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Search of human proteins with 148839292
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148839292 ATPase type 13A3 [Homo sapiens]
(1226 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148839292 ATPase type 13A3 [Homo sapiens] 2464 0.0
gi|66932949 ATPase type 13A4 [Homo sapiens] 993 0.0
gi|66730421 ATPase type 13A5 [Homo sapiens] 905 0.0
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 844 0.0
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 842 0.0
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] 789 0.0
gi|170016077 ATPase type 13A1 [Homo sapiens] 286 1e-76
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 127 8e-29
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 118 4e-26
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 118 4e-26
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 118 4e-26
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 115 3e-25
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 112 2e-24
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 110 1e-23
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 110 1e-23
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 106 2e-22
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 105 3e-22
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 104 6e-22
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 104 6e-22
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 104 6e-22
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 104 6e-22
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 96 3e-19
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 92 2e-18
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 88 4e-17
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 86 2e-16
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 83 1e-15
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 83 2e-15
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 83 2e-15
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 83 2e-15
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 83 2e-15
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 2464 bits (6386), Expect = 0.0
Identities = 1226/1226 (100%), Positives = 1226/1226 (100%)
Query: 1 MDREERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCV 60
MDREERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCV
Sbjct: 1 MDREERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCV 60
Query: 61 RAAIKDCEVVLLRTTDEFKMWFCAKIRVLSLETYPVSSPKSMSNKLSNGHAVCLIENPTE 120
RAAIKDCEVVLLRTTDEFKMWFCAKIRVLSLETYPVSSPKSMSNKLSNGHAVCLIENPTE
Sbjct: 61 RAAIKDCEVVLLRTTDEFKMWFCAKIRVLSLETYPVSSPKSMSNKLSNGHAVCLIENPTE 120
Query: 121 ENRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLT 180
ENRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLT
Sbjct: 121 ENRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLT 180
Query: 181 KGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVV 240
KGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVV
Sbjct: 181 KGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVV 240
Query: 241 MSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLN 300
MSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLN
Sbjct: 241 MSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLN 300
Query: 301 GTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLF 360
GTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLF
Sbjct: 301 GTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLF 360
Query: 361 CGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAV 420
CGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAV
Sbjct: 361 CGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAV 420
Query: 421 AGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFC 480
AGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFC
Sbjct: 421 AGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFC 480
Query: 481 ISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVA 540
ISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVA
Sbjct: 481 ISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVA 540
Query: 541 CMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPE 600
CMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPE
Sbjct: 541 CMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPE 600
Query: 601 STPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAG 660
STPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAG
Sbjct: 601 STPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAG 660
Query: 661 LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLI 720
LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLI
Sbjct: 661 LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLI 720
Query: 721 IMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPK 780
IMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPK
Sbjct: 721 IMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPK 780
Query: 781 DGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILE 840
DGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILE
Sbjct: 781 DGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILE 840
Query: 841 HFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISL 900
HFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISL
Sbjct: 841 HFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISL 900
Query: 901 SELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSIL 960
SELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSIL
Sbjct: 901 SELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSIL 960
Query: 961 SNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGF 1020
SNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGF
Sbjct: 961 SNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGF 1020
Query: 1021 QSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFIS 1080
QSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFIS
Sbjct: 1021 QSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFIS 1080
Query: 1081 SFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPY 1140
SFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPY
Sbjct: 1081 SFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPY 1140
Query: 1141 QWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRKKTPKAKYMYLAQELLVDPEW 1200
QWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRKKTPKAKYMYLAQELLVDPEW
Sbjct: 1141 QWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRKKTPKAKYMYLAQELLVDPEW 1200
Query: 1201 PPKPQTTTEAKALVKENGSCQIITIT 1226
PPKPQTTTEAKALVKENGSCQIITIT
Sbjct: 1201 PPKPQTTTEAKALVKENGSCQIITIT 1226
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 993 bits (2566), Expect = 0.0
Identities = 542/1211 (44%), Positives = 762/1211 (62%), Gaps = 49/1211 (4%)
Query: 2 DREERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVR 61
++ + +N+G+E+EMEI+GY + ++ G I S G L L+ YW P W V A CV
Sbjct: 5 EKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWAHCVP 64
Query: 62 AAIKDCEVVLLRTTDEFKMWFCAKIRVLSLETYPVSSPKSMSNKLSNGHAVCLIENPTEE 121
++++ + VLLRTTDEF+++ K+ + L S + + L+ H + E
Sbjct: 65 CSLQEADTVLLRTTDEFQIYSWKKVIWIYL------SALNSAFGLTPDHPLMTDEE---- 114
Query: 122 NRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTK 181
+ I++ + ++R ++Y WN F + L++ +S I++K +GLT+
Sbjct: 115 --YIINRAIRKPDLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTR 172
Query: 182 GMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVM 241
R+L+ G N I V+V ++KLLIKEVLNPFYIFQLFSV LW +++Y YA AI++M
Sbjct: 173 EEQEIRRLICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIM 232
Query: 242 SIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNG 301
SI+SI ++Y +R+Q V LH +V +H+++ VSVC ++E+ S LVPGD++++ N
Sbjct: 233 SIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNK 292
Query: 302 TIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFC 361
+MPCDAVLI G+C+V+E MLTGES+PVTKT LP V + + +KRH LFC
Sbjct: 293 VLMPCDAVLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPW---KTQSEADYKRHVLFC 349
Query: 362 GTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVA 421
GT VIQ + V+A+V++TGF+T+KG LVRSILYPKP +F+LYRDA FLLCLV A
Sbjct: 350 GTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTA 409
Query: 422 GIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCI 481
IG IYT+ +L+ ++ ++LD+ITI VPPALPAA+T GI+YAQRRLKK GIFCI
Sbjct: 410 TIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCI 469
Query: 482 SPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVAC 541
SPQRIN+CGQLNLVCFDKTGTLT DGLDLWG+ + F + L A
Sbjct: 470 SPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAA 529
Query: 542 MATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPT---VVRPPKQLL 598
MA+CHSL ++G + GDPLDLKMFEA W + + ++ H + +P VV+P +
Sbjct: 530 MASCHSLILLDGTIQGDPLDLKMFEATTWEMAFSGDD---FHIKGVPAHAMVVKPCRT-- 584
Query: 599 PESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAI 658
A +E I I+ QFPFSSALQRM+V+ + +G ++ A+MKGAPE +
Sbjct: 585 -----ASQVPVE--------GIAILHQFPFSSALQRMTVIVQEMGGDRL-AFMKGAPERV 630
Query: 659 AGLCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMG 718
A C+PETVP F + L+ +T QGFRVIALA++KLE+ H ++R+ +E+++ F+G
Sbjct: 631 ASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLEND---HHATTLTRETVESDLIFLG 687
Query: 719 LIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALP 778
L+I++N+LK+ET VLE+L A IRTVM+TGD++ TA++VAR GM+ KVI+ EA
Sbjct: 688 LLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANE 747
Query: 779 PKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVI 838
A I+W + + + + I ++ E YHFA+ GKSF VI
Sbjct: 748 TTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREG----SYHFALTGKSFHVI 803
Query: 839 LEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGI 898
+HF L+PK++++GT+FARM+P QK+ L+E Q +DYFVGMCGDGANDCGALK AH GI
Sbjct: 804 SQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGI 863
Query: 899 SLSELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYS 958
SLSE EASVASPFTSKTP+I CVP+LI+EGRAAL+TSFC+FK+MALYS+IQY V LLY
Sbjct: 864 SLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYW 923
Query: 959 ILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICI 1018
++L ++QFLF DLAI ++ TM+LN A+ +LV RP LIS LL SV+ I++ +
Sbjct: 924 ETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSL 983
Query: 1019 GFQSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHN--IQNYENTTV 1076
GF V++QPWY V AC + E E N ++ENTTV
Sbjct: 984 AMHIAGFILVQRQPWYSV--EIHSACTVQNESISELTMSPTAPEKMESNSTFTSFENTTV 1041
Query: 1077 FFISSFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIV 1136
+F+ + + VA+ FSKGKPFRQP Y NY FV +I LFI+ + + + L ++
Sbjct: 1042 WFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFADIPELYRRLDLL 1101
Query: 1137 CVPYQWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRKKTPKAKYMYLAQELLV 1196
C P WR +++I++ +N VS+ EE+V + C K++Y ++L
Sbjct: 1102 CTPVLWRASIVIMLSLNFIVSLVAEEAVIE-NRALWMMIKRCFGYQSKSQYRIWQRDLAN 1160
Query: 1197 DPEWPPKPQTT 1207
DP WPP QT+
Sbjct: 1161 DPSWPPLNQTS 1171
>gi|66730421 ATPase type 13A5 [Homo sapiens]
Length = 1218
Score = 905 bits (2338), Expect = 0.0
Identities = 505/1219 (41%), Positives = 749/1219 (61%), Gaps = 64/1219 (5%)
Query: 3 REERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRA 62
++ R +NQG+EDE+E++GY + A + + + G LLL+ YW P+WRV A C+
Sbjct: 7 KDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIPC 66
Query: 63 AIKDCEVVLLRTTDEFKMWFCAKIRVLSLET--YPVSSPKSMSNKLSNGHAVCLIENPTE 120
+++ + VLLRTTDEF+ + K+ L L T +PVS K + +++ H+V
Sbjct: 67 PLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSK-KWEESLVADRHSV-------- 117
Query: 121 ENRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLT 180
I++ ++R ++Y WND F + L++ SC+ I++ GLT
Sbjct: 118 -----INQALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLT 172
Query: 181 KGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVV 240
R+L+ G N I V++ ++KLL+K+VLNPFY+FQ F++ LW + Y Y++AI++
Sbjct: 173 SEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIII 232
Query: 241 MSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLN 300
++++SIV S+Y +R+Q V LH++V H+ V+V++ ++ +EE+ S LVPGD++++P
Sbjct: 233 LTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGK 292
Query: 301 GTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLF 360
++ PCDAVLI+G+C+VNE MLTGES+PVTKT LP + + ++ E +++H LF
Sbjct: 293 FSL-PCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPW---KCHSLEDYRKHVLF 348
