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Search of human proteins with 149363636
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149363636 plexin B2 [Homo sapiens]
(1838 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149363636 plexin B2 [Homo sapiens] 3731 0.0
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 1210 0.0
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 1210 0.0
gi|194272180 plexin B1 [Homo sapiens] 988 0.0
gi|40254442 plexin B1 [Homo sapiens] 988 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 936 0.0
gi|49355818 plexin A1 [Homo sapiens] 932 0.0
gi|157694524 plexin D1 [Homo sapiens] 929 0.0
gi|113722116 plexin A2 [Homo sapiens] 924 0.0
gi|59710104 plexin A3 [Homo sapiens] 893 0.0
gi|5032223 plexin C1 [Homo sapiens] 407 e-113
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 157 9e-38
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 156 2e-37
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 111 7e-24
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 96 2e-19
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 96 2e-19
gi|16306552 semaphorin Y [Homo sapiens] 75 8e-13
gi|19718780 semaphorin 6B precursor [Homo sapiens] 74 1e-12
gi|21361914 semaphorin B [Homo sapiens] 70 2e-11
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 67 2e-10
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 67 2e-10
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 67 2e-10
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 67 2e-10
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 67 2e-10
gi|28872814 semaphorin 4G [Homo sapiens] 64 1e-09
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 64 2e-09
gi|39777610 semaphorin 4B precursor [Homo sapiens] 62 5e-09
gi|39777608 semaphorin 4B precursor [Homo sapiens] 62 5e-09
gi|157388902 semaphorin 4C [Homo sapiens] 62 7e-09
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 59 6e-08
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 3731 bits (9674), Expect = 0.0
Identities = 1838/1838 (100%), Positives = 1838/1838 (100%)
Query: 1 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 60
MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK
Sbjct: 1 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 60
Query: 61 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 120
LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC
Sbjct: 61 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 120
Query: 121 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 180
ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG
Sbjct: 121 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 180
Query: 181 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 240
IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA
Sbjct: 181 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 240
Query: 241 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 300
RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD
Sbjct: 241 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 300
Query: 301 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 360
SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK
Sbjct: 301 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 360
Query: 361 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 420
SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL
Sbjct: 361 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 420
Query: 421 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 480
TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD
Sbjct: 421 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 480
Query: 481 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 540
SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT
Sbjct: 481 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 540
Query: 541 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 600
VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR
Sbjct: 541 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 600
Query: 601 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 660
GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA
Sbjct: 601 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 660
Query: 661 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 720
HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT
Sbjct: 661 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 720
Query: 721 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 780
FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA
Sbjct: 721 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 780
Query: 781 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 840
WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV
Sbjct: 781 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 840
Query: 841 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 900
AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV
Sbjct: 841 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 900
Query: 901 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 960
EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML
Sbjct: 901 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 960
Query: 961 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 1020
LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA
Sbjct: 961 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 1020
Query: 1021 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1080
EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA
Sbjct: 1021 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1080
Query: 1081 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1140
LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK
Sbjct: 1081 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1140
Query: 1141 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1200
TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL
Sbjct: 1141 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1200
Query: 1201 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1260
ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM
Sbjct: 1201 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1260
Query: 1261 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1320
EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS
Sbjct: 1261 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1320
Query: 1321 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1380
NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY
Sbjct: 1321 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1380
Query: 1381 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1440
VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV
Sbjct: 1381 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1440
Query: 1441 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1500
QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR
Sbjct: 1441 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1500
Query: 1501 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1560
GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK
Sbjct: 1501 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1560
Query: 1561 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1620
VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI
Sbjct: 1561 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1620
Query: 1621 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1680
YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK
Sbjct: 1621 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1680
Query: 1681 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1740
TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL
Sbjct: 1681 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1740
Query: 1741 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1800
YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK
Sbjct: 1741 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1800
Query: 1801 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1838
YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL
Sbjct: 1801 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1838
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 1210 bits (3131), Expect = 0.0
Identities = 764/1901 (40%), Positives = 1049/1901 (55%), Gaps = 141/1901 (7%)
Query: 34 LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93
LNHLA+ G +Y+GAVN L+QL +LQLE TGP +D+ C P + ++C +A++T
Sbjct: 77 LNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLT 136
Query: 94 DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153
DN NQLLL+ + LV CG + +G+C R L +++ L+ + G+ FVA+N GVAT
Sbjct: 137 DNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVAT 196
Query: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGYLST 213
VGLV PG D +L G G V + + + F + G S
Sbjct: 197 VGLVVPL-PGRDLLLVARGLAGKLSAG--VPPLAIRQLAGSQPFSS-EGLGRLVVGDFSD 252
Query: 214 NTQQFVAAFEDGPYVFFVFNQQD-KHPARNRTLLARMCREDPNYYSYLEMDLQCRDPDIH 272
+V AF D +FVF ++ + A R+ +AR+C D N YSY+E+ L C+ +
Sbjct: 253 YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLI 312
Query: 273 AAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNACYT 332
AAF APG+ L VF+ R G A LC FP+ ++ A ME R CYT
Sbjct: 313 QAAF--------LAPGT---LLGVFAAGPR---GTQAALCAFPMVELGASMEQARRLCYT 358
Query: 333 -------GTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVL 385
G EA + +C S +S+PCG EH P P+ R L +L
Sbjct: 359 AGGRGPSGAEEAT----VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLL 414
Query: 386 QRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLV 445
+ G ++AV + H +AFLG + G++ KV+L + + + DL+
Sbjct: 415 KLGQ-PVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLL 473
Query: 446 LSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAE 505
L LY +T +V R+PV C +P C C +QDP CGWCV++GRCTRK +C RA
Sbjct: 474 LDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAG 533
Query: 506 EASHWLWSRSKS--CVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPH 563
+ + WLWS + C+ + S P + R+ QG+V L+V LP L ++ C FG+
Sbjct: 534 QLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSL 593
Query: 564 PARVEGEAVICNSP--SSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSL 621
A VEG V C +P +P+ PPG DHV V + L+ + T++ FYDC +L
Sbjct: 594 -AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFS--FYDCSAVQAL 650
Query: 622 EENLPCISCVSNRWTCQWDLRYHEC--REASPNPEDGIVRAHMED-------SCPQFLG- 671
E PC +CV + W C W + C E P E I A D +CPQ G
Sbjct: 651 EAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGL 710
Query: 672 PSPLVIPMNHETDVNFQGKNLDTVKG--SSLHVGSDLLKFME--PVTMQESGTFAFRTPK 727
P ++P+ E+ + + +NL +G +S H +L + P T++E+ +
Sbjct: 711 AGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHC 770
Query: 728 LSHD-----ANETLPLHLYV-KSYGKNIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRC 779
+H + LP+ +YV + + +D+ L+V LY+C+ G DCS C+AAN C
Sbjct: 771 QAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGC 830
Query: 780 AWCG-GQSRCVYEALCNTTSE---CPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI 835
WC GQ C Y LC + CP P I ++P TGP GG+ +TILGSNLG D+
Sbjct: 831 LWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADV 890
Query: 836 Q-RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQ---FT 891
Q +SVA R C+ +P Y S RIVCV A TG V V + + PP + FT
Sbjct: 891 QYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQ----PPGISSQHFT 946
Query: 892 FQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTK--FGAQLQCV 949
+Q P LS+ P+ GPQAGGT LTI G HL TG V G PC + + + C
Sbjct: 947 YQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFV--GGQPCPILEPVCPEAIVCR 1004
Query: 950 TGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFS 1009
T PQA G+ + V +G + F Y NP L A EP SF GGR I V G G
Sbjct: 1005 TRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLD 1064
Query: 1010 LIQRFAMVVIAEP----------LQSWQPPRE--AESLQPMTVV---------GTDYVFH 1048
++QR + V E Q QP R A + P + T +
Sbjct: 1065 VVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVN 1124
Query: 1049 NDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGA--FEYVPDPTF-----ENFT 1101
+ + ++ SPAVP+ A+ V +D + + +G F Y P+P E
Sbjct: 1125 SSSLLLCRSPAVPDR--AHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPA 1182
Query: 1102 GGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRR 1161
+ + ++ G LN ++ +E +G C +KTLT T LYCEPP P P
Sbjct: 1183 RPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANG 1242
Query: 1162 QKRDTTHNLPEFIVKFGSREWVLGRVEYDTR--VSDVPLSLILPLVIVPMVVVIAVSVYC 1219
LP+F+V+ G+ + LG V+Y+ +S P+ + + V++ AV +
Sbjct: 1243 S------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLT 1296
Query: 1220 --YWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDY 1277
Y KS+QA R+Y+K+ QLE LE V D+C+KEFTDLM EM D ++D+ +GIP LDY
Sbjct: 1297 LMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDY 1356
Query: 1278 KTYTDRVFFLPSKDGDKDVMITGKLDIP--EPRRPVVEQALYQFSNLLNSKSFLINFIHT 1335
+TY +R FF G + K + P + V Q L Q SNLLNSK FL+ IHT
Sbjct: 1357 RTYAERAFF----PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHT 1412
Query: 1336 LENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSET 1395
LE Q FS R + + ASLL++ALHGKLEY TDIM TL +L YV +NPKLMLRR+ET
Sbjct: 1413 LEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYV-HRNPKLMLRRTET 1471
Query: 1396 VVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLG 1455
+VE++L+NW+SICLY +L++ AGEPLY LF+AI++QV+KGPVDAV KAK TLND+ LL
Sbjct: 1472 MVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLR 1531
Query: 1456 DDVEYAPLTVSVIVQ--------DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCW 1507
+DVE+ PLT+ V+V + +P +VL+ DTI+QVKEK++DQVY+G P S
Sbjct: 1532 EDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQR 1591
