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Search of human proteins with 149999376
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149999376 MORN repeat containing 4 [Homo sapiens]
(146 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149999376 MORN repeat containing 4 [Homo sapiens] 305 1e-83
gi|30520314 MORN repeat containing 4 [Homo sapiens] 305 1e-83
gi|13376267 MORN repeat containing 1 [Homo sapiens] 70 6e-13
gi|18254456 testis-specific gene A2 [Homo sapiens] 66 9e-12
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens] 64 5e-11
gi|21704283 junctophilin 3 [Homo sapiens] 64 5e-11
gi|157502187 radial spoke head 10 homolog B [Homo sapiens] 64 5e-11
gi|18139549 SET domain-containing protein 7 [Homo sapiens] 63 1e-10
gi|21735575 junctophilin 1 [Homo sapiens] 62 1e-10
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] 62 1e-10
gi|50355990 MORN repeat containing 3 [Homo sapiens] 62 2e-10
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 61 3e-10
gi|40316935 alsin isoform 1 [Homo sapiens] 61 4e-10
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens] 57 4e-09
gi|225690502 junctophilin 4 [Homo sapiens] 56 9e-09
gi|225690500 junctophilin 4 [Homo sapiens] 56 9e-09
gi|224282170 MORN repeat containing 2 [Homo sapiens] 52 2e-07
gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ... 50 5e-07
gi|223278407 MORN repeat containing 5 [Homo sapiens] 44 5e-05
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ... 41 4e-04
gi|195972866 keratin 10 [Homo sapiens] 32 0.15
gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 30 0.73
gi|109148552 keratin 3 [Homo sapiens] 28 2.1
>gi|149999376 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 305 bits (780), Expect = 1e-83
Identities = 146/146 (100%), Positives = 146/146 (100%)
Query: 1 MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGS
Sbjct: 1 MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
Query: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK
Sbjct: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
Query: 121 LLRREKCSAIVQRAQSASKSARNLTA 146
LLRREKCSAIVQRAQSASKSARNLTA
Sbjct: 121 LLRREKCSAIVQRAQSASKSARNLTA 146
>gi|30520314 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 305 bits (780), Expect = 1e-83
Identities = 146/146 (100%), Positives = 146/146 (100%)
Query: 1 MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGS
Sbjct: 1 MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
Query: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK
Sbjct: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
Query: 121 LLRREKCSAIVQRAQSASKSARNLTA 146
LLRREKCSAIVQRAQSASKSARNLTA
Sbjct: 121 LLRREKCSAIVQRAQSASKSARNLTA 146
>gi|13376267 MORN repeat containing 1 [Homo sapiens]
Length = 497
Score = 70.1 bits (170), Expect = 6e-13
Identities = 43/117 (36%), Positives = 59/117 (50%), Gaps = 6/117 (5%)
Query: 6 GSFTY-SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFS-DGSRYE 63
G + Y +S Y GEWK GR+HG G+L+F DG Y G F +G G G ++ G +
Sbjct: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
Query: 64 GEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
G+F G+ G GV +EGE +G +G G L DG +G F +NK
Sbjct: 88 GQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQ----VYQGSFHDNK 140
Score = 60.5 bits (145), Expect = 5e-10
Identities = 30/95 (31%), Positives = 48/95 (50%)
Query: 12 SGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKF 71
SG+ + G++ G G+G + + GG Y G +G+ G G L DG Y+G F K
Sbjct: 82 SGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
Query: 72 NGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106
+G G + + ++G++ R G G+L DGS
Sbjct: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGS 176
Score = 60.1 bits (144), Expect = 7e-10
Identities = 31/100 (31%), Positives = 49/100 (49%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
G Y +G Y GE G R G G L+ DG Y G F + +G G + F +G +Y+G+
Sbjct: 99 GVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
Query: 66 FAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDG 105
+ + + G GV D T++G++ + G G + G
Sbjct: 159 WVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSG 198
Score = 60.1 bits (144), Expect = 7e-10
Identities = 28/80 (35%), Positives = 46/80 (57%)
Query: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFN 72
G+ Y+G + + +RHG GQ++F +G Y G + G GVL +DGS Y+G++ F+
Sbjct: 129 GQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFS 188
Query: 73 GVGVFIRYDNMTFEGEFKNG 92
G+G +T+ G + NG
Sbjct: 189 GLGSMAHCSGVTYYGLWING 208
Score = 53.5 bits (127), Expect = 6e-08
Identities = 23/64 (35%), Positives = 34/64 (53%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
G + +G++Y G+W RR G G L ADG TY G + + +F+G G + G Y G
