Search of human proteins with 149944410

Search of human proteins with 149944410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149944410 hypothetical protein LOC57587 [Homo sapiens]
         (532 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149944410 hypothetical protein LOC57587 [Homo sapiens]            1065   0.0  
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  54   3e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    53   6e-07
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    49   1e-05
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           48   2e-05
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           48   2e-05
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    48   3e-05
gi|70980531 GGA binding partner [Homo sapiens]                         47   4e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         47   6e-05
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ...    45   1e-04
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  45   2e-04
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              45   2e-04
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s...    44   4e-04
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    44   4e-04
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    44   4e-04
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa...    43   6e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    43   8e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    43   8e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    43   8e-04
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         42   0.001
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         42   0.002
gi|7661936 scaffold attachment factor B2 [Homo sapiens]                41   0.002
gi|46399200 testis-specific bromodomain protein [Homo sapiens]         41   0.003
gi|46399198 testis-specific bromodomain protein [Homo sapiens]         41   0.003
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap...    41   0.003
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap...    41   0.003
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    40   0.004
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    40   0.004
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...    40   0.004
gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]        40   0.005

>gi|149944410 hypothetical protein LOC57587 [Homo sapiens]
          Length = 532

 Score = 1065 bits (2754), Expect = 0.0
 Identities = 532/532 (100%), Positives = 532/532 (100%)

Query: 1   MDQFGDILEGEVDHSFFDSDFEEGKKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTT 60
           MDQFGDILEGEVDHSFFDSDFEEGKKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTT
Sbjct: 1   MDQFGDILEGEVDHSFFDSDFEEGKKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTT 60

Query: 61  ENYLTEKGNERNVKFPPEHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRI 120
           ENYLTEKGNERNVKFPPEHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRI
Sbjct: 61  ENYLTEKGNERNVKFPPEHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRI 120

Query: 121 PKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSS 180
           PKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSS
Sbjct: 121 PKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSS 180

Query: 181 SSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPK 240
           SSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPK
Sbjct: 181 SSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPK 240

Query: 241 CGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKN 300
           CGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKN
Sbjct: 241 CGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKN 300

Query: 301 NSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKG 360
           NSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKG
Sbjct: 301 NSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKG 360

Query: 361 PQKHHFDQPSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPK 420
           PQKHHFDQPSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPK
Sbjct: 361 PQKHHFDQPSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPK 420

Query: 421 LYHSALNRQKEQQRIERENLALLKRLEAVKPTVGMKRSEQLMDYHRNMGYLNSSPLSRRA 480
           LYHSALNRQKEQQRIERENLALLKRLEAVKPTVGMKRSEQLMDYHRNMGYLNSSPLSRRA
Sbjct: 421 LYHSALNRQKEQQRIERENLALLKRLEAVKPTVGMKRSEQLMDYHRNMGYLNSSPLSRRA 480

Query: 481 RSTLGQYSPLRASRTSSATSGLSCRSERSAVDPSSGHPRRRPKPPNVRTAWL 532
           RSTLGQYSPLRASRTSSATSGLSCRSERSAVDPSSGHPRRRPKPPNVRTAWL
Sbjct: 481 RSTLGQYSPLRASRTSSATSGLSCRSERSAVDPSSGHPRRRPKPPNVRTAWL 532


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 69/257 (26%), Positives = 100/257 (38%), Gaps = 30/257 (11%)

Query: 20   DFEEGKKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTTENYLTEKGNERNVKFPPEH 79
            D + GK+  T S   K  D P +R   DT+  + +              +  N  F P  
Sbjct: 989  DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSH-------------SSSNRPFTPP- 1034

Query: 80   PVENDVTQTVSSFSLPASSRSKKLCDVTTGL--KIHVSIPNRIPKIVKEGEDDYYTDGEE 137
                  T T  S S  ++ RS+    V T    KI + IP     + K      YT    
Sbjct: 1035 ------TSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGS 1088

Query: 138  SSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSS-SGSGTDCLDAGSDSH 196
             S  G K H  S S+  S++   S + K  K   SSSS LSSS  S  G+       +S 
Sbjct: 1089 VSSSGSKSH-HSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSS 1147

Query: 197  LSDSSPSSKSSKKH----VSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTV 252
             S   P S    KH     S  T + P+ K  S +  + ++P + +P     P  S+   
Sbjct: 1148 QSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKP-NISPSHSRPPGGSDKLA 1206

Query: 253  TDVSPL-STPDISPLQS 268
            + + P+  TP  S  +S
Sbjct: 1207 SPMKPVPGTPPSSKAKS 1223


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 65/331 (19%), Positives = 120/331 (36%), Gaps = 24/331 (7%)

Query: 2   DQFGDILEGEVDHSFFDSDFEEGKKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTTE 61
           D  G+   G  D+   DS   +    +++S     + D  +  D D+ + NS++   +++
Sbjct: 525 DSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD 584

Query: 62  NYLTEKGNERNVKFPPEHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIP 121
           +  ++               ++D + + +S     SS S    D +       S  ++  
Sbjct: 585 SDSSDSS-------------DSDSSDSSNSSDSSDSSDSSDSSDSSD------SSDSKSD 625

Query: 122 KIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSS 181
               E +        +SSD        +  +  S+N   S        SS SSSS  SS+
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 182 SGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKC 241
           S   +D  D+ + S  SDSS SS S     S        +   S   S+ +  SS +   
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSS-----DSSNSNSSDSDSSNSSDSSDSSNS 740

Query: 242 GHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNN 301
               + S+ + +  S  S+   +   S +   ++D        ++       D  D  N+
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800

Query: 302 SKYLKAAKKGKEKHEPDVSSKSSSVLDSSLD 332
           S    ++         D  S +SS   +S D
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 45/198 (22%), Positives = 77/198 (38%), Gaps = 1/198 (0%)

Query: 133  TDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAG 192
            +D   SSD        S  +  S+N   S        +S+SS S +SS S   +D  ++ 
Sbjct: 895  SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954

Query: 193  SDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTV 252
              S+ SDSS SS SS  + S  +  S          S+++  SS +       + S+ + 
Sbjct: 955  DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014

Query: 253  TDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGK 312
            +  S  S+       S +   ++D        ++       +  D  ++S    ++    
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074

Query: 313  EKHEPDVSSKSSSVLDSS 330
                 D SS+SS   DSS
Sbjct: 1075 SSDSSD-SSESSDSSDSS 1091



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 62/315 (19%), Positives = 109/315 (34%), Gaps = 6/315 (1%)

Query: 18   DSDFEEGKKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTTENYLTEKGNERNVKFPP 77
            DS         +NS     + D     D    + +SN+   +  +  ++  +  N     
Sbjct: 727  DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786

Query: 78   EHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIVKEGEDDYYTDGEE 137
            +    +D + + +S     SS S    D +     + S  +         +    +D  +
Sbjct: 787  DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD---SSDSSNSSDSSD 843

Query: 138  SSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDA--GSDS 195
            SSD        S +   S+N   S        SS SS S  S+ S + +D  D+   SDS
Sbjct: 844  SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903

Query: 196  HLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDV 255
              SDSS SS SS    S  +  S      S    +     S+         +S ++    
Sbjct: 904  DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963

Query: 256  SPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEKH 315
            +   + D +   S +   ++D        ++       +  D  ++S    ++      +
Sbjct: 964  NSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023

Query: 316  EPDVSSKSSSVLDSS 330
              D SS SS   DSS
Sbjct: 1024 SSD-SSNSSDSSDSS 1037



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 43/197 (21%), Positives = 71/197 (36%), Gaps = 10/197 (5%)

Query: 134  DGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGS 193
            +   SSD     +     +  S+N   S        SS SS+S  +S+S   ++  D+  
Sbjct: 887  ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946

Query: 194  DSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVT 253
             S  S+SS SS SS          S      S   S+++  SS +       + S+ + +
Sbjct: 947  SSDSSNSSDSSNSSD---------SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997

Query: 254  DVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKE 313
              S  S+       S +   ++D         +       D  D  ++S    ++     
Sbjct: 998  SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057

Query: 314  KHEPDVSSKSSSVLDSS 330
                D SS SS   DSS
Sbjct: 1058 SDSSD-SSDSSDSSDSS 1073



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 53/213 (24%), Positives = 79/213 (37%), Gaps = 19/213 (8%)

