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Search of human proteins with 109826564
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109826564 neurofibromin isoform 1 [Homo sapiens]
(2839 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109826564 neurofibromin isoform 1 [Homo sapiens] 5654 0.0
gi|4557793 neurofibromin isoform 2 [Homo sapiens] 5600 0.0
gi|189458804 neurofibromin isoform 3 [Homo sapiens] 1155 0.0
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 107 2e-22
gi|94967023 disabled homolog 2 interacting protein isoform 1 [Ho... 107 2e-22
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens] 105 8e-22
gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens] 105 8e-22
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 103 2e-21
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 103 2e-21
gi|38201692 RAS p21 protein activator 3 [Homo sapiens] 98 1e-19
gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapi... 91 1e-17
gi|12545408 RAS p21 protein activator 2 [Homo sapiens] 89 8e-17
gi|130502162 RAS protein activator like 3 [Homo sapiens] 86 5e-16
gi|4759026 RAS protein activator like 1 [Homo sapiens] 74 2e-12
gi|121114292 RAS p21 protein activator 4 isoform 2 [Homo sapiens] 71 2e-11
gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens] 71 2e-11
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 69 9e-11
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva... 69 9e-11
gi|239508992 PREDICTED: similar to calcium-promoted Ras inactiva... 69 9e-11
gi|239508990 PREDICTED: similar to calcium-promoted Ras inactiva... 69 9e-11
gi|116089337 IQ motif containing GTPase activating protein 2 [Ho... 67 3e-10
gi|4506787 IQ motif containing GTPase activating protein 1 [Homo... 66 6e-10
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 59 5e-08
gi|207450721 ganglioside induced differentiation associated prot... 40 0.025
gi|8923143 ganglioside induced differentiation associated protei... 39 0.056
gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo s... 38 0.16
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13... 34 2.4
gi|117606355 furry homolog [Homo sapiens] 33 3.1
gi|119874201 furry-like [Homo sapiens] 33 4.0
gi|66529407 tensin [Homo sapiens] 33 4.0
>gi|109826564 neurofibromin isoform 1 [Homo sapiens]
Length = 2839
Score = 5654 bits (14667), Expect = 0.0
Identities = 2839/2839 (100%), Positives = 2839/2839 (100%)
Query: 1 MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT 60
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
Sbjct: 1 MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT 60
Query: 61 ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF 120
ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
Sbjct: 61 ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF 120
Query: 121 LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL 180
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
Sbjct: 121 LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL 180
Query: 181 QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT 240
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
Sbjct: 181 QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT 240
Query: 241 DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL 300
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL
Sbjct: 241 DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL 300
Query: 301 DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP 360
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
Sbjct: 301 DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP 360
Query: 361 SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN 420
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
Sbjct: 361 SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN 420
Query: 421 SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK 480
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK
Sbjct: 421 SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK 480
Query: 481 PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE 540
PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
Sbjct: 481 PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE 540
Query: 541 IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL 600
IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL
Sbjct: 541 IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL 600
Query: 601 REILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRK 660
REILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRK
Sbjct: 601 REILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRK 660
Query: 661 GKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIR 720
GKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIR
Sbjct: 661 GKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIR 720
Query: 721 CGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDT 780
CGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDT
Sbjct: 721 CGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDT 780
Query: 781 HAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINM 840
HAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINM
Sbjct: 781 HAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINM 840
Query: 841 TGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLS 900
TGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLS
Sbjct: 841 TGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLS 900
Query: 901 LMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQF 960
LMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQF
Sbjct: 901 LMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQF 960
Query: 961 VEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVE 1020
VEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVE
Sbjct: 961 VEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVE 1020
Query: 1021 VMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLL 1080
VMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLL
Sbjct: 1021 VMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLL 1080
Query: 1081 AGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLAS 1140
AGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLAS
Sbjct: 1081 AGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLAS 1140
Query: 1141 LRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETV 1200
LRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETV
Sbjct: 1141 LRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETV 1200
Query: 1201 LADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNM 1260
LADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNM
Sbjct: 1201 LADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNM 1260
Query: 1261 FSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFE 1320
FSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFE
Sbjct: 1261 FSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFE 1320
Query: 1321 VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKA 1380
VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKA
Sbjct: 1321 VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKA 1380
Query: 1381 TVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK 1440
TVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK
Sbjct: 1381 TVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK 1440
Query: 1441 LMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS 1500
LMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS
Sbjct: 1441 LMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS 1500
Query: 1501 DGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWS 1560
DGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWS
Sbjct: 1501 DGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWS 1560
Query: 1561 SLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQING 1620
SLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQING
Sbjct: 1561 SLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQING 1620
Query: 1621 DLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIY 1680
DLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIY
Sbjct: 1621 DLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIY 1680
Query: 1681 NCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVF 1740
NCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVF
Sbjct: 1681 NCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVF 1740
Query: 1741 HNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFT 1800
HNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFT
Sbjct: 1741 HNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFT 1800
Query: 1801 LTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALL 1860
LTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALL
Sbjct: 1801 LTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALL 1860
Query: 1861 NLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEP 1920
NLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEP
Sbjct: 1861 NLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEP 1920
Query: 1921 HLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLIT 1980
HLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLIT
Sbjct: 1921 HLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLIT 1980
Query: 1981 MTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALAS 2040
MTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALAS
Sbjct: 1981 MTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALAS 2040
Query: 2041 GNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHL 2100
GNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHL
Sbjct: 2041 GNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHL 2100
Query: 2101 PYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPK 2160
PYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPK
Sbjct: 2101 PYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPK 2160
Query: 2161 FYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDI 2220
FYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDI
Sbjct: 2161 FYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDI 2220
Query: 2221 PTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLK 2280
PTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLK
Sbjct: 2221 PTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLK 2280
Query: 2281 GPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQ 2340
GPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQ
Sbjct: 2281 GPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQ 2340
Query: 2341 NLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRH 2400
NLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRH
Sbjct: 2341 NLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRH 2400
Query: 2401 PSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKS 2460
PSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKS
Sbjct: 2401 PSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKS 2460
Query: 2461 LLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARK 2520
LLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARK
Sbjct: 2461 LLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARK 2520
Query: 2521 SMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEME 2580
SMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEME
Sbjct: 2521 SMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEME 2580
Query: 2581 TQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILY 2640
TQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILY
Sbjct: 2581 TQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILY 2640
Query: 2641 EYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQT 2700
EYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQT
Sbjct: 2641 EYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQT 2700
Query: 2701 SYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTS 2760
SYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTS
Sbjct: 2701 SYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTS 2760
Query: 2761 PYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQ 2820
PYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQ
Sbjct: 2761 PYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQ 2820
Query: 2821 VQKQRSAGSFKRNSIKKIV 2839
VQKQRSAGSFKRNSIKKIV
Sbjct: 2821 VQKQRSAGSFKRNSIKKIV 2839
>gi|4557793 neurofibromin isoform 2 [Homo sapiens]
Length = 2818
Score = 5600 bits (14528), Expect = 0.0
Identities = 2818/2839 (99%), Positives = 2818/2839 (99%), Gaps = 21/2839 (0%)
Query: 1 MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT 60
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
Sbjct: 1 MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT 60
Query: 61 ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF 120
ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
Sbjct: 61 ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF 120
Query: 121 LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL 180
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
Sbjct: 121 LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL 180
Query: 181 QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT 240
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
Sbjct: 181 QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT 240
Query: 241 DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL 300
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL
Sbjct: 241 DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL 300
Query: 301 DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP 360
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
Sbjct: 301 DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP 360