Sbjct: 145 GQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGL 204
Query: 66 FAQG 69
+ G
Sbjct: 205 WING 208
>gi|18254456 testis-specific gene A2 [Homo sapiens]
Length = 309
Score = 66.2 bits (160), Expect = 9e-12
Identities = 34/87 (39%), Positives = 48/87 (55%)
Query: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFN 72
GE G + G RHG G+ +G TY G +E G +G G+ F +G+RY GE+ + K +
Sbjct: 18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKH 77
Query: 73 GVGVFIRYDNMTFEGEFKNGRVDGFGL 99
G G FI D +EGE+ N G G+
Sbjct: 78 GQGTFIYPDGSRYEGEWANDLRHGHGV 104
Score = 66.2 bits (160), Expect = 9e-12
Identities = 31/85 (36%), Positives = 48/85 (56%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
+G +G+ Y G ++ G+RHG G F +G Y+G + +G G + DGSRYEG
Sbjct: 33 RGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEG 92
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEF 89
E+A +G GV+ +N T+ GE+
Sbjct: 93 EWANDLRHGHGVYYYINNDTYTGEW 117
Score = 54.7 bits (130), Expect = 3e-08
Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
+G + + +G Y GE+ ++HG G ++ DG Y G + N L +G GV + + Y G
Sbjct: 56 QGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
Query: 65 EFAQGKFNGVGVFIRYD-NMTFEGEFKNGRVDG 96
E+ + +G G ++ + + G + NG+ +G
Sbjct: 116 EWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148
>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
Length = 870
Score = 63.9 bits (154), Expect = 5e-11
Identities = 34/86 (39%), Positives = 44/86 (51%)
Query: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNG 73
E Y GE G G G F G TY G F GL +G G ++DG +YEG+F +
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
Query: 74 VGVFIRYDNMTFEGEFKNGRVDGFGL 99
GV+ D +EGE NG +GFG+
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGM 169
Score = 63.9 bits (154), Expect = 5e-11
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 15/123 (12%)
Query: 10 YSSGEEYRGEWKEGRRHGFGQLMF-ADGGTYLGHFENGLFNGFGVLT----------FSD 58
Y SG Y G+W++ RHG G++ + Y G +E G+ NGFG T +
Sbjct: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPL 280
Query: 59 GSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFEN 118
+ Y GEF G +G G F ++GE+ + + G G LTF +G EG F N
Sbjct: 281 RNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR----VYEGAFSN 336
Query: 119 NKL 121
+ +
Sbjct: 337 DHI 339
Score = 63.2 bits (152), Expect = 8e-11
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
+G + G YRG + EG HG G ++ADG Y G F + GV T+ DGS YEG
Sbjct: 98 EGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEG 157
Query: 65 EFAQGKFNGVGVF-IRYDNMTFEGEFKNGRVDGFGLLTF 102
E G NG G+F +++ G + NG+ G G + +
Sbjct: 158 EVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYY 196
Score = 58.2 bits (139), Expect = 2e-09
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
Query: 11 SSGEEYRGEWKEGRRHGFG----------QLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
++ EEY G W+ G ++GFG + Y+G F NG +G G ++ G+
Sbjct: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305
Query: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
Y+GE+ K +G+G + +EG F N + GF
Sbjct: 306 MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Score = 52.8 bits (125), Expect = 1e-07
Identities = 25/69 (36%), Positives = 36/69 (52%)
Query: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
+Y G GL+ G G F G Y G F++G +G G +I D + +EG+F
Sbjct: 85 SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144
Query: 98 GLLTFPDGS 106
G+ T+PDGS
Sbjct: 145 GVYTWPDGS 153
Score = 50.1 bits (118), Expect = 7e-07
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 7 SFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66
S Y EY GE+ G RHG G+ +A G Y G + + +G G LTF +G YEG F
Sbjct: 275 SSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAF 334
Query: 67 AQGKFNG 73
+ G
Sbjct: 335 SNDHIAG 341
Score = 49.3 bits (116), Expect = 1e-06
Identities = 21/47 (44%), Positives = 27/47 (57%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGF 51
+G F Y+SG Y GEW ++HG G+L F +G Y G F N GF
Sbjct: 296 RGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Score = 46.6 bits (109), Expect = 8e-06
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFA-DGGTYLGHFENGLFNGFGVLTFSDGSR 61
+ G +T+ G Y GE G R+GFG + +Y+GH+ NG +G G + ++
Sbjct: 142 MNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGT 201
Query: 62 --YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFG 98
YEG++ Q G G+ +EG++++ G G
Sbjct: 202 CWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
>gi|21704283 junctophilin 3 [Homo sapiens]
Length = 748
Score = 63.9 bits (154), Expect = 5e-11
Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 25/124 (20%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSRYEG 64
G F + G Y G W++G+ HG G G G Y G + +G F GV T+ G+ Y+G
