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Search of human proteins with 150456436
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo
sapiens]
(1173 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens] 2347 0.0
gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens] 2321 0.0
gi|169790964 hypothetical protein LOC51252 isoform A [Homo sapiens] 215 2e-55
gi|31745176 hypothetical protein LOC51252 isoform B [Homo sapiens] 62 2e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 55 3e-07
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 55 4e-07
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 52 3e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 52 3e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 52 3e-06
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 51 6e-06
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 51 7e-06
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 51 7e-06
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 50 1e-05
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 50 1e-05
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 50 1e-05
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 50 1e-05
gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 49 4e-05
gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 49 4e-05
gi|125656165 THO complex 2 [Homo sapiens] 48 6e-05
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 48 6e-05
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 47 8e-05
gi|87299628 biorientation of chromosomes in cell division 1-like... 47 1e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 1e-04
gi|161016767 mucin 21 [Homo sapiens] 47 1e-04
gi|217330641 IWS1 homolog [Homo sapiens] 46 2e-04
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 46 2e-04
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 46 2e-04
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 45 3e-04
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 45 3e-04
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 45 3e-04
>gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]
Length = 1173
Score = 2347 bits (6083), Expect = 0.0
Identities = 1173/1173 (100%), Positives = 1173/1173 (100%)
Query: 1 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK 60
MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK
Sbjct: 1 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK 60
Query: 61 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK 120
QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK
Sbjct: 61 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK 120
Query: 121 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH 180
EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH
Sbjct: 121 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH 180
Query: 181 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL 240
ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL
Sbjct: 181 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL 240
Query: 241 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 300
ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN
Sbjct: 241 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 300
Query: 301 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF 360
NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF
Sbjct: 301 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF 360
Query: 361 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST 420
LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST
Sbjct: 361 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST 420
Query: 421 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP 480
RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP
Sbjct: 421 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP 480
Query: 481 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI 540
SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI
Sbjct: 481 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI 540
Query: 541 SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD 600
SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD
Sbjct: 541 SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD 600
Query: 601 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV 660
FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV
Sbjct: 601 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV 660
Query: 661 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE 720
HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE
Sbjct: 661 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE 720
Query: 721 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG 780
HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG
Sbjct: 721 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG 780
Query: 781 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF 840
KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF
Sbjct: 781 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF 840
Query: 841 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS 900
SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS
Sbjct: 841 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS 900
Query: 901 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD 960
SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD
Sbjct: 901 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD 960
Query: 961 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV 1020
FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV
Sbjct: 961 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV 1020
Query: 1021 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE 1080
IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE
Sbjct: 1021 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE 1080
Query: 1081 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV 1140
LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV
Sbjct: 1081 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV 1140
Query: 1141 KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS 1173
KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS
Sbjct: 1141 KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS 1173
>gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]
Length = 1186
Score = 2321 bits (6016), Expect = 0.0
Identities = 1162/1162 (100%), Positives = 1162/1162 (100%)
Query: 1 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK 60
MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK
Sbjct: 1 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK 60
Query: 61 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK 120
QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK
Sbjct: 61 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK 120
Query: 121 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH 180
EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH
Sbjct: 121 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH 180
Query: 181 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL 240
ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL
Sbjct: 181 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL 240
Query: 241 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 300
ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN
Sbjct: 241 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 300
Query: 301 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF 360
NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF
Sbjct: 301 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF 360
Query: 361 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST 420
LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST
Sbjct: 361 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST 420
Query: 421 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP 480
RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP
Sbjct: 421 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP 480
Query: 481 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI 540
SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI
Sbjct: 481 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI 540
Query: 541 SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD 600
SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD
Sbjct: 541 SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD 600
Query: 601 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV 660
FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV
Sbjct: 601 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV 660
Query: 661 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE 720
HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE
Sbjct: 661 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE 720
Query: 721 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG 780
HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG
Sbjct: 721 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG 780
Query: 781 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF 840
KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF
Sbjct: 781 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF 840
Query: 841 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS 900
SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS
Sbjct: 841 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS 900
Query: 901 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD 960
SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD
Sbjct: 901 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD 960
Query: 961 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV 1020
FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV
Sbjct: 961 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV 1020
Query: 1021 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE 1080
IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE
Sbjct: 1021 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE 1080
Query: 1081 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV 1140
LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV
Sbjct: 1081 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV 1140
Query: 1141 KDLVARIHGKWQEIIQNCRPTQ 1162
KDLVARIHGKWQEIIQNCRPTQ
Sbjct: 1141 KDLVARIHGKWQEIIQNCRPTQ 1162
>gi|169790964 hypothetical protein LOC51252 isoform A [Homo sapiens]
Length = 647
Score = 215 bits (547), Expect = 2e-55
Identities = 157/511 (30%), Positives = 249/511 (48%), Gaps = 33/511 (6%)
Query: 663 GTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEEHK 722
G+Y N L+ L L E ++Q E R+ ++ + + D ++E L EH+
Sbjct: 163 GSYFNNLDYL---------LQEKREQALEQERERLLLQECLNLNSLDLDEEEVPLTPEHR 213
Query: 723 EFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLD-LRDSGFIG-QSAVEKLILKSG 780
++K+SV++ IP HPGE +F + + L + DS + +S +E L L S
Sbjct: 214 MLVEKYSVSLQTIPPVHPGETVF-------LPRCHPLPCILDSSLLKPRSHLEGLFLSSP 266
Query: 781 KTDQIFLTTQGFLTSAY-HYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDT 839
Q+ G L Y H CPV +L+WLF++++ + S+ L ++ +
Sbjct: 267 PAQQLSFLRSGLLNILYLHMPDCPVSLLQWLFQLLTWPPE--TSLGAFGLLWDLIVDGIF 324
Query: 840 FS-DSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESE 898
D W PSL +V F ++G +L+PL F V + E +
Sbjct: 325 LQPDEDKHLWCPSLQEVREAFHSLGAHSPALYPLG----PFWHGGRVLPGEAGLNENEEQ 380
Query: 899 DSSYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPL 958
D+ + + ++ ++ KFL LC P Y D +M LI +L + SL+ L+ +P
Sbjct: 381 DAPQEIAL----DISLGHIYKFLALCAQAQPGAYTDENLMGLIELLCRTSLDVGLRLLPK 436
Query: 959 VDFQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLS 1018
VD Q LL+ L++NIR+W K+ ELC ++ +S H HNLL LVQ P+ TSR R+LR LS
Sbjct: 437 VDLQQLLLLLLENIREWPGKLQELCCTLSWVSDHHHNLLALVQFFPDMTSRSRRLRSQLS 496
