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Search of human proteins with 110227866
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110227866 unc-84 homolog A isoform b [Homo sapiens]
(702 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110227866 unc-84 homolog A isoform b [Homo sapiens] 1408 0.0
gi|195972890 unc-84 homolog A isoform a [Homo sapiens] 1387 0.0
gi|31742498 unc-84 homolog B [Homo sapiens] 346 5e-95
gi|71834870 Sad1 and UNC84 domain containing 1 [Homo sapiens] 186 5e-47
gi|71834868 Sad1 and UNC84 domain containing 1 [Homo sapiens] 186 5e-47
gi|21361792 sperm associated antigen 4-like [Homo sapiens] 150 4e-36
gi|11037055 sperm associated antigen 4 [Homo sapiens] 144 2e-34
gi|110611218 ribosome binding protein 1 [Homo sapiens] 42 0.003
gi|110611220 ribosome binding protein 1 [Homo sapiens] 42 0.003
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 41 0.003
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 41 0.004
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 40 0.006
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.006
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 40 0.007
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 40 0.010
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 39 0.013
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 39 0.016
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 39 0.021
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 39 0.021
gi|154090997 coiled-coil domain containing 13 [Homo sapiens] 39 0.021
gi|170784854 PTPRF interacting protein, binding protein 2 (lipri... 38 0.028
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 38 0.028
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 38 0.037
gi|4504063 golgin 97 [Homo sapiens] 38 0.037
gi|118498356 kinectin 1 isoform a [Homo sapiens] 37 0.048
gi|33620775 kinectin 1 isoform a [Homo sapiens] 37 0.048
gi|238908495 similar to pleckstrin homology domain protein (5V32... 37 0.062
gi|21493045 A-kinase anchor protein 6 [Homo sapiens] 37 0.062
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.082
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.082
>gi|110227866 unc-84 homolog A isoform b [Homo sapiens]
Length = 702
Score = 1408 bits (3645), Expect = 0.0
Identities = 702/702 (100%), Positives = 702/702 (100%)
Query: 1 MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ 60
MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ
Sbjct: 1 MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ 60
Query: 61 VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG 120
VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG
Sbjct: 61 VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG 120
Query: 121 DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKWKAASGVFWWL 180
DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKWKAASGVFWWL
Sbjct: 121 DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKWKAASGVFWWL 180
Query: 181 GIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNW 240
GIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNW
Sbjct: 181 GIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNW 240
Query: 241 ASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENL 300
ASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENL
Sbjct: 241 ASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENL 300
Query: 301 RELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILG 360
RELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILG
Sbjct: 301 RELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILG 360
Query: 361 KLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVD 420
KLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVD
Sbjct: 361 KLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVD 420
Query: 421 AVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVT 480
AVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVT
Sbjct: 421 AVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVT 480
Query: 481 HHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGG 540
HHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGG
Sbjct: 481 HHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGG 540
Query: 541 SILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLS 600
SILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLS
Sbjct: 541 SILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLS 600
Query: 601 MMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQM 660
MMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQM
Sbjct: 601 MMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQM 660
Query: 661 FQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK 702
FQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
Sbjct: 661 FQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK 702
>gi|195972890 unc-84 homolog A isoform a [Homo sapiens]
Length = 785
Score = 1387 bits (3590), Expect = 0.0
Identities = 702/735 (95%), Positives = 702/735 (95%), Gaps = 33/735 (4%)
Query: 1 MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ 60
MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ
Sbjct: 51 MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ 110
Query: 61 VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG 120
VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG
Sbjct: 111 VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG 170
Query: 121 DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK----------- 169
DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK
Sbjct: 171 DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRI 230
Query: 170 -----------W-----------KAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNIC 207
W KAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNIC
Sbjct: 231 GAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNIC 290
Query: 208 KFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPL 267
KFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPL
Sbjct: 291 KFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPL 350
