Guide to the Human Genome
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Search of human proteins with 153082755

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153082755 interferon-induced protein with tetratricopeptide
repeats 2 [Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153082755 interferon-induced protein with tetratricopeptide r...   960   0.0  
gi|31542980 interferon-induced protein with tetratricopeptide re...   488   e-138
gi|72534658 interferon-induced protein with tetratricopeptide re...   488   e-138
gi|6912630 interferon-induced protein with tetratricopeptide rep...   403   e-112
gi|116534937 interferon-induced protein with tetratricopeptide r...   397   e-111
gi|58330892 interferon-induced protein with tetratricopeptide re...   384   e-106
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               45   1e-04
gi|83415184 transmembrane and tetratricopeptide repeat containin...    42   0.001
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    38   0.017
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    38   0.017
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom...    38   0.017
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform...    38   0.017
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform...    37   0.030
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    37   0.039
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]               37   0.051
gi|38679914 mitochondrial distribution and morphology 20 [Homo s...    36   0.066
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     35   0.11 
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled...    35   0.15 
gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo sa...    35   0.19 
gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo sa...    35   0.19 
gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo sa...    35   0.19 
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]           35   0.19 
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]       34   0.25 
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]       34   0.25 
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    34   0.25 
gi|38201706 sterile alpha motif domain containing 9 [Homo sapiens]     34   0.25 
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi...    34   0.33 
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi...    34   0.33 
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo...    34   0.33 
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    33   0.43 

>gi|153082755 interferon-induced protein with tetratricopeptide
           repeats 2 [Homo sapiens]
          Length = 472

 Score =  960 bits (2481), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60
           MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL
Sbjct: 1   MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60

Query: 61  KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120
           KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV
Sbjct: 61  KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120

Query: 121 KHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAI 180
           KHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAI
Sbjct: 121 KHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAI 180

Query: 181 ASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEAL 240
           ASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEAL
Sbjct: 181 ASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEAL 240

Query: 241 EKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMN 300
           EKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMN
Sbjct: 241 EKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMN 300

Query: 301 LRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKE 360
           LRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKE
Sbjct: 301 LRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKE 360

Query: 361 FSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAK 420
           FSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAK
Sbjct: 361 FSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAK 420

Query: 421 MRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE 472
           MRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE
Sbjct: 421 MRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE 472


>gi|31542980 interferon-induced protein with tetratricopeptide
           repeats 3 [Homo sapiens]
          Length = 490

 Score =  488 bits (1255), Expect = e-138
 Identities = 270/472 (57%), Positives = 330/472 (69%), Gaps = 19/472 (4%)

Query: 1   MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60
           MSE  KNSLE  L QLKCHFTWNL + ++   D ED+V  + EF N EFKATM NLLAY+
Sbjct: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60

Query: 61  KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120
           KHL G NEAALECLR+AEELIQQEHADQAEIRSLVTWGNYAWVYYH+GRLSD QIYVDKV
Sbjct: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120

Query: 121 KHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAI 180
           K  C+KFS+PY IE  ELDCEEGWT+LKCG  +NERAKVCFEKALE+KP NPEF+SGLAI
Sbjct: 121 KQTCKKFSNPYSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAI 178

Query: 181 ASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEAL 240
           A Y LDN P  Q + D L+QAI L+PDNQY+KVLL LKL KM     +E EGE+ VEEAL
Sbjct: 179 AMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKM----NKEAEGEQFVEEAL 234

Query: 241 EKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMN 300
           EK+P  TDVLRSAAKFYRRK + DKAIEL ++ LE  PNN YL+ QIGCCY+AKV Q+ N
Sbjct: 235 EKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQN 294

Query: 301 LRENGMYGKRKLLE-LIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQK 359
             E+   G ++++E L  +A+ +  KA E   N     S LA       ++ + E Y Q 
Sbjct: 295 TGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLA-------EFLETECY-QT 346

Query: 360 EFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIA 419
            F+KE+    KQ  H RY N Q Y  K ED A+ H +EG+ I++KS +KE++KD+ Q ++
Sbjct: 347 PFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVS 406

Query: 420 KMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNG 471
           +  L +N  +   L  L  + + N  + QA +  E+  E G L+  A S  G
Sbjct: 407 ENLLPQNAPNYWYLQGL--IHKQNGDLLQAAKCYEK--ELGRLLRDAPSGIG 454


>gi|72534658 interferon-induced protein with tetratricopeptide
           repeats 3 [Homo sapiens]
          Length = 490

 Score =  488 bits (1255), Expect = e-138
 Identities = 270/472 (57%), Positives = 330/472 (69%), Gaps = 19/472 (4%)

Query: 1   MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60
           MSE  KNSLE  L QLKCHFTWNL + ++   D ED+V  + EF N EFKATM NLLAY+
Sbjct: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60