Sbjct: 5 GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHG-FEVLGVYTWPSGNTYQG 63
Query: 65 EFAQGKFNGVGVFI----------------RY-------DNMTFEGEFKNGRVDGFGLLT 101
+AQGK +G+G+ RY + +EG + NG DG+G T
Sbjct: 64 TWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTET 123
Query: 102 FPDG 105
+ DG
Sbjct: 124 YSDG 127
Score = 60.1 bits (144), Expect = 7e-10
Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFS-DGSRYEG 64
G +T+ SG Y+G W +G+RHG G L Y G + +G +GV + +G++YEG
Sbjct: 51 GVYTWPSGNTYQGTWAQGKRHGIG-LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEG 109
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
++ G +G G D T++G++ G G+G+
Sbjct: 110 TWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Score = 52.4 bits (124), Expect = 1e-07
Identities = 23/55 (41%), Positives = 34/55 (61%)
Query: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQ 68
E Y GEWK +R GFG +DG Y G + + +G+G +TF DG++ EG++ Q
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQ 340
Score = 50.8 bits (120), Expect = 4e-07
Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 14/93 (15%)
Query: 62 YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKL 121
Y GE+ K +G GV R D + +EGE+ + R G+G +TFPDG+ + EG ++ N L
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGT----KEEGKYKQNIL 343
Query: 122 ----------LRREKCSAIVQRAQSASKSARNL 144
LR K V RA A++ A +
Sbjct: 344 VGGKRKNLIPLRASKIREKVDRAVEAAERAATI 376
Score = 39.3 bits (90), Expect = 0.001
Identities = 16/40 (40%), Positives = 22/40 (55%)
Query: 11 SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNG 50
S G +Y GEW RRHG+G + F DG G ++ + G
Sbjct: 306 SDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
Length = 870
Score = 63.9 bits (154), Expect = 5e-11
Identities = 34/86 (39%), Positives = 44/86 (51%)
Query: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNG 73
E Y GE G G G F G TY G F GL +G G ++DG +YEG+F +
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
Query: 74 VGVFIRYDNMTFEGEFKNGRVDGFGL 99
GV+ D +EGE NG +GFG+
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGM 169
Score = 63.9 bits (154), Expect = 5e-11
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 15/123 (12%)
Query: 10 YSSGEEYRGEWKEGRRHGFGQLMF-ADGGTYLGHFENGLFNGFGVLT----------FSD 58
Y SG Y G+W++ RHG G++ + Y G +E G+ NGFG T +
Sbjct: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPL 280
Query: 59 GSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFEN 118
+ Y GEF G +G G F ++GE+ + + G G LTF +G EG F N
Sbjct: 281 RNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR----VYEGAFSN 336
Query: 119 NKL 121
+ +
Sbjct: 337 DHI 339
Score = 63.2 bits (152), Expect = 8e-11
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
+G + G YRG + EG HG G ++ADG Y G F + GV T+ DGS YEG
Sbjct: 98 EGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEG 157
Query: 65 EFAQGKFNGVGVF-IRYDNMTFEGEFKNGRVDGFGLLTF 102
E G NG G+F +++ G + NG+ G G + +
Sbjct: 158 EVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYY 196
Score = 58.2 bits (139), Expect = 2e-09
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
Query: 11 SSGEEYRGEWKEGRRHGFG----------QLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
++ EEY G W+ G ++GFG + Y+G F NG +G G ++ G+
Sbjct: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305
Query: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
Y+GE+ K +G+G + +EG F N + GF
Sbjct: 306 MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Score = 52.8 bits (125), Expect = 1e-07
Identities = 25/69 (36%), Positives = 36/69 (52%)
Query: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
+Y G GL+ G G F G Y G F++G +G G +I D + +EG+F
Sbjct: 85 SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144
Query: 98 GLLTFPDGS 106
G+ T+PDGS
Sbjct: 145 GVYTWPDGS 153
Score = 50.1 bits (118), Expect = 7e-07
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 7 SFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66
S Y EY GE+ G RHG G+ +A G Y G + + +G G LTF +G YEG F
Sbjct: 275 SSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAF 334
Query: 67 AQGKFNG 73
+ G
Sbjct: 335 SNDHIAG 341
Score = 49.3 bits (116), Expect = 1e-06
Identities = 21/47 (44%), Positives = 27/47 (57%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGF 51
+G F Y+SG Y GEW ++HG G+L F +G Y G F N GF
Sbjct: 296 RGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Score = 46.6 bits (109), Expect = 8e-06
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFA-DGGTYLGHFENGLFNGFGVLTFSDGSR 61
+ G +T+ G Y GE G R+GFG + +Y+GH+ NG +G G + ++
Sbjct: 142 MNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGT 201
Query: 62 --YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFG 98
YEG++ Q G G+ +EG++++ G G