Query: 361 SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN 420
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
Sbjct: 361 SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN 420
Query: 421 SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK 480
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK
Sbjct: 421 SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK 480
Query: 481 PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE 540
PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
Sbjct: 481 PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE 540
Query: 541 IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL 600
IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL
Sbjct: 541 IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL 600
Query: 601 REILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRK 660
REILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRK
Sbjct: 601 REILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRK 660
Query: 661 GKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIR 720
GKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIR
Sbjct: 661 GKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIR 720
Query: 721 CGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDT 780
CGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDT
Sbjct: 721 CGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDT 780
Query: 781 HAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINM 840
HAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINM
Sbjct: 781 HAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINM 840
Query: 841 TGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLS 900
TGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLS
Sbjct: 841 TGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLS 900
Query: 901 LMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQF 960
LMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQF
Sbjct: 901 LMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQF 960
Query: 961 VEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVE 1020
VEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVE
Sbjct: 961 VEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVE 1020
Query: 1021 VMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLL 1080
VMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLL
Sbjct: 1021 VMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLL 1080
Query: 1081 AGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLAS 1140
AGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLAS
Sbjct: 1081 AGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLAS 1140
Query: 1141 LRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETV 1200
LRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETV
Sbjct: 1141 LRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETV 1200
Query: 1201 LADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNM 1260
LADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNM
Sbjct: 1201 LADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNM 1260
Query: 1261 FSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFE 1320
FSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFE
Sbjct: 1261 FSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFE 1320
Query: 1321 VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKA 1380
VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQ
Sbjct: 1321 VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQ---------- 1370
Query: 1381 TVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK 1440
VVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK
Sbjct: 1371 -----------VVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK 1419
Query: 1441 LMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS 1500
LMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS
Sbjct: 1420 LMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS 1479
Query: 1501 DGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWS 1560
DGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWS
Sbjct: 1480 DGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWS 1539
Query: 1561 SLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQING 1620
SLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQING
Sbjct: 1540 SLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQING 1599
Query: 1621 DLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIY 1680
DLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIY
Sbjct: 1600 DLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIY 1659
Query: 1681 NCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVF 1740
NCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVF
Sbjct: 1660 NCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVF 1719
Query: 1741 HNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFT 1800
HNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFT
Sbjct: 1720 HNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFT 1779
Query: 1801 LTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALL 1860
LTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALL
Sbjct: 1780 LTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALL 1839
Query: 1861 NLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEP 1920
NLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEP
Sbjct: 1840 NLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEP 1899
Query: 1921 HLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLIT 1980
HLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLIT
Sbjct: 1900 HLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLIT 1959
Query: 1981 MTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALAS 2040
MTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALAS
Sbjct: 1960 MTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALAS 2019
Query: 2041 GNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHL 2100
GNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHL
Sbjct: 2020 GNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHL 2079
Query: 2101 PYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPK 2160
PYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPK
Sbjct: 2080 PYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPK 2139
Query: 2161 FYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDI 2220
FYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDI
Sbjct: 2140 FYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDI 2199
Query: 2221 PTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLK 2280
PTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLK
Sbjct: 2200 PTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLK 2259
Query: 2281 GPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQ 2340
GPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQ
Sbjct: 2260 GPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQ 2319
Query: 2341 NLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRH 2400
NLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRH
Sbjct: 2320 NLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRH 2379
Query: 2401 PSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKS 2460
PSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKS
Sbjct: 2380 PSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKS 2439
Query: 2461 LLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARK 2520
LLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARK
Sbjct: 2440 LLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARK 2499
Query: 2521 SMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEME 2580
SMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEME
Sbjct: 2500 SMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEME 2559
Query: 2581 TQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILY 2640
TQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILY
Sbjct: 2560 TQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILY 2619
Query: 2641 EYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQT 2700
EYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQT
Sbjct: 2620 EYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQT 2679
Query: 2701 SYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTS 2760
SYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTS
Sbjct: 2680 SYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTS 2739
Query: 2761 PYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQ 2820
PYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQ
Sbjct: 2740 PYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQ 2799
Query: 2821 VQKQRSAGSFKRNSIKKIV 2839
VQKQRSAGSFKRNSIKKIV
Sbjct: 2800 VQKQRSAGSFKRNSIKKIV 2818
>gi|189458804 neurofibromin isoform 3 [Homo sapiens]
Length = 593
Score = 1155 bits (2987), Expect = 0.0
Identities = 573/581 (98%), Positives = 576/581 (99%)
Query: 1 MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT 60
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
Sbjct: 1 MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT 60
Query: 61 ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF 120
ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
Sbjct: 61 ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF 120
Query: 121 LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL 180
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
Sbjct: 121 LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL 180
Query: 181 QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT 240
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
Sbjct: 181 QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT 240
Query: 241 DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL 300
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL
Sbjct: 241 DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL 300
Query: 301 DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP 360
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
Sbjct: 301 DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP 360
Query: 361 SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN 420
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
Sbjct: 361 SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN 420
Query: 421 SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK 480
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK
Sbjct: 421 SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK 480
Query: 481 PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE 540
PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
Sbjct: 481 PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE 540
Query: 541 IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYI 581
IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEI +++
Sbjct: 541 IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEIRYMYFYFL 581
>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
sapiens]
Length = 1065
Score = 107 bits (266), Expect = 2e-22
Identities = 88/307 (28%), Positives = 150/307 (48%), Gaps = 29/307 (9%)
Query: 1221 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVE-LADSMQTLFRGNS 1279
L + AL ++ +E+A LV + S + L ++ EV+ D+ +FR N+
Sbjct: 233 LGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENT 292
Query: 1280 LASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNL 1339
LA+K + K+ G YLQ L ++ + S + + EVDP++ ++ L E+Q NL
Sbjct: 293 LATKAIEEYLKLVGQKYLQDALGEFIKALYESDE----NCEVDPSKCSAAD-LPEHQGNL 347
Query: 1340 LQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQ 1399
E F II+S FP +L+ V ++ C S + +S+R
Sbjct: 348 KMCCELAFCKIINSYCVFPRELKEV-FASWRQECSS------------RGRPDISERL-- 392
Query: 1400 NSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKE 1458
+ +++FLRF+ PAI+SP +L + P R R L L++K+ Q++AN F +KE
Sbjct: 393 -----ISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKE 447
Query: 1459 EHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVL-ALHRLLWNNQEK 1517
E+M N F++ + +RF L+I++ S+ +I G L +LH LLW +
Sbjct: 448 EYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFE-GYIDLGRELSSLHSLLWEAVSQ 506
Query: 1518 IGQYLSS 1524
+ Q + S
Sbjct: 507 LEQSIVS 513
>gi|94967023 disabled homolog 2 interacting protein isoform 1 [Homo
sapiens]
Length = 1132
Score = 107 bits (266), Expect = 2e-22
Identities = 88/307 (28%), Positives = 150/307 (48%), Gaps = 29/307 (9%)
Query: 1221 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVE-LADSMQTLFRGNS 1279
L + AL ++ +E+A LV + S + L ++ EV+ D+ +FR N+
Sbjct: 329 LGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENT 388
Query: 1280 LASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNL 1339
LA+K + K+ G YLQ L ++ + S + + EVDP++ ++ L E+Q NL
Sbjct: 389 LATKAIEEYLKLVGQKYLQDALGEFIKALYESDE----NCEVDPSKCSAAD-LPEHQGNL 443
Query: 1340 LQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQ 1399
E F II+S FP +L+ V ++ C S + +S+R
Sbjct: 444 KMCCELAFCKIINSYCVFPRELKEV-FASWRQECSS------------RGRPDISERL-- 488
Query: 1400 NSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKE 1458
+ +++FLRF+ PAI+SP +L + P R R L L++K+ Q++AN F +KE
Sbjct: 489 -----ISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKE 543
Query: 1459 EHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVL-ALHRLLWNNQEK 1517
E+M N F++ + +RF L+I++ S+ +I G L +LH LLW +
Sbjct: 544 EYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFE-GYIDLGRELSSLHSLLWEAVSQ 602
Query: 1518 IGQYLSS 1524
+ Q + S
Sbjct: 603 LEQSIVS 609
>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
Length = 1047
Score = 105 bits (261), Expect = 8e-22
Identities = 89/312 (28%), Positives = 147/312 (47%), Gaps = 30/312 (9%)
