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Search of human proteins with 110227626
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110227626 solute carrier family 9 (sodium/hydrogen
exchanger), member 6 isoform a [Homo sapiens]
(701 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)... 1401 0.0
gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ... 1321 0.0
gi|14211919 solute carrier family 9, member 7 [Homo sapiens] 928 0.0
gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),... 765 0.0
gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens] 265 1e-70
gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)... 194 2e-49
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),... 192 9e-49
gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens] 191 2e-48
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ... 189 6e-48
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)... 189 1e-47
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens] 50 7e-06
gi|52487176 tripartite motif-containing 37 protein [Homo sapiens] 35 0.18
gi|15147333 tripartite motif-containing 37 protein [Homo sapiens] 35 0.18
gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming ... 35 0.24
gi|13376856 solute carrier family 19, member 3 [Homo sapiens] 33 0.69
gi|224465231 solute carrier family 9, member 11 [Homo sapiens] 33 1.2
gi|27734871 regulatory factor X, 6 [Homo sapiens] 32 2.6
gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo s... 31 3.4
gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo sa... 31 3.4
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 31 4.5
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 31 4.5
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 31 4.5
gi|164698502 septin 9 isoform d [Homo sapiens] 31 4.5
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 30 5.8
gi|4557373 biotinidase precursor [Homo sapiens] 30 7.6
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 30 7.6
gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens] 30 9.9
>gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger),
member 6 isoform a [Homo sapiens]
Length = 701
Score = 1401 bits (3626), Expect = 0.0
Identities = 701/701 (100%), Positives = 701/701 (100%)
Query: 1 MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60
MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE
Sbjct: 1 MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60
Query: 61 KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI
Sbjct: 61 KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
Query: 121 HVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180
HVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP
Sbjct: 121 HVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180
Query: 181 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 240
EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT
Sbjct: 181 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 240
Query: 241 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 300
GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS
Sbjct: 241 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 300
Query: 301 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 360
SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL
Sbjct: 301 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 360
Query: 361 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 420
ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL
Sbjct: 361 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 420
Query: 421 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 480
AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF
Sbjct: 421 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 480
Query: 481 QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV 540
QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV
Sbjct: 481 QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV 540
Query: 541 GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI 600
GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI
Sbjct: 541 GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI 600
Query: 601 ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA 660
ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA
Sbjct: 601 ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA 660
Query: 661 LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA 701
LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA
Sbjct: 661 LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA 701
>gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
member 6 isoform b [Homo sapiens]
Length = 669
Score = 1321 bits (3418), Expect = 0.0
Identities = 669/701 (95%), Positives = 669/701 (95%), Gaps = 32/701 (4%)
Query: 1 MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60
MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE
Sbjct: 1 MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60
Query: 61 KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI
Sbjct: 61 KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
Query: 121 HVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180
HVPSDVNNVTLSCEVQSSPTTLLV TFDP
Sbjct: 121 HVPSDVNNVTLSCEVQSSPTTLLV--------------------------------TFDP 148
Query: 181 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 240
EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT
Sbjct: 149 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 208
Query: 241 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 300
GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS
Sbjct: 209 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 268
Query: 301 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 360
SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL
Sbjct: 269 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 328
Query: 361 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 420
ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL
Sbjct: 329 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 388
Query: 421 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 480
AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF
Sbjct: 389 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 448
Query: 481 QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV 540
QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV
Sbjct: 449 QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV 508
Query: 541 GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI 600
GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI
Sbjct: 509 GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI 568
Query: 601 ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA 660
ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA
Sbjct: 569 ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA 628
Query: 661 LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA 701
LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA
Sbjct: 629 LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA 669
>gi|14211919 solute carrier family 9, member 7 [Homo sapiens]
Length = 725
Score = 928 bits (2399), Expect = 0.0
Identities = 487/710 (68%), Positives = 561/710 (79%), Gaps = 43/710 (6%)
Query: 18 SPRARRLMRPLWLLLAVGVFDWAGASDGGGG-EARAMDEEIVSEKQAEESHRQDSANLLI 76
+P R L+ PL L + V A AS G E + EE+ +EK+AEESHRQDS +LL
Sbjct: 17 APPPRLLLLPLLLGWGLRVAAAASASSSGAAAEDSSAMEELATEKEAEESHRQDSVSLLT 76
Query: 77 FILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQ 136
FILLLTLTILTIWLFKHRR RFLHETGLAMIYGL+VG++LRYG S + +LSC +
Sbjct: 77 FILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYGTPATSG-RDKSLSCTQE 135
Query: 137 SSP-TTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYA 195
+TLLVNVSGKF+EY LKGEIS ++N+V+ N+MLRKVTFDPEVFFNILLPPIIF+A
Sbjct: 136 DRAFSTLLVNVSGKFFEYTLKGEISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHA 195
Query: 196 GYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLF 255
GYSLK+RHFFRNLGSILAYAFLGTA+SCF+IG++MYG V LMK+ GQL+ FY+TDCL F
Sbjct: 196 GYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFF 255