Query: 361 CGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAV 420
CGT VIQ + V+A+V++TG++T+KG LVRSILYP+P +FKLY DA+ F++ L +
Sbjct: 349 CGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACL 408
Query: 421 AGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFC 480
+GF Y + + + V + +L ++T+TVPP LPAA+T G VYAQ+RLKK IFC
Sbjct: 409 GVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFC 468
Query: 481 ISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVA 540
ISPQRIN+CGQ+NLVCFDKTGTLTEDGLDLWG + F + + S A
Sbjct: 469 ISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCA 528
Query: 541 CMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPE 600
MA+CHSL + G + GDPLDLKMFE W +E+ + + + PK
Sbjct: 529 AMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPK----- 583
Query: 601 STPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAG 660
A +E I + QFPFSS+LQRMSV+A++ G+ YMKGAPE +A
Sbjct: 584 ---ASKSPVEA--------IITLCQFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVAR 632
Query: 661 LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLI 720
C+ ETVP +F L +T QGFRVIALAH+ L+ +V++++R+ +E+ + F+GL+
Sbjct: 633 FCRSETVPKNFPQELRSYTVQGFRVIALAHKTLKMG-NLSEVEHLAREKVESELTFLGLL 691
Query: 721 IMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPK 780
IM+N+LK+ET VL++L +A IRTVM+TGD++ TA++VA++ MI P +VII EA P+
Sbjct: 692 IMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPE 751
Query: 781 DGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTR------YHFAMNGKS 834
+ A + W ++ Q + P K ++ + R YHFAM+GKS
Sbjct: 752 EFVPASVTWQLVEN--QETGPGK--------KEIYMHTGNSSTPRGEGGSCYHFAMSGKS 801
Query: 835 FSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRA 894
+ VI +HF L+PK++++GTVFARM+P QK+ LIE Q ++Y+VGMCGDGANDCGALK A
Sbjct: 802 YQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAA 861
Query: 895 HGGISLSELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVT 954
H GISLSE EASVASPFTSKT +I CVP+LIREGRAAL++SF VFK++ +Y IIQ+ S
Sbjct: 862 HAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISAL 921
Query: 955 LLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSV-LSQ 1013
LLY L G++Q+L D+AI L+V TMS A+ +L RP L+S LL S+ L+
Sbjct: 922 LLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLSIFLNS 981
Query: 1014 IIICIGFQSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVD----NETELDEHNIQ 1069
CI Q F +VKQQPWY + S+ S F + ++ L +I
Sbjct: 982 CFSCI-VQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSIL 1040
Query: 1070 NYENTTVFFISSFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASV 1129
++E TT++ I++ Y+ VA FSKGKPFR+P Y NY F F ++ +FI+ +
Sbjct: 1041 SFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVI 1100
Query: 1130 DQVLQIVCVPYQWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRK--KTPKAKY 1187
+ ++++ WRV +L++ L V+ VE+S+ + + W L R+ K++Y
Sbjct: 1101 YRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHEL---WLLIKREFGFYSKSQY 1157
Query: 1188 MYLAQELLVDPEWPPKPQT 1206
++L D WPP +T
Sbjct: 1158 RTWQKKLAEDSTWPPINRT 1176
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 844 bits (2181), Expect = 0.0
Identities = 494/1196 (41%), Positives = 704/1196 (58%), Gaps = 68/1196 (5%)
Query: 17 MEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRTTD 76
+ + GY S W++ + V G LLL W P W V+ + E +++ D
Sbjct: 35 VRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD 94
Query: 77 -EFKMW--FCAKIRVLSL-ETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISKYSQT 132
E W F +++ ++ E SP+S + + AV + ++ ++ K S+
Sbjct: 95 KEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHK-SEE 153
Query: 133 ESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYG 192
+ +RY+ +Y W +T F + LD G SC ++ GL+ RK +YG
Sbjct: 154 AKRVLRYYLFQGQRYIWIETQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYG 212
Query: 193 VNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSLYS 252
N I++ V S +LL+ E LNP+Y FQ FS+ LW D YY+YAL I ++S +SI SLY
Sbjct: 213 PNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYK 272
Query: 253 IRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLIN 312
RKQ L DMV ++RV VCR E E + S++LVPGD +V+P G +MPCDA L+
Sbjct: 273 TRKQSQTLRDMVKL--SMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330
Query: 313 GTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYT 372
G C+VNES LTGES+PV KT LP +G+G Y ETH+RHTLFCGT ++Q R Y
Sbjct: 331 GECMVNESSLTGESIPVLKTALP------EGLGP--YCAETHRRHTLFCGTLILQARAYV 382
Query: 373 GELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINS 432
G V A+V RTGF T+KG LV SIL+P+P +FK Y+ + F+ L +A +G IY+I
Sbjct: 383 GPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFIL 442
Query: 433 ILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQL 492
N V + I+I +LD++T+ VPPALPAAMT +YAQ RL++ GIFCI P RIN+ G+L
Sbjct: 443 YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKL 502
Query: 493 NLVCFDKTGTLTEDGLDLWGIQRVENARFLS--PEENVCNEMLVKSQFVACMATCHSLTK 550
LVCFDKTGTLTEDGLD+ G+ ++ FL PE L + +ATCH+L++
Sbjct: 503 QLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPR----RLPVGPLLRALATCHALSR 558
Query: 551 IEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEME 610
++ GDP+DLKM E+ GW+LEE ++A +++ V+RPP +++
Sbjct: 559 LQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL-AVMRPP---------LWEPQLQ 608
Query: 611 LFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVD 670
E P + ++ +FPFSSALQRMSVV G + +AY+KG+PE +AGLC PETVP D
Sbjct: 609 AMEEPPV-PVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNPETVPTD 667
Query: 671 FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQET 730
F +L+ +T G+RV+ALA + L + + Q ++RD +E ++ +GL++M+N LK +T
Sbjct: 668 FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQT 727
Query: 731 PAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWH 790
V++ L + IR VMVTGD++ TAV+VAR CGM+ PQ+ +II A P+ G+ A + +
Sbjct: 728 TPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFL 787
Query: 791 YADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLM 850
+S P+A++ P + ++E +R H A++G +F +I++HF L+PK++
Sbjct: 788 PMES------PTAVNGVKDPDQAASYTVEPDPRSR-HLALSGPTFGIIVKHFPKLLPKVL 840
Query: 851 LHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASP 910
+ GTVFARMAP+QKT+L+ LQ + Y VGMCGDGANDCGALK A GISLS+ EASV SP
Sbjct: 841 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900
Query: 911 FTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLF 970
FTS SI CVP +IREGR +L TSF VFK+MALYS+ Q+ SV +LY+I +NLGD QFL
Sbjct: 901 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960
Query: 971 IDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFFWVKQ 1030
IDL I V MS L RPP L+S +L S+L Q+++ G Q G+F
Sbjct: 961 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020
Query: 1031 QPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQYLIVAIA 1090
QPW+ N T N+ NYENT VF +SSFQYLI+A A
Sbjct: 1021 QPWFVPL---------------------NRTVAAPDNLPNYENTVVFSLSSFQYLILAAA 1059
Query: 1091 FSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQWRVTMLIIV 1150
SKG PFR+P Y N F+ ++ L ++ ++L P + +++ +L +V
Sbjct: 1060 VSKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLV 1119
Query: 1151 LVNAFVSITVEESVDRWGKCCLPWALG--CRKKTPKAKYMYLAQELLVDPEWPPKP 1204
+N + +E +D+ CLP L K+ K ++ L +EL P WPP P
Sbjct: 1120 TLNFVGAFMLESVLDQ----CLPACLRRLRPKRASKKRFKQLERELAEQP-WPPLP 1170
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 842 bits (2176), Expect = 0.0
Identities = 494/1200 (41%), Positives = 698/1200 (58%), Gaps = 71/1200 (5%)
Query: 17 MEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRTTD 76
+ + GY S W++ + V G LLL W P W V+ + E +++ D
Sbjct: 35 VRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD 94
Query: 77 -EFKMWFCAKIRVL-------SLETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISK 128
E W ++V SLE P S + ++ + G T +
Sbjct: 95 KEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA 154
Query: 129 YSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRK 188
S + + +RY+ +Y W +T F + LD G SC ++ GL+ RK
Sbjct: 155 VSVGQKRVLRYYLFQGQRYIWIETQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRK 213
Query: 189 LLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVS 248
+YG N I++ V S +LL+ E LNP+Y FQ FS+ LW D YY+YAL I ++S +SI
Sbjct: 214 AIYGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICL 273
Query: 249 SLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDA 308
SLY RKQ L DMV ++RV VCR E E + S++LVPGD +V+P G +MPCDA
Sbjct: 274 SLYKTRKQSQTLRDMVKL--SMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDA 331
Query: 309 VLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQT 368
L+ G C+VNES LTGES+PV KT LP +G+G Y ETH+RHTLFCGT ++Q
Sbjct: 332 ALVAGECMVNESSLTGESIPVLKTALP------EGLGP--YCAETHRRHTLFCGTLILQA 383
Query: 369 RFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYT 428
R Y G V A+V RTGF T+KG LV SIL+P+P +FK Y+ + F+ L +A +G IY+
Sbjct: 384 RAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYS 443
Query: 429 IINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINI 488
I N V + I+I +LD++T+ VPPALPAAMT +YAQ RL++ GIFCI P RIN+
Sbjct: 444 IFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINL 503
Query: 489 CGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLS--PEENVCNEMLVKSQFVACMATCH 546
G+L LVCFDKTGTLTEDGLD+ G+ ++ FL PE L + +ATCH
Sbjct: 504 GGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPR----RLPVGPLLRALATCH 559
Query: 547 SLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGN 606
+L++++ GDP+DLKM E+ GW+LEE ++A +++ V+RPP
Sbjct: 560 ALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL-AVMRPP---------LWE 609
Query: 607 QEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPET 666
+++ E P + ++ +FPFSSALQRMSVV G + +AY+KG+PE +AGLC PET
Sbjct: 610 PQLQAMEEPPV-PVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNPET 668
Query: 667 VPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKL 726
VP DF +L+ +T G+RV+ALA + L + + Q ++RD +E ++ +GL++M+N L
Sbjct: 669 VPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLL 728
Query: 727 KQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAK 786
K +T V++ L + IR VMVTGD++ TAV+VAR CGM+ PQ+ +II A P+ G+ A
Sbjct: 729 KPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPAS 788
Query: 787 INWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLV 846
+ + +S P+A++ P + ++E +R H A++G +F +I++HF L+
Sbjct: 789 LEFLPMES------PTAVNGVKDPDQAASYTVEPDPRSR-HLALSGPTFGIIVKHFPKLL 841
Query: 847 PKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEAS 906
PK+++ GTVFARMAP+QKT+L+ LQ + Y VGMCGDGANDCGALK A GISLS+ EAS
Sbjct: 842 PKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEAS 901
Query: 907 VASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDF 966
V SPFTS SI CVP +IREGR +L TSF VFK+MALYS+ Q+ SV +LY+I +NLGD
Sbjct: 902 VVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDL 961
Query: 967 QFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFF 1026
QFL IDL I V MS L RPP L+S +L S+L Q+++ G Q G+F
Sbjct: 962 QFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYF 1021
Query: 1027 WVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQYLI 1086
QPW+ N T N+ NYENT VF +SSFQYLI
Sbjct: 1022 LTLAQPWFVPL---------------------NRTVAAPDNLPNYENTVVFSLSSFQYLI 1060
Query: 1087 VAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQWRVTM 1146
+A A SKG PFR+P Y N F+ ++ L ++ ++L P + +++ +
Sbjct: 1061 LAAAVSKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLL 1120
Query: 1147 LIIVLVNAFVSITVEESVDRWGKCCLPWALG--CRKKTPKAKYMYLAQELLVDPEWPPKP 1204
L +V +N + +E +D+ CLP L K+ K ++ L +EL P WPP P
Sbjct: 1121 LGLVTLNFVGAFMLESVLDQ----CLPACLRRLRPKRASKKRFKQLERELAEQP-WPPLP 1175
>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
Length = 1158
Score = 789 bits (2038), Expect = 0.0
Identities = 461/1094 (42%), Positives = 636/1094 (58%), Gaps = 100/1094 (9%)
Query: 17 MEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRTTD 76
+ + GY S W++ + V G LLL W P W V+ + E +++ D
Sbjct: 35 VRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD 94
Query: 77 -EFKMW--FCAKIRVLSL-ETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISKYSQT 132
E W F +++ ++ E SP+S + + AV + ++ ++ K S+
Sbjct: 95 KEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHK-SEE 153
Query: 133 ESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYG 192
+ +RY+ +Y W +T F + LD G SC ++ GL+ RK +YG
Sbjct: 154 AKRVLRYYLFQGQRYIWIETQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYG 212
Query: 193 VNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSLYS 252
N I++ V S +LL+ E LNP+Y FQ FS+ LW D YY+YAL I ++S +SI SLY