Query: 127 GEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGT 186
           G DD  ++ + +S         S  +K + N   S +      S S+S + +S S+G+G 
Sbjct: 473 GNDDANSESDNNSSSRGDASYNSDESKDNGNGSDS-KGAEDDDSDSTSDTNNSDSNGNGN 531

Query: 187 ------DCLDAG---SDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSST 237
                 D  D+G   SDS  SDSS SS SS    S            S   S+    SS 
Sbjct: 532 NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSS-------DSDSSDSNSSSDSDSSD 584

Query: 238 TPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVED 297
           +        +S D+        + D S   S +   ++D K    K E+ S +     + 
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSS--DSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642

Query: 298 LKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSS 330
             +NS          +      SS SS   DSS
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/400 (21%), Positives = 140/400 (35%), Gaps = 48/400 (12%)

Query: 37  NDDPKERIDKDTKNVNS--NTGMQTTENYLTEKGNERNVKFPPEHPVENDVTQTVSSFSL 94
           N + K+ +++ TK  N    T ++++      K ++ + +  PE      V++  S    
Sbjct: 141 NPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDK 200

Query: 95  PASSRSKKLCDVTTGLKIHV-SIPNRIPKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAK 153
             S  SKK    T    +H  + P +  K  K   D       E+S +     +  +S  
Sbjct: 201 KDSKNSKK----TNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDD 256

Query: 154 PSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSG 213
            S N    +R      S + S   +  +           SD+   DS  + K SKK    
Sbjct: 257 ESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKN 316

Query: 214 ITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGI 273
           +     K   K   +ST+ +        G   +E +DT  D   L               
Sbjct: 317 VKKDDKKKDVKKDTESTDAES-------GDSKDERKDTKKDKKKLKK------------- 356

Query: 274 ANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEK------------HEPDVSS 321
            +D+K   KK    +     D +D +N+S+ LK A K  +K             E ++ S
Sbjct: 357 -DDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELES 415

Query: 322 KSS------SVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGK 375
           K S         DS  D++   K   ++ D +   K   +  KK  +K   D       K
Sbjct: 416 KESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKK 475

Query: 376 NYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSA 415
           +     E        +  L K+     EK GSK  I + A
Sbjct: 476 DAKKNAESTEM--ESDLELKKDKKHSKEKKGSKKDIKKDA 513



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 47/209 (22%), Positives = 79/209 (37%), Gaps = 20/209 (9%)

Query: 18  DSDFEEGKKCETNSVFDKQN---DDPKERIDKDTKNVNSNTGMQTTENYLTEKGNER--- 71
           D++ E+ K  + +S   K+N   DD K+ + KDT++ ++ +G    E   T+K  ++   
Sbjct: 297 DAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKK 356

Query: 72  ------NVKFPPEHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIVK 125
                   K+P     E+   +   + S      SK         KI  S  +      K
Sbjct: 357 DDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESK 416

Query: 126 EGEDDYYTDGEESSDDGKKYHVKS------KSAKPSTNVKKSIRKKYCKVSSSSSSSLSS 179
           E + D   D ++S  D KK  VK+        ++P  + KK  +K   K    S      
Sbjct: 417 ESQKDEKKDKKDSKTDNKK-SVKNDEESTDADSEPKGDSKKG-KKDEKKGKKDSKKDDKK 474

Query: 180 SSSGSGTDCLDAGSDSHLSDSSPSSKSSK 208
             +    +  +  SD  L      SK  K
Sbjct: 475 KDAKKNAESTEMESDLELKKDKKHSKEKK 503



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 68/336 (20%), Positives = 117/336 (34%), Gaps = 61/336 (18%)

Query: 143 KKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSS---------------SLSSSSSGSGTD 187
           K  + KSK  K  T +KK  +KK    +++  S                    SS     
Sbjct: 112 KAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQ 171

Query: 188 CLDAGSDSHLSDSSPSSKSSKKHVS-------------GITLLSPKHKYKSGIKSTETQP 234
              + S S  +  S +SK+  K+ S                 L  K+  K  +K ++T  
Sbjct: 172 SKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSN 231

Query: 235 SSTTPKCGH----------YPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQ 284
              +  C              +  ++++   + L     +  +++ L      K   KK 
Sbjct: 232 DPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKN 291

Query: 285 ENVSQEI-YEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDT 343
              S +   ED +D K +SK +K   K K+  + DV   + S    S D + ++K     
Sbjct: 292 AKKSSDAESEDSKDAKKDSKKVKKNVK-KDDKKKDVKKDTESTDAESGDSKDERK----- 345

Query: 344 MDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAE 403
            D     K   + DKK   K + +      G           +  R + R LK+ S+  +
Sbjct: 346 -DTKKDKKKLKKDDKKKDTKKYPESTDTESGD---------AKDARNDSRNLKKASKNDD 395

Query: 404 KPGSKSTIPRSADHPPKLYHSALNRQKEQQRIEREN 439
           K      I  S D   +L        KE Q+ E+++
Sbjct: 396 KKKDAKKITFSTDSESEL------ESKESQKDEKKD 425


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 74/337 (21%), Positives = 115/337 (34%), Gaps = 57/337 (16%)

Query: 216  LLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTD-VSPLSTPDISPLQSFELGIA 274
            LLSPK     G K     P  T P  G      +    D V PL   D+  L S   GI 
Sbjct: 1695 LLSPKES-SGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIE 1753

Query: 275  N----------------------DQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGK 312
                                   ++  +   +E    EI+  V+D    SK  K   KG+
Sbjct: 1754 GPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGE 1813

Query: 313  EKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSVA 372
            ++ + D S +S S    S +H+ +++                   +    K H       
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRAR---------KRSSKSKSH------- 1857

Query: 373  PGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQ 432
                    R + R   R  +R     SR   + G +S         PK  H + +R++++
Sbjct: 1858 --------RSQTRSRSRSRRRRRSSRSRSKSR-GRRSVSKEKRKRSPK--HRSKSRERKR 1906

Query: 433  QR-IERENLALLKRLEAVKPTVGMKRSEQLMDYHRNMGYLNSSPLSRRARSTLGQYSPLR 491
            +R   R+N   ++             +       R++G   S  +S   RS     +P R
Sbjct: 1907 KRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSR----TPSR 1962

Query: 492  ASRTSSATSGLSCRSERSAVDPSSGHPRRRPKPPNVR 528
             SRT S  S    R  R+     S  P RR + P+ R
Sbjct: 1963 RSRTPSRRSRTPSRRSRTP-SRRSRTPSRRSRTPSRR 1998



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 36/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)

Query: 115  SIPNRIPKIVKEGEDDY-----YTDGEESS------DDGKKYHVKSKSAKPSTNVKKSIR 163
            S+P R  +   E +DDY       D  E S      D G+K   +  S +  +   KS  
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833

Query: 164  KKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITL------L 217
             K  K +S S S     SS S +      S S       SS+S  K     ++       
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 218  SPKHKYKS 225
            SPKH+ KS
Sbjct: 1894 SPKHRSKS 1901


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 74/337 (21%), Positives = 115/337 (34%), Gaps = 57/337 (16%)

Query: 216  LLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTD-VSPLSTPDISPLQSFELGIA 274
            LLSPK     G K     P  T P  G      +    D V PL   D+  L S   GI 
Sbjct: 1695 LLSPKES-SGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIE 1753

Query: 275  N----------------------DQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGK 312
                                   ++  +   +E    EI+  V+D    SK  K   KG+
Sbjct: 1754 GPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGE 1813

Query: 313  EKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSVA 372
            ++ + D S +S S    S +H+ +++                   +    K H       
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRAR---------KRSSKSKSH------- 1857

Query: 373  PGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQ 432
                    R + R   R  +R     SR   + G +S         PK  H + +R++++
Sbjct: 1858 --------RSQTRSRSRSRRRRRSSRSRSKSR-GRRSVSKEKRKRSPK--HRSKSRERKR 1906

Query: 433  QR-IERENLALLKRLEAVKPTVGMKRSEQLMDYHRNMGYLNSSPLSRRARSTLGQYSPLR 491
            +R   R+N   ++             +       R++G   S  +S   RS     +P R
Sbjct: 1907 KRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSR----TPSR 1962

Query: 492  ASRTSSATSGLSCRSERSAVDPSSGHPRRRPKPPNVR 528
             SRT S  S    R  R+     S  P RR + P+ R
Sbjct: 1963 RSRTPSRRSRTPSRRSRTP-SRRSRTPSRRSRTPSRR 1998



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 36/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)

