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Search of human proteins with 150417981
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
(1499 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 3010 0.0
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 1469 0.0
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 1465 0.0
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 136 2e-31
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 136 2e-31
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 126 2e-28
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 126 2e-28
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 126 2e-28
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 126 2e-28
gi|188497642 ARHGAP15 [Homo sapiens] 122 3e-27
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 122 3e-27
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 118 4e-26
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 114 9e-25
gi|4505507 oligophrenin 1 [Homo sapiens] 112 4e-24
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 111 5e-24
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s... 107 7e-23
gi|229094128 active breakpoint cluster region-related protein i... 105 3e-22
gi|38679957 active breakpoint cluster region-related protein is... 105 3e-22
gi|38679954 active breakpoint cluster region-related protein is... 105 3e-22
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 104 6e-22
gi|208022687 GTPase regulator associated with the focal adhesion... 104 7e-22
gi|7662208 GTPase regulator associated with the focal adhesion k... 104 7e-22
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 103 1e-21
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 103 1e-21
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 103 1e-21
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 103 1e-21
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 101 5e-21
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 101 6e-21
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 101 6e-21
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 100 1e-20
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 3010 bits (7803), Expect = 0.0
Identities = 1499/1499 (100%), Positives = 1499/1499 (100%)
Query: 1 MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLST 60
MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLST
Sbjct: 1 MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLST 60
Query: 61 SDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRA 120
SDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRA
Sbjct: 61 SDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRA 120
Query: 121 AATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKF 180
AATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKF
Sbjct: 121 AATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKF 180
Query: 181 VSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSKKNLQVVETSARSNVNVDLAF 240
VSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSKKNLQVVETSARSNVNVDLAF
Sbjct: 181 VSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSKKNLQVVETSARSNVNVDLAF 240
Query: 241 STLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQ 300
STLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQ
Sbjct: 241 STLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQ 300
Query: 301 ASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDH 360
ASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDH
Sbjct: 301 ASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDH 360
Query: 361 LSCIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENERIPFDLMDTVPAEQLYEAHL 420
LSCIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENERIPFDLMDTVPAEQLYEAHL
Sbjct: 361 LSCIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENERIPFDLMDTVPAEQLYEAHL 420
Query: 421 EKLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKH 480
EKLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKH
Sbjct: 421 EKLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKH 480
Query: 481 QKQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAER 540
QKQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAER
Sbjct: 481 QKQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAER 540
Query: 541 DALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIRPSDRNQKNSLSDPNIDRINL 600
DALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIRPSDRNQKNSLSDPNIDRINL
Sbjct: 541 DALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIRPSDRNQKNSLSDPNIDRINL 600
Query: 601 VILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHG 660
VILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHG
Sbjct: 601 VILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHG 660
Query: 661 CLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQ 720
CLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQ
Sbjct: 661 CLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQ 720
Query: 721 GQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSSTASIKDLADV 780
GQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSSTASIKDLADV
Sbjct: 721 GQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSSTASIKDLADV 780
Query: 781 DLRIVMCLMCGDPFSADDILFPVLQSQTCKSSHCGSNNSVLLELPIGLHKKRIELSVLSY 840
DLRIVMCLMCGDPFSADDILFPVLQSQTCKSSHCGSNNSVLLELPIGLHKKRIELSVLSY
Sbjct: 781 DLRIVMCLMCGDPFSADDILFPVLQSQTCKSSHCGSNNSVLLELPIGLHKKRIELSVLSY 840
Query: 841 HSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAVDVLDNDL 900
HSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAVDVLDNDL
Sbjct: 841 HSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAVDVLDNDL 900