Sbjct: 202 CWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
>gi|18139549 SET domain-containing protein 7 [Homo sapiens]
Length = 366
Score = 62.8 bits (151), Expect = 1e-10
Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 9 TYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQ 68
TYSS + + G + G ++G G+ F DG T G++ + G GV T+ DG +G +
Sbjct: 29 TYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVD 88
Query: 69 GKFNGVGVFIRYD---NMTFEGEFKNGRVDGFGLLTFPDG 105
G+ NG YD + F+G++K+ G + +PDG
Sbjct: 89 GELNGPAQ--EYDTDGRLIFKGQYKDNIRHGVCWIYYPDG 126
Score = 53.9 bits (128), Expect = 5e-08
Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 41 GHFEN-GLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
GH ++ GL +GF +T+S R+EG F G+ NG G F +D T EG + + + G G+
Sbjct: 14 GHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGV 73
Query: 100 LTFPDG 105
T+ DG
Sbjct: 74 YTYEDG 79
Score = 46.6 bits (109), Expect = 8e-06
Identities = 23/75 (30%), Positives = 37/75 (49%)
Query: 22 EGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYD 81
+G HGF + ++ + G+F +G NG G F DGS EG + G GV+ D
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
Query: 82 NMTFEGEFKNGRVDG 96
+G + +G ++G
Sbjct: 79 GGVLQGTYVDGELNG 93
Score = 30.0 bits (66), Expect = 0.73
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 8/63 (12%)
Query: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHF-ENGLFNGFGVL-------TFSDGSRYEGEFA 67
++G++K+ RHG + + DGG+ +G E+G G + T G +GE
Sbjct: 106 FKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMI 165
Query: 68 QGK 70
+GK
Sbjct: 166 EGK 168
>gi|21735575 junctophilin 1 [Homo sapiens]
Length = 661
Score = 62.4 bits (150), Expect = 1e-10
Identities = 41/127 (32%), Positives = 59/127 (46%), Gaps = 25/127 (19%)
Query: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSR 61
+T G F + G Y G W+EG+ HG G G G Y G + +G F G T+ G+
Sbjct: 1 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHG-FEVVGGYTWPSGNT 59
Query: 62 YEGEFAQGKFNGVGVFIRYDNM-----------------------TFEGEFKNGRVDGFG 98
Y+G +AQGK +G+GV + M +EG + NG DG+G
Sbjct: 60 YQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYG 119
Query: 99 LLTFPDG 105
+ T+ DG
Sbjct: 120 VETYGDG 126
Score = 58.5 bits (140), Expect = 2e-09
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVL-TFSDGSRYEG 64
G +T+ SG Y+G W +G+RHG G + Y G + +G +GV + +RYEG
Sbjct: 50 GGYTWPSGNTYQGYWAQGKRHGLG-VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEG 108
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
++ G +G GV D T++G++ G G+G+
Sbjct: 109 TWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Score = 52.4 bits (124), Expect = 1e-07
Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 41/119 (34%)
Query: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
TY+G ++N NGFGV S+G +YEGE+A K +G +
Sbjct: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHG-----------------------Y 316
Query: 98 GLLTFPDGSHGIPRNEGLFENNKLLR--------------REKCSAIVQRAQSASKSAR 142
G FPDGS + EG ++NN L+R REK ++ AQ A+ AR
Sbjct: 317 GCTVFPDGS----KEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMAR 371
Score = 50.1 bits (118), Expect = 7e-07
Identities = 22/53 (41%), Positives = 32/53 (60%)
Query: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66
E Y GEWK +R+GFG ++G Y G + N +G+G F DGS+ EG++
Sbjct: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Score = 40.4 bits (93), Expect = 5e-04
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 11 SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGL 47
S+G +Y GEW +RHG+G +F DG G ++N +
Sbjct: 299 SNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
Length = 953
Score = 62.4 bits (150), Expect = 1e-10
Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG----TYLGHFENGLFNGFGVLTFSD-GS 60
G YS+ E Y+G ++EG RHGFG L Y GH+E G +G+G+ D G
Sbjct: 422 GICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGE 481
Query: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106
RY G + G+ +G GV + + ++G F+ + G G+L D S
Sbjct: 482 RYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDS 527
Score = 58.5 bits (140), Expect = 2e-09
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSR-----YEGEFAQGK 70
Y GEW GR HG G L + DG ++G+F GL +GFG+ S Y+ + +G
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
Query: 71 FNGVGVFIRYDNMTFEGEFKNGRVDGFGLL 100
G G+ + ++G F+ G GFG+L
Sbjct: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVL 447
Score = 50.4 bits (119), Expect = 5e-07
Identities = 34/90 (37%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQG-KF 71
GE Y G W+ G+RHG G ++ G Y G F+ G G+L D S YEG F +
Sbjct: 480 GERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTL 539
Query: 72 NGVGVFIRYDNMTFEGEFKNGRVDGFGLLT 101
G G + T EG F +G G GL T