Query: 268 QGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSAS 327
QGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSAS
Sbjct: 351 QGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSAS 410
Query: 328 VRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQ 387
VRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQ
Sbjct: 411 VRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQ 470
Query: 388 LLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSL 447
LLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSL
Sbjct: 471 LLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSL 530
Query: 448 EQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGI 507
EQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGI
Sbjct: 531 EQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGI 590
Query: 508 TEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWY 567
TEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWY
Sbjct: 591 TEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWY 650
Query: 568 FSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAP 627
FSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAP
Sbjct: 651 FSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAP 710
Query: 628 KDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPE 687
KDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPE
Sbjct: 711 KDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPE 770
Query: 688 YTCLYRFRVHGEPVK 702
YTCLYRFRVHGEPVK
Sbjct: 771 YTCLYRFRVHGEPVK 785
>gi|31742498 unc-84 homolog B [Homo sapiens]
Length = 717
Score = 346 bits (887), Expect = 5e-95
Identities = 264/762 (34%), Positives = 384/762 (50%), Gaps = 109/762 (14%)
Query: 1 MSRRSLRLATTACTLGDGEAVGADSGTSSAVS----LKNRAARTTKQRRSTNKSAFSINH 56
MSRRS RL T + GD + + G+S A S K+ RT K R+S+N S
Sbjct: 1 MSRRSQRL--TRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSSNMKRLS--- 54
Query: 57 VSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDG-DLK------ 109
+ Q+ S +H S ++ ESW +++++ G + G DL+
Sbjct: 55 PAPQLGPSSDAHTSYYS--------ESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRG 106
Query: 110 -GGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVL----TAHPAAPGPVSRVYSR 164
GG++++ + +G VG A G S S S D + ++ + SR
Sbjct: 107 TGGSESS-RASGLVGRKATEDFLGSS----SGYSSEDDYVGYSDVDQQSSSSRLRSAVSR 161
Query: 165 DRNQKWKAASG-------VFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLF 217
+ W A+ ++WW G WY+ T S L+VF+LTR ++ FL L+PL
Sbjct: 162 AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLL 221
Query: 218 LLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTTSRLKQP-LQGD 270
LL G F+ +F P L +W + ++R D+ + +R P Q +
Sbjct: 222 LLTC--LTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------ARDSSPHFQAE 273
Query: 271 SEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-EGGAAGPS---- 325
MS V L N ++ L++L+ R +GG G S
Sbjct: 274 QRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDT 328
Query: 326 -------ASVRDAVGQPP--RETDFMAFHQEHEVRMSHL---EDILGKLREKSEAIQKEL 373
S R+A + RET + +R H ED+ K+ S+ + +
Sbjct: 329 LALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARI 388
Query: 374 EQTKQK----TISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGC--------ETVDA 421
+Q K + T + E + + L+ +L L+ EL++ ++ + + A
Sbjct: 389 QQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQA 448
Query: 422 VQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTH 481
V++ V+ Q + + GG LLQR ++Q LR+L+ +IL
Sbjct: 449 VRDDVESQFPAWISQFLARG--GGGRVGLLQR--------EEMQAQLRELESKILT---- 494
Query: 482 HVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESG 538
HV+ + EA S + + G G+TE Q IV AL+ YS+D+ G+ D+ALESG
Sbjct: 495 HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESG 554
Query: 539 GGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVR 598
G S++STRCSETYETKTAL+SLFGIPLWY SQSPRV++QPD++PGNCWAF+G QG+ VVR
Sbjct: 555 GASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVR 614
Query: 599 LSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESL 658
LS I P A TLEH+PK LSP ISSAPKDFA++G + + Q+EG LLG+FTYDQDGE +
Sbjct: 615 LSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPI 674
Query: 659 QMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEP 700
Q F + P +Q+VELRI +NWGHPEYTC+YRFRVHGEP
Sbjct: 675 QTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEP 715
>gi|71834870 Sad1 and UNC84 domain containing 1 [Homo sapiens]
Length = 357
Score = 186 bits (473), Expect = 5e-47
Identities = 89/188 (47%), Positives = 124/188 (65%), Gaps = 1/188 (0%)
Query: 515 IVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRV 574
+VN LK +D+ M D+AL+S G SI+ SE+Y+ A + GI P +
Sbjct: 169 LVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHEMPPDI 228
Query: 575 VIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYG 634
++QPD+YPG CWAF GSQG+ +++L+ I P A T+EHI + +SP+GNISSAPK+F+VYG
Sbjct: 229 ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYG 288
Query: 635 LENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRF 694
+ + + E LGQF Y++ G ++Q F+ L+ V+L IFSNWGHP+YTCLYRF
Sbjct: 289 ITKKCEGEEIFLGQFIYNKTGTTVQTFE-LQHAVSEYLLCVKLNIFSNWGHPKYTCLYRF 347
Query: 695 RVHGEPVK 702
RVHG P K
Sbjct: 348 RVHGTPGK 355
>gi|71834868 Sad1 and UNC84 domain containing 1 [Homo sapiens]
Length = 357
Score = 186 bits (473), Expect = 5e-47
Identities = 89/188 (47%), Positives = 124/188 (65%), Gaps = 1/188 (0%)
Query: 515 IVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRV 574
+VN LK +D+ M D+AL+S G SI+ SE+Y+ A + GI P +
Sbjct: 169 LVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHEMPPDI 228
Query: 575 VIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYG 634
++QPD+YPG CWAF GSQG+ +++L+ I P A T+EHI + +SP+GNISSAPK+F+VYG
Sbjct: 229 ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYG 288
Query: 635 LENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRF 694
+ + + E LGQF Y++ G ++Q F+ L+ V+L IFSNWGHP+YTCLYRF
Sbjct: 289 ITKKCEGEEIFLGQFIYNKTGTTVQTFE-LQHAVSEYLLCVKLNIFSNWGHPKYTCLYRF 347
Query: 695 RVHGEPVK 702
RVHG P K
Sbjct: 348 RVHGTPGK 355
>gi|21361792 sperm associated antigen 4-like [Homo sapiens]
Length = 379
