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Search of human proteins with 149274655
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo
sapiens]
(1194 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sa... 2431 0.0
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 443 e-124
gi|229094128 active breakpoint cluster region-related protein i... 135 2e-31
gi|38679957 active breakpoint cluster region-related protein is... 135 2e-31
gi|38679954 active breakpoint cluster region-related protein is... 135 2e-31
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 133 1e-30
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 120 1e-26
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 103 1e-21
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 103 1e-21
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 103 1e-21
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 103 1e-21
gi|188497642 ARHGAP15 [Homo sapiens] 102 3e-21
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 101 4e-21
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 100 8e-21
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 97 9e-20
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 97 1e-19
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 96 2e-19
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 96 2e-19
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 95 5e-19
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 95 5e-19
gi|156119615 myosin IXA [Homo sapiens] 92 2e-18
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens] 89 2e-17
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 88 6e-17
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 88 6e-17
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 88 6e-17
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 87 1e-16
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 87 1e-16
gi|91208437 GEM interacting protein [Homo sapiens] 86 3e-16
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 85 4e-16
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 85 4e-16
>gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo
sapiens]
Length = 1194
Score = 2431 bits (6301), Expect = 0.0
Identities = 1194/1194 (100%), Positives = 1194/1194 (100%)
Query: 1 MHDLPPDSGARRGGRGLADHSFPAGARAPGQPPSRGAAYRRACPRDGERGGGGRPRQQVS 60
MHDLPPDSGARRGGRGLADHSFPAGARAPGQPPSRGAAYRRACPRDGERGGGGRPRQQVS
Sbjct: 1 MHDLPPDSGARRGGRGLADHSFPAGARAPGQPPSRGAAYRRACPRDGERGGGGRPRQQVS 60
Query: 61 PPRSPQREPRGGQLRTPRMRPSCSRSLESLRVGAKPPPFQRWPSDSWIRCGAHRDWDEPP 120
PPRSPQREPRGGQLRTPRMRPSCSRSLESLRVGAKPPPFQRWPSDSWIRCGAHRDWDEPP
Sbjct: 61 PPRSPQREPRGGQLRTPRMRPSCSRSLESLRVGAKPPPFQRWPSDSWIRCGAHRDWDEPP 120
Query: 121 PRGGRMDGWSGDRARAAAPTGLQPPGCKDHGCSSGSPFRDPAGSSVIRSGKGDRQEGPSF 180
PRGGRMDGWSGDRARAAAPTGLQPPGCKDHGCSSGSPFRDPAGSSVIRSGKGDRQEGPSF
Sbjct: 121 PRGGRMDGWSGDRARAAAPTGLQPPGCKDHGCSSGSPFRDPAGSSVIRSGKGDRQEGPSF 180
Query: 181 LRPPAVTVKKLQKWMYKGRLLSLGMKGRARGTAPKVTGTQAASPNVGALKVRENRVLSVP 240
LRPPAVTVKKLQKWMYKGRLLSLGMKGRARGTAPKVTGTQAASPNVGALKVRENRVLSVP
Sbjct: 181 LRPPAVTVKKLQKWMYKGRLLSLGMKGRARGTAPKVTGTQAASPNVGALKVRENRVLSVP 240
Query: 241 PDQRITLTDLFENAYGSSMKGRELEELKDNIEFRGHKPLNSITVSKKRNWLYQSTLRPLN 300
PDQRITLTDLFENAYGSSMKGRELEELKDNIEFRGHKPLNSITVSKKRNWLYQSTLRPLN
Sbjct: 241 PDQRITLTDLFENAYGSSMKGRELEELKDNIEFRGHKPLNSITVSKKRNWLYQSTLRPLN 300
Query: 301 LEEENKKCQDRSHLSISPVSLPKHQLSQSFLKSSKEYCTYVVCNATNSSLSKNCALDFNE 360
LEEENKKCQDRSHLSISPVSLPKHQLSQSFLKSSKEYCTYVVCNATNSSLSKNCALDFNE
Sbjct: 301 LEEENKKCQDRSHLSISPVSLPKHQLSQSFLKSSKEYCTYVVCNATNSSLSKNCALDFNE 360
Query: 361 ENDADDEGEIWYNPIPEDDDLGISSALSFGEADSAVLKLPAVNLSMLSGSDLMKAERHTE 420
ENDADDEGEIWYNPIPEDDDLGISSALSFGEADSAVLKLPAVNLSMLSGSDLMKAERHTE
Sbjct: 361 ENDADDEGEIWYNPIPEDDDLGISSALSFGEADSAVLKLPAVNLSMLSGSDLMKAERHTE 420
Query: 421 DSLCSSEHAGDIQTTRSNGMNPIHPAHSTEFVQQYKQKLGHKTQEGIMVEDSPMLKSPFA 480
DSLCSSEHAGDIQTTRSNGMNPIHPAHSTEFVQQYKQKLGHKTQEGIMVEDSPMLKSPFA
Sbjct: 421 DSLCSSEHAGDIQTTRSNGMNPIHPAHSTEFVQQYKQKLGHKTQEGIMVEDSPMLKSPFA 480
Query: 481 GSGILAATNSTELGIMEPSSPNPSPVKKGSSINWSLPDKIKSPRTVRKLSMKMKKLPEFS 540
GSGILAATNSTELGIMEPSSPNPSPVKKGSSINWSLPDKIKSPRTVRKLSMKMKKLPEFS
Sbjct: 481 GSGILAATNSTELGIMEPSSPNPSPVKKGSSINWSLPDKIKSPRTVRKLSMKMKKLPEFS 540
Query: 541 RKLSVKGTLNYINSPDNTPSLSKYNCREVHHTDILPSGNTTTAAKRNVISRYHLDTSVSS 600
RKLSVKGTLNYINSPDNTPSLSKYNCREVHHTDILPSGNTTTAAKRNVISRYHLDTSVSS
Sbjct: 541 RKLSVKGTLNYINSPDNTPSLSKYNCREVHHTDILPSGNTTTAAKRNVISRYHLDTSVSS 600
Query: 601 QQSYQKKNSMSSKYSCKGGYLSDGDSPELTTKASKHGSENKFGKGKEIISNSCSKNEIDI 660