Query: 61  KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120
           KHL G NEAALECLR+AEELIQQEHADQAEIRSLVTWGNYAWVYYH+GRLSD QIYVDKV
Sbjct: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120

Query: 121 KHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAI 180
           K  C+KFS+PY IE  ELDCEEGWT+LKCG  +NERAKVCFEKALE+KP NPEF+SGLAI
Sbjct: 121 KQTCKKFSNPYSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAI 178

Query: 181 ASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEAL 240
           A Y LDN P  Q + D L+QAI L+PDNQY+KVLL LKL KM     +E EGE+ VEEAL
Sbjct: 179 AMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKM----NKEAEGEQFVEEAL 234

Query: 241 EKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMN 300
           EK+P  TDVLRSAAKFYRRK + DKAIEL ++ LE  PNN YL+ QIGCCY+AKV Q+ N
Sbjct: 235 EKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQN 294

Query: 301 LRENGMYGKRKLLE-LIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQK 359
             E+   G ++++E L  +A+ +  KA E   N     S LA       ++ + E Y Q 
Sbjct: 295 TGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLA-------EFLETECY-QT 346

Query: 360 EFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIA 419
            F+KE+    KQ  H RY N Q Y  K ED A+ H +EG+ I++KS +KE++KD+ Q ++
Sbjct: 347 PFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVS 406

Query: 420 KMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNG 471
           +  L +N  +   L  L  + + N  + QA +  E+  E G L+  A S  G
Sbjct: 407 ENLLPQNAPNYWYLQGL--IHKQNGDLLQAAKCYEK--ELGRLLRDAPSGIG 454


>gi|6912630 interferon-induced protein with tetratricopeptide
           repeats 5 [Homo sapiens]
          Length = 482

 Score =  403 bits (1035), Expect = e-112
 Identities = 215/464 (46%), Positives = 299/464 (64%), Gaps = 13/464 (2%)

Query: 1   MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60
           MSE  K++L++ L +L+CHFTWNL++ +  L + ED +  + EF   + +  + NLLAY+
Sbjct: 1   MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60

Query: 61  KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120
           KHLKGQN+ ALECL +AEE+IQQEH+D+ E+RSLVTWGNYAWVYYHM +L + Q Y  K+
Sbjct: 61  KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120

Query: 121 KHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGL 178
            +VC+K SSP  Y++E PE DCE+GW  LK GG   ++AK  FEKALE +P NPEF  G 
Sbjct: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180

Query: 179 AIASYRLDNWPPSQN----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEK 234
           AI  YRLD+     +    ++ PLR+A+ LNPDN Y+KV LALKL    ++   E EGEK
Sbjct: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKL----QDVHAEAEGEK 236

Query: 235 LVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294
            +EE L++      VLR AAKFYRRK+  +KA+ELLKKALE  P +++LH Q+G CYRA+
Sbjct: 237 YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ 296

Query: 295 VFQVMNLRENGMYGKRKLL--ELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYED 352
           + Q+     N   GK KL   ELI  A+ H K A E +       + LA+++A   QY +
Sbjct: 297 MIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSN 356

Query: 353 AEYYFQKEFSKE-LTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKM 411
           AE  F+K    E +T   K  +H  YG FQ +  K E+ AIHH++E +K+  +S  + K+
Sbjct: 357 AEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKL 416

Query: 412 KDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSER 455
              L+K++  RL  N  D ++L  L F+ +L  + +QA E  E+
Sbjct: 417 TSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460


>gi|116534937 interferon-induced protein with tetratricopeptide
           repeats 1 isoform 2 [Homo sapiens]
          Length = 478

 Score =  397 bits (1021), Expect = e-111
 Identities = 217/469 (46%), Positives = 304/469 (64%), Gaps = 17/469 (3%)

Query: 1   MSEN-NKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAY 59
           MS N + + ++ SL QL+CHFTW L   ++ + D E++V  + EF + ++   + NLLAY
Sbjct: 1   MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60

Query: 60  LKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDK 119
           +KHLKGQNE AL+ L++AE L+Q+EH +QA +RSLVTWGN+AW+YYHMGRL++ Q Y+DK
Sbjct: 61  VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120

Query: 120 VKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSG 177
           V+++C+K S+P  YR+E PE+DCEEGW  LKCGG   ERAK CFEK LE  P+NPE ++G
Sbjct: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180

Query: 178 LAIASYRLDNWPPSQN-----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEG 232
            AI++YRLD +  +       ++ PLRQA+RLNPDN Y+KVLLALKL   ++EG +E EG
Sbjct: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKL---QDEG-QEAEG 236

Query: 233 EKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYR 292
           EK +EEAL      T V R AAKFYRRK   DKA+ELLKKAL+  P +  LH QIG CY+
Sbjct: 237 EKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK 296