Query: 901 SREQLTEGEEIAQEIDGRFTSIPCSQPQHKLEIFHPFFKDVVEKKNIIEATHMYDNAAEA 960
SREQLTEGEEIAQEIDGRFTSIPCSQPQHKLEIFHPFFKDVVEKKNIIEATHMYDNAAEA
Sbjct: 901 SREQLTEGEEIAQEIDGRFTSIPCSQPQHKLEIFHPFFKDVVEKKNIIEATHMYDNAAEA 960
Query: 961 CSTTEEVFNSPRAGSPLCNSNLQDSEEDIEPSYSLFREDTSLPSLSKDHSKLSMELEGND 1020
CSTTEEVFNSPRAGSPLCNSNLQDSEEDIEPSYSLFREDTSLPSLSKDHSKLSMELEGND
Sbjct: 961 CSTTEEVFNSPRAGSPLCNSNLQDSEEDIEPSYSLFREDTSLPSLSKDHSKLSMELEGND 1020
Query: 1021 GLSFIMSNFESKLNNKVPPPVKPKPPVHFEITKGDLSYLDQGHRDGQRKSVSSSPWLPQD 1080
GLSFIMSNFESKLNNKVPPPVKPKPPVHFEITKGDLSYLDQGHRDGQRKSVSSSPWLPQD
Sbjct: 1021 GLSFIMSNFESKLNNKVPPPVKPKPPVHFEITKGDLSYLDQGHRDGQRKSVSSSPWLPQD 1080
Query: 1081 GFDPSDYAEPMDAVVKPRNEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDT 1140
GFDPSDYAEPMDAVVKPRNEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDT
Sbjct: 1081 GFDPSDYAEPMDAVVKPRNEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDT 1140
Query: 1141 SSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGYKG 1200
SSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGYKG
Sbjct: 1141 SSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGYKG 1200
Query: 1201 DNAVIPYETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKP 1260
DNAVIPYETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKP
Sbjct: 1201 DNAVIPYETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKP 1260
Query: 1261 IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGA 1320
IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGA
Sbjct: 1261 IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGA 1320
Query: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN
Sbjct: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
Query: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP
Sbjct: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
Query: 1441 ITEPPGARPSSPSAVASTVPFLTSTPVTSQPSPPQSPPPTPQSPMQPLLPSQLQAEHTL 1499
ITEPPGARPSSPSAVASTVPFLTSTPVTSQPSPPQSPPPTPQSPMQPLLPSQLQAEHTL
Sbjct: 1441 ITEPPGARPSSPSAVASTVPFLTSTPVTSQPSPPQSPPPTPQSPMQPLLPSQLQAEHTL 1499
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 1469 bits (3803), Expect = 0.0
Identities = 770/1527 (50%), Positives = 1044/1527 (68%), Gaps = 63/1527 (4%)
Query: 2 MMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTS 61
MMA+ ++ R P+Y IS+VGLSGTEK+KG CG+GKSCLCNRFVR ADE++ +HTSVLST
Sbjct: 1 MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI 60
Query: 62 DFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAA 121
DFGGRVVNNDHFLYWG++ ++ ED VECK+H++EQTEFIDDQTF PHRST LQPYIKRAA
Sbjct: 61 DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA 120
Query: 122 ATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFV 181
A+KL SAEKLMY CTDQLGLEQDFEQKQMP+GKL VDGFLL IDVS+G NR FDDQLKFV
Sbjct: 121 ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV 180
Query: 182 SNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSKKNLQVVETSARSNVNVDLAFS 241
+NL+ QL+K+KKP+++ TKCDE V+ Y+R+ FA +KKNL VVETSAR NVN++ F+
Sbjct: 181 NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT 240
Query: 242 TLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQA 301
LVQ++DK+R K KIIPY +A K Q Q + TA DK+E LV + V++++ W +VS K++
Sbjct: 241 ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLV-QTVRDYHATWKTVSNKLKN 299
Query: 302 SPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDHL 361
P+Y++Y+ LEGT+KA+ F +HI +LK EHI +RR+ Y+ LP AF L+PNL+EI+HL
Sbjct: 300 HPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHL 359
Query: 362 SCIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENERIPFDLMDTVPAEQLYEAHLE 421
+ +A KL+E + +F FVVLE+TPWD T HID + + RIPFDL+ T+ AE++Y+ H++
Sbjct: 360 NWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQ 419
Query: 422 KLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQ 481
L +E++RVEM+ FK+ LE FI+PG+PWEE F+M ++ Y+++ E+ ++YG+HQ
Sbjct: 420 HLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQ 479
Query: 482 KQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERD 541
++I++KAKEEFQE+L E+SELFY+L+L+A PS +KM I VL EE R+KALQKL +R+
Sbjct: 480 REIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRE 539
Query: 542 ALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIRPSDRNQKNSLSDPNIDRINLV 601
+L+LKHI FVYHPTKETC S C D K+E L++S ++ + NID++NL
Sbjct: 540 SLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLF 599
Query: 602 ILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGC 661
ILGKDGLA+ELANEIR T DD+Y +DGK+YEL LRP++ ++ T F+PHGC
Sbjct: 600 ILGKDGLAQELANEIRTQST-DDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGC 658
Query: 662 LCLYNSKESLSYVVESIEKSR-ESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQ 720
C++NS ESLS++ E I K R E++ R+D ++ +LP TLIL N+R D+ + L L Q
Sbjct: 659 FCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQR-DSISKNLPILRHQ 717
Query: 721 GQQIASKLQCVFLD-PASAGIGYGRNINEKQISQVLKGLLDS-KRNLNLVSSTASIKDLA 778
GQQ+A+KLQC F+D PA Y R NE QI Q L+G+L+S K NL++VS + KDL+
Sbjct: 718 GQQLANKLQCPFVDVPAGT---YPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLS 774
Query: 779 DVDLRIVMCLMCGDPFSADDILFPVLQSQTCKSSHCGSNNSVLLELPIGLHKKRIELSVL 838
+ DLRIVMC MCGDPFS D IL P L S +C ++ G NNS++L+ IG ++RI++++L
Sbjct: 775 EADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITIL 834
Query: 839 SYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAVDVLDN 898
SYHSS +RK LVHGYI+ YSAKRKAS+ MLRAFL EVQD IP+QLVA+TD D +N
Sbjct: 835 SYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFEN 894
Query: 899 DLSREQLTEGEEIAQEIDGRFTSI-PCSQPQHKLEIFHPFFKDVVEKKNIIEATHMYDNA 957
+ +E +TEGE IA EI +FT++ SQ + E+F FF DV+EKKN+IE +++ DN