Sbjct: 213 PNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYK 272
Query: 253 IRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLIN 312
RKQ L DMV ++RV VCR E E + S++LVPGD +V+P G +MPCDA L+
Sbjct: 273 TRKQSQTLRDMVKL--SMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330
Query: 313 GTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYT 372
G C+VNES LTGES+PV KT LP +G+G Y ETH+RHTLFCGT ++Q R Y
Sbjct: 331 GECMVNESSLTGESIPVLKTALP------EGLGP--YCAETHRRHTLFCGTLILQARAYV 382
Query: 373 GELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINS 432
G V A+V RTGF T+KG LV SIL+P+P +FK Y+ + F+ L +A +G IY+I
Sbjct: 383 GPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFIL 442
Query: 433 ILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQL 492
N V + I+I +LD++T+ VPPALPAAMT +YAQ RL++ GIFCI P RIN+ G+L
Sbjct: 443 YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKL 502
Query: 493 NLVCFDKTGTLTEDGLDLWGIQRVENARFLS--PEENVCNEMLVKSQFVACMATCHSLTK 550
LVCFDKTGTLTEDGLD+ G+ ++ FL PE L + +ATCH+L++
Sbjct: 503 QLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEP----RRLPVGPLLRALATCHALSR 558
Query: 551 IEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEME 610
++ GDP+DLKM E+ GW+LEE ++A +++ V+RP P +++
Sbjct: 559 LQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL-AVMRP---------PLWEPQLQ 608
Query: 611 LFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVD 670
E P + ++ +FPFSSALQRMSVV G + +AY+KG+PE +AGLC PETVP D
Sbjct: 609 AMEEPPV-PVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNPETVPTD 667
Query: 671 FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQET 730
F +L+ +T G+RV+ALA + L + + Q ++RD +E ++ +GL++M+N LK +T
Sbjct: 668 FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQT 727
Query: 731 PAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWH 790
V++ L + IR VMVTGD++ TAV+VAR CGM+ PQ+ +II A P+ G+ A + +
Sbjct: 728 TPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFL 787
Query: 791 YADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLM 850
+S T A+NG K++
Sbjct: 788 PMESPT--------------------------------AVNG--------------VKVL 801
Query: 851 LHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASP 910
+ GTVFARMAP+QKT+L+ LQ + Y VGMCGDGANDCGALK A GISLS+ EASV SP
Sbjct: 802 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 861
Query: 911 FTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLF 970
FTS SI CVP +IREGR +L TSF VFK+MALYS+ Q+ SV +LY+I +NLGD QFL
Sbjct: 862 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 921
Query: 971 IDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFFWVKQ 1030
IDL I V MS L RPP L+S +L S+L Q+++ G Q G+F
Sbjct: 922 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 981
Query: 1031 QPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQYLIVAIA 1090
QPW+ N T N+ NYENT VF +SSFQYLI+A A
Sbjct: 982 QPWFVPL---------------------NRTVAAPDNLPNYENTVVFSLSSFQYLILAAA 1020
Query: 1091 FSKGKPFRQPCYKN 1104
SKG PFR+P Y N
Sbjct: 1021 VSKGAPFRRPLYTN 1034
>gi|170016077 ATPase type 13A1 [Homo sapiens]
Length = 1204
Score = 286 bits (731), Expect = 1e-76
Identities = 222/732 (30%), Positives = 365/732 (49%), Gaps = 94/732 (12%)
Query: 191 YGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSL 250
+G N+ + VP +L + PF++FQ+F V LW DEY+YY++ + M + S +
Sbjct: 222 FGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLV 281
Query: 251 YSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNG--TIMPCDA 308
+ + M ++V R + I S ++VPGD++ I + ++PCD
Sbjct: 282 QQQMRNMSEIRKMGNKPHMIQVYRSR---KWRPIASDEIVPGDIVSIGRSPQENLVPCDV 338
Query: 309 VLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKR-HTLFCGTTVIQ 367
+L+ G CIV+E+MLTGESVP K + + S D + + + R H +F GT V+Q
Sbjct: 339 LLLRGRCIVDEAMLTGESVPQMKEPIEDLSPD------RVLDLQADSRLHVIFGGTKVVQ 392
Query: 368 ----TRFYTG-----ELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLV 418
+ TG A V+RTGF+TS+G+L+R+IL+ + ++F+L L+
Sbjct: 393 HIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLL 452
Query: 419 AVAGIGFIYTIINSILNEVQVGV-IIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIG 477
A Y I + + + +E I+T VPP LP ++ + + L K+
Sbjct: 453 VFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLY 512
Query: 478 IFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQ 537
++C P RI G++ + CFDKTGTLT D L + G+ + + + ++P ++ E
Sbjct: 513 MYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDGKEVTPVSSIPVET----- 567
Query: 538 FVACMATCHSLTKI-EGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQ 596
+A+CHSL ++ +G L GDPL+ M A+ W L T++E ++ P ++
Sbjct: 568 -HRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTL---TKDE-----KVFPRSIK---- 614
Query: 597 LLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVA--RVLG--DRKMDAYMK 652
T + I ++F F+SAL+RMSV+A LG D A +K
Sbjct: 615 --------------------TQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVK 654
Query: 653 GAPEAIAGLCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIEN 712
GAPE + + P D+ ++ + +++G RV+AL +++L LT + + + R+A+E
Sbjct: 655 GAPETLHSMF--SQCPPDYHHIHTEISREGARVLALGYKEL-GHLTHQQAREVKREALEC 711
Query: 713 NMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVI 772
++ F+G I++ LK ++ AV+ ++ A+ R VM+TGD+ LTA VA++ I +I
Sbjct: 712 SLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLI 771
Query: 773 IAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNG 832
L P K + W D +I + L S + L + Y + G
Sbjct: 772 ----LQPPSEKGRQCEWRSIDG-------------SIVLPLARGSPKALAL-EYALCLTG 813
Query: 833 KSFSVILEHFQDLVPKLML----HGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDC 888
L H Q P+ +L H VFAR+AP QK +I +L+ + Y MCGDG ND
Sbjct: 814 DG----LAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDV 869
Query: 889 GALKRAHGGISL 900
GALK A G++L
Sbjct: 870 GALKHADVGVAL 881
Score = 71.2 bits (173), Expect = 6e-12
Identities = 59/258 (22%), Positives = 119/258 (46%), Gaps = 22/258 (8%)
Query: 904 EASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNL 963
+AS+A+PFTSK SI C+ ++I++GR L+T+ +FK +AL ++I +S ++LY
Sbjct: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
Query: 964 GDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSL 1023
DFQ L + +F P K L +RP + + + +V+ Q + F SL
Sbjct: 1013 SDFQATLQGLLLAGCFLFISRSKPL-KTLSRERPLPNIFNLYTILTVMLQFF--VHFLSL 1069
Query: 1024 GFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQ 1083
+ + + Q S VD E + + N+TV+ ++
Sbjct: 1070 VYLYREAQ---------------ARSPEKQEQFVDLYKEFEPSLV----NSTVYIMAMAM 1110
Query: 1084 YLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQWR 1143
+ KG PF + +N V+S+ + I+ ++L + +V +P +++
Sbjct: 1111 QMATFAINYKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVEFK 1170
Query: 1144 VTMLIIVLVNAFVSITVE 1161
+ + ++L++ +++ +
Sbjct: 1171 LVIAQVLLLDFCLALLAD 1188
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 127 bits (318), Expect = 8e-29
Identities = 206/883 (23%), Positives = 356/883 (40%), Gaps = 139/883 (15%)
Query: 163 DEGVSCTSIYEKHSAGLTKGMHAYRK---LLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQ 219
D ++ + K+S LTKG H++++ +L V P +K +F
Sbjct: 51 DHKLTLEELSTKYSVDLTKG-HSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQ---LFG 106
Query: 220 LFSVILWSTDEYYYYALAI----------------VVMSIVSIVSSLYSIRKQYVMLHDM 263
FS++LW+ + A +I +V+S+V IV+ +S ++ M
Sbjct: 107 GFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIM 166
Query: 264 VATHSTV--RVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGT-CIVNES 320
+ + V + V R E+++ I ++V GD++ I G +P D LI+ C V+ S
Sbjct: 167 ESFKNMVPQQALVIRGGEKMQ-INVQEVVLGDLVEIK-GGDRVPADLRLISAQGCKVDNS 224
Query: 321 MLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIV 380
LTGES P +++ D + R+ F T ++ + IV
Sbjct: 225 SLTGESEPQSRSP------------DFTHENPLETRNICFFSTNCVEGT------ARGIV 266
Query: 381 VRTGFSTSKGQL--VRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNEVQ 438
+ TG ST G++ + S L T + ++ L+ +VAV +G + ++ +L
Sbjct: 267 IATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVF-LGVTFFALSLLLGYGW 325
Query: 439 VGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFD 498
+ II + II VP L A +T + +R+ + + + + G + +C D
Sbjct: 326 LEAIIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD 384
Query: 499 KTGTLTEDGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEGVL 555
KTGTLT++ + +W V A + E K+ F T L +I G+
Sbjct: 385 KTGTLTQNRMTVAHMWFDMTVYEA-------DTTEEQTGKT-FTKSSDTWFMLARIAGLC 436
Query: 556 SGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEMELFELP 615
+ D K + I I + AT + + LL + + E+ E
Sbjct: 437 NR--ADFKANQEILPIAKRATTGDAS------------ESALLKFIEQSYSSVAEMREKN 482
Query: 616 ATYEIGIVRQFPFSSALQ-RMSVVARVLGDRKMDAYMKGAPEAIAGLCKP---------- 664
V + PF+S + +MS+ R + MKGAPE I C
Sbjct: 483 PK-----VAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSM 537
Query: 665 -ETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMD---FMGLI 720
+ + FQN + G RV+ L S + K + D I MD F+GLI
Sbjct: 538 NDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFS--KGFPFNTDEINFPMDNLCFVGLI 595
Query: 721 IMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPK 780
M + + P + A I+ +MVTGD +TA ++A+ G II+E
Sbjct: 596 SMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IISEGTETA 647
Query: 781 DGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDS-LEDLQMTRYHFAMNGKSFSVIL 839
+ A++ S +D A +VH + L+D+Q K IL
Sbjct: 648 EEVAARLKIPI----------SKVDASAAKAIVVHGAELKDIQ---------SKQLDQIL 688
Query: 840 EHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGIS 899
++ ++V FAR +P QK ++E Q + V + GDG ND ALK+A GI+
Sbjct: 689 QNHPEIV---------FARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIA 739
Query: 900 LSELEASV---ASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFKFMALYSIIQYFSVT 954
+ + V A+ + + + + EGR + ++ + I F +
Sbjct: 740 MGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMF 799
Query: 955 LLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRP 997
++ I LG L IDL +V +++ A +++ + P
Sbjct: 800 IILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP 842
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
Length = 1023
Score = 118 bits (295), Expect = 4e-26
Identities = 207/922 (22%), Positives = 367/922 (39%), Gaps = 154/922 (16%)
Query: 163 DEGVSCTSIYEKHSAGLTKGMHAYR--KLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQL 220
D +S ++ K+ L++G+ + R ++L A+ P IK +F
Sbjct: 43 DHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQ---LFGG 99
Query: 221 FSVILWSTDEYYYYALAI----------------VVMSIVSIVSSLYSIRKQYVMLHDMV 264
FS++LW + A +I VV+S V I++ +S ++ M
Sbjct: 100 FSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIME 159
Query: 265 ATHSTVRVSVCRV-NEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGT-CIVNESML 322
+ + V + N E I + ++V GD++ + G +P D +I+ C V+ S L
Sbjct: 160 SFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVK-GGDRIPADLRIISANGCKVDNSSL 218
Query: 323 TGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVR 382
TGES P T++ D R+ F T ++ + IVV
Sbjct: 219 TGESEPQTRSP------------DFTNENPLETRNIAFFSTNCVEGT------ARGIVVY 260
Query: 383 TGFSTSKGQL--VRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNEVQVG 440
TG T G++ + S L T + ++ ++ VAV +G + I++ IL +
Sbjct: 261 TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVF-LGVSFFILSLILEYTWLE 319
Query: 441 VIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKT 500
+I + II VP L A +T + +R+ + + + + G + +C DKT
Sbjct: 320 AVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKT 378
Query: 501 GTLTEDGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEGVLSG 557
GTLT++ + +W ++ A + V F AT +L++I G+ +
Sbjct: 379 GTLTQNRMTVAHMWFDNQIHEADTTENQSGV--------SFDKTSATWLALSRIAGLCNR 430
Query: 558 DPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGN-QEM-----EL 611
+ +A +E + R + L G+ +EM ++
Sbjct: 431 -------------AVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKI 477
Query: 612 FELPAT----YEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKP--- 664
E+P Y++ I + P +S Q + V MKGAPE I C
Sbjct: 478 VEIPFNSTNKYQLSIHKN-PNTSEPQHLLV-------------MKGAPERILDRCSSILL 523
Query: 665 --ETVPVD------FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIE--NNM 714
+ P+D FQN + G RV+ H L + Q + D +N+
Sbjct: 524 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNL 583
Query: 715 DFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIA 774
F+GLI M + + P + A I+ +MVTGD +TA ++A+ G II+
Sbjct: 584 CFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IIS 635
Query: 775 EALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKS 834