Query: 293 AKVFQVMNLRENGMYG--KRKLLELIGHAVAHLKKADEANDNLFRVCSI-LASLHALADQ 349
           A++ Q+    +    G  + KL ++I  A+ H + A E     F V  + LA ++  A  
Sbjct: 297 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPT-FEVAHLDLARMYIEAGN 355

Query: 350 YEDAEYYFQKEF-SKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREK 408
           +  AE  FQK    K +     Q +H  YG FQ +Q K +  AI H+++ +KI Q S  +
Sbjct: 356 HRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR 415

Query: 409 EKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGL 457
           +K  + L+K+   +L +   D E+L +L F+ +L   M +A E  ER L
Sbjct: 416 DKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL 464


>gi|58330892 interferon-induced protein with tetratricopeptide
           repeats 1-like [Homo sapiens]
          Length = 474

 Score =  384 bits (985), Expect = e-106
 Identities = 212/469 (45%), Positives = 297/469 (63%), Gaps = 17/469 (3%)

Query: 1   MSENNKNSL-ESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAY 59
           MSE +   L E SL QL+CHFTW L+     + D E++++   +F + ++   + NLLAY
Sbjct: 1   MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAY 60

Query: 60  LKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDK 119
           +KHLKGQNE AL  L+KAE+LIQ+EHA+QA+IRSLVTWGN+AWVYYHMGRL++ Q Y+DK
Sbjct: 61  VKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDK 120

Query: 120 VKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSG 177
           V++ C+KF++P  YR+E PE+DCEEGW   KCGG   ERAK CFEKALE  P+NPEF +G
Sbjct: 121 VENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTG 180

Query: 178 LAIASYRLDNWPPSQN-----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEG 232
            AI  YRLD +  +       ++  L++A+RLNPD+ Y++VLLALKL   ++EG +E EG
Sbjct: 181 YAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKL---QDEG-QEAEG 236

Query: 233 EKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYR 292
           EK +EEAL        V + AAKFYRRK   DKA+ELLK ALE  P +A+LH Q+G CYR
Sbjct: 237 EKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYR 296

Query: 293 AKVFQV---MNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQ 349
           A++ Q+    N +  G   +  +  L+  A+   +K              LA  +A    
Sbjct: 297 AQMIQIKEATNWQPRGQ-DRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGH 355

Query: 350 YEDAEYYFQKEF-SKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREK 408
           +  AE +FQK    K      KQ +H  YG FQ +  K +DKAI H+++G+KI + S  +
Sbjct: 356 HRKAEEHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSR 415

Query: 409 EKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGL 457
           EK+ + L+K+AK  + +N    E++ +L  + +L  ++  A    ER L
Sbjct: 416 EKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERAL 464


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 102/466 (21%), Positives = 190/466 (40%), Gaps = 64/466 (13%)

Query: 41   RTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNY 100
            + E +  +    + +L   L+ + G + A LE  +K E   Q+ H D  E        + 
Sbjct: 1143 KMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSA 1202

Query: 101  AWVYYHMGRLSDVQIYVD---KVKHVCEKFSSPYRIESPELDCE-EGWTRLKCGGNQNER 156
            +    H   L++++  V+   +VK   EK  S  ++E  +L    E  TR K      E+
Sbjct: 1203 SLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANA---EK 1259

Query: 157  AKVCFEKALEKKPKNPEFTSGLA--IASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVL 214
                +E+ L +     +  + LA  +A+ +   W  S   +  L +   L       K  
Sbjct: 1260 LCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSN 1319

Query: 215  LALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRS--------AAKFYRRKDEPDKA 266
               ++  +R + E+E + +  +  AL+KA    D+LR          A+ +R   + +  
Sbjct: 1320 FTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVN-- 1377

Query: 267  IELLKKALEYIPN---------NAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLEL-I 316
             E+++  ++Y  N         +A     I     A+   V N R   +   R  L+L +
Sbjct: 1378 AEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLEL 1437

Query: 317  GHAVAHLKKADEANDNLFRVCSILASLHALAD---QYEDAEYYFQKEFSKELTPVAKQLL 373
            G A++ L K   A   L +    L S  ALAD   ++E+++        KE+  ++ +LL
Sbjct: 1438 GDALSDLGKVRSAAARLDQ--KQLQSGKALADWKQKHEESQALLDAS-QKEVQALSTELL 1494

Query: 374  HLR--YGNFQLYQ--MKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKM-------- 421
             L+  Y    + Q  ++ E+K +   I    +  + RE  K   +++K+ K+        
Sbjct: 1495 KLKNTYEESIVGQETLRRENKNLQEEIS--NLTNQVREGTKNLTEMEKVKKLIEEEKTEV 1552

Query: 422  ---------RLSKNGADSEALH----VLAFLQELNEKMQQADEDSE 454
                      L +N  +S+ LH    +L    EL  K+ + DE+ E
Sbjct: 1553 QVTLEETEGALERN--ESKILHFQLELLEAKAELERKLSEKDEEIE 1596


