LSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQAT 361
Query: 347 VQAEYEAKLEAVALRKEDRPKVPAD--------VEKCQDRMECFNADLKADMERWQNNKR 398
+Q + EA+ + K D+ + D V + + E + ++ ++ R++ K
Sbjct: 362 LQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKS 421
Query: 399 QDFRQLLMGMADKNIQYYEKCLMAWESIIP 428
+DF+ ++ + + ++ WE+ +P
Sbjct: 422 KDFKNHVIKYLETLLYSQQQLAKYWEAFLP 451
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 73.9 bits (180), Expect = 3e-13
Identities = 86/355 (24%), Positives = 143/355 (40%), Gaps = 38/355 (10%)
Query: 95 VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152
+DDP K M++YI+Y++ T+V V RRY+ FDWL ++L E P +
Sbjct: 280 IDDPTKQTKFKGMKSYISYKLVPTHTQVP-------VHRRYKHFDWLYARLAEKFPVISV 332
Query: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYK 212
P LPE K RF E+F+ RRK L ++ + HPVL+ + F FLT K
Sbjct: 333 PHLPE----KQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEK 388
Query: 213 --KQGIALLTRMGESVKHVTGGY--KLRTRP---LEFAAIGDYLDTFALKLGTIDRIAQR 265
KQG R E + V + L T P L+ + +D F +D A +
Sbjct: 389 AWKQG----KRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQ 444
Query: 266 IIKEEIEYLVE-----LREYGPVYSTWSAL-------EGELAEPLEGVSACIGNCSTALE 313
+ E+ + +EY V ++ L + + L A G+ A+
Sbjct: 445 LNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIG 504
Query: 314 EL-TDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDRPKVPADV 372
EL + +D PV+ LY + + VQ K++ E+
Sbjct: 505 ELFAEQPRQDLDPVMDLLALYQGHLAN-FPDIIHVQKGALTKVKESRRHVEEGKMEVQKA 563
Query: 373 EKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESII 427
+ QDR + A++ + + +DF+ + + I +++K E +
Sbjct: 564 DGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEAL 618
>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
Length = 162
Score = 72.4 bits (176), Expect = 8e-13
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 7/141 (4%)
Query: 69 ASSSSLLNRLQ-LDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEY 127
A + L+ + Q L+D + L + V +P+ + TY I K+ F L E
Sbjct: 6 ADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKES 65
Query: 128 SVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDR-----FSEEFVETRRKALDK 182
+VRRRY DF+WLRS+LE ++PPLP K ++ + R F + F+E R++ L++
Sbjct: 66 TVRRRYSDFEWLRSELERESKV-VVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQ 124
Query: 183 FLKRITDHPVLSFNEHFNIFL 203
F+ ++ HP+ ++FL
Sbjct: 125 FINKVAGHPLAQNERCLHMFL 145
>gi|23397574 sorting nexin 33 [Homo sapiens]
Length = 574
Score = 71.6 bits (174), Expect = 1e-12
Identities = 75/347 (21%), Positives = 145/347 (41%), Gaps = 44/347 (12%)
Query: 95 VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152
V+DP K +++YI+Y++T V RRY+ FDWL ++L +
Sbjct: 234 VEDPTKQTKFKGIKSYISYKLTPTHAASP-------VYRRYKHFDWLYNRLLHKFTVISV 286
Query: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYK 212
P LPEK RF E+F+E R++ L ++ +T HPVLS E F FL+ D +K
Sbjct: 287 PHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWK 342
Query: 213 KQGIALLTRMGESVKHVTGG----YKLRTRPLEFAAIGDYLDTF----------ALKLGT 258
+ R E + V +++ T + + D +DTF L+L T
Sbjct: 343 -----MGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLST 397
Query: 259 IDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGEL-------AEPLEGVSACIGNCSTA 311
+A ++++ + +E+ + S + A+ +E L + G A
Sbjct: 398 ---VASELVRKHVGGF--RKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEA 452
Query: 312 LEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDRPKVPAD 371
+ E+ + ++ L + + + + S +Q AK++ ++ V +
Sbjct: 453 IGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDE 512
Query: 372 VEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEK 418
+ + R L+A+M + + DF+ ++ + I +Y++
Sbjct: 513 ADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQR 559