Query: 1508 PRPDSVVLEWRPGSTAQI-LSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKV---GV 1563
P ++ LEWR G + LSD DLTS + WKR+NTL HY V DGAT+ L G
Sbjct: 1592 PSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGS 1651
Query: 1564 SQQPEDSQQDLPGERHALLEEENR----VWHLVRPTDEVDEGKSKRGSVKEKE--RTKAI 1617
+ +Q+ GE LE+ +WHLV+ T+E + K + S++E+E R KAI
Sbjct: 1652 TISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAI 1711
Query: 1618 TEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIH 1677
EIYLTRLLS+KGTLQ+FVD+ FQ++L+ +P AVKY FD LDE AEKH I+D T+H
Sbjct: 1712 PEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLH 1771
Query: 1678 IWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSN 1737
IWKTNSL LRFWVN LKNP IFDV V + VDA L+VIAQTF+D+CT +EHK+ RDSP N
Sbjct: 1772 IWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVN 1831
Query: 1738 KLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQY 1797
KLLYA+EI YK+MVE YY IRQ S Q+MN+ LAE+S +T + + L AL +LY +
Sbjct: 1832 KLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNH 1891
Query: 1798 TQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1838
+YYD+II+ALEEDP QK+QLA RLQQ+AA +ENKVTDL
Sbjct: 1892 IHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 1210 bits (3131), Expect = 0.0
Identities = 764/1901 (40%), Positives = 1049/1901 (55%), Gaps = 141/1901 (7%)
Query: 34 LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93
LNHLA+ G +Y+GAVN L+QL +LQLE TGP +D+ C P + ++C +A++T
Sbjct: 54 LNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLT 113
Query: 94 DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153
DN NQLLL+ + LV CG + +G+C R L +++ L+ + G+ FVA+N GVAT
Sbjct: 114 DNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVAT 173
Query: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGYLST 213
VGLV PG D +L G G V + + + F + G S
Sbjct: 174 VGLVVPL-PGRDLLLVARGLAGKLSAG--VPPLAIRQLAGSQPFSS-EGLGRLVVGDFSD 229
Query: 214 NTQQFVAAFEDGPYVFFVFNQQD-KHPARNRTLLARMCREDPNYYSYLEMDLQCRDPDIH 272
+V AF D +FVF ++ + A R+ +AR+C D N YSY+E+ L C+ +
Sbjct: 230 YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLI 289
Query: 273 AAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNACYT 332
AAF APG+ L VF+ R G A LC FP+ ++ A ME R CYT
Sbjct: 290 QAAF--------LAPGT---LLGVFAAGPR---GTQAALCAFPMVELGASMEQARRLCYT 335
Query: 333 -------GTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVL 385
G EA + +C S +S+PCG EH P P+ R L +L
Sbjct: 336 AGGRGPSGAEEAT----VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLL 391
Query: 386 QRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLV 445
+ G ++AV + H +AFLG + G++ KV+L + + + DL+
Sbjct: 392 KLGQ-PVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLL 450
Query: 446 LSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAE 505
L LY +T +V R+PV C +P C C +QDP CGWCV++GRCTRK +C RA
Sbjct: 451 LDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAG 510
Query: 506 EASHWLWSRSKS--CVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPH 563
+ + WLWS + C+ + S P + R+ QG+V L+V LP L ++ C FG+
Sbjct: 511 QLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSL 570
Query: 564 PARVEGEAVICNSP--SSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSL 621
A VEG V C +P +P+ PPG DHV V + L+ + T++ FYDC +L
Sbjct: 571 -AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFS--FYDCSAVQAL 627
Query: 622 EENLPCISCVSNRWTCQWDLRYHEC--REASPNPEDGIVRAHMED-------SCPQFLG- 671
E PC +CV + W C W + C E P E I A D +CPQ G
Sbjct: 628 EAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGL 687
Query: 672 PSPLVIPMNHETDVNFQGKNLDTVKG--SSLHVGSDLLKFME--PVTMQESGTFAFRTPK 727
P ++P+ E+ + + +NL +G +S H +L + P T++E+ +
Sbjct: 688 AGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHC 747
Query: 728 LSHD-----ANETLPLHLYV-KSYGKNIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRC 779
+H + LP+ +YV + + +D+ L+V LY+C+ G DCS C+AAN C
Sbjct: 748 QAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGC 807
Query: 780 AWCG-GQSRCVYEALCNTTSE---CPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI 835
WC GQ C Y LC + CP P I ++P TGP GG+ +TILGSNLG D+
Sbjct: 808 LWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADV 867
Query: 836 Q-RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQ---FT 891
Q +SVA R C+ +P Y S RIVCV A TG V V + + PP + FT
Sbjct: 868 QYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQ----PPGISSQHFT 923
Query: 892 FQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTK--FGAQLQCV 949
+Q P LS+ P+ GPQAGGT LTI G HL TG V G PC + + + C
Sbjct: 924 YQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFV--GGQPCPILEPVCPEAIVCR 981
Query: 950 TGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFS 1009
T PQA G+ + V +G + F Y NP L A EP SF GGR I V G G
Sbjct: 982 TRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLD 1041
Query: 1010 LIQRFAMVVIAEP----------LQSWQPPRE--AESLQPMTVV---------GTDYVFH 1048
++QR + V E Q QP R A + P + T +
Sbjct: 1042 VVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVN 1101
Query: 1049 NDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGA--FEYVPDPTF-----ENFT 1101
+ + ++ SPAVP+ A+ V +D + + +G F Y P+P E
Sbjct: 1102 SSSLLLCRSPAVPDR--AHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPA 1159
Query: 1102 GGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRR 1161
+ + ++ G LN ++ +E +G C +KTLT T LYCEPP P P
Sbjct: 1160 RPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANG 1219
Query: 1162 QKRDTTHNLPEFIVKFGSREWVLGRVEYDTR--VSDVPLSLILPLVIVPMVVVIAVSVYC 1219
LP+F+V+ G+ + LG V+Y+ +S P+ + + V++ AV +
Sbjct: 1220 S------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLT 1273
Query: 1220 --YWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDY 1277
Y KS+QA R+Y+K+ QLE LE V D+C+KEFTDLM EM D ++D+ +GIP LDY
Sbjct: 1274 LMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDY 1333
Query: 1278 KTYTDRVFFLPSKDGDKDVMITGKLDIP--EPRRPVVEQALYQFSNLLNSKSFLINFIHT 1335
+TY +R FF G + K + P + V Q L Q SNLLNSK FL+ IHT
Sbjct: 1334 RTYAERAFF----PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHT 1389
Query: 1336 LENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSET 1395
LE Q FS R + + ASLL++ALHGKLEY TDIM TL +L YV +NPKLMLRR+ET
Sbjct: 1390 LEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYV-HRNPKLMLRRTET 1448
Query: 1396 VVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLG 1455
+VE++L+NW+SICLY +L++ AGEPLY LF+AI++QV+KGPVDAV KAK TLND+ LL
Sbjct: 1449 MVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLR 1508
Query: 1456 DDVEYAPLTVSVIVQ--------DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCW 1507
+DVE+ PLT+ V+V + +P +VL+ DTI+QVKEK++DQVY+G P S
Sbjct: 1509 EDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQR 1568
Query: 1508 PRPDSVVLEWRPGSTAQI-LSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKV---GV 1563
P ++ LEWR G + LSD DLTS + WKR+NTL HY V DGAT+ L G
Sbjct: 1569 PSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGS 1628
Query: 1564 SQQPEDSQQDLPGERHALLEEENR----VWHLVRPTDEVDEGKSKRGSVKEKE--RTKAI 1617
+ +Q+ GE LE+ +WHLV+ T+E + K + S++E+E R KAI
Sbjct: 1629 TISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAI 1688
Query: 1618 TEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIH 1677
EIYLTRLLS+KGTLQ+FVD+ FQ++L+ +P AVKY FD LDE AEKH I+D T+H
Sbjct: 1689 PEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLH 1748
Query: 1678 IWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSN 1737
IWKTNSL LRFWVN LKNP IFDV V + VDA L+VIAQTF+D+CT +EHK+ RDSP N
Sbjct: 1749 IWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVN 1808
Query: 1738 KLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQY 1797
KLLYA+EI YK+MVE YY IRQ S Q+MN+ LAE+S +T + + L AL +LY +
Sbjct: 1809 KLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNH 1868
Query: 1798 TQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1838
+YYD+II+ALEEDP QK+QLA RLQQ+AA +ENKVTDL
Sbjct: 1869 IHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 988 bits (2553), Expect = 0.0
Identities = 555/1161 (47%), Positives = 740/1161 (63%), Gaps = 59/1161 (5%)
Query: 727 KLSHDANET-LPLHLYVKSYGK-NIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRCAWC 782
+LS++A + L + L+++ G+ +DS LHV LY+CS G DCS C+ A P Y C WC
Sbjct: 985 QLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVWC 1044
Query: 783 GGQS-RCVYEALCN----TTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQ- 836
G+ RCV C ++CP P+I ++P TGP+ GG R+TI GSNLG D+
Sbjct: 1045 EGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLG 1104
Query: 837 RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPK 896
++VAG C+ + Y VS+ +VC+ A+ G V+V G+ GR F +Q PK
Sbjct: 1105 MVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGR-GRGVSEHDFAYQDPK 1163
Query: 897 PLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT--KFGAQLQCVTGPQA 954
S+ P +GP+AGGT LT++G+ L TG ED+RV + PC + + QL+C T P+
Sbjct: 1164 VHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRP 1223
Query: 955 TRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQ-- 1012
T + + V +G + F Y +P + + P +SF SGGR I V GQ ++Q
Sbjct: 1224 TPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTP 1283
Query: 1013 RFAMVVIAEPLQSWQPPREAESLQPMTVVGT----------DYVFHNDTKVVFL-SPAVP 1061
R + V++ LQ Q + P T + N ++++ +PA+P
Sbjct: 1284 RIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVNSSQLITCRTPALP 1343
Query: 1062 EEPEAYNLTVLIEMDGHRALLRT-EAGAFEYVPDPTF-----ENFTGGVKKQVNKLIHAR 1115
PE + V +D T F Y DPT E+ T + + +
Sbjct: 1344 GLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVE 1403
Query: 1116 GTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIV 1175
G NL+ AM+ +E A +G C +KTLT LYCEPP QP P+ R+ +LPEF V
Sbjct: 1404 GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTV 1463
Query: 1176 KFGSREWVLGRVEYDTR-------VSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAE 1228
+ G+ + LG V+YD + V L + L+ + +++++ + Y RKS+QA
Sbjct: 1464 QMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLM----YRRKSKQAL 1519
Query: 1229 REYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLP 1288
R+Y+K++ QLE LE SVRDRCKKEFTDLM EM D T+D+ +GIP LDYK Y +R+FF
Sbjct: 1520 RDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFF-- 1577
Query: 1289 SKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKV 1348
G ++ + L +PE RRP VEQ L Q SNLLNSK FL FIHTLE+QR FSAR +
Sbjct: 1578 --PGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRA 1635
Query: 1349 YFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERMLSNWMSIC 1408
Y ASLLTVALHGKLEY+TDI+ TL +L+ QYV AKNPKLMLRR+ETVVE++L+NWMSIC
Sbjct: 1636 YVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKNPKLMLRRTETVVEKLLTNWMSIC 1694
Query: 1409 LYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVI 1468
LY +++DS GEPLY LF+ IKHQV+KGPVD+V KAKYTLND LL +DVEY PLT++ +
Sbjct: 1695 LYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNAL 1754
Query: 1469 VQ----DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQ 1524
+ +PVKVL+CDTISQ KEK++DQ+Y+G P + P P ++ +EWR G
Sbjct: 1755 LAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGH 1814
Query: 1525 -ILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLE 1583
ILSD D+TS+ +G W+R+NTL HY V DGAT+ L ++Q +PGER +LE
Sbjct: 1815 LILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLE 1874
Query: 1584 EEN----RVWHLVRPTDEVDEGKSKRGSVK--EKERTKAITEIYLTRLLSVKGTLQQFVD 1637
+ + R WHLV+P+DE + + +RGS++ E+ER KAI EIYLTRLLS+KGTLQ+FVD
Sbjct: 1875 DVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVD 1934
Query: 1638 NFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNILKNPH 1697
+ FQ +L+ VP AVKYFFD LDEQA++H I D+DTIHIWKTNSLPLRFW+NI+KNP
Sbjct: 1935 DLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQ 1994
Query: 1698 FIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYK 1757
F+FDV + +DA L VIAQTFMDACT +HKL RDSP NKLLYA++I YK+MVE YY
Sbjct: 1995 FVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYA 2054
Query: 1758 GIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQK 1817
IRQ V SDQ+MN+ LAE+S ++ L VALH+LY+Y KYYD+II ALEED AQK
Sbjct: 2055 DIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQK 2114
Query: 1818 MQLAFRLQQIAAALENKVTDL 1838
MQL +RLQQIAAA+ENKVTDL
Sbjct: 2115 MQLGYRLQQIAAAVENKVTDL 2135
Score = 417 bits (1072), Expect = e-116
Identities = 251/670 (37%), Positives = 350/670 (52%), Gaps = 41/670 (6%)
Query: 34 LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93
L HLA D SG +YLGA N L+QL LQLE V+TGP LD++ C PP+ +C +A+ T
Sbjct: 35 LQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT 94
Query: 94 DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153
+N NQLLL+ P LV CGS+ +G+C R L + L + G+ +VA+ND V+T
Sbjct: 95 NNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVST 152
Query: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNG---IIVSTRLLDRTDSREAFEAYTDHATYKAGY 210
VGLV+ G G+ +LFVG+G G ++TR L D + AF +Y + A G
Sbjct: 153 VGLVAQ-GLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQAAF-SYEETAKLAVGR 210
Query: 211 LSTNTQQFVAAFEDGPYVFFVFNQQDKHPARN--RTLLARMCREDPNYYSYLEMDLQCRD 268
LS + FV+AF G +F+F ++D R ++R+C D +YYSY+E+ L C
Sbjct: 211 LSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACE- 269
Query: 269 PDIHAAAFGTCLAASVAAP---GSGRVLYAVFSR---------DSRSSGGPGAG-LCLFP 315
+G AA+VA G VL+A FS S ++G GA LC FP
Sbjct: 270 ----GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFP 325
Query: 316 LDKVHAKMEANRNACYTGTREARD---IFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYP 372
LD+V R+ACYT A D + Y + + C + ++PCGS+H P P
Sbjct: 326 LDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSP 385
Query: 373 LGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSI 432
+ SR L T +L+ G+ LTAV V E+ HT+AFLG S G++ +VYL P Y +
Sbjct: 386 MASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQ 445
Query: 433 LVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVE 492
++ V RDL G LY MTQ + ++PV C + C C +DPYCGWCV+