Query: 1218 QGELPIAMALANVVPCSQWDEL-ARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFR 1276
Q EL + AL++V C Q L A +L+ +F L LL + +E+ + D TLFR
Sbjct: 732 QKELHVVYALSHV--CGQDRTLLASILLRIFLHEKLESLLLCTLNDREISMEDEATTLFR 789
Query: 1277 GNSLASKIMTFCFKVYGATYLQKLL-DPLLRIVITSSDWQHVSFEVDPTRLEPSESLEEN 1335
+LAS +M K ++ L D +L+I+ + S E+ P++LE +E + N
Sbjct: 790 ATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQ-----SCELSPSKLEKNEDVNTN 844
Query: 1336 QRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQ 1395
+LL + + I +S PP LR + CL ++ H T++ +
Sbjct: 845 LTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTR---------- 894
Query: 1396 RFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF 1455
V +FLR I PAI++P I+ P P R L L++K +Q++AN V F
Sbjct: 895 --------VVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEF 946
Query: 1456 -TKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNN 1514
KE +M N F+KSN F ++ + D HS + +S ++ ALH + +
Sbjct: 947 GAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRTDLS-RDLAALHEICVAH 1005
Query: 1515 QEKIGQYLSSNR 1526
+++ + LS+ R
Sbjct: 1006 SDEL-RTLSNER 1016
>gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens]
Length = 870
Score = 105 bits (261), Expect = 8e-22
Identities = 89/312 (28%), Positives = 147/312 (47%), Gaps = 30/312 (9%)
Query: 1218 QGELPIAMALANVVPCSQWDEL-ARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFR 1276
Q EL + AL++V C Q L A +L+ +F L LL + +E+ + D TLFR
Sbjct: 555 QKELHVVYALSHV--CGQDRTLLASILLRIFLHEKLESLLLCTLNDREISMEDEATTLFR 612
Query: 1277 GNSLASKIMTFCFKVYGATYLQKLL-DPLLRIVITSSDWQHVSFEVDPTRLEPSESLEEN 1335
+LAS +M K ++ L D +L+I+ + S E+ P++LE +E + N
Sbjct: 613 ATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQ-----SCELSPSKLEKNEDVNTN 667
Query: 1336 QRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQ 1395
+LL + + I +S PP LR + CL ++ H T++ +
Sbjct: 668 LTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTR---------- 717
Query: 1396 RFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF 1455
V +FLR I PAI++P I+ P P R L L++K +Q++AN V F
Sbjct: 718 --------VVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEF 769
Query: 1456 -TKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNN 1514
KE +M N F+KSN F ++ + D HS + +S ++ ALH + +
Sbjct: 770 GAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRTDLS-RDLAALHEICVAH 828
Query: 1515 QEKIGQYLSSNR 1526
+++ + LS+ R
Sbjct: 829 SDEL-RTLSNER 839
>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
Length = 1280
Score = 103 bits (258), Expect = 2e-21
Identities = 89/313 (28%), Positives = 148/313 (47%), Gaps = 33/313 (10%)
Query: 1203 DRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFS 1262
++++ E VT + L V+ +ELA LV + S L ++
Sbjct: 447 EQYKEFAEFVT----SNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVM 502
Query: 1263 KEVELADSMQTL-FRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEV 1321
EV+ L FR N++A+K + K+ G YL L ++ + S + + EV
Sbjct: 503 SEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDE----NCEV 558
Query: 1322 DPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKAT 1381
DP++ SE L ++Q NL E F II+S FP +L+ V + + LN+
Sbjct: 559 DPSKCSSSE-LIDHQSNLKMCCELAFCKIINSYCVFPRELKEV----FASWKQQCLNRG- 612
Query: 1382 VKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKL 1441
K +S+R + +++FLRF+ PAI+SP ++ + P R R L L
Sbjct: 613 --------KQDISERL-------ISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTL 657
Query: 1442 MSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS 1500
++K++Q++AN F KEE+M NDF++ + +RF L+I++ S+ +I
Sbjct: 658 IAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFD-GYID 716
Query: 1501 DGNVLA-LHRLLW 1512
G L+ LH LLW
Sbjct: 717 LGRELSVLHSLLW 729
>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
Length = 1139
Score = 103 bits (258), Expect = 2e-21
Identities = 89/313 (28%), Positives = 148/313 (47%), Gaps = 33/313 (10%)
Query: 1203 DRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFS 1262
++++ E VT + L V+ +ELA LV + S L ++
Sbjct: 299 EQYKEFAEFVT----SNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVM 354
Query: 1263 KEVELADSMQTL-FRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEV 1321
EV+ L FR N++A+K + K+ G YL L ++ + S + + EV
Sbjct: 355 SEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDE----NCEV 410
Query: 1322 DPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKAT 1381
DP++ SE L ++Q NL E F II+S FP +L+ V + + LN+
Sbjct: 411 DPSKCSSSE-LIDHQSNLKMCCELAFCKIINSYCVFPRELKEV----FASWKQQCLNRG- 464
Query: 1382 VKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKL 1441
K +S+R + +++FLRF+ PAI+SP ++ + P R R L L
Sbjct: 465 --------KQDISERL-------ISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTL 509
Query: 1442 MSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS 1500
++K++Q++AN F KEE+M NDF++ + +RF L+I++ S+ +I
Sbjct: 510 IAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFD-GYID 568
Query: 1501 DGNVLA-LHRLLW 1512
G L+ LH LLW
Sbjct: 569 LGRELSVLHSLLW 581
>gi|38201692 RAS p21 protein activator 3 [Homo sapiens]
Length = 834
Score = 98.2 bits (243), Expect = 1e-19
Identities = 82/276 (29%), Positives = 125/276 (45%), Gaps = 29/276 (10%)
Query: 1222 PIAMALANVVP--CSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNS 1279
P++ + A+++ C + E A LV LF + + + S EV+ T+FRGNS
Sbjct: 315 PVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNS 374
Query: 1280 LASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNL 1339
LASK + K+ G YL L P + + S H E+DP +L+ E+LE N NL
Sbjct: 375 LASKCIDETMKLAGMHYLHVTLKPAIEEICQS----HKPCEIDPVKLKDGENLENNMENL 430
Query: 1340 LQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQ 1399
Q ++ FHAI S P + C + L +A K +++ P
Sbjct: 431 RQYVDRVFHAITESGVSCPTVM---CDIFFS------LREAAAKRFQDD---------PD 472
Query: 1400 NSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIA----NHVLF 1455
AV S +FLRF PAI+SP + P+ R L L+SK +Q++ +
Sbjct: 473 VRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSAS 532
Query: 1456 TKEEHMRPFNDFV-KSNFDAARRFFLDIASDCPTSD 1490
KE +M F +F + + A + FLD+ S D
Sbjct: 533 FKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRD 568
>gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapiens]
Length = 1343
Score = 91.3 bits (225), Expect = 1e-17
Identities = 78/282 (27%), Positives = 139/282 (49%), Gaps = 35/282 (12%)
Query: 1237 DELARVLVTLFDSRHLLYQLLWNMFSKEVE-LADSMQTLFRGNSLASKIMTFCFKVYGAT 1295
+E+A LV + S L +M EV+ + +FR N+LA+K + ++ G
Sbjct: 445 EEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQK 504
Query: 1296 YLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSS 1355
YL+ + +R + S + + EVDP + S SL E+Q NL E +++S
Sbjct: 505 YLKDAIGEFIRALYESEE----NCEVDPIKCTAS-SLAEHQANLRMCCELALCKVVNSHC 559
Query: 1356 EFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFIN 1415
FP +L+ V ++ C E + ++ R + +++FLRF+