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 16/124 (12%)
Query: 95 VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152
+DDP K M++YI+Y++ T+V V RRY+ FDWL ++L E P +
Sbjct: 280 IDDPTKQTKFKGMKSYISYKLVPTHTQVP-------VHRRYKHFDWLYARLAEKFPVISV 332
Query: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLT---AKDLN 209
P LPE K RF E+F+ RRK L ++ + HPVL+ + F FLT + D
Sbjct: 333 PHLPE----KQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEK 388
Query: 210 AYKK 213
A+K+
Sbjct: 389 AWKQ 392
>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
Length = 628
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 16/124 (12%)
Query: 95 VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152
+DDP K M++YI+Y++ T+V V RRY+ FDWL ++L E P +
Sbjct: 280 IDDPTKQTKFKGMKSYISYKLVPTHTQVP-------VHRRYKHFDWLYARLAEKFPVISV 332
Query: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLT---AKDLN 209
P LPE K RF E+F+ RRK L ++ + HPVL+ + F FLT + D
Sbjct: 333 PHLPE----KQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEK 388
Query: 210 AYKK 213
A+K+
Sbjct: 389 AWKQ 392
>gi|23111030 sorting nexin 12 [Homo sapiens]
Length = 162
Score = 68.2 bits (165), Expect = 1e-11
Identities = 35/101 (34%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 108 YITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDR 167
+ TY + ++ F L E VRRRY DF+WL+++LE ++PPLP K + + + R
Sbjct: 47 FTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKI-VVPPLPGKALKRQLPFR 105
Query: 168 -----FSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFL 203
F E F+E RR+ L++F+ +I HP+ ++FL
Sbjct: 106 GDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFL 146
>gi|7706706 sorting nexin 9 [Homo sapiens]
Length = 595
Score = 66.6 bits (161), Expect = 4e-11
Identities = 82/357 (22%), Positives = 141/357 (39%), Gaps = 63/357 (17%)
Query: 94 IVDDPKK--HVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHL 151
+V DP+K + +++YI Y++T +T SV RY+ FDWL +L + +
Sbjct: 253 VVADPRKGSKMYGLKSYIEYQLTPTNTN-------RSVNHRYKHFDWLYERLLVKFGSAI 305
Query: 152 -IPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNA 210
IP LP+K V RF EEF++ R + L ++ R+ HPV+S +E F FL +D
Sbjct: 306 PIPSLPDK----QVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKE 361
Query: 211 YKKQGIALLTRMGESVKHVTGGYKLRTRPLEFAAIGDYLDTFALKLGTID-----RIAQR 265
+K TG K L I ++ A L ++ +
Sbjct: 362 WK-----------------TGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGK 404
Query: 266 IIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALE--------ELTD 317
K + + EL G + W G L + + + + + +T +L D
Sbjct: 405 FTKAMDDGVKELLTVGQEH--WKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLND 462
Query: 318 DMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKL-----------EAVALRKEDRP 366
+TE L ++ K L + EY+ L A+ KE
Sbjct: 463 AITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDK 522
Query: 367 KVPADVEKCQD------RMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYE 417
V QD R+ + L+A+M + +N+ D+ ++ ++ +Q+YE
Sbjct: 523 LVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYE 579
>gi|23111047 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 66.2 bits (160), Expect = 5e-11
Identities = 78/369 (21%), Positives = 153/369 (41%), Gaps = 57/369 (15%)
Query: 109 ITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTH--LIPPLPEKFVVKGVVD 166
+ + + TK+T F PE+SV R+++DF WL L E+ +IPP P K G +
Sbjct: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
Query: 167 RF-----------SEEFVETRRK--------------ALDKFLKRITDHPVLSFNEHFNI 201
+ EEF + +++ + + FL+R++ HPVLS + +F++
Sbjct: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
Query: 202 FLT-AKDLNAYKKQGIALLTRMGESVKHVTGG-YKLRTRPLE---FAAIGDYLDTFALK- 255
FL +DL+ +K + K + GG +K + + F + + D F +