Query: 115  SIPNRIPKIVKEGEDDY-----YTDGEESS------DDGKKYHVKSKSAKPSTNVKKSIR 163
            S+P R  +   E +DDY       D  E S      D G+K   +  S +  +   KS  
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833

Query: 164  KKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITL------L 217
             K  K +S S S     SS S +      S S       SS+S  K     ++       
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 218  SPKHKYKS 225
            SPKH+ KS
Sbjct: 1894 SPKHRSKS 1901


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 38/103 (36%), Positives = 47/103 (45%), Gaps = 2/103 (1%)

Query: 170 SSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKS 229
           SSSSSSS SSSSS S +    + S S  S SS SS SS    S    L  +HK K    S
Sbjct: 152 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDS 211

Query: 230 TETQPSSTTPKCGH--YPEESEDTVTDVSPLSTPDISPLQSFE 270
            E + +   P   H    +ES     +  PL    I P  +F+
Sbjct: 212 REHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFK 254



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 69/284 (24%), Positives = 99/284 (34%), Gaps = 62/284 (21%)

Query: 140 DDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSH--- 196
           D  +  H  S S+  S++   S        SSSSSSS SSSSS S +    + S  H   
Sbjct: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200

Query: 197 LSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKS--------------------TETQPSS 236
                  SK S++H S     S  H   S   S                     E +P S
Sbjct: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMS 260

Query: 237 TTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQE-IYEDV 295
             PK    P+ +  T+T       P   P       I++ +++  KK++  S E +++  
Sbjct: 261 KEPK----PDSNLLTITSGQDKKAPSKRP------PISDSEELSAKKRKKSSSEALFKSF 310

Query: 296 EDL----------KNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMD 345
                        K   K     K GK K E + S K  S L              D +D
Sbjct: 311 SSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPP----------FDDIVD 360

Query: 346 LNHLLKAFLQLDKKGPQKHHFDQPSVA---PGKNYSFTREEVRQ 386
            N        +++    K   +QPS A      + SFT  + RQ
Sbjct: 361 PND-----SDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQ 399


>gi|70980531 GGA binding partner [Homo sapiens]
          Length = 441

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 70/293 (23%), Positives = 121/293 (41%), Gaps = 40/293 (13%)

Query: 191 AGSDSHLSDSSPSSKSSKKHVSGITLLS-------PKHKYKSGIKSTETQPSSTTPKCGH 243
           A S  HLS SSP     + H S I  LS       P++ + +    ++T P +   +  H
Sbjct: 36  AVSGVHLSPSSPEIVLDRDHSSSIGCLSSDAIISSPENTHAANSIVSQTIPKAQIQQSTH 95

Query: 244 -------YP-----EESEDTVTDVSPLSTP--DISPLQSFELGIANDQKVKIKKQENVSQ 289
                  +P     E+S  T+  V     P  ++S +Q  +    +  ++K+K  E   Q
Sbjct: 96  THLDISLFPLGLTDEKSNGTIALVDDSEDPGANVSNIQLQQK--ISSLEIKLKVSEEEKQ 153

Query: 290 EIYEDVEDLKNNSKYLKAAKKG--KEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLN 347
            I +DVE L      L   +KG  KEK +  +S +        L  +HKQ+ L D     
Sbjct: 154 RIKQDVESLMEKHNVL---EKGFLKEKEQEAISFQDRY---KELQEKHKQE-LEDMRKAG 206

Query: 348 HLLKAFLQLDKKGPQKHHFDQPSVAPGKNYSFTREEVRQ-----IDRENQRLLKELSRQA 402
           H   + +  + K   +    Q   A  K Y    E+        ++ ++QRLL+ L  + 
Sbjct: 207 HEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEK 266

Query: 403 E--KPGSKSTIPRSADHPPKLYHSALNRQKEQQRIERENLALLKRLEAVKPTV 453
           E  K   K  + + +    ++    L  ++++ +    + A L++ EAVK  V
Sbjct: 267 ELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEK-EAVKDAV 318


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 16/147 (10%)

Query: 72   NVKFPPEHPVEND-VTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIVKEGEDD 130
            N K P +   E D   ++ SS S  + S S      ++G +              EGE++
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSET-------------EGEEE 2586

Query: 131  YYTDGEESSDDGKKY--HVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDC 188
               +G+     G +      S++A P+++   S        SSSSSSS SSSSS S +  
Sbjct: 2587 GDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646

Query: 189  LDAGSDSHLSDSSPSSKSSKKHVSGIT 215
              + S S  S SS SS SS    S  T
Sbjct: 2647 SSSSSSSSSSSSSSSSSSSSSSSSSTT 2673



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 39/139 (28%), Positives = 53/139 (38%), Gaps = 6/139 (4%)

Query: 149  SKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSK 208
            S S+  S++   S        SSSSSSS SSSSS S +    + S S  +    SS SS 
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682

Query: 209  KHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQS 268
               +      P  +     K+T+ Q     P   H P +     T       P   P Q 
Sbjct: 2683 DEAAPAPTAGPSAQAALPTKATK-QAGKARPS-AHSPGKK----TPAPQPQAPPPQPTQP 2736

Query: 269  FELGIANDQKVKIKKQENV 287
             +       K + KK+E V
Sbjct: 2737 LQPKAQAGAKSRPKKREGV 2755



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 4/107 (3%)

Query: 133  TDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAG 192
            +    SS         S S+  S++   S        SSSSSSS SSSSS S +      
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674

Query: 193  SDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTP 239
             DS  S    ++ +     S    L  K   ++G    + +PS+ +P
Sbjct: 2675 EDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAG----KARPSAHSP 2717



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 42/164 (25%), Positives = 58/164 (35%), Gaps = 35/164 (21%)

Query: 133  TDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSL--------SSSSSGS 184
            TDG+ + + G     +  S  P +  K    +   + S SSSSS         SSSSSGS
Sbjct: 2521 TDGDLAQEPGPGLTFED-SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579

Query: 185  GTDCLDAG--------------------------SDSHLSDSSPSSKSSKKHVSGITLLS 218
             T+  + G                          S S  S SS SS SS    S  +  S
Sbjct: 2580 ETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS 2639

Query: 219  PKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPD 262
                  S   S+ +  SS++         S  T  + S  S+ D
Sbjct: 2640 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 34/120 (28%), Positives = 42/120 (35%), Gaps = 24/120 (20%)

Query: 170  SSSSSSSLSSSSSGSGTDCLD------------------------AGSDSHLSDSSPSSK 205
            SSSSSSS SS S   G +  D                        A S S  S SS SS 
Sbjct: 2568 SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627

Query: 206  SSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISP 265
            SS    S  +  S      S   S+ +  SS++         S  T  D S  S  + +P
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687


>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
           sapiens]
          Length = 1045

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 65/268 (24%), Positives = 113/268 (42%), Gaps = 54/268 (20%)

Query: 144 KYHVKSKSAKPSTNVKKS-IRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSP 202
           ++ V+S S + +   K +   +KY       S SLSS+ S + +     G+D  + +  P
Sbjct: 738 EFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTAS----TGTD-RVRNEKP 792

Query: 203 SSKSSKK--HVSGIT-LLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLS 259
             K   K  H+ G   +  P  ++ S  K +  Q SS+    G+Y  ES DT +D     
Sbjct: 793 GGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLD-GNYKNES-DTFSDSR--- 847

Query: 260 TPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDV-------EDLKNNSKYLKAAKKGK 312
                         ++D++ K K+++  ++ +  ++       +  K++ K  K  KK  
Sbjct: 848 --------------SSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKH 893

Query: 313 EKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQ---KHHFDQP 369
           +KH  D +S+S  V+    D     +V  DT           + D  GPQ   ++ F  P
Sbjct: 894 KKHHGDNASRSPVVITIDSDSDKDSEVKEDT-----------ECDNSGPQDPLQNEFLAP 942

Query: 370 SVAPGKNYSFTREEVRQIDRENQRLLKE 397
           S+ P     F  ++V  I+ E   L KE
Sbjct: 943 SLEP-----FETKDVVTIEAEFGVLDKE 965


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 154 PSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSG 213
           P + VKK  +K++ K SSSSSSS S S S S +      SDS  +    S K  KKH   
Sbjct: 179 PKSKVKKEEKKRH-KSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKN 237

Query: 214 ITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTV 252
               S KHK +   +    + +S+  +  +   + + TV
Sbjct: 238 ----SRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTV 272


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 49/178 (27%), Positives = 72/178 (40%), Gaps = 19/178 (10%)