QQSYQKKNSMSSKYSCKGGYLSDGDSPELTTKASKHGSENKFGKGKEIISNSCSKNEIDI
Sbjct: 601 QQSYQKKNSMSSKYSCKGGYLSDGDSPELTTKASKHGSENKFGKGKEIISNSCSKNEIDI 660
Query: 661 DAFRHYSFSDQPKCSQYISGLMSVHFYGAEDLKPPRIDSKDVFCAIQVDSVNKARTALLT 720
DAFRHYSFSDQPKCSQYISGLMSVHFYGAEDLKPPRIDSKDVFCAIQVDSVNKARTALLT
Sbjct: 661 DAFRHYSFSDQPKCSQYISGLMSVHFYGAEDLKPPRIDSKDVFCAIQVDSVNKARTALLT 720
Query: 721 CRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHGTVVLPTLFRVTKTHQLAV 780
CRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHGTVVLPTLFRVTKTHQLAV
Sbjct: 721 CRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHGTVVLPTLFRVTKTHQLAV 780
Query: 781 KLEPRGLIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIM 840
KLEPRGLIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIM
Sbjct: 781 KLEPRGLIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIM 840
Query: 841 EIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLREL 900
EIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLREL
Sbjct: 841 EIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLREL 900
Query: 901 PSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDH 960
PSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDH
Sbjct: 901 PSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDH 960
Query: 961 LKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVL 1020
LKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVL
Sbjct: 961 LKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVL 1020
Query: 1021 HYLLQLWPVQRLTVKKSTDNLFPEQKSSLNYLRQKKERPHMLNLSGTDSSGVLRPRQNRL 1080
HYLLQLWPVQRLTVKKSTDNLFPEQKSSLNYLRQKKERPHMLNLSGTDSSGVLRPRQNRL
Sbjct: 1021 HYLLQLWPVQRLTVKKSTDNLFPEQKSSLNYLRQKKERPHMLNLSGTDSSGVLRPRQNRL 1080
Query: 1081 DSPLSNRYAGDWSSCGENYFLNTKENLNDVDYDDVPSEDRKIGENYSKMDGPEVMIEQPI 1140
DSPLSNRYAGDWSSCGENYFLNTKENLNDVDYDDVPSEDRKIGENYSKMDGPEVMIEQPI
Sbjct: 1081 DSPLSNRYAGDWSSCGENYFLNTKENLNDVDYDDVPSEDRKIGENYSKMDGPEVMIEQPI 1140
Query: 1141 PMSKECTFQTYLTMQTVESTVDRKNNLKDLQESIDTLIGNLERELNKNKLNMSF 1194
PMSKECTFQTYLTMQTVESTVDRKNNLKDLQESIDTLIGNLERELNKNKLNMSF
Sbjct: 1141 PMSKECTFQTYLTMQTVESTVDRKNNLKDLQESIDTLIGNLERELNKNKLNMSF 1194
>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens]
Length = 735
Score = 443 bits (1139), Expect = e-124
Identities = 297/703 (42%), Positives = 388/703 (55%), Gaps = 111/703 (15%)
Query: 497 EPSSPNP-SPVKKGSSINWSLP-------DKIKSPRTVRKLSMKMKKLPEFSRKLSVKGT 548
EP P P S +G + + P + KSP R+LS+KMKKLPE R+LS++G
Sbjct: 126 EPPGPQPGSAESEGLAPQGAAPASPPTKASRTKSPGPARRLSIKMKKLPELRRRLSLRG- 184
Query: 549 LNYINSPDNTPSLSKYNCREVHHTDILPSGNTTTAAKRNVISRYHLDTSVSSQQSYQKKN 608
P + R P+G+ VISRYHLD+SV
Sbjct: 185 ----------PRAGRERERAA------PAGS--------VISRYHLDSSVGGPGPAAGPG 220
Query: 609 SMSSKYSCKGGYLSDGDSPELTTKASKHGSENKFGKGKEIISNSCSKNEIDIDAFRHYSF 668
S + GYLSDGDSPE S FR Y
Sbjct: 221 GTRSP---RAGYLSDGDSPERPAGPPSPTS------------------------FRPYEV 253
Query: 669 SDQPKCSQY-ISGLMSVHFYGAEDLKP-PRIDSKDVFCAIQVDSVNKARTALLTCRTTFL 726
+ + G +S+H YG L+P P +D+ C +QVD +ART L FL
Sbjct: 254 GPAARAPPAALWGRLSLHLYGLGGLRPAPGATPRDLCCLLQVDGEARARTGPLRGGPDFL 313
Query: 727 DMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHGTVVLPTLFRVTKTHQLAVKLEPRG 786
+DHTF++E+E A+ L+ +V +W+P R++R C GTV+LPT+FR + QLAV+LEP+G
Sbjct: 314 RLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTVFRGCQAQQLAVRLEPQG 373
Query: 787 LIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRG 846
L+Y K+TL EQ E EP +FG+ + +VE+E VPL+IQKC+ +IE+RG
Sbjct: 374 LLYAKLTLSEQQE-----APATAEPRVFGLPLPLLVERERPPGQVPLIIQKCVGQIERRG 428
Query: 847 CQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLIT 906
+VVGLYRLCGSAAVKKELR+AFERDS AV L E+ YPDINVITG+LKDYLRELP+PLIT
Sbjct: 429 LRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYPDINVITGILKDYLRELPTPLIT 488
Query: 907 KQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVAS 966
+ LY+ VL+AMA+ P P ++ T LL CLP++E+ATL +LLDHL+LV+S
Sbjct: 489 QPLYKVVLEAMARDP-------PNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRLVSS 541
Query: 967 YHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026
+H N+MT QNLAVCFGPVLL RQ P+ R + LASA+DFK HIEVLHYLLQ
Sbjct: 542 FHAYNRMTPQNLAVCFGPVLLPARQAPT--RPRARSSGPGLASAVDFKHHIEVLHYLLQS 599
Query: 1027 WPVQRLTVKKSTDNLFPEQKSSL-NYLRQKKERPHMLNLSGTDSSGVLRPR-QNRLDSPL 1084
WP RL P Q + YLR K++ P L+L D V RPR + +SP
Sbjct: 600 WPDPRL----------PRQSPDVAPYLRPKRQPP--LHLPLADPEVVTRPRGRGGPESPP 647
Query: 1085 SNRYAGDWSSCGENYFLNTKENLNDVDYDDVPSEDRKIGENYSKMDGPEVMIEQPIPMSK 1144
SNRYAGDWS CG ++ ++ L+ DYD V D + D E + E +