Sbjct: 446 SIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLL 505
Query: 493 GRCTRKAECPRAEEASHWLWS--RSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEE 550
GRC+R++EC R + WLWS C+ V + P N+SR EV L+V LP L
Sbjct: 506 GRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPG 565
Query: 551 DELLCLFGESPPHPARVEGEAVICNS--PSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSY 608
+ C FGE PA + G V+C S PS PV P G D+V+V+++ LR G + +
Sbjct: 566 ESYSCHFGEH-QSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVE--LRFGAVVIAKT 622
Query: 609 QYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAH----MED 664
FYDC L + C +CVS+RW C W + H C + +V +H +
Sbjct: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSP 682
Query: 665 SCPQFLGPSP 674
P GPSP
Sbjct: 683 DPPARGGPSP 692
Score = 34.7 bits (78), Expect = 0.88
Identities = 48/215 (22%), Positives = 75/215 (34%), Gaps = 33/215 (15%)
Query: 620 SLEENLPCISCVSNRWT-CQWDLRYHECREASP-----NPEDGIVRAHMEDSCPQFLGPS 673
S ++L C SC+++R C W + C S PE + E C Q S
Sbjct: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
Query: 674 PLVIPMNHETDVNFQGKNLDTV---KGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSH 730
P I +V +L + + S H G + P + SG P
Sbjct: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFG----EHQSPALLTGSGVMC---PSPDP 593
Query: 731 DANETLPLHL-YVK-----SYGKNIDSKLHVTLYNCSF-----GRSDCSLCRAANPDYRC 779
LP YV +G + +K ++ Y+C + C C ++ + C
Sbjct: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSR--WGC 651
Query: 780 AWCGGQSRCVYEALCNTTSECPPPVITRIQPETGP 814
WC Q C ++A C + P V + P P
Sbjct: 652 NWCVWQHLCTHKASC----DAGPMVASHQSPLVSP 682
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 988 bits (2553), Expect = 0.0
Identities = 555/1161 (47%), Positives = 740/1161 (63%), Gaps = 59/1161 (5%)
Query: 727 KLSHDANET-LPLHLYVKSYGK-NIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRCAWC 782
+LS++A + L + L+++ G+ +DS LHV LY+CS G DCS C+ A P Y C WC
Sbjct: 985 QLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVWC 1044
Query: 783 GGQS-RCVYEALCN----TTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQ- 836
G+ RCV C ++CP P+I ++P TGP+ GG R+TI GSNLG D+
Sbjct: 1045 EGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLG 1104
Query: 837 RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPK 896
++VAG C+ + Y VS+ +VC+ A+ G V+V G+ GR F +Q PK
Sbjct: 1105 MVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGR-GRGVSEHDFAYQDPK 1163
Query: 897 PLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT--KFGAQLQCVTGPQA 954
S+ P +GP+AGGT LT++G+ L TG ED+RV + PC + + QL+C T P+
Sbjct: 1164 VHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRP 1223
Query: 955 TRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQ-- 1012
T + + V +G + F Y +P + + P +SF SGGR I V GQ ++Q
Sbjct: 1224 TPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTP 1283
Query: 1013 RFAMVVIAEPLQSWQPPREAESLQPMTVVGT----------DYVFHNDTKVVFL-SPAVP 1061
R + V++ LQ Q + P T + N ++++ +PA+P
Sbjct: 1284 RIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVNSSQLITCRTPALP 1343
Query: 1062 EEPEAYNLTVLIEMDGHRALLRT-EAGAFEYVPDPTF-----ENFTGGVKKQVNKLIHAR 1115
PE + V +D T F Y DPT E+ T + + +
Sbjct: 1344 GLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVE 1403
Query: 1116 GTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIV 1175
G NL+ AM+ +E A +G C +KTLT LYCEPP QP P+ R+ +LPEF V
Sbjct: 1404 GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTV 1463
Query: 1176 KFGSREWVLGRVEYDTR-------VSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAE 1228
+ G+ + LG V+YD + V L + L+ + +++++ + Y RKS+QA
Sbjct: 1464 QMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLM----YRRKSKQAL 1519
Query: 1229 REYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLP 1288
R+Y+K++ QLE LE SVRDRCKKEFTDLM EM D T+D+ +GIP LDYK Y +R+FF
Sbjct: 1520 RDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFF-- 1577
Query: 1289 SKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKV 1348
G ++ + L +PE RRP VEQ L Q SNLLNSK FL FIHTLE+QR FSAR +
Sbjct: 1578 --PGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRA 1635
Query: 1349 YFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERMLSNWMSIC 1408
Y ASLLTVALHGKLEY+TDI+ TL +L+ QYV AKNPKLMLRR+ETVVE++L+NWMSIC
Sbjct: 1636 YVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKNPKLMLRRTETVVEKLLTNWMSIC 1694
Query: 1409 LYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVI 1468
LY +++DS GEPLY LF+ IKHQV+KGPVD+V KAKYTLND LL +DVEY PLT++ +
Sbjct: 1695 LYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNAL 1754
Query: 1469 VQ----DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQ 1524
+ +PVKVL+CDTISQ KEK++DQ+Y+G P + P P ++ +EWR G
Sbjct: 1755 LAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGH 1814
Query: 1525 -ILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLE 1583
ILSD D+TS+ +G W+R+NTL HY V DGAT+ L ++Q +PGER +LE
Sbjct: 1815 LILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLE 1874
Query: 1584 EEN----RVWHLVRPTDEVDEGKSKRGSVK--EKERTKAITEIYLTRLLSVKGTLQQFVD 1637
+ + R WHLV+P+DE + + +RGS++ E+ER KAI EIYLTRLLS+KGTLQ+FVD
Sbjct: 1875 DVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVD 1934
Query: 1638 NFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNILKNPH 1697
+ FQ +L+ VP AVKYFFD LDEQA++H I D+DTIHIWKTNSLPLRFW+NI+KNP
Sbjct: 1935 DLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQ 1994
Query: 1698 FIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYK 1757
F+FDV + +DA L VIAQTFMDACT +HKL RDSP NKLLYA++I YK+MVE YY
Sbjct: 1995 FVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYA 2054
Query: 1758 GIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQK 1817
IRQ V SDQ+MN+ LAE+S ++ L VALH+LY+Y KYYD+II ALEED AQK
Sbjct: 2055 DIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQK 2114
Query: 1818 MQLAFRLQQIAAALENKVTDL 1838
MQL +RLQQIAAA+ENKVTDL
Sbjct: 2115 MQLGYRLQQIAAAVENKVTDL 2135
Score = 417 bits (1072), Expect = e-116
Identities = 251/670 (37%), Positives = 350/670 (52%), Gaps = 41/670 (6%)
Query: 34 LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93
L HLA D SG +YLGA N L+QL LQLE V+TGP LD++ C PP+ +C +A+ T
Sbjct: 35 LQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT 94
Query: 94 DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153
+N NQLLL+ P LV CGS+ +G+C R L + L + G+ +VA+ND V+T
Sbjct: 95 NNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVST 152
Query: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNG---IIVSTRLLDRTDSREAFEAYTDHATYKAGY 210
VGLV+ G G+ +LFVG+G G ++TR L D + AF +Y + A G
Sbjct: 153 VGLVAQ-GLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQAAF-SYEETAKLAVGR 210
Query: 211 LSTNTQQFVAAFEDGPYVFFVFNQQDKHPARN--RTLLARMCREDPNYYSYLEMDLQCRD 268
LS + FV+AF G +F+F ++D R ++R+C D +YYSY+E+ L C
Sbjct: 211 LSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACE- 269
Query: 269 PDIHAAAFGTCLAASVAAP---GSGRVLYAVFSR---------DSRSSGGPGAG-LCLFP 315
+G AA+VA G VL+A FS S ++G GA LC FP
Sbjct: 270 ----GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFP 325
Query: 316 LDKVHAKMEANRNACYTGTREARD---IFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYP 372
LD+V R+ACYT A D + Y + + C + ++PCGS+H P P
Sbjct: 326 LDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSP 385
Query: 373 LGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSI 432
+ SR L T +L+ G+ LTAV V E+ HT+AFLG S G++ +VYL P Y +
Sbjct: 386 MASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQ 445
Query: 433 LVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVE 492
++ V RDL G LY MTQ + ++PV C + C C +DPYCGWCV+
Sbjct: 446 SIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLL 505
Query: 493 GRCTRKAECPRAEEASHWLWS--RSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEE 550
GRC+R++EC R + WLWS C+ V + P N+SR EV L+V LP L
Sbjct: 506 GRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPG 565
Query: 551 DELLCLFGESPPHPARVEGEAVICNS--PSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSY 608
+ C FGE PA + G V+C S PS PV P G D+V+V+++ LR G + +
Sbjct: 566 ESYSCHFGEH-QSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVE--LRFGAVVIAKT 622
Query: 609 QYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAH----MED 664
FYDC L + C +CVS+RW C W + H C + +V +H +
Sbjct: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSP 682
Query: 665 SCPQFLGPSP 674
P GPSP
Sbjct: 683 DPPARGGPSP 692
Score = 34.7 bits (78), Expect = 0.88
Identities = 48/215 (22%), Positives = 75/215 (34%), Gaps = 33/215 (15%)
Query: 620 SLEENLPCISCVSNRWT-CQWDLRYHECREASP-----NPEDGIVRAHMEDSCPQFLGPS 673
S ++L C SC+++R C W + C S PE + E C Q S
Sbjct: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
Query: 674 PLVIPMNHETDVNFQGKNLDTV---KGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSH 730
P I +V +L + + S H G + P + SG P
Sbjct: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFG----EHQSPALLTGSGVMC---PSPDP 593
Query: 731 DANETLPLHL-YVK-----SYGKNIDSKLHVTLYNCSF-----GRSDCSLCRAANPDYRC 779
LP YV +G + +K ++ Y+C + C C ++ + C
Sbjct: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSR--WGC 651
Query: 780 AWCGGQSRCVYEALCNTTSECPPPVITRIQPETGP 814
WC Q C ++A C + P V + P P
Sbjct: 652 NWCVWQHLCTHKASC----DAGPMVASHQSPLVSP 682
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 936 bits (2418), Expect = 0.0
Identities = 640/1938 (33%), Positives = 988/1938 (50%), Gaps = 194/1938 (10%)
Query: 9 TLLGLLGAGASLRPRKLDFFRSE--KELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66
TLL A S + R FR E + NHL VDE +G +YLGAVN +Y+L + L++
Sbjct: 24 TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVT 83
Query: 67 VATGPALDNKKCTPPIEASQCHEA-EMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125
TGP DN KC PP C+E T+NVN++LL+D RL+ CGSL++GIC L L
Sbjct: 84 HETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRL 143
Query: 126 SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVST 185
+ L E ++ +++ +E + G++ S D++ +G + +S+
Sbjct: 144 ED--LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISS 201
Query: 186 RLLDRTDSREAFEAYTDHATYKAGYLSTNTQQF----------VAAFEDGPYVFFVFNQQ 235
R L + + AY H + A + + F V F G +V+F+ Q
Sbjct: 202 RKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQP 261
Query: 236 DKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDIH----AAAF----GTC 279
+ T L R+C+ED + SY+E+ + C + AA+ G
Sbjct: 262 EMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAV 321
Query: 280 LAASVAAPGSGRVLYAVFSRDSRSS--GGPGAGLCLFPLDKVHAKMEANRNACYTGTREA 337
L ++ +L+ VFS+ + + LC+F L +++ +++ +CY G
Sbjct: 322 LGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTL 381
Query: 338 RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397
+ K DI C +F CG + + PLG D +RG V +T+V
Sbjct: 382 DLAWLKV--KDIPCSSALLTIDDNF-CGLD-MNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
Query: 398 AAENNHTVAFLGTSDGRILKVYLT-PDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAM 456
NH++AF+GT G++ K+ + P G + +Y+++ V V RD+ S D LY M
Sbjct: 438 YVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIM 497
Query: 457 TQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSK 516
++ ++ R+PV+ C Y +C +C S DP+CGWCV+ CTRK C R++E + S K
Sbjct: 498 SERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRFA-SEMK 556
Query: 517 SCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPHPARVEGEAVICNS 576
CV +T P N+S +Q V L + + C F + V G + C S
Sbjct: 557 QCVRLT-VHPNNISV-SQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYS 614
Query: 577 PSS--IP--VTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVS 632
P++ +P +T G HV V +QL + + S + FY+C S C+SCV
Sbjct: 615 PAAKEVPRIITENGDHHV-VQLQLKSKETGMTFASTSFVFYNCSVHNS------CLSCVE 667
Query: 633 NRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNL 692
+ + C W H C R + + CPQ L +++P+ + + KNL
Sbjct: 668 SPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPITLKAKNL 727
Query: 693 D-------------TVKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLH 739
++GS V + L+F ++ ++++ ++++ LP+
Sbjct: 728 PQPQSGQRGYECILNIQGSEQRVPA--LRFNSSSVQCQNTSYSYEGMEINN-----LPVE 780
Query: 740 LYVKSYGK-NIDSKLH--VTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALC-- 794
L V G NID+ V LY C R C LC A+PD+ C WC G +C C
Sbjct: 781 LTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPA 840
Query: 795 ---------NTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI-QRISVAGRN 844
S+C P IT I P TGP GG ++TI G NLG++ DI + VAG
Sbjct: 841 QESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVE 900
Query: 845 CSFQPERYSVSTRIVCVI-EAAETPFTGGVEVDVF----GKLGRSPPNVQFTFQQPKPLS 899
CS + Y + +IVC + EA + G VE+ V + RS + + F
Sbjct: 901 CSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARS--SQLYYFMTLTLSD 958
Query: 900 VEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFG-AQLQCVTGPQATRGQ 958
++P +GP +GGT +TI GT+L+ GS +V V PC + + + C T +
Sbjct: 959 LKPSRGPMSGGTQVTITGTNLNAGS--NVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLE 1016
Query: 959 MLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAM-- 1016
M + V + + + + F Y E+P + EP S SG I V G LIQ +
Sbjct: 1017 MKVSVQVDRAKI-HQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRA 1075
Query: 1017 -------VVIAEPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNL 1069
+ I E L + + +A P +G D+ + E PE +
Sbjct: 1076 KHGGKEHINICEVLNATEMTCQA----PALALGPDH-----------QSDLTERPEEFGF 1120
Query: 1070 TVLIEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNLNKAMTLQE 1127
+D ++LL F Y P+P FE F +G ++ + I +G NL +
Sbjct: 1121 I----LDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGN 1176
Query: 1128 AE----AFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWV 1183
+ VG + CT+ T+++ L CE P + K + + G E+
Sbjct: 1177 VKLNYTVLVGEKPCTV-TVSDVQLLCESPNLIGRHK-------------VMARVGGMEYS 1222
Query: 1184 LGRVEYDTRVSDVPLSL--ILPLVIVP--MVVVIAVSVYCYWRKSQQAEREYEKIKSQLE 1239