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/220 (20%), Positives = 92/220 (41%), Gaps = 25/220 (11%)

Query: 153 QNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLK 212
           +N  A+  +++AL+   K  E  S L    Y    +   + A+   ++A  L P  + L+
Sbjct: 557 ENSMAEEWYKRALQVAHK-AEILSPLGALYYNTGRY---EEALQIYQEAAALQPSQRELR 612

Query: 213 VLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKK 272
           + LA  L  M +  E     EK+    + +  G  +  R  +  Y +++  DKA++ + K
Sbjct: 613 LALAQVLAVMGQTKE----AEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDK 668

Query: 273 ALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDN 332
           AL+  P +             KV   +   +     ++ LL+    A    + A + N +
Sbjct: 669 ALQLKPKD------------PKVISELFFTKGNQLREQNLLD---KAFESYRVAVQLNPD 713

Query: 333 LFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQL 372
             +    +  +  +  +Y  A  Y+++  + +L P +K L
Sbjct: 714 QAQAWMNMGGIQHIKGKYVSARAYYER--ALQLVPDSKLL 751



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 61/248 (24%), Positives = 107/248 (43%), Gaps = 44/248 (17%)

Query: 157 AKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQN----AIDPLRQAIRLNPDNQYLK 212
           AK+ +++AL+  P++         A + L N   SQ     AI  L+ +I+  P+     
Sbjct: 425 AKMYYQRALQLHPQHNR-------ALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAY 477

Query: 213 VLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKK 272
             LA  L     E E   E E++ +  ++  P  +D+  +   F      P+KA+   ++
Sbjct: 478 SSLASLL----AEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQ 533

Query: 273 ALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGM---YGKRKLLELIGHAVAHLKKADEA 329
           A++  P++      +G  YR       +L EN M   + KR L       VAH  KA+  
Sbjct: 534 AIKLSPSHHVAMVNLGRLYR-------SLGENSMAEEWYKRAL------QVAH--KAE-- 576

Query: 330 NDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQL-LHLRYGNFQLYQMKCE 388
                 + S L +L+    +YE+A   +Q+  +  L P  ++L L L      + Q K  
Sbjct: 577 ------ILSPLGALYYNTGRYEEALQIYQE--AAALQPSQRELRLALAQVLAVMGQTKEA 628

Query: 389 DKAIHHFI 396
           +K  +H +
Sbjct: 629 EKMTNHIV 636



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 47/185 (25%), Positives = 80/185 (43%), Gaps = 31/185 (16%)

Query: 27  GENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHA 86
           GENS+ +     +Y+   Q    KA + + L  L +  G+ E AL+  ++A  L      
Sbjct: 556 GENSMAE----EWYKRALQVAH-KAEILSPLGALYYNTGRYEEALQIYQEAAAL----QP 606

Query: 87  DQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEEGWTR 146
            Q E+R  +     A V   MG+  + +       H+  +       E+  L+C    + 
Sbjct: 607 SQRELRLAL-----AQVLAVMGQTKEAE---KMTNHIVSE-------ETGCLECYRLLSA 651

Query: 147 LKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAID----PLRQAI 202
           +      +++A    +KAL+ KPK+P+  S L    +   N    QN +D      R A+
Sbjct: 652 IYSKQENHDKALDAIDKALQLKPKDPKVISEL---FFTKGNQLREQNLLDKAFESYRVAV 708

Query: 203 RLNPD 207
           +LNPD
Sbjct: 709 QLNPD 713


>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 13/128 (10%)

Query: 194  AIDPLRQAIRLNPDNQYLKVLLALK--LHKMREEGEEEGEGEKLVEEALEKAPGVTDVLR 251
            A D   +A++ +P+N+Y+ +  A+   + K  EE +E+          +E  P    V  
Sbjct: 1495 ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKED------FANVIESCPFWAAVYF 1548

Query: 252  SAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRK 311
            + A FY    + + A E L KAL   PN+A ++      +RAKV   + L E  M    +
Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVY-----NFRAKVRGKIGLIEEAMADYNQ 1603

Query: 312  LLELIGHA 319
             L+L  +A
Sbjct: 1604 ALDLEDYA 1611


>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 13/128 (10%)

Query: 194  AIDPLRQAIRLNPDNQYLKVLLALK--LHKMREEGEEEGEGEKLVEEALEKAPGVTDVLR 251
            A D   +A++ +P+N+Y+ +  A+   + K  EE +E+          +E  P    V  
Sbjct: 1495 ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKED------FANVIESCPFWAAVYF 1548

Query: 252  SAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRK 311
            + A FY    + + A E L KAL   PN+A ++      +RAKV   + L E  M    +
Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVY-----NFRAKVRGKIGLIEEAMADYNQ 1603