E + A++N S ++P +VH S DL+ M +
Sbjct: 636 EGNETVEDIAARLNIPV----------SQVNPRDAKACVVHGS--DLK------DMTSEQ 677
Query: 835 FSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRA 894
IL++ ++V FAR +P QK ++E Q V + GDG ND ALK+A
Sbjct: 678 LDDILKYHTEIV---------FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA 728
Query: 895 HGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFKFMALYSIIQ 949
G+++ + V A+ + + + + EGR + + + I
Sbjct: 729 DIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 788
Query: 950 YFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRP----PSGLISGA 1005
F + ++ +I LG L IDL +V +++ A +++ ++P L++
Sbjct: 789 PFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNER 848
Query: 1006 LLFSVLSQIIICIGFQSLGFFW 1027
L+ QI + Q+LG F+
Sbjct: 849 LISMAYGQIGM---IQALGGFF 867
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens]
Length = 992
Score = 118 bits (295), Expect = 4e-26
Identities = 207/922 (22%), Positives = 367/922 (39%), Gaps = 154/922 (16%)
Query: 163 DEGVSCTSIYEKHSAGLTKGMHAYR--KLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQL 220
D +S ++ K+ L++G+ + R ++L A+ P IK +F
Sbjct: 12 DHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQ---LFGG 68
Query: 221 FSVILWSTDEYYYYALAI----------------VVMSIVSIVSSLYSIRKQYVMLHDMV 264
FS++LW + A +I VV+S V I++ +S ++ M
Sbjct: 69 FSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIME 128
Query: 265 ATHSTVRVSVCRV-NEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGT-CIVNESML 322
+ + V + N E I + ++V GD++ + G +P D +I+ C V+ S L
Sbjct: 129 SFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVK-GGDRIPADLRIISANGCKVDNSSL 187
Query: 323 TGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVR 382
TGES P T++ D R+ F T ++ + IVV
Sbjct: 188 TGESEPQTRSP------------DFTNENPLETRNIAFFSTNCVEGT------ARGIVVY 229
Query: 383 TGFSTSKGQL--VRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNEVQVG 440
TG T G++ + S L T + ++ ++ VAV +G + I++ IL +
Sbjct: 230 TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVF-LGVSFFILSLILEYTWLE 288
Query: 441 VIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKT 500
+I + II VP L A +T + +R+ + + + + G + +C DKT
Sbjct: 289 AVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKT 347
Query: 501 GTLTEDGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEGVLSG 557
GTLT++ + +W ++ A + V F AT +L++I G+ +
Sbjct: 348 GTLTQNRMTVAHMWFDNQIHEADTTENQSGV--------SFDKTSATWLALSRIAGLCNR 399
Query: 558 DPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGN-QEM-----EL 611
+ +A +E + R + L G+ +EM ++
Sbjct: 400 -------------AVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKI 446
Query: 612 FELPAT----YEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKP--- 664
E+P Y++ I + P +S Q + V MKGAPE I C
Sbjct: 447 VEIPFNSTNKYQLSIHKN-PNTSEPQHLLV-------------MKGAPERILDRCSSILL 492
Query: 665 --ETVPVD------FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIE--NNM 714
+ P+D FQN + G RV+ H L + Q + D +N+
Sbjct: 493 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNL 552
Query: 715 DFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIA 774
F+GLI M + + P + A I+ +MVTGD +TA ++A+ G II+
Sbjct: 553 CFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IIS 604
Query: 775 EALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKS 834
E + A++N S ++P +VH S DL+ M +
Sbjct: 605 EGNETVEDIAARLNIPV----------SQVNPRDAKACVVHGS--DLK------DMTSEQ 646
Query: 835 FSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRA 894
IL++ ++V FAR +P QK ++E Q V + GDG ND ALK+A
Sbjct: 647 LDDILKYHTEIV---------FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA 697
Query: 895 HGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFKFMALYSIIQ 949
G+++ + V A+ + + + + EGR + + + I
Sbjct: 698 DIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 757
Query: 950 YFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRP----PSGLISGA 1005
F + ++ +I LG L IDL +V +++ A +++ ++P L++
Sbjct: 758 PFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNER 817
Query: 1006 LLFSVLSQIIICIGFQSLGFFW 1027
L+ QI + Q+LG F+
Sbjct: 818 LISMAYGQIGM---IQALGGFF 836
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 118 bits (295), Expect = 4e-26
Identities = 207/922 (22%), Positives = 367/922 (39%), Gaps = 154/922 (16%)
Query: 163 DEGVSCTSIYEKHSAGLTKGMHAYR--KLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQL 220
D +S ++ K+ L++G+ + R ++L A+ P IK +F
Sbjct: 43 DHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQ---LFGG 99
Query: 221 FSVILWSTDEYYYYALAI----------------VVMSIVSIVSSLYSIRKQYVMLHDMV 264
FS++LW + A +I VV+S V I++ +S ++ M
Sbjct: 100 FSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIME 159
Query: 265 ATHSTVRVSVCRV-NEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGT-CIVNESML 322
+ + V + N E I + ++V GD++ + G +P D +I+ C V+ S L
Sbjct: 160 SFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVK-GGDRIPADLRIISANGCKVDNSSL 218
Query: 323 TGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVR 382
TGES P T++ D R+ F T ++ + IVV
Sbjct: 219 TGESEPQTRSP------------DFTNENPLETRNIAFFSTNCVEGT------ARGIVVY 260
Query: 383 TGFSTSKGQL--VRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNEVQVG 440
TG T G++ + S L T + ++ ++ VAV +G + I++ IL +
Sbjct: 261 TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVF-LGVSFFILSLILEYTWLE 319
Query: 441 VIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKT 500
+I + II VP L A +T + +R+ + + + + G + +C DKT
Sbjct: 320 AVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKT 378
Query: 501 GTLTEDGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEGVLSG 557
GTLT++ + +W ++ A + V F AT +L++I G+ +
Sbjct: 379 GTLTQNRMTVAHMWFDNQIHEADTTENQSGV--------SFDKTSATWLALSRIAGLCNR 430
Query: 558 DPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGN-QEM-----EL 611
+ +A +E + R + L G+ +EM ++
Sbjct: 431 -------------AVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKI 477
Query: 612 FELPAT----YEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKP--- 664
E+P Y++ I + P +S Q + V MKGAPE I C
Sbjct: 478 VEIPFNSTNKYQLSIHKN-PNTSEPQHLLV-------------MKGAPERILDRCSSILL 523
Query: 665 --ETVPVD------FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIE--NNM 714
+ P+D FQN + G RV+ H L + Q + D +N+
Sbjct: 524 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNL 583
Query: 715 DFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIA 774
F+GLI M + + P + A I+ +MVTGD +TA ++A+ G II+
Sbjct: 584 CFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IIS 635
Query: 775 EALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKS 834
E + A++N S ++P +VH S DL+ M +
Sbjct: 636 EGNETVEDIAARLNIPV----------SQVNPRDAKACVVHGS--DLK------DMTSEQ 677
Query: 835 FSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRA 894
IL++ ++V FAR +P QK ++E Q V + GDG ND ALK+A
Sbjct: 678 LDDILKYHTEIV---------FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA 728
Query: 895 HGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFKFMALYSIIQ 949
G+++ + V A+ + + + + EGR + + + I
Sbjct: 729 DIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 788
Query: 950 YFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRP----PSGLISGA 1005
F + ++ +I LG L IDL +V +++ A +++ ++P L++
Sbjct: 789 PFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNER 848
Query: 1006 LLFSVLSQIIICIGFQSLGFFW 1027
L+ QI + Q+LG F+
Sbjct: 849 LISMAYGQIGM---IQALGGFF 867
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 115 bits (288), Expect = 3e-25
Identities = 206/908 (22%), Positives = 372/908 (40%), Gaps = 166/908 (18%)
Query: 154 HNFDFLKGL---DEGVSCTSIYEKHSAGLTKGMHAYR--KLLY--GVNEIAV--KVPSVF 204
H +F K L D +S + EK+ + G+ + R +LL G N + + P +
Sbjct: 46 HKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIV 105
Query: 205 KLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAI----------------VVMSIVSIVS 248
K L + V FS++LW + A I V+ +V I++
Sbjct: 106 KFLKQMVGG-------FSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILT 158
Query: 249 SLYSIRKQYVMLHDMVATHSTVRVSVCRVNE-EIEEIFSTDLVPGDVMVIPLNGTIMPCD 307
+++ ++ + M + + + + + E + I S LV GD++ + G +P D
Sbjct: 159 GIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVK-GGDQIPAD 217
Query: 308 A-VLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVI 366
VL + C V+ S LTGES P +++ + + ++ F TT +
Sbjct: 218 IRVLSSQGCRVDNSSLTGESEPQPRSS------------EFTHENPLETKNICFYSTTCL 265
Query: 367 QTRFYTGELVKAIVVRTGFSTSKGQL--VRSILYPKPTDFKLYRDAYLFLLCLVAVAGIG 424
+ V +V+ TG T G + + S + + T + + ++ ++ VAV+ IG
Sbjct: 266 EGT------VTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVS-IG 318
Query: 425 FIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQ 484
++ II ++ + QV II + II VP L A +T + +R+ K + +
Sbjct: 319 ILFFII-AVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLE 377
Query: 485 RINICGQLNLVCFDKTGTLTEDGL---DLWGIQRVENARFLS-PEENVCNEMLVKSQFVA 540
+ G +++C DKTGTLT++ + LW +N F++ E+ N++ +S
Sbjct: 378 AVETLGSTSIICSDKTGTLTQNRMTVAHLW----FDNQIFVADTSEDHSNQVFDQSS--- 430
Query: 541 CMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEAT---EEETALHNRIMPTVVRPPKQL 597
T SL+KI + + + K + I+++A ETA L
Sbjct: 431 --RTWASLSKI--ITLCNRAEFKPGQENVPIMKKAVIGDASETA---------------L 471
Query: 598 LPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGD---RKMDAYMKGA 654
L S ME+ + V + PF+S + + + D ++ MKGA
Sbjct: 472 LKFSEVILGDVMEIRKRNRK-----VAEIPFNST-NKFQLSIHEMDDPHGKRFLMVMKGA 525
Query: 655 PEAIAGLCKP-----ETVPVD------FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQ 703
PE I C E P+D F + G RV+ H L + + +
Sbjct: 526 PERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPAD-EFPETY 584
Query: 704 NISRDAIE---NNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVAR 760
+ DA+ +N+ F+GL+ M + + P + A I+ +MVTGD +TA ++A+
Sbjct: 585 SFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAK 644
Query: 761 DCGMILPQDKVI--IAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSL 818
G+I + + IA L + V ++N +A + L
Sbjct: 645 SVGIISANSETVEDIAHRL---NIAVEQVN----------------KRDAKAAVVTGMEL 685
Query: 819 EDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFV 878
+D M+ + IL ++Q++ VFAR +P QK ++E Q D V
Sbjct: 686 KD---------MSSEQLDEILANYQEI---------VFARTSPQQKLIIVEGCQRQDAVV 727
Query: 879 GMCGDGANDCGALKRAHGGISL---SELEASVASPFTSKTPSISCVPNLIREGRAALITS 935
+ GDG ND ALK+A GI++ A A+ + + + + EGR
Sbjct: 728 AVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLI---- 783
Query: 936 FCVFKFMALYSIIQY------FSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAW 989
F K YS+ + F + ++ + +G LFIDL ++ ++ A
Sbjct: 784 FDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAE 843
Query: 990 KELVAQRP 997
+++ ++P
Sbjct: 844 SDIMNRKP 851
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 112 bits (281), Expect = 2e-24
Identities = 188/857 (21%), Positives = 339/857 (39%), Gaps = 132/857 (15%)
Query: 217 IFQLFSVILWSTDEYYYYALAI----------------VVMSIVSIVSSLYSIRKQYVML 260
+F FS++LW + A I VV++ V IV+ +S ++
Sbjct: 94 LFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSS 153
Query: 261 HDMVATHSTVRVSVCRVNE-EIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGT-CIVN 318
M + + V + E E +I + ++V GD++ + G +P D +I+ C V+
Sbjct: 154 KIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVK-GGDRVPADLRIISSHGCKVD 212
Query: 319 ESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKA 378
S LTGES P T++ + + R+ F T ++ +
Sbjct: 213 NSSLTGESEPQTRSP------------EFTHENPLETRNICFFSTNCVEGT------ARG 254
Query: 379 IVVRTGFSTSKGQL--VRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNE 436
IV+ TG T G++ + S L T + + ++ L+ VAV +G + +++ IL
Sbjct: 255 IVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVF-LGVSFFVLSLILGY 313
Query: 437 VQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVC 496
+ +I + II VP L A +T + +R+ + + + + G + +C
Sbjct: 314 SWLEAVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTIC 372
Query: 497 FDKTGTLTEDGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEG 553
DKTGTLT++ + +W ++ A + + F T +L++I G
Sbjct: 373 SDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSG--------ATFDKRSPTWTALSRIAG 424
Query: 554 VLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEMELFE 613
+ + + +A +E ++ R L G+
Sbjct: 425 LCNR-------------AVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDR 471
Query: 614 LPATYEIGIVRQFPFSSALQ-RMSVVARVLGDRKMDAYMKGAPEAIAGLCKP-----ETV 667
P EI PF+S + ++S+ R + MKGAPE I C + +
Sbjct: 472 NPKVAEI------PFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEI 525