Query: 149 SKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSK 208
           ++S+      KK  +KK C+ SSSSSSS SSSSS    D           +     K  K
Sbjct: 84  NESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSED-----------EEKKQGKRRK 132

Query: 209 KHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQS 268
           K  +     S    ++S  +S E+       K     E+   +++     S PD  PL S
Sbjct: 133 KKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSS 192

Query: 269 FELGIAN-DQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSS 325
                ++ ++ V+ KK+        E+ E  K   K  K  KK  +KH      KS S
Sbjct: 193 ESSSESDYEEDVQAKKKRRC-----EEREQAKEKVK--KKKKKQHKKHSKKKKKKSGS 243


>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
           sapiens]
          Length = 908

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 72/327 (22%), Positives = 131/327 (40%), Gaps = 50/327 (15%)

Query: 116 IPNRIPKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSS 175
           +P   P+  +   + + + G     D  + H+K+    P   V +    +  K S SSSS
Sbjct: 616 LPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNT---PKVIVAQKPDVEQNKSSPSSSS 672

Query: 176 SLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPS 235
           S SSSS    +D     SDS  SDSS  S S +                S I S  +  +
Sbjct: 673 SASSSSESDSSD-----SDSDSSDSSSESSSEESD-------------SSSISSHSSASA 714

Query: 236 STTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDV 295
           +   K GH    S++    +    T              ND+K K ++QE+  QE   + 
Sbjct: 715 NDVRKKGHGKTRSKEVDKLIRNQQT--------------NDRKQKERRQEHGHQETRTER 760

Query: 296 EDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQ 355
           E  + + K+      G    +P   +K +S  D   +  +  +V +D     H+      
Sbjct: 761 E--RRSEKHRDQNSSGSNWRDP--ITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKH 816

Query: 356 LD---KKGPQKHHFDQPSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIP 412
            D   K+G +++ F +      + ++   ++     R+++   KE++R  +  GS+S   
Sbjct: 817 GDPKKKRGERRNSFSE-----NEKHTHRIKDSENFRRKDRSKSKEMNR--KHSGSRSDED 869

Query: 413 RSADHPPKLYHSALNRQKEQQRIEREN 439
           R  +   + +  + +R  EQ R  ++N
Sbjct: 870 RYQNGAERRWEKS-SRYSEQSRESKKN 895


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 45/185 (24%), Positives = 75/185 (40%), Gaps = 14/185 (7%)

Query: 136 EESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDS 195
           EE  ++  K  ++    K  +  + S +K+  K      S   SSSS S +D   + SDS
Sbjct: 52  EEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDS 111

Query: 196 HLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDV 255
              D     +  KK        +  HK      S     S  + K     ++  +   D+
Sbjct: 112 EDEDKKQGKRRKKKK-------NRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDI 164

Query: 256 SPLST-----PDISPLQSFELGIAN-DQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAK 309
             LS       +  PL S  L  +   ++V+ KK+++ S+E  +  E  K   K+ K +K
Sbjct: 165 KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKS-SEEREKATEKTKKKKKHKKHSK 223

Query: 310 KGKEK 314
           K K+K
Sbjct: 224 KKKKK 228


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 45/185 (24%), Positives = 75/185 (40%), Gaps = 14/185 (7%)

Query: 136 EESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDS 195
           EE  ++  K  ++    K  +  + S +K+  K      S   SSSS S +D   + SDS
Sbjct: 62  EEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDS 121

Query: 196 HLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDV 255
              D     +  KK        +  HK      S     S  + K     ++  +   D+
Sbjct: 122 EDEDKKQGKRRKKKK-------NRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDI 174

Query: 256 SPLST-----PDISPLQSFELGIAN-DQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAK 309
             LS       +  PL S  L  +   ++V+ KK+++ S+E  +  E  K   K+ K +K
Sbjct: 175 KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKS-SEEREKATEKTKKKKKHKKHSK 233

Query: 310 KGKEK 314
           K K+K
Sbjct: 234 KKKKK 238


>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
            sapiens]
          Length = 2881

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 42/136 (30%), Positives = 54/136 (39%), Gaps = 25/136 (18%)

Query: 143  KKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSS-------SSSGSGTDCLDAGSDS 195
            KK  V  + ++ S++      +  C   SSSSSS SS       SSS S + C  A S S
Sbjct: 2119 KKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSS 2178

Query: 196  HLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDV 255
              S SS SS SS                +S     E Q   +T     Y EES      V
Sbjct: 2179 SSSTSSSSSSSSSS------------SEESDSDEEEAQKRESTTHMKAYDEES------V 2220

Query: 256  SPLSTPDISPLQSFEL 271
            + LST       SF++
Sbjct: 2221 ASLSTTQDETQDSFQM 2236



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 6/117 (5%)

Query: 121  PKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSS 180
            P++ K G +       +S  D ++    S+S+  S++   S  +     SSSSS S +SS
Sbjct: 2121 PRVHKRGSES----SSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 2176

Query: 181  SSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKST--ETQPS 235
            SS S T    + S S   +S    + ++K  S   + +   +  + + +T  ETQ S
Sbjct: 2177 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLSTTQDETQDS 2233



 Score = 32.7 bits (73), Expect = 0.85
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 119  RIPKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLS 178
            R+ K   E   D  +D E SS   +     S S+   +    S        S+SSSSS S
Sbjct: 2122 RVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSS 2181

Query: 179  SSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHV 211
            +SSS S +      SDS   +     + S  H+
Sbjct: 2182 TSSSSSSSSSSSEESDS--DEEEAQKRESTTHM 2212


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 65/308 (21%), Positives = 109/308 (35%), Gaps = 35/308 (11%)

Query: 25  KKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTTENYLTEKGNERNVKFPPEHPVEND 84
           K  E++S  +  +DD +E    D K      G+         K   +  K PP+    +D
Sbjct: 122 KASESSSSEESSDDDDEE----DQKKQPVQKGV---------KPQAKAAKAPPKKAKSSD 168

Query: 85  VTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNR----IPKIV--KEGEDDYYTDGEES 138
                SS   P  ++  K+  VT  +K     P +     PKI   K       +    S
Sbjct: 169 SDSDSSSEDEPPKNQKPKITPVT--VKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSS 226

Query: 139 SDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLS 198
           SDD       S+  K +   KK++ KK     +   ++ + +   S ++  D+ SD    
Sbjct: 227 SDD-------SEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE--DSSSDEEEE 277

Query: 199 DSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPL 258
              P       + S     +P  K     KS  TQP     +     E SED+  +    
Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPK-----KSLGTQPPKKAVEKQQPVESSEDSSDESDSS 332

Query: 259 STPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEKHEPD 318
           S  +  P     +  A  +    KK    S +  +      + +    A       ++P 
Sbjct: 333 SEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPA 392

Query: 319 VSSKSSSV 326
           V++KS +V
Sbjct: 393 VTTKSPAV 400



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 60/248 (24%), Positives = 86/248 (34%), Gaps = 29/248 (11%)

Query: 106 VTTGLKIHVSIPNRIPKIVKEGEDDYYTDGEESSDDGKK-----YHVKSKSAKPSTNVKK 160
           V  G+K         PK  K  + D  +  E+     +K       VK+++  P    + 
Sbjct: 146 VQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARA 205

Query: 161 SIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPK 220
           + +    K +SSSSSS SSSSS          S+   + ++P     KK V        K
Sbjct: 206 APKIANGKAASSSSSSSSSSSSDD--------SEEEKAAATPKKTVPKKQVVA------K 251

Query: 221 HKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLST--PDISPLQSFELGIANDQK 278
              K+    T    SS         E+ +       P S+  P  +P     LG    +K
Sbjct: 252 APVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKK 311

Query: 279 VKIKKQENVSQEIYEDVEDLKNNSK--------YLKAAKKGKEKHEPDVSSKSSSVLDSS 330
              K+Q   S E   D  D  +  +          KA  K     +   SS  SS  DSS
Sbjct: 312 AVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSS 371

Query: 331 LDHRHKQK 338
            D     K
Sbjct: 372 EDDEAPSK 379



 Score = 32.7 bits (73), Expect = 0.85
 Identities = 59/268 (22%), Positives = 91/268 (33%), Gaps = 46/268 (17%)

Query: 76  PPEHPVENDV---TQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIVKEGEDDYY 132
           PP+  VE      +   SS    +SS  +K       +    + P    K  +   D   
Sbjct: 308 PPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDS-- 365