Query: 1019 LVIISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLH 1078
LV+I+++L ++ Q+S L R L M+PS L + L P
Sbjct: 497 LVVIARMLGQQEMLPLWQEKTQLSSLSRLLGLMRPSSL--RQYLDSVPLPPCQEQQPKAS 554
Query: 1079 LELEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRT 1138
EL+ +A YL + LL L G V + Q LLC L++H+ IRE + +RT
Sbjct: 555 AELDHKACYLCHSLLMLAGVVVSCQDITPDQWGELQLLCMQLDRHISTQIRESPQAMHRT 614
Query: 1139 KVKDLVARIHGKWQEIIQNCRPTQGQLHDFW 1169
+KDL + + +WQE++ +C+P Q Q W
Sbjct: 615 MLKDLATQTYIRWQELLTHCQP-QAQYFSPW 644
>gi|31745176 hypothetical protein LOC51252 isoform B [Homo sapiens]
Length = 119
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 1080 ELEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTK 1139
EL+ +A YL + LL L G V + Q LLC L++H+ IRE + +RT
Sbjct: 28 ELDHKACYLCHSLLMLAGVVVSCQDITPDQWGELQLLCMQLDRHISTQIRESPQAMHRTM 87
Query: 1140 VKDLVARIHGKWQEIIQNCRPTQGQLHDFW 1169
+KDL + + +WQE++ +C+P Q Q W
Sbjct: 88 LKDLATQTYIRWQELLTHCQP-QAQYFSPW 116
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 55.5 bits (132), Expect = 3e-07
Identities = 89/480 (18%), Positives = 180/480 (37%), Gaps = 50/480 (10%)
Query: 180 HENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLS 239
+++N+K+D +GK+++ +++D ++S+ S SS SS S S + S
Sbjct: 534 NDDNDKSDSGKGKSDS--------SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585
Query: 240 LASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGK 299
+S + + + +S++S S SS S SS ++D +
Sbjct: 586 DSSDSSD-------SDSSDSSNSSDSSDSSDSSDSSDSS--------DSSDSKSDSSKSE 630
Query: 300 NNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARES 359
++ S+ ++ S +SSDS + + + N +S DS S S + S
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS---SNSSDSSDSSDSSDSSSSSDSSNSS 687
Query: 360 FLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHS 419
D + E S + SD +D S+ + S++ NS
Sbjct: 688 DSSDSSDSSNSSE--------------------SSDSSDSSDSDSSDSSDSSNSNSSDSD 727
Query: 420 TRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRV 479
+ NS + S + S +SN + +S ++ ++ S
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 480 PSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSS-- 537
S S + + + S SS S +S++S+ + +N +DS+ SS
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 538 --GKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKR 595
G S RS+ + S ++ S ++ S+++ + +SS +SN+ S
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907
Query: 596 KLRGDFDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSD 655
SD + + +S + S + + + + + ++ + + S SSD
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967
Score = 51.6 bits (122), Expect = 4e-06
Identities = 85/474 (17%), Positives = 170/474 (35%), Gaps = 48/474 (10%)
Query: 182 NNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLA 241
+++ +D ++DS + +++D N S S SS SS S S + +
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 242 SYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNN 301
S NS +S ++S SS + +D N+
Sbjct: 889 S-------------------NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 302 LSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFL 361
N + S SSDS + +++ N +S DS+ + +S + S
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS----SNSSDS 985
Query: 362 EKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTR 421
D + D D S + SD +D S++ + ++S +S +
Sbjct: 986 SDSSDSSDSSDS----------SDSSNSSD-SSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034
Query: 422 NSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPS 481
+S + S + S +S+ + +S ++ E+ S
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS-------DS 1087
Query: 482 AGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKIS 541
+ SS N+ + + D SS S S++S+ + ++ +DS+ SS S
Sbjct: 1088 SDSS----NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-S 1142
Query: 542 GGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGDF 601
SE + S ++ S ++ S + + +SS +S++ S+
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 602 DSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSD 655
DS + S + DS + ++ S + + + N++ ++ + S SSD
Sbjct: 1203 DSSDSS--DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254
Score = 50.8 bits (120), Expect = 7e-06
Identities = 69/394 (17%), Positives = 148/394 (37%), Gaps = 8/394 (2%)
Query: 263 SENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEP 322
+E+ S+++S + S + ++D GK++ S+ ++ S SSDS +
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569
Query: 323 TSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKT 382
S+ S + + +S DS + +S + K + K+
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629
Query: 383 PGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLP 442
D S SD +D +S+ + ++ + +S+ +SD + + ++
Sbjct: 630 ESD----SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS-S 684
Query: 443 LSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKD 502
S + S +SN ++ +S ++ + S S+ S N+ + + + D
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD--SSNSSDSSDSSNSSD 742
Query: 503 KERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEV 562
SS S S++S+ ++ +DS+ SS + + S +
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Query: 563 VPCIPSPAAPSDKAPSE-GESSGNSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETL 621
+ SD + S+ SS +SN+ S+ DS + S G + DS ++
Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS 862
Query: 622 KSLEEIMALNFNQTPAATGKPPALSKGLRSQSSD 655
S + + + + + ++ + S SSD
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896
Score = 37.4 bits (85), Expect = 0.085
Identities = 46/245 (18%), Positives = 89/245 (36%), Gaps = 11/245 (4%)
Query: 181 ENNEKNDRDRGKTNADSKKQTTVAEA-DIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLS 239
++++ +D ++DS + +E+ D ++S+ S SS SS S + S S
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 240 LASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGK 299
+S + + + +S++S S SS S SS + +D
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 300 NNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARES 359
N+ + ++ S SSDS + + + + +S DS S + S
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 360 FLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHS 419
D + + D D + + +DE+D S +N+G+
Sbjct: 1239 DSSDSSDSSNSSDS----------SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288
Query: 420 TRNSD 424
+ SD
Sbjct: 1289 SEGSD 1293
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 55.1 bits (131), Expect = 4e-07
Identities = 74/325 (22%), Positives = 127/325 (39%), Gaps = 23/325 (7%)
Query: 167 KHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHH 226
+ RS R +S H ++ R ++ SK ++ + SRS S S S+
Sbjct: 187 RSRSHSRSRSRSRHSRKSRS-RSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 227 PEESPLGAKFQLSLASYCRERELKRLRKEQMEQRI-NSEN-----SFSEASSLSLKSSIE 280
SP K + S + R K+Q E++I N++N S S + S S
Sbjct: 246 KSRSPSKEKSRSRSHSAGKSRSKS---KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRS 302
Query: 281 RKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNS 340
R + R E+ K+ + G++ ++ SR RS S + + SK + RKR+
Sbjct: 303 RSQERRVEEEKRGSVSRGRSQEKSLRQSR-SRSRSKGGSRSRSRSRSKSKDKRKGRKRSR 361
Query: 341 VDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDET 400
+S +S S ++R+ ++ K+ K D R + S S
Sbjct: 362 EESRSRSRSRSKSERSRKRGSKRDSKAGSSKK--------KKKEDTDRSQSRSPSRSVSK 413
Query: 401 DGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNK 460
+ A S G ++Q + ++ KP+LP S+ +S K AS K +
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP-SESRSRSKSAS---KTR 469
Query: 461 TASSTTKEKETKLPLLSRVPSAGSS 485
+ S + ++ P SR S S
Sbjct: 470 SRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 45.1 bits (105), Expect = 4e-04
Identities = 69/321 (21%), Positives = 110/321 (34%), Gaps = 16/321 (4%)
Query: 42 ESPGDRKQSIIDFFKPASKQDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKP 101
+ PG R++ + S+ S +KS + G S+ S + + R S +
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHS-RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 102 KRVPPEKSPIIEAFMKGVKE--HHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPK 159
R E KE H +SR A + + N+ P S P
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS-RSPS 292
Query: 160 EMKS-LKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSS 218
KS K + RS ERR E ++ RG++ S +Q+ + SRS S
Sbjct: 293 RHKSKSKSRSRSQERRV-----EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 219 RSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSS 278
S + + S + ER KR K + + + + +S
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 279 IERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKR 338
K R+ + ++ G+ N +R RS S+S SK N E R R
Sbjct: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS------KSKPNLPSESRSR 461
Query: 339 NSVDSDLKSTRESMIPKARES 359
+ S +S +S A S
Sbjct: 462 SKSASKTRSRSKSRSRSASRS 482
Score = 34.7 bits (78), Expect = 0.55
Identities = 52/216 (24%), Positives = 87/216 (40%), Gaps = 17/216 (7%)
Query: 422 NSDQIQVAGTKETKMQKPHLPLSQEKSAIKKAS-NLQKNKTASSTTKEKETKLPLLSRVP 480
N +I++ K ++ S+ S + S + +K+++ S ++K +K SR
Sbjct: 166 NGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSR-- 223
Query: 481 SAGSSLVPLNAKNCALPVSKKDKERSSSKECS---GHSTESTKHKEHKAKTNKADSNVSS 537
S S +++ + SKK+K RS SKE S HS ++ K K +N +
Sbjct: 224 SGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 538 GK-ISGGPLRSEYGTPTKSPPAALEVVP---CIPSPAAPSDKAPSEGESSGNSNAGS--- 590
GK S P R + + ++S V S +K+ + S S GS
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 591 ----SALKRKLRGDFDSDEESLGYNLDSDEEEETLK 622
S K K +G S EES + + E + K
Sbjct: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRK 379
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 52.4 bits (124), Expect = 3e-06
Identities = 106/551 (19%), Positives = 190/551 (34%), Gaps = 93/551 (16%)
Query: 87 EQFERKLSSPKESKPKRVPPEK----------SPIIEAFMKGVKEH--HEDHG---IHES 131
+ F R +S +ESK P + SP+ + + +K+ H++H +
Sbjct: 1488 KNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRE 1547
Query: 132 RRPC-LSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDR 190
R P S +++ N PS + SL+++H SP +R N + +R
Sbjct: 1548 RTPRGPSERTRHNPSWRNHRSPSER---SQRSSLERRHHSPSQRSHCSPSRKNHSSPSER 1604
Query: 191 GKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELK 250
+ + + E + S R L S S S P
Sbjct: 1605 SWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGP----------------------- 1641
Query: 251 RLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHL 310
Q SE S S S +SS ER+++ ++ + +++ S E H
Sbjct: 1642 ----SQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGP--SERSHCSPSERRHR 1695
Query: 311 SRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQ 370
S + S S + R S S + + S ++ S E+R P +
Sbjct: 1696 SPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSE 1755
Query: 371 KEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAG 430
+ H + E + PS+ S + + + HHS
Sbjct: 1756 R----SHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSE-------- 1803
Query: 431 TKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEK-ETKLPLLSRVPSAGSSLVPL 489
++ H PL + + ++ + S+ ++ S + E+ ++ S PS S L PL
Sbjct: 1804 ------RRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPL 1857
Query: 490 NAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEY 549
++ R S E GHS+ +++++ S + G+ S RS
Sbjct: 1858 ------------ERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
Query: 550 GTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGDFDSDEESLG 609
SP E+ P PS S + + S LK L+ F + S
Sbjct: 1906 ERTRHSPS---EMRPGRPS---------GRNHCSPSERSRRSPLKEGLKYSFPGERPS-- 1951
Query: 610 YNLDSDEEEET 620
++L D + +T
Sbjct: 1952 HSLSRDFKNQT 1962
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 52.0 bits (123), Expect = 3e-06
Identities = 120/588 (20%), Positives = 207/588 (35%), Gaps = 108/588 (18%)
Query: 33 AHAAAGKRTESPGDRKQSIIDFFKPASKQDRHMLDS--PQKSNIKYGGSRLSITGTEQFE 90