Query: 256 GAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTF 315
GAI+SATDPVTVLAIF+EL DV+LYALLFGESVLNDAVAIVLSSSIVAYQPAG N+H F
Sbjct: 256 GAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAF 315
Query: 316 DVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLL 375
D A FKS+GIFLGIFSGSF MGA TGV A VTKFTKL F LLET LFFLMSWSTFLL
Sbjct: 316 DAAAFFKSVGIFLGIFSGSFTMGAVTGV-NANVTKFTKLHCFPLLETALFFLMSWSTFLL 374
Query: 376 AEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFT 435
AEA GFTGVVAVLFCGITQAHYTYNNLS ES+ RTKQLFE+L+FLAENFIFSYMGL LFT
Sbjct: 375 AEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFT 434
Query: 436 FQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAF 495
FQ HVF+P F++GAFVAIFLGRAA+IYPLS LNLGRR KIG NFQHMMMF+GLRGAMAF
Sbjct: 435 FQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAF 494
Query: 496 ALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEH------- 548
ALAIRDTA+YARQMMF+TTLLIVFFTVW+ GGGTT MLS L+IRVGV+ E
Sbjct: 495 ALAIRDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGVEEPSEEDQNEHHW 554
Query: 549 ----LGV--------------------PENER-RTTKAESAWLFRMWYNFDHNYLKPLLT 583
+GV P++ R TK ESAW+FR+WY+FDHNYLKP+LT
Sbjct: 555 QYFRVGVDPDQDPPPNNDSFQVLQGDGPDSARGNRTKQESAWIFRLWYSFDHNYLKPILT 614
Query: 584 HSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEP 643
HSGPPLTTTLPA CG +ARCLTSPQ Y+NQE L+++DSD IL +GD++LTYGDSTV
Sbjct: 615 HSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREEDSDFILTEGDLTLTYGDSTVTANG 674
Query: 644 ATSS-------APRRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDS 686
++SS R +SSE+ L+R+L GD ++ RGTRLV P++D+
Sbjct: 675 SSSSHTASTSLEGSRRTKSSSEEVLERDLGMGDQKVSSRGTRLVFPLEDN 724
>gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),
member 9 [Homo sapiens]
Length = 645
Score = 765 bits (1975), Expect = 0.0
Identities = 396/636 (62%), Positives = 486/636 (76%), Gaps = 19/636 (2%)
Query: 57 IVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVL 116
++SEK + Q + LL+F LL LTILTIWLFK+ R RFLHETG AM+YGL++GL+L
Sbjct: 7 VMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLIL 66
Query: 117 RYGIHVPSDVNNVTL--SCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLR 174
RY P+D+ + T+ ++ SP+TLLVN++ + YEY K EIS H +N Q N +L
Sbjct: 67 RYAT-APTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILE 125
Query: 175 KVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCV 234
K+TFDPE+FFN+LLPPIIF+AGYSLK+RHFF+NLGSIL YAFLGTAISC VIG IMYG V
Sbjct: 126 KMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFV 185
Query: 235 TLMKVTGQLA-GDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDA 293
M GQL GDF+FTDCL FG+++SATDPVTVLAIFHEL VD +LY LLFGESVLNDA
Sbjct: 186 KAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDA 245
Query: 294 VAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTK 353
VAIVL+ SI Y P +N + FD A F+S+G FLGIF+GSFAMG+A ++TAL+TKFTK
Sbjct: 246 VAIVLTYSISIYSPK-ENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTK 304
Query: 354 LREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQL 413
L EF +LETGLFFL+SWS FL AEA G TG+VAVLFCG+TQAHYTYNNLS++S+ RTKQL
Sbjct: 305 LCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQL 364
Query: 414 FELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRR 473
FE +NFLAEN IF YMGL LFTFQNH+FN F++GAF+AIF+ RA NIYPLS LLNLGR+
Sbjct: 365 FEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRK 424
Query: 474 SKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAML 533
KI NFQHMMMF+GLRGA+AFALAIR+T + +QMMF+TTLL+VFFTVWVFGGGTT ML
Sbjct: 425 QKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPML 484
Query: 534 SCLHIRVGVDSDQ--------EHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHS 585
+ L IRVGVD D+ +H ++ TKAESA LFRMWY+FDH YLKP+LTHS
Sbjct: 485 TWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHS 544
Query: 586 GPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGD--STVNTEP 643
GPPLTTTLP CGPI+R LTSPQAY EQLK+DD + I+N ++++ Y + S+ + P
Sbjct: 545 GPPLTTTLPEWCGPISRLLTSPQAY--GEQLKEDDVECIVNQDELAINYQEQASSPCSPP 602
Query: 644 ATSSAPRRFMGNS--SEDALDRELAFGDHELVIRGT 677
A ++ + E+ + +L G +EL + T