Score = 150 bits (379), Expect = 4e-36
Identities = 89/231 (38%), Positives = 133/231 (57%), Gaps = 12/231 (5%)
Query: 473 LQILR----NVTHHVSVTKQLPTS-EAVVSAVSEAGASGITEAQARAIVNSALKLYSQDK 527
LQ LR V HH + L S +++ + E A + A+ I +K+ D
Sbjct: 138 LQSLRLYQEKVRHHSGEIQDLRGSMNQLIAKLQEMEAMSDEQKMAQKI----MKMIHGDY 193
Query: 528 TGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWA 587
DFAL+S G SI S TY + A I LW ++Q P V+++P++ PGNCWA
Sbjct: 194 IEKPDFALKSIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWA 253
Query: 588 FKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLG 647
F+G +G + ++L+ ++ + TL+HIPKT+S +G++ +APKDF +YG+E +EE LG
Sbjct: 254 FEGDRGQVTIQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGMEGSPKEE-VFLG 312
Query: 648 QFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHG 698
F + Q +QMF +P AF V+++I SNWG+P +TCLYR RVHG
Sbjct: 313 AFQF-QPENIIQMFPLQNQP-ARAFSAVKVKISSNWGNPGFTCLYRVRVHG 361
>gi|11037055 sperm associated antigen 4 [Homo sapiens]
Length = 437
Score = 144 bits (364), Expect = 2e-34
Identities = 71/194 (36%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Query: 505 SGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIP 564
S + A + + + ++D D+AL S G SI + S Y +
Sbjct: 231 STVRAANSERVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFS 290
Query: 565 LWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNIS 624
W +++ P V+++P ++PGNCWAF+G QG +V++L + + TL+H P ++ TG +
Sbjct: 291 FWNYARPPTVILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGAN 350
Query: 625 SAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWG 684
SAP+DFAV+GL+ Y E LG+FT+D + +Q F L+ AF V+++I SNWG
Sbjct: 351 SAPRDFAVFGLQ-VYDETEVSLGKFTFDVEKSEIQTFH-LQNDPPAAFPKVKIQILSNWG 408
Query: 685 HPEYTCLYRFRVHG 698
HP +TCLYR R HG
Sbjct: 409 HPRFTCLYRVRAHG 422
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/249 (22%), Positives = 110/249 (44%), Gaps = 35/249 (14%)
Query: 283 EQQVASLSGQCH-HHGENLRELTTLLQKLQARVDQMEGGAAGPSASV-------RDAVGQ 334
EQ++ ++ + + E+++E+ L K++ +Q+E G A + RDA+ Q
Sbjct: 319 EQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQ 378
Query: 335 PPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QKTISAVGEQLL--- 389
+ + + ++R L + +L EKSEA++++ +Q K + +A +Q+L
Sbjct: 379 ATSQVESKQNAELAKLRQE-LSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQ 437
Query: 390 ----PTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGG 445
+ E LQ LD++ EL H ++ ++ A E+ Q QQ
Sbjct: 438 ASHRESEEALQKRLDEVSRELC---HTQSSHASLRADAEKAQEQ-----------QQQMA 483
Query: 446 SLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGAS 505
L LQ ++ SK + L L Q+ + +T+++ + EA++ A A
Sbjct: 484 ELHSKLQSSEAEVRSKCE---ELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQ 540
Query: 506 GITEAQARA 514
+ +QA A
Sbjct: 541 DVQASQAEA 549
Score = 32.7 bits (73), Expect = 1.2
Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 53/210 (25%)
Query: 216 LFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFP 275
L LL LS+ Q N+ +L L + P + S+L++
Sbjct: 634 LLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLRE---------- 683
Query: 276 WHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQP 335
E+ ++L +C + L E +L+ LQ V++ E R VG
Sbjct: 684 ------AEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEE-------QVWRAKVGAA 730
Query: 336 PRETDFMAFHQEHEVRMSHLEDILGKL----------REKSEAIQKELE----------Q 375
E Q+ V + HLE+I+ KL RE + ++ ELE Q
Sbjct: 731 EEEL------QKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQ 784
Query: 376 TKQKTISAVGEQLLPTVEHLQLELDQLKSE 405
K ++ + + LL + Q +LD KSE
Sbjct: 785 NYAKEVAGLRQLLLES----QSQLDAAKSE 810
Score = 31.6 bits (70), Expect = 2.6
Identities = 45/210 (21%), Positives = 91/210 (43%), Gaps = 32/210 (15%)
Query: 277 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPS---ASVR---- 329
H + +E+ +A+ S +C ++ + + L LL + Q+++D + A S A VR
Sbjct: 767 HLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLS 826
Query: 330 ---------DAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKT 380
D G P + Q+ + LE +EAI ++ EQT+++
Sbjct: 827 EMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLE--------WTEAILED-EQTQRQK 877
Query: 381 ISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSE 440
++A E+ + LQ EL++L+ ++ + E ++ER++ + KL
Sbjct: 878 LTAEFEEAQTSACRLQEELEKLR---TAGPLESSETEEASQLKERLEKE----KKLTSDL 930
Query: 441 DQQGGSLEQLLQRFSSQFVSKGDLQTMLRD 470
+ L++LL+ Q + D L++
Sbjct: 931 GRAATRLQELLKTTQEQLAREKDTVKKLQE 960
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/249 (22%), Positives = 110/249 (44%), Gaps = 35/249 (14%)
Query: 283 EQQVASLSGQCH-HHGENLRELTTLLQKLQARVDQMEGGAAGPSASV-------RDAVGQ 334
EQ++ ++ + + E+++E+ L K++ +Q+E G A + RDA+ Q
Sbjct: 319 EQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQ 378
Query: 335 PPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QKTISAVGEQLL--- 389
+ + + ++R L + +L EKSEA++++ +Q K + +A +Q+L
Sbjct: 379 ATSQVESKQNAELAKLRQE-LSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQ 437
Query: 390 ----PTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGG 445
+ E LQ LD++ EL H ++ ++ A E+ Q QQ
Sbjct: 438 ASHRESEEALQKRLDEVSRELC---HTQSSHASLRADAEKAQEQ-----------QQQMA 483
Query: 446 SLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGAS 505
L LQ ++ SK + L L Q+ + +T+++ + EA++ A A
Sbjct: 484 ELHSKLQSSEAEVRSKCE---ELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQ 540
Query: 506 GITEAQARA 514
+ +QA A
Sbjct: 541 DVQASQAEA 549
Score = 32.7 bits (73), Expect = 1.2
Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 53/210 (25%)
Query: 216 LFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFP 275
L LL LS+ Q N+ +L L + P + S+L++
Sbjct: 634 LLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLRE---------- 683
Query: 276 WHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQP 335
E+ ++L +C + L E +L+ LQ V++ E R VG
Sbjct: 684 ------AEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEE-------QVWRAKVGAA 730
Query: 336 PRETDFMAFHQEHEVRMSHLEDILGKL----------REKSEAIQKELE----------Q 375
E Q+ V + HLE+I+ KL RE + ++ ELE Q
Sbjct: 731 EEEL------QKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQ 784