Query: 668 PVD------FQNVLEDFTKQGFRVIALAHRKLESKL--TWHKVQNISRDAIENNMDFMGL 719
P+D FQN + G RV+ L S K + + F+GL
Sbjct: 526 PLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGL 585
Query: 720 IIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPP 779
+ M + + P + A I+ +MVTGD +TA ++A+ G II+E
Sbjct: 586 MSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IISEGNET 637
Query: 780 KDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVIL 839
+ A++N S ++P +VH S DL+ M + IL
Sbjct: 638 VEDIAARLNIPM----------SQVNPREAKACVVHGS--DLK------DMTSEQLDEIL 679
Query: 840 EHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGIS 899
++ ++V FAR +P QK ++E Q V + GDG ND ALK+A GI+
Sbjct: 680 KNHTEIV---------FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIA 730
Query: 900 LSELEASV---ASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFKFMALYSIIQYFSVT 954
+ + V A+ + + + + EGR + + + I F +
Sbjct: 731 MGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLF 790
Query: 955 LLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSG----LISGALLFSV 1010
++ +I LG L IDL +V +++ A +++ ++P + L++ L+
Sbjct: 791 IIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMA 850
Query: 1011 LSQIIICIGFQSLGFFW 1027
QI + Q+LG F+
Sbjct: 851 YGQIGM---IQALGGFF 864
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 110 bits (274), Expect = 1e-23
Identities = 180/795 (22%), Positives = 305/795 (38%), Gaps = 152/795 (19%)
Query: 279 EEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLIN---GTCIVNESMLTGESVPVTKTNLP 335
+ ++ I + D+VPGD++ I + G +P D L + T V++S+LTGESV V K P
Sbjct: 135 KSVQRIKAKDIVPGDIVEIAV-GDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDP 193
Query: 336 NPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQL--- 392
P D + + + K++ LF GT + + +VV TG +T G++
Sbjct: 194 VP--DPRAVNQD-------KKNMLFSGTNIAAGK------AMGVVVATGVNTEIGKIRDE 238
Query: 393 ------VRSILYPKPTDFKLYRDAYLFLLCL-VAVAGIGFIYTIINS---ILNEVQVGVI 442
R+ L K +F + L+C+ V + IG ++ I + I
Sbjct: 239 MVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKI 298
Query: 443 IIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGT 502
+ + +P LPA +T + RR+ K S + G +++C DKTGT
Sbjct: 299 AVA---LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355
Query: 503 LTEDGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCH------------- 546
LT + + ++ + RVE + NE + A + H
Sbjct: 356 LTTNQMSVCRMFILDRVEG------DTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDG 409
Query: 547 --SLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQL--LPEST 602
L I + + LD + + + EATE M K L + +
Sbjct: 410 LVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERAN 469
Query: 603 PAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVA---RVLGDRKMDAYMKGAPEAIA 659
+ +L + T E FS + MSV + ++KGAPE +
Sbjct: 470 ACNSVIKQLMKKEFTLE--------FSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVI 521
Query: 660 GLCK---------PETVPVDFQNVLEDFTKQG-----FRVIALA-HRKLESKLTWHKVQN 704
C P T V Q ++ + G R +ALA H + H +
Sbjct: 522 DRCTHIRVGSTKVPMTSGVK-QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDS 580
Query: 705 ISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGM 764
+ E N+ F+G + M + + E + ++ +A IR +M+TGD+ TAV++ R G
Sbjct: 581 ANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIG- 639
Query: 765 ILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMT 824
I QD+ + ++A ++ D L +PSA
Sbjct: 640 IFGQDEDVTSKAFTGRE----------FDEL----NPSA--------------------- 664
Query: 825 RYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDG 884
+ +N + F+ R+ P K++++E LQ+ D M GDG
Sbjct: 665 QRDACLNARCFA---------------------RVEPSHKSKIVEFLQSFDEITAMTGDG 703
Query: 885 ANDCGALKRAHGGISLSE--LEASVASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFK 940
ND ALK+A GI++ A AS + S + + EGRA + F +
Sbjct: 704 VNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYL 763
Query: 941 FMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELV---AQRP 997
+ + +T L Q L+++L + + NP +++ + P
Sbjct: 764 ISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNP 823
Query: 998 PSGLISGALLFSVLS 1012
LISG L F L+
Sbjct: 824 KEPLISGWLFFRYLA 838
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
sapiens]
Length = 1042
Score = 110 bits (274), Expect = 1e-23
Identities = 180/795 (22%), Positives = 305/795 (38%), Gaps = 152/795 (19%)
Query: 279 EEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLIN---GTCIVNESMLTGESVPVTKTNLP 335
+ ++ I + D+VPGD++ I + G +P D L + T V++S+LTGESV V K P
Sbjct: 135 KSVQRIKAKDIVPGDIVEIAV-GDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDP 193
Query: 336 NPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQL--- 392
P D + + + K++ LF GT + + +VV TG +T G++
Sbjct: 194 VP--DPRAVNQD-------KKNMLFSGTNIAAGK------AMGVVVATGVNTEIGKIRDE 238
Query: 393 ------VRSILYPKPTDFKLYRDAYLFLLCL-VAVAGIGFIYTIINS---ILNEVQVGVI 442
R+ L K +F + L+C+ V + IG ++ I + I
Sbjct: 239 MVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKI 298
Query: 443 IIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGT 502
+ + +P LPA +T + RR+ K S + G +++C DKTGT
Sbjct: 299 AVA---LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355
Query: 503 LTEDGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCH------------- 546
LT + + ++ + RVE + NE + A + H
Sbjct: 356 LTTNQMSVCRMFILDRVEG------DTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDG 409
Query: 547 --SLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQL--LPEST 602
L I + + LD + + + EATE M K L + +
Sbjct: 410 LVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERAN 469
Query: 603 PAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVA---RVLGDRKMDAYMKGAPEAIA 659
+ +L + T E FS + MSV + ++KGAPE +
Sbjct: 470 ACNSVIKQLMKKEFTLE--------FSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVI 521
Query: 660 GLCK---------PETVPVDFQNVLEDFTKQG-----FRVIALA-HRKLESKLTWHKVQN 704
C P T V Q ++ + G R +ALA H + H +
Sbjct: 522 DRCTHIRVGSTKVPMTSGVK-QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDS 580
Query: 705 ISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGM 764
+ E N+ F+G + M + + E + ++ +A IR +M+TGD+ TAV++ R G
Sbjct: 581 ANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIG- 639
Query: 765 ILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMT 824
I QD+ + ++A ++ D L +PSA
Sbjct: 640 IFGQDEDVTSKAFTGRE----------FDEL----NPSA--------------------- 664
Query: 825 RYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDG 884
+ +N + F+ R+ P K++++E LQ+ D M GDG
Sbjct: 665 QRDACLNARCFA---------------------RVEPSHKSKIVEFLQSFDEITAMTGDG 703
Query: 885 ANDCGALKRAHGGISLSE--LEASVASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFK 940
ND ALK+A GI++ A AS + S + + EGRA + F +
Sbjct: 704 VNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYL 763
Query: 941 FMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELV---AQRP 997
+ + +T L Q L+++L + + NP +++ + P
Sbjct: 764 ISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNP 823
Query: 998 PSGLISGALLFSVLS 1012
LISG L F L+
Sbjct: 824 KEPLISGWLFFRYLA 838
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 106 bits (264), Expect = 2e-22
Identities = 193/887 (21%), Positives = 346/887 (39%), Gaps = 165/887 (18%)
Query: 178 GLTKGMHAYRKLLYGVNE-IAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYAL 236
GL++ R+L +G NE +A V+K + + NP + L S ++ + Y A+
Sbjct: 76 GLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALVSVLTKEYEDAV 135
Query: 237 AIVVMSIVSIVSSL---YSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGD 293
+I +V + + Y K L MV C +++ + + +LVPGD
Sbjct: 136 SIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPECN-----CLREGKLQHLLARELVPGD 190
Query: 294 VMVIPLNGTIMPCDAVLINGT-CIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPE 352
V+ + + G +P D L T +V+ES TGE+ P +KT+ P + G GD
Sbjct: 191 VVSLSI-GDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSP-----LTGGGDL----- 239
Query: 353 THKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYR--DA 410
T + +F GT V R + +V+ TG S+ G++ + + + L + D
Sbjct: 240 TTLSNIVFMGTLVQYGRG------QGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDR 293
Query: 411 YLFLLCLVAVAGIGFIYTIINS----ILNEVQVGVIIIESLDIITITVPPALPAAMTAGI 466
L L + IG I I S +L+ +GV + +P LP + +
Sbjct: 294 LGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGV------SLAVAAIPEGLPIVVMVTL 347
Query: 467 VYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEE 526
V R+ K + + G +++C DKTGTLT + + + + + R
Sbjct: 348 VLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLR------ 401
Query: 527 NVCNEMLVKSQFVACMATCHSLTK-IEGVLSGDPLDLKMFEAIGWILEEATEEETALHNR 585
+ + Q C+ + K V G K+ EA G + A + A+ +
Sbjct: 402 AEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVG-----KLVEA-GCVANNAVIRKNAVMGQ 455
Query: 586 IMPTVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDR 645
PT + A +M+L ++ +Y ++ PFSS + M+V + +
Sbjct: 456 --PT---------EGALMALAMKMDLSDIKNSYI--RKKEIPFSSEQKWMAVKCSLKTED 502
Query: 646 KMDAY-MKGAPEAIAGLCKPET---VPVDFQNVLEDFTKQ--------GFRVIALAHRKL 693
+ D Y MKGA E + C +P+ F Q G RV+ALA
Sbjct: 503 QEDIYFMKGALEEVIRYCTMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGPE 562
Query: 694 ESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSML 753
+LT F+GL+ + + + ++ L ++ + M+TGD++
Sbjct: 563 LGRLT-----------------FLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALE 605
Query: 754 TAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKL 813
TA+++ R+ G+ +GK+ ++ DS+ + + ++
Sbjct: 606 TALAIGRNIGLC---------------NGKLQAMSGEEVDSVEKGELADRVGKVSV---- 646
Query: 814 VHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQN 873
F +H ++ L G + A
Sbjct: 647 --------------------FFRTSPKHKLKIIKALQESGAIVA---------------- 670
Query: 874 VDYFVGMCGDGANDCGALKRAHGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRA 930
M GDG ND ALK A GI++ + V A+ S + N + EG+
Sbjct: 671 ------MTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNAVEEGKG 724
Query: 931 AL--ITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPA 988
I +F F+ S + +++ ++++ S L Q L+I++ + ++ + P
Sbjct: 725 IFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLGVEPV 784
Query: 989 WKELVAQRPPS---GLISGALLFSVLSQIIICIGFQSLGFFWVKQQP 1032
K+ Q P S ++S AL+ +L I I +L FW K+ P
Sbjct: 785 DKDAFRQPPRSVRDTILSRALILKILMSAAIIIS-GTLFIFW-KEMP 829
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 105 bits (262), Expect = 3e-22
Identities = 185/856 (21%), Positives = 341/856 (39%), Gaps = 129/856 (15%)
Query: 217 IFQLFSVILWSTDEYYYYALAI----------------VVMSIVSIVSSLYSIRKQYVML 260
+F FS++LW + A I +V++ V I++ +S ++
Sbjct: 86 LFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSS 145
Query: 261 HDMVATHSTVRVSVCRVNE-EIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGT-CIVN 318
M + + V + E E ++ + ++V GD++ I G +P D +I+ C V+
Sbjct: 146 KIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIK-GGDRVPADLRIISAHGCKVD 204
Query: 319 ESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKA 378
S LTGES P T++ P+ + D NP + T F V T +
Sbjct: 205 NSSLTGESEPQTRS--PDCTHD---------NPLETRNITFFSTNCVEGT-------ARG 246
Query: 379 IVVRTGFSTSKGQL--VRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNE 436
+VV TG T G++ + S L T + + ++ L+ VAV +G + I++ IL
Sbjct: 247 VVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVF-LGVSFFILSLILGY 305
Query: 437 VQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVC 496
+ +I + II VP L A +T + +R+ + + + + G + +C
Sbjct: 306 TWLEAVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTIC 364
Query: 497 FDKTGTLTEDGL---DLWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEG 553
DKTGTLT++ + +W ++ A + + F T +L+ I G
Sbjct: 365 SDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSG--------TSFDKSSHTWVALSHIAG 416
Query: 554 VLS-------GDPLDLKMFEAIGWILEEATEEETALHN---RIMPTVVRPPKQLLPESTP 603
+ + D + + + G E A + L + ++M + ++ ST
Sbjct: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTN 476
Query: 604 AGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCK 663
+ E P +V + L R S + ++ +D MK A
Sbjct: 477 KYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEA--------- 527
Query: 664 PETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIE---NNMDFMGLI 720
FQN + G RV+ H L + + K D + +N+ F+GL+
Sbjct: 528 -------FQNAYLELGGLGERVLGFCHYYLPEE-QFPKGFAFDCDDVNFTTDNLCFVGLM 579
Query: 721 IMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPK 780
M + + P + A I+ +MVTGD +TA ++A+ G II+E
Sbjct: 580 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IISEGNETV 631