Sbjct: 648 SNRYAGDWSVCGRDFLPCGRDFLSGPDYDHVTGSDSE--------DEDEEVGEPRVTGDF 699
Query: 1145 ECTFQTYLTMQTVESTVDRKNNLKDLQESIDTLIGNLERELNK 1187
E F ++ + NLKD D LI +LEREL+K
Sbjct: 700 EDDF---------DAPFNPHLNLKD----FDALILDLERELSK 729
Score = 31.6 bits (70), Expect = 4.7
Identities = 11/12 (91%), Positives = 12/12 (100%)
Query: 368 GEIWYNPIPEDD 379
GEIWYNPIPE+D
Sbjct: 108 GEIWYNPIPEED 119
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 135 bits (340), Expect = 2e-31
Identities = 111/372 (29%), Positives = 177/372 (47%), Gaps = 36/372 (9%)
Query: 680 GLMSVHFYGAEDLKPPRIDSKDVFCAIQVDS----VNKARTALLTCRTTFLDMDHTFNIE 735
G + V + A+ K S +++C ++VDS V+KA+T + T D F IE
Sbjct: 458 GFLHVIVHSAKGFK----QSANLYCTLEVDSFGYFVSKAKTRVFR-DTAEPKWDEEFEIE 512
Query: 736 IENAQHLKLVVFS--WEPTPRK-------NRVCCHGTVVLPTLFRVTKTHQLAVKLEPRG 786
+E +Q L+++ + ++ T +++ G + L TK V +E G
Sbjct: 513 LEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDV-IEMNG 571
Query: 787 LIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRG 846
+ + SL ++ +FGV I V ++E VP ++++C+ E+EKRG
Sbjct: 572 IKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERS--KVPYIVRQCVEEVEKRG 629
Query: 847 CQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLIT 906
+ VG+YR+ G A + L+ F+ ++K + L + DIN I G LK Y RELP PL+T
Sbjct: 630 IEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLT 688
Query: 907 KQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVAS 966
+LY A ++ +A S N + LL LP+ T LL+HLK VA
Sbjct: 689 DRLYPAFMEGIALSDPAAKEN----------CMMHLLRSLPDPNLITFLFLLEHLKRVAE 738
Query: 967 YHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026
+NKM+ NLA FGP LL PS ++ S + D ++VL Y LQ
Sbjct: 739 KEPINKMSLHNLATVFGPTLL----RPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 794
Query: 1027 WPVQRLTVKKST 1038
P+ +K++T
Sbjct: 795 PPISFAELKRNT 806
>gi|38679957 active breakpoint cluster region-related protein isoform
a [Homo sapiens]
Length = 859
Score = 135 bits (340), Expect = 2e-31
Identities = 111/372 (29%), Positives = 177/372 (47%), Gaps = 36/372 (9%)
Query: 680 GLMSVHFYGAEDLKPPRIDSKDVFCAIQVDS----VNKARTALLTCRTTFLDMDHTFNIE 735
G + V + A+ K S +++C ++VDS V+KA+T + T D F IE
Sbjct: 504 GFLHVIVHSAKGFK----QSANLYCTLEVDSFGYFVSKAKTRVFR-DTAEPKWDEEFEIE 558
Query: 736 IENAQHLKLVVFS--WEPTPRK-------NRVCCHGTVVLPTLFRVTKTHQLAVKLEPRG 786
+E +Q L+++ + ++ T +++ G + L TK V +E G
Sbjct: 559 LEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDV-IEMNG 617
Query: 787 LIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRG 846
+ + SL ++ +FGV I V ++E VP ++++C+ E+EKRG
Sbjct: 618 IKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERS--KVPYIVRQCVEEVEKRG 675
Query: 847 CQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLIT 906
+ VG+YR+ G A + L+ F+ ++K + L + DIN I G LK Y RELP PL+T
Sbjct: 676 IEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLT 734
Query: 907 KQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVAS 966
+LY A ++ +A S N + LL LP+ T LL+HLK VA
Sbjct: 735 DRLYPAFMEGIALSDPAAKEN----------CMMHLLRSLPDPNLITFLFLLEHLKRVAE 784
Query: 967 YHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026
+NKM+ NLA FGP LL PS ++ S + D ++VL Y LQ
Sbjct: 785 KEPINKMSLHNLATVFGPTLL----RPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 840
Query: 1027 WPVQRLTVKKST 1038
P+ +K++T
Sbjct: 841 PPISFAELKRNT 852
>gi|38679954 active breakpoint cluster region-related protein isoform
b [Homo sapiens]
Length = 822
Score = 135 bits (340), Expect = 2e-31
Identities = 111/372 (29%), Positives = 177/372 (47%), Gaps = 36/372 (9%)
Query: 680 GLMSVHFYGAEDLKPPRIDSKDVFCAIQVDS----VNKARTALLTCRTTFLDMDHTFNIE 735
G + V + A+ K S +++C ++VDS V+KA+T + T D F IE
Sbjct: 467 GFLHVIVHSAKGFK----QSANLYCTLEVDSFGYFVSKAKTRVFR-DTAEPKWDEEFEIE 521
Query: 736 IENAQHLKLVVFS--WEPTPRK-------NRVCCHGTVVLPTLFRVTKTHQLAVKLEPRG 786
+E +Q L+++ + ++ T +++ G + L TK V +E G
Sbjct: 522 LEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDV-IEMNG 580
Query: 787 LIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRG 846
+ + SL ++ +FGV I V ++E VP ++++C+ E+EKRG
Sbjct: 581 IKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERS--KVPYIVRQCVEEVEKRG 638
Query: 847 CQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLIT 906
+ VG+YR+ G A + L+ F+ ++K + L + DIN I G LK Y RELP PL+T
Sbjct: 639 IEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLT 697
Query: 907 KQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVAS 966
+LY A ++ +A S N + LL LP+ T LL+HLK VA
Sbjct: 698 DRLYPAFMEGIALSDPAAKEN----------CMMHLLRSLPDPNLITFLFLLEHLKRVAE 747