Query: 133 TDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSS--GSGTDCLD 190
           +D + S DD          +KP+   K S  K      S +    ++     G G   L 
Sbjct: 366 SDSDSSEDD-------EAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418

Query: 191 AGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESED 250
             +DS  S+   SS   +K    +    PK   K+ +     Q           P+ S D
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQA----------PQGSRD 468

Query: 251 TVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKK 310
           + +D    S+ +             ++K      +   Q++       K  S     AKK
Sbjct: 469 SSSDSDSSSSEE------------EEEKTSKSAVKKKPQKVAGGAAPSKPAS-----AKK 511

Query: 311 GKEKHEPDVSSKSSSVLDSSLDHRHKQK 338
           GK +     SS SSS  DSS +   K K
Sbjct: 512 GKAE-----SSNSSSSDDSSEEEEEKLK 534


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 91/444 (20%), Positives = 169/444 (38%), Gaps = 68/444 (15%)

Query: 13  DHSFFDSDFE-EGKKCETNSVFDKQNDDPKE------RIDKDTKNVNSNTGMQTTENYLT 65
           +H   D+ FE + +K E     +K++    E      ++D +  + N  T  Q T     
Sbjct: 393 EHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTG 452

Query: 66  EKGNERNVKFPPEH-PVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIV 124
            +  + + K  P++ P        +   S+P+S       ++ T +++  S+ +      
Sbjct: 453 GEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDH------ 506

Query: 125 KEGEDDYYTDGEESSDDGKKYHVKSKSAK---PSTNVKKSIRKKYCKVSSSSSSSLSSSS 181
            +G+    T+ E  S    K ++ SK  +    S    K  ++ Y K++  S S+    S
Sbjct: 507 -QGDGSSGTEQEVESSS-VKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSN----S 560

Query: 182 SGSGTDCLDAGSDSHLSDSSP-----------SSKSSKKHV--SGITLLSPKHKYKSG-- 226
              G DC +   D     S                S  +H+  + ++LL  +   +    
Sbjct: 561 PIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPR 620

Query: 227 IKSTETQ-PSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQE 285
           +K+T  + P+ T P   +  EE  +TV +   LS     P++  +   ++D  +   K  
Sbjct: 621 VKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSV----PVRKKDKRNSSDSAIDNPKPN 676

Query: 286 NVSQEIYEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMD 345
            + +    +  D  ++S  + A  K   +    +S  SSS  D +  H +  K L+D   
Sbjct: 677 KLPKSKQSETVDQNSDSDEMLAILKEVSR----MSHSSSSDTDINEIHTN-HKTLYD--- 728

Query: 346 LNHLLKAFLQLDKKGPQKH-------HFD------QPSVAPGKNYSFTREEVRQIDRENQ 392
               LK     D KG +K         FD        S    K    T+ E    D E +
Sbjct: 729 ----LKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELE 784

Query: 393 RLLKELSRQAEKPGSKSTIPRSAD 416
           + +K +S+      +K  IP + D
Sbjct: 785 KEIKSMSKIGAARTTKKRIPNTKD 808



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 102/500 (20%), Positives = 178/500 (35%), Gaps = 97/500 (19%)

Query: 78   EHPVENDVTQTVSSFSL------------------PASSRSKKLCDVTTGLKIHVSIPNR 119
            EH VEN+V+  +    L                  P +S S + C+ T   K  +S+P R
Sbjct: 599  EHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVR 658

Query: 120  IPKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSS---- 175
              K  K    D   D  + +   K    ++      ++   +I K+  ++S SSSS    
Sbjct: 659  --KKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDI 716

Query: 176  --------SLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGI 227
                    +L    + +G D  D G     S +S S   +KK  S  + +  K       
Sbjct: 717  NEIHTNHKTLYDLKTQAGKD--DKGKRKRKSSTSGSDFDTKKGKSAKSSIISK------- 767

Query: 228  KSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENV 287
            K  +TQ  S+     +Y  E E  +  +S             ++G A   K +I   ++ 
Sbjct: 768  KKRQTQSESS-----NYDSELEKEIKSMS-------------KIGAARTTKKRIPNTKD- 808

Query: 288  SQEIYEDVEDLKNNSKYL-----KAAKKGKEKHEPDVSSKSSSVLDSSLDHR-HKQKVLH 341
                ++  ED K++ K +     K  K  +E    D   K      SS +    K   + 
Sbjct: 809  ----FDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIM 864

Query: 342  DTMDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGKNYSFTREEVRQI--DRENQRLLKE-- 397
            +  D         +L KK       D      GK  SFT  EVR++   +E  + LK   
Sbjct: 865  ELRD---------RLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKT 915

Query: 398  -------LSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQQRIERENLALLKRLEAVK 450
                   LS  AEK   K     +++   K        +K+    +++ + + ++ E+  
Sbjct: 916  CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSS 975

Query: 451  P-TVGMKRSEQLMDYHRNM-----GYLNSSPLSRRAR-STLGQYSPLRASRTSSATSGLS 503
              T  +   E++  + + +     G  +    S++ R  T  +   L      S   G S
Sbjct: 976  DGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDS 1035

Query: 504  CRSERSAVDPSSGHPRRRPK 523
            C S       +  + R + +
Sbjct: 1036 CDSSEDKKSKNGAYGREKKR 1055



 Score = 37.0 bits (84), Expect = 0.045
 Identities = 83/420 (19%), Positives = 146/420 (34%), Gaps = 103/420 (24%)

Query: 133  TDGEESSDDGKKYHVKSKSAKPSTNVKK--------SIRKKYCKVSSSSSSSL---SSSS 181
            +D EESS+D KK   ++ S K +  VK+        S ++K   ++SSSSS +     +S
Sbjct: 1118 SDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNS 1177

Query: 182  SGSGTD--------------------CLDAGS-----------DSHLSDSSPSSKSSKKH 210
             G G+                     C  +G            D    D+ P ++ +KK 
Sbjct: 1178 IGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKM 1237

Query: 211  V------------SGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSP- 257
            +             G +   P+   K   K  E  P     K     E   D+     P 
Sbjct: 1238 LLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPR 1297

Query: 258  ---------LSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAA 308
                     L+  D    +  +      ++VK + +  VS E  ED  D + +    + +
Sbjct: 1298 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED-SDFQESGVSEEVS 1356

Query: 309  KKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQ 368
            +   E+     S+K + + ++   ++ K+K            +  +Q D     K + ++
Sbjct: 1357 ESEDEQRPRTRSAKKAELEENQRSYKQKKK----------RRRIKVQEDSSSENKSNSEE 1406

Query: 369  PSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNR 428
                        +EE  + + E +   ++ +  ++ PG      R      KL     N 
Sbjct: 1407 EEE--------EKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNA 1458

Query: 429  QKEQQ----RI-----ERENLALLKRLEAVKPT-----------VGMKRSEQLMDYHRNM 468
             KE++    RI     ERE L  +  +E   PT              +  E L+  HRNM
Sbjct: 1459 LKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNM 1518



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 44/182 (24%), Positives = 77/182 (42%), Gaps = 34/182 (18%)

Query: 34   DKQNDDPKERIDK----DTKNVNSNTGMQTTENYLTEKGNERNVKFPPEHPVENDVTQTV 89
            D  ++DP+ RI K    +    N ++    + +   E+G +R  K   E+P + +    V
Sbjct: 1223 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1282

Query: 90   SSFSLPASSRSKK-------------LCDVTTG------LKIHVSIPNRIPKIV--KEGE 128
            +S S   S  SKK             + D  +G       K H  +  R  + V  ++ E
Sbjct: 1283 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE 1342

Query: 129  D-DYYTDG--EESSDDGKKYHVKSKSAKPS------TNVKKSIRKKYCKVSSSSSSSLSS 179
            D D+   G  EE S+   +   +++SAK +       + K+  +++  KV   SSS   S
Sbjct: 1343 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1402

Query: 180  SS 181
            +S
Sbjct: 1403 NS 1404


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 91/444 (20%), Positives = 169/444 (38%), Gaps = 68/444 (15%)

Query: 13  DHSFFDSDFE-EGKKCETNSVFDKQNDDPKE------RIDKDTKNVNSNTGMQTTENYLT 65
           +H   D+ FE + +K E     +K++    E      ++D +  + N  T  Q T     
Sbjct: 431 EHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTG 490

