Search of human proteins with 148596928

Search of human proteins with 148596928

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148596928 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 1 [Homo sapiens]
         (1079 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148596928 solute carrier family 4, sodium bicarbonate cotrans...  2169   0.0  
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans...  2073   0.0  
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo...  2001   0.0  
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap...  1313   0.0  
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa...  1303   0.0  
gi|155722998 solute carrier family 4, sodium bicarbonate transpo...  1097   0.0  
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp...  1079   0.0  
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp...  1079   0.0  
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans...   942   0.0  
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans...   910   0.0  
gi|156071474 solute carrier family 4, anion exchanger, member 2 ...   658   0.0  
gi|157671951 solute carrier family 4, anion exchanger, member 3 ...   647   0.0  
gi|157671953 solute carrier family 4, anion exchanger, member 3 ...   647   0.0  
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H...   564   e-160
gi|14042960 solute carrier family 4 member 11 [Homo sapiens]          231   3e-60
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  36   0.17 
gi|169161027 PREDICTED: hypothetical protein [Homo sapiens]            36   0.22 
gi|113411962 PREDICTED: hypothetical protein [Homo sapiens]            36   0.22 
gi|113403778 PREDICTED: hypothetical protein [Homo sapiens]            36   0.22 
gi|154813197 talpid3 protein [Homo sapiens]                            35   0.29 
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    35   0.38 
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ...    35   0.50 
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    35   0.50 
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]                 34   0.65 
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]                 34   0.65 
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]                 34   0.65 
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       34   0.65 
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       34   0.65 
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       34   0.65 
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        34   0.65 

>gi|148596928 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 1 [Homo sapiens]
          Length = 1079

 Score = 2169 bits (5619), Expect = 0.0
 Identities = 1079/1079 (100%), Positives = 1079/1079 (100%)

Query: 1    MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKERI 60
            MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKERI
Sbjct: 1    MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKERI 60

Query: 61   SENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDG 120
            SENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDG
Sbjct: 61   SENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDG 120

Query: 121  QEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLP 180
            QEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLP
Sbjct: 121  QEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLP 180

Query: 181  QLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTN 240
            QLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTN
Sbjct: 181  QLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTN 240

Query: 241  PDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFI 300
            PDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFI
Sbjct: 241  PDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFI 300

Query: 301  AFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKA 360
            AFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKA
Sbjct: 301  AFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKA 360

Query: 361  KDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTP 420
            KDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTP
Sbjct: 361  KDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTP 420

Query: 421  HDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLAT 480
            HDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLAT
Sbjct: 421  HDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLAT 480

Query: 481  VTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLF 540
            VTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLF
Sbjct: 481  VTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLF 540

Query: 541  NFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDA 600
            NFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDA
Sbjct: 541  NFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDA 600

Query: 601  FKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYH 660
            FKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYH
Sbjct: 601  FKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYH 660

Query: 661  NTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFP 720
            NTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFP
Sbjct: 661  NTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFP 720

Query: 721  TTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWV 780
            TTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWV
Sbjct: 721  TTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWV 780

Query: 781  CLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPW 840
            CLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPW
Sbjct: 781  CLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPW 840

Query: 841  YVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFI 900
            YVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFI
Sbjct: 841  YVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFI 900

Query: 901  PMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLC 960
            PMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLC
Sbjct: 901  PMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLC 960

Query: 961  LALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKK 1020
            LALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKK
Sbjct: 961  LALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKK 1020

Query: 1021 KKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC 1079
            KKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC
Sbjct: 1021 KKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC 1079


>gi|197927160 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 3 [Homo sapiens]
          Length = 1094

 Score = 2073 bits (5372), Expect = 0.0
 Identities = 1033/1033 (100%), Positives = 1033/1033 (100%)

Query: 1    MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKERI 60
            MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKERI
Sbjct: 1    MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKERI 60

Query: 61   SENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDG 120
            SENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDG
Sbjct: 61   SENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDG 120

Query: 121  QEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLP 180
            QEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLP
Sbjct: 121  QEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLP 180