Query: 967 YHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026
+NKM+ NLA FGP LL PS ++ S + D ++VL Y LQ
Sbjct: 748 KEPINKMSLHNLATVFGPTLL----RPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 803
Query: 1027 WPVQRLTVKKST 1038
P+ +K++T
Sbjct: 804 PPISFAELKRNT 815
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 133 bits (334), Expect = 1e-30
Identities = 117/405 (28%), Positives = 195/405 (48%), Gaps = 57/405 (14%)
Query: 647 EIISNSCSKNEIDIDAFRHYSFSDQPKCSQYISGLMSVHFYGAEDLKPPRIDSKDVFCAI 706
++++NSC K + + D Y G ++V + A K S +++C +
Sbjct: 880 QMLTNSCVKLQTVHSIPLTINKEDDESPGLY--GFLNVIVHSATGFK----QSSNLYCTL 933
Query: 707 QVDS----VNKARTALLTCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHG 762
+VDS VNKA+T + T + + F IE+E +Q L+++ + C+
Sbjct: 934 EVDSFGYFVNKAKTRVYR-DTAEPNWNEEFEIELEGSQTLRILCYEK----------CYN 982
Query: 763 TVVLPTLFRVTKTHQLA---VKLEPRGL--------------IYVKVTL-MEQWENSLHG 804
+P + + V+L+P+ L I VK+++ E SL
Sbjct: 983 KTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKR 1042
Query: 805 LDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKE 864
+ ++ +FGV I V ++E VP ++++C+ EIE+RG + VG+YR+ G A +
Sbjct: 1043 MPSRKQTGVFGVKIAVVTKRERS--KVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQA 1100
Query: 865 LREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKM 924
L+ AF+ ++K V + ++ D+N I G LK Y RELP PL T + Y + +A S +
Sbjct: 1101 LKAAFDVNNKDVSVMMSEM-DVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSD-PV 1158
Query: 925 SSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGP 984
+ C ++LL LPE T LLDHLK VA VNKM+ NLA FGP
Sbjct: 1159 AKESC---------MLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGP 1209
Query: 985 VLLSQRQEPS---THNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026
LL ++ S + ++ T ++ + +L+ ++VL Y LQL
Sbjct: 1210 TLLRPSEKESKLPANPSQPITMTD--SWSLEVMSQVQVLLYFLQL 1252
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 120 bits (300), Expect = 1e-26
Identities = 112/389 (28%), Positives = 180/389 (46%), Gaps = 69/389 (17%)
Query: 647 EIISNSCSKNEIDIDAFRHYSFSDQPKCSQYISGLMSVHFYGAEDLKPPRIDSKDVFCAI 706
++++NSC K + + D Y G ++V + A K S +++C +
Sbjct: 880 QMLTNSCVKLQTVHSIPLTINKEDDESPGLY--GFLNVIVHSATGFK----QSSNLYCTL 933
Query: 707 QVDS----VNKARTALL--TCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCC 760
+VDS VNKA+T + T + ++D L W+ T +
Sbjct: 934 EVDSFGYFVNKAKTRVYRDTAEPNWNELDPQ-----------ALQDRDWQRTV----IAM 978
Query: 761 HGTVVLPTLFRVTKTHQLAVKLEPRGLIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQK 820
+G V +L+VK R E SL + ++ +FGV I
Sbjct: 979 NGIEV-----------KLSVKFNSR-------------EFSLKRMPSRKQTGVFGVKIAV 1014
Query: 821 VVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCE 880
V ++E VP ++++C+ EIE+RG + VG+YR+ G A + L+ AF+ ++K V +
Sbjct: 1015 VTKRERS--KVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMM 1072
Query: 881 NQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTV 940
++ D+N I G LK Y RELP PL T + Y + +A S ++ C +
Sbjct: 1073 SEM-DVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSD-PVAKESC---------ML 1121
Query: 941 DLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPS---THN 997
+LL LPE T LLDHLK VA VNKM+ NLA FGP LL ++ S +
Sbjct: 1122 NLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANP 1181
Query: 998 NRVFTDSEELASALDFKKHIEVLHYLLQL 1026
++ T ++ + +L+ ++VL Y LQL
Sbjct: 1182 SQPITMTD--SWSLEVMSQVQVLLYFLQL 1208
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 103 bits (256), Expect = 1e-21
Identities = 62/182 (34%), Positives = 94/182 (51%), Gaps = 12/182 (6%)
Query: 806 DINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKEL 865
D+ + ++ D+ +V+ N P+++ CI EIE RG + GLYR+ G +++
Sbjct: 267 DLKRIKKVYCCDLTTLVKAHNT--QRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDV 324
Query: 866 REAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMS 925
+ AF+RD + + N YPDIN+ITG LK Y R+LP P+IT Y +DA S
Sbjct: 325 KMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKIS----- 379
Query: 926 SNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPV 985
N + ++L LP TL+ L+ HLK V + N M +NL + FGP
Sbjct: 380 -----NADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPT 434
Query: 986 LL 987
L+
Sbjct: 435 LM 436
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 103 bits (256), Expect = 1e-21
Identities = 62/182 (34%), Positives = 94/182 (51%), Gaps = 12/182 (6%)
Query: 806 DINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKEL 865
D+ + ++ D+ +V+ N P+++ CI EIE RG + GLYR+ G +++