Sbjct: 603 ARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQT 638
>gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]
Length = 581
Score = 265 bits (676), Expect = 1e-70
Identities = 165/482 (34%), Positives = 258/482 (53%), Gaps = 58/482 (12%)
Query: 61 KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
+QA++ + + +L+L + I+ + L R FL E+ + G+L+G V++
Sbjct: 49 EQAQQEEQSSGMTIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKI-- 106
Query: 121 HVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180
I +L N ++ EM R P
Sbjct: 107 --------------------------------------IEFKKLANWKEEEMFR-----P 123
Query: 181 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 240
+FF +LLPPIIF +GYSL + +FF+N+GSI +A GTAIS FV+G +Y
Sbjct: 124 NMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIY-------FL 176
Query: 241 GQ--LAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVL 298
GQ + TD FG+++SA DPV +AIF+ L VD L L+FGES+LNDAV+IVL
Sbjct: 177 GQADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVL 236
Query: 299 SSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQ 358
+++ + S +++ FL +F GS A+G TG+++ALV K LR+
Sbjct: 237 TNTAEGLTRK-NMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTP 295
Query: 359 LLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLN 418
LE G+ + ++ + LAE +G++A+LF GI +HYT++NLS +Q +Q +
Sbjct: 296 SLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVA 355
Query: 419 FLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGS 478
FL E +F+++GL++F+F H F +FV+ V + GRA NI+PLS LLN R KI
Sbjct: 356 FLCETCVFAFLGLSIFSFP-HKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITP 414
Query: 479 NFQHMMMFAGLRGAMAFALAIR--DTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCL 536
+M F+GLRGA+ +AL++ RQ++ +TT++IV FT+ + GG T ++ +
Sbjct: 415 KMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLM 474
Query: 537 HI 538
I
Sbjct: 475 DI 476
>gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 3 [Homo sapiens]
Length = 834
Score = 194 bits (494), Expect = 2e-49
Identities = 156/514 (30%), Positives = 246/514 (47%), Gaps = 69/514 (13%)
Query: 21 ARRLMRPLWLLLAVGVFDWAGASD--GGGGEARAMDEEIVSEKQAEESHRQDSANLLIFI 78
AR R L L LA+G AG + GG + ++V+ E +H QD + ++I
Sbjct: 6 ARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVT---FEWAHVQDPYVIALWI 62
Query: 79 LLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSS 138
L+ +L + L H+ + E+ L ++ GL++G ++ H+ S
Sbjct: 63 LVASLAKIGFHL-SHKVTSVVPESALLIVLGLVLGGIVWAADHIAS-------------- 107
Query: 139 PTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYS 198
T P VFF LLPPI+ AGY
Sbjct: 108 -------------------------------------FTLTPTVFFFYLLPPIVLDAGYF 130
Query: 199 LKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAI 258
+ R FF NLG+IL YA +GT + G +YG V L + G L D LLFG++
Sbjct: 131 MPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYG-VFLSGLMGDL--QIGLLDFLLFGSL 187
Query: 259 VSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQP-AGDNSHTFDV 317
++A DPV VLA+F E+ V+ L+ ++FGES+LNDAV +VL + ++ GDN D
Sbjct: 188 MAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDC 247
Query: 318 TAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAE 377
K I F + G +G + +LVT+FTK +++E G F++S+ ++L +E
Sbjct: 248 V---KGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTK--HVRIIEPGFVFIISYLSYLTSE 302
Query: 378 AWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQ 437
+ ++A+ FCGI Y N+S +S + ++L AE IF ++G++
Sbjct: 303 MLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPF 362
Query: 438 NHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFAL 497
+N FV+ V I + RA + + LLN R ++ Q ++ + GLRGA+AFAL
Sbjct: 363 IWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFAL 422
Query: 498 AI--RDTATYARQMMFSTTLLIVFFTVWVFGGGT 529
+ + + STT+++VFFTV +F G T
Sbjct: 423 VVLLDGDKVKEKNLFVSTTIIVVFFTV-IFQGLT 455
>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
member 2 [Homo sapiens]
Length = 812
Score = 192 bits (488), Expect = 9e-49
Identities = 128/423 (30%), Positives = 215/423 (50%), Gaps = 28/423 (6%)
Query: 181 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 240