Query: 181  QLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTN 240
            QLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTN
Sbjct: 181  QLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTN 240

Query: 241  PDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFI 300
            PDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFI
Sbjct: 241  PDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFI 300

Query: 301  AFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKA 360
            AFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKA
Sbjct: 301  AFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKA 360

Query: 361  KDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTP 420
            KDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTP
Sbjct: 361  KDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTP 420

Query: 421  HDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLAT 480
            HDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLAT
Sbjct: 421  HDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLAT 480

Query: 481  VTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLF 540
            VTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLF
Sbjct: 481  VTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLF 540

Query: 541  NFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDA 600
            NFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDA
Sbjct: 541  NFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDA 600

Query: 601  FKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYH 660
            FKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYH
Sbjct: 601  FKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYH 660

Query: 661  NTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFP 720
            NTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFP
Sbjct: 661  NTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFP 720

Query: 721  TTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWV 780
            TTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWV
Sbjct: 721  TTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWV 780

Query: 781  CLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPW 840
            CLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPW
Sbjct: 781  CLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPW 840

Query: 841  YVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFI 900
            YVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFI
Sbjct: 841  YVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFI 900

Query: 901  PMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLC 960
            PMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLC
Sbjct: 901  PMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLC 960

Query: 961  LALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKK 1020
            LALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKK
Sbjct: 961  LALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKK 1020

Query: 1021 KKKKGSLDSDNDD 1033
            KKKKGSLDSDNDD
Sbjct: 1021 KKKKGSLDSDNDD 1033


>gi|4507025 solute carrier family 4, sodium bicarbonate cotransporter,
            member 4 isoform 2 [Homo sapiens]
          Length = 1035

 Score = 2001 bits (5184), Expect = 0.0
 Identities = 996/1001 (99%), Positives = 997/1001 (99%)

Query: 79   SILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV 138
            SI    +SPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV
Sbjct: 35   SIFTSAVSPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV 94

Query: 139  EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP 198
            EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP
Sbjct: 95   EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP 154

Query: 199  ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL 258
            ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL
Sbjct: 155  ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL 214

Query: 259  NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP 318
            NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP
Sbjct: 215  NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP 274

Query: 319  VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI 378
            VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI
Sbjct: 275  VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI 334

Query: 379  VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR 438
            VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR
Sbjct: 335  VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR 394

Query: 439  TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM 498
            TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM
Sbjct: 395  TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM 454

Query: 499  QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG 558
            QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG
Sbjct: 455  QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG 514

Query: 559  LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK 618
            LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK
Sbjct: 515  LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK 574

Query: 619  VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG 678
            VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG
Sbjct: 575  VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG 634

Query: 679  GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI 738
            GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI
Sbjct: 635  GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI 694

Query: 739  FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD 798
            FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD
Sbjct: 695  FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD 754

Query: 799  QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME 858
            QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME
Sbjct: 755  QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME 814

Query: 859  TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN 918
            TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN
Sbjct: 815  TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN 874

Query: 919  GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV 978
            GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV
Sbjct: 875  GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV 934

Query: 979  MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPY 1038
            MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPY
Sbjct: 935  MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPY 994

Query: 1039 SEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC 1079
            SEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC
Sbjct: 995  SEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC 1035


>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
          Length = 1121

 Score = 1313 bits (3398), Expect = 0.0
 Identities = 671/1085 (61%), Positives = 825/1085 (76%), Gaps = 70/1085 (6%)

Query: 29   IYIGVHVPKSYRRRRRHKRKTGHKEKKEK-------ERISENYSDKSDIENADESSSSIL 81
            I+IG+ VP   +R+   K   GH    +K       ++  +  +      ++ +SS  ++
Sbjct: 31   IHIGLPVPTYPQRKTDQK---GHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLI 87

Query: 82   KPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQG 141
                SPAAE+++ ILGEED++P P  LFTE+D L   DG +MEWKE+ARWIKFEEKVE+G
Sbjct: 88   SRTRSPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEG 145

Query: 142  GERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELK 201
            GERWSKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+
Sbjct: 146  GERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELR 205