Query: 312  LLELIGHA 319
             L+L  +A
Sbjct: 1604 ALDLEDYA 1611


>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
            sapiens]
          Length = 1614

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 13/128 (10%)

Query: 194  AIDPLRQAIRLNPDNQYLKVLLALK--LHKMREEGEEEGEGEKLVEEALEKAPGVTDVLR 251
            A D   +A++ +P+N+Y+ +  A+   + K  EE +E+          +E  P    V  
Sbjct: 1495 ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKED------FANVIESCPFWAAVYF 1548

Query: 252  SAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRK 311
            + A FY    + + A E L KAL   PN+A ++      +RAKV   + L E  M    +
Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVY-----NFRAKVRGKIGLIEEAMADYNQ 1603

Query: 312  LLELIGHA 319
             L+L  +A
Sbjct: 1604 ALDLEDYA 1611


>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
           [Homo sapiens]
          Length = 438

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 67/307 (21%), Positives = 116/307 (37%), Gaps = 52/307 (16%)

Query: 160 CFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKL 219
           C ++ALE  P    F    A     L  +P +Q+    + +    N D  Y++ L     
Sbjct: 108 CMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYY- 166

Query: 220 HKMREEGEEEGEGEKLVE---EALEKAPG---VTDVLRSAAKFYRRKDEPDKAI------ 267
                    E   EK V+   +AL  AP         R+A     +K++ +KA       
Sbjct: 167 ---------EDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYK 217

Query: 268 ---ELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLK 324
              EL  +AL   PNN   + ++ C               G    +  L  +  A+    
Sbjct: 218 LAYELYTEALGIDPNNIKTNAKLYC-------------NRGTVNSK--LRKLDDAIEDCT 262

Query: 325 KADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQ 384
            A + +D   +     A  +   +QYE+A   ++K +  E T   KQLL     N QL +
Sbjct: 263 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLK----NAQL-E 317

Query: 385 MKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNE 444
           +K   +  ++ I GV       +K   +D+++K  + R   +  D  +       +E  +
Sbjct: 318 LKKSKRKDYYKILGV-------DKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEK 370

Query: 445 KMQQADE 451
           K ++  E
Sbjct: 371 KFKEVGE 377


>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
           [Homo sapiens]
          Length = 494

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 66/307 (21%), Positives = 116/307 (37%), Gaps = 52/307 (16%)

Query: 160 CFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKL 219
           C ++ALE  P    F    A     L  +P +Q+    + +    N D  Y++ L     
Sbjct: 164 CMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYY- 222

Query: 220 HKMREEGEEEGEGEKLVE---EALEKAPG---VTDVLRSAAKFYRRKDEPDKAI------ 267
                    E   EK V+   +AL  AP         R+A     +K++ +KA       
Sbjct: 223 ---------EDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYK 273

Query: 268 ---ELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLK 324
              EL  +AL   PNN   + ++ C               G    +  L  +  A+    
Sbjct: 274 LAYELYTEALGIDPNNIKTNAKLYC-------------NRGTVNSK--LRKLDDAIEDCT 318

Query: 325 KADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQ 384
            A + +D   +     A  +   +QYE+A   ++K +  E T   KQL  L+    +L +
Sbjct: 319 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQL--LKNAQLELRK 376

Query: 385 MKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNE 444
            K +D   ++ I GV       +K   +D+++K  + R   +  D  +       +E  +
Sbjct: 377 SKRKD---YYKILGV-------DKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEK 426

Query: 445 KMQQADE 451
           K ++  E
Sbjct: 427 KFKEVGE 433


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 79/390 (20%), Positives = 155/390 (39%), Gaps = 61/390 (15%)

Query: 106  HMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKAL 165
            H   L D+Q+  DKV  + +   +  ++E    D E         G+  +  K+C +  L
Sbjct: 1007 HQQTLDDLQMEEDKVNTLTK---AKTKLEQQVDDLE---------GSLEQEKKLCMD--L 1052

Query: 166  EKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQA-IRLN------PDNQYLKVLLALK 218
            E+  +  E    LA  S  +D     Q   + L++    ++       D Q L + L  K
Sbjct: 1053 ERAKRKLEGDLKLAQES-TMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKK 1111

Query: 219  LHKMR---EEGEEEGEGEKL------------------VEEALEKAPGVTDVL-----RS 252
            + +++   EE EEE E E+                   + E LE+A G T        + 
Sbjct: 1112 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR 1171

Query: 253  AAKFYR-RKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRK 311
             A+F + R+D  +  ++    A      +A    ++G     ++  +  +++     K +
Sbjct: 1172 EAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELG----EQIDSLQRVKQKLEKEKSE 1227

Query: 312  LLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQ 371
            L   I    ++++   +A  N  ++C  L    +     E+ +     E S +     K 
Sbjct: 1228 LKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQ-----KA 1282