Sbjct: 165 FLEYDQDLSVRRK-----------NTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEK 213
Query: 256 ---LGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTAL 312
+ +RI +K + T + L E + + +
Sbjct: 214 NFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELF 273
Query: 313 EEL-------TDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYE---AKLEAVALRK 362
E+L + D +LR Y+L ++ K +L +R + +YE L+ L+
Sbjct: 274 EKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKS 333
Query: 363 EDRPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMA 422
+D A ++C + E + K ++ ++ + FR+ L+ M++ I++ +
Sbjct: 334 KDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSL 393
Query: 423 WESIIPLLQ 431
+S I L +
Sbjct: 394 LQSCIDLFK 402
>gi|7657599 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 66.2 bits (160), Expect = 5e-11
Identities = 78/369 (21%), Positives = 153/369 (41%), Gaps = 57/369 (15%)
Query: 109 ITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTH--LIPPLPEKFVVKGVVD 166
+ + + TK+T F PE+SV R+++DF WL L E+ +IPP P K G +
Sbjct: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
Query: 167 RF-----------SEEFVETRRK--------------ALDKFLKRITDHPVLSFNEHFNI 201
+ EEF + +++ + + FL+R++ HPVLS + +F++
Sbjct: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
Query: 202 FLT-AKDLNAYKKQGIALLTRMGESVKHVTGG-YKLRTRPLE---FAAIGDYLDTFALK- 255
FL +DL+ +K + K + GG +K + + F + + D F +
Sbjct: 165 FLEYDQDLSVRRK-----------NTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEK 213
Query: 256 ---LGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTAL 312
+ +RI +K + T + L E + + +
Sbjct: 214 NFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELF 273
Query: 313 EEL-------TDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYE---AKLEAVALRK 362
E+L + D +LR Y+L ++ K +L +R + +YE L+ L+
Sbjct: 274 EKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKS 333
Query: 363 EDRPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMA 422
+D A ++C + E + K ++ ++ + FR+ L+ M++ I++ +
Sbjct: 334 KDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSL 393
Query: 423 WESIIPLLQ 431
+S I L +
Sbjct: 394 LQSCIDLFK 402
>gi|23111026 sorting nexin 11 [Homo sapiens]
Length = 270
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/115 (31%), Positives = 61/115 (53%), Gaps = 5/115 (4%)
Query: 93 VIVDDPK-KHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHL 151
V V DP+ ++ + +Y+ Y+I + F VRRRY++F WLR +L+ +
Sbjct: 19 VRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVP 78
Query: 152 IPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAK 206
+P LP K G S+EF+E RR+ L FL+++ VL + ++FL ++
Sbjct: 79 VPELPGKSTFFGT----SDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQ 129
>gi|23111028 sorting nexin 11 [Homo sapiens]
Length = 270
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/115 (31%), Positives = 61/115 (53%), Gaps = 5/115 (4%)
Query: 93 VIVDDPK-KHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHL 151
V V DP+ ++ + +Y+ Y+I + F VRRRY++F WLR +L+ +
Sbjct: 19 VRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVP 78
Query: 152 IPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAK 206
+P LP K G S+EF+E RR+ L FL+++ VL + ++FL ++
Sbjct: 79 VPELPGKSTFFGT----SDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQ 129
>gi|23943858 sorting nexin 8 [Homo sapiens]
Length = 465
Score = 57.0 bits (136), Expect = 3e-08
Identities = 70/284 (24%), Positives = 117/284 (41%), Gaps = 44/284 (15%)
Query: 128 SVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRI 187
SV RRY DF + L P ++P LP K ++ EF+E RR+AL +F+ +
Sbjct: 105 SVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGA-----DREFIEARRRALKRFVNLV 159
Query: 188 TDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTGGYKLRTRPLEF----- 242
HP+ S + +FL+ + K L + V KL TR +F
Sbjct: 160 ARHPLFSEDVVLKLFLSFSGSDVQNK-----LKESAQCVGDEFLNCKLATRAKDFLPADI 214
Query: 243 --------AAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYS------TWS 288
I + ++F +RIA R I + L+ +E + S +W+
Sbjct: 215 QAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWA 274
Query: 289 ALE----GELAEPLEGVSA----CIGNCSTALEELTDDMTED---FLPVLREY-ILYSDS 336
AL G L + L+G+S + ++ +D+ E FL +L+ Y L
Sbjct: 275 ALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERH 334
Query: 337 MKSVLKKRDQVQAEYE-AKLEAVALRKEDRPKVPADVEKCQDRM 379
K VL K + +Y K + ++ ++R P VE+ + R+
Sbjct: 335 EKGVLHKHQRALHKYSLMKRQMMSATAQNRE--PESVEQLESRI 376
>gi|23111023 sorting nexin 10 [Homo sapiens]
Length = 201
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/97 (29%), Positives = 54/97 (55%), Gaps = 3/97 (3%)
Query: 107 TYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVD 166
+YI Y I + + F + VRRRY++F WLR +L+ + +P LP K + + +
Sbjct: 28 SYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNN 87
Query: 167 RFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFL 203
R + V+ RR+ L+ FL+++ + +L + ++FL
Sbjct: 88 R---QHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFL 121
>gi|72534838 sorting nexin 6B [Homo sapiens]
Length = 403
Score = 53.1 bits (126), Expect = 5e-07
Identities = 82/351 (23%), Positives = 153/351 (43%), Gaps = 50/351 (14%)
Query: 109 ITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTH--LIPPLP---------E 157
+ + + TKS F E+SV R++++F WL E++ +IPP P E
Sbjct: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
Query: 158 KFVVKGVVDR--FSEEFVETRRK------ALDK--------FLKRITDHPVLSFNEHFNI 201
K G D EEF + +++ A+ K FL+R+ HP L + +F +
Sbjct: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
Query: 202 FLT-AKDLNAYKKQGIALLTRMGESVKHV--TGGYKLRTRPLEFAAIGDYLD---TFALK 255
FL +DL+ K LL G ++++ + L T + D+ + TF L+
Sbjct: 160 FLEYGQDLSVRGKNRKELL---GGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLE 216
Query: 256 LGTIDR----IAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTA 311
T R A R+++ + L + +Y P+ + S+L + L +
Sbjct: 217 YHTRIRDACLRADRVMRAH-KCLAD--DYIPISAALSSLGTQEVNQLRTSFLKLAELFER 273
Query: 312 LEELTDDMTED----FLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAV-ALRKEDRP 366
L +L + D +LR Y+ S + K +L +R + A+YE +A+ R +R
Sbjct: 274 LRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNRE 333
Query: 367 KVPADVEK--CQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQY 415
PA+ + C R E + K ++ +++ + FR+ L+ +A+ +++
Sbjct: 334 VRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKH 384
>gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
Length = 418
Score = 44.3 bits (103), Expect = 2e-04
Identities = 69/354 (19%), Positives = 144/354 (40%), Gaps = 42/354 (11%)
Query: 109 ITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQ--PTHLIPPLP---------E 157
+ + + TKS+ F E+SV R++++F WL E++ ++IPP P E
Sbjct: 58 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 117
Query: 158 KF--VVKGVVDRFSEEFVETRRK------ALDK--------FLKRITDHPVLSFNEHFNI 201
K + +G EEF + +++ A+ K FL R+ HP+L + +F++
Sbjct: 118 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV 177
Query: 202 FLT-AKDLNAYKKQGIALLTRMGES-VKHVTGGYKLRTRPLE--FAAIGDYLDTFALKLG 257
FL +DL+ K L ++ VK G + ++ F +L + ++
Sbjct: 178 FLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVK 237
Query: 258 TIDRIAQRIIKEEIEYLVELREYG-PVYSTWSALEGELAEPLEGVSACIGNCSTALEELT 316
+ R+ + + G +Y+ + ++ + VS ++
Sbjct: 238 DASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVS 297
Query: 317 DDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYE---AKLEAVALRKEDRPKVPADVE 373
D +L+ Y+ S + K +L +R + +YE L+ + +D + +