Sbjct: 540 MGKGKVTFPNGFTLEGSFGSGA--GRGLHT 567
Score = 45.4 bits (106), Expect = 2e-05
Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 11/113 (9%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG-----TYLGHFENGLFNGFGVLTFSDG 59
KG+ + G + G + +G HGFG + Y H+ G G+G+ +S
Sbjct: 370 KGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTD 429
Query: 60 SRYEGEFAQGKFNGVGVFIRYDN----MTFEGEFKNGRVDGFGLLTFPDGSHG 108
Y+G F +G +G GV + G ++ G+ G+G+ DG G
Sbjct: 430 EVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI--EEDGDRG 480
Score = 32.3 bits (72), Expect = 0.15
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 9/72 (12%)
Query: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFI-------RYDNMTFEGEFK 90
TY G + G +G G L + DG + G F QG +G G+ + ++D ++ ++
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFD--CYKCHWR 414
Query: 91 NGRVDGFGLLTF 102
G + G+G+ +
Sbjct: 415 EGSMCGYGICEY 426
Score = 32.0 bits (71), Expect = 0.19
Identities = 16/45 (35%), Positives = 21/45 (46%)
Query: 62 YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106
YEGE+ +G+ +G G D G F G GFG+ P S
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQAS 402
Score = 28.5 bits (62), Expect = 2.1
Identities = 12/26 (46%), Positives = 17/26 (65%)
Query: 84 TFEGEFKNGRVDGFGLLTFPDGSHGI 109
T+EGE+ GR G G L +PDG + +
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRNHV 382
>gi|50355990 MORN repeat containing 3 [Homo sapiens]
Length = 240
Score = 61.6 bits (148), Expect = 2e-10
Identities = 30/75 (40%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNG 73
E Y G+W +R G+G++ +++G Y G +EN NG G+L +G+RYEG + +G NG
Sbjct: 112 EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNG 171
Query: 74 VGVFIRYDN-MTFEG 87
G F D+ FEG
Sbjct: 172 AGRFFHLDHGQLFEG 186
Score = 56.2 bits (134), Expect = 9e-09
Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 13 GEEYRGEWKEGRRHGFGQLMFADGGT------YLGHFENGLFNGFGVLTFSDGSRYEGEF 66
G Y G+WK G+R G+G L D T Y G ++ +G+G+ F YEG++
Sbjct: 59 GAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDW 118
Query: 67 AQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFE 117
+ +G G + +EG+++N + +G G+L +G+ R EG +E
Sbjct: 119 CGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGN----RYEGCWE 165
Score = 48.5 bits (114), Expect = 2e-06
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVG 75
Y G WK ++ G+G F Y G + +G+G + +S+G YEG++ K NG G
Sbjct: 91 YSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEG 150
Query: 76 VFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKLLRREKCSAIV 131
+ + +EG ++ G +G G D HG LFE + KC ++
Sbjct: 151 MLRLKNGNRYEGCWERGMKNGAGRFFHLD--HG-----QLFEGFWVDNMAKCGTMI 199
Score = 46.6 bits (109), Expect = 8e-06
Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Query: 12 SGEEYRGEWKEGRRHGFG-QLMFADGGTYLGHFENGLFNGFGVLTFSDGSR------YEG 64
+G+ Y GEW++ +HG G Q+ G Y G ++ G +G+G L+ D Y G
Sbjct: 34 NGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSG 93
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
+ K +G G+ +EG++ + G+G + + +G EG +EN+K
Sbjct: 94 WWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGD----IYEGQWENDK 145
Score = 43.9 bits (102), Expect = 5e-05
Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSD-GSRYEG 64
G YS+G+ Y G+W+ + +G G L +G Y G +E G+ NG G D G +EG
Sbjct: 127 GRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEG 186
Score = 28.9 bits (63), Expect = 1.6
Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 8/49 (16%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGV 53
+G +G Y G W+ G ++G G+ D G LF GF V
Sbjct: 149 EGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQ--------LFEGFWV 189
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 61.2 bits (147), Expect = 3e-10
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVL-TFSDGSRYEG 64
G +T+ SG + G W +G+RHG G + Y G + +G +G+ + S G++YEG
Sbjct: 50 GVYTWPSGNTFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEG 108
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
+ G +G G D T++G+F NG G+G+
Sbjct: 109 TWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Score = 57.4 bits (137), Expect = 4e-09
Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 25/127 (19%)
Query: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSR 61
++ G F + G Y G W+ G+ HG G G G Y G + G F GV T+ G+
Sbjct: 1 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFG-FEVAGVYTWPSGNT 59
Query: 62 YEGEFAQGKFNGVGVFI----------------RY-------DNMTFEGEFKNGRVDGFG 98
+EG ++QGK +G+G+ RY +EG + NG DG+G
Sbjct: 60 FEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYG 119
Query: 99 LLTFPDG 105
T+ DG
Sbjct: 120 TETYADG 126
Score = 47.0 bits (110), Expect = 6e-06
Identities = 22/53 (41%), Positives = 30/53 (56%)