Sbjct: 895 EAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNT 954
Query: 958 AEACSTTEEVF-NSPRAGSPLCNSNLQDSEEDIE--PSYSLFREDTSLPSLSKDHSKLSM 1014
E+ +E+VF SPR P +N DS++D E P YS +D L D S+ +
Sbjct: 955 RESTHQSEDVFLPSPRDCFPY--NNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRL 1012
Query: 1015 ELEGNDGLSFIMSN-FESKLNNKVPPPVKPKPPV-HFEITKGD---LSYLDQGHRDGQRK 1069
+LEGN+ N + + N+KVPPP+KPKP V + K D L ++ G RK
Sbjct: 1013 DLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRK 1072
Query: 1070 SVSSSPWLPQDGFDPSD-YAEPMDAVVKPRNEEENIYSVPHDSTQGKIITIRN--INKAQ 1126
S P + DPSD YAEP+D + K + + IY VP DS I IRN +N Q
Sbjct: 1073 QTSRVPLAHPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNR--IKIRNSFVNNTQ 1130
Query: 1127 SNGSGNGSDSEMDTSSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPI 1186
+ SD + R K SK + + + + YR + S SDDE
Sbjct: 1131 GDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAK-------SYYRRTHSDASDDEAFTT 1183
Query: 1187 RKKEEDQASQGYKGDNAVIPYET---------------DEDPRRRNILRSLRRNTKKPKP 1231
K + +G + D + P ET +D + + ++ + KK K
Sbjct: 1184 SKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKT 1243
Query: 1232 KPRPSITKATWESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSE 1291
K T+ WESNYFG+PL +VT EKPIP+F+E+C+E+IE TGL TEG+YRVSGNK++
Sbjct: 1244 KNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTD 1303
Query: 1292 MESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDRE 1351
+++Q+QFDQDHN++L + TVN VAGA+K+FF++LPDPL+PY++ +L+EA KI D+
Sbjct: 1304 QDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKT 1363
Query: 1352 QKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFST 1411
++LHALKE++KKF N++VF+YVI+HLN+VS +K+NLMT++NLSICFWPTLMRPDF
Sbjct: 1364 ERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFEN 1423
Query: 1412 MDALTATRTYQTIIELFIQQCPFFFYNRPITEPPG-ARPSSPSAVASTVPFLTSTPVTSQ 1470
+ L+ T+ +Q+++E FIQQC FFFYN I E P PS V +
Sbjct: 1424 REFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLV----------E 1473
Query: 1471 PSPPQSPPPTPQSPMQP-LLPSQLQAE 1496
P P PP P+QP L+ QLQ +
Sbjct: 1474 PMVPLQLPP----PLQPQLIQPQLQTD 1496
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 1465 bits (3793), Expect = 0.0
Identities = 769/1528 (50%), Positives = 1042/1528 (68%), Gaps = 64/1528 (4%)
Query: 2 MMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTS 61
MMA+ ++ R P+Y IS+VGLSGTEK+KG CG+GKSCLCNRFVR ADE++ +HTSVLST
Sbjct: 1 MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI 60
Query: 62 DFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAA 121
DFGGRVVNNDHFLYWG++ ++ ED VECK+H++EQTEFIDDQTF PHRST LQPYIKRAA
Sbjct: 61 DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA 120
Query: 122 ATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFV 181
A+KL SAEKLMY CTDQLGLEQDFEQKQMP+GKL VDGFLL IDVS+G NR FDDQLKFV
Sbjct: 121 ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV 180
Query: 182 SNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSKKNLQVVETSARSNVNVDLAFS 241
+NL+ QL+K+KKP+++ TKCDE V+ Y+R+ FA +KKNL VVETSAR NVN++ F+
Sbjct: 181 NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT 240
Query: 242 TLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQA 301
LVQ++DK+R K KIIPY +A K Q Q + TA DK+E LV + V++++ W +VS K++
Sbjct: 241 ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLV-QTVRDYHATWKTVSNKLKN 299
Query: 302 SPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDHL 361
P+Y++Y+ LEGT+KA+ F +HI +LK EHI +RR+ Y+ LP AF L+PNL+EI+HL
Sbjct: 300 HPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHL 359
Query: 362 SCIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENERIPFDLMDTVPAEQLYEAHLE 421
+ +A KL+E + +F FVVLE+TPWD T HID + + RIPFDL+ T+ AE++Y+ H++
Sbjct: 360 NWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQ 419
Query: 422 KLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQ 481
L +E++RVEM+ FK+ LE FI+PG+PWEE F+M ++ Y+++ E+ ++YG+HQ
Sbjct: 420 HLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQ 479
Query: 482 KQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERD 541
++I++KAKEEFQE+L E+SELFY+L+L+A PS +KM I VL EE R+KALQKL +R+
Sbjct: 480 REIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRE 539
Query: 542 ALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIRPSDRNQKNSLSDPNIDRINLV 601
+L+LKHI FVYHPTKETC S C D K+E L++S ++ + NID++NL
Sbjct: 540 SLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLF 599
Query: 602 ILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGC 661
ILGKDGLA+ELANEIR T DD+Y +DGK+YEL LRP++ ++ T F+PHGC
Sbjct: 600 ILGKDGLAQELANEIRTQST-DDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGC 658
Query: 662 LCLYNSKESLSYVVESIEKSR-ESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQ 720
C++NS ESLS++ E I K R E++ R+D ++ +LP TLIL N+R D+ + L L Q
Sbjct: 659 FCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQR-DSISKNLPILRHQ 717
Query: 721 GQQIASKLQCVFLD-PASAGIGYGRNINEKQISQVLKGLLDS-KRNLNLVSSTASIKDLA 778
GQQ+A+KLQC F+D PA Y R NE QI Q L+G+L+S K NL++VS + KDL+
Sbjct: 718 GQQLANKLQCPFVDVPAGT---YPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLS 774
Query: 779 DVDLRIVMCLMCGDPFSADDILFPVLQSQTCKSSHCGSNNSVLLELPIGLHKKRIELSVL 838
+ DLRIVMC MCGDPFS D IL P L S +C ++ G NNS++L+ IG ++RI++++L
Sbjct: 775 EADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITIL 834
Query: 839 SYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAVDVLDN 898
SYHSS +RK LVHGYI+ YSAKRKAS+ MLRAFL EVQD IP+QLVA+TD D +N
Sbjct: 835 SYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFEN 894
Query: 899 DLSREQLTEGEEIAQEIDGRFTSI-PCSQPQHKLEIFHPFFKDVVEKKNIIEATHMYDNA 957
+ +E +TEGE IA EI +FT++ SQ + E+F FF DV+EKKN+IE +++ DN