G V D PLSL I+ + + +++ I + Y RKS++++ ++++ Q++
Sbjct: 1223 PGMVYI---APDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMD 1279
Query: 1240 GLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMIT 1299
LE V CK+ F +L ++ + T+D+ AGIP LDY+TYT RV F G +D +
Sbjct: 1280 NLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLF----PGIEDHPVL 1335
Query: 1300 GKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALH 1359
L++P R+ VE+ L F+ L+N+K FL++FI TLE+QR FS R + ASL+ L
Sbjct: 1336 RDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQ 1395
Query: 1360 GKLEYYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSICLYQYLKDSAG 1418
KLEY TD++ L +L+++ + +KN PKL+LRR+E+V E+ML+NW + LY++LK+ AG
Sbjct: 1396 SKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAG 1455
Query: 1419 EPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDE-GVDAI 1477
EPL+ LF AIK Q+EKGP+DA+ +A+Y+L++ L+ ++Y L +S + D +
Sbjct: 1456 EPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEV 1515
Query: 1478 PVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQ-ILSDLDLTSQRE 1536
PVK+LNCDTI+QVKEKI+D +++ PCS P+ + LEWR GS A+ IL D D+T++ E
Sbjct: 1516 PVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIE 1575
Query: 1537 GRWKRVNTLMHYNVRDGATLIL-----------SKVGVSQQPEDSQQDL---PGERHAL- 1581
WKR+NTL HY V DG+ + L + VS+ +++ G +L
Sbjct: 1576 NDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLR 1635
Query: 1582 ---------LEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTL 1632
LE ++WHLV+ + D+ + RGS K ++EIYLTRLL+ KGTL
Sbjct: 1636 SRTPMITPDLESGVKMWHLVKNHEHGDQKEGDRGS-------KMVSEIYLTRLLATKGTL 1688
Query: 1633 QQFVDNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFW 1689
Q+FVD+ F+++ + H A+P A+KY FDFLDEQA+KH I D H WK+N LPLRFW
Sbjct: 1689 QKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFW 1748
Query: 1690 VNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYK 1749
VN++KNP F+FD+H + + DA LSV+AQTFMD+C+ +EH+L +DSPSNKLLYAK+I +YK
Sbjct: 1749 VNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYK 1808
Query: 1750 KMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINAL 1809
VE YY I +M +SDQDMN +LAE SR H + NT+ AL +++ Y KY +EI+ L
Sbjct: 1809 NWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPL 1868
Query: 1810 EEDPAAQKMQLAFRLQQI 1827
+ D K +LA++L+Q+
Sbjct: 1869 DHDDQCGKQKLAYKLEQV 1886
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 932 bits (2410), Expect = 0.0
Identities = 644/1948 (33%), Positives = 989/1948 (50%), Gaps = 208/1948 (10%)
Query: 5 LWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAKLQLE 64
+WA GL AG +P F S+ L HL V E +G VY+GAVN +Y+L L L
Sbjct: 1 MWAEA--GLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLL 58
Query: 65 QQVATGPALDNKKCTPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICALR 123
+ TGP DN+KC PP C H TDNVN+LLLLD RL+ CGS +GIC
Sbjct: 59 RAHVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFL 118
Query: 124 ALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPG-GDRVLFVGKGNGPHDNG-- 180
L + L E ++ +++S E + G++ + PG G LFVG P D
Sbjct: 119 RLDD--LFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGT---PIDGKSE 173
Query: 181 ---IIVSTRLLDRTDSREAFE-AYTDHATYKAGYLSTNTQQ--------FVAAFEDGPYV 228
+ S RL+ + + F Y D + ++T +V +F +V
Sbjct: 174 YFPTLSSRRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFV 233
Query: 229 FFVFNQQDKHPARN--------RTLLARMCREDPNYYSYLEMDLQCRDP--------DIH 272
+++ Q D + + R+C +DP +YSY+E + C D +
Sbjct: 234 YYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAY 293
Query: 273 AAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPG--AGLCLFPLDKVHAKMEANRNAC 330
+ G LA + VL+ VF++ ++ P + LCLF L + K++ +C
Sbjct: 294 LSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSC 353
Query: 331 YTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGL 390
Y G E + + ++ C F CG + PLG + GT +
Sbjct: 354 YRG--EGKLSLPWLLNKELGCINSPLQIDDDF-CGQD-FNQPLGGTVTIEGTPLFVDKDD 409
Query: 391 NLTAVTVAAENNHTVAFLGTSDGRILKVYL---TPDGTSS-EYDSILVEINKRVKRDLVL 446
LTAV TV F GT GRI K+ + P G + Y+S++ + + RDLVL
Sbjct: 410 GLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVL 469
Query: 447 SGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEE 506
S + LYAMT+ +V R+PV+ C+ Y +C C S+DP+CGWCV+ C+R+ C RA+E
Sbjct: 470 SPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADE 529
Query: 507 ASHWLWSRSKSCVAVTSAQPQNMS-RRAQGEVQLTVSPLPALSEEDELLCLFGESPPHPA 565
+ + CV +T QP+N+S +Q + L +P LS + C F + +
Sbjct: 530 PQRFA-ADLLQCVQLT-VQPRNVSVTMSQVPLVLQAWNVPDLSAG--VNCSFEDFTESES 585
Query: 566 RVEGEAVICNSPSS---IPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLE 622
+E + C SPS+ P+T D V + L + S + FY+C S
Sbjct: 586 VLEDGRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQS-- 643
Query: 623 ENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHE 682
C+SCV+ + C W H C + R ++ + CPQ L + + +P+
Sbjct: 644 ----CLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVV 699
Query: 683 TDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKL-------SHDANET 735
+ +NL + G + L F P + F + L S++ N+
Sbjct: 700 KPITLAARNLPQPQSGQR--GYECL-FHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDV 756
Query: 736 --LPLHLYVKSYGKNI---DSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVY 790
LP++L V G + + LY C R C LC A+P + C WC + RC
Sbjct: 757 SDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSL 816
Query: 791 EALC------------NTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQR- 837
C + +S C P I ++ PETGP GG R+TI G NLG++ D++
Sbjct: 817 RHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLG 876
Query: 838 ISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGK----LGRSPPNVQFTFQ 893
+ V CS Y + +IVC I A + V+V + R+ +FTF
Sbjct: 877 VRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFV 936
Query: 894 QPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT-KFGAQLQCVTGP 952
P V P +GP +GGT + I G+HL+ GS DV V++ G PC + + +++C+T P
Sbjct: 937 TPTFYRVSPSRGPLSGGTWIGIEGSHLNAGS--DVAVSVGGRPCSFSWRNSREIRCLTPP 994
Query: 953 QATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQ 1012
+ G + ++ + + NP + + Y E+P + +P S SGG + VTG + ++
Sbjct: 995 GQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVR 1054
Query: 1013 RFAMVVIAEP-LQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVP---------- 1061
EP +++ E E+ + +NDT +V +P+V
Sbjct: 1055 --------EPRIRAKYGGIEREN---------GCLVYNDTTMVCRAPSVANPVRSPPELG 1097
Query: 1062 EEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNL 1119
E P+ MD R+LL + +F Y PDP E TG ++ + + + +G NL
Sbjct: 1098 ERPDELGFV----MDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNL 1153
Query: 1120 ---NKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVK 1176
+ +G+ CT+ T++ET L CE P + K V+
Sbjct: 1154 LPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAPNLTGQHK-------------VTVR 1199
Query: 1177 FGSREWVLGRVEYDTRVSDVPLSLILPLVI-------VPMVVVIAVSVYCYWRKSQQAER 1229
G E+ G ++ SD L+L P ++ + ++V++AV + Y RKS+ A+R
Sbjct: 1200 AGGFEFSPGTLQV---YSDSLLTL--PAIVGIGGGGGLLLLVIVAVLI-AYKRKSRDADR 1253
Query: 1230 EYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPS 1289
++++ Q++ LE V CK+ F +L ++ + TND+ AGIP LDY+TY RV F
Sbjct: 1254 TLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLF--- 1310
Query: 1290 KDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVY 1349
G +D + ++++ + VE++L F LL K FL+ FI TLE QR FS R +
Sbjct: 1311 -PGIEDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGN 1365
Query: 1350 FASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSIC 1408
ASL+ AL G++EY T ++ L +L+E+ + +KN PKL+LRR+E+V E+ML+NW +
Sbjct: 1366 VASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFL 1425
Query: 1409 LYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVI 1468
LY++LK+ AGEPL+ L+ AIK Q+EKGP+DA+ +A+Y+L++ L+ ++Y LT++ +
Sbjct: 1426 LYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCV 1485
Query: 1469 -VQDEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQI-L 1526
++E +PVK L+CDT++Q KEK++D Y+G P S P+ + LEWR G A+I L
Sbjct: 1486 NPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIIL 1545
Query: 1527 SDLDLTSQREGRWKRVNTLMHYNVRDGATLIL------------------------SKVG 1562
D D+T++ + WKR+NTL HY V DG+++ L S +
Sbjct: 1546 QDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSLSRYESMLR 1605
Query: 1563 VSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYL 1622
+ P+ + P L E ++WHLV+ D +D+ + RGS K ++EIYL
Sbjct: 1606 TASSPDSLRSRTPMITPDL-ESGTKLWHLVKNHDHLDQREGDRGS-------KMVSEIYL 1657
Query: 1623 TRLLSVKGTLQQFVDNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIW 1679
TRLL+ KGTLQ+FVD+ F+++ + H A+P A+KY FDFLDEQA+KH I D D H W
Sbjct: 1658 TRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTW 1717
Query: 1680 KTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKL 1739
K+N LPLRFWVN++KNP F+FD+H + + DA LSV+AQTFMD+C+ +EHKL +DSPSNKL
Sbjct: 1718 KSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKL 1777
Query: 1740 LYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQ 1799
LYAK+I YK VE YY I +M +SDQDM+ +LAE SR H N++ ALH++Y Y
Sbjct: 1778 LYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYIT 1837
Query: 1800 KYYDEIINALEEDPAAQKMQLAFRLQQI 1827
KY DEI+ ALE+D A++ +L +L+Q+
Sbjct: 1838 KYKDEILAALEKDEQARRQRLRSKLEQV 1865
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 929 bits (2401), Expect = 0.0
Identities = 666/1952 (34%), Positives = 988/1952 (50%), Gaps = 187/1952 (9%)
Query: 5 LWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLD-AKLQL 63
L L LLG AGA R+ F S N+ A+D A+G VYL AVN LYQL A L L
Sbjct: 33 LLLLLLLGAARAGALEIQRR---FPSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSL 89
Query: 64 EQQVATGPALDNKKC-TPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICA 121
E + A GP D+ C P + + C H +TDN N++L LDP + +V CGS+++G C
Sbjct: 90 EAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQ 149
Query: 122 LRALSNISLRLFYEDGSGEKSF----------VASNDEGVATVGLV--SSTGPGGDRVL- 168
LR NIS + + VA+N +TVGLV + G GG R+L
Sbjct: 150 LRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLV 209
Query: 169 ---FVGKGNG-----------PHDNGIIVSTRLLD-RTDSREAFEAYTDHAT-----YKA 208
+ G G+ +N ++ R LD R D + F + + K
Sbjct: 210 GATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQ 269
Query: 209 GYLSTNTQQFVAAF---EDGP-----YVFFVFNQQDK---HPARNRTLLARMCREDPN-- 255
G + FV+AF D P Y + N + + ++ R+LLAR+C
Sbjct: 270 GAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGG 329
Query: 256 -----YYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGA- 309
SY+++ LQC A G + V+ + L+AVF R S A
Sbjct: 330 DAKKLTESYIQLGLQCAG----GAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAP 385
Query: 310 -GLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSF------ 362
LC F V A + A R AC+ A D+ D G P +
Sbjct: 386 AALCAFRFADVRAAIRAARTACFV--EPAPDVVAVL---DSVVQGTGPACERKLNIQLQP 440
Query: 363 ---PCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVY 419
CG+ HL +PL L+ T V + GL T+V VA+ NN+T FLGT +GR+LK+
Sbjct: 441 EQLDCGAAHLQHPLSILQPLKATPVFRAPGL--TSVAVASVNNYTAVFLGTVNGRLLKIN 498
Query: 420 LTPDGTSSEYDSILVEINKRVKRDLVLS-GDLGSLYAMTQDKVFRLPVQECLSYPTCTQC 478
L + V + V + D G LY MT ++ R+ V C + TC C
Sbjct: 499 LNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDC 558
Query: 479 RDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRS--KSCVAVTSAQPQNMSRRAQGE 536
+ D YCGWC +E RCT + +C + + W + C A+T + R+
Sbjct: 559 VGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPG 618
Query: 537 VQLTVS-PLPALSEEDELLCLFGESPPHPARVEGEA-----VICN--SPSSIPVTPPGQD 588
+ L +S LP+LS E+ C +G + ARV G A CN P PP QD
Sbjct: 619 MILQISGSLPSLSGM-EMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQD 677
Query: 589 HVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECR- 647
HV V + + + NI ++ YDC + + + C SC+S +W C W + H C
Sbjct: 678 HVTVEMSVRVNGRNIVKANFT--IYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVS 735
Query: 648 -----EASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHV 702
EASPNP CP+ L +P ++ N +G++L
Sbjct: 736 NQSRCEASPNPTS-------PQDCPRTLLSPLAPVPTGGSQNILVPLANTAFFQGAALEC 788
Query: 703 GSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSY-GKNIDSK--LHVTLYN 759
L + E V + ES + + ++ PL L +K + +DS + V +YN
Sbjct: 789 SFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYN 848
Query: 760 CSFGRSDCSLCRAANP-DYRCAWCGG-QSRCVYEALCNTTSECPPPVITRIQPETGPLGG 817
C+ G DCS C + C W G + R + + T CP P I I+P +GPL G
Sbjct: 849 CAMGSPDCSQCLGREDLGHLCMWSDGCRLRGPLQPMAGT---CPAPEIRAIEPLSGPLDG 905
Query: 818 GIRITILGSNLGVQAGDIQR-ISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVD 876
G +TI G NLG + D+ + + G C P+RY+VS IVCV A P +G V V+
Sbjct: 906 GTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVN 965
Query: 877 VFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVP 936
K G+S +F++ P S+EP GP+AGGT +TIHG L GS+ V V
Sbjct: 966 A-SKEGKSRD--RFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPC 1022
Query: 937 CKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFAS 996
++ + + C A + + V + + + F Y +NPV+ A P RS S
Sbjct: 1023 TELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVS 1082
Query: 997 GGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQP--MTVVGTDYVFHNDTKVV 1054
GGR+I V G+ F ++Q +M V + P + L +T + + V
Sbjct: 1083 GGRTITVAGERFHMVQNVSMAVH----HIGREPTLCKVLNSTLITCPSPGALSNASAPVD 1138
Query: 1055 FLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVKKQVNK---- 1110
F + A + V E+ R +Y+P+P F T +K +
Sbjct: 1139 FF---INGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFS--TAKREKWIKHHPGE 1193
Query: 1111 ----LIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDT 1166
+IH +L + E +G C ++ +++ ++C E
Sbjct: 1194 PLTLVIHKEQDSLG--LQSHEYRVKIGQVSCDIQIVSDRIIHCSVNE--------SLGAA 1243
Query: 1167 THNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQ 1226
LP ++ G+ + ++ + + +S+++ V++ ++ V+A+ V+C KS++
Sbjct: 1244 VGQLP-ITIQVGNFNQTIATLQLGGSETAIIVSIVICSVLL-LLSVVALFVFC--TKSRR 1299