Sbjct: 560 VFPRELKEV-FASWRLRC------------AERGREDIADRL-------ISASLFLRFLC 599
Query: 1416 PAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFT-KEEHMRPFNDFVKSNFDA 1474
PAI+SP G++ + P + R L L++K++Q++AN FT KE+ + N+F++ + +
Sbjct: 600 PAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGS 659
Query: 1475 ARRFFLDIASDCPTSDAVNHSLSF---ISDGNVLA-LHRLLW 1512
++F +I++ D + +S SF I G L+ LH LLW
Sbjct: 660 MQQFLYEISN----LDTLTNSSSFEGYIDLGRELSTLHALLW 697
>gi|12545408 RAS p21 protein activator 2 [Homo sapiens]
Length = 849
Score = 88.6 bits (218), Expect = 8e-17
Identities = 68/240 (28%), Positives = 112/240 (46%), Gaps = 37/240 (15%)
Query: 1264 EVELADSMQ--TLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEV 1321
E++L D+ T+FRGNSLA++ + K+ G YL+ L P+L + SS S E+
Sbjct: 383 ELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICDSSK----SCEI 438
Query: 1322 DPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKAT 1381
DP +L+ +++E N+ NL +K F+ I+ SS P + + + L Q
Sbjct: 439 DPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQ----------- 487
Query: 1382 VKEKKENKKSVVSQRFPQN---SIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG 1438
+ +QRFP + AV S +FLRF A+VSP+ + P + R
Sbjct: 488 ----------MATQRFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRT 537
Query: 1439 LKLMSKILQSIANHVLFTKEEH-------MRPFNDFVKSNFDAARRFFLDIASDCPTSDA 1491
L L+SK +Q++ + +K + F F + + A + FLD S T ++
Sbjct: 538 LTLISKTIQTLGSWGSLSKSKSSFKETFMCEFFKMFQEEGYIIAVKKFLDEISSTETKES 597
>gi|130502162 RAS protein activator like 3 [Homo sapiens]
Length = 1011
Score = 85.9 bits (211), Expect = 5e-16
Identities = 76/284 (26%), Positives = 133/284 (46%), Gaps = 31/284 (10%)
Query: 1202 ADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMF 1261
++R++ L E +T + + AL +P +ELA +V + + L+ ++
Sbjct: 429 SERYKELAEFLTFHYAR----LCGALEPALPAQAKEELAAAMVRVLRATGRAQALVTDLG 484
Query: 1262 SKEVELADSMQTL-FRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFE 1320
+ E+ + L FR N+LA+K + K+ YLQ+ L ++R + S++ E
Sbjct: 485 TAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTE----DCE 540
Query: 1321 VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKA 1380
VDP++ P+ L E+Q L E+ F II S FP +L + ++ C
Sbjct: 541 VDPSKC-PASELPEHQARLRNSCEEVFETIIHSYDWFPAEL-GIVFSSWREAC------- 591
Query: 1381 TVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK 1440
KE V+ R V +++FLR + PAI++P G+ P P R L
Sbjct: 592 -----KERGSEVLGPRL-------VCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLT 639
Query: 1441 LMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARRFFLDIA 1483
L++K++Q++AN F KE +M N F++ + A + F +A
Sbjct: 640 LIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVA 683
>gi|4759026 RAS protein activator like 1 [Homo sapiens]
Length = 804
Score = 74.3 bits (181), Expect = 2e-12
Identities = 74/263 (28%), Positives = 106/263 (40%), Gaps = 47/263 (17%)
Query: 1238 ELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYL 1297
+LA LV LF R L L + +EV TLFR NSLASK M K+ G YL
Sbjct: 304 DLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGMPYL 363
Query: 1298 QKLLDPLLRIVITSSDWQHVSFEVDPTRLE-------------PSESLEENQRNLLQ-MT 1343
++L P++ V + E+DP +++ E + E LL
Sbjct: 364 HEVLKPVISRVFEEKKY----MELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYL 419
Query: 1344 EKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQN--- 1400
AI+ S PP +R L++ V +RFPQ
Sbjct: 420 GPIVDAIVGSVGRCPPAMRLAFKQLHRR---------------------VEERFPQAEHQ 458
Query: 1401 --SIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIAN---HVLF 1455
A+ +FLRF PAI++P + D+ P+ R L L++K +QSI N +
Sbjct: 459 DVKYLAISGFLFLRFFAPAILTPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQ 518
Query: 1456 TKEEHMRPFNDFVKSNFDAARRF 1478
KE M P + F+ R F
Sbjct: 519 GKELWMAPLHPFLLQCVSRVRDF 541
>gi|121114292 RAS p21 protein activator 4 isoform 2 [Homo sapiens]
Length = 757
Score = 70.9 bits (172), Expect = 2e-11
Identities = 75/299 (25%), Positives = 123/299 (41%), Gaps = 35/299 (11%)
Query: 1198 ETVL-ADRFERLVELV---TMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLL 1253
ETVL + ++ LV L+ +G QG + + ++A L+ LF + L
Sbjct: 261 ETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLA 320
Query: 1254 YQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSD 1313
L +F E+ TLFR NSLASK M KV G YL +L P++ V
Sbjct: 321 KDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQYLHGVLGPIINKVFEEKK 380
Query: 1314 WQHVSFEVDPTRLEPSE------SLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHC 1367
+ E+DP+++E + + + +L+ + + A + + + C
Sbjct: 381 Y----VELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPA 436
Query: 1368 LYQATCHSLLNKATVKEKKENKKSVVSQRFP-----QNSIGAVGSAMFLRFINPAIVSPY 1422
+ +AT L + V +RFP AV S + LRF +PAI+SP
Sbjct: 437 VVRATFRQLFRR-------------VRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPK 483
Query: 1423 EAGILDKKPPPRIERGLKLMSKILQSIAN---HVLFTKEEHMRPFNDFVKSNFDAARRF 1478
+ ++ R R L L++K +Q++ N KE M P V+ + F
Sbjct: 484 LFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDF 542
>gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens]
Length = 803
Score = 70.9 bits (172), Expect = 2e-11
Identities = 75/299 (25%), Positives = 123/299 (41%), Gaps = 35/299 (11%)
Query: 1198 ETVL-ADRFERLVELV---TMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLL 1253
ETVL + ++ LV L+ +G QG + + ++A L+ LF + L
Sbjct: 261 ETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLA 320
Query: 1254 YQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSD 1313
L +F E+ TLFR NSLASK M KV G YL +L P++ V
Sbjct: 321 KDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQYLHGVLGPIINKVFEEKK 380
Query: 1314 WQHVSFEVDPTRLEPSE------SLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHC 1367
+ E+DP+++E + + + +L+ + + A + + + C
Sbjct: 381 Y----VELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPA 436
Query: 1368 LYQATCHSLLNKATVKEKKENKKSVVSQRFP-----QNSIGAVGSAMFLRFINPAIVSPY 1422
+ +AT L + V +RFP AV S + LRF +PAI+SP
Sbjct: 437 VVRATFRQLFRR-------------VRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPK 483
Query: 1423 EAGILDKKPPPRIERGLKLMSKILQSIAN---HVLFTKEEHMRPFNDFVKSNFDAARRF 1478
+ ++ R R L L++K +Q++ N KE M P V+ + F
Sbjct: 484 LFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDF 542
>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 731
Score = 68.6 bits (166), Expect = 9e-11
Identities = 68/269 (25%), Positives = 115/269 (42%), Gaps = 32/269 (11%)
Query: 1198 ETVL-ADRFERLVELV---TMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLL 1253
ETVL + ++ LV L+ +G QG + + ++A L+ LF + L
Sbjct: 189 ETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLA 248
Query: 1254 YQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSD 1313
L +F E+ TLFR NSLASK + KV G YL +L P++ V
Sbjct: 249 KDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPIINKVFEEKK 308