Sbjct: 895 EAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNT 954
Query: 958 AEACSTTEEVF-NSPRAGSPLCNSNLQDSEEDIE--PSYSLFREDTSLPSLSKDHSKLSM 1014
E+ +E+VF SPR P +N DS++D E P YS +D L D S+ +
Sbjct: 955 RESTHQSEDVFLPSPRDCFPY--NNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRL 1012
Query: 1015 ELEGNDGLSFIMSN-FESKLNNKVPPPVKPKPPV-HFEITKGD---LSYLDQGHRDGQRK 1069
+LEGN+ N + + N+KVPPP+KPKP V + K D L ++ G RK
Sbjct: 1013 DLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRK 1072
Query: 1070 SVSSSPWLPQDGFDPSD-YAEPMDAVVKPRNEEENIYSVPHDSTQGKIITIRN--INKAQ 1126
S P + DPSD YAEP+D + K + + IY VP DS I IRN +N Q
Sbjct: 1073 QTSRVPLAHPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNR--IKIRNSFVNNTQ 1130
Query: 1127 SNGSGNGSDSEMDTSSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPI 1186
+ SD + R K SK + + + + YR + S SDDE
Sbjct: 1131 GDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAK-------SYYRRTHSDASDDEAFTT 1183
Query: 1187 RKKEEDQASQGYKGDNAVIPYET----------------DEDPRRRNILRSLRRNTKKPK 1230
K + +G + D + P ET D+ ++ + +K K
Sbjct: 1184 SKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKK 1243
Query: 1231 PKPRPSITKATWESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKS 1290
K T+ WESNYFG+PL +VT EKPIP+F+E+C+E+IE TGL TEG+YRVSGNK+
Sbjct: 1244 TKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKT 1303
Query: 1291 EMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDR 1350
+ +++Q+QFDQDHN++L + TVN VAGA+K+FF++LPDPL+PY++ +L+EA KI D+
Sbjct: 1304 DQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDK 1363
Query: 1351 EQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFS 1410
++LHALKE++KKF N++VF+YVI+HLN+VS +K+NLMT++NLSICFWPTLMRPDF
Sbjct: 1364 TERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFE 1423
Query: 1411 TMDALTATRTYQTIIELFIQQCPFFFYNRPITEPPG-ARPSSPSAVASTVPFLTSTPVTS 1469
+ L+ T+ +Q+++E FIQQC FFFYN I E P PS V
Sbjct: 1424 NREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLV---------- 1473
Query: 1470 QPSPPQSPPPTPQSPMQP-LLPSQLQAE 1496
+P P PP P+QP L+ QLQ +
Sbjct: 1474 EPMVPLQLPP----PLQPQLIQPQLQTD 1497
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 136 bits (342), Expect = 2e-31
Identities = 77/262 (29%), Positives = 141/262 (53%), Gaps = 9/262 (3%)
Query: 1178 GSDDELGPIRKKEEDQASQGYKGDNAVIPYETDEDPRRRNILRSLRRNTKKPKPKPRPSI 1237
GS + LG ++KEED + E+D R + + L+R +P +
Sbjct: 263 GSSERLGSWQEKEEDARPNAAAPALGPVGLESDLSKVRHKLRKFLQR-----RPTLQSLR 317
Query: 1238 TKATWESNYFGVPLTTVVTPEKP-IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296
K + FG L + E+ +P F+++CI +EA GL +G+YR+SGN + ++ L+
Sbjct: 318 EKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLR 377
Query: 1297 RQFDQDHNLDLAEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLH 1355
+ D D LDL + + V+ + GA+K FF ELP+PL P++ + A K+ D+ ++
Sbjct: 378 YKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSR 437
Query: 1356 ALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDAL 1415
++++++ P NH+ + + HL +V + + N M+ ++++I F PTL+RP+ ++
Sbjct: 438 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE-TSM 496
Query: 1416 TATRTYQT-IIELFIQQCPFFF 1436
T +Q ++EL +QQC F
Sbjct: 497 PMTMVFQNQVVELILQQCADIF 518
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens]
Length = 548
Score = 136 bits (342), Expect = 2e-31
Identities = 77/262 (29%), Positives = 141/262 (53%), Gaps = 9/262 (3%)
Query: 1178 GSDDELGPIRKKEEDQASQGYKGDNAVIPYETDEDPRRRNILRSLRRNTKKPKPKPRPSI 1237
GS + LG ++KEED + E+D R + + L+R +P +
Sbjct: 290 GSSERLGSWQEKEEDARPNAAAPALGPVGLESDLSKVRHKLRKFLQR-----RPTLQSLR 344
Query: 1238 TKATWESNYFGVPLTTVVTPEKP-IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296
K + FG L + E+ +P F+++CI +EA GL +G+YR+SGN + ++ L+
Sbjct: 345 EKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLR 404
Query: 1297 RQFDQDHNLDLAEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLH 1355
+ D D LDL + + V+ + GA+K FF ELP+PL P++ + A K+ D+ ++
Sbjct: 405 YKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSR 464
Query: 1356 ALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDAL 1415
++++++ P NH+ + + HL +V + + N M+ ++++I F PTL+RP+ ++
Sbjct: 465 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE-TSM 523
Query: 1416 TATRTYQT-IIELFIQQCPFFF 1436
T +Q ++EL +QQC F
Sbjct: 524 PMTMVFQNQVVELILQQCADIF 545
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 126 bits (316), Expect = 2e-28
Identities = 69/184 (37%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Query: 1251 LTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HNLDLA 1308
LTT+V P+ ++ CI IEA GL +EG+YRVSG +E ++ FD+D D++
Sbjct: 279 LTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADIS 338
Query: 1309 EKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKE 1367
+ +N + GA+K +F +LP P++ Y+ ++A KI++ +++L A+ EVL P
Sbjct: 339 ANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPA 398
Query: 1368 NHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQTIIE 1426
++E +Y++ HL KV+ N K N M +ENL I F PTLMR P+ ST+ L R + I++
Sbjct: 399 HYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQ 458
Query: 1427 LFIQ 1430
+ I+
Sbjct: 459 ILIE 462
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 126 bits (316), Expect = 2e-28
Identities = 69/184 (37%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Query: 1251 LTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HNLDLA 1308
LTT+V P+ ++ CI IEA GL +EG+YRVSG +E ++ FD+D D++
Sbjct: 143 LTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADIS 202
Query: 1309 EKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKE 1367
+ +N + GA+K +F +LP P++ Y+ ++A KI++ +++L A+ EVL P