Query: 1227 AEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEA-GIPVLDYKTYTDRVF 1285
AER ++K Q+E +E +R+ +K F +L +M D T +++ + GIP L+YK + R F
Sbjct: 1300 AERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTF 1359
Query: 1286 F------------LPSK----DGDKDVMIT----GKLDIPEPRRPVVEQALYQFSNLLNS 1325
F LPS+ G T G+ IPE RP +E+ + FS+LLN+
Sbjct: 1360 FPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNN 1419
Query: 1326 KSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKN 1385
K FLI F+H LE Q++F+ R + ASLLT+ALHGKLEYYT IM L ++L++ AKN
Sbjct: 1420 KHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDASA-AKN 1478
Query: 1386 PKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAK 1445
PKLMLRR+E+VVE+ML+NWMSIC+Y L+++ GEP + L AIK Q+ KG +DA+ KA+
Sbjct: 1479 PKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKAR 1538
Query: 1446 YTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCS 1505
YTLN+ LL +++E P ++V Q G+D++ V+ ++ DT++QVKEKI++ + P S
Sbjct: 1539 YTLNEEWLLRENIEAKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYS 1598
Query: 1506 CWPRPDSVVLEWRPGST-AQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKVGVS 1564
WPR + V LEW ST + IL DLD TS E K++NTL HY + +GA+L +S +
Sbjct: 1599 QWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKK 1658
Query: 1565 QQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTR 1624
+DL E++ +HLV PTDE+ E K S ++ R K + EIYLTR
Sbjct: 1659 DNTLGRVKDLDTEKY---------FHLVLPTDELAEPKK---SHRQSHRKKVLPEIYLTR 1706
Query: 1625 LLSVKGTLQQFVDNFFQSVLAPGHAVPP-AVKYFFDFLDEQAEKHNIQDEDTIHIWKTNS 1683
LLS KGTLQ+F+D+ F+++L+ PP AVKYFFDFL+EQAEK I D DT+HIWKTNS
Sbjct: 1707 LLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNS 1766
Query: 1684 LPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAK 1743
LPLRFWVNILKNP F+FD+ + +DA LSVIAQ F+DAC+ ++ +L +DSP+NKLLYAK
Sbjct: 1767 LPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAK 1826
Query: 1744 EISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYD 1803
EI Y+K+V+ YYK I+ M +S+Q+MN HLAE SR + + NT VA+ ++Y+Y ++Y
Sbjct: 1827 EIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRP 1886
Query: 1804 EIINALEEDPAAQKMQLAFRLQQIAAALENKV 1835
+I+ ALE +P A++ QL + +Q+ A +E+ +
Sbjct: 1887 QIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 924 bits (2387), Expect = 0.0
Identities = 633/1940 (32%), Positives = 990/1940 (51%), Gaps = 197/1940 (10%)
Query: 13 LLGAGASLRPRKLDFFRSEKE--LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATG 70
LL A+ P+ F ++ NHL V + +G VY+GA+N +Y+L L ++ TG
Sbjct: 27 LLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTG 86
Query: 71 PALDNKKCTPPIEASQCHEA-EMTDNVNQLLLLDPPRKRLVECGSLFKGICALRALSNIS 129
P DNK C PP+ C E +T+NVN+LL++D RL+ CGSL++G+C L L ++
Sbjct: 87 PEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLF 146
Query: 130 LRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKG-NGPHDNGIIVSTRLL 188
+ + + S +K S+ T+ V G D LF+G +G D +S+R L
Sbjct: 147 ILV---EPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKL 203
Query: 189 DRTDSREAFEAYTDHATYKAGYLSTNTQQ----------FVAAFEDGPYVFFVFNQQD-- 236
R A Y H+ + + + + ++ F G +V+F+ Q +
Sbjct: 204 PRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETP 263
Query: 237 KHPARNR-------TLLARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGTCLA 281
+ A N + + R+C++DP ++SY+ + C + + A G LA
Sbjct: 264 EGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLA 323
Query: 282 ASVAAPGSGRVLYAVFSRDSRSSGGP--GAGLCLFPLDKVHAKMEANRNACYTG--TREA 337
+ VL+A+FS+ + P + LC FP+ ++ +++ +CY G E
Sbjct: 324 QAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLEL 383
Query: 338 RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397
+ K D+QC AP CG + + PLG + G + +T+V
Sbjct: 384 NWLLGK----DVQCT-KAPVPIDDNFCGLD-INQPLGGSTPVEGLTLYTTSRDRMTSVAS 437
Query: 398 AAENNHTVAFLGTSDGRILKVYLT-PDGTSSEYDSILV-EINKRVKRDLVLSGDLGSLYA 455
N ++V F+GT G++ K+ P +Y+ + V + + RD+ S D LY
Sbjct: 438 YVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYV 497
Query: 456 MTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRS 515
M++ +V R+PV+ C Y TC +C S DP+CGWC + C+R+ +C +A E + + S S
Sbjct: 498 MSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRFAASIS 557
Query: 516 KSCVAVTSAQPQNMSRRAQGEV-QLTVSPLPALSEEDELLCLFGESPPHPARVEGEAVIC 574
+ CV++ + P ++S + L VS P LS + C FG +V G VIC
Sbjct: 558 Q-CVSL-AVHPSSISVSEHSRLLSLVVSDAPDLSAG--IACAFGNLTEVEGQVSGSQVIC 613
Query: 575 NSPS--SIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVS 632
SP +PV P QD + +QL + S ++ FY+C + C+SCV+
Sbjct: 614 ISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNC------SAHQLCLSCVN 667
Query: 633 NRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNL 692
+ + C W + C R ++ + CPQ + ++IP+ + + +NL
Sbjct: 668 SAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPITLKARNL 727
Query: 693 DTVKGSS------LHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANE--TLPLHLYVKS 744
+ L++ + + P S + + +D + L + V
Sbjct: 728 PQPQSGQRGYECVLNIQGAIHRV--PALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVW 785
Query: 745 YGKNI-----DSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNTTS- 798
G I D K+H LY C+ R C LC A+ + C WC G+ RC C + S
Sbjct: 786 NGNFIIDNPQDLKVH--LYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSS 843
Query: 799 ----------ECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI-QRISVAGRNCSF 847
+C P IT I +GP GG R+TI G NLG+ +I + VAG C+
Sbjct: 844 PWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTP 903
Query: 848 QPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLG---RSPPNVQFTFQQPKPLSVEPQQ 904
P Y ++ +IVC + A T G G+ + + Q+TF P LS+ P +
Sbjct: 904 LPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIR 963
Query: 905 GPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT-KFGAQLQCVTGPQATR-GQMLLE 962
GP++GGT +TI G +L GS V V L C+ + +++ CV+ P + G + +
Sbjct: 964 GPESGGTMVTITGHYLGAGSS--VAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVS 1021
Query: 963 VSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIAEP 1022
VS + V + + F Y ++P ++ EP S ASG + +TG F + VI EP
Sbjct: 1022 VSVDRAHVDS-NLQFEYIDDPRVQRIEPEWSIASGHTPLTITG--------FNLDVIQEP 1072
Query: 1023 LQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVP----------EEPEAYNLTVL 1072
+ ES+ VV T T + L+P++ E P+ +
Sbjct: 1073 -RIRVKFNGKESVNVCKVVNT-------TTLTCLAPSLTTDYRPGLDTVERPDEFGFV-- 1122
Query: 1073 IEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNLNKAMT---LQE 1127
+ ++LL F Y P+PTFE TG + ++ I +G NL +
Sbjct: 1123 --FNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLN 1180
Query: 1128 AEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRV 1187
+G C + T++ET L CEPP + K +V G + G V
Sbjct: 1181 YTVLIGETPCAV-TVSETQLLCEPPNLTGQHK-------------VMVHVGGMVFSPGSV 1226
Query: 1188 EYDTRVSDVPLSLILPLVIVP----MVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEE 1243
+SD L+L + I +++++ + + Y RKS++ + ++++ Q++ LE
Sbjct: 1227 SV---ISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLES 1283
Query: 1244 SVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLD 1303
V CK+ F +L ++ + T+D+ +GIP LDY+TY RV F G +D + +L+
Sbjct: 1284 RVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLF----PGIEDHPVLRELE 1339
Query: 1304 IPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLE 1363
+ + VE+AL F+ L+N+K FL+ FI TLE QR FS R + ASL+ L G+LE
Sbjct: 1340 VQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLE 1399
Query: 1364 YYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLY 1422
Y TD++ L +L+++ + KN PKL+LRR+E+V E+ML+NW + L+++LK+ AGEPL+
Sbjct: 1400 YATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLF 1459
Query: 1423 KLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQD-EGVDAIPVKV 1481
L+ AIK Q+EKGP+DA+ +A+Y+L++ L+ +EY L ++ + D E IPVKV
Sbjct: 1460 MLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKV 1519
Query: 1482 LNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQI-LSDLDLTSQREGRWK 1540
LNCDTI+QVKEKI+D VY+ P S PR + LEWR G A++ L D D+T++ EG WK
Sbjct: 1520 LNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWK 1579
Query: 1541 RVNTLMHYNVRDGATLIL----------------SKVGVSQQPEDSQQDLPGERHAL--- 1581
R+NTLMHY V D + + L S+ +S+ DS G +L
Sbjct: 1580 RLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRY--DSSFRYTGSPDSLRSR 1637
Query: 1582 -------LEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQ 1634
LE +VWHLV+ D D+ + RGS K ++EIYLTRLL+ KGTLQ+
Sbjct: 1638 APMITPDLESGVKVWHLVKNHDHGDQKEGDRGS-------KMVSEIYLTRLLATKGTLQK 1690
Query: 1635 FVDNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVN 1691
FVD+ F+++ + H A+P A+KY FDFLDEQA++H+I D D H WK+N LPLRFWVN
Sbjct: 1691 FVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVN 1750
Query: 1692 ILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKM 1751
++KNP F+FD+H + DA LSV+AQTFMD+C+ +EH+L +DSPSNKLLYAK+I +YK
Sbjct: 1751 VIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSW 1810
Query: 1752 VEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEE 1811
VE YY I ++ +SDQDMN +LAE SR H N L AL+++Y Y KY +E+I ALE+
Sbjct: 1811 VERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQ 1870
Query: 1812 DPAAQKMQLAFRLQQIAAAL 1831
D A++ +LA++++Q+ A+
Sbjct: 1871 DEQARRQRLAYKVEQLINAM 1890
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 893 bits (2307), Expect = 0.0
Identities = 628/1940 (32%), Positives = 957/1940 (49%), Gaps = 190/1940 (9%)
Query: 8 LTLLGLLGAGASLRPRKLD-FFRSEKELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66
L LL L G +L R F ++ L HLAV +G V++GAVN +++L L +
Sbjct: 6 LLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRA 65
Query: 67 VATGPALDNKKCTPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125
TGP DN +C PP C H DN+N+LLL+D +RLV CGS+++GIC L
Sbjct: 66 HVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRL 125
Query: 126 SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKG-NGPHDNGIIVS 184
+ L E ++ +++ E + G++ G G + LFVG +G + +S
Sbjct: 126 DD--LFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSK-LFVGTAVDGKSEYFPTLS 182
Query: 185 TR-LLDRTDSREAFE-AYTDHATYKAGYLSTNTQQFVAAFE--------DGPYVFFVFNQ 234
+R L+ DS + F Y D + ++T AF+ +V+F+ Q
Sbjct: 183 SRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQ 242
Query: 235 QDKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGT 278
D T + RMC D +YSY+E + C + H A G
Sbjct: 243 LDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGL 302
Query: 279 CLAASVAAPGSGRVLYAVFSRDSRSSGGPGAG--LCLFPLDKVHAKMEANRNACYTGTRE 336
LA ++ P VL+ +FS+ ++ P LCLF L ++A + +CY G E
Sbjct: 303 LLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRG--E 360
Query: 337 ARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVT 396
+ ++ C + +F CG L PLG + G +L + +V
Sbjct: 361 GTLALPWLLNKELPCINTPMQINGNF-CGLV-LNQPLGGLHVIEGLPLLADSTDGMASVA 418
Query: 397 VAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAM 456
H+V F+GT G + KV + + Y+++ V + RDL+ S D +Y +
Sbjct: 419 AYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLL 478
Query: 457 TQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSK 516
++ +V +LPV+ C Y +C C S DP+CGWCV+ RC R+ C A A H
Sbjct: 479 SEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGAS-APHGFAEELS 537
Query: 517 SCVAVTSAQPQNMSRRAQGEVQLTVS--PLPALSEEDELLCLFGESPPHPARVEGEAVI- 573
CV V +P N+S + G VQLTV+ +P LS G S A E EAV+
Sbjct: 538 KCVQVR-VRPNNVSVTSPG-VQLTVTLHNVPDLSA--------GVSCAFEAAAENEAVLL 587
Query: 574 ------CNSPSSIPVTPPGQDHVA---VTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEEN 624
C SPS + + H A V +QLL + + + FY+C S
Sbjct: 588 PSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQS---- 643
Query: 625 LPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETD 684
C+SCV + + C W H C R H + CP+ L L+IP+
Sbjct: 644 --CMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQP 701
Query: 685 VNFQGKNLDTVKGSSLH----VGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHL 740
+ + KNL + + V + P S + + S++ +E L
Sbjct: 702 LTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTEL 761
Query: 741 -----YVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCN 795
+ + + LY C R C LC A+P + C WC + RC C
Sbjct: 762 DFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCP 821
Query: 796 TT-----------SECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISVAGRN 844
+ C P IT+I P GP GG R+TI+G NLG+ + ++ + VAG
Sbjct: 822 APKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVG-LRVAGVR 880
Query: 845 CSFQPERYSVSTRIVCVIEAA--ETPFTGGVEVDVFGKLG--RSPPNVQFTFQQPKPLSV 900
C+ P Y + RIVC +E + +P G VE+ V R+ ++F P V
Sbjct: 881 CNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQV 940
Query: 901 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRG--Q 958
P +GP +GGT LTI G+ LD GS+ V VT+ C+ + A+ P +T G Q
Sbjct: 941 SPSRGPASGGTRLTISGSSLDAGSR--VTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQ 998
Query: 959 MLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVV 1018
+ ++ + + +PG+ +TY ++P + EP S +G +I V+G +Q
Sbjct: 999 APITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQE----- 1053
Query: 1019 IAEPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAV----------PEEPEAYN 1068
PR + + T V NDT ++ +P + E P+ +
Sbjct: 1054 ----------PRVRAKYRGIETTNTCQVI-NDTAMLCKAPGIFLGRPQPRAQGEHPDEFG 1102
Query: 1069 LTVLIEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNLNKAMTLQ 1126
+L + R+L R+ +F Y PDP+FE +G + + + +G NL A
Sbjct: 1103 F-LLDHVQTARSLNRS---SFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGS 1158
Query: 1127 EA---EAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWV 1183
+G + C++ T+++T L C+ P T P ++ G W
Sbjct: 1159 SRLNYTVLIGGQPCSL-TVSDTQLLCDSPS------------QTGRQPVMVLVGGLEFW- 1204
Query: 1184 LGRVEYDT-RVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLE 1242
LG + R +P + L +++ I + Y RK+Q A+R ++++ Q++ LE
Sbjct: 1205 LGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLE 1264