Query: 202  DKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR---------- 251
            ++V+Y LLR+HRHQTKK   RSLADIGK+VS+ +R         P++ H           
Sbjct: 206  ERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSA 265

Query: 252  ------NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRL 305
                  +  S S+NDIS  P  DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL
Sbjct: 266  NYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRL 325

Query: 306  QQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHD 365
             Q+ MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R D
Sbjct: 326  IQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNRED 385

Query: 366  LIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH 425
            LIAGIDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S  E  QMNG     GG 
Sbjct: 386  LIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGA 445

Query: 426  GGGGHGDC--------------------------------EELQRTGRFCGGLIKDIKRK 453
             GGG+G                                  EEL  TGRF GGL  DIKRK
Sbjct: 446  PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRK 505

Query: 454  APFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGA 513
             P+F SDFYD  +IQ++SAILFIYL  +TNAITFGGLLGDATDN QGV+ESFLGTA++G+
Sbjct: 506  LPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGS 565

Query: 514  IFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDA 573
            +FCLF+GQPL ILSSTGP+L+FE+LLF+FSK N  DY+EFRLWIGL SA  CLILVATDA
Sbjct: 566  LFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDA 625

Query: 574  SFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPD 633
            SF+++Y TRFTEEGFS+LISFIFIYDA KKMI    YYPIN +FK  + T + C CV PD
Sbjct: 626  SFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPD 685

Query: 634  PANISISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692
              N ++ N +  LAP+     S  ++ + T  DW+ LSKKEC  YGG L+GN+C F+PD+
Sbjct: 686  TVNTTVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDL 743

Query: 693  TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPK 752
             LMSFILF GTY+ ++ LKKFK S YFPT  R L++DF+I+ SIL+FC IDA  G++TPK
Sbjct: 744  ALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPK 803

Query: 753  LIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHK 812
            L VPS  KPT P+RGWFV PFG+NPWWV  A+ +PALLVTILIFMDQQITAVIVNRKE+K
Sbjct: 804  LHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENK 863

Query: 813  LKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLG 872
            LKK AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLG
Sbjct: 864  LKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLG 923

Query: 873  VREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMP 932
            VREQRVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+QF +R KL LMP
Sbjct: 924  VREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQFWERCKLFLMP 983

Query: 933  LKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDY 992
             KHQPD  +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIFPVMIL L+ VR+ +D+
Sbjct: 984  AKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDF 1043

Query: 993  LFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPS-IKIPMDI 1051
            +FSQHDL+++D+++PEK+  KKE +KK+K+KKG+ +  +++   P     PS IKIPM+ 
Sbjct: 1044 IFSQHDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQFP----PPSVIKIPMES 1097

Query: 1052 MEQQP 1056
            ++  P
Sbjct: 1098 VQSDP 1102


>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
            sapiens]
          Length = 1137

 Score = 1303 bits (3371), Expect = 0.0
 Identities = 671/1101 (60%), Positives = 825/1101 (74%), Gaps = 86/1101 (7%)

Query: 29   IYIGVHVPKSYRRRRRHKRKTGHKEKKEK-------ERISENYSDKSDIENADESSSSIL 81
            I+IG+ VP   +R+   K   GH    +K       ++  +  +      ++ +SS  ++
Sbjct: 31   IHIGLPVPTYPQRKTDQK---GHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLI 87

Query: 82   KPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQG 141
                SPAAE+++ ILGEED++P P  LFTE+D L   DG +MEWKE+ARWIKFEEKVE+G
Sbjct: 88   SRTRSPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEG 145

Query: 142  GERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELK 201
            GERWSKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+
Sbjct: 146  GERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELR 205

Query: 202  DKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR---------- 251
            ++V+Y LLR+HRHQTKK   RSLADIGK+VS+ +R         P++ H           
Sbjct: 206  ERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSA 265

Query: 252  ------NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRL 305
                  +  S S+NDIS  P  DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL
Sbjct: 266  NYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRL 325

Query: 306  QQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHD 365
             Q+ MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R D
Sbjct: 326  IQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNRED 385