Query: 376 TKQKTISAVGEQLLPTVEHLQLELDQLKSE 405
K ++ + + LL + Q +LD KSE
Sbjct: 785 NYAKEVAGLRQLLLES----QSQLDAAKSE 810
Score = 31.6 bits (70), Expect = 2.6
Identities = 45/210 (21%), Positives = 91/210 (43%), Gaps = 32/210 (15%)
Query: 277 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPS---ASVR---- 329
H + +E+ +A+ S +C ++ + + L LL + Q+++D + A S A VR
Sbjct: 767 HLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLS 826
Query: 330 ---------DAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKT 380
D G P + Q+ + LE +EAI ++ EQT+++
Sbjct: 827 EMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLE--------WTEAILED-EQTQRQK 877
Query: 381 ISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSE 440
++A E+ + LQ EL++L+ ++ + E ++ER++ + KL
Sbjct: 878 LTAEFEEAQTSACRLQEELEKLR---TAGPLESSETEEASQLKERLEKE----KKLTSDL 930
Query: 441 DQQGGSLEQLLQRFSSQFVSKGDLQTMLRD 470
+ L++LL+ Q + D L++
Sbjct: 931 GRAATRLQELLKTTQEQLAREKDTVKKLQE 960
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/144 (27%), Positives = 71/144 (49%), Gaps = 7/144 (4%)
Query: 262 RLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGA 321
+L+Q LQ +E P + + Q+VA+L+ HG L L +L+ + +++
Sbjct: 360 KLQQTLQ-KAETLP-EIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQ--R 415
Query: 322 AGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QK 379
A + D + ET + +E HL++ +G L EK+ ++ +E+ K Q
Sbjct: 416 ARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKN-SLSEEIANMKKLQD 474
Query: 380 TISAVGEQLLPTVEHLQLELDQLK 403
+ EQLL +E +Q+E+DQL+
Sbjct: 475 ELLLNKEQLLAEMERMQMEIDQLR 498
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 40.8 bits (94), Expect = 0.004
Identities = 58/223 (26%), Positives = 93/223 (41%), Gaps = 23/223 (10%)
Query: 262 RLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQ----- 316
RLK+ Q SE + EQQVA L + E L+E T +LQ ++D+
Sbjct: 436 RLKEQRQLSSEK-----LMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQH 490
Query: 317 MEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQT 376
E A S + + Q E + + ++ +LE +L K +E ++KE E
Sbjct: 491 QEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQ-KIQNLEALLQKSKENISLLEKEREDL 549
Query: 377 KQKTISAVGE-----QLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVR 431
K + GE QL LQ ++ QL +L K E+ QE + QV+
Sbjct: 550 YAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKL------KNQSESHKQAQENLHDQVQ 603
Query: 432 EMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQ 474
E L + + SLE + +SQ + + L D+Q++
Sbjct: 604 EQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQL-DIQIK 645
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 40.4 bits (93), Expect = 0.006
Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 18/199 (9%)
Query: 294 HHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMS 353
H E L L+ KL+ +VD++EG + + + + + ++E M
Sbjct: 1023 HMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRE---SME 1079
Query: 354 HLEDILGKLREKSEAIQKELEQTKQKTISAVG--EQLLPTVEHLQLELDQLKSELSSWR- 410
+LE L E+ + EL Q K + G QL TV+ LQ ++ LK +L + R
Sbjct: 1080 NLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERT 1139
Query: 411 -HVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLR 469
K E D Q+ D+ R E+ G SL QL + + +K Q + R
Sbjct: 1140 TRAKMERERADLTQDLADLNER-------LEEVGGSSLAQL--EITKKQETK--FQKLHR 1188
Query: 470 DLQLQILRNVTHHVSVTKQ 488
D++ L T S+ K+
Sbjct: 1189 DMEEATLHFETTSASLKKR 1207
Score = 37.7 bits (86), Expect = 0.037
Identities = 35/161 (21%), Positives = 76/161 (47%), Gaps = 15/161 (9%)
Query: 346 QEHEVRMSHLEDILGKLREKSEAIQKELEQTK------QKTISAVGEQLLPTVEHLQLEL 399
+E ++ +E + + E+ +Q LE+T+ + I +LL L+ +L
Sbjct: 1529 REGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKL 1588
Query: 400 DQLKSELSSWRHVKTGCETVDAVQERVDVQVR---EMVKLLFSEDQQGGSLEQLL----Q 452
+ E+ ++R K C T+D++Q +D + + E+ +L ++ +E L +
Sbjct: 1589 SEKDEEIENFRR-KQQC-TIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANR 1646
Query: 453 RFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSE 493
+ S S G LQ ++DLQ+Q+ + + + +Q+ +E
Sbjct: 1647 QVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAE 1687
Score = 34.3 bits (77), Expect = 0.40
Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 7/123 (5%)
Query: 302 ELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGK 361
+LT L L R++++ G + + +ET F H++ E H E
Sbjct: 1150 DLTQDLADLNERLEEVGGSSLAQLEITKK------QETKFQKLHRDMEEATLHFETTSAS 1203
Query: 362 LREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDA 421
L+++ ELE + + + V ++L LQLE+D L + + K E +
Sbjct: 1204 LKKRHADSLAELE-GQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCT 1262
Query: 422 VQE 424
+ E
Sbjct: 1263 LYE 1265
Score = 33.5 bits (75), Expect = 0.69
Identities = 39/171 (22%), Positives = 86/171 (50%), Gaps = 8/171 (4%)
Query: 350 VRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSW 409
V+ S + + + L+E+ +QK LE+++ + +Q+ T E L L QL++E +
Sbjct: 852 VKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLIL-QLQAEQETL 910
Query: 410 RHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ-FVSK---GDLQ 465
+V+ CE + + +++ +V+E+ + + E++ L ++ + F K DL+
Sbjct: 911 ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLE 970
Query: 466 TMLRDLQLQILRNVTHHV-SVTKQLPTSEAVVSAVSEAGASGITEAQARAI 515
TML + + R H V ++T+++ +S ++ A A + EA + +
Sbjct: 971 TMLVKSEKE-KRTTEHKVKNLTEEVEFLNEDISKLNRA-AKVVQEAHQQTL 1019
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 40.4 bits (93), Expect = 0.006
Identities = 63/265 (23%), Positives = 111/265 (41%), Gaps = 60/265 (22%)
Query: 246 TQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELT- 304
T+ + D ++ + L+ D E +SG+++ + ++ GQ R+L
Sbjct: 589 TEEIKDLEEQLTEGQIAANEALKKDLEGV----ISGLQEYLGTIKGQATQAQNECRKLRD 644
Query: 305 ---TLLQKL---QARVDQMEGGAAGPS------ASVRDAVGQPPR--------ETDFMAF 344
TLLQ+L + DQ+E A A + A+ + + D A+
Sbjct: 645 EKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAY 704
Query: 345 HQEHEVRMSHLEDILGKLREKSE-----------AIQKELEQTKQKTISAVGE------- 386
E E R++ + +L+E+ E A+Q ELE+ +Q +A+G+
Sbjct: 705 EAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEK 764