Query: 1243 ESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKL 1302
V CK+ F +L ++ + TN + E IP LDY+TY RV F G + + +L
Sbjct: 1265 SRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLF----PGIEAHPVLKEL 1320
Query: 1303 DIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKL 1362
D P P VE+AL F LL+S++F++ FIHTLE Q FS R + ASL VAL +L
Sbjct: 1321 DTP----PNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRL 1376
Query: 1363 EYYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPL 1421
+Y T ++ L +L+E+ + +KN PKL+LRR+E+V E+ML+NW + L+++LK+ AGEPL
Sbjct: 1377 DYATGLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPL 1436
Query: 1422 YKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIV-QDEGVDAIPVK 1480
+ L+ AIK Q+EKGP+DA+ +A+Y+L++ L+ ++Y LT+ + ++EG +PVK
Sbjct: 1437 FLLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVK 1496
Query: 1481 VLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGS-TAQILSDLDLTSQREGRW 1539
VLNCD+I+Q K+K++D VY+G P S P+ + + LEWR G T IL D D+T++ E W
Sbjct: 1497 VLNCDSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDW 1556
Query: 1540 KRVNTLMHYNVRDGATLILSKVGVSQQP-------------------EDSQQDLPGERHA 1580
KR+N+L HY V DG+ + L VS S D R
Sbjct: 1557 KRLNSLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAP 1616
Query: 1581 LL----EEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQFV 1636
++ E ++WHLV+ D D + RGS K ++EIYLTRLL+ KGTLQ+FV
Sbjct: 1617 MITPDQETGTKLWHLVKNHDHADHREGDRGS-------KMVSEIYLTRLLATKGTLQKFV 1669
Query: 1637 DNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNIL 1693
D+ F++V + H A+P A+KY FDFLDEQA++ I D D H WK+N LPLRFWVN++
Sbjct: 1670 DDLFETVFSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVI 1729
Query: 1694 KNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVE 1753
KNP F+FD+H + + DA LSV+AQTFMD+C+ +EH+L +DSPSNKLLYAK+I YK VE
Sbjct: 1730 KNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVE 1789
Query: 1754 DYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDP 1813
YY+ I +M +SDQDM+ +L E SR H + L AL++LY Y KY EI+ AL+ D
Sbjct: 1790 RYYRDIAKMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDA 1849
Query: 1814 AAQKMQLAFRLQQIAAALEN 1833
+ +K +L +L+QI + + +
Sbjct: 1850 SCRKHKLRQKLEQIISLVSS 1869
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 407 bits (1046), Expect = e-113
Identities = 284/851 (33%), Positives = 437/851 (51%), Gaps = 83/851 (9%)
Query: 990 PLRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQPMTVVGTDYVFHN 1049
P ++ SGG++I + G+ F +I ++I+ L+ + ++Y
Sbjct: 761 PATTWISGGQNITMMGRNFDVIDN---LIISHELKG-------------NINVSEYCVA- 803
Query: 1050 DTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFT--GGVKKQ 1107
T FL+P++ N+TV + + + G +Y DP F + V +
Sbjct: 804 -TYCGFLAPSLKSSKVRTNVTVKLRVQD----TYLDCGTLQYREDPRFTGYRVESEVDTE 858
Query: 1108 VNKLIHARGTNLNKAMTLQEAEAFVGAE---RCTMKTLTE----TDLYCEPPEVQPPPKR 1160
+ I N N + E F G C+ + +T T + C+ +
Sbjct: 859 LEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGI------ 912
Query: 1161 RQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVYCY 1220
+ ++ + VK G+ E VE ++ S ++LP+++V +VI +V
Sbjct: 913 KTASTIANSSKKVRVKLGNLELY---VEQESVPSTWYFLIVLPVLLV---IVIFAAVGVT 966
Query: 1221 WRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTY 1280
KS++ R K QLE LE +R + F +L ++ D + +P LDYK +
Sbjct: 967 RHKSKELSR---KQSQQLELLESELRKEIRDGFAELQMDKLDVVDSF--GTVPFLDYKHF 1021
Query: 1281 TDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQR 1340
R FF P G + D+ ++L L+ +KSFL+ IHTLE Q+
Sbjct: 1022 ALRTFF-PESGGFTHIFTE---DMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQK 1077
Query: 1341 EFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERM 1400
FS + + FAS LT+AL KL Y T I+ L +L+EQ PKLMLRR+E+VVE++
Sbjct: 1078 NFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQ-CSNMQPKLMLRRTESVVEKL 1136
Query: 1401 LSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEY 1460
L+NWMS+CL +L+++ GEP Y L + ++ KGPVD + KA YTLN+ LL E+
Sbjct: 1137 LTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEF 1196
Query: 1461 APLTVSVIVQ----DEGVDA---IPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSV 1513
+ + ++V+ + +E D I V VL+CDTI Q KEKI + + +
Sbjct: 1197 STVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEI 1256
Query: 1514 VLEWRPGSTAQILSDLDLTSQ-REGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQ 1572
LE + G+ + L D+D +S E ++NT+ HY + +G+T+ + K ++ D
Sbjct: 1257 GLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKK-IANFTSD--- 1312
Query: 1573 DLPGERHALLEEENRVWHLVRPTDEVDE---GKSKRGSVKEKERTKAITEIYLTRLLSVK 1629
+E + HL+ P E + GK RG K K + E+YLT+LLS K
Sbjct: 1313 ---------VEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFK-----VKEMYLTKLLSTK 1358
Query: 1630 GTLQQFVDNFFQSVLA-PGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRF 1688
+ ++ F+S+ + P P A+KYFFDFLD QAE I D D +HIWKTNSLPLRF
Sbjct: 1359 VAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRF 1418
Query: 1689 WVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTY 1748
WVNILKNP F+FD+ +D LSVIAQ FMDA + TE +L +++P+NKLLYAK+I TY
Sbjct: 1419 WVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTY 1478
Query: 1749 KKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINA 1808
K+ V+ YYK IR + +S +M L + S+ H + N VAL ++Y+Y KY+DEI+N
Sbjct: 1479 KEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNK 1538
Query: 1809 LEEDPAAQKMQ 1819
LE + ++ Q
Sbjct: 1539 LERERGLEEAQ 1549
Score = 73.6 bits (179), Expect = 2e-12
Identities = 45/133 (33%), Positives = 68/133 (51%), Gaps = 6/133 (4%)
Query: 391 NLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDL 450
+LT+V N TV FLGT DG++LKV L + TS+ ++ EI + L D
Sbjct: 375 DLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSN-CPEVIYEIKEETPVFYKLVPDP 433
Query: 451 GS---LYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEA 507
+Y +V R+ V C + +C++C + DP+CGWC RCT + +C +E
Sbjct: 434 VKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENL 493
Query: 508 SHWL--WSRSKSC 518
+WL S +K C
Sbjct: 494 ENWLDISSGAKKC 506
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 157 bits (397), Expect = 9e-38
Identities = 125/448 (27%), Positives = 204/448 (45%), Gaps = 38/448 (8%)
Query: 9 TLLGLLGAGASLRPRKLDFFRSE--KELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66
TLL A S + R FR E + NHL VDE +G +YLGAVN +Y+L + L++
Sbjct: 24 TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVT 83
Query: 67 VATGPALDNKKCTPPIEASQCHE-AEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125
TGP DN KC PP C+E T+NVN++LL+D RL+ CGSL++GIC L L
Sbjct: 84 HETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRL 143
Query: 126 SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVST 185
+ L E ++ +++ +E + G++ S D++ +G + +S+
Sbjct: 144 ED--LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISS 201
Query: 186 RLLDRTDSREAFEAYTDHATYKAGYLSTNTQQF----------VAAFEDGPYVFFVFNQQ 235
R L + + AY H + A + + F V F G +V+F+ Q
Sbjct: 202 RKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQP 261
Query: 236 DKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGTC 279
+ T L R+C+ED + SY+E+ + C + + + G
Sbjct: 262 EMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAV 321
Query: 280 LAASVAAPGSGRVLYAVFSRDS--RSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREA 337
L ++ +L+ VFS+ + + LC+F L +++ +++ +CY G
Sbjct: 322 LGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTL 381
Query: 338 RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397
+ K DI C +F CG + + PLG D +RG V +T+V
Sbjct: 382 DLAWLKV--KDIPCSSALLTIDDNF-CGLD-MNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
Query: 398 AAENNHTVAFLGTSDGRILKVYLT-PDG 424
NH++AF+GT G++ K + T P G
Sbjct: 438 YVYKNHSLAFVGTKSGKLKKSFGTGPQG 465
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 156 bits (395), Expect = 2e-37
Identities = 122/441 (27%), Positives = 201/441 (45%), Gaps = 37/441 (8%)
Query: 9 TLLGLLGAGASLRPRKLDFFRSE--KELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66
TLL A S + R FR E + NHL VDE +G +YLGAVN +Y+L + L++
Sbjct: 24 TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVT 83
Query: 67 VATGPALDNKKCTPPIEASQCHE-AEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125
TGP DN KC PP C+E T+NVN++LL+D RL+ CGSL++GIC L L
Sbjct: 84 HETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRL 143
Query: 126 SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVST 185
+ L E ++ +++ +E + G++ S D++ +G + +S+
Sbjct: 144 ED--LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISS 201
Query: 186 RLLDRTDSREAFEAYTDHATYKAGYLSTNTQQF----------VAAFEDGPYVFFVFNQQ 235
R L + + AY H + A + + F V F G +V+F+ Q
Sbjct: 202 RKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQP 261
Query: 236 DKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGTC 279
+ T L R+C+ED + SY+E+ + C + + + G
Sbjct: 262 EMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAV 321
Query: 280 LAASVAAPGSGRVLYAVFSRDS--RSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREA 337
L ++ +L+ VFS+ + + LC+F L +++ +++ +CY G
Sbjct: 322 LGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTL 381
Query: 338 RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397
+ K DI C +F CG + + PLG D +RG V +T+V
Sbjct: 382 DLAWLKV--KDIPCSSALLTIDDNF-CGLD-MNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
Query: 398 AAENNHTVAFLGTSDGRILKV 418
NH++AF+GT G++ K+
Sbjct: 438 YVYKNHSLAFVGTKSGKLKKM 458
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 111 bits (277), Expect = 7e-24
Identities = 138/521 (26%), Positives = 208/521 (39%), Gaps = 69/521 (13%)
Query: 40 DEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQL 99
D V++ N L+ L L+ Q +ATGPA D C D ++
Sbjct: 64 DRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPGDTDTKV 122
Query: 100 LLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSS 159
L+LDP LV CGS +G C L L + + F A ++ V+S
Sbjct: 123 LVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHL--AAPACLFSAHHNRPDDCPDCVAS 180
Query: 160 TGPGGDRVLFVGKGNGPH-----DNGIIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTN 214
P G RV V +G + V+ R+ S +A D + + G+++ +
Sbjct: 181 --PLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKA--DASGFAPGFVALS 236
Query: 215 TQ---------QFVAAFEDGPYVFFVFNQQDK---HPARNRTLLARMCREDPNYYSYLEM 262
++V +F G +V+F+ Q P+ T LAR+ +P Y E+
Sbjct: 237 VLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPELGDYREL 296
Query: 263 DLQCR---------DPD----------IHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRS 303
L CR P+ H+A G LA ++ VL+ VF +
Sbjct: 297 VLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFV--TGK 354
Query: 304 SGGPGAG----LCLFPLDKVHAKMEANRNAC-----YTGTREARDIFYKPFHGDIQCGGH 354
GGPG G +C FP+D + ++ C + G R D F P +
Sbjct: 355 DGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSFCP-----N 409
Query: 355 APGSSKSFPCGS-EHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDG 413
PG P S H P + S G + +TA+ V +N TVA +GT DG
Sbjct: 410 PPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAHMGTMDG 469
Query: 414 RILKVYLTPDGTSSEYDS--ILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQ--EC 469
RIL+V L Y S L + + V+RD+ GD L + D+VF++P+Q C
Sbjct: 470 RILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRLGD--HLLFASGDQVFQVPIQGPGC 527
Query: 470 LSYPTCTQC-RDSQDPYCGWCVVEGRCTRKAECPRAEEASH 509
+ TC +C R CGWC C ++ ECP + + H
Sbjct: 528 RHFLTCGRCLRAWHFMGCGWC--GNMCGQQKECPGSWQQDH 566
Score = 99.0 bits (245), Expect = 4e-20
Identities = 76/258 (29%), Positives = 105/258 (40%), Gaps = 47/258 (18%)
Query: 767 CSLCRAANPDYRCAWCGGQSRCVYEALCNTTSECP--------PPVITRIQPETGPLGGG 818
C C A C WCG +C ECP PP +T P +GPL G
Sbjct: 533 CGRCLRAWHFMGCGWCGN--------MCGQQKECPGSWQQDHCPPKLTEFHPHSGPLRGS 584
Query: 819 IRITILGSNL-----GVQAGDIQRISVAGRNCSFQPE---------RYSVSTRIVCVIEA 864
R+T+ GSN G+ +++V C P+ R C +E
Sbjct: 585 TRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEP 644
Query: 865 AETPFTGGVEVDVFGKLGRSPPNVQF-----------TFQQPKPLSVEPQQGPQAGGTTL 913
T G V + + PP F +F +P ++V+P GP+AGGT L
Sbjct: 645 LGTQAVGPTNVSL--TVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCL 702
Query: 914 TIHGTHLDTGSQEDVRVTLNGVPCKVTKFG-AQLQCVTGPQATRGQMLLEVSYGGSPVPN 972
T+ G L G+ V V NG C + + QL C T P AT + L + GG+ VP
Sbjct: 703 TLEGQSLSVGTSRAVLV--NGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQVPG 760
Query: 973 PGIFFTYRENPVLRAFEP 990
F YRE+PV+ + P
Sbjct: 761 SWT-FQYREDPVVLSISP 777
Score = 33.9 bits (76), Expect = 1.5
Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 33/170 (19%)
Query: 879 GKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTI--------------HGTHLDTGS 924
G+ P + Q PK P GP G T LT+ GTH T
Sbjct: 553 GQQKECPGSWQQDHCPPKLTEFHPHSGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVG 612
Query: 925 QEDVRVT------LNGVPCKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFT 978
Q R L VP K F + +C P T+ VS + +P PG F
Sbjct: 613 QSPCRPLPKDSSKLRPVPRK--DFVEEFECELEPLGTQAVGPTNVSLTVTNMP-PGKHFR 669
Query: 979 YRENPVLRAF----------EPLRSFASGGRSINVTGQGFSLIQRFAMVV 1018
VLR F +PL +GG + + GQ S+ A++V
Sbjct: 670 VDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQSLSVGTSRAVLV 719
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 96.3 bits (238), Expect = 2e-19
Identities = 132/579 (22%), Positives = 237/579 (40%), Gaps = 98/579 (16%)
Query: 24 KLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK-LQLEQQVATGPALDNKKCTPPI 82
+L F +E + ++ + E ++LGA N +Y L+ + LQ + TGP L++ C P
Sbjct: 42 QLPNFTAETPIQNVILHEHH--IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQ 99
Query: 83 EASQCHEAEMT-----DNVNQLLLLDPPRK-RLVECGSLFKGICALRALSN-------IS 129
+ S +A ++ DN+N L++D +L+ CGS+ +G C +
Sbjct: 100 DCSS--KANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSE 157
Query: 130 LRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGI------IV 183
+ + E S ++SS DR + GN + + +
Sbjct: 158 VHCIFSPQIEEPSQCPDCVVSALGAKVLSSVK---DRFINFFVGNTINSSYFPDHPLHSI 214