A A + ++ I F+ ++K L + P K S + + E
Sbjct: 35 AKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEE 94
Query: 91 RKLSSPKESKP----KRV--PPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLA 144
++ P K KRV PP K+ + +E +D + ++ + K A
Sbjct: 95 EEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQA 154
Query: 145 KGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDR-------GKTNADS 197
K K+ KK +S + + KN + + +T A
Sbjct: 155 KAA--------------KAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPP 200
Query: 198 KKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQM 257
K + +S S SS SS S EE A + K + K+Q+
Sbjct: 201 KPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPK------------KTVPKKQV 248
Query: 258 EQR--INSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRS 315
+ + + + + SS S SS + + +EQ+K PG S+V +
Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEE----EEQKKPMKNKPGP--YSSVPPPSAPPPKK 302
Query: 316 SSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFI 375
S + P A KQ P + +S D S+ E EK+P K +
Sbjct: 303 SLGTQPPKKAVEKQQ--PVESSEDSSDESDSSSEE-----------EKKPP-----TKAV 344
Query: 376 KHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETK 435
A P + + S + SD +D S APS + T+NS TK
Sbjct: 345 VSKATTKPPPAKKAAESSSDSSD-SDSSEDDEAPSKPAGT----TKNSSNKPAVTTKSPA 399
Query: 436 MQKPHLPLSQ----EKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNA 491
++ P +K +KA + + +SS+ +EK K+ ++ + + + L A
Sbjct: 400 VKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPA 459
Query: 492 KNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGT 551
K P +D S ++S+ +E + KT+K+ K++GG
Sbjct: 460 KQA--PQGSRD---------SSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG-------- 500
Query: 552 PTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRG 599
PS A + K +E +S +S+ S + KL+G
Sbjct: 501 -------------AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKG 535
Score = 40.4 bits (93), Expect = 0.010
Identities = 65/254 (25%), Positives = 95/254 (37%), Gaps = 56/254 (22%)
Query: 439 PHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPV 498
P L KKA K ASS+ E ++ + P A + VP AK LP
Sbjct: 64 PERKLQANGPVAKKAK-----KKASSSDSEDSSEEEEEVQGPPAKKAAVP--AKRVGLPP 116
Query: 499 SK---KDKERSSSKECSGHSTESTKHKE-----------------HKAKTNKADSNVSSG 538
K K E SSS+E S E + K+ KAK++ +DS+ SS
Sbjct: 117 GKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSE 176
Query: 539 ---------KISGGPLRSEYGTPTKSPPAALEVVPCIPS-PAAPSDKAPSEGESSGNSNA 588
KI+ ++++ TK+PP P I + AA S + S SS +S
Sbjct: 177 DEPPKNQKPKITPVTVKAQ----TKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEE 232
Query: 589 GSSALKRK--------------LRGDFDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQ 634
+A K + + S + SDEEEE K ++ ++
Sbjct: 233 EKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPG-PYSS 291
Query: 635 TPAATGKPPALSKG 648
P + PP S G
Sbjct: 292 VPPPSAPPPKKSLG 305
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 52.0 bits (123), Expect = 3e-06
Identities = 100/515 (19%), Positives = 175/515 (33%), Gaps = 60/515 (11%)
Query: 92 KLSSPKESKPKRVPPEKSPIIEAFMKGVKEHHED--HGIHESRRPCLSLASKYLAKGTNI 149
K S K+ PE I+E K E + HE+ + S +S TN
Sbjct: 128 KKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSE----TNP 183
Query: 150 YVPSSYHLPKEMKSLKKKH-RSPERRKSLFIH-ENNEKNDRDRGKTNAD------SKKQT 201
+S + K KK ++ ++ + F+H +NN K D R KT+ D S+
Sbjct: 184 ESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSL 243
Query: 202 TVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRI 261
V + S + + R++ + + + L Y ++ K +K +
Sbjct: 244 NVDFLMLVGQSDDESINFDAWLRNYSQNN--SKNYSLKYTKYTKKDTKKNAKKSSDAESE 301
Query: 262 NSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPG------------KNNLSNVENGH 309
+S+++ ++ + + K K ++ + D G K L +
Sbjct: 302 DSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKK 361
Query: 310 LSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEK------ 363
++K S E A +N +K + D K ++ ES LE
Sbjct: 362 DTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKD 421
Query: 364 ----RPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHS 419
+ D +K +K+ T D D K DE G S + +
Sbjct: 422 EKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKK----DSKKDDKKKDA 477
Query: 420 TRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKE--KETKLPLLS 477
+N++ ++ E K K H S+EK KK K ST E + +K +
Sbjct: 478 KKNAESTEMESDLELKKDKKH---SKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKT 534
Query: 478 RVPSAGS---SLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSN 534
GS S L + + D ++SK S + K N+
Sbjct: 535 STKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEK 594
Query: 535 VSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSP 569
S+G++ P++ P P +PSP
Sbjct: 595 ASTGRV----------PPSREKPPLPACEPSLPSP 619
Score = 42.7 bits (99), Expect = 0.002
Identities = 78/369 (21%), Positives = 140/369 (37%), Gaps = 47/369 (12%)
Query: 141 KYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQ 200
K K ++ S K+ K +KK + +++K + ++ E D + G + D +K
Sbjct: 290 KNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKD--VKKDTESTDAESGDSK-DERKD 346
Query: 201 TTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQR 260
T + + + + + + S A+ R LK+ K +++
Sbjct: 347 TKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARND--------SRNLKKASKNDDKKK 398
Query: 261 INSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSW 320
+ +FS S L+S +K + + ++ + D N + K S
Sbjct: 399 DAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGK 458
Query: 321 EPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIAL 380
+ G K +K +K+K D K ES ES LE + D H KEK
Sbjct: 459 KDEKKGKKDSKKDDKKK------DAKKNAES---TEMESDLELKKDKKHSKEK------- 502
Query: 381 KTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTK-ETKMQKP 439
G +DI K+ +T+ + A S +G + S +I+ + T+ E + KP
Sbjct: 503 --KGS---KKDIKKDARKDTESTDAEF--DESSKTGF---KTSTKIKGSDTESEESLYKP 552
Query: 440 ----HLPLSQEKSAIKKASNLQKNK----TASSTTKEKETKLPLLSRVPSAGSSLVPLNA 491
+ S SA K L+ + ++ TT ++ + RVP + PL A
Sbjct: 553 GAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREK-PPLPA 611
Query: 492 KNCALPVSK 500
+LP K
Sbjct: 612 CEPSLPSPK 620
Score = 33.9 bits (76), Expect = 0.93
Identities = 78/448 (17%), Positives = 151/448 (33%), Gaps = 42/448 (9%)
Query: 242 SYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNN 301
++ ++ E K+ + E+ + + S+ S ++ E K ++ ++QN+ K
Sbjct: 108 THLKKAEYKKSKDEKGGTPLKKD---SKKKGGSYATNPESKQIVEEKTKRQNEA--DKTP 162
Query: 302 LSNVENGHLSRKRSSSDSWEPTSAGSK--QNKFPEKRKRNSVDSDLKSTRESMIPKARES 359
L + S+K SS P S SK +K K++S +S +T +
Sbjct: 163 LKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKK 222
Query: 360 FLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGN----- 414
L++ + +L D L L S + S D + +NS N
Sbjct: 223 DLKRSKTSNDPISEICSENSLNV--DFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKY 280
Query: 415 -------SGHHSTRNSD---QIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASS 464
+ ++ ++SD + K++K K ++ +K +KK + ++ S
Sbjct: 281 TKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDS 340
Query: 465 TTKEKETK-----------------LPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSS 507
+ K+TK P + S + +++N DK++ +
Sbjct: 341 KDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDA 400
Query: 508 SKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIP 567
K +ES + K K D S E T S P
Sbjct: 401 KKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKD 460
Query: 568 SPAAPSDKAPSEGESSGNSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEEI 627
D + + NA S+ ++ L D D +++ K E
Sbjct: 461 EKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTEST 520
Query: 628 MALNFNQTPAATGKPPALSKGLRSQSSD 655
A F+++ K KG ++S +
Sbjct: 521 DA-EFDESSKTGFKTSTKIKGSDTESEE 547
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 51.2 bits (121), Expect = 6e-06
Identities = 85/364 (23%), Positives = 141/364 (38%), Gaps = 57/364 (15%)
Query: 380 LKTPGDVLR-LEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQK 438
LK GD R + S S + SS+ + S+S +S S+ +S + + T K
Sbjct: 136 LKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSK 195
Query: 439 PHLPLSQEK-----------SAIKKASNLQKNKTASSTTKEKETKLPL------------ 475
PH + + K SA K+ S + S+ K KE K PL
Sbjct: 196 PHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK-PLKEEKIVPKMAFK 254
Query: 476 ----LSRVPSAGSSLVPLNAKNCALPVSKK----DKERSSSKECSGHSTESTKHKEHKA- 526
+S+ P S+L+ + + SK+ D E S+K+ S+E+ A
Sbjct: 255 EPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAP 314
Query: 527 ----------KTNKADSNVSSGKISGGPLRSEYGTPTKSP-PAALEVVPCIPSPAAP--S 573
K K S+V GK+ + SE KS P ++V S S
Sbjct: 315 PLILTCSADKKQIKDKSHVKMGKVK---IESETSEKKKSTLPPFDDIVDPNDSDVEENIS 371
Query: 574 DKAPSEGESSGNSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEEIMALNFN 633
K+ SE S +S++ SS+ + S+ +L SD+ EE +E+ +
Sbjct: 372 SKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEM 431
Query: 634 QTPAATG----KPPALSKGLRSQSSDYTGHVH---PGTYTNTLERLVKEMEDTQRLDELQ 686
+ P G + +LS G S+SS + +H P T + E++ + +
Sbjct: 432 ERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSD 491
Query: 687 KQLQ 690
KQ++
Sbjct: 492 KQIK 495
Score = 43.5 bits (101), Expect = 0.001
Identities = 54/233 (23%), Positives = 93/233 (39%), Gaps = 29/233 (12%)
Query: 303 SNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSD-----LKSTRESMIPKAR 357
S+ + S SSS S TS E +++ S DS K ++
Sbjct: 171 SSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSK 230
Query: 358 ESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGH 417
ES + + + P ++EK + +A K P + +SKEP +++ + S
Sbjct: 231 ESSKKPKENKPLKEEKIVPKMAFKEP------KPMSKEPKPDSNLLTITSGQDKKAPSKR 284
Query: 418 HSTRNSDQIQVAGTKETKMQ--------KPHLPL--SQEKSAIKKASNLQ--KNKTASST 465
+S+++ K++ + P L L S +K IK S+++ K K S T
Sbjct: 285 PPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESET 344
Query: 466 TKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTES 518
+++K++ LP + S V N SK D E+ S S S+ S
Sbjct: 345 SEKKKSTLPPFDDIVDPNDSDVEENIS------SKSDSEQPSPASSSSSSSSS 391
Score = 35.0 bits (79), Expect = 0.42
Identities = 39/142 (27%), Positives = 60/142 (42%), Gaps = 6/142 (4%)
Query: 210 NNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENS-FS 268
++SS S SS SS S S + S S+ + +L + KE+ + S F
Sbjct: 160 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFK 219
Query: 269 EASSLSLKSSIERKYKPRQEQ-RKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGS 327
E S KSS E KP++ + K+ I+P ++ E +S K DS T
Sbjct: 220 EPSRDHNKSSKESSKKPKENKPLKEEKIVP---KMAFKEPKPMS-KEPKPDSNLLTITSG 275
Query: 328 KQNKFPEKRKRNSVDSDLKSTR 349
+ K P KR S +L + +
Sbjct: 276 QDKKAPSKRPPISDSEELSAKK 297
Score = 31.2 bits (69), Expect = 6.1
Identities = 31/141 (21%), Positives = 52/141 (36%), Gaps = 9/141 (6%)
Query: 92 KLSSPKESKPKRVPPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLAKGTNIYV 151
K+ S K K P I++ V+E+ E P S +S ++ +
Sbjct: 339 KIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSS-----SSSFT 393
Query: 152 PSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNN 211
PS ++S+ K S + + E+N+ + N + V+ +D
Sbjct: 394 PSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSD---- 449
Query: 212 SSRSLSSRSSLSRHHPEESPL 232
S S SS +S HH PL
Sbjct: 450 GSDSESSSASSPLHHEPPPPL 470
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 50.8 bits (120), Expect = 7e-06
Identities = 107/526 (20%), Positives = 198/526 (37%), Gaps = 74/526 (14%)
Query: 77 GGSRLSITGTEQFERKL---SSPKESKPKRVPPEKSPIIEAFMKGVKEHHEDHGIHESRR 133
G S+ S T+ + + SS KES+ ++ EK+ G K+ + H E+
Sbjct: 149 GSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRET-- 206
Query: 134 PCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKT 193
P SY K + S K++ RSP R+ S ++++++D G +
Sbjct: 207 ------------------PKSY---KTVDSPKRRSRSPHRKWS----DSSKQDDSPSGAS 241