Query: 372  LLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSE 431
             LH   G F   Q+  +D  +     G +    +++ E++K +L++  K + +   A   
Sbjct: 1283 RLHTESGEFSR-QLDEKDAMVSQLSRGKQAF--TQQIEELKRQLEEETKAKSTLAHALQS 1339

Query: 432  ALHVLAFLQELNEKMQQADEDSERGLESGS 461
            A H    L+E  E+ Q+A  + +RG+   +
Sbjct: 1340 ARHDCDLLREQYEEEQEAKAELQRGMSKAN 1369


>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
          Length = 1012

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 52/256 (20%), Positives = 106/256 (41%), Gaps = 30/256 (11%)

Query: 215 LALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRK-----DEPDKAIEL 269
           L +KL++ + E EE+   E   +    K   +  +   A K Y ++     ++ +KA + 
Sbjct: 196 LEIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQA 255

Query: 270 LKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLL----ELIGHAVAHLKK 325
             +AL     +             ++ +   +    +Y +R+LL    +L+    A LK+
Sbjct: 256 KSEALVLREKSTL----------ERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQ 305

Query: 326 ADEA---NDNLF--RVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLH---LRY 377
             EA   N  L   +  SI  +L       +  E  + ++   EL     +L     +R 
Sbjct: 306 RVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKDDYIIRT 365

Query: 378 GNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLA 437
                 + K ++KA+H   E + IN K   KE++   + ++ ++ L      +++L +  
Sbjct: 366 NRLIEDERKNKEKAVHLQEELIAINSK---KEELNQSVNRVKELELELESVKAQSLAITK 422

Query: 438 FLQELNEKMQQADEDS 453
               LNEK+++  + S
Sbjct: 423 QNHMLNEKVKEMSDYS 438


>gi|38679914 mitochondrial distribution and morphology 20 [Homo
           sapiens]
          Length = 972

 Score = 36.2 bits (82), Expect = 0.066
 Identities = 26/109 (23%), Positives = 52/109 (47%), Gaps = 2/109 (1%)

Query: 198 LRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFY 257
           ++QA +L   ++ L     LK   ++  G++E E   L +E     P   + L++    Y
Sbjct: 31  IQQADKLLKKHKDLHCAKVLKAIGLQRTGKQE-EAFTLAQEVAALEPTDDNSLQALTILY 89

Query: 258 RRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGM 306
           R    P+   +L + A++ +PN+   H  +   Y A+V +   +++ GM
Sbjct: 90  REMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAY-ARVGEYKKMQQAGM 137


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 22/81 (27%), Positives = 47/81 (58%), Gaps = 3/81 (3%)

Query: 381  QLYQMKCEDKAIHHFIEGVKINQKSREKE--KMKDKLQKIAKMRLSKNGADSEALHVLAF 438
            Q+Y MK E +     +E V ++ KS+E+E   ++D+L+  +  +L++    +E   + A 
Sbjct: 1593 QVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ-KIAAI 1651

Query: 439  LQELNEKMQQADEDSERGLES 459
             ++L  +M++ +E  ++G ES
Sbjct: 1652 KKQLLSQMEEKEEQYKKGTES 1672


>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 2 [Homo sapiens]
          Length = 1990

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 22/70 (31%), Positives = 35/70 (50%)

Query: 211  LKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELL 270
            LKV L L L + R +  + G  E+   +ALE  P   +   + A+  R   +   A+E L
Sbjct: 1289 LKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDL 1348

Query: 271  KKALEYIPNN 280
             +A++  PNN
Sbjct: 1349 NEAIKLCPNN 1358


>gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo
           sapiens]
          Length = 515

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 20/129 (15%)

Query: 231 EGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCC 290
           E EK  + AL K   + D     AK Y   D+P  A+ L K+ L+  P    L C I   
Sbjct: 243 EAEKQFKSAL-KQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGI--- 298

Query: 291 YRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQY 350
             A++++ MN               +  A  + K+  + ++      + + S H  +DQ 
Sbjct: 299 --ARIYEEMN--------------NMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQP 342

Query: 351 EDAEYYFQK 359
           E A  ++++
Sbjct: 343 EIALRFYRR 351


>gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo
           sapiens]
          Length = 475

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 20/129 (15%)

Query: 231 EGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCC 290
           E EK  + AL K   + D     AK Y   D+P  A+ L K+ L+  P    L C I   
Sbjct: 203 EAEKQFKSAL-KQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGI--- 258

Query: 291 YRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQY 350
             A++++ MN               +  A  + K+  + ++      + + S H  +DQ 
Sbjct: 259 --ARIYEEMN--------------NMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQP 302

Query: 351 EDAEYYFQK 359
           E A  ++++
Sbjct: 303 EIALRFYRR 311


>gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo
           sapiens]
          Length = 505