Sbjct: 298 ADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQ 357
Query: 374 KCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMAD-------KNIQYYEKCL 420
C + E + K ++ ++ + FR+ L+ +A+ N+Q + CL
Sbjct: 358 LCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCL 411
>gi|31543452 PX domain containing serine/threonine kinase [Homo
sapiens]
Length = 578
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 7/84 (8%)
Query: 127 YSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKR 186
+ + RRY DFD L + L Q L PLP K ++ G +DR EF+ R+K L +L
Sbjct: 50 WQIVRRYSDFDLLNNSL---QIAGLSLPLPPKKLI-GNMDR---EFIAERQKGLQNYLNV 102
Query: 187 ITDHPVLSFNEHFNIFLTAKDLNA 210
IT + +LS E FL + +A
Sbjct: 103 ITTNHILSNCELVKKFLDPNNYSA 126
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 127 YSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKR 186
+SV RRY +F L SKL E LP K ++ + EF++++R+ ++L++
Sbjct: 558 WSVYRRYLEFYVLESKLTEFHGAFPDAQLPSK----RIIGPKNYEFLKSKREEFQEYLQK 613
Query: 187 ITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTG 231
+ HP LS ++ FL+ I +G+ +K V G
Sbjct: 614 LLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPG 658
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 127 YSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKR 186
+SV RRY +F L SKL E LP K ++ + EF++++R+ ++L++
Sbjct: 611 WSVYRRYLEFYVLESKLTEFHGAFPDAQLPSK----RIIGPKNYEFLKSKREEFQEYLQK 666
Query: 187 ITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTG 231
+ HP LS ++ FL+ I +G+ +K V G
Sbjct: 667 LLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPG 711
>gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1
isoform a [Homo sapiens]
Length = 1066
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 16/126 (12%)
Query: 92 FVIVDDPKKHVCTMETYITYRITTK--STRVEFDLPEYSVRRRYQDFDWLRSKLEESQP- 148
F V +P++H Y Y++T + S R D+ E V +RY DF L +L +
Sbjct: 14 FYTVTEPQRHP---RGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKN 70
Query: 149 ----THLIPPLPEKFVVKGVV-DRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFL 203
+ L PP KG+V RF E +E RR+ + L+ + P L ++ F
Sbjct: 71 LFRHSELFPPF-----AKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDFF 125
Query: 204 TAKDLN 209
+N
Sbjct: 126 KGGIIN 131
>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
sapiens]
Length = 464
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 112 RITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEE 171
R T V E+ V RRY +FD L + L++ P + +P K + D F +
Sbjct: 30 RFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALK-IPAKRIFG---DNFDPD 85
Query: 172 FVETRRKALDKFLKRITDHPVLSFNEHFNIFL 203
F++ RR L++F++ + +P L + FL
Sbjct: 86 FIKQRRAGLNEFIQNLVRYPELYNHPDVRAFL 117
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 112 RITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEE 171
R T V E+ V RRY +FD L + L++ P + +P K + D F +
Sbjct: 30 RFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALK-IPAKRIFG---DNFDPD 85
Query: 172 FVETRRKALDKFLKRITDHPVLSFNEHFNIFL 203
F++ RR L++F++ + +P L + FL
Sbjct: 86 FIKQRRAGLNEFIQNLVRYPELYNHPDVRAFL 117
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 112 RITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEE 171
R T V E+ V RRY +FD L + L++ P + +P K + D F +
Sbjct: 30 RFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALK-IPAKRIFG---DNFDPD 85
Query: 172 FVETRRKALDKFLKRITDHPVLSFNEHFNIFL 203
F++ RR L++F++ + +P L + FL
Sbjct: 86 FIKQRRAGLNEFIQNLVRYPELYNHPDVRAFL 117
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,496,641
Number of Sequences: 37866
Number of extensions: 831727
Number of successful extensions: 3007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2889
Number of HSP's gapped (non-prelim): 151
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.