Search of human proteins with 148596936

Search of human proteins with 148596936

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148596936 hypoxia-inducible factor 1, alpha subunit
inhibitor [Homo sapiens]
         (349 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148596936 hypoxia-inducible factor 1, alpha subunit inhibitor...   735   0.0  
gi|223942018 jumonji domain containing 5 isoform 1 [Homo sapiens]      94   2e-19
gi|223942014 jumonji domain containing 5 isoform 2 [Homo sapiens]      94   2e-19
gi|21314714 Hspb associated protein 1 [Homo sapiens]                   86   5e-17
gi|89242134 hypothetical protein LOC129450 [Homo sapiens]              74   3e-13
gi|167860114 jumonji domain containing 7 [Homo sapiens]                60   3e-09
gi|239788849 jumonji domain containing 4 isoform 2 [Homo sapiens]      39   0.009
gi|239788847 jumonji domain containing 4 isoform 1 [Homo sapiens]      37   0.034
gi|125988395 jumonji domain containing 6 isoform 1 [Homo sapiens]      33   0.29 
gi|125988389 jumonji domain containing 6 isoform 2 [Homo sapiens]      33   0.29 
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       33   0.38 
gi|56090146 jumonji domain containing 8 [Homo sapiens]                 33   0.38 
gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]                        33   0.50 
gi|38455394 DNA-directed DNA polymerase epsilon 4 [Homo sapiens]       32   0.85 
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                     32   1.1  
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                     32   1.1  
gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]       31   1.4  
gi|56118234 proline rich 6 [Homo sapiens]                              30   2.5  
gi|106879206 chromosome 14 open reading frame 169 [Homo sapiens]       30   2.5  
gi|23346418 MYC induced nuclear antigen isoform b [Homo sapiens]       29   5.5  
gi|110227621 MYC induced nuclear antigen isoform a [Homo sapiens]      29   5.5  
gi|110227619 MYC induced nuclear antigen isoform a [Homo sapiens]      29   5.5  
gi|38569460 SNF1-like kinase 2 [Homo sapiens]                          28   9.4  
gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]                28   9.4  

>gi|148596936 hypoxia-inducible factor 1, alpha subunit inhibitor
           [Homo sapiens]
          Length = 349

 Score =  735 bits (1897), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 1   MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE 60
           MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE
Sbjct: 1   MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE 60

Query: 61  PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR 120
           PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR
Sbjct: 61  PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR 120

Query: 121 EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG 180
           EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG
Sbjct: 121 EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG 180

Query: 181 QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS 240
           QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS
Sbjct: 181 QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS 240

Query: 241 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA 300
           QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA
Sbjct: 241 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA 300

Query: 301 PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN 349
           PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
Sbjct: 301 PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN 349


>gi|223942018 jumonji domain containing 5 isoform 1 [Homo sapiens]
          Length = 454

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 72/261 (27%), Positives = 120/261 (45%), Gaps = 30/261 (11%)

Query: 40  RPIPRLSQSDPR--AEELIENEEPVVLTDTNLVYPAL-KWDLEYLQENIGNGDFSVYSAS 96
           + +PRL +   +   E+ +    PV+L      +P + KW LEY+QE  G     V   S
Sbjct: 220 KTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGS 279

Query: 97  THKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGR 156
                Y DE+                M  +EF+ K   I     +     Q  L D +  
Sbjct: 280 R----YTDEEWSQTL-----------MTVNEFISKY--IVNEPRDVGYLAQHQLFDQIP- 321

Query: 157 KIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRC 216
           ++  D    ++  +   + +    ++T N    G +G ++P H D QQNF  Q+ G K  
Sbjct: 322 ELKQDISIPDYCSLGDGEEE----EITINAWF-GPQGTISPLHQDPQQNFLVQVMGRKYI 376

Query: 217 ILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMY 276
            L+ P +   LYP+  H      SQVD +NPD E+FP F        ++ PG++L+IP+ 
Sbjct: 377 RLYSPQESGALYPHDTHL-LHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVK 435

Query: 277 WWHHIESLLNGGITITVNFWY 297
           +WH++ +L    ++ +V+FW+
Sbjct: 436 YWHYVRAL---DLSFSVSFWW 453


>gi|223942014 jumonji domain containing 5 isoform 2 [Homo sapiens]
          Length = 416

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 72/261 (27%), Positives = 120/261 (45%), Gaps = 30/261 (11%)

Query: 40  RPIPRLSQSDPR--AEELIENEEPVVLTDTNLVYPAL-KWDLEYLQENIGNGDFSVYSAS 96
           + +PRL +   +   E+ +    PV+L      +P + KW LEY+QE  G     V   S
Sbjct: 182 KTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGS 241