Query: 66  EKGNERNVKFPPEH-PVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIV 124
            +  + + K  P++ P        +   S+P+S       ++ T +++  S+ +      
Sbjct: 491 GEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDH------ 544

Query: 125 KEGEDDYYTDGEESSDDGKKYHVKSKSAK---PSTNVKKSIRKKYCKVSSSSSSSLSSSS 181
            +G+    T+ E  S    K ++ SK  +    S    K  ++ Y K++  S S+    S
Sbjct: 545 -QGDGSSGTEQEVESSS-VKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSN----S 598

Query: 182 SGSGTDCLDAGSDSHLSDSSP-----------SSKSSKKHV--SGITLLSPKHKYKSG-- 226
              G DC +   D     S                S  +H+  + ++LL  +   +    
Sbjct: 599 PIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPR 658

Query: 227 IKSTETQ-PSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQE 285
           +K+T  + P+ T P   +  EE  +TV +   LS     P++  +   ++D  +   K  
Sbjct: 659 VKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSV----PVRKKDKRNSSDSAIDNPKPN 714

Query: 286 NVSQEIYEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMD 345
            + +    +  D  ++S  + A  K   +    +S  SSS  D +  H +  K L+D   
Sbjct: 715 KLPKSKQSETVDQNSDSDEMLAILKEVSR----MSHSSSSDTDINEIHTN-HKTLYD--- 766

Query: 346 LNHLLKAFLQLDKKGPQKH-------HFD------QPSVAPGKNYSFTREEVRQIDRENQ 392
               LK     D KG +K         FD        S    K    T+ E    D E +
Sbjct: 767 ----LKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELE 822

Query: 393 RLLKELSRQAEKPGSKSTIPRSAD 416
           + +K +S+      +K  IP + D
Sbjct: 823 KEIKSMSKIGAARTTKKRIPNTKD 846



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 102/500 (20%), Positives = 178/500 (35%), Gaps = 97/500 (19%)

Query: 78   EHPVENDVTQTVSSFSL------------------PASSRSKKLCDVTTGLKIHVSIPNR 119
            EH VEN+V+  +    L                  P +S S + C+ T   K  +S+P R
Sbjct: 637  EHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVR 696

Query: 120  IPKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSS---- 175
              K  K    D   D  + +   K    ++      ++   +I K+  ++S SSSS    
Sbjct: 697  --KKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDI 754

Query: 176  --------SLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGI 227
                    +L    + +G D  D G     S +S S   +KK  S  + +  K       
Sbjct: 755  NEIHTNHKTLYDLKTQAGKD--DKGKRKRKSSTSGSDFDTKKGKSAKSSIISK------- 805

Query: 228  KSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENV 287
            K  +TQ  S+     +Y  E E  +  +S             ++G A   K +I   ++ 
Sbjct: 806  KKRQTQSESS-----NYDSELEKEIKSMS-------------KIGAARTTKKRIPNTKD- 846

Query: 288  SQEIYEDVEDLKNNSKYL-----KAAKKGKEKHEPDVSSKSSSVLDSSLDHR-HKQKVLH 341
                ++  ED K++ K +     K  K  +E    D   K      SS +    K   + 
Sbjct: 847  ----FDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIM 902

Query: 342  DTMDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGKNYSFTREEVRQI--DRENQRLLKE-- 397
            +  D         +L KK       D      GK  SFT  EVR++   +E  + LK   
Sbjct: 903  ELRD---------RLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKT 953

Query: 398  -------LSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQQRIERENLALLKRLEAVK 450
                   LS  AEK   K     +++   K        +K+    +++ + + ++ E+  
Sbjct: 954  CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSS 1013

Query: 451  P-TVGMKRSEQLMDYHRNM-----GYLNSSPLSRRAR-STLGQYSPLRASRTSSATSGLS 503
              T  +   E++  + + +     G  +    S++ R  T  +   L      S   G S
Sbjct: 1014 DGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDS 1073

Query: 504  CRSERSAVDPSSGHPRRRPK 523
            C S       +  + R + +
Sbjct: 1074 CDSSEDKKSKNGAYGREKKR 1093



 Score = 37.0 bits (84), Expect = 0.045
 Identities = 83/420 (19%), Positives = 146/420 (34%), Gaps = 103/420 (24%)

Query: 133  TDGEESSDDGKKYHVKSKSAKPSTNVKK--------SIRKKYCKVSSSSSSSL---SSSS 181
            +D EESS+D KK   ++ S K +  VK+        S ++K   ++SSSSS +     +S
Sbjct: 1156 SDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNS 1215

Query: 182  SGSGTD--------------------CLDAGS-----------DSHLSDSSPSSKSSKKH 210
             G G+                     C  +G            D    D+ P ++ +KK 
Sbjct: 1216 IGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKM 1275

Query: 211  V------------SGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSP- 257
            +             G +   P+   K   K  E  P     K     E   D+     P 
Sbjct: 1276 LLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPR 1335

Query: 258  ---------LSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAA 308
                     L+  D    +  +      ++VK + +  VS E  ED  D + +    + +
Sbjct: 1336 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED-SDFQESGVSEEVS 1394

Query: 309  KKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQ 368
            +   E+     S+K + + ++   ++ K+K            +  +Q D     K + ++
Sbjct: 1395 ESEDEQRPRTRSAKKAELEENQRSYKQKKK----------RRRIKVQEDSSSENKSNSEE 1444

Query: 369  PSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNR 428
                        +EE  + + E +   ++ +  ++ PG      R      KL     N 
Sbjct: 1445 EEE--------EKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNA 1496

Query: 429  QKEQQ----RI-----ERENLALLKRLEAVKPT-----------VGMKRSEQLMDYHRNM 468
             KE++    RI     ERE L  +  +E   PT              +  E L+  HRNM
Sbjct: 1497 LKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNM 1556



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 44/182 (24%), Positives = 77/182 (42%), Gaps = 34/182 (18%)

Query: 34   DKQNDDPKERIDK----DTKNVNSNTGMQTTENYLTEKGNERNVKFPPEHPVENDVTQTV 89
            D  ++DP+ RI K    +    N ++    + +   E+G +R  K   E+P + +    V
Sbjct: 1261 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1320

Query: 90   SSFSLPASSRSKK-------------LCDVTTG------LKIHVSIPNRIPKIV--KEGE 128
            +S S   S  SKK             + D  +G       K H  +  R  + V  ++ E
Sbjct: 1321 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE 1380

Query: 129  D-DYYTDG--EESSDDGKKYHVKSKSAKPS------TNVKKSIRKKYCKVSSSSSSSLSS 179
            D D+   G  EE S+   +   +++SAK +       + K+  +++  KV   SSS   S
Sbjct: 1381 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1440

Query: 180  SS 181
            +S
Sbjct: 1441 NS 1442


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 68/320 (21%), Positives = 124/320 (38%), Gaps = 30/320 (9%)

Query: 73   VKFPPEHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVS-IPNRIPKIVKEGEDDY 131
            VK  P H     V  ++S    P+SS     C  T  L+  +S   N +  +V    D  
Sbjct: 1704 VKQMPGHAEVALVNGSISPLKYPSSSTLINGCKATATLQEKISSATNSVSSVVSAATDTV 1763

Query: 132  YTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDA 191
                              K    +T +  S  + Y   + S+  SL + S+ +    L  
Sbjct: 1764 -----------------EKVFSTTTAMPFSPLRSYVSAAPSAFQSLRTPSASALYTSL-- 1804

Query: 192  GSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDT 251
            GS    + SS +S      V  +  + P+   K   K  ++   + +      P ++  T
Sbjct: 1805 GSSISATTSSVTSSIITVPVYSVVNVLPEPALK---KLPDSNSFTKSAAALLSPIKTLTT 1861

Query: 252  VTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDV----EDLKNNSKYLKA 307
             T   P  +   SP++S      +  K+      + SQEI +DV    EDL   +  L+ 
Sbjct: 1862 ETHPQPHFSRTSSPVKSSLFLAPSALKLSTPSSLSSSQEILKDVAEMKEDLMRMTAILQT 1921

Query: 308  AKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFD 367
                ++  +P++  +    +D     +  +KV  D + ++ +LK  + +D KG  K    
Sbjct: 1922 DVPEEKPFQPELPKEGR--IDDEEPFKIVEKVKEDLVKVSEILKKDVCVDNKGSPKSPKS 1979

Query: 368  QPSVAPGKNY-SFTREEVRQ 386
                +P  ++  F+ EE+R+
Sbjct: 1980 DKGHSPEDDWIEFSSEEIRE 1999


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 65/320 (20%), Positives = 122/320 (38%), Gaps = 26/320 (8%)