Sbjct: 203 ANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPA 262
Query: 1368 NHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQTIIE 1426
++E +Y++ HL KV+ N K N M +ENL I F PTLMR P+ ST+ L R + I++
Sbjct: 263 HYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQ 322
Query: 1427 LFIQ 1430
+ I+
Sbjct: 323 ILIE 326
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 126 bits (316), Expect = 2e-28
Identities = 71/194 (36%), Positives = 113/194 (58%), Gaps = 4/194 (2%)
Query: 1247 FGVPLTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HN 1304
+ LTT+V P+ ++ CI IE+ GL++EG+YRVSG +E ++ FD+D
Sbjct: 266 YSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEK 325
Query: 1305 LDLAEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKK 1363
D++ + +N + GA+K +F +LP PL+ Y+ +E+ KI D +++L L E LK
Sbjct: 326 ADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKL 385
Query: 1364 FPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQ 1422
P + E +Y+++HL +V+ + K NLM +ENL I F PTLMR P+ M AL R +
Sbjct: 386 LPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQR 445
Query: 1423 TIIELFIQQCPFFF 1436
++EL I+ F
Sbjct: 446 LVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 126 bits (316), Expect = 2e-28
Identities = 71/194 (36%), Positives = 113/194 (58%), Gaps = 4/194 (2%)
Query: 1247 FGVPLTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HN 1304
+ LTT+V P+ ++ CI IE+ GL++EG+YRVSG +E ++ FD+D
Sbjct: 240 YSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEK 299
Query: 1305 LDLAEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKK 1363
D++ + +N + GA+K +F +LP PL+ Y+ +E+ KI D +++L L E LK
Sbjct: 300 ADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKL 359
Query: 1364 FPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQ 1422
P + E +Y+++HL +V+ + K NLM +ENL I F PTLMR P+ M AL R +
Sbjct: 360 LPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQR 419
Query: 1423 TIIELFIQQCPFFF 1436
++EL I+ F
Sbjct: 420 LVVELLIKNEDILF 433
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 122 bits (305), Expect = 3e-27
Identities = 71/227 (31%), Positives = 118/227 (51%), Gaps = 2/227 (0%)
Query: 1207 YETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKP-IPIFI 1265
+ + D +N ++S + +P + K + FG L V E +P F+
Sbjct: 239 HHSASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFV 298
Query: 1266 ERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFT-VNTVAGAMKSF 1324
++CIE +E GL +GIYRVSGN + ++ L+ +Q+ L+L + + ++ V GA+K F
Sbjct: 299 KQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMF 358
Query: 1325 FSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSH 1384
F ELP+PL PY+ VEA K D ++ A+K +++K P N + K + HL K+
Sbjct: 359 FRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVA 418
Query: 1385 NNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQ 1431
NLM++++L I F PTL+R + T + I EL + +
Sbjct: 419 KASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLSE 465
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 122 bits (305), Expect = 3e-27
Identities = 76/226 (33%), Positives = 125/226 (55%), Gaps = 12/226 (5%)
Query: 1221 SLRRNTKKPKPK---PRPSITKATWESNY-----FGVPLTTVVTPEK-PIPIFIERCIEY 1271
S ++ TKK K RP++ +A E Y FG L + E +P F++ CIE+
Sbjct: 621 SEQKKTKKNLKKFLTRRPTL-QAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEH 679
Query: 1272 IEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFT-VNTVAGAMKSFFSELPD 1330
+E GL +GIYRVSGN + ++ L+ + D LDL + + ++ + GA+K FF ELP+
Sbjct: 680 VEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPE 739
Query: 1331 PLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNL 1390
PL +N D V A K R Q++ A+K+++++ PK N + + + HL +V N + N
Sbjct: 740 PLFTFNHFNDFVNAIKQEPR-QRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNR 798
Query: 1391 MTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFF 1436
MT ++++I F PTL++P+ T + T I+EL + + F
Sbjct: 799 MTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 118 bits (296), Expect = 4e-26
Identities = 89/297 (29%), Positives = 140/297 (47%), Gaps = 35/297 (11%)
Query: 1197 GYKGDNAVIPYETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWESNYFGVPLTTV-- 1254
G K D+A P + P NI++ K K PR FGV L
Sbjct: 780 GSKDDSAAAP----KTPWGINIIK------KNKKAAPRA-----------FGVRLEECQP 818
Query: 1255 VTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQ---DHNLDLAEKD 1311
T + +P+ + C +EA GL + GIYRV GN + + SLQ Q ++ D NL E+
Sbjct: 819 ATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQ-DERW 877
Query: 1312 FTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEV 1371
+N ++ +KSFF +LP+PL + D +EA++I D +++ L+++++ P +E
Sbjct: 878 QDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYET 937
Query: 1372 FKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTM-DALTATRTYQTIIELFIQ 1430
K+++ HL ++ +++ N M NL++ F PTL+R M D +T I+E IQ
Sbjct: 938 LKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQ 997
Query: 1431 QCPFFFYNRPITEPPGAR----PSSPSAVASTVPFLTSTPVTSQPSPPQSPPPTPQS 1483
+FF + E G R P AV + L + T P P S T S
Sbjct: 998 HSDWFFSDE---EDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDSTTCSS 1051
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 114 bits (284), Expect = 9e-25
Identities = 75/254 (29%), Positives = 128/254 (50%), Gaps = 18/254 (7%)
Query: 1206 PYETDEDPRRRNILRSLRRNTKKPKPKPR-----PSITKATWE-----SNYFGVPLTTV- 1254
P+ E+ R+ + + +T PK K PSI + T+E + FGV L
Sbjct: 1097 PHSPKEESERKLLSKD---DTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDCP 1153
Query: 1255 -VTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDH-NLDLAEKDF 1312
+ IP+ ++ C + +E GL GIYRV GN + + S+Q + ++ ++D+ + +