Query: 194 -----NADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLG---------AKFQLS 239
+ + T + D + S S S R S+S + E S ++ Q S
Sbjct: 242 YGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRS 301
Query: 240 LASYCRERELKRLRKEQMEQRINSENSFSEASSLSL-KSSIERKYKPRQEQRKQNDIIPG 298
++ Y R R R R S +SS L K S+ R P ++ K P
Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361
Query: 299 KNNLSNVENGHLSRKRSSSDSWEP----------TSAGSKQNKFPEKRKRNSVDS--DLK 346
S + H +KRSSS S +S G++ ++ ++R + + D K
Sbjct: 362 ---YSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGK 418
Query: 347 STRES--MIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSS 404
++ S +P+ S +E + G K K + + L+ L +++ ++ + S
Sbjct: 419 ESKGSPVFLPRKENSSVEAKDSGLESK-KLPRSVKLEKSAPDTELVNVTHLNTEVKNSSD 477
Query: 405 AGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLS-QEKSAIKKASNLQKNKTAS 463
G + NS H ++ ++ GT+++K P++ +E+ K + + +T
Sbjct: 478 TGKVKLDE-NSEKHLVKD---LKAQGTRDSK------PIALKEEIVTPKETETSEKETPP 527
Query: 464 STTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKE 523
PL + P + +P ALP + S+ ST
Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPS 587
Query: 524 HKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSP 569
+KT+ S +S ++++ P +P +P P
Sbjct: 588 THSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLP 633
Score = 48.9 bits (115), Expect = 3e-05
Identities = 99/517 (19%), Positives = 192/517 (37%), Gaps = 54/517 (10%)
Query: 107 EKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKK 166
E+ ++ + +H +D G+ L K L + +I S L +
Sbjct: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR 93
Query: 167 KHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSR-SSLSRH 225
+ R + ++ + R + KQT ++ ++ S S+ R S S+
Sbjct: 94 RENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKR 153
Query: 226 HPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKP 285
EE+ K Q++ +S +E +L KE+ + ++ + S K + YK
Sbjct: 154 SNEETDDYGKAQVAKSS-SKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKT 212
Query: 286 --------RQEQRKQNDIIPGKNNLSNVENGH-----LSRKRSSS--DSWE--PTSAGSK 328
R RK +D ++ S G SR +SS DS++ P S +
Sbjct: 213 VDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRR 272
Query: 329 QNKFPEKRKRNSVDSDLKST------RESMIPKARESFLEKRPDGPHQKEKFIKHIALKT 382
Q+ P ++ ++ S +S + S+ P +R G + + ++
Sbjct: 273 QSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRS 332
Query: 383 PGDVLRLEDISKEPSDETDG-SSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHL 441
L +S+ P S +P+ S +S HS + + ++ + + L
Sbjct: 333 SSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSR---SRHSSISPVRL 389
Query: 442 PLSQEKSAIKKASNLQKNKTASSTT-----KEKETKLPLLSRVPSAGSSLVPLNAKNCAL 496
PL+ A + S +K + A++ KE + L R ++ ++ L
Sbjct: 390 PLNSSLGA--ELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKL 447
Query: 497 PVSKKDKERSSSKECSG---------HSTESTKHK------EHKAKTNKADSNVSSGKIS 541
P S K ++ + E +S+++ K K +H K KA S I+
Sbjct: 448 PRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIA 507
Query: 542 GGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPS 578
L+ E TP ++ + E P +P+ A+P P+
Sbjct: 508 ---LKEEIVTPKETETSEKETPPPLPTIASPPPPLPT 541
Score = 34.7 bits (78), Expect = 0.55
Identities = 50/258 (19%), Positives = 102/258 (39%), Gaps = 23/258 (8%)
Query: 340 SVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDE 399
S DSD S + RE+ + D + K +H + D+L+ + KE S E
Sbjct: 77 SSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKH-RHHQHRRSRDLLKAKQTEKEKSQE 135
Query: 400 TDGSSAGLAPSNSGNSGHHSTRNSD----QIQVAGTKETKMQKPHLPLSQEKSAIKKASN 455
S + SG+S + D Q+ + +KE++ K H ++++ +K
Sbjct: 136 VSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSG-- 193
Query: 456 LQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHS 515
+K S + +++ET P + ++ + K + +K + S + +
Sbjct: 194 ---HKDRSKSHRKRET--------PKSYKTVD--SPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 516 TESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDK 575
+ + ++++ + + S K G R + +P P+A + PSP + +
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 576 AP---SEGESSGNSNAGS 590
+ S SS +GS
Sbjct: 301 SVSPYSRRRSSSYERSGS 318
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 50.8 bits (120), Expect = 7e-06
Identities = 107/526 (20%), Positives = 198/526 (37%), Gaps = 74/526 (14%)
Query: 77 GGSRLSITGTEQFERKL---SSPKESKPKRVPPEKSPIIEAFMKGVKEHHEDHGIHESRR 133
G S+ S T+ + + SS KES+ ++ EK+ G K+ + H E+
Sbjct: 149 GSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRET-- 206
Query: 134 PCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKT 193
P SY K + S K++ RSP R+ S ++++++D G +
Sbjct: 207 ------------------PKSY---KTVDSPKRRSRSPHRKWS----DSSKQDDSPSGAS 241
Query: 194 -----NADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLG---------AKFQLS 239
+ + T + D + S S S R S+S + E S ++ Q S
Sbjct: 242 YGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRS 301
Query: 240 LASYCRERELKRLRKEQMEQRINSENSFSEASSLSL-KSSIERKYKPRQEQRKQNDIIPG 298
++ Y R R R R S +SS L K S+ R P ++ K P
Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361
Query: 299 KNNLSNVENGHLSRKRSSSDSWEP----------TSAGSKQNKFPEKRKRNSVDS--DLK 346
S + H +KRSSS S +S G++ ++ ++R + + D K
Sbjct: 362 ---YSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGK 418
Query: 347 STRES--MIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSS 404
++ S +P+ S +E + G K K + + L+ L +++ ++ + S
Sbjct: 419 ESKGSPVFLPRKENSSVEAKDSGLESK-KLPRSVKLEKSAPDTELVNVTHLNTEVKNSSD 477
Query: 405 AGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLS-QEKSAIKKASNLQKNKTAS 463
G + NS H ++ ++ GT+++K P++ +E+ K + + +T
Sbjct: 478 TGKVKLDE-NSEKHLVKD---LKAQGTRDSK------PIALKEEIVTPKETETSEKETPP 527
Query: 464 STTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKE 523
PL + P + +P ALP + S+ ST
Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPS 587
Query: 524 HKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSP 569
+KT+ S +S ++++ P +P +P P
Sbjct: 588 THSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLP 633
Score = 48.9 bits (115), Expect = 3e-05
Identities = 99/517 (19%), Positives = 192/517 (37%), Gaps = 54/517 (10%)
Query: 107 EKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKK 166
E+ ++ + +H +D G+ L K L + +I S L +
Sbjct: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR 93
Query: 167 KHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSR-SSLSRH 225
+ R + ++ + R + KQT ++ ++ S S+ R S S+
Sbjct: 94 RENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKR 153
Query: 226 HPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKP 285
EE+ K Q++ +S +E +L KE+ + ++ + S K + YK
Sbjct: 154 SNEETDDYGKAQVAKSS-SKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKT 212
Query: 286 --------RQEQRKQNDIIPGKNNLSNVENGH-----LSRKRSSS--DSWE--PTSAGSK 328
R RK +D ++ S G SR +SS DS++ P S +
Sbjct: 213 VDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRR 272
Query: 329 QNKFPEKRKRNSVDSDLKST------RESMIPKARESFLEKRPDGPHQKEKFIKHIALKT 382
Q+ P ++ ++ S +S + S+ P +R G + + ++
Sbjct: 273 QSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRS 332
Query: 383 PGDVLRLEDISKEPSDETDG-SSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHL 441
L +S+ P S +P+ S +S HS + + ++ + + L
Sbjct: 333 SSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSR---SRHSSISPVRL 389
Query: 442 PLSQEKSAIKKASNLQKNKTASSTT-----KEKETKLPLLSRVPSAGSSLVPLNAKNCAL 496
PL+ A + S +K + A++ KE + L R ++ ++ L
Sbjct: 390 PLNSSLGA--ELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKL 447
Query: 497 PVSKKDKERSSSKECSG---------HSTESTKHK------EHKAKTNKADSNVSSGKIS 541
P S K ++ + E +S+++ K K +H K KA S I+
Sbjct: 448 PRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIA 507
Query: 542 GGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPS 578
L+ E TP ++ + E P +P+ A+P P+
Sbjct: 508 ---LKEEIVTPKETETSEKETPPPLPTIASPPPPLPT 541
Score = 34.7 bits (78), Expect = 0.55
Identities = 50/258 (19%), Positives = 102/258 (39%), Gaps = 23/258 (8%)
Query: 340 SVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDE 399
S DSD S + RE+ + D + K +H + D+L+ + KE S E
Sbjct: 77 SSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKH-RHHQHRRSRDLLKAKQTEKEKSQE 135
Query: 400 TDGSSAGLAPSNSGNSGHHSTRNSD----QIQVAGTKETKMQKPHLPLSQEKSAIKKASN 455
S + SG+S + D Q+ + +KE++ K H ++++ +K
Sbjct: 136 VSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSG-- 193
Query: 456 LQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHS 515
+K S + +++ET P + ++ + K + +K + S + +
Sbjct: 194 ---HKDRSKSHRKRET--------PKSYKTVD--SPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 516 TESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDK 575
+ + ++++ + + S K G R + +P P+A + PSP + +
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 576 AP---SEGESSGNSNAGS 590
+ S SS +GS
Sbjct: 301 SVSPYSRRRSSSYERSGS 318
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 50.4 bits (119), Expect = 1e-05
Identities = 118/570 (20%), Positives = 216/570 (37%), Gaps = 78/570 (13%)
Query: 132 RRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHEN-NEKNDR-- 188
R P L SK +K ++ S +K+ ++ + + K FI + NE+ R
Sbjct: 247 RNPAPRLKSKKWSKKFQSFIESCL-----VKNHSQRPATEQLMKHPFIRDQPNERQVRIQ 301
Query: 189 -----DRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKF-QLSLAS 242
DR K K +T + + S S + P ES L F +L LA+
Sbjct: 302 LKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLAN 361
Query: 243 YCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPR-QEQRKQNDIIPGKNN 301
R L+R + EQ +QR N E+ + + +++ + R +EQ+++ + +
Sbjct: 362 KERSEALRRQQLEQ-QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE 420
Query: 302 LSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMI----PKAR 357
+ +R K+ + E+R+ + LK R+ ++ +
Sbjct: 421 REQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQE 480
Query: 358 ESFLEKRP-------DGPHQKEKFIKHI----ALKTPGDVLRL-EDISKEPSDETDGSSA 405
+ +EK+P P +K + K I A+K+ G L + + ++P+ G
Sbjct: 481 QRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQE 540
Query: 406 GLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASST 465
L N H Q + + P LP EK ++S L++ +
Sbjct: 541 AL------NVTSHRVEMPRQ-----NSDPTSENPPLPTRIEK--FDRSSWLRQEEDIPPK 587
Query: 466 TKEKETKL-PLLSR--VPSAGSSL------VPLNAKNCAL----PVSKKDKERSSSKECS 512
++ T + P L+R P GS+L P+ A N L P+ + +R+SS S
Sbjct: 588 VPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSS 647
Query: 513 GHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAP 572
ST S++ + G +G R+ +KS E P +P A
Sbjct: 648 SSSTPSSQ--------PSSQGGSQPGSQAGSSERTRVRANSKS-----EGSPVLPHEPAK 694
Query: 573 SDKAPSEGESSGNSNAGSSALKRKLRGDFDSDEES------LGYNLDSDEEEETLKSLEE 626
S + + A +AL ++LR + +E + Y+ S+E E + + E+
Sbjct: 695 VKPEESRDITRPSRPADLTALAKELR-ELRIEETNRPMKKVTDYSSSSEESESSEEEEED 753
Query: 627 IMALNFNQTPAATGKPPALSKGLRSQSSDY 656
+ + T A + P + G + Y
Sbjct: 754 GESETHDGTVAVSDIPRLIPTGAPGSNEQY 783
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 50.1 bits (118), Expect = 1e-05
Identities = 77/345 (22%), Positives = 131/345 (37%), Gaps = 64/345 (18%)
Query: 205 EADIFNNSSRSLSSRSSLS-RHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINS 263
E D RS S R SLS R P S + + S +REL+R ++ Q +R
Sbjct: 250 EIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAK 309
Query: 264 ENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPT 323
E S S+ +ER+ +E+ H SR RS +
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRER-------------------HRSRSRSRDRKGDRR 350
Query: 324 SAGSKQNKFPEKRKRNSVDSDLK--STRESMIPKARESFLEKRPDGPHQKEKFIKHIALK 381
++ K E+ +R D D + + RE ++RE E+R G +++K
Sbjct: 351 DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKK-------- 402
Query: 382 TPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHL 441
KE D+ H + + + ++ ++ H
Sbjct: 403 -----------HKEDKDD---------------RRHRDDKRDSKKEKKHSRSRSRERKHR 436