Query: 366  LIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH 425
            LIAGIDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S  E  QMNG     GG 
Sbjct: 386  LIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGA 445

Query: 426  GGGGHGDC--------------------------------EELQRTGRFCGGLIKDIKRK 453
             GGG+G                                  EEL  TGRF GGL  DIKRK
Sbjct: 446  PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRK 505

Query: 454  APFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGA 513
             P+F SDFYD  +IQ++SAILFIYL  +TNAITFGGLLGDATDN QGV+ESFLGTA++G+
Sbjct: 506  LPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGS 565

Query: 514  IFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDA 573
            +FCLF+GQPL ILSSTGP+L+FE+LLF+FSK N  DY+EFRLWIGL SA  CLILVATDA
Sbjct: 566  LFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDA 625

Query: 574  SFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPD 633
            SF+++Y TRFTEEGFS+LISFIFIYDA KKMI    YYPIN +FK  + T + C CV PD
Sbjct: 626  SFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPD 685

Query: 634  PANISISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692
              N ++ N +  LAP+     S  ++ + T  DW+ LSKKEC  YGG L+GN+C F+PD+
Sbjct: 686  TVNTTVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDL 743

Query: 693  TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPK 752
             LMSFILF GTY+ ++ LKKFK S YFPT  R L++DF+I+ SIL+FC IDA  G++TPK
Sbjct: 744  ALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPK 803

Query: 753  LIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHK 812
            L VPS  KPT P+RGWFV PFG+NPWWV  A+ +PALLVTILIFMDQQITAVIVNRKE+K
Sbjct: 804  LHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENK 863

Query: 813  LKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLG 872
            LKK AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLG
Sbjct: 864  LKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLG 923

Query: 873  VREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ----------- 921
            VREQRVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q           
Sbjct: 924  VREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQ 983

Query: 922  -----FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIF 976
                 F +R KL LMP KHQPD  +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIF
Sbjct: 984  KKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIF 1043

Query: 977  PVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDC 1036
            PVMIL L+ VR+ +D++FSQHDL+++D+++PEK+  KKE +KK+K+KKG+ +  +++   
Sbjct: 1044 PVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQF 1101

Query: 1037 PYSEKVPS-IKIPMDIMEQQP 1056
            P     PS IKIPM+ ++  P
Sbjct: 1102 P----PPSVIKIPMESVQSDP 1118


>gi|155722998 solute carrier family 4, sodium bicarbonate
            transporter-like, member 10 [Homo sapiens]
          Length = 1088

 Score = 1097 bits (2836), Expect = 0.0
 Identities = 571/1043 (54%), Positives = 733/1043 (70%), Gaps = 56/1043 (5%)

Query: 2    EDEAVLDRGA--SFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKK-EKE 58
            ++EAV+DRG   S LK   ++E++EGH T++IGVHVP   R+  R  R  GHK +K ++E
Sbjct: 19   DEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRE 78

Query: 59   RISENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPA--PPQLFTELDELL 116
            R        S +E+  ES      P     ++R++FILG EDD     P  LFTELDE+ 
Sbjct: 79   R-------DSGLEDGRES------PSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEIC 125

Query: 117  AVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREA 176
              +G++ EW+ETARW+KFEE VE GGERWSKP+VATLSLHSLFELR+C+  G+++LD  A
Sbjct: 126  WREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHA 185

Query: 177  SSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSN------LRSLADIGKT 230
            ++L ++ +M++D Q+ +G L  +++ +V   L+++H HQ +K        +RS ADIGK 
Sbjct: 186  NTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKK 245

Query: 231  VSSASRMFTNPDN-----GSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEAS 285
             S  + M  N         +PA        S  N   D  + D     FMKK+P  AEAS
Sbjct: 246  QSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDL---HFMKKIPPGAEAS 302

Query: 286  NVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIA 345
            N+LVGE++FLD   +AFVRL  AV+L  L EVP+PTRFLFILLGP GK + YHEIGR+IA
Sbjct: 303  NILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIA 362

Query: 346  TLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKN 405
            TLM+DEVFHD+AYKAKDR+DL++GIDEFLD+V VLPPGEWDP+IRIEPPK++PS +KRK 
Sbjct: 363  TLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK- 421