Query: 387 -----QLLPTVEHLQLELDQLKSELSSWR----HVKTGCETVDAVQERVDVQVREMVKLL 437
+L ++HLQ + + LK +L ++ HV G + V RVD ++R +KL
Sbjct: 765 EQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVD-ELRRKLKLG 823
Query: 438 FSE-------DQQGGSLEQLLQRFS 455
E D G SL L ++FS
Sbjct: 824 TGEMNIHSPSDVLGKSLADLQKQFS 848
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 40.0 bits (92), Expect = 0.007
Identities = 57/250 (22%), Positives = 109/250 (43%), Gaps = 32/250 (12%)
Query: 285 QVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAF 344
++ + H E+ + + +Q+L+A +E + A+ GQ E A
Sbjct: 433 RIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEEL-IKAK 491
Query: 345 HQ---EHEVRMSHLED---ILGKLREKSEAI---QKELEQTKQKTISAVGEQLLPTVEHL 395
Q E + R++HLED +L + R++++ QK++ Q +S +G Q VE L
Sbjct: 492 SQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQ----VEGL 547
Query: 396 QLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFS 455
+ L++L+ ELS + A RV V+++E L +E +L +
Sbjct: 548 RRRLEELQQELSLKDQERV------AEVSRVRVELQEQNGRLQAELAAQEALREKAAALE 601
Query: 456 SQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAI 515
Q L+ M D + +L + + S+ ++L EA ++ + + EAQ +
Sbjct: 602 RQ------LKVMASDHREALLDRESENASLREKLRLREAEIARIRD------EEAQRASF 649
Query: 516 VNSALKLYSQ 525
+ +A+ Y Q
Sbjct: 650 LQNAVLAYVQ 659
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 39.7 bits (91), Expect = 0.010
Identities = 38/185 (20%), Positives = 81/185 (43%), Gaps = 11/185 (5%)
Query: 283 EQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFM 342
E QV GQ +RE +++ + +V + EG VR+ GQ + M
Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201
Query: 343 AFHQ----EHEVRMSHLEDILG----KLREKSEAI--QKELEQTKQKTISAVGEQLLPTV 392
+ E E +M E+ +G ++R++ E + Q+E Q +++ + EQ+
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 393 EHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQ 452
E ++ + +Q++ + K E + E+ + Q+RE + + +++Q E+ ++
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ-EEQMREQEEQMREQEEQMREQEEQMR 320
Query: 453 RFSSQ 457
Q
Sbjct: 321 EQEEQ 325
Score = 34.7 bits (78), Expect = 0.31
Identities = 44/231 (19%), Positives = 93/231 (40%), Gaps = 17/231 (7%)
Query: 247 QRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTL 306
Q V+ + + LK+ L+ D P E QV GQ +RE
Sbjct: 21 QLVETEKSEIQLHIKELKRKLETDKIPLPQ------EGQVREQEGQVREQEGQVREQEGQ 74
Query: 307 LQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKS 366
+++ + +V + EG VR+ GQ RE + QE +VR G++RE+
Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQE-----GQVREQE 128
Query: 367 EAIQKELEQTKQK--TISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQE 424
++++ Q +++ + Q+ ++ + Q++ + R + +
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
Query: 425 RVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQI 475
+ Q+ E + +++Q G E+ +Q+ Q G+ + +R + Q+
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM---GEQEEQMRKQEEQM 236
Score = 32.3 bits (72), Expect = 1.5
Identities = 35/204 (17%), Positives = 91/204 (44%), Gaps = 8/204 (3%)
Query: 279 MSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRE 338
M E+Q+ Q E + E +QK + +V + E +R+ Q +
Sbjct: 215 MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ 274
Query: 339 TDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QKTISAVGEQLLPTVEHLQ 396
+ M +E + + ++RE+ E ++++ EQ + ++ + EQ+ E +
Sbjct: 275 EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW 334
Query: 397 LELDQL-KSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFS 455
+ +Q+ + + W+ + E + +Q++ + QVR+ + + +++Q E+ +++
Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ-EEQVRKQEEQMRKQEEQMRKQEEQMRKQE 393
Query: 456 SQFVSK----GDLQTMLRDLQLQI 475
Q + G+ + +R+ + Q+
Sbjct: 394 EQMGEQKEQMGEQKEQMREQEEQM 417
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 39.3 bits (90), Expect = 0.013
Identities = 39/201 (19%), Positives = 82/201 (40%), Gaps = 6/201 (2%)
Query: 299 NLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDI 358
+L ++ +++LQ D+ G SA R + Q + + +E E MS ++++
Sbjct: 378 HLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTL--REEKECSMSRVQEL 435
Query: 359 LGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCET 418
L E + + S V +QL EHL+ EL+ L +L + G
Sbjct: 436 ETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSR 495
Query: 419 VDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQR----FSSQFVSKGDLQTMLRDLQLQ 474
++ QE +++ +L + + + + +Q S +L+ L +LQ
Sbjct: 496 LNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSG 555
Query: 475 ILRNVTHHVSVTKQLPTSEAV 495
++ ++ +T L + + V
Sbjct: 556 FVKLTNENMEITSALQSEQHV 576
Score = 39.3 bits (90), Expect = 0.013
Identities = 61/230 (26%), Positives = 93/230 (40%), Gaps = 42/230 (18%)
Query: 308 QKLQARVD----QMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLR 363
Q+LQA + ++EG A A V+D G ++E E R+ LE
Sbjct: 463 QQLQAEAEHLRKELEGLAGQLQAQVQDNEG-------LSRLNREQEERLLELERAAELWG 515
Query: 364 EKSEAIQKELE--QTKQKTISAV---GEQLLPTVEHLQLELDQLKSE-------LSSWRH 411
E++EA ++ LE Q + TIS +L + LQ +L +E L S +H
Sbjct: 516 EQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQH 575
Query: 412 VKTGC--------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGD 463
VK E + ++E V+++ +E L DQ G L+Q + + K
Sbjct: 576 VKRELGKKLGELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEV 635
Query: 464 LQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQAR 513
L L LQ Q++ QL EA AV+E + E Q R
Sbjct: 636 LHNQLL-LQTQLV----------DQLQQQEAQGKAVAEMARQELQETQER 674
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 38.9 bits (89), Expect = 0.016
Identities = 44/232 (18%), Positives = 109/232 (46%), Gaps = 21/232 (9%)
Query: 298 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 357
+ L+E + LQA++ Q + A VR+ + R + H++ +++ D
Sbjct: 190 QQLQEKEEFISTLQAQLSQTQAEQAAQQV-VRE---KDARFETQVRLHEDELLQLVTQAD 245
Query: 358 ILGKLREKSEAIQKELEQTKQKTISAVG-----EQLLPTVEH----LQLELDQLKSELSS 408
+ ++++K +Q++LE+ ++ + +Q L E L +L Q+++E ++
Sbjct: 246 VETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNT 305
Query: 409 WRH-VKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTM 467
R+ V+T E + E+++++V E KL F Q+ + LL++F ++ +L++