Query: 442 PLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAG-SSLVPLNAKNCALPVSK 500
S+ ++A K++ + K K++ + KE K SR S G + V + K P +
Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKE-KSNKRSRSGSQGRTDSVEKSKKREHSPSKE 495
Query: 501 KDKERSSSKECS---GHS---TESTKHKEHKAKTNKADSNVSSGK 539
K ++RS SKE S HS +S KH ++++ + +S K
Sbjct: 496 KSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHK 540
Score = 35.0 bits (79), Expect = 0.42
Identities = 36/166 (21%), Positives = 63/166 (37%), Gaps = 6/166 (3%)
Query: 159 KEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGK---TNADSKKQTTVAEADIFNNSSRS 215
+E + + + RS E+R + E K D+D + DSKK+ + + RS
Sbjct: 378 REKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRS 437
Query: 216 LS---SRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASS 272
S + SR +E K + S R R + R + +E+ E+S S+ S
Sbjct: 438 RSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKS 497
Query: 273 LSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSD 318
S ER +K K + ++E ++ + D
Sbjct: 498 RKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 50.1 bits (118), Expect = 1e-05
Identities = 79/335 (23%), Positives = 132/335 (39%), Gaps = 44/335 (13%)
Query: 164 LKKKHRSPERRKSLFI----HENNEKNDRDR------GKTNADSKKQTTVAEADIFNNSS 213
+ +K R+P S+ H+ EK R R G ++++S+ +T + + SS
Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSS 538
Query: 214 RSLSSRSSL--------SRHHPEESPLGAKFQLSLASYCRERELK--RLRKEQMEQRINS 263
S SSR+S RH SP + SY R +++ R R + ++R ++
Sbjct: 539 SSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSN 598
Query: 264 ENSFSEASSLSLKSSIERKY-KPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEP 322
NS + S ER+ + R R+ N ++ + + +R +
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSR----DRRKIDDQRGNLSGNSH 654
Query: 323 TSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIA--- 379
G + + +K + S+D D K K RE +KR + ++EK K +
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDRKKK-----DKEREREQDKRKEKQKREEKDFKFSSQDD 709
Query: 380 -LKTPGDVLRLEDISKEPS------DETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTK 432
LK + R S S D S + +SG S+ S +K
Sbjct: 710 RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSK 769
Query: 433 ETKMQKPHLPLSQ--EKS--AIKKASNLQKNKTAS 463
E K +KP S+ EKS + KKAS K+K+ S
Sbjct: 770 EKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 50.1 bits (118), Expect = 1e-05
Identities = 79/335 (23%), Positives = 132/335 (39%), Gaps = 44/335 (13%)
Query: 164 LKKKHRSPERRKSLFI----HENNEKNDRDR------GKTNADSKKQTTVAEADIFNNSS 213
+ +K R+P S+ H+ EK R R G ++++S+ +T + + SS
Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSS 538
Query: 214 RSLSSRSSL--------SRHHPEESPLGAKFQLSLASYCRERELK--RLRKEQMEQRINS 263
S SSR+S RH SP + SY R +++ R R + ++R ++
Sbjct: 539 SSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSN 598
Query: 264 ENSFSEASSLSLKSSIERKY-KPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEP 322
NS + S ER+ + R R+ N ++ + + +R +
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSR----DRRKIDDQRGNLSGNSH 654
Query: 323 TSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIA--- 379
G + + +K + S+D D K K RE +KR + ++EK K +
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDRKKK-----DKEREREQDKRKEKQKREEKDFKFSSQDD 709
Query: 380 -LKTPGDVLRLEDISKEPS------DETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTK 432
LK + R S S D S + +SG S+ S +K
Sbjct: 710 RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSK 769
Query: 433 ETKMQKPHLPLSQ--EKS--AIKKASNLQKNKTAS 463
E K +KP S+ EKS + KKAS K+K+ S
Sbjct: 770 EKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
[Homo sapiens]
Length = 2269
Score = 48.5 bits (114), Expect = 4e-05
Identities = 75/390 (19%), Positives = 146/390 (37%), Gaps = 28/390 (7%)
Query: 166 KKHRSPERRKSLFIHENNEKNDRDRGKTNADSK----KQTTVAEADIFNNSSRSLSSRSS 221
+K RR F N K D K+ + K K T ++ + ++S SSR++
Sbjct: 1426 QKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTA 1485
Query: 222 LSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRIN-SENSFSEASSLSLKSSIE 280
H + + + +S E +R R + SE+ ++ + SL SS
Sbjct: 1486 YLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSAS 1545
Query: 281 RKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNS 340
+ +E + + ++ LS N ++R R++ P S + + +++
Sbjct: 1546 SSSEESKESSRARE-SSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYL 1604
Query: 341 VDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDET 400
DSD S I KAR K ++ A + + D+ + S E+
Sbjct: 1605 SDSDNNSLETGEILKARAG----------NNRKVLRKCAAVAANKIKLMSDVEENSSSES 1654
Query: 401 DGSSAGLAPSNSGNSG-----HHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASN 455
S L N+ H+S +E K + LP+S +A SN
Sbjct: 1655 VCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTA---QSN 1711
Query: 456 LQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKD---KERSSSKECS 512
+ +++ S + E + ++ + + S P +K L + + K S C+
Sbjct: 1712 VDESENRDSES-ESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACN 1770
Query: 513 GHSTESTKHKEHKAKTNKADSNVSSGKISG 542
+ ST ++ KA++ +++ G+ G
Sbjct: 1771 RTAGPSTSVQKLKAESISEEADSEPGRSGG 1800
>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
[Homo sapiens]
Length = 2320
Score = 48.5 bits (114), Expect = 4e-05
Identities = 75/390 (19%), Positives = 146/390 (37%), Gaps = 28/390 (7%)
Query: 166 KKHRSPERRKSLFIHENNEKNDRDRGKTNADSK----KQTTVAEADIFNNSSRSLSSRSS 221
+K RR F N K D K+ + K K T ++ + ++S SSR++
Sbjct: 1426 QKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTA 1485
Query: 222 LSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRIN-SENSFSEASSLSLKSSIE 280
H + + + +S E +R R + SE+ ++ + SL SS
Sbjct: 1486 YLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSAS 1545
Query: 281 RKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNS 340
+ +E + + ++ LS N ++R R++ P S + + +++
Sbjct: 1546 SSSEESKESSRARE-SSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYL 1604
Query: 341 VDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDET 400
DSD S I KAR K ++ A + + D+ + S E+
Sbjct: 1605 SDSDNNSLETGEILKARAG----------NNRKVLRKCAAVAANKIKLMSDVEENSSSES 1654
Query: 401 DGSSAGLAPSNSGNSG-----HHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASN 455
S L N+ H+S +E K + LP+S +A SN
Sbjct: 1655 VCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTA---QSN 1711
Query: 456 LQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKD---KERSSSKECS 512
+ +++ S + E + ++ + + S P +K L + + K S C+
Sbjct: 1712 VDESENRDSES-ESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACN 1770
Query: 513 GHSTESTKHKEHKAKTNKADSNVSSGKISG 542
+ ST ++ KA++ +++ G+ G
Sbjct: 1771 RTAGPSTSVQKLKAESISEEADSEPGRSGG 1800
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 47.8 bits (112), Expect = 6e-05
Identities = 90/417 (21%), Positives = 160/417 (38%), Gaps = 99/417 (23%)
Query: 117 KGVKEHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKS 176
K VKE+ ++ G + + + T P + L K+ K K+ R + K+
Sbjct: 1264 KAVKENDKEKGKEKEKEK---------KEKTPATTPEARVLGKDGKEKPKEERPNKDEKA 1314
Query: 177 LFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKF 236
E K+D+++ K + K + + + N S+S R E+ P
Sbjct: 1315 RETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQERER------EKEP----- 1363
Query: 237 QLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKP---RQEQRKQN 293
RER++ + +M+ + N + S SLKS + R P R+++R++
Sbjct: 1364 -------SRERDIAK----EMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKI 1412
Query: 294 DIIPGKNNLSNVENGHLSRKRSSSDSW----EPTSAGSKQNKFPEKRKRNSVDSDLKSTR 349
D P ++ S V++ + K SS+ + P + SK+ + +K DL +R
Sbjct: 1413 DTHPSPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKK--------DLDKSR 1464
Query: 350 ESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAP 409
E ++RE ++ D +KE+ H + D D++K +E
Sbjct: 1465 E----RSRE---REKKDEKDRKERKRDH----SNNDREVPPDLTKRRKEEN--------- 1504
Query: 410 SNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEK 469
G S H S E+ + P+ P ++K K S+ K K + S EK
Sbjct: 1505 GTMGVSKHKS-------------ESPCESPY-PNEKDKEKNKSKSS-GKEKGSDSFKSEK 1549
Query: 470 ETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKA 526
+ ++ S G S+ DKE+ KE S + K HK+
Sbjct: 1550 ------MDKISSGGKK------------ESRHDKEKIEKKEKRDSSGGKEEKKHHKS 1588
Score = 40.4 bits (93), Expect = 0.010
Identities = 82/394 (20%), Positives = 135/394 (34%), Gaps = 61/394 (15%)
Query: 261 INSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSW 320
I S + E+S+ S ER + K + P K N SN +G S K +
Sbjct: 1213 IGSASKSDESSTEETDKSRERSQCGVKAVNKASSTTP-KGNSSNGNSGSNSNKAVKENDK 1271
Query: 321 EPTSAGSKQNK------FPEKRKRNSVDSDL-KSTRESMIPKARESFLEKRPDGPHQKEK 373
E K+ K PE R + K R + KARE+ E+ P +KEK
Sbjct: 1272 EKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARET-KERTPKSDKEKEK 1330
Query: 374 FIKHIALK----------TPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNS 423
F K K + + KEPS E D + + N +
Sbjct: 1331 FKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKEN--------VKGG 1382
Query: 424 DQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAG 483
++ V+G+ ++ + + +P E+ ++ + + + SST K+
Sbjct: 1383 EKTPVSGSLKSPVPRSDIP-EPEREQKRRKIDTHPSPSHSSTVKD--------------- 1426
Query: 484 SSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKAD----------- 532
SL+ L + L ++ S SKE + K +E + K D
Sbjct: 1427 -SLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDH 1485
Query: 533 SNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSA 592
SN R + T PC DK ++ +SSG S
Sbjct: 1486 SNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSF 1545
Query: 593 LKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEE 626
K+ D+ S G +S ++E ++ E+
Sbjct: 1546 KSEKM------DKISSGGKKESRHDKEKIEKKEK 1573
Score = 37.0 bits (84), Expect = 0.11
Identities = 65/382 (17%), Positives = 136/382 (35%), Gaps = 38/382 (9%)
Query: 18 PGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASKQDRHMLDSPQKSNIKYG 77
PG P + S + ++ + T+ +R Q + AS +P+ ++
Sbjct: 1204 PGGGPSSSSIGSASKSDESSTEETDKSRERSQCGVKAVNKASST------TPKGNSSNGN 1257
Query: 78 GSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVKEH------HEDHGIHES 131
S ++ +++ KE + K P +P K KE ++D E+
Sbjct: 1258 SGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARET 1317
Query: 132 R---------RPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRS--PERRKSLFIH 180
+ + K + VP++ E KS +++ R P R + +
Sbjct: 1318 KERTPKSDKEKEKFKKEEKAKDEKFKTTVPNA-----ESKSTQEREREKEPSRERDIAKE 1372
Query: 181 ENNEKNDRDRGKTNADSKKQTTVAEADI----FNNSSRSLSSRSSLSRHHPEESPLGAKF 236
+++N + KT ++ V +DI R + + S S + L
Sbjct: 1373 MKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSLIELK 1432
Query: 237 QLSLASYCRERE--LKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQND 294
+ S Y L + ++ +M+++ + + S + K +RK + R +
Sbjct: 1433 ESSAKLYINHTPPPLSKSKEREMDKK-DLDKSRERSREREKKDEKDRKERKRDHSNNDRE 1491
Query: 295 IIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIP 354
+ P ENG + + S+S + ++++K K K + + S + +
Sbjct: 1492 VPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMD 1551
Query: 355 KARESFLEKRPDGPHQKEKFIK 376
K + + H KEK K
Sbjct: 1552 KISSG---GKKESRHDKEKIEK 1570
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 47.8 bits (112), Expect = 6e-05
Identities = 119/575 (20%), Positives = 220/575 (38%), Gaps = 80/575 (13%)
Query: 132 RRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHEN-NEKNDR-- 188
R P L SK +K ++ S +K+ ++ + + K FI + NE+ R
Sbjct: 247 RNPAPRLKSKKWSKKFQSFIESCL-----VKNHSQRPATEQLMKHPFIRDQPNERQVRIQ 301
Query: 189 -----DRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKF-QLSLAS 242
DR K K +T + + S S + P ES L F +L LA+
Sbjct: 302 LKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLAN 361
Query: 243 YCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPR-QEQRKQNDIIPGKNN 301
R L+R + EQ +QR N E+ + + +++ + R +EQ+++ + +
Sbjct: 362 KERSEALRRQQLEQ-QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE 420