Sbjct: 1154 PAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKW 1213
Query: 1313 T-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEV 1371
+N ++ +KSFF +LP+PL + D +EA++ D +L LK ++ P+ ++E
Sbjct: 1214 RDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYET 1273
Query: 1372 FKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQ-TIIELFIQ 1430
K++ +HL V+ N++ N M NL+I F PTL+R M + Q I+E IQ
Sbjct: 1274 LKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQ 1333
Query: 1431 QCPFFFYNRPITEP 1444
+FF EP
Sbjct: 1334 HHDWFFTEEGAEEP 1347
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 112 bits (279), Expect = 4e-24
Identities = 70/259 (27%), Positives = 121/259 (46%), Gaps = 28/259 (10%)
Query: 1264 FIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDH---NLDLAEKDFTVNTVAGA 1320
F+ +CI IE G+ TEG+YR G+ +++ L F ++D D+ + T+ +
Sbjct: 389 FVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSS 448
Query: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
+K + L +P++ Y + +LV A K ++ + +L A+ ++ K P++N E+ + +I HL
Sbjct: 449 LKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLV 508
Query: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
V ++K NLMT N+ + F PTLMR T+ A+ + ++E+ I+ + P
Sbjct: 509 NVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPP 568
Query: 1441 ITEPPGARPSSPSAVAS----------------TVPFLTSTPVTSQPSPPQSPPPT---- 1480
E A P P V + TV + +S + Q+P T
Sbjct: 569 --EESAAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHQTPNGTITSS 626
Query: 1481 ---PQSPMQPLLPSQLQAE 1496
P+ P P LP Q E
Sbjct: 627 IEPPKPPQHPKLPIQRSGE 645
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 111 bits (278), Expect = 5e-24
Identities = 65/218 (29%), Positives = 107/218 (49%), Gaps = 23/218 (10%)
Query: 1265 IERCIEYIEATGLSTEGIYRVSGNKSEME---SLQRQFDQDHNLDLAEK-DFTVNTVAGA 1320
I +CI +E G++ +G+YRV G S+++ S+ + +DL D+ V T+ A
Sbjct: 399 IRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSA 458
Query: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
+K + LP+PL+ Y + D + K E +++A+ ++ K P++N E+ ++ HL
Sbjct: 459 LKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLT 518
Query: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
VS+++K NLMT NL + F PTLMRP T+ AL + ++E+ I+ F P
Sbjct: 519 NVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPP 578
Query: 1441 ITEPPGARPSSPSAVASTVPFLTSTPVTSQPSPPQSPP 1478
T P P SPP +PP
Sbjct: 579 DTTFP-------------------EPTCLSASPPNAPP 597
Score = 32.3 bits (72), Expect = 3.5
Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 5/51 (9%)
Query: 1350 REQKLHALKEVLKKFPKENHEVFKYVISHLN-----KVSHNNKVNLMTSEN 1395
R+++L A+KE KKF KE + + + HLN K SH + ++ +N
Sbjct: 120 RKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQN 170
>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
sapiens]
Length = 874
Score = 107 bits (268), Expect = 7e-23
Identities = 66/241 (27%), Positives = 119/241 (49%), Gaps = 16/241 (6%)
Query: 1264 FIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQF---DQDHNLDLAEKDFTVNTVAGA 1320
F+ +CI+ +E G++ G+YR+ G S+++ L ++D+ + + T+
Sbjct: 397 FVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDNKTITSG 456
Query: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
+K++ L +PL+ Y + D + A K +D+ ++ A+ ++ K P++N E+ +I HL
Sbjct: 457 LKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLV 516
Query: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
KVS +++ NLMT NL + F PTLMR T+ A+ + ++E+ I+ F+ P
Sbjct: 517 KVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAP 576
Query: 1441 ITEPPGARPSSPS----------AVASTVPFLTSTPVTSQP---SPPQSPPPTPQSPMQP 1487
P +P S S + S P TP ++P S SP TP ++
Sbjct: 577 DPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIES 636
Query: 1488 L 1488
L
Sbjct: 637 L 637
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 105 bits (262), Expect = 3e-22
Identities = 52/172 (30%), Positives = 98/172 (56%), Gaps = 2/172 (1%)
Query: 1238 TKATWESNYFGVPLTTVVTPEKP-IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296
T + ++ FGV ++ V E+ +P + +C+E +E G+ GIYR+SG +++++L+
Sbjct: 590 TPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALK 649
Query: 1297 RQFDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLH 1355
FD ++ ++ L D +N +AG +K +F ELP+PL+ + +E ++D K +
Sbjct: 650 AVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKEN 709
Query: 1356 ALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRP 1407
+ +L+ P N F +++ HL +V+ +N M+ NL+ F PTL+RP
Sbjct: 710 CMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRP 761
>gi|38679957 active breakpoint cluster region-related protein isoform
a [Homo sapiens]
Length = 859
Score = 105 bits (262), Expect = 3e-22
Identities = 52/172 (30%), Positives = 98/172 (56%), Gaps = 2/172 (1%)
Query: 1238 TKATWESNYFGVPLTTVVTPEKP-IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296
T + ++ FGV ++ V E+ +P + +C+E +E G+ GIYR+SG +++++L+
Sbjct: 636 TPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALK 695
Query: 1297 RQFDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLH 1355
FD ++ ++ L D +N +AG +K +F ELP+PL+ + +E ++D K +
Sbjct: 696 AVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKEN 755
Query: 1356 ALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRP 1407
+ +L+ P N F +++ HL +V+ +N M+ NL+ F PTL+RP
Sbjct: 756 CMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRP 807
>gi|38679954 active breakpoint cluster region-related protein isoform
b [Homo sapiens]
Length = 822
Score = 105 bits (262), Expect = 3e-22
Identities = 52/172 (30%), Positives = 98/172 (56%), Gaps = 2/172 (1%)
Query: 1238 TKATWESNYFGVPLTTVVTPEKP-IPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296