Query: 781 DGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILE 840
+ A++N S ++P ++H + DL+ + IL+
Sbjct: 632 EDIAARLN----------IPVSQVNPRDAKACVIHGT--DLK------DFTSEQIDEILQ 673
Query: 841 HFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISL 900
+ ++ VFAR +P QK ++E Q V + GDG ND ALK+A G+++
Sbjct: 674 NHTEI---------VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAM 724
Query: 901 SELEASV---ASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFKFMALYSIIQYFSVTL 955
+ V A+ + + + + EGR + + + I F + +
Sbjct: 725 GIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFI 784
Query: 956 LYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRP----PSGLISGALLFSVL 1011
+ +I LG L IDL +V +++ A +++ ++P L++ L+
Sbjct: 785 MANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAY 844
Query: 1012 SQIIICIGFQSLGFFW 1027
QI + Q+LG F+
Sbjct: 845 GQIGM---IQALGGFF 857
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
Length = 939
Score = 104 bits (259), Expect = 6e-22
Identities = 192/883 (21%), Positives = 333/883 (37%), Gaps = 165/883 (18%)
Query: 178 GLTKGMHAYRKLLYGVNEIAVKVPS-VFKLLIKEVLNPFYIFQL----FSVILWSTDEYY 232
GL K ++R+ +G NE + ++K I + NP + L SV++ D+
Sbjct: 45 GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAV 104
Query: 233 YYALAIVVMSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPG 292
+AI+++ V+ V Y K L +V C ++E + DLVPG
Sbjct: 105 SITVAILIVVTVAFVQE-YRSEKSLEELSKLVPPECH-----CVREGKLEHTLARDLVPG 158
Query: 293 DVMVIPLNGTIMPCDAVLINGTCI-VNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNP 351
D + + + G +P D L + ++ES LTGE+ P +K P P+ +
Sbjct: 159 DTVCLSV-GDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLAS----- 212
Query: 352 ETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAY 411
+ + F GT V + K +V+ TG ++ G++ + + + L +
Sbjct: 213 ---RSNIAFMGTLVRCGK------AKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 412 LFLLCLVAVA-GIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQ 470
L L + GI I ++ +L + + + I S+ + +P LP +T +
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTI-SVSLAVAAIPEGLPIVVTVTLALGV 322
Query: 471 RRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVE--NARFLSPEENV 528
R+ K + G N++C DKTGTLT++ + + I + +A N
Sbjct: 323 MRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQ 382
Query: 529 CNEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMP 588
E++V V H +P ++ EA G + +A L + P
Sbjct: 383 FGEVIVDGDVV------HGFY--------NPAVSRIVEA-GCVCNDAVIRNNTLMGK--P 425
Query: 589 TVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVR--QFPFSSALQRMSV--VARVLGD 644
T + A +M L L Y +R ++PFSS + M+V V R D
Sbjct: 426 T---------EGALIALAMKMGLDGLQQDY----IRKAEYPFSSEQKWMAVKCVHRTQQD 472
Query: 645 RKMDAYMKGAPEAIAGLC-----KPETVPVD------FQNVLEDFTKQGFRVIALAHRKL 693
R +MKGA E + C K +T+ + +Q G RV+ALA
Sbjct: 473 RPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPE 532
Query: 694 ESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSML 753
+LT F+GL+ + + + + L + + M+TGDS
Sbjct: 533 LGQLT-----------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQE 575
Query: 754 TAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKL 813
TAV++A G+ + + E + D L+Q A+ A P
Sbjct: 576 TAVAIASRLGLYSKTSQSVSGEEIDAMD----------VQQLSQIVPKVAVFYRASP--- 622
Query: 814 VHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQN 873
H ++ L +G+V
Sbjct: 623 --------------------------RHKMKIIKSLQKNGSV------------------ 638
Query: 874 VDYFVGMCGDGANDCGALKRAHGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRA 930
V M GDG ND ALK A G+++ + V A+ + + I EG+
Sbjct: 639 ----VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKG 694
Query: 931 AL--ITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPA 988
I +F F+ + + S+ L + + L Q L+I++ + ++ + P
Sbjct: 695 IYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPV 754
Query: 989 WKELVAQRP----PSGLISGALLFSVLSQIIICIGFQSLGFFW 1027
K+++ + P S L +L ++S III G +L FW
Sbjct: 755 DKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCG--TLFVFW 795
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
Length = 949
Score = 104 bits (259), Expect = 6e-22
Identities = 192/883 (21%), Positives = 333/883 (37%), Gaps = 165/883 (18%)
Query: 178 GLTKGMHAYRKLLYGVNEIAVKVPS-VFKLLIKEVLNPFYIFQL----FSVILWSTDEYY 232
GL K ++R+ +G NE + ++K I + NP + L SV++ D+
Sbjct: 45 GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAV 104
Query: 233 YYALAIVVMSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPG 292
+AI+++ V+ V Y K L +V C ++E + DLVPG
Sbjct: 105 SITVAILIVVTVAFVQE-YRSEKSLEELSKLVPPECH-----CVREGKLEHTLARDLVPG 158
Query: 293 DVMVIPLNGTIMPCDAVLINGTCI-VNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNP 351
D + + + G +P D L + ++ES LTGE+ P +K P P+ +
Sbjct: 159 DTVCLSV-GDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLAS----- 212
Query: 352 ETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAY 411
+ + F GT V + K +V+ TG ++ G++ + + + L +
Sbjct: 213 ---RSNIAFMGTLVRCGK------AKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 412 LFLLCLVAVA-GIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQ 470
L L + GI I ++ +L + + + I S+ + +P LP +T +
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTI-SVSLAVAAIPEGLPIVVTVTLALGV 322
Query: 471 RRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVE--NARFLSPEENV 528
R+ K + G N++C DKTGTLT++ + + I + +A N
Sbjct: 323 MRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQ 382
Query: 529 CNEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMP 588
E++V V H +P ++ EA G + +A L + P
Sbjct: 383 FGEVIVDGDVV------HGFY--------NPAVSRIVEA-GCVCNDAVIRNNTLMGK--P 425
Query: 589 TVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVR--QFPFSSALQRMSV--VARVLGD 644
T + A +M L L Y +R ++PFSS + M+V V R D
Sbjct: 426 T---------EGALIALAMKMGLDGLQQDY----IRKAEYPFSSEQKWMAVKCVHRTQQD 472
Query: 645 RKMDAYMKGAPEAIAGLC-----KPETVPVD------FQNVLEDFTKQGFRVIALAHRKL 693
R +MKGA E + C K +T+ + +Q G RV+ALA
Sbjct: 473 RPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPE 532
Query: 694 ESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSML 753
+LT F+GL+ + + + + L + + M+TGDS
Sbjct: 533 LGQLT-----------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQE 575
Query: 754 TAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKL 813
TAV++A G+ + + E + D L+Q A+ A P
Sbjct: 576 TAVAIASRLGLYSKTSQSVSGEEIDAMD----------VQQLSQIVPKVAVFYRASP--- 622
Query: 814 VHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQN 873
H ++ L +G+V
Sbjct: 623 --------------------------RHKMKIIKSLQKNGSV------------------ 638
Query: 874 VDYFVGMCGDGANDCGALKRAHGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRA 930
V M GDG ND ALK A G+++ + V A+ + + I EG+
Sbjct: 639 ----VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKG 694
Query: 931 AL--ITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPA 988
I +F F+ + + S+ L + + L Q L+I++ + ++ + P
Sbjct: 695 IYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPV 754
Query: 989 WKELVAQRP----PSGLISGALLFSVLSQIIICIGFQSLGFFW 1027
K+++ + P S L +L ++S III G +L FW
Sbjct: 755 DKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCG--TLFVFW 795
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
Length = 888
Score = 104 bits (259), Expect = 6e-22
Identities = 192/883 (21%), Positives = 333/883 (37%), Gaps = 165/883 (18%)
Query: 178 GLTKGMHAYRKLLYGVNEIAVKVPS-VFKLLIKEVLNPFYIFQL----FSVILWSTDEYY 232
GL K ++R+ +G NE + ++K I + NP + L SV++ D+
Sbjct: 45 GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAV 104
Query: 233 YYALAIVVMSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPG 292
+AI+++ V+ V Y K L +V C ++E + DLVPG
Sbjct: 105 SITVAILIVVTVAFVQE-YRSEKSLEELSKLVPPECH-----CVREGKLEHTLARDLVPG 158
Query: 293 DVMVIPLNGTIMPCDAVLINGTCI-VNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNP 351
D + + + G +P D L + ++ES LTGE+ P +K P P+ +
Sbjct: 159 DTVCLSV-GDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLAS----- 212
Query: 352 ETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAY 411
+ + F GT V + K +V+ TG ++ G++ + + + L +
Sbjct: 213 ---RSNIAFMGTLVRCGK------AKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 412 LFLLCLVAVA-GIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQ 470
L L + GI I ++ +L + + + I S+ + +P LP +T +
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTI-SVSLAVAAIPEGLPIVVTVTLALGV 322
Query: 471 RRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVE--NARFLSPEENV 528
R+ K + G N++C DKTGTLT++ + + I + +A N
Sbjct: 323 MRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQ 382
Query: 529 CNEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMP 588
E++V V H +P ++ EA G + +A L + P
Sbjct: 383 FGEVIVDGDVV------HGFY--------NPAVSRIVEA-GCVCNDAVIRNNTLMGK--P 425
Query: 589 TVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVR--QFPFSSALQRMSV--VARVLGD 644
T + A +M L L Y +R ++PFSS + M+V V R D
Sbjct: 426 T---------EGALIALAMKMGLDGLQQDY----IRKAEYPFSSEQKWMAVKCVHRTQQD 472
Query: 645 RKMDAYMKGAPEAIAGLC-----KPETVPVD------FQNVLEDFTKQGFRVIALAHRKL 693
R +MKGA E + C K +T+ + +Q G RV+ALA
Sbjct: 473 RPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPE 532
Query: 694 ESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSML 753
+LT F+GL+ + + + + L + + M+TGDS
Sbjct: 533 LGQLT-----------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQE 575
Query: 754 TAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKL 813
TAV++A G+ + + E + D L+Q A+ A P
Sbjct: 576 TAVAIASRLGLYSKTSQSVSGEEIDAMD----------VQQLSQIVPKVAVFYRASP--- 622
Query: 814 VHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQN 873
H ++ L +G+V
Sbjct: 623 --------------------------RHKMKIIKSLQKNGSV------------------ 638
Query: 874 VDYFVGMCGDGANDCGALKRAHGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRA 930
V M GDG ND ALK A G+++ + V A+ + + I EG+
Sbjct: 639 ----VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKG 694
Query: 931 AL--ITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPA 988
I +F F+ + + S+ L + + L Q L+I++ + ++ + P
Sbjct: 695 IYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPV 754
Query: 989 WKELVAQRP----PSGLISGALLFSVLSQIIICIGFQSLGFFW 1027
K+++ + P S L +L ++S III G +L FW
Sbjct: 755 DKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCG--TLFVFW 795
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
Length = 919
Score = 104 bits (259), Expect = 6e-22
Identities = 192/883 (21%), Positives = 333/883 (37%), Gaps = 165/883 (18%)
Query: 178 GLTKGMHAYRKLLYGVNEIAVKVPS-VFKLLIKEVLNPFYIFQL----FSVILWSTDEYY 232
GL K ++R+ +G NE + ++K I + NP + L SV++ D+
Sbjct: 45 GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAV 104
Query: 233 YYALAIVVMSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPG 292
+AI+++ V+ V Y K L +V C ++E + DLVPG
Sbjct: 105 SITVAILIVVTVAFVQE-YRSEKSLEELSKLVPPECH-----CVREGKLEHTLARDLVPG 158
Query: 293 DVMVIPLNGTIMPCDAVLINGTCI-VNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNP 351
D + + + G +P D L + ++ES LTGE+ P +K P P+ +
Sbjct: 159 DTVCLSV-GDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLAS----- 212
Query: 352 ETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAY 411
+ + F GT V + K +V+ TG ++ G++ + + + L +
Sbjct: 213 ---RSNIAFMGTLVRCGK------AKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 412 LFLLCLVAVA-GIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQ 470
L L + GI I ++ +L + + + I S+ + +P LP +T +
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTI-SVSLAVAAIPEGLPIVVTVTLALGV 322
Query: 471 RRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVE--NARFLSPEENV 528
R+ K + G N++C DKTGTLT++ + + I + +A N
Sbjct: 323 MRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQ 382
Query: 529 CNEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMP 588
E++V V H +P ++ EA G + +A L + P
Sbjct: 383 FGEVIVDGDVV------HGFY--------NPAVSRIVEA-GCVCNDAVIRNNTLMGK--P 425
Query: 589 TVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVR--QFPFSSALQRMSV--VARVLGD 644
T + A +M L L Y +R ++PFSS + M+V V R D
Sbjct: 426 T---------EGALIALAMKMGLDGLQQDY----IRKAEYPFSSEQKWMAVKCVHRTQQD 472
Query: 645 RKMDAYMKGAPEAIAGLC-----KPETVPVD------FQNVLEDFTKQGFRVIALAHRKL 693
R +MKGA E + C K +T+ + +Q G RV+ALA
Sbjct: 473 RPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPE 532
Query: 694 ESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSML 753
+LT F+GL+ + + + + L + + M+TGDS
Sbjct: 533 LGQLT-----------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQE 575