Sbjct: 131 DLKRIKKVYCCDLTTLVKAHNT--QRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDV 188
Query: 866 REAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMS 925
+ AF+RD + + N YPDIN+ITG LK Y R+LP P+IT Y +DA S
Sbjct: 189 KMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKIS----- 243
Query: 926 SNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPV 985
N + ++L LP TL+ L+ HLK V + N M +NL + FGP
Sbjct: 244 -----NADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPT 298
Query: 986 LL 987
L+
Sbjct: 299 LM 300
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 103 bits (256), Expect = 1e-21
Identities = 59/157 (37%), Positives = 87/157 (55%), Gaps = 12/157 (7%)
Query: 832 PLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITG 891
P+++ CI EIE RG GLYR+ G + + ++++ AF+RD + + N Y DIN+ITG
Sbjct: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341
Query: 892 VLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTV-DLLDCLPEIE 950
LK Y R+LP PLIT Y +++ AK DP + T+ + L LP
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIES-AKI----------MDPDEQLETLHEALKLLPPAH 390
Query: 951 KATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLL 987
TL+ L+ HLK V + + N M +NL + FGP L+
Sbjct: 391 CETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLM 427
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 103 bits (256), Expect = 1e-21
Identities = 59/157 (37%), Positives = 87/157 (55%), Gaps = 12/157 (7%)
Query: 832 PLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITG 891
P+++ CI EIE RG GLYR+ G + + ++++ AF+RD + + N Y DIN+ITG
Sbjct: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315
Query: 892 VLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTV-DLLDCLPEIE 950
LK Y R+LP PLIT Y +++ AK DP + T+ + L LP
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIES-AKI----------MDPDEQLETLHEALKLLPPAH 364
Query: 951 KATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLL 987
TL+ L+ HLK V + + N M +NL + FGP L+
Sbjct: 365 CETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLM 401
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 102 bits (253), Expect = 3e-21
Identities = 61/180 (33%), Positives = 98/180 (54%), Gaps = 13/180 (7%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
IFG + KV E+EN VP +++CI +EKRG V G+YR+ G+ A ++LR ++
Sbjct: 278 IFGSHLHKVCERENS--TVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQE 335
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCEND 932
K + L ++Q+ DI+V+TG LK + RELP PL +E ++A+ K +++
Sbjct: 336 EK-LNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKK----------QDN 384
Query: 933 PGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQE 992
+ L+ LP + T+K+L HL + + N M+ Q+L + FGP LL E
Sbjct: 385 NTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENE 444
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 101 bits (252), Expect = 4e-21
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 14/180 (7%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG ++ + ++EN VP ++ CI +E+ G + G+YR+ G+ AV ++LR A D
Sbjct: 653 VFGSNLANLCQRENG--TVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD 710
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCEND 932
K + L ++++ DI+VITG LK + RELP PL T + ++A+ + P + +
Sbjct: 711 EK-LDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAA----- 764
Query: 933 PGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQE 992
DL+ LP+ + T+++L HL+ V E N+MT Q++A+ FGP LL +E
Sbjct: 765 ------VKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKE 818
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 100 bits (249), Expect = 8e-21
Identities = 59/182 (32%), Positives = 93/182 (51%), Gaps = 12/182 (6%)
Query: 831 VPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVIT 890
+PL++ C +E+RG + G+YR+ G+ A ++E + + + ++++ D+NVI+
Sbjct: 1161 IPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVIS 1220
Query: 891 GVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVD-LLDCLPEI 949
+LK + R+LP PL T Y ++A K DP D T+ L+ LPE
Sbjct: 1221 SLLKSFFRKLPEPLFTNDKYADFIEANRK-----------EDPLDRLKTLKRLIHDLPEH 1269
Query: 950 EKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELAS 1009
TLK L HLK VA E NKM +NLA+ FGP L+ ++ TH D ++
Sbjct: 1270 HYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVE 1329
Query: 1010 AL 1011
L
Sbjct: 1330 TL 1331
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 97.1 bits (240), Expect = 9e-20
Identities = 60/185 (32%), Positives = 94/185 (50%), Gaps = 11/185 (5%)
Query: 811 PIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFE 870