Query: 1314 WQHVSFEVDPTRLEPSE------SLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHC 1367
+ E+DP+++E + + + +L+ + + A + + + C
Sbjct: 309 Y----VELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPA 364
Query: 1368 LYQATCHSLLNKATVKEKKENKKSVVSQRFP-----QNSIGAVGSAMFLRFINPAIVSPY 1422
+ +AT L + V +RFP AV S + LRF +PAI+SP
Sbjct: 365 VVRATFRQLFRR-------------VRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPK 411
Query: 1423 EAGILDKKPPPRIERGLKLMSKILQSIAN 1451
+ ++ R R L L++K +Q++ N
Sbjct: 412 LFHLRERHADARTSRTLLLLAKAVQNVGN 440
>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 757
Score = 68.6 bits (166), Expect = 9e-11
Identities = 68/269 (25%), Positives = 115/269 (42%), Gaps = 32/269 (11%)
Query: 1198 ETVL-ADRFERLVELV---TMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLL 1253
ETVL + ++ LV L+ +G QG + + ++A L+ LF + L
Sbjct: 261 ETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLA 320
Query: 1254 YQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSD 1313
L +F E+ TLFR NSLASK + KV G YL +L P++ V
Sbjct: 321 KDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPIINKVFEEKK 380
Query: 1314 WQHVSFEVDPTRLEPSE------SLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHC 1367
+ E+DP+++E + + + +L+ + + A + + + C
Sbjct: 381 Y----VELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPA 436
Query: 1368 LYQATCHSLLNKATVKEKKENKKSVVSQRFP-----QNSIGAVGSAMFLRFINPAIVSPY 1422
+ +AT L + V +RFP AV S + LRF +PAI+SP
Sbjct: 437 VVRATFRQLFRR-------------VRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPK 483
Query: 1423 EAGILDKKPPPRIERGLKLMSKILQSIAN 1451
+ ++ R R L L++K +Q++ N
Sbjct: 484 LFHLRERHADARTSRTLLLLAKAVQNVGN 512
>gi|239508992 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 731
Score = 68.6 bits (166), Expect = 9e-11
Identities = 68/269 (25%), Positives = 115/269 (42%), Gaps = 32/269 (11%)
Query: 1198 ETVL-ADRFERLVELV---TMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLL 1253
ETVL + ++ LV L+ +G QG + + ++A L+ LF + L
Sbjct: 189 ETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLA 248
Query: 1254 YQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSD 1313
L +F E+ TLFR NSLASK + KV G YL +L P++ V
Sbjct: 249 KDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPIINKVFEEKK 308
Query: 1314 WQHVSFEVDPTRLEPSE------SLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHC 1367
+ E+DP+++E + + + +L+ + + A + + + C
Sbjct: 309 Y----VELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPA 364
Query: 1368 LYQATCHSLLNKATVKEKKENKKSVVSQRFP-----QNSIGAVGSAMFLRFINPAIVSPY 1422
+ +AT L + V +RFP AV S + LRF +PAI+SP
Sbjct: 365 VVRATFRQLFRR-------------VRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPK 411
Query: 1423 EAGILDKKPPPRIERGLKLMSKILQSIAN 1451
+ ++ R R L L++K +Q++ N
Sbjct: 412 LFHLRERHADARTSRTLLLLAKAVQNVGN 440
>gi|239508990 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 757
Score = 68.6 bits (166), Expect = 9e-11
Identities = 68/269 (25%), Positives = 115/269 (42%), Gaps = 32/269 (11%)
Query: 1198 ETVL-ADRFERLVELV---TMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLL 1253
ETVL + ++ LV L+ +G QG + + ++A L+ LF + L
Sbjct: 261 ETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLA 320
Query: 1254 YQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSD 1313
L +F E+ TLFR NSLASK + KV G YL +L P++ V
Sbjct: 321 KDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPIINKVFEEKK 380
Query: 1314 WQHVSFEVDPTRLEPSE------SLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHC 1367
+ E+DP+++E + + + +L+ + + A + + + C
Sbjct: 381 Y----VELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPA 436
Query: 1368 LYQATCHSLLNKATVKEKKENKKSVVSQRFP-----QNSIGAVGSAMFLRFINPAIVSPY 1422
+ +AT L + V +RFP AV S + LRF +PAI+SP
Sbjct: 437 VVRATFRQLFRR-------------VRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPK 483
Query: 1423 EAGILDKKPPPRIERGLKLMSKILQSIAN 1451
+ ++ R R L L++K +Q++ N
Sbjct: 484 LFHLRERHADARTSRTLLLLAKAVQNVGN 512
>gi|116089337 IQ motif containing GTPase activating protein 2 [Homo
sapiens]
Length = 1575
Score = 67.0 bits (162), Expect = 3e-10
Identities = 77/334 (23%), Positives = 142/334 (42%), Gaps = 79/334 (23%)
Query: 1242 VLVTLFD------SRHLLYQLLWNMFSKEVEL-ADSMQTLFRGNSLASK-IMTFCFKVYG 1293
V+ TL++ +LL +L +E++ D +Q + GN K +++F G
Sbjct: 918 VIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARG 977
Query: 1294 ATYLQKLLDPLLRIVITSSD-------------WQH---------------VSFEVDPTR 1325
L++LL P+++ +I W + V+ E T
Sbjct: 978 QNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTY 1037
Query: 1326 LEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEK 1385
E LE + NL ++T+K ++IISS P LR + L
Sbjct: 1038 PEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVL----------------- 1080
Query: 1386 KENKKSVVSQRFPQNS----IGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRI----ER 1437
K+ + ++FP + + VG+ ++ R++NPAIV+P I+D +I R
Sbjct: 1081 ----KNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRR 1136
Query: 1438 GLKLMSKILQSIANHVLFTKE-EHMRPFNDFVKSNFDAARRFFLDIASDCPTSD------ 1490
L ++K+LQ A++ LF E EH+ N+++ + R++F + A + P +
Sbjct: 1137 NLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKE-ACNVPEPEEKFNMD 1195
Query: 1491 ------AVNHSLSFISDGNVLALHRLLWNNQEKI 1518
V+ + +IS +++ H LL +Q+ I
Sbjct: 1196 KYTDLVTVSKPVIYISIEEIISTHSLLLEHQDAI 1229
>gi|4506787 IQ motif containing GTPase activating protein 1 [Homo
sapiens]
Length = 1657
Score = 65.9 bits (159), Expect = 6e-10
Identities = 74/334 (22%), Positives = 141/334 (42%), Gaps = 79/334 (23%)
Query: 1242 VLVTLFD------SRHLLYQLLWNMFSKEVEL-ADSMQTLFRGNSLASK-IMTFCFKVYG 1293
V+ TL++ +LL +L +E++ D +Q + GN K +++F G
Sbjct: 1005 VIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARG 1064
Query: 1294 ATYLQKLLDPLLRIVITSSDWQHVSFEVD-------------------PTRLEPSESLEE 1334
L+++L P+++ ++ + VD P + P ++L
Sbjct: 1065 QNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAH 1124
Query: 1335 NQ---------RNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEK 1385
+ RN+ +T+KF AI+SS + P +R + L
Sbjct: 1125 EEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVL----------------- 1167
Query: 1386 KENKKSVVSQRFP----QNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRI----ER 1437
K + ++FP + +G+ ++ R++NPAIV+P I+D ++ R
Sbjct: 1168 ----KDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRR 1223
Query: 1438 GLKLMSKILQSIANHVLFTKEE-HMRPFNDFVKSNFDAARRFFLDIASDCPT-------- 1488
L ++K+LQ A++ +F + H+ N+++ ++ RRFF A D P
Sbjct: 1224 NLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFF-QTACDVPELQDKFNVD 1282
Query: 1489 --SDAV--NHSLSFISDGNVLALHRLLWNNQEKI 1518
SD V + +IS G ++ H LL ++Q+ I
Sbjct: 1283 EYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAI 1316
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 59.3 bits (142), Expect = 5e-08
Identities = 75/317 (23%), Positives = 131/317 (41%), Gaps = 69/317 (21%)