Sbjct: 306 LRNTVETEREESKILLEKMELEVAER-KLSFHNLQE--EMHHLLEQFEQAGQAQAELESR 362
Query: 468 LRDLQ----LQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAI 515
L+ ++ +H +S+ K ++ A+ + + + + +A+
Sbjct: 363 YSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAV 414
Score = 37.7 bits (86), Expect = 0.037
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 16/202 (7%)
Query: 277 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDA-VGQP 335
H + ++A L + + L +L+ L+K + + +EG A ++++
Sbjct: 2298 HLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYE 2357
Query: 336 PRETDFMAFHQ-----EHEVRMSHLEDILGKLREKSEAIQ---KELEQTKQKTISAVGEQ 387
ETD A + E+ M + I+ L K EAIQ EL Q K I + E
Sbjct: 2358 QLETDLQASRELTSRLHEEINMKE-QKIISLLSGKEEAIQVAIAELRQQHDKEIKEL-EN 2415
Query: 388 LLPTVEHLQLEL-DQLKSELSSWRHVKTGCETV--DAVQER--VDVQVREMVKLLFSEDQ 442
LL E + L ++ K + + +T+ + +Q++ +D V+ M L D+
Sbjct: 2416 LLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2475
Query: 443 QGGSLEQLLQRFSSQFVSKGDL 464
G +QL +R S + K L
Sbjct: 2476 IVGDYQQLEERHLSIILEKDQL 2497
Score = 31.6 bits (70), Expect = 2.6
Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 24/216 (11%)
Query: 288 SLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQE 347
SLS C L LT +KL ++ ++ S ++ + +E + + E
Sbjct: 1564 SLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYE 1623
Query: 348 H----EVRMSHL--------EDILGKLREKSEAIQKELEQTKQKTISAVGE------QLL 389
+ R+ H+ +++ GKLR +EA +KE E+ Q+ + E +
Sbjct: 1624 NVSNEAERIQHVVEAVRQEKQELYGKLRS-TEANKKETEKQLQEAEQEMEEMKEKMRKFA 1682
Query: 390 PTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQ 449
+ + LEL++ L + H D +E ++ + + ++ E
Sbjct: 1683 KSKQQKILELEEENDRLRAEVH-----PAGDTAKECMETLLSSNASMKEELERVKMEYET 1737
Query: 450 LLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSV 485
L ++F S K L ++DL+ QI NV+ ++
Sbjct: 1738 LSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANL 1773
Score = 29.6 bits (65), Expect = 10.0
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 17/158 (10%)
Query: 305 TLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLRE 364
+++ +L+A+V Q+E A +A Q + + H H I K ++
Sbjct: 757 SMVTELRAQVKQLEMNLA-------EAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKD 809
Query: 365 -KSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSW----RHVKTGCETV 419
K E +Q EL+ + + + + LQ +L +SE+ RH+ + E +
Sbjct: 810 VKIEVLQNELDDVQLQF-----SEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEEL 864
Query: 420 DAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ 457
+ ++++ +M +LL + + +L+Q ++ Q
Sbjct: 865 SQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQ 902
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 38.5 bits (88), Expect = 0.021
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 21/185 (11%)
Query: 237 VLNWASMHRTQRVDDPQ--DVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCH 294
+ N SMHR + Q + + +L+Q L+ +E P + + Q+VA+LS
Sbjct: 350 IANKDSMHRQTEDKNRQLQERLELAEQKLQQTLR-KAETLP-EVEAELAQRVAALSKAEE 407
Query: 295 HHG---ENLRELTTLL----QKLQARVDQMEGGAAGPSASVRDAVGQPPRET-DFMAFHQ 346
HG E LR++ L Q+LQ R Q E + + D V + E+ + + H
Sbjct: 408 RHGNIEERLRQMEAQLEEKNQELQ-RARQREKMNEEHNKRLSDTVDKLLSESNERLQLHL 466
Query: 347 EHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSEL 406
+ RM+ LED LRE E+ +K+LE+T+ +QL+ +E L+ ELD ++
Sbjct: 467 KE--RMAALEDKNSLLREV-ESAKKQLEETQHDK-----DQLVLNIEALRAELDHMRLRG 518
Query: 407 SSWRH 411
+S H
Sbjct: 519 ASLHH 523
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 38.5 bits (88), Expect = 0.021
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 21/185 (11%)
Query: 237 VLNWASMHRTQRVDDPQ--DVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCH 294
+ N SMHR + Q + + +L+Q L+ +E P + + Q+VA+LS
Sbjct: 350 IANKDSMHRQTEDKNRQLQERLELAEQKLQQTLR-KAETLP-EVEAELAQRVAALSKAEE 407
Query: 295 HHG---ENLRELTTLL----QKLQARVDQMEGGAAGPSASVRDAVGQPPRET-DFMAFHQ 346
HG E LR++ L Q+LQ R Q E + + D V + E+ + + H
Sbjct: 408 RHGNIEERLRQMEAQLEEKNQELQ-RARQREKMNEEHNKRLSDTVDKLLSESNERLQLHL 466
Query: 347 EHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSEL 406
+ RM+ LED LRE E+ +K+LE+T+ +QL+ +E L+ ELD ++
Sbjct: 467 KE--RMAALEDKNSLLREV-ESAKKQLEETQHDK-----DQLVLNIEALRAELDHMRLRG 518
Query: 407 SSWRH 411
+S H
Sbjct: 519 ASLHH 523
>gi|154090997 coiled-coil domain containing 13 [Homo sapiens]
Length = 715
Score = 38.5 bits (88), Expect = 0.021
Identities = 44/191 (23%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 284 QQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMA 343
QQ+ S G + + L + +Q+L+ ++ Q +AG +AS +V PR+ ++
Sbjct: 253 QQLLSSPGTWRGRAQQILVLQSKVQELEKQLGQARSQSAG-TASDELSVYPDPRK---LS 308
Query: 344 FHQEHEVRMSHLE----DILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLEL 399
+++ +R+ LE + L KL + + +Q+ELE+ K+K E + + L E+
Sbjct: 309 AQEKNLLRIRSLEREKQEGLEKLASERDVLQRELEELKKKF-----EGMRSRNKLLSSEM 363
Query: 400 DQLKSELSSW-RHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQF 458
LKS++ + + E +DA+ +++ + L E++ S L Q+ +S+
Sbjct: 364 KTLKSQMGTLVEKGRHDDELIDALMDQLKQLQEILGSLSLQEEKTRVSQHHLDQQLNSEA 423
Query: 459 VSKGDLQTMLR 469
L L+
Sbjct: 424 QRSNSLVAQLQ 434
>gi|170784854 PTPRF interacting protein, binding protein 2 (liprin
beta 2) [Homo sapiens]
Length = 876
Score = 38.1 bits (87), Expect = 0.028
Identities = 40/173 (23%), Positives = 82/173 (47%), Gaps = 32/173 (18%)
Query: 267 LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSA 326
L+GD E+ + QV+ L+ Q GE +R+L L+ Q +++ E
Sbjct: 114 LEGDKES--------LILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAE------EM 159
Query: 327 SVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLRE-KSEAIQKELEQTKQKTISAVG 385
++ + + ET + D++ ++ E K + + E EQ +Q+
Sbjct: 160 LQQELLSRTSLETQKL--------------DLMTEVSELKLKLVGMEKEQREQEEKQRKA 205
Query: 386 EQLLPTVEHLQLELDQLKSELS--SWRHVKTGCETVDAVQERVDVQVREMVKL 436
E+LL + HL++++++L++E + W+ T E V +QE+V ++ E+ +L
Sbjct: 206 EELLQELRHLKIKVEELENERNQYEWKLKATKAE-VAQLQEQVALKDAEIERL 257
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 38.1 bits (87), Expect = 0.028
Identities = 65/286 (22%), Positives = 118/286 (41%), Gaps = 32/286 (11%)