Query: 142  GKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSS-----SSLSSSSSGSGTDCLDAGSDSH 196
            GK+   K  + +P      S++ +     S S      S+LSSS+       +   S + 
Sbjct: 1793 GKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTE 1852

Query: 197  L-SDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDV 255
              S  SPS+K+ +   +  +  + KH   S    TE     ++ K   +P  S    TD 
Sbjct: 1853 KHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDK 1912

Query: 256  SPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEKH 315
             P  +P     +   +     +K ++    +   + ++ V       K+L  +  GK + 
Sbjct: 1913 RPPVSPSGRTEKHPPVSPGRTEK-RLPVSPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEK 1971

Query: 316  EPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGK 375
            +P VS  S            K + + +TM +  L+KAF     + P KH          K
Sbjct: 1972 QPPVSPTS------------KTERIEETMSVRELMKAF--QSGQDPSKHKTGLFEHKSAK 2017

Query: 376  NYSFTREEVRQIDRE-----NQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNRQK 430
                  +   ++++E      QR  ++   Q  K G +  +  +A+    +  S++  +K
Sbjct: 2018 QKQPQEKGKVRVEKEKGPILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKK 2077

Query: 431  EQQRIERENLALLKRLEAVK 450
            E     +E +   K  E V+
Sbjct: 2078 EDAAGGKEKVLSHKIPEPVQ 2097



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 71/313 (22%), Positives = 112/313 (35%), Gaps = 50/313 (15%)

Query: 135  GEESSDDGK-----KYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSS------SG 183
            G  S  +GK     +     K  KPS  +KK +R+K  +        L +S+       G
Sbjct: 1672 GRSSEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEKQKQKEEGLQASAEKAELKKG 1731

Query: 184  SGTDCLDAGSDSHLS-DSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCG 242
            S  + L  G D  L+ +  P+ K++   +    + S K K K+  K  E +    + K  
Sbjct: 1732 SSEESL--GEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRS-KLP 1788

Query: 243  HYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQ----EIYEDVEDL 298
               +  ED     +    P  SP    E         K ++   +S     E +  V   
Sbjct: 1789 IRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPS 1848

Query: 299  KNNSKYLKAAKKGK-EKHEPDVSS----KSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAF 353
                K+   +   K E+H P  SS    K S V  S+   RH   V     + +  +   
Sbjct: 1849 SKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERH-SPVSSTKTERHPPVSPS 1907

Query: 354  LQLDKKGP-------QKHHFDQPSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPG 406
             + DK+ P       +KH    P V+PG              R  +RL    S + +K  
Sbjct: 1908 GKTDKRPPVSPSGRTEKH----PPVSPG--------------RTEKRLPVSPSGRTDKHQ 1949

Query: 407  SKSTIPRSADHPP 419
              ST  ++  H P
Sbjct: 1950 PVSTAGKTEKHLP 1962


>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
          Length = 953

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 94/459 (20%), Positives = 158/459 (34%), Gaps = 89/459 (19%)

Query: 42  ERIDKDTKNVNSNTGMQTTENYLTEKGNERNVKFPPEHPVENDVTQTVSSFSLPASSRSK 101
           ER D +   +       +  + L E  +E   + P E P              P +  SK
Sbjct: 304 ERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPS-------------PEARDSK 350

Query: 102 KLCDVTTGLKIHVSIPNRIPKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKS 161
           +      G K      N +P   KE          E +D       K  S K   ++K  
Sbjct: 351 E-----DGRKFDFDACNEVPPAPKESSTS------EGADQ------KMSSFKEEKDIKPI 393

Query: 162 IRKKYCKVSSSSSSSLSSSSSGSGTDCLD-----------AGSDSHLSDSSPSSK----- 205
           I+ +  +V S S  +L  S   S T   D            G+    +  SP ++     
Sbjct: 394 IKDEKGRVGSGSGRNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFV 453

Query: 206 SSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISP 265
           +          +S  H+ +   +    + +   P      +  E    +V       +  
Sbjct: 454 TMSTSDEATKCISHLHRTELHGRMISVEKAKNEPAGKKLSDRKE---CEVKKEKLSSVDR 510

Query: 266 LQSFELGIANDQKVKIKKQENVSQEIYEDVEDLK--------------NNSKYLKAAKKG 311
             S E+ I   +K  IKK+E + ++  +  ED+K              N S+  K+  +G
Sbjct: 511 HHSVEIKI---EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRG 567

Query: 312 KEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSV 371
            E+      SK   V+      R K++             +    D+K   K   D  S 
Sbjct: 568 MERTVVMDKSKGEPVISVKTTSRSKER-------------SSKSQDRKSESKEKRDILSF 614

Query: 372 APGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPK----LYHSALN 427
              K     RE  RQ  R+ +R ++E  R+ E+   +      A H  K    L    L 
Sbjct: 615 DKIKEQ---RERERQ--RQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQ 669

Query: 428 RQKEQQRIERENLALLKRLEAVKPTVGMKRSEQLMDYHR 466
            + ++QR+ERE +   +RLE  +  V  +R ++    HR
Sbjct: 670 LECQRQRLERERME-RERLERERMRVERERRKEQERIHR 707


>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 86/359 (23%), Positives = 141/359 (39%), Gaps = 60/359 (16%)

Query: 141 DGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSS-SLSSSSSGSGTDCLDAGSD--SHL 197
           + +K   KS   +PS  V+   R      SSSSSS S SSSS  S +D  D+ S+     
Sbjct: 614 NSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSESEMFPKF 673

Query: 198 SDSSPSSKSSKKHV-------------SGITLLSPKHKYKSGIKST---ETQPSSTTPKC 241
           ++  P+   SK++V             +G+T +    +  +   +T   +T PS   P  
Sbjct: 674 TEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPN 733

Query: 242 GH-----YPE-ESEDTVTDVSPLS-TPDISPLQSFELGI-----ANDQKVKIKKQENVSQ 289
            H     Y E E   TV ++SPL   P     +    GI     + D    + + E    
Sbjct: 734 HHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGDSDTTMLESE-CQA 792

Query: 290 EIYEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHL 349
            + +D++ +KN   +    K  K    P    KSS  L +       +K +        L
Sbjct: 793 PVQKDIK-IKNADSWKSLGKPVK----PSGVMKSSDELFNQFRKAAIEKEV--KARTQEL 845

Query: 350 LKAFLQLDKKGPQKHHFDQPSVAPGKNY-SFTREEVRQIDRENQRLLKELSRQAEKPGSK 408
           ++  L+ + K  +    +Q  +  G    SF+ +   +   E Q+  ++ S   +K  SK
Sbjct: 846 IRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQDK--SK 903

Query: 409 STIPRSADHPPKLYHSALNRQKEQQRIERENLALLKRLEAVKPTVGMKRSEQLMDYHRN 467
             + +  D         L RQKEQ+R         +R EA+  T+ M     +M    N
Sbjct: 904 LWLLKDRD---------LARQKEQER---------RRREAMVGTIDMTLQSDIMTMFEN 944


>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 86/359 (23%), Positives = 141/359 (39%), Gaps = 60/359 (16%)

Query: 141 DGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSS-SLSSSSSGSGTDCLDAGSD--SHL 197
           + +K   KS   +PS  V+   R      SSSSSS S SSSS  S +D  D+ S+     
Sbjct: 614 NSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSESEMFPKF 673

Query: 198 SDSSPSSKSSKKHV-------------SGITLLSPKHKYKSGIKST---ETQPSSTTPKC 241
           ++  P+   SK++V             +G+T +    +  +   +T   +T PS   P  
Sbjct: 674 TEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPN 733

Query: 242 GH-----YPE-ESEDTVTDVSPLS-TPDISPLQSFELGI-----ANDQKVKIKKQENVSQ 289
            H     Y E E   TV ++SPL   P     +    GI     + D    + + E    
Sbjct: 734 HHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGDSDTTMLESE-CQA 792

Query: 290 EIYEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHL 349
            + +D++ +KN   +    K  K    P    KSS  L +       +K +        L
Sbjct: 793 PVQKDIK-IKNADSWKSLGKPVK----PSGVMKSSDELFNQFRKAAIEKEV--KARTQEL 845