+VFF LLPPI+ AGY + R FF N+G+I YA +GT + IG ++G + ++
Sbjct: 139 DVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFG---ICQIE 195
Query: 241 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 300
D LLFG+++SA DPV VLA+F + V+ +LY L+FGES+LNDAV +VL +
Sbjct: 196 AFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYN 255
Query: 301 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 360
++ T + +F I F + G +G G + A T+FT +++
Sbjct: 256 LFKSF----CQMKTIETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTRFT--HNIRVI 309
Query: 361 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 420
E FL S+ +++ AE + +G++A+ C +T Y N+S +S K ++L+ +
Sbjct: 310 EPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSV 369
Query: 421 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 480
+E IF +MG++ +NH +N FV + RA ++ L+ ++N R +
Sbjct: 370 SETLIFIFMGVST-VGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRTIPLTFKD 428
Query: 481 QHMMMFAGLRGAMAFALA-IRDTATYARQMMFST-TLLIVFFTVWVFGGGTTAMLSCLHI 538
Q ++ + GLRGA+ FAL + A + R+ +F T ++++FFTV++ G ++ L +
Sbjct: 429 QFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDV 488
Query: 539 RVGVDSDQEHLGVPEN------ERRTTKAESA---WLFRMWYN----FDHNYLKPLLTHS 585
+ S+++ V E + T E W W + FD YL+ LL
Sbjct: 489 K---RSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRE 545
Query: 586 GPP 588
P
Sbjct: 546 NQP 548
>gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]
Length = 815
Score = 191 bits (485), Expect = 2e-48
Identities = 132/441 (29%), Positives = 223/441 (50%), Gaps = 51/441 (11%)
Query: 110 LLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQD 169
+L+ +++ G HV ++++ P + L+ V G ++KG +
Sbjct: 109 ILLACLMKIGFHVIPTISSIV--------PESCLLIVVGLLVGGLIKGVGETPPF----- 155
Query: 170 NEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSI 229
+VFF LLPPII AGY L R F NLG+IL +A +GT + F +G +
Sbjct: 156 --------LQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGL 207
Query: 230 MYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESV 289
MY + V G+ + D LLFG+I+SA DPV VLA+F E+ ++ L+ L+FGES+
Sbjct: 208 MYA---VCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESL 264
Query: 290 LNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIG---IFLGIFS------GSFAMGAA 340
LNDAV +VL H F+ A ++ +G IFLG S G +G
Sbjct: 265 LNDAVTVVL-------------YHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVV 311
Query: 341 TGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYN 400
GV+ A ++FT +++E FL S+ +L AE + +G++A++ G+ Y
Sbjct: 312 YGVIAAFTSRFTS--HIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEA 369
Query: 401 NLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAAN 460
N+S +S K ++ + ++E IF ++G++ +H +N TFV+ + + R
Sbjct: 370 NISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHH-WNWTFVISTLLFCLIARVLG 428
Query: 461 IYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALA-IRDTATYARQMMFSTTLL-IV 518
+ L+ +N R K+ Q ++ + GLRGA+AF+L + D + +F T ++ ++
Sbjct: 429 VLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVI 488
Query: 519 FFTVWVFGGGTTAMLSCLHIR 539
FFTV+V G ++ L ++
Sbjct: 489 FFTVFVQGMTIRPLVDLLAVK 509
>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 5 [Homo sapiens]
Length = 896
Score = 189 bits (481), Expect = 6e-48
Identities = 120/350 (34%), Positives = 185/350 (52%), Gaps = 8/350 (2%)
Query: 179 DPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMK 238
+P FF LLPPI+ +GY + R FF NLG+IL YA +GT + F G+ ++G
Sbjct: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162
Query: 239 VTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVL 298
V ++ D LLFG+++SA DPV VLA+F E+ V+ L+ ++FGES+LNDAV +VL
Sbjct: 163 VAPRVQAGLL--DFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVL 220
Query: 299 SSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQ 358
++ G S T K + + G A+G + AL T+FTK +
Sbjct: 221 YKVCNSFVEMG--SANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTK--RVR 276
Query: 359 LLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLN 418
++E L FL++++ +L AE + ++AV CG+ Y N+S +S+ K + L