Query: 406  MYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDAL 465
            + +       +G+    GGH G       ELQRTGR  GGLI DIKRKAP+F SDF DA 
Sbjct: 422  IPAVPNGTAAHGEAEPHGGHSG------PELQRTGRIFGGLILDIKRKAPYFWSDFRDAF 475

Query: 466  NIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTI 525
            ++Q L++ LF+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LF GQPLTI
Sbjct: 476  SLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTI 535

Query: 526  LSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTE 585
            L STGPVLVFE++LF F K+    YL  R  IGLW+A LC+ILVATDAS LV Y TRFTE
Sbjct: 536  LGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTE 595

Query: 586  EGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP-DPANISISNDTT 644
            E F+SLI  IFIY+A +K+ +L++ YPIN +  +   T +SC CV P +P+N       T
Sbjct: 596  EAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSN------GT 649

Query: 645  LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILF 700
            L       +S++D+       W  L+  EC    G  VG  C     +VPD+   S ILF
Sbjct: 650  LKEWRESNISASDII------WENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILF 703

Query: 701  LGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFK 760
              T T S  LK+FKTS YFPT  R ++SDFA+ L+IL   +ID  +G+ +PKL VPS FK
Sbjct: 704  FSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFK 763

Query: 761  PTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYH 820
            PT  +RGWFV P G NPWW  +AA IPALL TILIFMDQQITAVI+NRKEHKLKKG GYH
Sbjct: 764  PTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYH 823

Query: 821  LDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTG 880
            LDL  VA+++ +CS+M LPW+VAATV+SI H++SLK+E+E SAPGEQPKFLG+REQRVTG
Sbjct: 824  LDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTG 883

Query: 881  TLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFI 940
             ++FIL G SVFM  ILKFIPMPVLYGVFLYMG +SL G+QF DR+KL  MP KHQPDFI
Sbjct: 884  LMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFI 943

Query: 941  YLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLS 1000
            YLRHVPLR+VHLFT +Q+ CL LLWI+K + AAI+FP+M+LALV VRK MD LF++ +LS
Sbjct: 944  YLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELS 1003

Query: 1001 FLDDVIPEKDKKKKEDEKKKKKK 1023
            +LDD++PE  KKK ED +K++++
Sbjct: 1004 WLDDLMPESKKKKLEDAEKEEEQ 1026


>gi|90403614 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform a [Homo sapiens]
          Length = 1093

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 559/1038 (53%), Positives = 730/1038 (70%), Gaps = 45/1038 (4%)

Query: 2    EDEAVLDRG--ASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKER 59
            ++EAV+D+G  ++ L    ++EE+EGH T+Y+GV +P   R+  RH R  G K ++    
Sbjct: 19   DEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRGRG 77

Query: 60   ISENYSDKSDIENADESSSSILKPLISPAAERIRFILG-EEDDSPAPPQLFTELDELLAV 118
               +  ++     A ++ S           +R++FILG EED+   P +LFTELDE+   
Sbjct: 78   KGASQGEEGLEALAHDTPS-----------QRVQFILGTEEDEEHVPHELFTELDEICMK 126

Query: 119  DGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASS 178
            +G++ EWKETARW+KFEE VE GGERWSKP+VATLSLHSLFELR+C+  G+++LD  A+S
Sbjct: 127  EGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANS 186

Query: 179  LPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSN------LRSLADIGKTVS 232
            + ++ ++I+D Q  +  L   ++ KV   LL+KH HQ +K        +RS A++GK  S
Sbjct: 187  IEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQS 246

Query: 233  SASRMFTNPDNGSP-AMTHRNL-TSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVG 290
                M  +    SP ++   NL   + +N      +  ++   FMKK+P  AEASNVLVG
Sbjct: 247  DPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVG 306

Query: 291  EVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSD 350
            EVD LD P +AFVRL  AV+L  LTEVP+PTRFLFILLGP GK + YHEIGR++AT+M+D
Sbjct: 307  EVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTD 366