Query: 754 TAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKL 813
TAV++A G+ + + E + D L+Q A+ A P
Sbjct: 576 TAVAIASRLGLYSKTSQSVSGEEIDAMD----------VQQLSQIVPKVAVFYRASP--- 622
Query: 814 VHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQN 873
H ++ L +G+V
Sbjct: 623 --------------------------RHKMKIIKSLQKNGSV------------------ 638
Query: 874 VDYFVGMCGDGANDCGALKRAHGGISLSELEASV---ASPFTSKTPSISCVPNLIREGRA 930
V M GDG ND ALK A G+++ + V A+ + + I EG+
Sbjct: 639 ----VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKG 694
Query: 931 AL--ITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPA 988
I +F F+ + + S+ L + + L Q L+I++ + ++ + P
Sbjct: 695 IYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPV 754
Query: 989 WKELVAQRP----PSGLISGALLFSVLSQIIICIGFQSLGFFW 1027
K+++ + P S L +L ++S III G +L FW
Sbjct: 755 DKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCG--TLFVFW 795
>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
Length = 1035
Score = 95.5 bits (236), Expect = 3e-19
Identities = 203/996 (20%), Positives = 377/996 (37%), Gaps = 155/996 (15%)
Query: 227 STDEYYYYALAIVVMSIVSIVSSLYSIRKQYVMLHDMVATHSTV--RVSVCRVNEEIEEI 284
+TD+ Y A+A++ V +V+ + +++ + + + + V + +V R ++ + I
Sbjct: 136 TTDDNLYLAIALIA---VVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQ-I 191
Query: 285 FSTDLVPGDVMVIPLNGTIMPCDA-VLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKG 343
+ LV GD++ + G +P D +L C V+ S LTGES P T++
Sbjct: 192 NADQLVVGDLVEMK-GGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSP---------- 240
Query: 344 IGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQL--VRSILYPKP 401
+ + R+ F T ++ V+ +VV TG T G++ + S + +
Sbjct: 241 --ECTHESPLETRNIAFFSTMCLEGT------VQGLVVNTGDRTIIGRIASLASGVENEK 292
Query: 402 TDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAA 461
T + + ++ ++ +A+ G + I+ + + ++ + I+ VP L A
Sbjct: 293 TPIAIEIEHFVDIIAGLAIL-FGATFFIVAMCIGYTFLRAMVF-FMAIVVAYVPEGLLAT 350
Query: 462 MTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGL---DLWGIQRVEN 518
+T + +RL + + + G +++C DKTGTLT++ + LW +
Sbjct: 351 VTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHT 410
Query: 519 ARFLSPEENVCNEMLVKSQFVAC--MATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEAT 576
A + + ++ C + C+ G D + + IG
Sbjct: 411 ADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSG---QDAVPVPKRIVIG------D 461
Query: 577 EEETALHNRIMPTVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMS 636
ETAL L GN P EI PF+S +
Sbjct: 462 ASETAL--------------LKFSELTLGNAMGYRDRFPKVCEI------PFNST-NKFQ 500
Query: 637 VVARVLGDRKMDAY---MKGAPEAIAGLC-----KPETVPVD------FQNVLEDFTKQG 682
+ L D + + MKGAPE + C K + +P+D FQ G
Sbjct: 501 LSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLG 560
Query: 683 FRVIALAHRKLESK--LTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKA 740
RV+ L K + + + + + F GL+ M + + P + A
Sbjct: 561 ERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTA 620
Query: 741 NIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSH 800
IR +MVTGD +TA ++A G II+E + A++
Sbjct: 621 GIRVIMVTGDHPITAKAIAASVG--------IISEGSETVEDIAARLR------------ 660
Query: 801 PSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLH-GTVFARM 859
+PV V+ + +NG + +LV L H VFAR
Sbjct: 661 --------VPVDQVN------RKDARACVINGMQLKDM--DPSELVEALRTHPEMVFART 704
Query: 860 APDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISL---SELEASVASPFTSKTP 916
+P QK ++E+ Q + V + GDG ND ALK+A G+++ A A+
Sbjct: 705 SPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDD 764
Query: 917 SISCVPNLIREGRAAL--ITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLA 974
+ + + + +GR + + + + + + S+ LG LFI+L
Sbjct: 765 NFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELC 824
Query: 975 IILVVVFTMSLNPAWKELVAQRPPS----GLIS---GALLFSVLSQIIICIGFQSLGFFW 1027
+ +++ A +++ RP + L++ A + + I GF F
Sbjct: 825 TDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDY-FTA 883
Query: 1028 VKQQPWYEVWHPKSDACNTTGSGFWNSSHVDN-------ETELDEHNIQNYENTTVFFIS 1080
+ Q+ W+ + A W H+ + E + Q Y TVFFIS
Sbjct: 884 MAQEGWFPLLCVGLRA-------QWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFIS 936
Query: 1081 SFQYLIVAIAFSKGK---PFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVC 1137
I + K + F+Q ++N V +++F F+ P + + +
Sbjct: 937 IEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCP--GMPNIFNFMP 994
Query: 1138 VPYQWRVTMLIIVLVNAFVSITVEESVDRWGKCCLP 1173
+ +QW + L ++ I V + + + G C P
Sbjct: 995 IRFQWWLVPLPYGIL-----IFVYDEIRKLGVRCCP 1025
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
sapiens]
Length = 1015
Score = 92.4 bits (228), Expect = 2e-18
Identities = 171/792 (21%), Positives = 290/792 (36%), Gaps = 173/792 (21%)
Query: 279 EEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPS 338
+ ++ I + D+VPGD++ I GESV V K P P
Sbjct: 135 KSVQRIKAKDIVPGDIVEI-------------------------AGESVSVIKHTDPVP- 168
Query: 339 VDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQL------ 392
D + + + K++ LF GT + + +VV TG +T G++
Sbjct: 169 -DPRAVNQD-------KKNMLFSGTNIAAGK------AMGVVVATGVNTEIGKIRDEMVA 214
Query: 393 ---VRSILYPKPTDFKLYRDAYLFLLCL-VAVAGIGFIYTIINS---ILNEVQVGVIIIE 445
R+ L K +F + L+C+ V + IG ++ I + I +
Sbjct: 215 TEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVA 274
Query: 446 SLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTE 505
+ +P LPA +T + RR+ K S + G +++C DKTGTLT
Sbjct: 275 ---LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTT 331
Query: 506 DGLD---LWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCH---------------S 547
+ + ++ + RVE + NE + A + H
Sbjct: 332 NQMSVCRMFILDRVEG------DTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVE 385
Query: 548 LTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQL--LPESTPAG 605
L I + + LD + + + EATE M K L + +
Sbjct: 386 LATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACN 445
Query: 606 NQEMELFELPATYEIGIVRQFPFSSALQRMSVVA---RVLGDRKMDAYMKGAPEAIAGLC 662
+ +L + T E FS + MSV + ++KGAPE + C
Sbjct: 446 SVIKQLMKKEFTLE--------FSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRC 497
Query: 663 K---------PETVPVDFQNVLEDFTKQG-----FRVIALA-HRKLESKLTWHKVQNISR 707
P T V Q ++ + G R +ALA H + H + +
Sbjct: 498 THIRVGSTKVPMTSGVK-QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANF 556
Query: 708 DAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILP 767
E N+ F+G + M + + E + ++ +A IR +M+TGD+ TAV++ R G I
Sbjct: 557 IKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIG-IFG 615
Query: 768 QDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYH 827
QD+ + ++A ++ D L +PSA +
Sbjct: 616 QDEDVTSKAFTGRE----------FDEL----NPSA---------------------QRD 640
Query: 828 FAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGAND 887
+N + F+ R+ P K++++E LQ+ D M GDG ND
Sbjct: 641 ACLNARCFA---------------------RVEPSHKSKIVEFLQSFDEITAMTGDGVND 679
Query: 888 CGALKRAHGGISLSE--LEASVASPFTSKTPSISCVPNLIREGRAAL--ITSFCVFKFMA 943
ALK+A GI++ A AS + S + + EGRA + F + +
Sbjct: 680 APALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISS 739
Query: 944 LYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELV---AQRPPSG 1000
+ +T L Q L+++L + + NP +++ + P
Sbjct: 740 NVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEP 799
Query: 1001 LISGALLFSVLS 1012
LISG L F L+
Sbjct: 800 LISGWLFFRYLA 811
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 88.2 bits (217), Expect = 4e-17
Identities = 138/595 (23%), Positives = 243/595 (40%), Gaps = 110/595 (18%)
Query: 490 GQLNLVCFDKTGTLTEDGLD-----LWGIQRVENARFLSPEENVCNEMLVKS-------- 536
GQ+ + DKTGTLT + + + G+ +N++F E+ + L+++
Sbjct: 401 GQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQF-GDEKTFSDSSLLENLQNNHPTA 459
Query: 537 ----QFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVR 592
+F+ MA CH+ GD + I + A+ +E AL VR
Sbjct: 460 PIICEFLTMMAVCHTAVPER---EGDKI----------IYQAASPDEGAL--------VR 498
Query: 593 PPKQLLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMK 652
KQL T + + L ++ F+SA +RMSV+ R K+ Y K
Sbjct: 499 AAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSG-KLRLYCK 557
Query: 653 GAPEAIAG-LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESK--LTWH--------K 701
GA I L + LE F +G R + A ++ W
Sbjct: 558 GADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTS 617
Query: 702 VQNI------SRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTA 755
VQN S + IE N+ +G +++KL+ + P +E L KA+I+ ++TGD TA
Sbjct: 618 VQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETA 677
Query: 756 VSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVH 815
+++ C ++ +I+ DG ++ H C+
Sbjct: 678 INIGHSCKLLKKNMGMIVINE-GSLDGTRETLSRH-------CT---------------- 713
Query: 816 DSLEDLQMTRYHFAM--NGKSFSVIL-----EHFQDLVPKLMLHGTVFARMAPDQKTQLI 868
+L D FA+ +GK+ L ++F DL L + R++P QK++++
Sbjct: 714 -TLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLA--LSCKAVICCRVSPLQKSEVV 770
Query: 869 EALQNVDYFVGMC-GDGANDCGALKRAHGGISLS---ELEASVASPFT----SKTPSISC 920
E ++ V + GDGAND ++ AH G+ +S L+A+ +S ++ ++
Sbjct: 771 EMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLM 830
Query: 921 VPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYS--ILSN---LGDFQFLFIDLAI 975
+ R + +C +K + LY I +F+ +S IL +G + +F +
Sbjct: 831 IHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPP 890
Query: 976 ILVVVFTMSLNPAWKELVAQRPPSGLIS-GALLFSVLSQIIICIG--FQSLGFFW 1027
+ + +F S KE + + P S AL F+ + C+ F S+ FW
Sbjct: 891 LTLGIFERSCR---KENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFW 942
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 86.3 bits (212), Expect = 2e-16
Identities = 204/957 (21%), Positives = 372/957 (38%), Gaps = 191/957 (19%)
Query: 161 GLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPF-YIFQ 219
G E + C E + G R Y N I + + F L + N F Y F
Sbjct: 23 GCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFN 82
Query: 220 LFSVILWSTDE---------YYYYALAIVVMSIVSIVSSLYSIRKQYVM---LHDMVATH 267
L+ ++L + Y Y+ V+++ I ++ IR YV ++ V +
Sbjct: 83 LYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRC-YVRDKEVNSQVYSR 141
Query: 268 STVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLI-----NGTCIVNESML 322
T R +V ++ S+++ GD++++ N + P D + + NG+C + L
Sbjct: 142 LTARGTV--------KVKSSNIQVGDLIIVEKNQRV-PADMIFLRTSEKNGSCFLRTDQL 192
Query: 323 TGES-----VPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTV------------ 365
GE+ +PV T + D+ I +Y E + F GT
Sbjct: 193 DGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESL 252
Query: 366 -IQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLL---CLVAVA 421
I+ + G +V + V G G+ +RS++ K+ LF L CL +
Sbjct: 253 SIENTLWAGTVVASGTV-VGVVLYTGRELRSVMNTSNPRSKIG----LFDLEVNCLTKIL 307
Query: 422 GIGFIYTIINSILNEVQVG---VIIIESLDIITITVPPALPAAMTAG-IVYAQ--RRLKK 475
+ + + + G + II L + + +P +L + G IVY+ RR K
Sbjct: 308 FGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSK 367
Query: 476 I-GIFCISPQRINICGQLNLVCFDKTGTLTED---------GLDLWGIQRVENARF---- 521
I G S G+++ + DKTGTLT++ G +G+ ++ +
Sbjct: 368 IPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFS 427
Query: 522 ------LSPEENVCNEMLVK---------SQFVACMATCHSLTKI---EGVLSGDPLDLK 563
P + K + V +A CH++T + GV + K
Sbjct: 428 IYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAE-K 486
Query: 564 MFEAIGWILEEATEEETAL---HNRIMPTVVRPPKQLLPESTPAGNQEMELFELPATYEI 620
+E + + ++ +E AL + T+V + + TP G+Q +
Sbjct: 487 QYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTP-GDQILNFT-------- 537
Query: 621 GIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVDFQNVLED--- 677
I++ FPF+ +RM ++ R ++ YMKGA +AG+ V + + LE+
Sbjct: 538 -ILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGI-------VQYNDWLEEECG 589
Query: 678 -FTKQGFRVIALAHRKL-------------ESKLTWH----KVQNISRDAIENNMDFMGL 719
++G RV+ +A + L ++KL+ H KV + +++E M+ + L
Sbjct: 590 NMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVI-ESLEMEMELLCL 648
Query: 720 IIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPP 779
++++L+ + LE L A I+ M+TGD + TA A++ ++ + + +
Sbjct: 649 TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTN 708
Query: 780 KDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVIL 839
+ ++N + HD ++G S V L
Sbjct: 709 RGEAHLELN---------------------AFRRKHDCA---------LVISGDSLEVCL 738
Query: 840 EHFQDLVPKLMLH--GTVFARMAPDQKTQLIEALQ-NVDYFVGMCGDGANDCGALKRAHG 896
++++ +L V R AP QK Q++ LQ GDG ND ++ +
Sbjct: 739 KYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDC 798
Query: 897 GISLSELE---ASVASPFT----SKTPSISCVPNLIREGRAALITSF------CVFKFMA 943