Query: 1251 HLLYQLLWNMFSKEVEL-ADSMQTLFRGN-SLASKIMTFCFKVYGATYLQKLLDPLLRIV 1308
+LL QL +E++ + Q + GN ++ ++ F G + LQ++L +++ V
Sbjct: 1004 YLLLQLFKTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDV 1063
Query: 1309 ITSS-------------DW-----------QHVSFEVDPTRL----EPSESLEENQRNLL 1340
+ +W H+ ++V P + E L+ RNLL
Sbjct: 1064 LEDKVLSVHTDPVHLYKNWINQTEAQTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLL 1123
Query: 1341 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQN 1400
MT+KF AI SS + P +R V L KAT+ EK +
Sbjct: 1124 AMTDKFLLAITSSVDQIPYGMRYVAKVL----------KATLAEKFPDATD-------SE 1166
Query: 1401 SIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRI----ERGLKLMSKILQSIANHVLFT 1456
VG+ ++ RF+NPA+V+P I+ + L ++++LQ A F+
Sbjct: 1167 VYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFS 1226
Query: 1457 -KEEHMRPFNDFVKSNF--------------DAARRFFLDIASDCPTSDAVNHSLSFISD 1501
+ +H+R ND+++ + RF +D SD AV + +I+
Sbjct: 1227 GQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPEERFAVDEYSDMV---AVAKPMVYITV 1283
Query: 1502 GNVLALHRLLWNNQEKI 1518
G ++ HRLL +Q+ I
Sbjct: 1284 GELVNTHRLLLEHQDCI 1300
>gi|207450721 ganglioside induced differentiation associated protein 2
isoform b [Homo sapiens]
Length = 496
Score = 40.4 bits (93), Expect = 0.025
Identities = 39/159 (24%), Positives = 62/159 (38%), Gaps = 5/159 (3%)
Query: 1582 EEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEI 1641
E+ + +L YQ G G + V R I+ D + + + + K Y +
Sbjct: 329 EDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVL 388
Query: 1642 VVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERL-LTGL 1700
V T T N +DFL K + V N+ AVY + + T + ++GL
Sbjct: 389 VYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGL 448
Query: 1701 KGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKV 1739
K ++ +D +L I EQ P LE D +V
Sbjct: 449 K--DKIHHVDSLHQLFSAISPEQIDFP--PFVLEYDARV 483
>gi|8923143 ganglioside induced differentiation associated protein 2
isoform a [Homo sapiens]
Length = 497
Score = 39.3 bits (90), Expect = 0.056
Identities = 36/151 (23%), Positives = 58/151 (38%), Gaps = 3/151 (1%)
Query: 1582 EEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEI 1641
E+ + +L YQ G G + V R I+ D + + + + K Y +
Sbjct: 329 EDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVL 388
Query: 1642 VVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERL-LTGL 1700
V T T N +DFL K + V N+ AVY + + T + ++GL
Sbjct: 389 VYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGL 448
Query: 1701 KGSKRLVFIDCPGKLAEHIEHEQQKLPAATL 1731
K ++ +D +L I EQ P L
Sbjct: 449 K--DKIHHVDSLHQLFSAISPEQIDFPPFVL 477
>gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo
sapiens]
Length = 1487
Score = 37.7 bits (86), Expect = 0.16
Identities = 62/279 (22%), Positives = 111/279 (39%), Gaps = 68/279 (24%)
Query: 1253 LYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLL-------DPLL 1305
L Q+L + E++ +D+ + L R + A I+ FK++ L +P++
Sbjct: 149 LLQVLRYLIEFELKESDNPRRLLRRGTCAFSIL---FKLFSEGLFSAKLFLTATLHEPIM 205
Query: 1306 RIVITSSDWQHVSFEVDPTRL----EPS-------------------ESLEENQRNLLQM 1342
++++ D E DP +L PS E +E N+ L+ +
Sbjct: 206 QLLVEDED----HLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVAL 261
Query: 1343 TEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSI 1402
KF + ++ FP LR + +Y+ S +++ V E +
Sbjct: 262 VNKFIGYLKQNTYCFPHSLRWIVSQMYKTL--SCVDRLEVGE-----------------V 302
Query: 1403 GAVGSAMFLR-FINPAIVSPYEAGILDKKPPPRIER-GLKLMSKILQSIANHVLFTKEEH 1460
A+ + + L FI PA+V+P + GI+ P + R L + ++LQ +A T E
Sbjct: 303 RAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLA----MTGSEE 358
Query: 1461 MRPFNDFVKSNFD-AARRFFLDI-----ASDCPTSDAVN 1493
P FD + FLD+ A + P +VN
Sbjct: 359 GDPRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVN 397
>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
[Homo sapiens]
Length = 5058
Score = 33.9 bits (76), Expect = 2.4
Identities = 62/285 (21%), Positives = 109/285 (38%), Gaps = 34/285 (11%)
Query: 2121 STHGLVINIIHSLCT-CSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFR 2179
ST G + +IH+ T QL +E R+SL ++ + +F+ + + +I+
Sbjct: 1049 STEGQELEVIHTTLTGLKQLLIIDED---FRISLFQY-MSQFFNSSVEDLLDNKCLISDN 1104
Query: 2180 SSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTE----LAQR 2235
++S F L + + A + + M T WL WTE ++Q
Sbjct: 1105 KHISSVNYSTSEESSFVFPLAQIFSNLSANVSVFNKFMSIHCTVSWLQMWTEIWETISQL 1164
Query: 2236 FAFQYNPSLQPRALVVFGCISKRVSHG--QIKQIIRILSKALESCLKGPDTYNSQVLIEA 2293
F F N + + HG Q+ + K +SC T+N LI
Sbjct: 1165 FKFDMN-------------VFTSLHHGFTQLLDELEDDVKVSKSCQGILPTHNVARLILN 1211
Query: 2294 TVIALTKLQPLLNKDSPLHKALFWVAV--AVLQLDEVNLYSAGTAL--LEQNLHTLDSLR 2349
+T+ N + L F VA+ A++ + ++NL +L +E LH L +
Sbjct: 1212 LFKNVTQANDFHNWEDFLDLRDFLVALGNALVSVKKLNLEQVEKSLFTMEAALHQLKTFP 1271
Query: 2350 IFNDKSPE------EVFMAIRNPLEWHCKQMDHFVGLNFNSNFNF 2388
S E EVF+ + E+ + +D N+ N+
Sbjct: 1272 FNESTSREFLNSLLEVFIEFSSTSEYIVRNLDSINDFLSNNLTNY 1316
>gi|117606355 furry homolog [Homo sapiens]
Length = 3013
Score = 33.5 bits (75), Expect = 3.1
Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 7/111 (6%)
Query: 1853 TLLNIALLNLGSSDPSLRSAAYNLLCALTC---TFNLKIE----GQLLETSGLCIPANNT 1905
TLLN+ L ++ + + L+ L ++ K+ G +L + +P +
Sbjct: 1257 TLLNLVLFKASDTNREIYEISMQLMQILEAKLFVYSKKVAEQRPGSILYGTHGPLPPLYS 1316
Query: 1906 LFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNL 1956
+ + +S LA P LTL E F + + + L Y+ PWL N+
Sbjct: 1317 VSLALLSCELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNI 1367
>gi|119874201 furry-like [Homo sapiens]
Length = 3013
Score = 33.1 bits (74), Expect = 4.0
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 1854 LLNIALLNLGSSDPSLRSAAYNLLCALTCT-FNLKIEGQLLETSGLC-----IPANNTLF 1907
LLN+ L S S+ A LL L F + ++ T G+ +P ++
Sbjct: 1208 LLNLILFKAADSSRSIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLSQLSPLPHLYSVS 1267
Query: 1908 IVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNL 1956
+S+ LA P LTL E + + + L Y+ PW++N+
Sbjct: 1268 YYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQVMLHYLLPWMNNI 1316
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 33.1 bits (74), Expect = 4.0
Identities = 15/47 (31%), Positives = 22/47 (46%)
Query: 635 PSSGNTSQMSMDHEELLRTPGASLRKGKGNSSMDSAAGCSGTPPICR 681
PS S S+ H +++ PG +S SAA G+P +CR
Sbjct: 1202 PSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCR 1248
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,820,802
Number of Sequences: 37866
Number of extensions: 4311326
Number of successful extensions: 10827
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 10701
Number of HSP's gapped (non-prelim): 106
length of query: 2839
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2719
effective length of database: 13,703,598
effective search space: 37260082962
effective search space used: 37260082962
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.