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 20/129 (15%)

Query: 231 EGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCC 290
           E EK  + AL K   + D     AK Y   D+P  A+ L K+ L+  P    L C I   
Sbjct: 233 EAEKQFKSAL-KQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGI--- 288

Query: 291 YRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQY 350
             A++++ MN               +  A  + K+  + ++      + + S H  +DQ 
Sbjct: 289 --ARIYEEMN--------------NMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQP 332

Query: 351 EDAEYYFQK 359
           E A  ++++
Sbjct: 333 EIALRFYRR 341


>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
          Length = 1564

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 5/113 (4%)

Query: 179 AIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEE 238
           A A  +L ++  S+ AI  L Q      D   +  LL LK    R +G  + E  K++E+
Sbjct: 357 AEALIKLSDYDSSEEAIRTLDQI----SDADNIPGLLVLKSLAYRNKGSFD-EAAKIMED 411

Query: 239 ALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCY 291
            L   P + +V    A  +  K +  +A +  ++ALE     A  H Q+G  Y
Sbjct: 412 LLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTY 464


>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
          Length = 1036

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 192 QNAIDPLRQAIRLNPD--NQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDV 249
           Q AI+  R A+RL PD  + Y+ +  AL        G+ EG  +  V  AL+  P +  V
Sbjct: 96  QEAIEHYRHALRLKPDFIDGYINLAAALV-----AAGDMEGAVQAYV-SALQYNPDLYCV 149

Query: 250 LRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294
                   +     ++A     KA+E  PN A     +GC + A+
Sbjct: 150 RSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 194



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 45/185 (24%), Positives = 72/185 (38%), Gaps = 24/185 (12%)

Query: 23  NLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQ 82
           N ++ + S+ + ED   Y T  +     A   N LA +K  +G  E A+   RKA E+  
Sbjct: 291 NALKEKGSVAEAED--CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP 348

Query: 83  QEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEE 142
           +  A  +         N A V    G+L +  ++  +   +   F+  Y           
Sbjct: 349 EFAAAHS---------NLASVLQQQGKLQEALMHYKEAIRISPTFADAY--------SNM 391

Query: 143 GWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAI 202
           G T  +    Q   A  C+ +A++  P   +  S LA       N P    AI   R A+
Sbjct: 392 GNTLKEMQDVQG--ALQCYTRAIQINPAFADAHSNLASIHKDSGNIP---EAIASYRTAL 446

Query: 203 RLNPD 207
           +L PD
Sbjct: 447 KLKPD 451


>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
          Length = 1046

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 192 QNAIDPLRQAIRLNPD--NQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDV 249
           Q AI+  R A+RL PD  + Y+ +  AL        G+ EG  +  V  AL+  P +  V
Sbjct: 106 QEAIEHYRHALRLKPDFIDGYINLAAALV-----AAGDMEGAVQAYV-SALQYNPDLYCV 159

Query: 250 LRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294
                   +     ++A     KA+E  PN A     +GC + A+
Sbjct: 160 RSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 204



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 45/185 (24%), Positives = 72/185 (38%), Gaps = 24/185 (12%)

Query: 23  NLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQ 82
           N ++ + S+ + ED   Y T  +     A   N LA +K  +G  E A+   RKA E+  
Sbjct: 301 NALKEKGSVAEAED--CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP 358

Query: 83  QEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEE 142
           +  A  +         N A V    G+L +  ++  +   +   F+  Y           
Sbjct: 359 EFAAAHS---------NLASVLQQQGKLQEALMHYKEAIRISPTFADAY--------SNM 401

Query: 143 GWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAI 202
           G T  +    Q   A  C+ +A++  P   +  S LA       N P    AI   R A+
Sbjct: 402 GNTLKEMQDVQG--ALQCYTRAIQINPAFADAHSNLASIHKDSGNIP---EAIASYRTAL 456

Query: 203 RLNPD 207
           +L PD
Sbjct: 457 KLKPD 461


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 69/349 (19%), Positives = 122/349 (34%), Gaps = 32/349 (9%)

Query: 116 YVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFT 175
           ++ K+K V         IES  L  E    R+  G N+ E A V FEK ++ K    E  
Sbjct: 149 FISKIKSVSASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHI 208

Query: 176 SGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKL 235
                                 +++ I+ N  +Q L V +  +   +REE ++  E EK 
Sbjct: 209 ----------------------IKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQ 246

Query: 236 VEEALEKAPGVTDVLRSAAKFYR----RKDEPDK-AIELLKKALEYIPNNAYLHCQIGCC 290
               +++     + L    K  R     +D   K A++ L K +      A   C+    
Sbjct: 247 HMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQ 306

Query: 291 YRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCS-ILASLHALADQ 349
            +  +       E      RK  E +   +    K  E N N  +  S     LH L + 
Sbjct: 307 EKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYET 366