Query: 302 LSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMI----PKAR 357
+ +R K+ + E+R+ + LK R+ ++ +
Sbjct: 421 REQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQE 480
Query: 358 ESFLEKRP-------DGPHQKEKFIKHI----ALKTPGDVLRL-EDISKEPSDETDGSSA 405
+ +EK+P P +K + K I A+K+ G L + + ++P+ G
Sbjct: 481 QRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQE 540
Query: 406 GLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASST 465
L N H Q + + P LP EK ++S L++ +
Sbjct: 541 AL------NVTSHRVEMPRQ-----NSDPTSENPPLPTRIEK--FDRSSWLRQEEDIPPK 587
Query: 466 TKEKETKL-PLLSR--VPSAGSSL------VPLNAKNCAL----PVSKKDKERSSSKECS 512
++ T + P L+R P GS+L P+ A N L P+ + +R+SS S
Sbjct: 588 VPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSS 647
Query: 513 GHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAP 572
ST S++ + G +G R+ +KS + V+P P+ P
Sbjct: 648 SSSTPSSQ--------PSSQGGSQPGSQAGSSERTRVRANSKSEGS--PVLPHEPAKVKP 697
Query: 573 SDK----APSEGESSGNS-NAGSSALKRKLRGDFDSDEES------LGYNLDSDEEEETL 621
+ PS S + + +AL ++LR + +E + Y+ S+E E +
Sbjct: 698 EESRDITRPSRPASYKKAIDEDLTALAKELR-ELRIEETNRPMKKVTDYSSSSEESESSE 756
Query: 622 KSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDY 656
+ E+ + + T A + P + G + Y
Sbjct: 757 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQY 791
>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
Length = 1844
Score = 47.4 bits (111), Expect = 8e-05
Identities = 115/581 (19%), Positives = 210/581 (36%), Gaps = 96/581 (16%)
Query: 86 TEQFERKLSSPKESKPKRVPPEKSPII-------EAFMKGVKEHHEDHGIHESRR----- 133
T +E L S KE+K + +P I E G E+ I + R
Sbjct: 264 TVSYEEFLKSHKENKVEEIPDSTMSICVPSETVDEIVKSGYISESENSEISQQVRFKTVT 323
Query: 134 ---PCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFI--HENNEKNDR 188
+ K K I++ + S + ++ ++RKS + E E
Sbjct: 324 VLAQVHPIPPKKTGKIPRIFLKQKQFEMENSLSDPENEQTVQKRKSNVVIQEEELELAVL 383
Query: 189 DRGKTNADSKKQTTVAEADIFNNSSRSLSS---RSSLSRHHPEESPLGAKFQLSLASYCR 245
+ G + A K + T+ E F + R +S ++ + + ++ L K L R
Sbjct: 384 EAGSSEA-VKPKCTLEERQQFMKAFRQPASDALKNGVKKSSDKQKDLNEK---CLYEVGR 439
Query: 246 ERELKRLRKEQMEQRINSENSFS-EASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSN 304
+ K++ + Q ++ + S +K K + ++ IPGKN N
Sbjct: 440 DDNSKKIMENSGIQMVSKNGNLQLHTDKGSFLKEKNKKLKKKNKKTLDTGAIPGKNREGN 499
Query: 305 VE-------------NGHLSRKRSSSDSWEPTSAGSKQNKFPEK------RKRNSVDSDL 345
+ +S ++ ++ ++ ++ + ++ E K +S+ ++
Sbjct: 500 TQKKETTFFLKEKQYQNRMSLRQRKTEFFKSSTLFNNESLVYEDIANDDLLKVSSLCNNN 559
Query: 346 KSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDET----- 400
K +R++ IP + + E + + TP R IS P+ ET
Sbjct: 560 KLSRKTSIPVKDIKLTQSK------AESEASLLNVSTPKSTRRSGRISSTPTTETIRGID 613
Query: 401 -----DGSSAGLAPSNSGN-SGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEK------- 447
D S + + N S HS ++ I V E+ ++ +S K
Sbjct: 614 SDDVQDNSQLKASTQKAANLSEKHSLYTAELITVPFDSESPIRMKFTRISTPKKSKKKSN 673
Query: 448 --------------SAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPL--NA 491
S I+KASN KN + + EK L +SR +PL ++
Sbjct: 674 KRSEKSEATDGGFTSQIRKASNTSKNISKAKQLIEKAKALH-ISRSKVTEEIAIPLRRSS 732
Query: 492 KNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGT 551
++ LP KK E S S + KH E K + ++V K++ T
Sbjct: 733 RHQTLPERKKLSETEDSVIIIDSSPTALKHPEKNQKKLQCLNDVLGKKLN---------T 783
Query: 552 PTKSPPAALEVVP--CIPSPAAPSDKAPSEGESSGNSNAGS 590
TK+ P ++V P + +D PS ESS +++ S
Sbjct: 784 STKNVPGKMKVAPLFLVRKAQKAADPVPSFDESSQDTSEKS 824
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 47.0 bits (110), Expect = 1e-04
Identities = 102/513 (19%), Positives = 186/513 (36%), Gaps = 57/513 (11%)
Query: 159 KEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSS 218
KE K L+KK ++RK N E+N + + + DSK+ +E + +SS
Sbjct: 561 KERKVLEKKVALSKKRKK--DSRNVEENSKKKQQYEEDSKETLKTSE----HCEKEKISS 614
Query: 219 RSSLSRHHPEESPLGAKFQLSLASYC-----RERELKRLRKEQMEQRINSENSFSEASSL 273
L H + P +LS + + E +L+R K + + E E +
Sbjct: 615 SKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTR 674
Query: 274 SLKSSIERKYKPRQEQRKQNDIIPGKNNL--SNVENGHLSR--KRSSSDSWEPTSAGSKQ 329
+K +ER +E +KQ + + +L + E HL K+ S E
Sbjct: 675 DVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEK------- 727
Query: 330 NKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGP--HQKEKFIK---HIALKTPG 384
PE+ K S D + S+ K + + K D H EK +K +I ++
Sbjct: 728 ---PEREKTPSED------KLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQ 778
Query: 385 DVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLS 444
L +D ++ S + + + + + + ++ K+ + +
Sbjct: 779 TKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKA 838
Query: 445 QEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNC-----ALPVS 499
+ KS S +QK+ S K+ + L R S +++ N V
Sbjct: 839 EHKSRRSSDSKIQKDSLGS-----KQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVV 893
Query: 500 KKDKERSSS---KECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGP---LRSEYGTPT 553
K+K R+ S ++ S T+ K+ K + + + P +E
Sbjct: 894 HKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSE 953
Query: 554 KSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSA----LKRKLRGDFDSDEESLG 609
K + +E P + P + S S ++ A K K + D DS L
Sbjct: 954 KQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLE 1013
Query: 610 YNLDSDEEEETLK-SLEEIMALNFNQTPAATGK 641
L + +LK S ++I + N++ GK
Sbjct: 1014 RKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGK 1046
Score = 35.0 bits (79), Expect = 0.42
Identities = 80/423 (18%), Positives = 154/423 (36%), Gaps = 40/423 (9%)
Query: 67 DSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVKEHHEDH 126
+ +K+ K+ S+ S + + K + KE + ++P EK+ ++G KE
Sbjct: 337 EKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKED---- 392
Query: 127 GIHESRRPCLSLASKYLAKGTNIYVPSSYHLPK----EMKSLKKKHRSPERRKSLFIHEN 182
SL + T+I V SS H E + ++ S + ++
Sbjct: 393 ---------FSLIDSDVDGLTDITV-SSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDD 442
Query: 183 NEKNDRDRGKT---NADSKKQTTVAEADI---FNNSSRSLSSRSSLSRHHPEESPLGAKF 236
EKN +++ KT ++ K +V A + + S S L+ +S K
Sbjct: 443 EEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKE 502
Query: 237 QLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPR----QEQRKQ 292
+ L +L+ RK++ E+ +S+ SS+ L+ S + +P+ +E K+
Sbjct: 503 ERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKE 562
Query: 293 NDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSD-LKSTRES 351
++ K LS K+ DS K+ ++ E K S+ + + S
Sbjct: 563 RKVLEKKVALS---------KKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKIS 613
Query: 352 MIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSN 411
+ + + P P ++ H+ + + +LE K + T G+
Sbjct: 614 SSKELKHVHAKSEPSKPARRLSESLHVVDENKNE-SKLEREHKRRT-STPVIMEGVQEET 671
Query: 412 SGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKET 471
S+ K+ K L ++ S +L K + SS K +
Sbjct: 672 DTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPERE 731
Query: 472 KLP 474
K P
Sbjct: 732 KTP 734
Score = 32.0 bits (71), Expect = 3.6
Identities = 50/255 (19%), Positives = 101/255 (39%), Gaps = 26/255 (10%)
Query: 307 NGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF------ 360
N S R+S+++ ++ K P + ++ +D + T E M K + +
Sbjct: 212 NQEASAARASTETSNAKTSERASKKLPSQPTTDT-STDKERTSEDMADKEKSTADSGGEG 270
Query: 361 LEKRP------DGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSS-AGLAPSNSG 413
LE P D P E+ IK+ + +L +D+ +E S++ + S+ G +S
Sbjct: 271 LETAPKSEEFSDLPCPVEE-IKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSN 329
Query: 414 NSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNL----QKNKTASSTTKEK 469
G ++ + K + ++++ K+ +L +KN + T +
Sbjct: 330 EKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGT 389
Query: 470 ETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERS-----SSKECSGHSTESTKHKEH 524
+ L+ + + + L ++D E S +E S + K+K++
Sbjct: 390 KEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQN 449
Query: 525 KAKTNKADSNVSSGK 539
K KT +DS S GK
Sbjct: 450 KTKTQTSDS--SEGK 462
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 46.6 bits (109), Expect = 1e-04
Identities = 72/366 (19%), Positives = 129/366 (35%), Gaps = 27/366 (7%)
Query: 258 EQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSS 317
E+ + E KS E K ++E + ++ + S + S + S
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS 566
Query: 318 DSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKH 377
E + ++ K PEK K + + KS E+ P+ +S +++ P + + +K
Sbjct: 567 PEKEEAKSPAEV-KSPEKAK-SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 378 IALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQ 437
A K+P +V E +E +P ++ + + ++ K
Sbjct: 625 EA-KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP 683
Query: 438 KPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALP 497
S EK+ + + A S KE E K P ++ P + P AK+ P
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE-EAKSPEKAKSPVKEEAKTPEKAKS---P 739
Query: 498 VSKKDKERSSSKECSGHSTESTKHKEHKAKT--------------NKADS----NVSSGK 539
V K++ +S K S ++ K +AKT KA S V S +
Sbjct: 740 V--KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 540 ISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRG 599
+ PL+ + P K P EV + P + E + K + +
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857
Query: 600 DFDSDE 605
D +E
Sbjct: 858 DSKKEE 863
Score = 42.4 bits (98), Expect = 0.003
Identities = 102/478 (21%), Positives = 180/478 (37%), Gaps = 81/478 (16%)
Query: 15 SPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFK-PASKQDRHMLDSPQKSN 73
SPA SP + A + + +SP + K + + K PA + SP K
Sbjct: 594 SPAEAKSPEK--------AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645
Query: 74 IKYGGSRLSITGTE-QFERKLSSPKESKPKRVPPEKSPII------EAFMKGVKEHHEDH 126
K S E + K SP +++ K KSP+ E VKE E
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE--EAK 703
Query: 127 GIHESRRPCLSLA-SKYLAKGTNIYVPSSYHLPKEMKS-LKKKHRSPERRKSLFIHENNE 184
+++ P A S AK V P++ KS +K++ +SPE+ KS E +
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSP---VKEEAKTPEKAKSPVKEEAKSPEKAKS---PEKAK 757
Query: 185 KNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYC 244
D + +K++ + AD F ++S +SP AK L +
Sbjct: 758 TLDVKSPEAKTPAKEEAR-SPADKFPEKAKSPVKEEV-------KSPEKAKSPLKEDAKA 809
Query: 245 RERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSN 304
E+E+ + KE++ KS ++ + KP++ + K+ P K
Sbjct: 810 PEKEIPK--KEEV------------------KSPVKEEEKPQEVKVKE----PPK----- 840
Query: 305 VENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKR 364
+ P + K +K E K+ + ++ +E + K +ES +E +
Sbjct: 841 -------KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Query: 365 PDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSD 424
+ K+K + + P V ED +P ++T+ + + + + +
Sbjct: 894 KEEAEDKKK-VPTPEKEAPAKVEVKED--AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950
Query: 425 QIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKT--------ASSTTKEKETKLP 474
+ TKE K +KP E A + L K + SS+T +K++K P
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPP 1008
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 46.6 bits (109), Expect = 1e-04
Identities = 56/268 (20%), Positives = 101/268 (37%), Gaps = 11/268 (4%)
Query: 393 SKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKK 452
S+ + + S+A + S++ +SG + NSD + T S E S
Sbjct: 108 SESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATN 167
Query: 453 ASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECS 512
+ + + AS+ T + + + SR +A +S + + + + + S+ +
Sbjct: 168 SESSTTSSGASTATNSESSTVS--SRASTATNSESSTTSSGASTATNSESRTTSNGAGTA 225
Query: 513 GHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALE-----VVPCIP 567
+S ST TN S SSG +G SE T + A V I
Sbjct: 226 TNSESSTTSSGASTATNSESSTPSSG--AGTATNSESSTTSSGAGTATNSESSTVSSGIS 283
Query: 568 SPAAPSDKAPSEGESSG-NSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEE 626
+ PS G ++ NS + +++ + DS S G + ++ E T S
Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSS-GA 342
Query: 627 IMALNFNQTPAATGKPPALSKGLRSQSS 654
A N + ++G A + G + SS
Sbjct: 343 STATNSESSTTSSGASTATNSGSSTTSS 370
Score = 36.6 bits (83), Expect = 0.14
Identities = 60/277 (21%), Positives = 94/277 (33%), Gaps = 48/277 (17%)
Query: 397 SDETDGSSAGLAPSNSGNS-----GHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIK 451
S + +++G + ++SG S G T N I T + E S +
Sbjct: 40 SGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVS 99
Query: 452 KASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKEC 511
++ N +S+T+ T S PS+G+S + SS
Sbjct: 100 SGISIATNSESSTTSSGASTATNSESSTPSSGASTA----------TNSDSSTTSSGAST 149
Query: 512 SGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAA 571
+ +S ST E TN S SSG T T S + + S A+
Sbjct: 150 ATNSDSSTTSSEASTATNSESSTTSSGA----------STATNSESST------VSSRAS 193
Query: 572 PSDKAPSEGESSGNSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEEIMALN 631
+ + S SSG S A +S +S S G ++ E T S +
Sbjct: 194 TATNSESSTTSSGASTATNS----------ESRTTSNGAGTATNSESSTTSSGASTATNS 243
Query: 632 FNQTPAATGKPPALSKGLRSQSSDYTGHVHPGTYTNT 668
+ TP++ G + S T GT TN+
Sbjct: 244 ESSTPSS-------GAGTATNSESSTTSSGAGTATNS 273
Score = 36.2 bits (82), Expect = 0.19
Identities = 49/200 (24%), Positives = 74/200 (37%), Gaps = 16/200 (8%)
Query: 400 TDGSSAGLAP---SNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNL 456
T S AG A S++ +SG + NS+ V+ T + E S +N
Sbjct: 247 TPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVT-------NSESSTPSSGANT 299
Query: 457 QKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHST 516
N +S+T+ T S S+G+S + + + SS SG ST
Sbjct: 300 ATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGAST 359
Query: 517 -----ESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAA 571
ST TN S VSSG + S T + + A + S A+
Sbjct: 360 ATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESS-TTSSGASTATNSESSTVSSGAS 418
Query: 572 PSDKAPSEGESSGNSNAGSS 591
+ + S SSG + A +S
Sbjct: 419 TATNSESSTTSSGANTATNS 438
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 46.2 bits (108), Expect = 2e-04
Identities = 103/535 (19%), Positives = 192/535 (35%), Gaps = 91/535 (17%)
Query: 258 EQRINSENSFSEASSLSLKSSIERKY------KPRQEQRKQNDIIPGKNNLSNVENGHLS 311
E +N ++S S+ S+ S E K +ND P N S+ E+ L
Sbjct: 30 EDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDE-PLNLNASDSESEELH 88
Query: 312 RKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQK 371
R++ S E + + E ++ DS+ + TR+ + L +
Sbjct: 89 RQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSEN 148
Query: 372 EKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGT 431
E KH P +E++ K P+ +++ A L P S + R+ Q + +
Sbjct: 149 EDVGKH-----PASDSEIEELQKSPASDSETEDA-LKPQISDSESEEPPRH----QASDS 198
Query: 432 KETKMQKPHLPLSQEKSAIK-KASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLN 490
+ + KP + S+ + K + S+ + + + E + R+ + S P +
Sbjct: 199 ENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRH 258
Query: 491 ----AKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLR 546
++N LP K + S E + S E K +DS S G
Sbjct: 259 QASDSENEELP---KPRISDSESEDPPRNQASDSENEELPKPRVSDSE-SEG-------- 306
Query: 547 SEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNS--------NAGSSALKRKLR 598
P K P + E P S+ E+ G ++ S ++K
Sbjct: 307 -----PQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFH 361
Query: 599 GDFDSDEESLGYNLDSD------EEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQ 652
+EE +DSD EEE+ K +++ + ++ A+ K +S S
Sbjct: 362 SSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSD 421
Query: 653 S---SDYTGHVHPGTYTNTLERLVKEMEDTQRL--------------------------- 682
S SD +G +++ E KE+ D +
Sbjct: 422 SDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESG 481
Query: 683 DELQKQL----QEDIRQGRGIKSPIRIGEEDSTDDEDGLLE-EHKEFLKKFSVTI 732
DE +++ QED+ + +G ++ E + +D +D + +H +FL F + +
Sbjct: 482 DEEEEEFTGFNQEDLEEEKG---ETQVKEAEDSDSDDNIKRGKHMDFLSDFEMML 533
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 45.8 bits (107), Expect = 2e-04
Identities = 67/329 (20%), Positives = 137/329 (41%), Gaps = 40/329 (12%)
Query: 159 KEMKSLKKKHRSPERRKSLFIH-ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLS 217
KE++ + K+ R + S I E+ + N+R G++ + ++ ++ + ++S R S
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK---SHSRRKRS 329
Query: 218 SRSSLSRHHP-----EESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASS 272
SR H ++ +K S RER R R ++R ++ E
Sbjct: 330 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 273 LSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKF 332
+ K +R+ + +E+ ++ + GKN K + + ++++
Sbjct: 390 VKEK---DREKEREREKEREKEKERGKN------------KDRDKEREKDREKDKEKDRE 434
Query: 333 PEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDI 392
E+ K + D D + +E K RE K D +K+K +TP
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK-----KSRTPPRSYNASRR 489
Query: 393 SKEPSDE---TDGSSAGLAPSNSGNSGHHSTRN-SDQIQVAGTKETKMQKPHLPLSQEK- 447
S+ S E S+ +P S S+R+ S + + K+ + ++ H+ +E+
Sbjct: 490 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549
Query: 448 --SAIKKASN----LQKNKTASSTTKEKE 470
++++K+SN +K + S++ KEKE
Sbjct: 550 RSTSMRKSSNDRDGKEKLEKNSTSLKEKE 578
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/354 (20%), Positives = 123/354 (34%), Gaps = 56/354 (15%)
Query: 24 RCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASKQDRHMLDSPQKSNIKYGGSRLSI 83
R H R S + + + R + + +S + ++DR SP K K R S
Sbjct: 309 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 368
Query: 84 TGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYL 143
+ + +++ + ++ K K EK E + +E ++ G ++ R
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR----------- 417
Query: 144 AKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTV 203
K+ + K+K R ER K E+ + D+++ K K++
Sbjct: 418 ----------DKEREKDREKDKEKDREREREK-----EHEKDRDKEKEKEQDKEKEREKD 462
Query: 204 AEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINS 263
+I + SR+ P S + S S RE +R R +
Sbjct: 463 RSKEIDEKRKKDKKSRT------PPRS-----YNASRRSRSSSRERRRRR--------SR 503
Query: 264 ENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPT 323
+S S +S ++K R PR + K+ E H+S +R S T
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSPRSRNK--------KDKKREKERDHISERRERERS---T 552
Query: 324 SAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKH 377
S N K K + LK + P + S D P +E I+H
Sbjct: 553 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQH 606
Score = 38.9 bits (89), Expect = 0.029
Identities = 66/325 (20%), Positives = 117/325 (36%), Gaps = 36/325 (11%)
Query: 227 PEESPLGAKFQLSLASYCRERELKRLRKEQ------MEQRINSENSFSEASSLSLKSSIE 280
PE +P A +L E +KR+R+ Q +E N S S S
Sbjct: 264 PEMTPQAAAKEL-------EEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKS 316
Query: 281 RKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNS 340
R +RK++ + S N SR++ S P SK + + R R+
Sbjct: 317 RSSSKSHSRRKRSQ----SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372
Query: 341 VDSDLKSTRESMIPKAR--ESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSD 398
K TRE + K R E EK + ++EK K D R +D K+
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREK-EKERGKNKDRDKEREKDREKDKEK 431
Query: 399 ETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQK 458
+ + H R+ ++ + ++ + + + +++ KK+ +
Sbjct: 432 DRE---------REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 482
Query: 459 NKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTE- 517
+ AS ++ + R S SS P +K S+ RS +K+ E
Sbjct: 483 SYNASRRSRSSSRE---RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKER 539
Query: 518 ---STKHKEHKAKTNKADSNVSSGK 539
S + + ++ + + SN GK
Sbjct: 540 DHISERRERERSTSMRKSSNDRDGK 564
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 45.8 bits (107), Expect = 2e-04
Identities = 67/329 (20%), Positives = 137/329 (41%), Gaps = 40/329 (12%)
Query: 159 KEMKSLKKKHRSPERRKSLFIH-ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLS 217
KE++ + K+ R + S I E+ + N+R G++ + ++ ++ + ++S R S
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK---SHSRRKRS 213
Query: 218 SRSSLSRHHP-----EESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASS 272
SR H ++ +K S RER R R ++R ++ E
Sbjct: 214 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 273 LSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKF 332
+ K +R+ + +E+ ++ + GKN K + + ++++
Sbjct: 274 VKEK---DREKEREREKEREKEKERGKN------------KDRDKEREKDREKDKEKDRE 318
Query: 333 PEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDI 392
E+ K + D D + +E K RE K D +K+K +TP
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK-----KSRTPPRSYNASRR 373
Query: 393 SKEPSDE---TDGSSAGLAPSNSGNSGHHSTRN-SDQIQVAGTKETKMQKPHLPLSQEK- 447
S+ S E S+ +P S S+R+ S + + K+ + ++ H+ +E+
Sbjct: 374 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433
Query: 448 --SAIKKASN----LQKNKTASSTTKEKE 470
++++K+SN +K + S++ KEKE
Sbjct: 434 RSTSMRKSSNDRDGKEKLEKNSTSLKEKE 462
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/354 (20%), Positives = 123/354 (34%), Gaps = 56/354 (15%)
Query: 24 RCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASKQDRHMLDSPQKSNIKYGGSRLSI 83
R H R S + + + R + + +S + ++DR SP K K R S
Sbjct: 193 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 252
Query: 84 TGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYL 143
+ + +++ + ++ K K EK E + +E ++ G ++ R
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR----------- 301
Query: 144 AKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTV 203
K+ + K+K R ER K E+ + D+++ K K++
Sbjct: 302 ----------DKEREKDREKDKEKDREREREK-----EHEKDRDKEKEKEQDKEKEREKD 346
Query: 204 AEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINS 263
+I + SR+ P S + S S RE +R R +
Sbjct: 347 RSKEIDEKRKKDKKSRT------PPRS-----YNASRRSRSSSRERRRRR--------SR 387
Query: 264 ENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPT 323
+S S +S ++K R PR + K+ E H+S +R S T
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSPRSRNK--------KDKKREKERDHISERRERERS---T 436
Query: 324 SAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKH 377
S N K K + LK + P + S D P +E I+H
Sbjct: 437 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQH 490
Score = 38.9 bits (89), Expect = 0.029
Identities = 66/325 (20%), Positives = 117/325 (36%), Gaps = 36/325 (11%)
Query: 227 PEESPLGAKFQLSLASYCRERELKRLRKEQ------MEQRINSENSFSEASSLSLKSSIE 280
PE +P A +L E +KR+R+ Q +E N S S S
Sbjct: 148 PEMTPQAAAKEL-------EEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKS 200
Query: 281 RKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNS 340
R +RK++ + S N SR++ S P SK + + R R+
Sbjct: 201 RSSSKSHSRRKRSQ----SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256
Query: 341 VDSDLKSTRESMIPKAR--ESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSD 398
K TRE + K R E EK + ++EK K D R +D K+
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREK-EKERGKNKDRDKEREKDREKDKEK 315
Query: 399 ETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQK 458
+ + H R+ ++ + ++ + + + +++ KK+ +
Sbjct: 316 DRE---------REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 366
Query: 459 NKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTE- 517
+ AS ++ + R S SS P +K S+ RS +K+ E
Sbjct: 367 SYNASRRSRSSSRE---RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKER 423
Query: 518 ---STKHKEHKAKTNKADSNVSSGK 539
S + + ++ + + SN GK
Sbjct: 424 DHISERRERERSTSMRKSSNDRDGK 448
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 45.4 bits (106), Expect = 3e-04
Identities = 74/330 (22%), Positives = 123/330 (37%), Gaps = 52/330 (15%)
Query: 188 RDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEE-SPLGAKFQLSLASYCRE 246
RDR ++ + +K + + RS S + +R H SP A+ + S +E
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 247 RELKRL---RKEQMEQRINS---ENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 300