Query: 351  EVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGG 410
            E+FHD+AYKAK+R DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK++PS +KRK      
Sbjct: 367  EIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPN 426

Query: 411  ENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQAL 470
             NV      PH GGH G       ELQRTGR  GGL+ DIKRKAP++ SD+ DAL++Q L
Sbjct: 427  GNVCHIEQEPH-GGHSG------PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCL 479

Query: 471  SAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTG 530
            ++ LF+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LFAGQ LTIL STG
Sbjct: 480  ASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTG 539

Query: 531  PVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSS 590
            PVLVFE++LF F KD    YL  R  IGLW+AFLC++LVATDAS LV Y TRFTEE F+S
Sbjct: 540  PVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFAS 599

Query: 591  LISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYL 650
            LI  IFIY+A +K+I LA+ YPI+ + ++ + +L+ C C  P+  N     + TL     
Sbjct: 600  LICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPN-----NHTLQYWKD 654

Query: 651  PTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILFLGTYTS 706
              + + +++      WA L+  EC +  G  +G+ C     + PD+   S ILF  T+  
Sbjct: 655  HNIVTAEVH------WANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFIL 708

Query: 707  SMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNR 766
            S  LK FKTS YFPT  R ++SDFA+ L+I    +ID L+GV +PKL VPS FKPT  +R
Sbjct: 709  SSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDR 768

Query: 767  GWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWV 826
            GW + P G NPWW  +AA IPALL TILIFMDQQITAVI+NRKEHKLKKG GYHLDL  V
Sbjct: 769  GWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMV 828

Query: 827  AILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFIL 886
            AI++ +CS+M LPW+VAATV+SI H++SLK+E+E SAPGEQPKFLG+REQRVTG ++F+L
Sbjct: 829  AIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVL 888

Query: 887  TGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVP 946
             G SVFM  ILKFIPMPVLYGVFLYMGV+SL G+QF DRLKL  MP KHQPDFIYLRHVP
Sbjct: 889  MGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVP 948

Query: 947  LRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVI 1006
            LR+VHLFT +Q+ CL LLW++K++ AAI+FP+M+LALV VRK MD  FS+ +LS+LDD++
Sbjct: 949  LRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLM 1008

Query: 1007 PEKDKKKKEDEKKKKKKK 1024
            PE  KKK +D KKK K++
Sbjct: 1009 PESKKKKLDDAKKKAKEE 1026


>gi|90568034 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform b [Homo sapiens]
          Length = 1044

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 559/1038 (53%), Positives = 730/1038 (70%), Gaps = 45/1038 (4%)

Query: 2    EDEAVLDRG--ASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKER 59
            ++EAV+D+G  ++ L    ++EE+EGH T+Y+GV +P   R+  RH R  G K ++    
Sbjct: 19   DEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRGRG 77

Query: 60   ISENYSDKSDIENADESSSSILKPLISPAAERIRFILG-EEDDSPAPPQLFTELDELLAV 118
               +  ++     A ++ S           +R++FILG EED+   P +LFTELDE+   
Sbjct: 78   KGASQGEEGLEALAHDTPS-----------QRVQFILGTEEDEEHVPHELFTELDEICMK 126

Query: 119  DGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASS 178
            +G++ EWKETARW+KFEE VE GGERWSKP+VATLSLHSLFELR+C+  G+++LD  A+S
Sbjct: 127  EGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANS 186

Query: 179  LPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSN------LRSLADIGKTVS 232
            + ++ ++I+D Q  +  L   ++ KV   LL+KH HQ +K        +RS A++GK  S
Sbjct: 187  IEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQS 246

Query: 233  SASRMFTNPDNGSP-AMTHRNL-TSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVG 290
                M  +    SP ++   NL   + +N      +  ++   FMKK+P  AEASNVLVG
Sbjct: 247  DPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVG 306

Query: 291  EVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSD 350
            EVD LD P +AFVRL  AV+L  LTEVP+PTRFLFILLGP GK + YHEIGR++AT+M+D
Sbjct: 307  EVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTD 366