Query: 97  THKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGR 156
                Y DE+                M  +EF+ K   I     +     Q  L D +  
Sbjct: 242 R----YTDEEWSQTL-----------MTVNEFISKY--IVNEPRDVGYLAQHQLFDQIP- 283

Query: 157 KIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRC 216
           ++  D    ++  +   + +    ++T N    G +G ++P H D QQNF  Q+ G K  
Sbjct: 284 ELKQDISIPDYCSLGDGEEE----EITINAWF-GPQGTISPLHQDPQQNFLVQVMGRKYI 338

Query: 217 ILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMY 276
            L+ P +   LYP+  H      SQVD +NPD E+FP F        ++ PG++L+IP+ 
Sbjct: 339 RLYSPQESGALYPHDTHL-LHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVK 397

Query: 277 WWHHIESLLNGGITITVNFWY 297
           +WH++ +L    ++ +V+FW+
Sbjct: 398 YWHYVRAL---DLSFSVSFWW 415


>gi|21314714 Hspb associated protein 1 [Homo sapiens]
          Length = 488

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 78/302 (25%), Positives = 124/302 (41%), Gaps = 35/302 (11%)

Query: 51  RAEELIEN-EEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMA 109
           +A+E+I + ++P +  +    +PA  W+ +YL + +                    K M+
Sbjct: 32  KAKEIIMSLQQPAIFCNMVFDWPARHWNAKYLSQVLHGKQIRFRMGM---------KSMS 82

Query: 110 NFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMD-------- 161
               F+   N  E    EF+    D     G  R Y           K  +         
Sbjct: 83  TVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDHSKFWAYADYKYFVSLFEDKTDL 142

Query: 162 FLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQ-NFFAQIKGYKRCILFP 220
           F    W+      G+ G      + L IG  G  TP H D    N   Q++G KR  LFP
Sbjct: 143 FQDVKWSDFGFP-GRNG----QESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFP 197

Query: 221 PDQFECLYPYPV-HHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWH 279
           P+    LYP  + +      S+++  NPD +RFP F+    +   + PG VL++P +WWH
Sbjct: 198 PEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHAVTLSPGQVLFVPRHWWH 257

Query: 280 HIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPL 339
           ++ES+    +T+++N W +       +E    A  + AI R +   L  A  NPQ     
Sbjct: 258 YVESI--DPVTVSINSWIE-------LEEDHLARVEEAITRMLVCALKTA-ENPQNTRAW 307

Query: 340 LN 341
           LN
Sbjct: 308 LN 309


>gi|89242134 hypothetical protein LOC129450 [Homo sapiens]
          Length = 315

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 68/276 (24%), Positives = 117/276 (42%), Gaps = 41/276 (14%)

Query: 41  PIPRLS--QSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTH 98
           P+PRL     +   + L    +P+VL   +L     KW ++YL +  G  +  ++ A+  
Sbjct: 7   PVPRLEGVSREQFMQHLYPQRKPLVLEGIDLGPCTSKWTVDYLSQVGGKKEVKIHVAAVA 66

Query: 99  KFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQR----GGEERLYLQQTLNDTV 154
           +  +  +       NF  R+    + F + V++  + + +      +E+ YL+    D  
Sbjct: 67  QMDFISK-------NFVYRT----LPFDQLVQRAAEEKHKEFFVSEDEKYYLRSLGEDP- 114

Query: 155 GRKIVMDFL--------GFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNF 206
            RK V D             +    K++      Q  S++  I   G     HYD   N 
Sbjct: 115 -RKDVADIRKQFPLLKGDIKFPEFFKEE------QFFSSVFRISSPGLQLWTHYDVMDNL 167

Query: 207 FAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVG 266
             Q+ G KR +LF P   + LY         +   ++ DNPD  ++P F     YE  + 
Sbjct: 168 LIQVTGKKRVVLFSPRDAQYLYLKGT-----KSEVLNIDNPDLAKYPLFSKARRYECSLE 222

Query: 267 PGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPT 302
            GDVL+IP  W+H++ S   G   + VN ++K  P+
Sbjct: 223 AGDVLFIPALWFHNVISEEFG---VGVNIFWKHLPS 255


>gi|167860114 jumonji domain containing 7 [Homo sapiens]
          Length = 316

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 65/274 (23%), Positives = 108/274 (39%), Gaps = 48/274 (17%)