Query: 282 VEQQVASLSGQCHH-------HGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQ 334
V +++A+ + Q H H + EL L + D + G A + + Q
Sbjct: 641 VTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLTKVQAKLSEL--Q 698
Query: 335 PPRETDFMAFHQEH------EVRMSHLEDILGKLREKSEAIQKELEQTKQKTI---SAVG 385
E F E E++++ LE+ L LR + E+++K L + K+K+ S
Sbjct: 699 ETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAE 758
Query: 386 EQLLPTVEHLQLELDQLKSELSSWR--HVKTGCETVDAVQERVDVQVREMVK--LLFSED 441
E++ + Q ELD+L+ L R + E + VQ + Q + L ++D
Sbjct: 759 EEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKD 818
Query: 442 QQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSE 501
+ +++ + + LQ LQ QI + K+L +++ +S V E
Sbjct: 819 EHLQQYQEVCAQRDAYQQKLVQLQEKCLALQAQITALTKQNEQHIKELEKNKSQMSGV-E 877
Query: 502 AGASGITEAQARAIVNSALKLYSQDKTGMVDFALES--GGGSILST 545
A AS +E + + I+N + + +F LE G +IL T
Sbjct: 878 AAASDPSE-KVKKIMNQVFQSLRR------EFELEESYNGRTILGT 916
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 37.7 bits (86), Expect = 0.037
Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 10/197 (5%)
Query: 298 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 357
+ + LT KL+ +VD +EG D + + QE + + + +
Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQ 1078
Query: 358 ILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCE 417
L + +K E L Q+K + A+G QL ++ LQ +++L+ E+ + R + E
Sbjct: 1079 QLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAE 1137
Query: 418 TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILR 477
++R D+ RE+ ++ ++ GG+ ++ + + + Q M RDL+ L+
Sbjct: 1138 -----KQRSDLS-RELEEISERLEEAGGATSAQIEMNKKR---EAEFQKMRRDLEEATLQ 1188
Query: 478 NVTHHVSVTKQLPTSEA 494
+ ++ K+ S A
Sbjct: 1189 HEATAATLRKKHADSVA 1205
Score = 33.9 bits (76), Expect = 0.53
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 28/141 (19%)
Query: 360 GKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEH-------LQLELDQLKSELSSWRHV 412
GK + E I+K++EQ K + +A+ E+ ++EH +QLEL+Q+KSE+ R +
Sbjct: 1524 GKRIHELEKIKKQVEQEKSELQAAL-EEAEASLEHEEGKILRIQLELNQVKSEVD--RKI 1580
Query: 413 KTGCETVD-----------AVQERVDVQVREMVKLLFSEDQQGGSLEQL------LQRFS 455
E +D ++Q +D ++R + + + G L ++ R +
Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
Query: 456 SQFV-SKGDLQTMLRDLQLQI 475
++ + + + Q +L+D QL +
Sbjct: 1641 AEALRNYRNTQAILKDTQLHL 1661
Score = 30.0 bits (66), Expect = 7.6
Identities = 18/78 (23%), Positives = 44/78 (56%), Gaps = 4/78 (5%)
Query: 307 LQKLQARVDQMEGGAAGPSASVRDAV---GQPPRETDFMAFHQEHEVR-MSHLEDILGKL 362
+QKL+ARV ++EG +AV + R+ + + E + + + L+D++ KL
Sbjct: 1816 IQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKL 1875
Query: 363 REKSEAIQKELEQTKQKT 380
+ K ++ +++ E+ ++++
Sbjct: 1876 QAKVKSYKRQAEEAEEQS 1893
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 37.7 bits (86), Expect = 0.037
Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 16/147 (10%)
Query: 344 FHQEHEVRMSHL----EDILGKLREKSEAIQKELEQTKQKTISA--VGEQLLPTVEHLQL 397
F Q+ ++ H+ E+ LGK+ ++ EA +EL +T+++ +++ + L +E LQ
Sbjct: 176 FQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQR 235
Query: 398 ELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ 457
L+ + KTG E+ E+ + +++ +++ L + LQ+ +++
Sbjct: 236 HYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSID----------LQKVTAE 285
Query: 458 FVSKGDLQTMLRDLQLQILRNVTHHVS 484
K D+ T L++ + + + ++S
Sbjct: 286 TQEKEDVITHLQEKVASLEKRLEQNLS 312
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.4 bits (85), Expect = 0.048
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 5/131 (3%)
Query: 277 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPP 336
H + ++ L +C + L E +LQKLQ V+Q E + Q
Sbjct: 1120 HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQ-- 1177
Query: 337 RETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGE--QLLPTVEH 394
++ F + QE E S +DI LR + E ++ ELE+ + + + V E +L +
Sbjct: 1178 MQSSFTSSEQELERLRSENKDI-ENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTE 1236
Query: 395 LQLELDQLKSE 405
LQ +LD SE
Sbjct: 1237 LQKKLDDSYSE 1247
Score = 31.2 bits (69), Expect = 3.4
Identities = 56/267 (20%), Positives = 104/267 (38%), Gaps = 48/267 (17%)
Query: 245 RTQRVDDPQD---VFKPTTSRLKQPLQGDSEAFPWH------------WMSGVEQQVASL 289
+TQ + D QD +FK +LKQ + +FP H +SG+ ++ SL
Sbjct: 959 KTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSL 1018
Query: 290 SGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHE 349
H + +L + + ME A ++D V + +E Q+ E
Sbjct: 1019 KDAVEHQRKKNNDLR------EKNWEAME-ALASTEKMLQDKVNKTSKER-----QQQVE 1066
Query: 350 VRMSHLEDILGKLREK---------SEAIQKELEQTKQKTISAVGEQLLPTVEH------ 394
+++L KL K E + ++ K+ G + + +EH
Sbjct: 1067 AVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEAD 1126
Query: 395 -----LQLELDQLKSELSSWRHVKTGCE-TVDAVQERVDVQVREMVKLLFSEDQQGGSLE 448
LQLE ++ KS L+ + + +V+ + + V+V E K + S E
Sbjct: 1127 EMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSE 1186
Query: 449 QLLQRFSSQFVSKGDLQTMLRDLQLQI 475
Q L+R S+ +L+ L++++
Sbjct: 1187 QELERLRSENKDIENLRREREHLEMEL 1213
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.4 bits (85), Expect = 0.048
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 5/131 (3%)
Query: 277 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPP 336
H + ++ L +C + L E +LQKLQ V+Q E + Q
Sbjct: 1120 HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQ-- 1177
Query: 337 RETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGE--QLLPTVEH 394
++ F + QE E S +DI LR + E ++ ELE+ + + + V E +L +
Sbjct: 1178 MQSSFTSSEQELERLRSENKDI-ENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTE 1236
Query: 395 LQLELDQLKSE 405
LQ +LD SE
Sbjct: 1237 LQKKLDDSYSE 1247
Score = 31.2 bits (69), Expect = 3.4
Identities = 56/267 (20%), Positives = 104/267 (38%), Gaps = 48/267 (17%)
Query: 245 RTQRVDDPQD---VFKPTTSRLKQPLQGDSEAFPWH------------WMSGVEQQVASL 289
+TQ + D QD +FK +LKQ + +FP H +SG+ ++ SL
Sbjct: 959 KTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSL 1018
Query: 290 SGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHE 349
H + +L + + ME A ++D V + +E Q+ E
Sbjct: 1019 KDAVEHQRKKNNDLR------EKNWEAME-ALASTEKMLQDKVNKTSKER-----QQQVE 1066