Query: 184 STRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPARN- 242
S R L T F + + + ++V AFE +++F+ Q++ A+
Sbjct: 215 SVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTF 274
Query: 243 RTLLARMCREDPNYYSYLEMDLQC------RDPDIHAAAFGTCLAASVAAPGS------- 289
T + R C + +SY+EM L+C + F AA V+ PG+
Sbjct: 275 HTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIG 334
Query: 290 ----GRVLYAVFSRDSRSSGGP--GAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYK 343
+L+ VF++ S P + +C FP+ V+ D F K
Sbjct: 335 ASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVN------------------DFFNK 376
Query: 344 PFH-GDIQCGGHAPGSSKSFPCGSEHLPYPLGS---RDGLRG--TAVLQRGGLN------ 391
+ +++C H G + L G RD R T LQR L
Sbjct: 377 IVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSE 436
Query: 392 --LTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGD 449
LT+++ + + T+A LGTS+GR ++V ++ G S+ + + L++ + V ++++
Sbjct: 437 VLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLD-SHPVSPEVIVEHT 495
Query: 450 L---GSLYAMTQDKVFRLPVQ--ECLSYPTCTQCRDSQDPY--CGWCVVEGRCTRKAECP 502
L G +T K+ ++P+ C + +C+QC S P+ CGWC +C
Sbjct: 496 LNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCL-SAPPFVQCGWC--------HDKCV 546
Query: 503 RAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLTV 541
R+EE W++ A+ P S +G +LT+
Sbjct: 547 RSEECLSGTWTQQICLPAIYKVFPN--SAPLEGGTRLTI 583
Score = 95.5 bits (236), Expect = 4e-19
Identities = 75/284 (26%), Positives = 131/284 (46%), Gaps = 24/284 (8%)
Query: 746 GKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNT---TSECPP 802
GK I +K+ + C +S CS C +A P +C WC +CV C + T +
Sbjct: 507 GKKI-TKIPLNGLGCRHFQS-CSQCLSAPPFVQCGWC--HDKCVRSEECLSGTWTQQICL 562
Query: 803 PVITRIQPETGPLGGGIRITILGSNLGVQAG---DIQ--RISVAGRNCSFQPERYSVSTR 857
P I ++ P + PL GG R+TI G + G + D++ R+ + +C+ +++T
Sbjct: 563 PAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTL 622
Query: 858 IVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHG 917
V A F + + + F++ P S+ P+ GP AGGT LT+ G
Sbjct: 623 KCTVGPAMNKHFNMSI---IISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTG 679
Query: 918 THLDTGSQEDVRVTLNGVPCKVTKF-GAQLQCVTGPQ--ATRGQMLLEVSYGGSPVPNPG 974
+L++G+ +++ G C + + L+C T Q +T + L++
Sbjct: 680 NYLNSGNSR--HISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETS--- 734
Query: 975 IFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVV 1018
F+YRE+P++ P +SF SGG +I G+ + + MV+
Sbjct: 735 -IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVI 777
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 96.3 bits (238), Expect = 2e-19
Identities = 132/579 (22%), Positives = 237/579 (40%), Gaps = 98/579 (16%)
Query: 24 KLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK-LQLEQQVATGPALDNKKCTPPI 82
+L F +E + ++ + E ++LGA N +Y L+ + LQ + TGP L++ C P
Sbjct: 42 QLPNFTAETPIQNVILHEHH--IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQ 99
Query: 83 EASQCHEAEMT-----DNVNQLLLLDPPRK-RLVECGSLFKGICALRALSN-------IS 129
+ S +A ++ DN+N L++D +L+ CGS+ +G C +
Sbjct: 100 DCSS--KANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSE 157
Query: 130 LRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGI------IV 183
+ + E S ++SS DR + GN + + +
Sbjct: 158 VHCIFSPQIEEPSQCPDCVVSALGAKVLSSVK---DRFINFFVGNTINSSYFPDHPLHSI 214
Query: 184 STRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPARN- 242
S R L T F + + + ++V AFE +++F+ Q++ A+
Sbjct: 215 SVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTF 274
Query: 243 RTLLARMCREDPNYYSYLEMDLQC------RDPDIHAAAFGTCLAASVAAPGS------- 289
T + R C + +SY+EM L+C + F AA V+ PG+
Sbjct: 275 HTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIG 334
Query: 290 ----GRVLYAVFSRDSRSSGGP--GAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYK 343
+L+ VF++ S P + +C FP+ V+ D F K
Sbjct: 335 ASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVN------------------DFFNK 376
Query: 344 PFH-GDIQCGGHAPGSSKSFPCGSEHLPYPLGS---RDGLRG--TAVLQRGGLN------ 391
+ +++C H G + L G RD R T LQR L
Sbjct: 377 IVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSE 436
Query: 392 --LTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGD 449
LT+++ + + T+A LGTS+GR ++V ++ G S+ + + L++ + V ++++
Sbjct: 437 VLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLD-SHPVSPEVIVEHT 495
Query: 450 L---GSLYAMTQDKVFRLPVQ--ECLSYPTCTQCRDSQDPY--CGWCVVEGRCTRKAECP 502
L G +T K+ ++P+ C + +C+QC S P+ CGWC +C
Sbjct: 496 LNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCL-SAPPFVQCGWC--------HDKCV 546
Query: 503 RAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLTV 541
R+EE W++ A+ P S +G +LT+
Sbjct: 547 RSEECLSGTWTQQICLPAIYKVFPN--SAPLEGGTRLTI 583
Score = 86.3 bits (212), Expect = 3e-16
Identities = 76/302 (25%), Positives = 132/302 (43%), Gaps = 42/302 (13%)
Query: 746 GKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNT---TSECPP 802
GK I +K+ + C +S CS C +A P +C WC +CV C + T +
Sbjct: 507 GKKI-TKIPLNGLGCRHFQS-CSQCLSAPPFVQCGWC--HDKCVRSEECLSGTWTQQICL 562
Query: 803 PVITRIQPETGPLGGGIRITILGSNLGVQAG---DIQ--RISVAGRNCSFQPERYSVSTR 857
P I ++ P + PL GG R+TI G + G + D++ R+ + +C+ +++T
Sbjct: 563 PAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTL 622
Query: 858 IVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHG 917
V A F + + + F++ P S+ P+ GP AGGT LT+ G
Sbjct: 623 KCTVGPAMNKHFNMSI---IISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTG 679
Query: 918 THLDTGSQEDVRVTLNGVPCKVTKF-GAQLQCVTGPQ--ATRGQMLLEVSYGGSPVPNPG 974
+L++G+ +++ G C + + L+C T Q +T + L++
Sbjct: 680 NYLNSGNSR--HISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETS--- 734
Query: 975 IFFTYRENPVLRAFEPLRS------------------FASGGRSINVTGQGFSLIQRFAM 1016
F+YRE+P++ P +S FASGG +I G+ + + M
Sbjct: 735 -IFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRM 793
Query: 1017 VV 1018
V+
Sbjct: 794 VI 795
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 74.7 bits (182), Expect = 8e-13
Identities = 92/321 (28%), Positives = 133/321 (41%), Gaps = 57/321 (17%)
Query: 218 FVAAFEDGPYVFFVFNQQDKHPAR----NRTLLARMCREDP---------NYYSYLEMDL 264
FV A E G +V+F F + AR + +AR+C+ D ++ S+L++ L
Sbjct: 226 FVQALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRL 285
Query: 265 QCRDPDIHAAAFGTCLAASVAAPGSGR-VLYAVFSRDSRSSGGPGAGLCLFPLDKVH--- 320
C P F A + GR L+ VF+ + S PG+ +C F LD++
Sbjct: 286 NCSVPGDSTFYFDVLQALTGPVNLHGRSALFGVFTTQTNSI--PGSAVCAFYLDEIERGF 343
Query: 321 -AKMEANRNACYTGTREARDIFYKPFHGDIQ-CGGHAPGSS------------KSFPCGS 366
K + R+ T + D P G GG A SS K+ P
Sbjct: 344 EGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLD 403
Query: 367 EHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAA--ENNHTVAFLGTSDGRILKVYLTPDG 424
+P P+ + L T+ R L AV A +N TV FLG++DG +LKV LTP G
Sbjct: 404 PAVP-PVTHQPLLTLTS---RALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKV-LTPGG 458
Query: 425 TSSEYDSILVE----------INKRVKRD------LVLSGDLGSLYAMTQDKVFRLPVQE 468
S + IL+E KR + L L + L+ + LP+
Sbjct: 459 RSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSR 518
Query: 469 CLSYPTCTQ-CRDSQDPYCGW 488
C + C + C SQDPYCGW
Sbjct: 519 CARHGACQRSCLASQDPYCGW 539
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 74.3 bits (181), Expect = 1e-12
Identities = 141/536 (26%), Positives = 197/536 (36%), Gaps = 98/536 (18%)
Query: 22 PRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKC--T 79
P +L +LN V + +++G + LY +++LE +T K +
Sbjct: 53 PGRLTPAEGADDLNIQRVLRVNRTLFIGDRDNLY----RVELEPPTSTELRYQRKLTWRS 108
Query: 80 PPIEASQCH-----EAEMTDNVNQLLLLDPPRKRLVECGS-LFKGICALRALSNISLRLF 133
P + + C E E + V LLL D L CGS F +CA N S+
Sbjct: 109 NPSDINVCRMKGKQEGECRNFVKVLLLRD--ESTLFVCGSNAFNPVCA-----NYSIDTL 161
Query: 134 YEDGSGEKSFV-ASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTD 192
G D A V L S D +LF ++ L DR
Sbjct: 162 QPVGDNISGMARCPYDPKHANVALFS------DGMLFTATVTDFLAIDAVIYRSLGDRPT 215
Query: 193 SREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVF-------NQQDKHPARNRTL 245
R D +K Y FV A E G +V+F F N +K
Sbjct: 216 LRTVKH---DSKWFKEPY-------FVHAVEWGSHVYFFFREIAMEFNYLEKVVVSR--- 262
Query: 246 LARMCRED---------PNYYSYLEMDLQCRDPDIHAAAFGTCLAAS-VAAPGSGRVLYA 295
+AR+C+ D + S+L+ L C P F A + V + G V+ A
Sbjct: 263 VARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVVLA 322
Query: 296 VFSRDSRSSGGPGAGLCLFPLDKVHAKMEAN----RNACYTGTREARDIFYKPFHGDIQC 351
VFS S S PG+ +C F L +V A E ++ T D +P G
Sbjct: 323 VFSTPSNSI--PGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAA 380
Query: 352 GGHAPGSS-----------KSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAE 400
G +S K+ P E +P LG + T L R L AV V A
Sbjct: 381 PGMQYNASSALPDDILNFVKTHPLMDEAVP-SLGHAPWILRT--LMRHQLTRVAVDVGAG 437
Query: 401 --NNHTVAFLGTSDGRILKVYLTPDGTSSEYD--SILVEINKRVKRD------------- 443
N TV FLG+ G +LK + P+ ++S S+ +E + + D
Sbjct: 438 PWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQR 497
Query: 444 ---LVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQ-CRDSQDPYCGWCVVEGRC 495
L L G L A V R+PV C Y C + C SQDPYCGW +G C
Sbjct: 498 LLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGW-APDGSC 552
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 69.7 bits (169), Expect = 2e-11
Identities = 110/511 (21%), Positives = 194/511 (37%), Gaps = 90/511 (17%)
Query: 23 RKLDFFRSE--KELNHLAVDEASGVVYLGAVNALYQLDAK---LQLEQQVATGPALDNKK 77
R L FF + ++ + L + +Y+GA A+ LD + + + + PA D KK
Sbjct: 51 RALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKK 110
Query: 78 CTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSL-FKGICALRALSNISLRLFYED 136
+ + +E + + + L+ + L CG+ F C L + L ED
Sbjct: 111 SECAFK-KKSNETQCFNFIRVLVSYNVTH--LYTCGTFAFSPACTFIELQDSYLLPISED 167
Query: 137 ----GSGEKSFVASNDEGVATVGLVSSTGP-----GGDRVLFVGKGNGPHDNGIIVSTRL 187
G G+ F ++ V + +G G + +L G+ P
Sbjct: 168 KVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQP----------- 216
Query: 188 LDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQ----DKHPARNR 243
+ +TD+ F + H FVAA V+F F + D +
Sbjct: 217 VLKTDN---FLRWLHHDA-----------SFVAAIPSTQVVYFFFEETASEFDFFERLHT 262
Query: 244 TLLARMCRED--------PNYYSYLEMDLQCRDPD---IHAAAFGTCLAA-SVAAPGSGR 291
+ +AR+C+ D + ++L+ L C P + L A S AP
Sbjct: 263 SRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADSPTAPH--- 319
Query: 292 VLYAVFSRDSRSSGGPGAGLCLFPLDKVHA---------KMEANRNACYTGTREARDIFY 342
+YAVF+ + G + +C F L + E +R Y G
Sbjct: 320 -IYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPET------ 372
Query: 343 KPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAE-- 400
P G G P S K+ +H + + GT +L + G+ T + V
Sbjct: 373 NPRPGSCSVG---PSSDKALTFMKDHFLMD----EQVVGTPLLVKSGVEYTRLAVETAQG 425
Query: 401 ---NNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMT 457
++H V +LGT+ G + K ++ D ++ + I + + R+L L+ G+++
Sbjct: 426 LDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGF 485
Query: 458 QDKVFRLPVQECLSYPTCTQCRDSQDPYCGW 488
V+R+P C Y +C C ++DP+C W
Sbjct: 486 SGGVWRVPRANCSVYESCVDCVLARDPHCAW 516
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 67.0 bits (162), Expect = 2e-10
Identities = 86/331 (25%), Positives = 133/331 (40%), Gaps = 61/331 (18%)
Query: 218 FVAAFEDGPYVFFVFNQ-QDKHPARNRTL---LARMCRED---------PNYYSYLEMDL 264
F+ A E G YV+F F + +H + + +AR+C+ D ++ S+L+ L
Sbjct: 223 FLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARL 282
Query: 265 QCRDPDIHAAAFGTCLAASVAAPGSG-RVLYAVFSRDSRSSGGPGAGLCLFPLDKVHA-- 321
C P F + + +G + VF+ S PG+ +C F +D +
Sbjct: 283 NCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSI--PGSAVCAFSMDDIEKVF 340
Query: 322 ----KMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPY------ 371
K + ++ +T E D KP G G A S E L +
Sbjct: 341 KGRFKEQKTPDSVWTAVPE--DKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPL 398
Query: 372 ------PLGSRDGLRGTAVLQRGGLNLTAVTV----AAENNHTVAFLGTSDGRILKVYLT 421
P+ T V R LTA++V N+TV F+G+ G +LKV L
Sbjct: 399 MDSAVPPIADEPWFTKTRVRYR----LTAISVDHSAGPYQNYTVIFVGSEAGMVLKV-LA 453
Query: 422 PDGTSSEYDSILVEI------------NKRVKR--DLVLSGDLGSLYAMTQDKVFRLPVQ 467
S DS+L+E N+ K+ L L D +LY + R+P+
Sbjct: 454 KTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLS 513
Query: 468 ECLSYPTCTQ-CRDSQDPYCGWCVVEGRCTR 497
C Y +C + C S+DPYCGW + +G C R
Sbjct: 514 RCERYGSCKKSCIASRDPYCGW-LSQGSCGR 543
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 67.0 bits (162), Expect = 2e-10
Identities = 86/331 (25%), Positives = 133/331 (40%), Gaps = 61/331 (18%)
Query: 218 FVAAFEDGPYVFFVFNQ-QDKHPARNRTL---LARMCRED---------PNYYSYLEMDL 264
F+ A E G YV+F F + +H + + +AR+C+ D ++ S+L+ L
Sbjct: 223 FLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARL 282
Query: 265 QCRDPDIHAAAFGTCLAASVAAPGSG-RVLYAVFSRDSRSSGGPGAGLCLFPLDKVHA-- 321
C P F + + +G + VF+ S PG+ +C F +D +
Sbjct: 283 NCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSI--PGSAVCAFSMDDIEKVF 340
Query: 322 ----KMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPY------ 371
K + ++ +T E D KP G G A S E L +
Sbjct: 341 KGRFKEQKTPDSVWTAVPE--DKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPL 398
Query: 372 ------PLGSRDGLRGTAVLQRGGLNLTAVTV----AAENNHTVAFLGTSDGRILKVYLT 421
P+ T V R LTA++V N+TV F+G+ G +LKV L
Sbjct: 399 MDSAVPPIADEPWFTKTRVRYR----LTAISVDHSAGPYQNYTVIFVGSEAGMVLKV-LA 453
Query: 422 PDGTSSEYDSILVEI------------NKRVKR--DLVLSGDLGSLYAMTQDKVFRLPVQ 467
S DS+L+E N+ K+ L L D +LY + R+P+
Sbjct: 454 KTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLS 513
Query: 468 ECLSYPTCTQ-CRDSQDPYCGWCVVEGRCTR 497
C Y +C + C S+DPYCGW + +G C R
Sbjct: 514 RCERYGSCKKSCIASRDPYCGW-LSQGSCGR 543
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 67.0 bits (162), Expect = 2e-10
Identities = 86/331 (25%), Positives = 133/331 (40%), Gaps = 61/331 (18%)
Query: 218 FVAAFEDGPYVFFVFNQ-QDKHPARNRTL---LARMCRED---------PNYYSYLEMDL 264
F+ A E G YV+F F + +H + + +AR+C+ D ++ S+L+ L
Sbjct: 223 FLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARL 282