Query: 61  PVVLTDTNLVYPAL-KWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSN 119
           P ++ +    +PAL KW L Y +  +G+ + SV         Y D  +   F    P   
Sbjct: 51  PCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDG---YADAVRGDRFM--MPAER 105

Query: 120 REEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGR--KIVMDFLGFNWNWINKQQGKR 177
           R  + F   ++ L+   Q  G   LY+Q+  ++      +++ D L  +  W ++  GK 
Sbjct: 106 RLPLSF--VLDVLEGRAQHPGV--LYVQKQCSNLPSELPQLLPD-LESHVPWASEALGKM 160

Query: 178 GWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCD 237
                 +    +G    VT  H D  +N +  + G K  +  PP     + PY ++ P  
Sbjct: 161 P----DAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFI-PYELYTPAT 215

Query: 238 RQSQ--------------------VDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYW 277
            Q                      +D   PD  R+P++         V  G++LY+P  W
Sbjct: 216 YQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLYLPALW 275

Query: 278 WHHIESLLNGGITITVNFWYKGAPTPKRIEYPLK 311
           +HH++        I VNFWY        +EY LK
Sbjct: 276 FHHVQQSQG---CIAVNFWYD-------MEYDLK 299


>gi|239788849 jumonji domain containing 4 isoform 2 [Homo sapiens]
          Length = 447

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 44/166 (26%), Positives = 74/166 (44%), Gaps = 19/166 (11%)

Query: 165 FNWNWINKQQGKRGWGQLTSN---LLLIGMEGNVTPAHYDEQQNFFAQIK--GYKRCILF 219
           F+ +W+N+      W  L  +    +  G  G+ +P H D  ++F   +   G K+ +LF
Sbjct: 203 FSSDWLNEF-----WDALDVDDYRFVYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLF 257

Query: 220 PPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWH 279
           PP Q E L     + P D  S    D   + R  N       E     G+++++P  W H
Sbjct: 258 PPGQEEALRDRHGNLPYDVTSPALCDTHLHPR--NQLAGPPLEITQEAGEMVFVPSGWHH 315

Query: 280 HIESLLNGGITITVNF-WYKG---APTPKRIEYPLKAHQKVAIMRN 321
            + +L +   TI++N  W  G   A   + ++  L A Q+  IMR+
Sbjct: 316 QVHNLDD---TISINHNWVNGFNLANMWRFLQQELCAVQEEVIMRS 358


>gi|239788847 jumonji domain containing 4 isoform 1 [Homo sapiens]
          Length = 463

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 16/141 (11%)

Query: 165 FNWNWINKQQGKRGWGQLTSN---LLLIGMEGNVTPAHYDEQQNFFAQIK--GYKRCILF 219
           F+ +W+N+      W  L  +    +  G  G+ +P H D  ++F   +   G K+ +LF
Sbjct: 203 FSSDWLNEF-----WDALDVDDYRFVYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLF 257

Query: 220 PPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWH 279
           PP Q E L     + P D  S    D   + R  N       E     G+++++P  W H
Sbjct: 258 PPGQEEALRDRHGNLPYDVTSPALCDTHLHPR--NQLAGPPLEITQEAGEMVFVPSGWHH 315

Query: 280 HIESLLNGGITITVNF-WYKG 299
            + +L +   TI++N  W  G
Sbjct: 316 QVHNLDD---TISINHNWVNG 333


>gi|125988395 jumonji domain containing 6 isoform 1 [Homo sapiens]
          Length = 414

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 25/133 (18%)

Query: 208 AQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQ-VDFDNPDYERF------PNFQNVVG 260
           A ++G+KR  LFP      L         ++Q + + + N  Y R       P F+ +  
Sbjct: 198 ALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPL-- 255

Query: 261 YETVVGPGDVLYIPMYWWHHIESLLNGGITITVNF---------WYK---GAPTPKRIEY 308
            E +  PG+ +++P  WWH + + L+  I IT NF         W+K   G P   R  Y
Sbjct: 256 -EILQKPGETVFVPGGWWHVVLN-LDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWY 313

Query: 309 PL--KAHQKVAIM 319
            +  + H ++A++
Sbjct: 314 RILKQEHPELAVL 326


>gi|125988389 jumonji domain containing 6 isoform 2 [Homo sapiens]
          Length = 403

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 25/133 (18%)

Query: 208 AQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQ-VDFDNPDYERF------PNFQNVVG 260
           A ++G+KR  LFP      L         ++Q + + + N  Y R       P F+ +  
Sbjct: 198 ALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPL-- 255