T + ++ FGV ++ V E+ +P + +C+E +E G+ GIYR+SG +++++L+
Sbjct: 599 TPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALK 658
Query: 1297 RQFDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLH 1355
FD ++ ++ L D +N +AG +K +F ELP+PL+ + +E ++D K +
Sbjct: 659 AVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKEN 718
Query: 1356 ALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRP 1407
+ +L+ P N F +++ HL +V+ +N M+ NL+ F PTL+RP
Sbjct: 719 CMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRP 770
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 104 bits (260), Expect = 6e-22
Identities = 76/263 (28%), Positives = 124/263 (47%), Gaps = 15/263 (5%)
Query: 1233 PRPSITKATW-ESNYFGVPLTTVVTPE-KPIPIFIERCIEYIEATGLSTEGIYRVSGNKS 1290
P+ + W E FG PL +T + I IE C+ + G+ EG++RV+ + S
Sbjct: 238 PQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSAS 297
Query: 1291 EMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDR 1350
+++ L+ D +D+ E + +AGA+KS+ ELP+PL+ + + + ++A + ++
Sbjct: 298 KLKKLKAALDCCV-VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQ 356
Query: 1351 EQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFS 1410
++KL AL +K PK NH +Y+I L+K+S VN MT N++I P L+ P
Sbjct: 357 DKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAE 416
Query: 1411 ---TMDALTATRTYQTIIELFIQQCPFFFYNRPITEPPGARPSSPSAVASTVPFLTSTPV 1467
T T + IIE IQ +FF P + S V +
Sbjct: 417 GNITEMMTTVSLQIVGIIEPIIQHADWFF-------PGEIEFNITGNYGSPVHVNHNANY 469
Query: 1468 TSQPSPPQSPPP--TPQSPMQPL 1488
+S PSP P P+ +PL
Sbjct: 470 SSMPSPDMDPADRRQPEQARRPL 492
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 104 bits (259), Expect = 7e-22
Identities = 51/180 (28%), Positives = 97/180 (53%), Gaps = 4/180 (2%)
Query: 1265 IERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKD----FTVNTVAGA 1320
I +CI +E G++ +G+YR+ G S ++ L E D + + T+ A
Sbjct: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSA 452
Query: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
+K++ LP PL+ Y Q ++A K+ ++E ++ + ++ + P++N ++ + +++HL
Sbjct: 453 LKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLA 512
Query: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
V++N+K NLMT NL + F PTL+RP T+ A+ + +IE+ I+ F P
Sbjct: 513 NVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTVP 572
>gi|7662208 GTPase regulator associated with the focal adhesion kinase
pp125 isoform a [Homo sapiens]
Length = 814
Score = 104 bits (259), Expect = 7e-22
Identities = 51/180 (28%), Positives = 97/180 (53%), Gaps = 4/180 (2%)
Query: 1265 IERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKD----FTVNTVAGA 1320
I +CI +E G++ +G+YR+ G S ++ L E D + + T+ A
Sbjct: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSA 452
Query: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
+K++ LP PL+ Y Q ++A K+ ++E ++ + ++ + P++N ++ + +++HL
Sbjct: 453 LKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLA 512
Query: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
V++N+K NLMT NL + F PTL+RP T+ A+ + +IE+ I+ F P
Sbjct: 513 NVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTVP 572
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sapiens]
Length = 731
Score = 103 bits (258), Expect = 1e-21
Identities = 74/227 (32%), Positives = 111/227 (48%), Gaps = 26/227 (11%)
Query: 1208 ETDEDPRRRNILRSLRRNTKKPKPKPRPSIT-KATWESNYFGVPLTTVVTPE-KPIPIFI 1265
E E R RN L+ L K+P P S+ + FG L ++ E +P F+
Sbjct: 486 EGTEQNRVRNKLKRLI--AKRP---PLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
Query: 1266 ERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFD------------------QDHNLDL 1307
CI ++ GL +GIYRVSGN + ++ L+ D Q+ LDL
Sbjct: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
Query: 1308 AEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPK 1366
++ ++ V GA+K F ELP PLVP + A +++ EQ L ++E++ PK
Sbjct: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPK 660
Query: 1367 ENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMD 1413
NH+ +Y++ HL +V ++ N MT NL I F PTL RP+ T D
Sbjct: 661 PNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSD 707
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sapiens]
Length = 547
Score = 103 bits (258), Expect = 1e-21
Identities = 74/227 (32%), Positives = 111/227 (48%), Gaps = 26/227 (11%)
Query: 1208 ETDEDPRRRNILRSLRRNTKKPKPKPRPSIT-KATWESNYFGVPLTTVVTPE-KPIPIFI 1265
E E R RN L+ L K+P P S+ + FG L ++ E +P F+
Sbjct: 302 EGTEQNRVRNKLKRLI--AKRP---PLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 356
Query: 1266 ERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFD------------------QDHNLDL 1307
CI ++ GL +GIYRVSGN + ++ L+ D Q+ LDL
Sbjct: 357 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 416
Query: 1308 AEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPK 1366
++ ++ V GA+K F ELP PLVP + A +++ EQ L ++E++ PK
Sbjct: 417 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPK 476
Query: 1367 ENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMD 1413
NH+ +Y++ HL +V ++ N MT NL I F PTL RP+ T D
Sbjct: 477 PNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSD 523
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 103 bits (257), Expect = 1e-21
Identities = 66/239 (27%), Positives = 117/239 (48%), Gaps = 13/239 (5%)
Query: 1221 SLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKP-IPIFIERCIEYIEATGLST 1279
S++ N+++ K PS ++ FGV + V E+ +P + +C+E IE G+
Sbjct: 986 SVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEE 1041
Query: 1280 EGIYRVSGNKSEMESLQRQFDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQ 1338
GIYRVSG +++++L+ FD ++ ++ + + VN +AG +K +F ELP+PL