Query: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66
E Y GEWK +R GFG + G Y G + + L +G+G T DG R EG++
Sbjct: 289 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKY 341
Score = 43.1 bits (100), Expect = 8e-05
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 18/95 (18%)
Query: 62 YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKL 121
Y GE+ K +G GV R + +EGE+ + G+G T PDG R EG + +N L
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGH----REEGKYRHNVL 346
Query: 122 LR--------------REKCSAIVQRAQSASKSAR 142
++ R+K V+ AQ A+ AR
Sbjct: 347 VKDTKRRMLQLKSNKVRQKVEHSVEGAQRAAAIAR 381
Score = 33.1 bits (74), Expect = 0.086
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 11 SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGL 47
SSG Y GEW + RHG+G DG G + + +
Sbjct: 309 SSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNV 345
>gi|40316935 alsin isoform 1 [Homo sapiens]
Length = 1657
Score = 60.8 bits (146), Expect = 4e-10
Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 6/109 (5%)
Query: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFAD---GGTYLGHFENGLFNGFGVLTFSDG 59
L G T SS + G+W ++ G+G +F D G Y+G +++ + G GV+ G
Sbjct: 1138 LRSGKLTSSSPSMFIGQWVMDKKAGYG--VFDDITRGEKYMGMWQDDVCQGNGVVVTQFG 1195
Query: 60 SRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNG-RVDGFGLLTFPDGSH 107
YEG F K G GV + D+ +EGEF + + G G LT P+G +
Sbjct: 1196 LYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPNGDY 1244
Score = 58.9 bits (141), Expect = 1e-09
Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 5/90 (5%)
Query: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVL-----TFSDGSRYEGEFAQGK 70
Y G W G+ HG G L + DG Y G F NGL +G+G + Y G + +GK
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108
Query: 71 FNGVGVFIRYDNMTFEGEFKNGRVDGFGLL 100
G GV+ FEG F++ G GLL
Sbjct: 1109 MCGQGVYSYASGEVFEGCFQDNMRHGHGLL 1138
Score = 46.6 bits (109), Expect = 8e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 16/118 (13%)
Query: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGV-----LTFSDGSRYEGEFAQ 68
+ Y G WKEG+ G G +A G + G F++ + +G G+ LT S S + G++
Sbjct: 1098 DHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVM 1157
Query: 69 GKFNGVGVFIRYDNMT----FEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKLL 122
K G GVF D++T + G +++ G G++ G + EG F NK++
Sbjct: 1158 DKKAGYGVF---DDITRGEKYMGMWQDDVCQGNGVVVTQFGLY----YEGNFHLNKMM 1208
Score = 40.8 bits (94), Expect = 4e-04
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 14/115 (12%)
Query: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGT-----YLGHFENGLFNGFGVLTFSDG 59
+G + G+ Y G ++ G G+G+ + Y+GH++ G G GV +++ G
Sbjct: 1061 RGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVYSYASG 1120
Query: 60 SRYEGEFAQGKFNGVGVFIRYDNMT------FEGEFKNGRVDGFGLLTFPDGSHG 108
+EG F +G G+ +R +T F G++ + G+G+ F D + G
Sbjct: 1121 EVFEGCFQDNMRHGHGL-LRSGKLTSSSPSMFIGQWVMDKKAGYGV--FDDITRG 1172
Score = 39.7 bits (91), Expect = 0.001
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMT------FEGEFKN 91
TY G + +G +G GVL + DG Y G F G +G G + R N + G +K
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEY-RIPNKAMNKEDHYVGHWKE 1106
Query: 92 GRVDGFGLLTFPDGSHGIPRNEGLFENN 119
G++ G G+ ++ G EG F++N
Sbjct: 1107 GKMCGQGVYSYASGE----VFEGCFQDN 1130
Score = 27.3 bits (59), Expect = 4.7
Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 4/40 (10%)
Query: 79 RYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFEN 118
R + T++G + +G+ G G+L +PDG G+F N
Sbjct: 1043 RLKDATYDGRWLSGKPHGRGVLKWPDGK----MYSGMFRN 1078
>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
Length = 129
Score = 57.4 bits (137), Expect = 4e-09
Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 25/127 (19%)
Query: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSR 61
++ G F + G Y G W+ G+ HG G G G Y G + G F GV T+ G+
Sbjct: 1 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFG-FEVAGVYTWPSGNT 59
Query: 62 YEGEFAQGKFNGVGVFI----------------RY-------DNMTFEGEFKNGRVDGFG 98
+EG ++QGK +G+G+ RY +EG + NG DG+G
Sbjct: 60 FEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYG 119
Query: 99 LLTFPDG 105
T+ DG
Sbjct: 120 TETYADG 126
Score = 33.9 bits (76), Expect = 0.050
Identities = 13/27 (48%), Positives = 17/27 (62%)
Query: 11 SSGEEYRGEWKEGRRHGFGQLMFADGG 37
SSG +Y G W G + G+G +ADGG
Sbjct: 101 SSGAKYEGTWNNGLQDGYGTETYADGG 127
>gi|225690502 junctophilin 4 [Homo sapiens]
Length = 628
Score = 56.2 bits (134), Expect = 9e-09
Identities = 40/124 (32%), Positives = 53/124 (42%), Gaps = 26/124 (20%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSRYEG 64
G F + G Y G W+ GR HG+G G Y G + +G F GV T G Y+G
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHG-FESLGVFTGPGGHSYQG 63