Sbjct: 277 IIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLA 336
Query: 419 FLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGS 478
AE IF +G++ ++ V+G + I RA + + +LN R +
Sbjct: 337 SCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDK 396
Query: 479 NFQHMMMFAGLRGAMAFALAI--RDTATYARQMMFSTTLLIVFFTVWVFG 526
Q +M + GLRGA+AFAL I T A+ +TT+++VFFTV V G
Sbjct: 397 IDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQG 446
>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
member 4 [Homo sapiens]
Length = 798
Score = 189 bits (479), Expect = 1e-47
Identities = 126/423 (29%), Positives = 219/423 (51%), Gaps = 22/423 (5%)
Query: 179 DPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMK 238
D ++F LLPPI+ GY + R FF N+GSIL +A LG I+ IG +Y + +K
Sbjct: 126 DSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLY-LICQVK 184
Query: 239 VTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVL 298
G GD LLFG+++SA DPV VLA+F E +V+ +LY ++FGE++LND + +VL
Sbjct: 185 AFG--LGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVL 242
Query: 299 SSSIVAYQPAG--DNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLRE 356
+ ++A+ ++ T D+ A F+ + G G G ++A +T+FT +
Sbjct: 243 YNMLIAFTKMHKFEDIETVDILA---GCARFIVVGLGGVLFGIVFGFISAFITRFT--QN 297
Query: 357 FQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFEL 416
+E + F+ S+ ++L AE +G++A+ C +T Y N+S S K ++
Sbjct: 298 ISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKM 357
Query: 417 LNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKI 476
L+ ++E IF +MG++ +NH +N F+ + RA +++ L + N R
Sbjct: 358 LSSVSETLIFIFMGVST-VGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPF 416
Query: 477 GSNFQHMMMFAGLRGAMAFALA-IRDTATYARQMMFST-TLLIVFFTVWVFGGGTTAMLS 534
Q ++ ++G+RGA +F+LA + + + R+ MF T TL++++FTV++ G ++
Sbjct: 417 SIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVR 476
Query: 535 CLHIRV--GVDSDQEHLGVPENERRTTKAESA---W----LFRMWYNFDHNYLKPLLTHS 585
L ++ +S E L + + E W + + FDH YL+ +L
Sbjct: 477 YLDVKKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRK 536
Query: 586 GPP 588
P
Sbjct: 537 NLP 539
>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
Length = 1177
Score = 50.1 bits (118), Expect = 7e-06
Identities = 66/319 (20%), Positives = 128/319 (40%), Gaps = 41/319 (12%)
Query: 180 PEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKV 239
P++FF I P + F + + + IL + G ++ ++ + L+
Sbjct: 76 PDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASVNQLLLK 135
Query: 240 TGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLS 299
T LLF AI+ ++DP+ A +L + L +L+ GES++ ++++
Sbjct: 136 P---------TQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITF 186
Query: 300 SSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREF-- 357
+SI+ + + T + +G SF G++++ + +F F
Sbjct: 187 TSIMDFDQRLQSKRNH--TLAEEIVGGICSYIIASFLF----GILSSKLIQFWMSTVFGD 240
Query: 358 QLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELL 417
+ L F + + F + E G +G+ + G+ N+ S ++ L E
Sbjct: 241 DVNHISLIFSILYLIFYICELVGMSGIFTLAIVGL-----LLNSTSFKAAIEETLLLEFW 295
Query: 418 NFL---AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYP-------LSLL 467
FL A +F++ GL + T++ FV I+ + NIY L+LL
Sbjct: 296 TFLSRIAFLMVFTFFGLLIPAH-------TYLYIEFVDIYY--SLNIYLTLIVLRFLTLL 346
Query: 468 LNLGRRSKIGSNFQHMMMF 486
L S++G F +F
Sbjct: 347 LISPVLSRVGHEFSWRWIF 365
>gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]
Length = 964
Score = 35.4 bits (80), Expect = 0.18
Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 2/64 (3%)
Query: 611 ENQEQLKDDDSDLILNDGDIS--LTYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFG 668
E++E+++++D L+DGD+ L Y D + ++SSA N+ E+ +D E G
Sbjct: 499 EDEEKIQNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSG 558
Query: 669 DHEL 672
++++
Sbjct: 559 ENDV 562
>gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]
Length = 964
Score = 35.4 bits (80), Expect = 0.18
Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 2/64 (3%)
Query: 611 ENQEQLKDDDSDLILNDGDIS--LTYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFG 668
E++E+++++D L+DGD+ L Y D + ++SSA N+ E+ +D E G