Query: 350 LKAFLQLDKKGPQKHHFDQPSVAPGKNY-SFTREEVRQIDRENQRLLKELSRQAEKPGSK 408
           ++  L+ + K  +    +Q  +  G    SF+ +   +   E Q+  ++ S   +K  SK
Sbjct: 846 IRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQDK--SK 903

Query: 409 STIPRSADHPPKLYHSALNRQKEQQRIERENLALLKRLEAVKPTVGMKRSEQLMDYHRN 467
             + +  D         L RQKEQ+R         +R EA+  T+ M     +M    N
Sbjct: 904 LWLLKDRD---------LARQKEQER---------RRREAMVGTIDMTLQSDIMTMFEN 944


>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
           sapiens]
          Length = 858

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/146 (24%), Positives = 54/146 (36%), Gaps = 16/146 (10%)

Query: 132 YTDGEESSDDGKKYHVKSKSAK------------PSTNVKKSIRKKYCKVSSSSSSSLSS 179
           +T G +    GKK+H K   +             PS    K  R+   +  S  SSSL S
Sbjct: 679 HTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDS 738

Query: 180 SSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTP 239
             SG           SHL  +    + +KK        + K ++KS    +ET P     
Sbjct: 739 VESGGAALGGRGSPSSHLLGADHGLRKAKKPKKK----TKKRRHKSNSPESETDPEEKAG 794

Query: 240 KCGHYPEESEDTVTDVSPLSTPDISP 265
           K     E+ +D   ++     P+ SP
Sbjct: 795 KESDEKEQEQDKDRELQQAELPNRSP 820


>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
           sapiens]
          Length = 871

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/146 (24%), Positives = 54/146 (36%), Gaps = 16/146 (10%)

Query: 132 YTDGEESSDDGKKYHVKSKSAK------------PSTNVKKSIRKKYCKVSSSSSSSLSS 179
           +T G +    GKK+H K   +             PS    K  R+   +  S  SSSL S
Sbjct: 692 HTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDS 751

Query: 180 SSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTP 239
             SG           SHL  +    + +KK        + K ++KS    +ET P     
Sbjct: 752 VESGGAALGGRGSPSSHLLGADHGLRKAKKPKKK----TKKRRHKSNSPESETDPEEKAG 807

Query: 240 KCGHYPEESEDTVTDVSPLSTPDISP 265
           K     E+ +D   ++     P+ SP
Sbjct: 808 KESDEKEQEQDKDRELQQAELPNRSP 833


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/185 (22%), Positives = 84/185 (45%), Gaps = 28/185 (15%)

Query: 275 NDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAA------KKGKEKHEPDVSSKSSSVLD 328
           +++++KI +QEN  + + + V  L+  S+    A      K+ K  HE  +   SS +  
Sbjct: 549 SERQIKILEQEN--EHLNQTVSSLRQRSQISAEARVKDIEKENKILHE-SIKETSSKLSK 605

Query: 329 SSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGK---NYSFTREEVR 385
              + R  +K      +L H  +   + ++   + HH ++ +    K   N   T E++ 
Sbjct: 606 IEFEKRQIKK------ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIE 659

Query: 386 QIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQQRIERENLALLKR 445
            +++EN     EL R+  K      + ++ D    L     + +KE  +++ ENL L + 
Sbjct: 660 ALEQENS----ELERENRK------LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709

Query: 446 LEAVK 450
           +E++K
Sbjct: 710 VESLK 714


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/185 (22%), Positives = 84/185 (45%), Gaps = 28/185 (15%)

Query: 275 NDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAA------KKGKEKHEPDVSSKSSSVLD 328
           +++++KI +QEN  + + + V  L+  S+    A      K+ K  HE  +   SS +  
Sbjct: 549 SERQIKILEQEN--EHLNQTVSSLRQRSQISAEARVKDIEKENKILHE-SIKETSSKLSK 605

Query: 329 SSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGK---NYSFTREEVR 385
              + R  +K      +L H  +   + ++   + HH ++ +    K   N   T E++ 
Sbjct: 606 IEFEKRQIKK------ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIE 659

Query: 386 QIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQQRIERENLALLKR 445
            +++EN     EL R+  K      + ++ D    L     + +KE  +++ ENL L + 
Sbjct: 660 ALEQENS----ELERENRK------LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709

Query: 446 LEAVK 450
           +E++K
Sbjct: 710 VESLK 714



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 56/295 (18%), Positives = 123/295 (41%), Gaps = 32/295 (10%)

Query: 227  IKSTETQPSSTTPKCGHYPE------ESEDTVTDVSPLSTPDISPLQSFELGIANDQKVK 280
            I + E +  + + + G Y E      E E    ++   +T DI  L +    + ++ K+K
Sbjct: 859  IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSE-KLK 917

Query: 281  IKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKV- 339
             ++  N  +++  ++E +  N + L   ++  +     + SK  S L  SL+ + ++   
Sbjct: 918  TQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAA 977

Query: 340  ----LHDTMDLNHLLKAFLQLDKKGPQ--KHHFDQPSVAP------GKNYSFTREE---V 384
                L ++ + N  L+  L+  KK  +  K   D+  +        G++  + RE     
Sbjct: 978  LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETT 1037

Query: 385  RQIDRENQRLLK----ELSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQQRIERENL 440
            R++ +   RL++      + QAEK   K+ + +       L    L  Q++   ++ +N 
Sbjct: 1038 RELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNT 1097

Query: 441  ALL---KRLEAVKPTVGMKRSEQLMDYHRNMGYLNSSPLSRRARSTLGQYSPLRA 492
             L     +L+    T+   +S  LM+ +  +  +  S L     S + +   L++
Sbjct: 1098 TLQTQNAKLQVENSTLN-SQSTSLMNQNAQL-LIQQSSLENENESVIKEREDLKS 1150


>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo
           sapiens]
          Length = 1555

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 47/256 (18%), Positives = 102/256 (39%), Gaps = 19/256 (7%)

Query: 198 SDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQP-----------SSTTPKCG---- 242
           S+  P S  SK HVS I  ++ K  ++  ++S +++P           ++  P+      
Sbjct: 245 SNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLNRISQ 304

Query: 243 --HYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKV-KIKKQENVSQEIYEDVEDLK 299
             H  ++S      ++ L+  D    ++      N  K  K K  E ++++  + ++   
Sbjct: 305 HSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKELDQLDSKS 364

Query: 300 NNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKK 359
            +     +  K K  H  D+ ++ S  +  S  ++   ++     D        ++  +K
Sbjct: 365 KSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVKEKRK 424

Query: 360 GPQKHHFDQPSVAPGKNYSFTREEV-RQIDRENQRLLKELSRQAEKPGSKSTIPRSADHP 418
             +K   D+   +     + +R ++   I ++   + +E  +Q  KPG  ST  RS    
Sbjct: 425 TAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRSRSRS 484

Query: 419 PKLYHSALNRQKEQQR 434
           PK     ++  K + R
Sbjct: 485 PKSRSPIIHSPKRRDR 500


>gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]
          Length = 601

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 60/255 (23%), Positives = 101/255 (39%), Gaps = 24/255 (9%)

Query: 84  DVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIVKEGEDDYYTDGEESSDDGK 143
           D+ + ++S     S  SKK  + ++G   H        +    G     + GE   +DG 
Sbjct: 111 DLLKAITSPLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSG-----SSGELPLEDGG 165

Query: 144 KYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPS 203
            +  KSK  KP     +++     +        L  S    G+  +D  S  + S  +  
Sbjct: 166 SH--KSKKMKPLYVNTETLT---LREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATV 220

Query: 204 SKSSKKHV---SGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLST 260
            KSSKK      G  LL   H+ +S +K+   +  S++    H     E   +D S  + 
Sbjct: 221 KKSSKKSARDEQGALLLG--HELQSFLKTARKKHKSSSD--AHSSPGPEGCGSDASQFAE 276

Query: 261 P-----DISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEKH 315
                 D+S L+   +   +    +++  E V  + Y +++  K + K  K  KK KEKH
Sbjct: 277 SHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKK--KKDKEKH 334

Query: 316 EPDVSSKSSSVLDSS 330
           +    SKS   L  S
Sbjct: 335 KEKRHSKSKRSLGLS 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.124    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,705,302
Number of Sequences: 37866
Number of extensions: 1013056
Number of successful extensions: 7292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 5483
Number of HSP's gapped (non-prelim): 1303
length of query: 532
length of database: 18,247,518
effective HSP length: 107
effective length of query: 425
effective length of database: 14,195,856
effective search space: 6033238800
effective search space used: 6033238800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.