P FGV +++ + VPL++ C +E RG + G+YR+ G+ AV L+E
Sbjct: 806 PRAFGVRLEEC-QPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLN 864
Query: 871 RDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCE 930
R + L + ++ D+NVI+ +LK + R+LP PL T Y ++A N E
Sbjct: 865 RGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEA----------NRIE 914
Query: 931 NDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQR 990
+ + L+ LP TLK L+ HLK +A + E NKM +NLA+ FGP L+
Sbjct: 915 DARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTS 974
Query: 991 QEPST 995
++ T
Sbjct: 975 EDNMT 979
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 96.7 bits (239), Expect = 1e-19
Identities = 70/224 (31%), Positives = 109/224 (48%), Gaps = 26/224 (11%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG D G VP +++KC+ EIE+R + G+YR+ G ++L +AFE
Sbjct: 758 LFGQDFSHAARSAPDG--VPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENG 815
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVL-----DAMAKSPLKMSSN 927
+ V L + DI+ VLK YLR+LP PLI+ +LY ++ A++ K +S
Sbjct: 816 KELVELSQASPHDIS---NVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASR 872
Query: 928 GCENDPGDSKYTV-------DLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAV 980
G ++ V +LL LP +A+L+ LL HL+ + + NKMT NL +
Sbjct: 873 GRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGI 932
Query: 981 CFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLL 1024
FGP LL R +T L+S +D+ V+ L+
Sbjct: 933 VFGPTLLRPRPTEAT---------VSLSSLVDYPHQARVIETLI 967
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 96.3 bits (238), Expect = 2e-19
Identities = 59/183 (32%), Positives = 96/183 (52%), Gaps = 13/183 (7%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG + + E+E VP +Q+CI +E RG + GLYR+ G+ A ++LR + D
Sbjct: 326 VFGCALAALCERERS--RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD 383
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCEND 932
+ + L + ++ D++VITG LK + RELP PL + + A+ ++
Sbjct: 384 ER-LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIK----------LQDQ 432
Query: 933 PGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQE 992
S+ DL+ LP TL+ML HL V + E N+M+ Q++A+ FGP LL E
Sbjct: 433 ARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVE 492
Query: 993 PST 995
++
Sbjct: 493 ETS 495
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 96.3 bits (238), Expect = 2e-19
Identities = 59/183 (32%), Positives = 96/183 (52%), Gaps = 13/183 (7%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG + + E+E VP +Q+CI +E RG + GLYR+ G+ A ++LR + D
Sbjct: 353 VFGCALAALCERERS--RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD 410
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCEND 932
+ + L + ++ D++VITG LK + RELP PL + + A+ ++
Sbjct: 411 ER-LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIK----------LQDQ 459
Query: 933 PGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQE 992
S+ DL+ LP TL+ML HL V + E N+M+ Q++A+ FGP LL E
Sbjct: 460 ARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVE 519
Query: 993 PST 995
++
Sbjct: 520 ETS 522
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
Length = 731
Score = 94.7 bits (234), Expect = 5e-19
Identities = 61/199 (30%), Positives = 99/199 (49%), Gaps = 29/199 (14%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG ++ + ++E G VP ++ CI ++KRG V G+YR+ G+ AV ++LR +R+
Sbjct: 520 VFGCQLESLCQRE--GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRE 577
Query: 873 SKAVG-----------------LCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLD 915
L ++ DI+V+TG LK +LRELP PL+ L
Sbjct: 578 RAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRA 637
Query: 916 AMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTC 975
A+A S + + + +L+ +P+ TL+ LL+HL V ++ + N+MT
Sbjct: 638 ALALSESEQCLSQIQ----------ELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTP 687
Query: 976 QNLAVCFGPVLLSQRQEPS 994
NL + FGP L QE S
Sbjct: 688 HNLGIVFGPTLFRPEQETS 706
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
sapiens]
Length = 547
Score = 94.7 bits (234), Expect = 5e-19
Identities = 61/199 (30%), Positives = 99/199 (49%), Gaps = 29/199 (14%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG ++ + ++E G VP ++ CI ++KRG V G+YR+ G+ AV ++LR +R+
Sbjct: 336 VFGCQLESLCQRE--GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRE 393
Query: 873 SKAVG-----------------LCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLD 915
L ++ DI+V+TG LK +LRELP PL+ L