Query: 350 VRMSHLEDILGKLREK---------SEAIQKELEQTKQKTISAVGEQLLPTVEH------ 394
+++L KL K E + ++ K+ G + + +EH
Sbjct: 1067 AVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEAD 1126
Query: 395 -----LQLELDQLKSELSSWRHVKTGCE-TVDAVQERVDVQVREMVKLLFSEDQQGGSLE 448
LQLE ++ KS L+ + + +V+ + + V+V E K + S E
Sbjct: 1127 EMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSE 1186
Query: 449 QLLQRFSSQFVSKGDLQTMLRDLQLQI 475
Q L+R S+ +L+ L++++
Sbjct: 1187 QELERLRSENKDIENLRREREHLEMEL 1213
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 37.0 bits (84), Expect = 0.062
Identities = 39/183 (21%), Positives = 84/183 (45%), Gaps = 16/183 (8%)
Query: 356 EDILGKLREKSEAIQKELEQTKQ-----KTISAVGEQLLPTVEHLQLELDQLKSELSSWR 410
++ L KL E++E + + EQ ++ + + A +Q V+ L++E +Q+K EL
Sbjct: 164 QEYLDKLMEETEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIKRELELTA 223
Query: 411 HVKTGCE--------TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKG 462
G E +++Q+ ++ E K L ++ L+ L + S Q G
Sbjct: 224 RCLKGVEQEKKELRHLTESLQQTLEELSIEKKKTLEMLEENENHLQTLANQ-SEQPPPSG 282
Query: 463 DLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKL 522
L + LR ++ ++ + + + K++ +E A+ E +Q++A+ NS +L
Sbjct: 283 GLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEE--EREFYSSQSQALQNSLQEL 340
Query: 523 YSQ 525
++
Sbjct: 341 TAE 343
>gi|21493045 A-kinase anchor protein 6 [Homo sapiens]
Length = 2319
Score = 37.0 bits (84), Expect = 0.062
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 43/198 (21%)
Query: 345 HQE-HEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLK 403
HQ+ +E +E + KL E + + + +E T+ T + E+D LK
Sbjct: 770 HQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPP-------------KAEMDDLK 816
Query: 404 SELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGD 463
L + K ++ A++E V+ + ++++L+ S L+ +L+ +SQ+
Sbjct: 817 LYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHK---AGLKDMLRMIASQW----- 868
Query: 464 LQTMLRDLQLQILRNVTHHVSVTKQLPTSEAV-----VSAVSEAGASG--------ITEA 510
++LQ QI R H + + L T +A VS E G EA
Sbjct: 869 -----KELQRQIKRQ---HSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEA 920
Query: 511 QARAIVNSALKLYSQDKT 528
Q A+ +LKLYS+ T
Sbjct: 921 QRDAVEQMSLKLYSEQYT 938
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 36.6 bits (83), Expect = 0.082
Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 10/197 (5%)
Query: 298 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 357
+ + LT KL+ +VD +EG D + + QE + + + +
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 358 ILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCE 417
L + +K E L Q+K + A+G QL ++ LQ +++L+ E+ + R + E
Sbjct: 1081 QLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139
Query: 418 TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILR 477
++R D+ RE+ ++ ++ GG+ ++ + + + Q M RDL+ L+
Sbjct: 1140 -----KQRSDLS-RELEEISERLEEAGGATSAQIEMNKKR---EAEFQKMRRDLEEATLQ 1190
Query: 478 NVTHHVSVTKQLPTSEA 494
+ ++ K+ S A
Sbjct: 1191 HEATAATLRKKHADSVA 1207
Score = 31.6 bits (70), Expect = 2.6
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 21/109 (19%)
Query: 360 GKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEH-------LQLELDQLKSELSSWRHV 412
GK + E I+K++EQ K + +A+ E+ ++EH +QLEL+Q+KSE+ R +
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAAL-EEAEASLEHEEGKILRIQLELNQVKSEVD--RKI 1582
Query: 413 KTGCETVD-----------AVQERVDVQVREMVKLLFSEDQQGGSLEQL 450
E +D ++Q +D ++R + + + G L ++
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631
Score = 31.2 bits (69), Expect = 3.4
Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
Query: 307 LQKLQARVDQMEGGAAGPSASVRDAV---GQPPRETDFMAFHQEHEVR-MSHLEDILGKL 362
+QKL+ARV ++EG +AV + R + + E + + + L+D++ KL
Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1877
Query: 363 REKSEAIQKELEQTKQK--TISAVGEQLLPTVEHLQLELDQLKSELSSWR 410
+ K ++ +++ E+ +++ T A +L +E + D +S+++ R
Sbjct: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 36.6 bits (83), Expect = 0.082
Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 10/197 (5%)
Query: 298 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 357
+ + LT KL+ +VD +EG D + + QE + + + +
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 358 ILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCE 417
L + +K E L Q+K + A+G QL ++ LQ +++L+ E+ + R + E
Sbjct: 1081 QLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139
Query: 418 TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILR 477
++R D+ RE+ ++ ++ GG+ ++ + + + Q M RDL+ L+
Sbjct: 1140 -----KQRSDLS-RELEEISERLEEAGGATSAQIEMNKKR---EAEFQKMRRDLEEATLQ 1190
Query: 478 NVTHHVSVTKQLPTSEA 494
+ ++ K+ S A
Sbjct: 1191 HEATAATLRKKHADSVA 1207
Score = 31.6 bits (70), Expect = 2.6
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 21/109 (19%)
Query: 360 GKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEH-------LQLELDQLKSELSSWRHV 412
GK + E I+K++EQ K + +A+ E+ ++EH +QLEL+Q+KSE+ R +
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAAL-EEAEASLEHEEGKILRIQLELNQVKSEVD--RKI 1582
Query: 413 KTGCETVD-----------AVQERVDVQVREMVKLLFSEDQQGGSLEQL 450
E +D ++Q +D ++R + + + G L ++
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631
Score = 31.2 bits (69), Expect = 3.4
Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
Query: 307 LQKLQARVDQMEGGAAGPSASVRDAV---GQPPRETDFMAFHQEHEVR-MSHLEDILGKL 362
+QKL+ARV ++EG +AV + R + + E + + + L+D++ KL
Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1877
Query: 363 REKSEAIQKELEQTKQK--TISAVGEQLLPTVEHLQLELDQLKSELSSWR 410
+ K ++ +++ E+ +++ T A +L +E + D +S+++ R
Sbjct: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,160,027
Number of Sequences: 37866
Number of extensions: 1145242
Number of successful extensions: 4840
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 4530
Number of HSP's gapped (non-prelim): 501
length of query: 702
length of database: 18,247,518
effective HSP length: 109
effective length of query: 593
effective length of database: 14,120,124
effective search space: 8373233532
effective search space used: 8373233532
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.