G+ + E AS+A+ F+ + V R+A ++ F C+ A
Sbjct: 799 GVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQA 858
Query: 944 LYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVV--VFTMSLNPAWKELVAQRPP 998
++S + YF+ LY FL I + I + VF++ L+ K VA P
Sbjct: 859 VFSSVFYFASVPLYQ--------GFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYP 907
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 83.2 bits (204), Expect = 1e-15
Identities = 89/357 (24%), Positives = 153/357 (42%), Gaps = 53/357 (14%)
Query: 592 RPPKQLLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYM 651
R P+Q++ + G P T+++ + PF S +RMSVV R ++ Y
Sbjct: 747 RTPEQVMVDFAALG---------PLTFQL--LHILPFDSVRKRMSVVVRHPLSNQVVVYT 795
Query: 652 KGAPEAIAGL---CKPETVPVDFQNV---------LEDFTKQGFRVIALAHRKLESK--- 696
KGA I L P+ ++ Q + L+D+ KQG R + +A + +
Sbjct: 796 KGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYA 855
Query: 697 --LTWHKVQNISRD-----------AIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIR 743
L H + S D +EN + +G ++++L++ P +E LHKA I+
Sbjct: 856 EWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIK 915
Query: 744 TVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSA 803
M+TGD TAV++A C ++ P DK+ I KD + L + +
Sbjct: 916 IWMLTGDKQETAVNIAYACKLLEPDDKLFILNT-QSKDA----CGMLMSTILKELQKKTQ 970
Query: 804 IDPEAIPVK--LVHDSLEDLQMTRYHFAMNGKSFSVILEHF---QDLVPKLMLHGTVFAR 858
PE + + L+ + R + GK+ L+ Q L V R
Sbjct: 971 ALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCR 1030
Query: 859 MAPDQKTQLIEALQN-VDYFVGMCGDGANDCGALKRAHGGISLS---ELEASVASPF 911
P QK+++++ +++ + GDGAND ++ A GI +S ++A +AS F
Sbjct: 1031 ATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDF 1087
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 82.8 bits (203), Expect = 2e-15
Identities = 125/530 (23%), Positives = 214/530 (40%), Gaps = 71/530 (13%)
Query: 281 IEEIFSTDLVPGDVMVIPLNGTIMPCDAVLI---NGTCIVNESMLTGESVPVTKTNLPNP 337
++ I + D+VPGD++ + + G +P D LI + T V++S+LTGESV VTK P
Sbjct: 137 VQRIRARDIVPGDIVEVAV-GDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195
Query: 338 SVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSIL 397
D + + + K++ LF GT + +G+ V + V TG T G++ +
Sbjct: 196 --DPRAVNQD-------KKNMLFSGTNIT-----SGKAV-GVAVATGLHTELGKIRSQMA 240
Query: 398 YPKPTDFKLYRDAYLF---LLCLVAVAGIGFIYTIINSILNEVQVGVIIIESLDIITITV 454
+P L R F L ++V + I + G + ++ I V
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300
Query: 455 -------PPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDG 507
P LPA +T + RR+ + S + G +++C DKTGTLT +
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
Query: 508 LD---LWGIQRVENARFLSPEENVC-------NEMLVKSQFVAC--MATCHSLTKIEGVL 555
+ ++ + + L E + E+ Q V C L I +
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420
Query: 556 SGDPLDLKMFEAIGWILEEATEEE-TALHNRIMPTVVRPPKQLLPESTPAGNQEMELFEL 614
+ LD + + + EATE T L ++ V Q L AG + +L
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKM--NVFDTDLQALSRVERAGACNTVIKQL 478
Query: 615 PATYEIGIVRQFPFSSALQRMSVVARVLGDRK------MDAYMKGAPEAIAGLCKPETV- 667
+ ++F + R S+ R ++KGAPE++ C V
Sbjct: 479 -------MRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVG 531
Query: 668 -------PVDFQNVLEDFTKQG-----FRVIALAHRKLESKLTWHKVQNISRDA-IENNM 714
P + +L G R +ALA R + ++ + S+ E ++
Sbjct: 532 SRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDL 591
Query: 715 DFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGM 764
F+G + M + + E A + ++A IR VM+TGD+ TAV++ R G+
Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGI 641
Score = 55.5 bits (132), Expect = 3e-07
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 11/182 (6%)
Query: 842 FQDLVPKLMLHGT----VFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGG 897
F DL P+ FAR+ P K++++E LQ+ + M GDG ND ALK+A G
Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIG 717
Query: 898 ISLSE--LEASVASPFTSKTPSISCVPNLIREGRA--ALITSFCVFKFMALYSIIQYFSV 953
I++ A A+ + + + + EGRA + + F + + + +
Sbjct: 718 IAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
Query: 954 TLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPS---GLISGALLFSV 1010
T + + L Q L+++L + + NP +++ + P S LISG L F
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837
Query: 1011 LS 1012
L+
Sbjct: 838 LA 839
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 82.8 bits (203), Expect = 2e-15
Identities = 125/530 (23%), Positives = 214/530 (40%), Gaps = 71/530 (13%)
Query: 281 IEEIFSTDLVPGDVMVIPLNGTIMPCDAVLI---NGTCIVNESMLTGESVPVTKTNLPNP 337
++ I + D+VPGD++ + + G +P D LI + T V++S+LTGESV VTK P
Sbjct: 137 VQRIRARDIVPGDIVEVAV-GDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195
Query: 338 SVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSIL 397
D + + + K++ LF GT + +G+ V + V TG T G++ +
Sbjct: 196 --DPRAVNQD-------KKNMLFSGTNIT-----SGKAV-GVAVATGLHTELGKIRSQMA 240
Query: 398 YPKPTDFKLYRDAYLF---LLCLVAVAGIGFIYTIINSILNEVQVGVIIIESLDIITITV 454
+P L R F L ++V + I + G + ++ I V
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300
Query: 455 -------PPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDG 507
P LPA +T + RR+ + S + G +++C DKTGTLT +
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
Query: 508 LD---LWGIQRVENARFLSPEENVC-------NEMLVKSQFVAC--MATCHSLTKIEGVL 555
+ ++ + + L E + E+ Q V C L I +
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420
Query: 556 SGDPLDLKMFEAIGWILEEATEEE-TALHNRIMPTVVRPPKQLLPESTPAGNQEMELFEL 614
+ LD + + + EATE T L ++ V Q L AG + +L
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKM--NVFDTDLQALSRVERAGACNTVIKQL 478
Query: 615 PATYEIGIVRQFPFSSALQRMSVVARVLGDRK------MDAYMKGAPEAIAGLCKPETV- 667
+ ++F + R S+ R ++KGAPE++ C V
Sbjct: 479 -------MRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVG 531
Query: 668 -------PVDFQNVLEDFTKQG-----FRVIALAHRKLESKLTWHKVQNISRDA-IENNM 714
P + +L G R +ALA R + ++ + S+ E ++
Sbjct: 532 SRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDL 591
Query: 715 DFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGM 764
F+G + M + + E A + ++A IR VM+TGD+ TAV++ R G+
Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGI 641
Score = 55.5 bits (132), Expect = 3e-07
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 11/182 (6%)
Query: 842 FQDLVPKLMLHGT----VFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGG 897
F DL P+ FAR+ P K++++E LQ+ + M GDG ND ALK+A G
Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIG 717
Query: 898 ISLSE--LEASVASPFTSKTPSISCVPNLIREGRA--ALITSFCVFKFMALYSIIQYFSV 953
I++ A A+ + + + + EGRA + + F + + + +
Sbjct: 718 IAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
Query: 954 TLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPS---GLISGALLFSV 1010
T + + L Q L+++L + + NP +++ + P S LISG L F
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837
Query: 1011 LS 1012
L+
Sbjct: 838 LA 839
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 82.8 bits (203), Expect = 2e-15
Identities = 125/530 (23%), Positives = 214/530 (40%), Gaps = 71/530 (13%)
Query: 281 IEEIFSTDLVPGDVMVIPLNGTIMPCDAVLI---NGTCIVNESMLTGESVPVTKTNLPNP 337
++ I + D+VPGD++ + + G +P D LI + T V++S+LTGESV VTK P
Sbjct: 137 VQRIRARDIVPGDIVEVAV-GDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195
Query: 338 SVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSIL 397
D + + + K++ LF GT + +G+ V + V TG T G++ +
Sbjct: 196 --DPRAVNQD-------KKNMLFSGTNIT-----SGKAV-GVAVATGLHTELGKIRSQMA 240
Query: 398 YPKPTDFKLYRDAYLF---LLCLVAVAGIGFIYTIINSILNEVQVGVIIIESLDIITITV 454
+P L R F L ++V + I + G + ++ I V
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300
Query: 455 -------PPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDG 507
P LPA +T + RR+ + S + G +++C DKTGTLT +
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
Query: 508 LD---LWGIQRVENARFLSPEENVC-------NEMLVKSQFVAC--MATCHSLTKIEGVL 555
+ ++ + + L E + E+ Q V C L I +
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420
Query: 556 SGDPLDLKMFEAIGWILEEATEEE-TALHNRIMPTVVRPPKQLLPESTPAGNQEMELFEL 614
+ LD + + + EATE T L ++ V Q L AG + +L
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKM--NVFDTDLQALSRVERAGACNTVIKQL 478
Query: 615 PATYEIGIVRQFPFSSALQRMSVVARVLGDRK------MDAYMKGAPEAIAGLCKPETV- 667
+ ++F + R S+ R ++KGAPE++ C V
Sbjct: 479 -------MRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVG 531
Query: 668 -------PVDFQNVLEDFTKQG-----FRVIALAHRKLESKLTWHKVQNISRDA-IENNM 714
P + +L G R +ALA R + ++ + S+ E ++
Sbjct: 532 SRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDL 591
Query: 715 DFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGM 764
F+G + M + + E A + ++A IR VM+TGD+ TAV++ R G+
Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGI 641
Score = 55.5 bits (132), Expect = 3e-07
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 11/182 (6%)
Query: 842 FQDLVPKLMLHGT----VFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGG 897
F DL P+ FAR+ P K++++E LQ+ + M GDG ND ALK+A G
Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIG 717
Query: 898 ISLSE--LEASVASPFTSKTPSISCVPNLIREGRA--ALITSFCVFKFMALYSIIQYFSV 953
I++ A A+ + + + + EGRA + + F + + + +
Sbjct: 718 IAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
Query: 954 TLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPS---GLISGALLFSV 1010
T + + L Q L+++L + + NP +++ + P S LISG L F
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837
Query: 1011 LS 1012
L+
Sbjct: 838 LA 839
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 82.8 bits (203), Expect = 2e-15
Identities = 125/530 (23%), Positives = 214/530 (40%), Gaps = 71/530 (13%)
Query: 281 IEEIFSTDLVPGDVMVIPLNGTIMPCDAVLI---NGTCIVNESMLTGESVPVTKTNLPNP 337
++ I + D+VPGD++ + + G +P D LI + T V++S+LTGESV VTK P
Sbjct: 137 VQRIRARDIVPGDIVEVAV-GDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195
Query: 338 SVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSIL 397
D + + + K++ LF GT + +G+ V + V TG T G++ +
Sbjct: 196 --DPRAVNQD-------KKNMLFSGTNIT-----SGKAV-GVAVATGLHTELGKIRSQMA 240
Query: 398 YPKPTDFKLYRDAYLF---LLCLVAVAGIGFIYTIINSILNEVQVGVIIIESLDIITITV 454
+P L R F L ++V + I + G + ++ I V
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300
Query: 455 -------PPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDG 507
P LPA +T + RR+ + S + G +++C DKTGTLT +
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
Query: 508 LD---LWGIQRVENARFLSPEENVC-------NEMLVKSQFVAC--MATCHSLTKIEGVL 555
+ ++ + + L E + E+ Q V C L I +
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420
Query: 556 SGDPLDLKMFEAIGWILEEATEEE-TALHNRIMPTVVRPPKQLLPESTPAGNQEMELFEL 614
+ LD + + + EATE T L ++ V Q L AG + +L
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKM--NVFDTDLQALSRVERAGACNTVIKQL 478
Query: 615 PATYEIGIVRQFPFSSALQRMSVVARVLGDRK------MDAYMKGAPEAIAGLCKPETV- 667
+ ++F + R S+ R ++KGAPE++ C V
Sbjct: 479 -------MRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVG 531
Query: 668 -------PVDFQNVLEDFTKQG-----FRVIALAHRKLESKLTWHKVQNISRDA-IENNM 714
P + +L G R +ALA R + ++ + S+ E ++
Sbjct: 532 SRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDL 591
Query: 715 DFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGM 764
F+G + M + + E A + ++A IR VM+TGD+ TAV++ R G+
Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGI 641
Score = 55.5 bits (132), Expect = 3e-07
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 11/182 (6%)
Query: 842 FQDLVPKLMLHGT----VFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGG 897
F DL P+ FAR+ P K++++E LQ+ + M GDG ND ALK+A G
Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIG 717
Query: 898 ISLSE--LEASVASPFTSKTPSISCVPNLIREGRA--ALITSFCVFKFMALYSIIQYFSV 953
I++ A A+ + + + + EGRA + + F + + + +
Sbjct: 718 IAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
Query: 954 TLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPS---GLISGALLFSV 1010
T + + L Q L+++L + + NP +++ + P S LISG L F
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837
Query: 1011 LS 1012
L+
Sbjct: 838 LA 839
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,857,296
Number of Sequences: 37866
Number of extensions: 1931137
Number of successful extensions: 4741
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 4416
Number of HSP's gapped (non-prelim): 210
length of query: 1226
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1112
effective length of database: 13,930,794
effective search space: 15491042928
effective search space used: 15491042928
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.