Sbjct: 394 RAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRA 453
Query: 916 AMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTC 975
A+A S + + + +L+ +P+ TL+ LL+HL V ++ + N+MT
Sbjct: 454 ALALSESEQCLSQIQ----------ELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTP 503
Query: 976 QNLAVCFGPVLLSQRQEPS 994
NL + FGP L QE S
Sbjct: 504 HNLGIVFGPTLFRPEQETS 522
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 92.4 bits (228), Expect = 2e-18
Identities = 58/174 (33%), Positives = 92/174 (52%), Gaps = 16/174 (9%)
Query: 814 FGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDS 873
FGV++ ++ ++ VPL+++K I IE G G+YR GS KELR+ + D+
Sbjct: 2061 FGVELSRLTSEDRT---VPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117
Query: 874 KAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDP 933
++V L + +I+VI V K +LR+LP+PL+T +LYE L AM K + G
Sbjct: 2118 ESVNLDDY---NIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRG----- 2169
Query: 934 GDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLL 987
++D L TL+ L+ HL +A + N+M+ LA+ F P +L
Sbjct: 2170 -----VYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCIL 2218
>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
Length = 1261
Score = 89.4 bits (220), Expect = 2e-17
Identities = 66/197 (33%), Positives = 96/197 (48%), Gaps = 21/197 (10%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG + +V +KE G +P +++ C EIE R + G+YR+CG+ ++L +A E
Sbjct: 668 LFGAEFTQVAKKEPDG--IPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENG 725
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLD-AMAKSPLKMSSNGCEN 931
V + E DI VLK YLR+LP P I +LY+ +D A + +N
Sbjct: 726 MHLVDISEFSSHDI---CDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETKKN 782
Query: 932 DPGDSKY-------------TVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNL 978
D K+ + DLL LP +L L+ HLK V + E NKM +NL
Sbjct: 783 SLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNL 842
Query: 979 AVCFGPVLLSQRQEPST 995
V FGP L+ R P+T
Sbjct: 843 GVIFGPSLI--RPRPTT 857
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 87.8 bits (216), Expect = 6e-17
Identities = 63/182 (34%), Positives = 93/182 (51%), Gaps = 13/182 (7%)
Query: 813 IFGVDIQKVV--EKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFE 870
IFG ++ V EK + P+L+++C+ I +RG + GL+RL G A + KEL++AF+
Sbjct: 37 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 96
Query: 871 RDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCE 930
K + D++ + +LK YLRELP P+I YE L S K+ S +
Sbjct: 97 CGEKP---SFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFL-----SCAKLLS---K 145
Query: 931 NDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQR 990
+ K + LP + LK + L V SY VNKM+ QNLA FGP +L +
Sbjct: 146 EEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPK 205
Query: 991 QE 992
E
Sbjct: 206 VE 207
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 87.8 bits (216), Expect = 6e-17
Identities = 63/182 (34%), Positives = 93/182 (51%), Gaps = 13/182 (7%)
Query: 813 IFGVDIQKVV--EKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFE 870
IFG ++ V EK + P+L+++C+ I +RG + GL+RL G A + KEL++AF+
Sbjct: 39 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 98
Query: 871 RDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCE 930
K + D++ + +LK YLRELP P+I YE L S K+ S +
Sbjct: 99 CGEKP---SFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFL-----SCAKLLS---K 147
Query: 931 NDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQR 990
+ K + LP + LK + L V SY VNKM+ QNLA FGP +L +
Sbjct: 148 EEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPK 207
Query: 991 QE 992
E
Sbjct: 208 VE 209
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 87.8 bits (216), Expect = 6e-17
Identities = 63/182 (34%), Positives = 93/182 (51%), Gaps = 13/182 (7%)
Query: 813 IFGVDIQKVV--EKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFE 870
IFG ++ V EK + P+L+++C+ I +RG + GL+RL G A + KEL++AF+
Sbjct: 132 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 191
Query: 871 RDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCE 930
K + D++ + +LK YLRELP P+I YE L S K+ S +
Sbjct: 192 CGEKP---SFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFL-----SCAKLLS---K 240
Query: 931 NDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQR 990
+ K + LP + LK + L V SY VNKM+ QNLA FGP +L +
Sbjct: 241 EEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPK 300
Query: 991 QE 992
E
Sbjct: 301 VE 302
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 86.7 bits (213), Expect = 1e-16