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEF-----------------------KNGRVDGFGLLT 101
+ QGK G+GV R T+ GE+ K+G DG+G T
Sbjct: 64 HWQQGKREGLGVE-RKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
Query: 102 FPDG 105
+ DG
Sbjct: 123 YSDG 126
Score = 55.5 bits (132), Expect = 2e-08
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
G FT G Y+G W++G+R G G + TY G + GL GV G RY G
Sbjct: 51 GVFTGPGGHSYQGHWQQGKREGLG-VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGL 109
Query: 66 FAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
+ G +G G D T++G+++ G+ G+G+
Sbjct: 110 WKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
Score = 46.6 bits (109), Expect = 8e-06
Identities = 23/60 (38%), Positives = 34/60 (56%)
Query: 11 SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGK 70
S+ E Y GEW+ RR GFG ++G Y G + +G+G T DGSR EG++ + +
Sbjct: 277 SATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
Score = 45.4 bits (106), Expect = 2e-05
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 17/93 (18%)
Query: 62 YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKL 121
Y GE+ + +G GV R + + +EGE+ R G+G T PDGS R EG ++ N+L
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGS----REEGKYKRNRL 337
Query: 122 -------------LRREKCSAIVQRAQSASKSA 141
LRR K V RA ++ A
Sbjct: 338 VHGGRVRSLLPLALRRGKVKEKVDRAVEGARRA 370
>gi|225690500 junctophilin 4 [Homo sapiens]
Length = 628
Score = 56.2 bits (134), Expect = 9e-09
Identities = 40/124 (32%), Positives = 53/124 (42%), Gaps = 26/124 (20%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSRYEG 64
G F + G Y G W+ GR HG+G G Y G + +G F GV T G Y+G
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHG-FESLGVFTGPGGHSYQG 63
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEF-----------------------KNGRVDGFGLLT 101
+ QGK G+GV R T+ GE+ K+G DG+G T
Sbjct: 64 HWQQGKREGLGVE-RKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
Query: 102 FPDG 105
+ DG
Sbjct: 123 YSDG 126
Score = 55.5 bits (132), Expect = 2e-08
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
G FT G Y+G W++G+R G G + TY G + GL GV G RY G
Sbjct: 51 GVFTGPGGHSYQGHWQQGKREGLG-VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGL 109
Query: 66 FAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
+ G +G G D T++G+++ G+ G+G+
Sbjct: 110 WKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
Score = 46.6 bits (109), Expect = 8e-06
Identities = 23/60 (38%), Positives = 34/60 (56%)
Query: 11 SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGK 70
S+ E Y GEW+ RR GFG ++G Y G + +G+G T DGSR EG++ + +
Sbjct: 277 SATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
Score = 45.4 bits (106), Expect = 2e-05
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 17/93 (18%)
Query: 62 YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKL 121
Y GE+ + +G GV R + + +EGE+ R G+G T PDGS R EG ++ N+L
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGS----REEGKYKRNRL 337
Query: 122 -------------LRREKCSAIVQRAQSASKSA 141
LRR K V RA ++ A
Sbjct: 338 VHGGRVRSLLPLALRRGKVKEKVDRAVEGARRA 370
>gi|224282170 MORN repeat containing 2 [Homo sapiens]
Length = 79
Score = 52.0 bits (123), Expect = 2e-07
Identities = 21/64 (32%), Positives = 35/64 (54%)
Query: 26 HGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTF 85
+GFG+L G Y G F++ +F+G G TF +G++Y G F + + G G + + +
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEW 61
Query: 86 EGEF 89
G F
Sbjct: 62 SGNF 65
Score = 42.7 bits (99), Expect = 1e-04
Identities = 20/53 (37%), Positives = 28/53 (52%)
Query: 49 NGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLT 101
NGFG L G+ YEG+F F+G+G + + + G F RV+G G T
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYT 54
Score = 42.4 bits (98), Expect = 1e-04
Identities = 20/61 (32%), Positives = 27/61 (44%)
Query: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
G + SG Y G++K+ HG G F +G Y G+F G G T G + G
Sbjct: 5 GRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWSGN 64
Query: 66 F 66
F
Sbjct: 65 F 65
Score = 33.9 bits (76), Expect = 0.050
Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 72 NGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKL 121
NG G + +EG+FK+ G G TFP+G+ + G F N++
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGA----KYTGNFNENRV 47
>gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1
[Homo sapiens]
Length = 941
Score = 50.4 bits (119), Expect = 5e-07
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Query: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVG 75
Y+GE+ + G+G+ + G +Y G F +G G + DGS + G F G G
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61
Query: 76 VFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKLLR 123
+ F+G +K + G G+ T+PDGS + GL+ +L++