Query: 351  EVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGG 410
            E+FHD+AYKAK+R DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK++PS +KRK      
Sbjct: 367  EIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPN 426

Query: 411  ENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQAL 470
             NV      PH GGH G       ELQRTGR  GGL+ DIKRKAP++ SD+ DAL++Q L
Sbjct: 427  GNVCHIEQEPH-GGHSG------PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCL 479

Query: 471  SAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTG 530
            ++ LF+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LFAGQ LTIL STG
Sbjct: 480  ASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTG 539

Query: 531  PVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSS 590
            PVLVFE++LF F KD    YL  R  IGLW+AFLC++LVATDAS LV Y TRFTEE F+S
Sbjct: 540  PVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFAS 599

Query: 591  LISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYL 650
            LI  IFIY+A +K+I LA+ YPI+ + ++ + +L+ C C  P+  N     + TL     
Sbjct: 600  LICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPN-----NHTLQYWKD 654

Query: 651  PTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILFLGTYTS 706
              + + +++      WA L+  EC +  G  +G+ C     + PD+   S ILF  T+  
Sbjct: 655  HNIVTAEVH------WANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFIL 708

Query: 707  SMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNR 766
            S  LK FKTS YFPT  R ++SDFA+ L+I    +ID L+GV +PKL VPS FKPT  +R
Sbjct: 709  SSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDR 768

Query: 767  GWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWV 826
            GW + P G NPWW  +AA IPALL TILIFMDQQITAVI+NRKEHKLKKG GYHLDL  V
Sbjct: 769  GWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMV 828

Query: 827  AILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFIL 886
            AI++ +CS+M LPW+VAATV+SI H++SLK+E+E SAPGEQPKFLG+REQRVTG ++F+L
Sbjct: 829  AIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVL 888

Query: 887  TGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVP 946
             G SVFM  ILKFIPMPVLYGVFLYMGV+SL G+QF DRLKL  MP KHQPDFIYLRHVP
Sbjct: 889  MGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVP 948

Query: 947  LRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVI 1006
            LR+VHLFT +Q+ CL LLW++K++ AAI+FP+M+LALV VRK MD  FS+ +LS+LDD++
Sbjct: 949  LRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLM 1008

Query: 1007 PEKDKKKKEDEKKKKKKK 1024
            PE  KKK +D KKK K++
Sbjct: 1009 PESKKKKLDDAKKKAKEE 1026


>gi|151101449 solute carrier family 4, sodium bicarbonate
            cotransporter, member 9 [Homo sapiens]
          Length = 959

 Score =  942 bits (2436), Expect = 0.0
 Identities = 504/953 (52%), Positives = 656/953 (68%), Gaps = 49/953 (5%)

Query: 103  PAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELR 162
            P  P LF +L+ELL    Q +EW+ET RW+ FEEK+E    RWS PHV TL+L SL +LR
Sbjct: 51   PKDPLLFIQLNELLGWP-QALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLR 109

Query: 163  TCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLR 222
            + + +G ++LD  A SL +LVE +   ++E+  L PEL+ ++   LL++ +H  + +   
Sbjct: 110  SLLAEGLVLLDCPAQSLLELVEQVT--RVES--LSPELRGQLQALLLQRPQHYNQTTG-- 163

Query: 223  SLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDA 282
                            T P  GS   TH    S    D  + P ++Q +N   +KLP  A
Sbjct: 164  ----------------TRPCWGS---THPRKAS----DNEEAPLREQCQNPLRQKLPPGA 200

Query: 283  EASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGR 342
            EA  VL GE+ FL  P  AFVRL+  V+LG+LTEV +P+RF  +LLGP    K YHE+GR
Sbjct: 201  EAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGR 260

Query: 343  AIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDK 402
            A A L+SD  F     +A + HDL+A +D FL+EV VLPPG WDP  RI PPK LPS  K
Sbjct: 261  AAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHK 320

Query: 403  RKNMYSGGENVQMNGD-----TPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFF 457
            R       +  ++ G      T  +  H  G H    ELQRTGR  GGLI+D++RK P++
Sbjct: 321  RLP----SQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWY 376