Identities = 66/178 (37%), Positives = 94/178 (52%), Gaps = 16/178 (8%)
Query: 810 EPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAF 869
EP FGV + + + VP++++K + +E G GLYR G+A +ELR+A
Sbjct: 1694 EPGHFGVCVDSLTSDK---ASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQAL 1750
Query: 870 ERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGC 929
+ D AV L +P I+ ITGVLK +LRELP PL+T Y L A+ + P K
Sbjct: 1751 QTDPAAVKL--ENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLRAV-ELPEKQEQLA- 1805
Query: 930 ENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLL 987
+ Y V L+ LPE +L+ L+ HL VA +VN+M+ LA+ F P LL
Sbjct: 1806 ------AIYAV--LEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLL 1855
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 86.7 bits (213), Expect = 1e-16
Identities = 66/178 (37%), Positives = 94/178 (52%), Gaps = 16/178 (8%)
Query: 810 EPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAF 869
EP FGV + + + VP++++K + +E G GLYR G+A +ELR+A
Sbjct: 1694 EPGHFGVCVDSLTSDK---ASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQAL 1750
Query: 870 ERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGC 929
+ D AV L +P I+ ITGVLK +LRELP PL+T Y L A+ + P K
Sbjct: 1751 QTDPAAVKL--ENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLRAV-ELPEKQEQLA- 1805
Query: 930 ENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLL 987
+ Y V L+ LPE +L+ L+ HL VA +VN+M+ LA+ F P LL
Sbjct: 1806 ------AIYAV--LEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLL 1855
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 85.5 bits (210), Expect = 3e-16
Identities = 73/224 (32%), Positives = 104/224 (46%), Gaps = 32/224 (14%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FGVD ++ + VP ++ KC EIE R V G+YR+ GS + L +AFE
Sbjct: 548 LFGVDFLQL--PRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENG 605
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCEND 932
V L N D ++ VLK +L+EL P+I LY+A + ++AK+ D
Sbjct: 606 RALVELSGNSPHD---VSSVLKRFLQELTEPVIPFHLYDAFI-SLAKT--------LHAD 653
Query: 933 PGDSKYTVD-----------LLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVC 981
PGD T LL LP+ TL+ L+ HL VA+ NKM+ NL +
Sbjct: 654 PGDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIV 713
Query: 982 FGPVLLSQRQEPSTHNNRVFT---DSEELASALDFKKHIEVLHY 1022
FGP LL P + T DS A ++F ++HY
Sbjct: 714 FGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFL----IVHY 753
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 85.1 bits (209), Expect = 4e-16
Identities = 60/179 (33%), Positives = 90/179 (50%), Gaps = 13/179 (7%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG D+ + + N G VP ++Q C IE+ G V G+YRL G A+ + LR F+ +
Sbjct: 369 VFGCDLGEHLL--NSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSE 425
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCEND 932
E DI+ + + K Y RELP+PL+T QLYE DA++ + D
Sbjct: 426 HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAA----------TD 475
Query: 933 PGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQ 991
D++ LP TL+ L+ HL L+A Y + M +NLA+ + P LL +Q
Sbjct: 476 EERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQ 534
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 85.1 bits (209), Expect = 4e-16
Identities = 60/179 (33%), Positives = 90/179 (50%), Gaps = 13/179 (7%)
Query: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872
+FG D+ + + N G VP ++Q C IE+ G V G+YRL G A+ + LR F+ +
Sbjct: 20 VFGCDLGEHLL--NSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSE 76
Query: 873 SKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCEND 932
E DI+ + + K Y RELP+PL+T QLYE DA++ + D
Sbjct: 77 HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAA----------TD 126
Query: 933 PGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQ 991
D++ LP TL+ L+ HL L+A Y + M +NLA+ + P LL +Q
Sbjct: 127 EERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQ 185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,308,086
Number of Sequences: 37866
Number of extensions: 2679292
Number of successful extensions: 8107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 270
Number of HSP's that attempted gapping in prelim test: 7435
Number of HSP's gapped (non-prelim): 718
length of query: 1194
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1080
effective length of database: 13,930,794
effective search space: 15045257520
effective search space used: 15045257520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.