R+ +L KE+ +R S E ++ S S + R P +E++++ P K
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 301 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEK-RKRNSVDSDLKSTRESMIPKARES 359
S+ RS S+ E +Q++ P K R R S K + E
Sbjct: 543 R-------DRSQSRSPSEERE-----HRQSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590
Query: 360 FLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHS 419
R P+++ + + A S + S PS GN H
Sbjct: 591 RDHSRSRSPNKQSGYSRPRA-----------------SSKEKAHSRSRTPSKEGN--HSQ 631
Query: 420 TRNSDQIQVAGTKETKMQKPHLPLSQE-KSAIKKASNLQKNKTASSTTKEKETKLPLLSR 478
+R S +KE+ + +P S + K + + S+L +N+T S T+ + P +
Sbjct: 632 SRTS-------SKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQ 684
Query: 479 VPSAGSSLVPLNAKNCALPVSKKDKERSSS 508
S S LP ERSSS
Sbjct: 685 TLSQDDSQADATTSKATLP-----GERSSS 709
Score = 34.3 bits (77), Expect = 0.72
Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 5/179 (2%)
Query: 166 KKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRH 225
++ RSP + + ++ K +RD ++ + SK++ RS S S R
Sbjct: 498 RRSRSPSKERQCRQSRSSSK-ERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE 556
Query: 226 HPE-ESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLS--LKSSIERK 282
H + SP + + S +ERE ++ R E+ + S ++ S S SS E+
Sbjct: 557 HRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA 616
Query: 283 YKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGS-KQNKFPEKRKRNS 340
+ + K+ + + + + + RS PT S QN+ P K +S
Sbjct: 617 HSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 45.4 bits (106), Expect = 3e-04
Identities = 91/419 (21%), Positives = 156/419 (37%), Gaps = 82/419 (19%)
Query: 157 LPKEMKSLKK---KHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAE-------- 205
+ KE K+LKK KH+ E+ K H+ + ++++ KT +K+ E
Sbjct: 620 MDKEGKTLKKHKLKHKEREKEK----HKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKE 675
Query: 206 --------ADIFNN---SSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRK 254
D+F N S +L +S L ++ ++ K ++ ER+ +++K
Sbjct: 676 NFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERD--KIKK 733
Query: 255 EQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKR 314
E SE SF E LK ER+ P + + + G + + HL K
Sbjct: 734 E-------SEKSFREEKIKDLKE--ERENIPTDKDSEFTSL--GMSAIEESIGLHLVEKE 782
Query: 315 SSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKF 374
+ E SK+ PEKR + +E +EK +KEK
Sbjct: 783 IDIEKQEKHIKESKEK--PEKRSQ-----------------IKEKDIEKMERKTFEKEKK 823
Query: 375 IKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST----------RNSD 424
IKH K+ D L L + + ++ S + +T ++ +
Sbjct: 824 IKH-EHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSRE 882
Query: 425 QIQVAGTKETKMQKPHLPLSQEKSAI----KKASNLQKNKTASSTTKEKETKLPLLSRVP 480
++ KE ++ HL S+EK + K++ N + +K+ KEK+ +L +
Sbjct: 883 KMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSR 942
Query: 481 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGK 539
S +N N SK +E S G+ + K K KT GK
Sbjct: 943 DKES----INITN-----SKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGK 992
Score = 40.0 bits (92), Expect = 0.013
Identities = 97/450 (21%), Positives = 175/450 (38%), Gaps = 57/450 (12%)
Query: 264 ENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPT 323
E F + + I+ ++ R+EQRK+N+ E HL K+ ++ P
Sbjct: 337 EYEFKDDDDEEINKMIDDRHILRKEQRKENE--------PEAEKTHLFAKQEK--AFYPK 386
Query: 324 SAGSKQNK-------FPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPD----GPHQKE 372
S SK+ K E ++ + ST S+IP+ S ++ + + G H+++
Sbjct: 387 SFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQK 446
Query: 373 KFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTK 432
+K LK +++ +E + + L N+G TR + + +
Sbjct: 447 GKVKR-KLKNQNKNKENQELKQEKEGKENTRITNLT-VNTGLDCSEKTREEGNFRKSFSP 504
Query: 433 ETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAK 492
+ +S KS K + L + + S+ K++ TK L S GSS + L
Sbjct: 505 KDDTSLHLFHISTGKSP-KHSCGLSEKQ--STPLKQEHTKTCL-----SPGSSEMSLQPD 556
Query: 493 NCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTP 552
++ + SS S +S KHKE K+K K D ++ G+ S ++ E +P
Sbjct: 557 LVRYDNTESEFLPESS------SVKSCKHKE-KSKHQK-DFHLEFGEKSNAKIKDEDHSP 608
Query: 553 TKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGDFD-----SDEES 607
T E C K + + + K+++ G+ + +
Sbjct: 609 T------FENSDCTLKKMDKEGKTLKKHKLK-HKEREKEKHKKEIEGEKEKYKTKDSAKE 661
Query: 608 LGYNLDSDEE---EETLKSLE-EIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV-HP 662
L +++ D E E KS E E + LN K L K ++ S HV
Sbjct: 662 LQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKE 721
Query: 663 GTYTNTLERLVKEMEDTQRLDELQKQLQED 692
+ +++ KE E + R +E K L+E+
Sbjct: 722 RNFKEERDKIKKESEKSFR-EEKIKDLKEE 750
Score = 34.3 bits (77), Expect = 0.72
Identities = 101/475 (21%), Positives = 168/475 (35%), Gaps = 59/475 (12%)
Query: 91 RKLSSPKESKPKR---VPPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLAKGT 147
RK SPK+ + KSP G+ E E + CLS S ++
Sbjct: 499 RKSFSPKDDTSLHLFHISTGKSPKHSC---GLSEKQSTPLKQEHTKTCLSPGSSEMSLQP 555
Query: 148 NIYV---PSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKN-----DRDRGKTNADSKK 199
++ S LP+ KH+ + + F E EK+ D D T +S
Sbjct: 556 DLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDC 615
Query: 200 QTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQ 259
+ + L + H +E G K + +E + R + ++
Sbjct: 616 TLKKMDKEGKTLKKHKLKHKEREKEKHKKEIE-GEKEKYKTKDSAKELQ----RSVEFDR 670
Query: 260 RINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDS 319
EN F + L ++E + +++ K I K++ S E H+S++R+ +
Sbjct: 671 EFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI--KDDKSTKEK-HVSKERNFKEE 727
Query: 320 WEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIA 379
+ K K EK R DLK RE+ IP ++S E G E+ I
Sbjct: 728 RD------KIKKESEKSFREEKIKDLKEEREN-IPTDKDS--EFTSLGMSAIEESIGLHL 778
Query: 380 LKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKP 439
++ D+ + E KE ++ + S + + + +I+ E K +K
Sbjct: 779 VEKEIDIEKQEKHIKESKEKPEKRSQ-IKEKDIEKMERKTFEKEKKIK----HEHKSEKD 833
Query: 440 HLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVS 499
L LS+ IK+ L + T KE E +KN A
Sbjct: 834 KLDLSECVDKIKEKDKLYSHHT-EKCHKEGE-------------------KSKNTAAIKK 873
Query: 500 KKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTK 554
D+E+S K H E + + H A++ + K S SEY K
Sbjct: 874 TDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSD---NSEYSKSEK 925
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 45.4 bits (106), Expect = 3e-04
Identities = 91/419 (21%), Positives = 156/419 (37%), Gaps = 82/419 (19%)
Query: 157 LPKEMKSLKK---KHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAE-------- 205
+ KE K+LKK KH+ E+ K H+ + ++++ KT +K+ E
Sbjct: 643 MDKEGKTLKKHKLKHKEREKEK----HKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKE 698
Query: 206 --------ADIFNN---SSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRK 254
D+F N S +L +S L ++ ++ K ++ ER+ +++K
Sbjct: 699 NFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERD--KIKK 756
Query: 255 EQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKR 314
E SE SF E LK ER+ P + + + G + + HL K
Sbjct: 757 E-------SEKSFREEKIKDLKE--ERENIPTDKDSEFTSL--GMSAIEESIGLHLVEKE 805
Query: 315 SSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKF 374
+ E SK+ PEKR + +E +EK +KEK
Sbjct: 806 IDIEKQEKHIKESKEK--PEKRSQ-----------------IKEKDIEKMERKTFEKEKK 846
Query: 375 IKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST----------RNSD 424
IKH K+ D L L + + ++ S + +T ++ +
Sbjct: 847 IKH-EHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSRE 905
Query: 425 QIQVAGTKETKMQKPHLPLSQEKSAI----KKASNLQKNKTASSTTKEKETKLPLLSRVP 480
++ KE ++ HL S+EK + K++ N + +K+ KEK+ +L +
Sbjct: 906 KMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSR 965
Query: 481 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGK 539
S +N N SK +E S G+ + K K KT GK
Sbjct: 966 DKES----INITN-----SKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGK 1015
Score = 40.0 bits (92), Expect = 0.013
Identities = 97/450 (21%), Positives = 175/450 (38%), Gaps = 57/450 (12%)
Query: 264 ENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPT 323
E F + + I+ ++ R+EQRK+N+ E HL K+ ++ P
Sbjct: 360 EYEFKDDDDEEINKMIDDRHILRKEQRKENE--------PEAEKTHLFAKQEK--AFYPK 409
Query: 324 SAGSKQNK-------FPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPD----GPHQKE 372
S SK+ K E ++ + ST S+IP+ S ++ + + G H+++
Sbjct: 410 SFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQK 469
Query: 373 KFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTK 432
+K LK +++ +E + + L N+G TR + + +
Sbjct: 470 GKVKR-KLKNQNKNKENQELKQEKEGKENTRITNLT-VNTGLDCSEKTREEGNFRKSFSP 527
Query: 433 ETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAK 492
+ +S KS K + L + + S+ K++ TK L S GSS + L
Sbjct: 528 KDDTSLHLFHISTGKSP-KHSCGLSEKQ--STPLKQEHTKTCL-----SPGSSEMSLQPD 579
Query: 493 NCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTP 552
++ + SS S +S KHKE K+K K D ++ G+ S ++ E +P
Sbjct: 580 LVRYDNTESEFLPESS------SVKSCKHKE-KSKHQK-DFHLEFGEKSNAKIKDEDHSP 631
Query: 553 TKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGDFD-----SDEES 607
T E C K + + + K+++ G+ + +
Sbjct: 632 T------FENSDCTLKKMDKEGKTLKKHKLK-HKEREKEKHKKEIEGEKEKYKTKDSAKE 684
Query: 608 LGYNLDSDEE---EETLKSLE-EIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV-HP 662
L +++ D E E KS E E + LN K L K ++ S HV
Sbjct: 685 LQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKE 744
Query: 663 GTYTNTLERLVKEMEDTQRLDELQKQLQED 692
+ +++ KE E + R +E K L+E+
Sbjct: 745 RNFKEERDKIKKESEKSFR-EEKIKDLKEE 773
Score = 34.3 bits (77), Expect = 0.72
Identities = 101/475 (21%), Positives = 168/475 (35%), Gaps = 59/475 (12%)
Query: 91 RKLSSPKESKPKR---VPPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLAKGT 147
RK SPK+ + KSP G+ E E + CLS S ++
Sbjct: 522 RKSFSPKDDTSLHLFHISTGKSPKHSC---GLSEKQSTPLKQEHTKTCLSPGSSEMSLQP 578
Query: 148 NIYV---PSSYHLPKEMKSLKKKHRSPERRKSLFIHENNEKN-----DRDRGKTNADSKK 199
++ S LP+ KH+ + + F E EK+ D D T +S
Sbjct: 579 DLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDC 638
Query: 200 QTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQ 259
+ + L + H +E G K + +E + R + ++
Sbjct: 639 TLKKMDKEGKTLKKHKLKHKEREKEKHKKEIE-GEKEKYKTKDSAKELQ----RSVEFDR 693
Query: 260 RINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDS 319
EN F + L ++E + +++ K I K++ S E H+S++R+ +
Sbjct: 694 EFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI--KDDKSTKEK-HVSKERNFKEE 750
Query: 320 WEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIA 379
+ K K EK R DLK RE+ IP ++S E G E+ I
Sbjct: 751 RD------KIKKESEKSFREEKIKDLKEEREN-IPTDKDS--EFTSLGMSAIEESIGLHL 801
Query: 380 LKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKP 439
++ D+ + E KE ++ + S + + + +I+ E K +K
Sbjct: 802 VEKEIDIEKQEKHIKESKEKPEKRSQ-IKEKDIEKMERKTFEKEKKIK----HEHKSEKD 856
Query: 440 HLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVS 499
L LS+ IK+ L + T KE E +KN A
Sbjct: 857 KLDLSECVDKIKEKDKLYSHHT-EKCHKEGE-------------------KSKNTAAIKK 896
Query: 500 KKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTK 554
D+E+S K H E + + H A++ + K S SEY K
Sbjct: 897 TDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSD---NSEYSKSEK 948
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,599,731
Number of Sequences: 37866
Number of extensions: 2353998
Number of successful extensions: 11858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 507
Number of HSP's that attempted gapping in prelim test: 10516
Number of HSP's gapped (non-prelim): 1636
length of query: 1173
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1060
effective length of database: 13,968,660
effective search space: 14806779600
effective search space used: 14806779600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.