Sbjct: 499 EDEEKIQNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSG 558
Query: 669 DHEL 672
++++
Sbjct: 559 ENDV 562
>gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming
sequence b [Homo sapiens]
Length = 982
Score = 35.0 bits (79), Expect = 0.24
Identities = 42/173 (24%), Positives = 69/173 (39%), Gaps = 19/173 (10%)
Query: 537 HIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPA- 595
H RVG D + + ++ R E A +F + Y P PP+TT LP+
Sbjct: 629 HSRVGSDP----VLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSI 684
Query: 596 -CCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTV-NTEPATSSAPRR-- 651
C GP+A L+ +E DDD I + +SL S N +P S
Sbjct: 685 KCTGPLANSLSEKTRDPVEE---DDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHC 741
Query: 652 FMGNSSEDALDRELAFGDHELVIRGTRL-----VLPMDDSEPPLNLLDNTRHG 699
+ + + +++ D + ++G +P+ + PP DN +HG
Sbjct: 742 MLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTR--DNPKHG 792
>gi|13376856 solute carrier family 19, member 3 [Homo sapiens]
Length = 496
Score = 33.5 bits (75), Expect = 0.69
Identities = 53/241 (21%), Positives = 101/241 (41%), Gaps = 49/241 (20%)
Query: 133 CEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNV------QDNEMLRKVTFDPEVF--- 183
CE Q PT+ +++ SGK + KG+++S + +NV Q + L++ +F
Sbjct: 228 CEEQK-PTSEILSTSGK----LNKGQLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWS 282
Query: 184 ---------FNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSI----- 229
FN +L + Y + G++ A A G A++ F +G +
Sbjct: 283 LWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVNWD 342
Query: 230 MYGCVTLMKVTGQLAGDFY-----------FTDCLLFGAIVSATDPVTVLAIFHELQVDV 278
+ G + L+ + AG + + L+F + + V I + ++V
Sbjct: 343 LLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQI--AVNLNV 400
Query: 279 ELYALLFGESVLNDAVAIVLSS--SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFA 336
E YAL+FG +N +A+V+ + +++ G N V+ F G + + +G F
Sbjct: 401 ERYALVFG---INTFIALVIQTIMTVIVVDQRGLN---LPVSIQFLVYGSYFAVIAGIFL 454
Query: 337 M 337
M
Sbjct: 455 M 455
>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
Length = 1124
Score = 32.7 bits (73), Expect = 1.2
Identities = 54/293 (18%), Positives = 113/293 (38%), Gaps = 31/293 (10%)
Query: 143 LVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRR 202
++++SG +M + H++ +LR +F +F+ P IIF ++
Sbjct: 59 ILSLSGFVIGHMAYNSVEVHQIVY----PLLRTSSFSLYSYFS---PLIIFMVALDVEFY 111
Query: 203 HFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSAT 262
+ +L + + + +IG Y + K + L CLLF +
Sbjct: 112 TLKKMFWQVLLTGLISFSTASIIIG---YVVIKFNKDSWDLQS------CLLFSITLGII 162
Query: 263 DPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFK 322
DP+ + + + L+ GES++ ++A + + G+ H +
Sbjct: 163 DPLRSVNSLKTIGISKIYIDLIRGESLIICSIASIFFGNF-----RGNRIHFSIFRDLHV 217
Query: 323 SIGIFLGIFSGSFAMG--AATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWG 380
I + I GS G A + L F+ + L L F M + TF + E G
Sbjct: 218 GIELSYDIL-GSIIFGYWCAKIIQCILADVFSNM----LTNIILCFSMVYMTFYIVEFLG 272
Query: 381 FTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTL 433
+G +A+ G+ T+ + + + + + + E+ I+++ G+ +
Sbjct: 273 MSGTLALAAVGLNLDSLTF---KPKIELVITKFLRIFSSVYEHLIYAFFGIVI 322
>gi|27734871 regulatory factor X, 6 [Homo sapiens]
Length = 928
Score = 31.6 bits (70), Expect = 2.6
Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 607 PQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPAT--SSAPRRFMGNSSEDALDRE 664
P +Y Q +D + LN G + + + AT ++P + G++
Sbjct: 754 PSSYGPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHR 813
Query: 665 LA--FGDHELVIRGTRLVLPMDDSEPPLNLLDNT 696
L H VI R + P D PLN+LD++
Sbjct: 814 LGSMVNQHVSVISSIRSLPPYSDIHDPLNILDDS 847
>gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo
sapiens]
Length = 646
Score = 31.2 bits (69), Expect = 3.4
Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 16/75 (21%)
Query: 322 KSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFF-------LMSWSTFL 374
+S+G+ +G S S + G VTA+ LL +G F + WS++L
Sbjct: 518 QSLGLLIGAASNSLQVATFVGPVTAIPV---------LLFSGFFVSFKTIPTYLQWSSYL 568