Sbjct: 1042 VGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFY 1101
Query: 1339 IDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSI 1398
+ E ++D K + +L P+ N F +++ HL +V+ VN M+ NL+
Sbjct: 1102 PNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLAT 1161
Query: 1399 CFWPTLMRPD-------FSTMDALTATRTYQTIIELFIQQCPFFFYNRPITEPPGARPS 1450
F PTL+RP + +T T ++ + +Q +F I P R S
Sbjct: 1162 VFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQS 1220
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 103 bits (257), Expect = 1e-21
Identities = 66/239 (27%), Positives = 117/239 (48%), Gaps = 13/239 (5%)
Query: 1221 SLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKP-IPIFIERCIEYIEATGLST 1279
S++ N+++ K PS ++ FGV + V E+ +P + +C+E IE G+
Sbjct: 1030 SVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEE 1085
Query: 1280 EGIYRVSGNKSEMESLQRQFDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQ 1338
GIYRVSG +++++L+ FD ++ ++ + + VN +AG +K +F ELP+PL
Sbjct: 1086 VGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFY 1145
Query: 1339 IDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSI 1398
+ E ++D K + +L P+ N F +++ HL +V+ VN M+ NL+
Sbjct: 1146 PNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLAT 1205
Query: 1399 CFWPTLMRPD-------FSTMDALTATRTYQTIIELFIQQCPFFFYNRPITEPPGARPS 1450
F PTL+RP + +T T ++ + +Q +F I P R S
Sbjct: 1206 VFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQS 1264
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapiens]
Length = 1085
Score = 101 bits (252), Expect = 5e-21
Identities = 63/217 (29%), Positives = 112/217 (51%), Gaps = 10/217 (4%)
Query: 1199 KGDNAVIPYETDEDPRRRNILRSLRRN---TKKPKPKPRP-----SITKATWESNYFGVP 1250
+G N + + D +R + R T+ P P+P S ++ + + F
Sbjct: 448 EGSNLITKLQAKHDLLQRTLGEGHRAEYMTTRPPNVPPKPQKHRKSRPRSQYNTKLFNGD 507
Query: 1251 LTTVVTPE-KPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHN-LDLA 1308
L T V + IP+ +E CI +I GL +GI+RVSG++ E+ ++ F++ N L
Sbjct: 508 LETFVKDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLADD 567
Query: 1309 EKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKEN 1368
+ + +N+VAG +K +F L +PL P DL+ +I++ ++ ++++L P+
Sbjct: 568 QSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERALHIRKLLLTLPRSV 627
Query: 1369 HEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLM 1405
V +Y+ + LN +S + N+M NL+ICF PTLM
Sbjct: 628 LIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLM 664
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 101 bits (251), Expect = 6e-21
Identities = 61/193 (31%), Positives = 109/193 (56%), Gaps = 7/193 (3%)
Query: 1243 ESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD 1302
E +FGV + ++ + + +PI +E+ +E++E GL TEG+YR SG + L++ D
Sbjct: 1694 EPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD 1753
Query: 1303 HNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLK 1362
E +F ++ + G +K + ELP+PL+ + D + A ++ +++++L A+ VL+
Sbjct: 1754 PAAVKLE-NFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLE 1812
Query: 1363 KFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATR-- 1419
P+ NH + +I HL KV+ VN M+ L+I F P L+R PD S D LT+ +
Sbjct: 1813 HLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNS--DPLTSMKDV 1870
Query: 1420 -TYQTIIELFIQQ 1431
T +E+ I++
Sbjct: 1871 LKITTCVEMLIKE 1883
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 101 bits (251), Expect = 6e-21
Identities = 61/193 (31%), Positives = 109/193 (56%), Gaps = 7/193 (3%)
Query: 1243 ESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD 1302
E +FGV + ++ + + +PI +E+ +E++E GL TEG+YR SG + L++ D
Sbjct: 1694 EPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD 1753
Query: 1303 HNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLK 1362
E +F ++ + G +K + ELP+PL+ + D + A ++ +++++L A+ VL+
Sbjct: 1754 PAAVKLE-NFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLE 1812
Query: 1363 KFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATR-- 1419
P+ NH + +I HL KV+ VN M+ L+I F P L+R PD S D LT+ +
Sbjct: 1813 HLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNS--DPLTSMKDV 1870
Query: 1420 -TYQTIIELFIQQ 1431
T +E+ I++
Sbjct: 1871 LKITTCVEMLIKE 1883
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a [Homo
sapiens]
Length = 1099
Score = 100 bits (248), Expect = 1e-20
Identities = 58/185 (31%), Positives = 98/185 (52%), Gaps = 6/185 (3%)
Query: 1228 KPKPKPRPSITKATWESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSG 1287
KP+ RP + G + + IP+ +E CI YI GL +GI+RV G
Sbjct: 486 KPQKMRRPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPG 545
Query: 1288 NKSEMESLQRQFDQDHNL---DLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEA 1344
++ E+ ++ F++ + D E+D +N+VAG +K +F L +PL P DL+
Sbjct: 546 SQVEVNDIKNSFERGEDPLVDDQNERD--INSVAGVLKLYFRGLENPLFPKERFQDLIST 603
Query: 1345 HKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTL 1404
K+ + +++H ++++L P+ V +Y+ + LN +S + N+M NL+ICF PTL
Sbjct: 604 IKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTL 663
Query: 1405 MR-PD 1408
M PD
Sbjct: 664 MHIPD 668
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,110,215
Number of Sequences: 37866
Number of extensions: 2826273
Number of successful extensions: 21945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 248
Number of HSP's that attempted gapping in prelim test: 17419
Number of HSP's gapped (non-prelim): 3906
length of query: 1499
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1384
effective length of database: 13,892,928
effective search space: 19227812352
effective search space used: 19227812352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.