Query: 261 YETVVGPGDVLYIPMYWWHHIESLLNGGITITVNF---------WYK---GAPTPKRIEY 308
            E +  PG+ +++P  WWH + + L+  I IT NF         W+K   G P   R  Y
Sbjct: 256 -EILQKPGETVFVPGGWWHVVLN-LDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWY 313

Query: 309 PL--KAHQKVAIM 319
            +  + H ++A++
Sbjct: 314 RILKQEHPELAVL 326


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 17/136 (12%)

Query: 3   ATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIP-RLSQSDPRAEELIENEEP 61
           A A E   +  G PREEA A     DE    +     +P P R  + +P  EE  ++E+ 
Sbjct: 130 AAAVETAPAPDGGPREEAAATVRKEDEGAAEA-----KPEPGRTRRDEPEEEE--DDEDD 182

Query: 62  VVLTDTNLVYPALKWDLEYLQENIGNGDF-SVYSASTHKFLYYDEKKMANFQNFKPRSNR 120
           +    T+L    LK+D+E     +G G F +VY     +   + E      Q+ K  +  
Sbjct: 183 LKAVATSLDGRFLKFDIE-----LGRGSFKTVYKGLDTE--TWVEVAWCELQDRK-LTKL 234

Query: 121 EEMKFHEFVEKLQDIQ 136
           E  +F E  E L+ +Q
Sbjct: 235 ERQRFKEEAEMLKGLQ 250


>gi|56090146 jumonji domain containing 8 [Homo sapiens]
          Length = 285

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 11/87 (12%)

Query: 193 GNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERF 252
           G+  P H+     +   I G KR  L+PP++       P  HP   ++ + +    Y   
Sbjct: 194 GSGVPFHW-HGPGYSEVIYGRKRWFLYPPEKT------PEFHP--NKTTLAWLRDTYPAL 244

Query: 253 PNFQNVVGYETVVGPGDVLYIPMYWWH 279
           P     +  E  +  G+VLY P  WWH
Sbjct: 245 PPSARPL--ECTIRAGEVLYFPDRWWH 269


>gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
          Length = 1012

 Score = 32.7 bits (73), Expect = 0.50
 Identities = 42/182 (23%), Positives = 73/182 (40%), Gaps = 18/182 (9%)

Query: 61  PVVLTDTNLVYPAL-KWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSN 119
           P ++ +    +PAL KW L Y +  +G+ + SV         Y D  +   F    P   
Sbjct: 51  PCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDG---YADAVRGDRFM--MPAER 105

Query: 120 REEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGR--KIVMDFLGFNWNWINKQQGKR 177
           R  + F   ++ L+   Q  G   LY+Q+  ++      +++ D L  +  W ++  GK 
Sbjct: 106 RLPLSF--VLDVLEGRAQHPGV--LYVQKQCSNLPSELPQLLPD-LESHVPWASEALGKM 160

Query: 178 GWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCD 237
                 +    +G    VT  H D  +N +  + G K  +  PP       PY ++ P  
Sbjct: 161 P----DAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSD-RPFIPYELYTPAT 215

Query: 238 RQ 239
            Q
Sbjct: 216 YQ 217


>gi|38455394 DNA-directed DNA polymerase epsilon 4 [Homo sapiens]
          Length = 117

 Score = 32.0 bits (71), Expect = 0.85
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 6  AEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLT 65
          A A A+GSG PREE G  G A         S P   + RL  +  R + L++ +  V L 
Sbjct: 2  AAAAAAGSGTPREEEGPAGEAAASQPQAPTSVPGARLSRLPLA--RVKALVKADPDVTLA 59

Query: 66 DTNLVY 71
              ++
Sbjct: 60 GQEAIF 65


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 25/109 (22%), Positives = 42/109 (38%), Gaps = 4/109 (3%)

Query: 21  GALGPAWDESQLRSYSFPTRP--IPRLSQSDPRAEELIENEEPVVLTDTN--LVYPALKW 76
           GA  P+   +     SFP R   +P    S PR  + ++    ++ T+     +Y   + 
Sbjct: 72  GAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEPEQGTLYSPEQT 131

Query: 77  DLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKF 125
            L   + ++GN   S    S     Y +     N QN     NR++  F
Sbjct: 132 SLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF 180


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 25/109 (22%), Positives = 42/109 (38%), Gaps = 4/109 (3%)

Query: 21  GALGPAWDESQLRSYSFPTRP--IPRLSQSDPRAEELIENEEPVVLTDTN--LVYPALKW 76
           GA  P+   +     SFP R   +P    S PR  + ++    ++ T+     +Y   + 
Sbjct: 72  GAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEPEQGTLYSPEQT 131

Query: 77  DLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKF 125
            L   + ++GN   S    S     Y +     N QN     NR++  F
Sbjct: 132 SLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF 180


>gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]
          Length = 1606

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 18/44 (40%), Positives = 21/44 (47%)

Query: 11  SGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEE 54
           SGSGEPR EA     +W   QL   S P  P  +  +    AEE
Sbjct: 375 SGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEE 418


>gi|56118234 proline rich 6 [Homo sapiens]
          Length = 272

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 5/60 (8%)

Query: 2  AATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEP 61
          AA+AA A+A  +   R  A   G     S+ ++   P    PRL +S PRA+E    E P
Sbjct: 25 AASAAAALAPSATRTRRSASQAG-----SKSQAVEKPPSEKPRLRRSSPRAQEEGPGEPP 79


>gi|106879206 chromosome 14 open reading frame 169 [Homo sapiens]
          Length = 641

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 37/152 (24%), Positives = 57/152 (37%), Gaps = 36/152 (23%)

Query: 135 IQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGN 194
           + Q G   RL   Q  + TV            W ++   Q + G     SN+ L      
Sbjct: 289 LYQAGCSLRLLCPQAFSTTV------------WQFLAVLQEQFG-SMAGSNVYLTPPNSQ 335

Query: 195 VTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPN 254
               HYD+ + F  Q++G K   ++ P                   +V  +       PN
Sbjct: 336 GFAPHYDDIEAFVLQLEGRKLWRVYRP-------------------RVPTEELALTSSPN 376

Query: 255 F-QNVVG---YETVVGPGDVLYIPMYWWHHIE 282
           F Q+ +G    +TV+ PGD+LY P  + H  E
Sbjct: 377 FSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAE 408


>gi|23346418 MYC induced nuclear antigen isoform b [Homo sapiens]
          Length = 464

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 26/103 (25%)

Query: 188 LIGMEGNVTPA-------HYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS 240
           L+G    +TPA       HYD+ + F  Q++G K   L+ P             P  R+ 
Sbjct: 161 LVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTV-----------PLAREY 209

Query: 241 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIES 283
            V+ +    ER         +E ++ PGD+LY P    H  ++
Sbjct: 210 SVEAE----ERIGR----PVHEFMLKPGDLLYFPRGTIHQADT 244


>gi|110227621 MYC induced nuclear antigen isoform a [Homo sapiens]
          Length = 465

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 26/103 (25%)

Query: 188 LIGMEGNVTPA-------HYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS 240
           L+G    +TPA       HYD+ + F  Q++G K   L+ P             P  R+ 
Sbjct: 161 LVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTV-----------PLAREY 209

Query: 241 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIES 283
            V+ +    ER         +E ++ PGD+LY P    H  ++
Sbjct: 210 SVEAE----ERIGR----PVHEFMLKPGDLLYFPRGTIHQADT 244


>gi|110227619 MYC induced nuclear antigen isoform a [Homo sapiens]
          Length = 465

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 26/103 (25%)

Query: 188 LIGMEGNVTPA-------HYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS 240
           L+G    +TPA       HYD+ + F  Q++G K   L+ P             P  R+ 
Sbjct: 161 LVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTV-----------PLAREY 209

Query: 241 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIES 283
            V+ +    ER         +E ++ PGD+LY P    H  ++
Sbjct: 210 SVEAE----ERIGR----PVHEFMLKPGDLLYFPRGTIHQADT 244


>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
          Length = 926

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 12/29 (41%), Positives = 13/29 (44%)

Query: 228 YPYPVHHPCDRQSQVDFDNPDYERFPNFQ 256
           YP P  +P D   Q D   PD  R P  Q
Sbjct: 861 YPTPCQYPVDGAQQSDLTGPDCPRSPGLQ 889


>gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]
          Length = 665

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 17/75 (22%), Positives = 38/75 (50%), Gaps = 5/75 (6%)

Query: 82  QENIGNGDFSVYSASTHKFLYYDEKKMANFQ---NFKPRSNREEMKFHEFVEKLQDIQQR 138
           +E++G+ D   +  +++K LY   +K  N     N++     E+ +  E +EK++ +  +
Sbjct: 366 KEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKIESMVHQ 425

Query: 139 GGEERLYL--QQTLN 151
            G +      ++TLN
Sbjct: 426 NGNKHCVFREKETLN 440


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,458,900
Number of Sequences: 37866
Number of extensions: 704119
Number of successful extensions: 1673
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1649
Number of HSP's gapped (non-prelim): 29
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.