Query: 265 QCRDPDIHAAAFGTCLAASVAAPGSG-RVLYAVFSRDSRSSGGPGAGLCLFPLDKVHA-- 321
C P F + + +G + VF+ S PG+ +C F +D +
Sbjct: 283 NCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSI--PGSAVCAFSMDDIEKVF 340
Query: 322 ----KMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPY------ 371
K + ++ +T E D KP G G A S E L +
Sbjct: 341 KGRFKEQKTPDSVWTAVPE--DKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPL 398
Query: 372 ------PLGSRDGLRGTAVLQRGGLNLTAVTV----AAENNHTVAFLGTSDGRILKVYLT 421
P+ T V R LTA++V N+TV F+G+ G +LKV L
Sbjct: 399 MDSAVPPIADEPWFTKTRVRYR----LTAISVDHSAGPYQNYTVIFVGSEAGMVLKV-LA 453
Query: 422 PDGTSSEYDSILVEI------------NKRVKR--DLVLSGDLGSLYAMTQDKVFRLPVQ 467
S DS+L+E N+ K+ L L D +LY + R+P+
Sbjct: 454 KTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLS 513
Query: 468 ECLSYPTCTQ-CRDSQDPYCGWCVVEGRCTR 497
C Y +C + C S+DPYCGW + +G C R
Sbjct: 514 RCERYGSCKKSCIASRDPYCGW-LSQGSCGR 543
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 67.0 bits (162), Expect = 2e-10
Identities = 86/331 (25%), Positives = 133/331 (40%), Gaps = 61/331 (18%)
Query: 218 FVAAFEDGPYVFFVFNQ-QDKHPARNRTL---LARMCRED---------PNYYSYLEMDL 264
F+ A E G YV+F F + +H + + +AR+C+ D ++ S+L+ L
Sbjct: 223 FLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARL 282
Query: 265 QCRDPDIHAAAFGTCLAASVAAPGSG-RVLYAVFSRDSRSSGGPGAGLCLFPLDKVHA-- 321
C P F + + +G + VF+ S PG+ +C F +D +
Sbjct: 283 NCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSI--PGSAVCAFSMDDIEKVF 340
Query: 322 ----KMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPY------ 371
K + ++ +T E D KP G G A S E L +
Sbjct: 341 KGRFKEQKTPDSVWTAVPE--DKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPL 398
Query: 372 ------PLGSRDGLRGTAVLQRGGLNLTAVTV----AAENNHTVAFLGTSDGRILKVYLT 421
P+ T V R LTA++V N+TV F+G+ G +LKV L
Sbjct: 399 MDSAVPPIADEPWFTKTRVRYR----LTAISVDHSAGPYQNYTVIFVGSEAGMVLKV-LA 453
Query: 422 PDGTSSEYDSILVEI------------NKRVKR--DLVLSGDLGSLYAMTQDKVFRLPVQ 467
S DS+L+E N+ K+ L L D +LY + R+P+
Sbjct: 454 KTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLS 513
Query: 468 ECLSYPTCTQ-CRDSQDPYCGWCVVEGRCTR 497
C Y +C + C S+DPYCGW + +G C R
Sbjct: 514 RCERYGSCKKSCIASRDPYCGW-LSQGSCGR 543
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 67.0 bits (162), Expect = 2e-10
Identities = 86/331 (25%), Positives = 133/331 (40%), Gaps = 61/331 (18%)
Query: 218 FVAAFEDGPYVFFVFNQ-QDKHPARNRTL---LARMCRED---------PNYYSYLEMDL 264
F+ A E G YV+F F + +H + + +AR+C+ D ++ S+L+ L
Sbjct: 223 FLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARL 282
Query: 265 QCRDPDIHAAAFGTCLAASVAAPGSG-RVLYAVFSRDSRSSGGPGAGLCLFPLDKVHA-- 321
C P F + + +G + VF+ S PG+ +C F +D +
Sbjct: 283 NCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSI--PGSAVCAFSMDDIEKVF 340
Query: 322 ----KMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPY------ 371
K + ++ +T E D KP G G A S E L +
Sbjct: 341 KGRFKEQKTPDSVWTAVPE--DKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPL 398
Query: 372 ------PLGSRDGLRGTAVLQRGGLNLTAVTV----AAENNHTVAFLGTSDGRILKVYLT 421
P+ T V R LTA++V N+TV F+G+ G +LKV L
Sbjct: 399 MDSAVPPIADEPWFTKTRVRYR----LTAISVDHSAGPYQNYTVIFVGSEAGMVLKV-LA 453
Query: 422 PDGTSSEYDSILVEI------------NKRVKR--DLVLSGDLGSLYAMTQDKVFRLPVQ 467
S DS+L+E N+ K+ L L D +LY + R+P+
Sbjct: 454 KTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLS 513
Query: 468 ECLSYPTCTQ-CRDSQDPYCGWCVVEGRCTR 497
C Y +C + C S+DPYCGW + +G C R
Sbjct: 514 RCERYGSCKKSCIASRDPYCGW-LSQGSCGR 543
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 63.9 bits (154), Expect = 1e-09
Identities = 113/499 (22%), Positives = 195/499 (39%), Gaps = 77/499 (15%)
Query: 37 LAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEA---EMT 93
L ++EAS + +GA AL+ L A + G + P S+CH+ T
Sbjct: 59 LLLEEASARLLVGARGALFSLSAN-----DIGDGAHKEIHWEASPEMQSKCHQKGKNNQT 113
Query: 94 DNVNQLLLLDPPRK-RLVECGS-LFKGICALRALSNISLRLFYEDGSGEKSF-VASNDEG 150
+ N + L L CG+ F+ +CA +L +E+G + + A G
Sbjct: 114 ECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTG 173
Query: 151 -VATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAG 209
+ GL ++T + + + PH RT+ E + + A +
Sbjct: 174 LIIDGGLYTATRYEFRSIPDIRRSRHPHSL----------RTE--ETPMHWLNDAEFVFS 221
Query: 210 YLSTNTQQFVAAFEDGPYVFFVFNQQDK--------HPARNRTLLARMCRED-------- 253
L ++ +D Y FF ++ + +AR+C+ D
Sbjct: 222 VLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQ 281
Query: 254 PNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRV-LYAVFSRDSRSSGGPGAGLC 312
+ S+L+ L C P ++ G C S+ A S R YA F+ ++ + +C
Sbjct: 282 KKWTSFLKARLICHIP-LYETLRGVC---SLDAETSSRTHFYAAFTLSTQWKTLEASAIC 337
Query: 313 LFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGS-------SKSFPCG 365
+ L ++ A G+R + + G + PGS S+ +
Sbjct: 338 RYDLAEIQAVFAGPYMEYQDGSRR-----WGRYEGGVP--EPRPGSCITDSLRSQGYN-S 389
Query: 366 SEHLP---------YPLGSRDGL--RGTAVLQRGGLNLT-----AVTVAAENNHTVAFLG 409
S+ LP +PL +R + RG +L + + T VT A + + FLG
Sbjct: 390 SQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLG 449
Query: 410 TSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQEC 469
T+DG I K + G ++ + ++ V+ +LV+S SLY V +LP+ C
Sbjct: 450 TADGWIHKAVVLGSGMHIIEETQVFRESQSVE-NLVISLLQHSLYVGAPSGVIQLPLSSC 508
Query: 470 LSYPTCTQCRDSQDPYCGW 488
Y +C C ++DPYCGW
Sbjct: 509 SRYRSCYDCILARDPYCGW 527
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 63.5 bits (153), Expect = 2e-09
Identities = 114/543 (20%), Positives = 216/543 (39%), Gaps = 101/543 (18%)
Query: 32 KELNHLAVDEASGVVYLGAVNALYQLD-AKLQLEQQVATGPALDNKKCTPPIEASQCHEA 90
++ + LA+D + + +GA N L++L A + L Q + D ++ ++ E
Sbjct: 124 RDFSQLALDPSGNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSC---QSKGKTEE 180
Query: 91 EMTDNVNQLLLLDPPRKRLVECGS-LFKGICALRALSNIS---------LRLFYEDGSGE 140
E + V L++ +++ CG+ F +C R + N+S R Y+
Sbjct: 181 ECQNYVRVLIVAG---RKVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNS 237
Query: 141 KSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAY 200
+ ++S E A + S G D ++ G+GP RT
Sbjct: 238 TAVISSQGELYAATVIDFS---GRDPAIYRSLGSGPPL-----------RT--------- 274
Query: 201 TDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPARNRTL---LARMCRED---- 253
A Y + +L N FVAA++ G + +F + RT+ +AR+C+ D
Sbjct: 275 ---AQYNSKWL--NEPNFVAAYDIGLFAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGR 329
Query: 254 ----PNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGA 309
+ ++++ L C P + L ++ P ++Y VF+ + S +
Sbjct: 330 FLLEDTWTTFMKARLNCSRPG-EVPFYYNELQSAFHLPEQD-LIYGVFTTNVNSIAA--S 385
Query: 310 GLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCG-----GHAPGSSKSFPC 364
+C F L + N Y A + + QCG G ++
Sbjct: 386 AVCAFNLSAISQAF--NGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQ 443
Query: 365 GSEHL-----------PYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDG 413
++ L P P ++D +R + ++ + A + + V ++GT G
Sbjct: 444 DAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLV-------VDLVQAKDTLYHVLYIGTESG 496
Query: 414 RILKVYLTPD----GTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQEC 469
ILK T G E +L + R L + +L+ +D V R+P++ C
Sbjct: 497 TILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERC 556
Query: 470 LSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHW-LWSRSKSCVAVTSAQPQN 528
+Y + C ++DPYCGW +G+ R C E++S+ LW+++ +T+ +N
Sbjct: 557 AAYRSQGACLGARDPYCGW---DGKQQR---CSTLEDSSNMSLWTQN-----ITACPVRN 605
Query: 529 MSR 531
++R
Sbjct: 606 VTR 608
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 62.0 bits (149), Expect = 5e-09
Identities = 120/542 (22%), Positives = 193/542 (35%), Gaps = 97/542 (17%)
Query: 6 WALTLLGLLGAGASLRPRKLDFFRSEKE----LNHLAVDEASGVVYLGAVNALYQLDAKL 61
WAL+ L G+ RP F R E E L + +Y+GA AL+ L + L
Sbjct: 42 WALSPRISLPLGSEERP----FLRFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNL 97
Query: 62 QL-----EQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDP-PRKRLVECGSL 115
Q++ G + K+ + S + D N + +L P L CG+
Sbjct: 98 SFLPGGEYQELLWGADAEKKQ-----QCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTA 152
Query: 116 -FKGICALRALSNISL------RLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVL 168
F +C + N +L + EDG G F D + LV D L
Sbjct: 153 AFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPF----DPNFKSTALVV------DGEL 202
Query: 169 FVGKGNGPHDNGIIVS-TRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPY 227
+ G + N +S ++ L T + + D A + Y+ + + +D Y
Sbjct: 203 YTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYIPESLGS-LQGDDDKIY 261
Query: 228 VFFVFNQQDKHPARNRTL--LARMCREDPN--------YYSYLEMDLQCRDPDIHAAAFG 277
FF Q+ N + +AR+C+ D + S+L+ L C PD F
Sbjct: 262 FFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPD-DGFPFN 320
Query: 278 TCLAASVAAPGS----GRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKM-----EANRN 328
+P + Y VF+ G+ +C+F + V E NR
Sbjct: 321 VLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRE 380
Query: 329 -----------------ACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPY 371
AC T + R I SS P +
Sbjct: 381 TQQWYTVTHPVPTPRPGACITNSARERKI----------------NSSLQLPDRVLNFLK 424
Query: 372 PLGSRDG-LRGTAVLQRGGLNLTAVTV----AAENNHTVAFLGTSDGRILKVYLTPDGTS 426
DG +R +L + V V + + V FLGT DGR+ K ++
Sbjct: 425 DHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKA-VSVGPRV 483
Query: 427 SEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYC 486
+ + + + + ++L+L G LYA + V ++P+ C Y +C C ++DPYC
Sbjct: 484 HIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYC 543
Query: 487 GW 488
W
Sbjct: 544 AW 545
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 62.0 bits (149), Expect = 5e-09
Identities = 120/542 (22%), Positives = 193/542 (35%), Gaps = 97/542 (17%)
Query: 6 WALTLLGLLGAGASLRPRKLDFFRSEKE----LNHLAVDEASGVVYLGAVNALYQLDAKL 61
WAL+ L G+ RP F R E E L + +Y+GA AL+ L + L
Sbjct: 42 WALSPRISLPLGSEERP----FLRFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNL 97
Query: 62 QL-----EQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDP-PRKRLVECGSL 115
Q++ G + K+ + S + D N + +L P L CG+
Sbjct: 98 SFLPGGEYQELLWGADAEKKQ-----QCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTA 152
Query: 116 -FKGICALRALSNISL------RLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVL 168
F +C + N +L + EDG G F D + LV D L
Sbjct: 153 AFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPF----DPNFKSTALVV------DGEL 202
Query: 169 FVGKGNGPHDNGIIVS-TRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPY 227
+ G + N +S ++ L T + + D A + Y+ + + +D Y
Sbjct: 203 YTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYIPESLGS-LQGDDDKIY 261
Query: 228 VFFVFNQQDKHPARNRTL--LARMCREDPN--------YYSYLEMDLQCRDPDIHAAAFG 277
FF Q+ N + +AR+C+ D + S+L+ L C PD F
Sbjct: 262 FFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPD-DGFPFN 320
Query: 278 TCLAASVAAPGS----GRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKM-----EANRN 328
+P + Y VF+ G+ +C+F + V E NR
Sbjct: 321 VLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRE 380
Query: 329 -----------------ACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPY 371
AC T + R I SS P +
Sbjct: 381 TQQWYTVTHPVPTPRPGACITNSARERKI----------------NSSLQLPDRVLNFLK 424
Query: 372 PLGSRDG-LRGTAVLQRGGLNLTAVTV----AAENNHTVAFLGTSDGRILKVYLTPDGTS 426
DG +R +L + V V + + V FLGT DGR+ K ++
Sbjct: 425 DHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKA-VSVGPRV 483
Query: 427 SEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYC 486
+ + + + + ++L+L G LYA + V ++P+ C Y +C C ++DPYC
Sbjct: 484 HIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYC 543
Query: 487 GW 488
W
Sbjct: 544 AW 545
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 61.6 bits (148), Expect = 7e-09
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 384 VLQRGGLNLT-----AVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINK 438
+L + G N T VT +TV F+GT DG +LK G L ++
Sbjct: 412 LLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSL--GPWVHLIEELQLFDQ 469
Query: 439 RVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRC 495
R LVLS L+A ++ ++ +LPV +C+ Y +C C ++DPYC W V RC
Sbjct: 470 EPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRC 526
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 58.5 bits (140), Expect = 6e-08
Identities = 75/317 (23%), Positives = 127/317 (40%), Gaps = 54/317 (17%)
Query: 223 EDGPYVFFVFNQQDKHPARNRTLLARM---CREDPN--------YYSYLEMDLQCRDPDI 271
+D Y FF + PA R ++R+ CR D + ++L+ L C P +
Sbjct: 239 DDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGV 298
Query: 272 HAAA-FGTCLAASVAAPGSGR--VLYAVFSRDSRSSGGPGAGLCLFPLDKV--------- 319
F + + R +LYAVFS + SS G+ +C++ ++ V
Sbjct: 299 EGDTHFDQLQDVFLLSSRDHRTPLLYAVFS--TSSSIFQGSAVCVYSMNDVRRAFLGPFA 356
Query: 320 HAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPG---SSKSFPCG----SEHLPYP 372
H + ++ Y G P+ C G S+K FP + + P
Sbjct: 357 HKEGPMHQWVSYQGR--------VPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLM 408
Query: 373 LGSRDGLRGTAVLQRGGLNLTAVTVAAEN------NHTVAFLGTSDGRILKVYLTPDGTS 426
S G + + G N T +AA+ ++ V F+GT G +LKV P G+
Sbjct: 409 YNSVLPTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSR 468
Query: 427 SEYDSILVE-----INKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSY-PTCTQCRD 480
+ +L+E + + +S LY ++ V ++ + C ++ CT+C
Sbjct: 469 PSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCL 528
Query: 481 SQDPYCGWCVVEGRCTR 497
++DPYC W V CTR
Sbjct: 529 ARDPYCAWDGV--ACTR 543
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,610,428
Number of Sequences: 37866
Number of extensions: 3725478
Number of successful extensions: 9382
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 8885
Number of HSP's gapped (non-prelim): 178
length of query: 1838
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1721
effective length of database: 13,817,196
effective search space: 23779394316
effective search space used: 23779394316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.