Query: 350 YEDAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIE--GVKINQKSRE 407
            E       +E  K    +   ++ +++   +L       K     ++    K+ Q   E
Sbjct: 367 KEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEE 426

Query: 408 KEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQ--ELNEKMQQADEDSE 454
            ++++   Q + K         S  L     +   EL ++MQ+  +  E
Sbjct: 427 ADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLE 475


>gi|38201706 sterile alpha motif domain containing 9 [Homo sapiens]
          Length = 1589

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 11/120 (9%)

Query: 219  LHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIP 278
            LHK  +EG E  E   L+E      P        A  FY +K +   A+   K+A    P
Sbjct: 1058 LHK--DEGNEAVEAV-LLESIHRFNPNAFICQALARHFYIKKKDFGNALNWAKQAKIIEP 1114

Query: 279  NNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRK------LLELIGHAVAHLKKADEANDN 332
            +N+Y+   +G  Y++K+     + ENG  G         LL+L  HA +  K++ + +++
Sbjct: 1115 DNSYISDTLGQVYKSKI--RWWIEENGGNGNISVDDLIALLDLAEHASSAFKESQQQSED 1172


>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
           sapiens]
          Length = 830

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 44/203 (21%), Positives = 83/203 (40%), Gaps = 12/203 (5%)

Query: 81  IQQEHADQAEI--RSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPEL 138
           +Q+EH    +   R++    NYA+ Y  +G    +   +DK    C  F +  R+     
Sbjct: 585 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL-AC--FRNAIRVNPRHY 641

Query: 139 DCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPL 198
           +   G   +     +   A++ F+KAL+  P++      + +  + L     S+ A+D L
Sbjct: 642 NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK---SEKALDTL 698

Query: 199 RQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYR 258
            +AI ++P N   K   A  L       E+     + +EE  +  P  + V     K Y+
Sbjct: 699 NKAIVIDPKNPLCKFHRASVLF----ANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 754

Query: 259 RKDEPDKAIELLKKALEYIPNNA 281
           +  +   A+     A++  P  A
Sbjct: 755 KLGQTHLALMNFSWAMDLDPKGA 777


>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
           sapiens]
          Length = 824

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 44/203 (21%), Positives = 83/203 (40%), Gaps = 12/203 (5%)

Query: 81  IQQEHADQAEI--RSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPEL 138
           +Q+EH    +   R++    NYA+ Y  +G    +   +DK    C  F +  R+     
Sbjct: 579 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL-AC--FRNAIRVNPRHY 635

Query: 139 DCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPL 198
           +   G   +     +   A++ F+KAL+  P++      + +  + L     S+ A+D L
Sbjct: 636 NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK---SEKALDTL 692

Query: 199 RQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYR 258
            +AI ++P N   K   A  L       E+     + +EE  +  P  + V     K Y+
Sbjct: 693 NKAIVIDPKNPLCKFHRASVLF----ANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748

Query: 259 RKDEPDKAIELLKKALEYIPNNA 281
           +  +   A+     A++  P  A
Sbjct: 749 KLGQTHLALMNFSWAMDLDPKGA 771


>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
           sapiens]
          Length = 805

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 31/121 (25%), Positives = 59/121 (48%), Gaps = 14/121 (11%)

Query: 351 EDAEYYFQKEFSKELTPVAKQLLHL------RYGNFQLYQMKCEDK--AIHHFIEGVKI- 401
           E   +  Q EF ++L    K++L L      R   F   + K E+K      +I  +K  
Sbjct: 434 ESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKK 493

Query: 402 ----NQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGL 457
               +++++EK++  + L+K      + +   S++L  L  L+E N+ +Q+A  D+E+ L
Sbjct: 494 CQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQ-LQILEEKNKNLQEALIDTEKKL 552

Query: 458 E 458
           E
Sbjct: 553 E 553


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 12/144 (8%)

Query: 318 HAVAHLKKADEANDNLFRVCS-------ILASLHALADQYEDAEYYFQKEFSKELTPVAK 370
           HAV  L+   EA D + R+         +  +L A+A Q + A+ Y + E +KE   ++ 
Sbjct: 151 HAVKQLE--GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIE-ELTKERDALSL 207

Query: 371 QLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADS 430
           +L      + +L +   + +     +E  K   +   KE +K KL++ AK+ L +    +
Sbjct: 208 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE-LKRKLER-AKLLLPQQQLQA 265

Query: 431 EALHVLAFLQELNEKMQQADEDSE 454
           EA H+   LQ ++ K+Q   E++E
Sbjct: 266 EADHLGKELQSVSAKLQAQVEENE 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,814,882
Number of Sequences: 37866
Number of extensions: 798847
Number of successful extensions: 3567
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 3411
Number of HSP's gapped (non-prelim): 192
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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