Query: 375 LAEAWGFTGVVAVLF 389
+GF GV+ ++
Sbjct: 569 SYVRYGFEGVILTIY 583
>gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo
sapiens]
Length = 646
Score = 31.2 bits (69), Expect = 3.4
Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 16/75 (21%)
Query: 322 KSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFF-------LMSWSTFL 374
+S+G+ +G S S + G VTA+ LL +G F + WS++L
Sbjct: 518 QSLGLLIGAASNSLQVATFVGPVTAIPV---------LLFSGFFVSFKTIPTYLQWSSYL 568
Query: 375 LAEAWGFTGVVAVLF 389
+GF GV+ ++
Sbjct: 569 SYVRYGFEGVILTIY 583
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 30.8 bits (68), Expect = 4.5
Identities = 17/57 (29%), Positives = 24/57 (42%)
Query: 124 SDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180
SD N C+ Q TT L F E + +GE ++N + RK + DP
Sbjct: 1032 SDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEGECQVKKVNKMTSKSKKRKTSIDP 1088
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 30.8 bits (68), Expect = 4.5
Identities = 17/57 (29%), Positives = 24/57 (42%)
Query: 124 SDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180
SD N C+ Q TT L F E + +GE ++N + RK + DP
Sbjct: 1032 SDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEGECQVKKVNKMTSKSKKRKTSIDP 1088
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 30.8 bits (68), Expect = 4.5
Identities = 17/57 (29%), Positives = 24/57 (42%)
Query: 124 SDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180
SD N C+ Q TT L F E + +GE ++N + RK + DP
Sbjct: 1032 SDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEGECQVKKVNKMTSKSKKRKTSIDP 1088
>gi|164698502 septin 9 isoform d [Homo sapiens]
Length = 474
Score = 30.8 bits (68), Expect = 4.5
Identities = 13/24 (54%), Positives = 17/24 (70%)
Query: 1 MARRGWRRAPLRRGVGSSPRARRL 24
+ R GWR+ LRRG G+S R R+L
Sbjct: 55 LGRGGWRQGSLRRGKGTSCRCRQL 78
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 30.4 bits (67), Expect = 5.8
Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 5/116 (4%)
Query: 590 TTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAP 649
TTT P+ PIAR + Y + + L + + + + ++ S ++ +S++
Sbjct: 1525 TTTAPSNSTPIARHPGRTKGYNSDDNLCEPSLEFEVPNHRQYVSRPSSLESSRNTSSNSS 1584
Query: 650 RRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDN-----TRHGP 700
+ SSE R +F +L+ LP + S P N L R+GP
Sbjct: 1585 PLNLKGSSEQLHGRSESFSSEDLIPSRDLATLPREASTPGRNALGRHEYPLPRNGP 1640
>gi|4557373 biotinidase precursor [Homo sapiens]
Length = 543
Score = 30.0 bits (66), Expect = 7.6
Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 11/81 (13%)
Query: 514 TLLIVFFTVWVFGG-----GTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFR 568
TL + + VF G GT + C +R G LG + T+A + F
Sbjct: 432 TLSKELYALGVFDGLHTVHGTYYIQVCALVRCG------GLGFDTCGQEITEATGIFEFH 485
Query: 569 MWYNFDHNYLKPLLTHSGPPL 589
+W NF +Y+ PL SG L
Sbjct: 486 LWGNFSTSYIFPLFLTSGMTL 506
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 30.0 bits (66), Expect = 7.6
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
Query: 585 SGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPA 644
S PP +T P C P AR T P ++ L DD D L +G++ D
Sbjct: 20 SPPPPSTPSPPPCSPDARPAT-PHLLHHRLPLPDDREDGELEEGELE----DDGAEETQD 74
Query: 645 TSSAPRR 651
TS P R
Sbjct: 75 TSGGPER 81
>gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens]
Length = 1040
Score = 29.6 bits (65), Expect = 9.9
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 235 TLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIF 271
T ++ + YFTDC L G + A+ PV VL+ F
Sbjct: 12 TTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLSSF 48
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,730,884
Number of Sequences: 37866
Number of extensions: 1047879
Number of successful extensions: 3305
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3243
Number of HSP's gapped (non-prelim): 31
length of query: 701
length of database: 18,247,518
effective HSP length: 109
effective length of query: 592
effective length of database: 14,120,124
effective search space: 8359113408
effective search space used: 8359113408
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.