Sbjct: 62 TMYMKTRL-FQGLYKADQRFGPGVETYPDGSQDV----GLWFREQLIK 104
>gi|223278407 MORN repeat containing 5 [Homo sapiens]
Length = 161
Score = 43.9 bits (102), Expect = 5e-05
Identities = 19/58 (32%), Positives = 33/58 (56%)
Query: 12 SGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQG 69
+G +Y GE+ +GR G + + Y+G ++G+F+G G L F GS+Y+ + G
Sbjct: 4 TGSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWENG 61
Score = 40.8 bits (94), Expect = 4e-04
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 59 GSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFEN 118
GS+Y GE+ G+ G +I + GE K+G G G L FP GS + + ++EN
Sbjct: 5 GSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGS----QYDAIWEN 60
Query: 119 NKLLR 123
++
Sbjct: 61 GLAIK 65
Score = 40.8 bits (94), Expect = 4e-04
Identities = 23/48 (47%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYE 63
Y GE K+G HG G L F G Y +ENGL G TFSDG Y+
Sbjct: 31 YVGEMKDGMFHGEGTLYFPSGSQYDAIWENGLAIK-GTYTFSDGLHYD 77
Score = 34.3 bits (77), Expect = 0.039
Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 1/77 (1%)
Query: 36 GGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVD 95
G Y+G + +G G + Y GE G F+G G ++ ++NG
Sbjct: 5 GSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWENGLAI 64
Query: 96 GFGLLTFPDGSHGIPRN 112
G TF DG H +N
Sbjct: 65 K-GTYTFSDGLHYDEKN 80
>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
[Homo sapiens]
Length = 717
Score = 40.8 bits (94), Expect = 4e-04
Identities = 19/66 (28%), Positives = 33/66 (50%)
Query: 35 DGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRV 94
DG Y G F + G+G ++ G Y G+F + +G+G ++ D +F G F
Sbjct: 87 DGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHR 146
Query: 95 DGFGLL 100
+G+G +
Sbjct: 147 EGYGTM 152
Score = 40.8 bits (94), Expect = 4e-04
Identities = 18/54 (33%), Positives = 28/54 (51%)
Query: 1 MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVL 54
M L G F++ +GE Y G++ HG G M+ DG ++ G F G+G +
Sbjct: 99 MKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTM 152
Score = 38.9 bits (89), Expect = 0.002
Identities = 21/73 (28%), Positives = 33/73 (45%)
Query: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRY 62
L +G + G Y+GE+ + G+G+ + G +Y G F +G G + DGS +
Sbjct: 78 LVQGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSF 137
Query: 63 EGEFAQGKFNGVG 75
G F G G
Sbjct: 138 TGTFYLSHREGYG 150
Score = 37.4 bits (85), Expect = 0.005
Identities = 19/55 (34%), Positives = 25/55 (45%)
Query: 52 GVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106
GV + DG Y+GEF G G F ++ G+F G G +PDGS
Sbjct: 81 GVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGS 135
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 32.3 bits (72), Expect = 0.15
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 4/79 (5%)
Query: 23 GRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDN 82
G G+G L GG++ G + + F G +F GS G F G F G G +
Sbjct: 69 GSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGG----FGG 124
Query: 83 MTFEGEFKNGRVDGFGLLT 101
F G F G GLL+
Sbjct: 125 GGFGGGFGGGFGGDGGLLS 143
>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
Length = 518
Score = 30.0 bits (66), Expect = 0.73
Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 11/89 (12%)
Query: 13 GEEYRGEWKEGRRHGFGQLM--------FADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
G +++G W +G G G F GG + GH G + G G F S Y G
Sbjct: 376 GNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGG-YQGGGYGGFQTSSSYTG 434
Query: 65 EFAQGKFNGVGVFIRYDNMTFEGEFKNGR 93
QG G RY + G+ GR
Sbjct: 435 SGYQG--GGYQQDNRYQDGGHHGDRGGGR 461
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 28.5 bits (62), Expect = 2.1
Identities = 31/102 (30%), Positives = 36/102 (35%), Gaps = 12/102 (11%)
Query: 27 GFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF-AQGKFNGVGVFIRYDNMTF 85
G G+ A G Y G F +G GFG F G G F G F G G F
Sbjct: 81 GGGRSSCAFAGGYGGGFGSGYGGGFGG-GFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGG 139
Query: 86 EGEFKN----------GRVDGFGLLTFPDGSHGIPRNEGLFE 117
G F G GFG FP G + N+ L +
Sbjct: 140 PGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQ 181
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.140 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,577,020
Number of Sequences: 37866
Number of extensions: 253231
Number of successful extensions: 608
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 376
Number of HSP's gapped (non-prelim): 118
length of query: 146
length of database: 18,247,518
effective HSP length: 92
effective length of query: 54
effective length of database: 14,763,846
effective search space: 797247684
effective search space used: 797247684
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.