Query: 458  ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 517
             SDF DAL++Q  SA+L+IYLATVTNAITFGGLLGDATD  QGVLESFLGTAV+GA FCL
Sbjct: 377  PSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCL 436

Query: 518  FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 577
             AGQPLTILSSTGPVLVFERLLF+FS+D + DYL FRLW+G+W A  CL+LVAT+AS LV
Sbjct: 437  MAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLV 496

Query: 578  QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 637
            +YFTRFTEEGF +LIS IFIYDA  KM+ L   YPI    K G ++ + C C  P P   
Sbjct: 497  RYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPG-SSAYGCLCQYPGPGG- 551

Query: 638  SISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSF 697
            + S      P+    + S D+      + + L   EC++ GG+  G  C+ VPDI   S 
Sbjct: 552  NESQWIRTRPKDRDDIVSMDL---GLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSL 608

Query: 698  ILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPS 757
            +LFL ++  +MALK  KTS +FP+  RK +SDF+ +L+IL+ C +DA +G+ TPKL+VP 
Sbjct: 609  LLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPR 668

Query: 758  EFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGA 817
            EFKPT P RGW V PFG NPWW  +AAA+PALL++ILIFMDQQITAVI+NR E++L+KGA
Sbjct: 669  EFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGA 728

Query: 818  GYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQR 877
            G+HLDLF VA+LM++ S + LPWYV+ATVIS+AH+DSL+ E+   APGE+P FLG+REQR
Sbjct: 729  GFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQR 788

Query: 878  VTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQP 937
            +TG +VFILTG S+F+AP+LKFIPMPVLYG+FLYMGVA+L+ +QF +R+KLLLMP KHQP
Sbjct: 789  LTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQP 848

Query: 938  DFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQH 997
            D + LRHVPL RVHLFT +Q+ CL LLWI+KST AAIIFP+M+L LV VRK ++ +FS  
Sbjct: 849  DLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQ 908

Query: 998  DLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMD 1050
            +L +LD+++PE++  +   EK  + +     SD++DS+  Y  K P I I ++
Sbjct: 909  ELLWLDELMPEEE--RSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN 959


>gi|134288865 solute carrier family 4, sodium bicarbonate
            cotransporter, member 7 [Homo sapiens]
          Length = 1214

 Score =  910 bits (2353), Expect = 0.0
 Identities = 466/829 (56%), Positives = 592/829 (71%), Gaps = 35/829 (4%)

Query: 245  SPAMTHRNLTSSSLNDISDKPEKDQLKNK----------FMKKLPRDAEASNVLVGEVDF 294
            SP     NL +S   +I         +N           FM+K+P  AEASNVLVGEVDF
Sbjct: 379  SPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDF 438

Query: 295  LDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFH 354
            L+ P IAFVRL  AV+L  LTEVPVPTRFLF+LLGP GKA  YHEIGR+IATLM+DE+FH
Sbjct: 439  LERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFH 498

Query: 355  DIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQ 414
            D+AYKAKDR+DL++GIDEFLD+V VLPPGEWDP+IRIEPPKS+PS +KRK       +  
Sbjct: 499  DVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTP 558

Query: 415  MNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAIL 474
              G+TP +  H  G      ELQRTGR  GGLI DIKRKAPFF SDF DAL++Q L++IL
Sbjct: 559  TLGETPKEAAHHAG-----PELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASIL 613

Query: 475  FIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLV 534
            F+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LFAGQPLTIL STGPVLV
Sbjct: 614  FLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLV 673

Query: 535  FERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISF 594
            FE++L+ F +D    YL  R  IGLW++FLC++LVATDAS LV Y TRFTEE F++LI  
Sbjct: 674  FEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICI 733

Query: 595  IFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCV-PPDPANISISNDTTLAPEYLPTM 653
            IFIY+A +K+  L + Y  N +  +   T +SC C  PP+P+N       TLA      +
Sbjct: 734  IFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSN------ETLAQWKKDNI 787

Query: 654  SSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILFLGTYTSSMA 709
            ++    HN +  W  L+  EC K  G  +G+ C     ++PD+     ILF  T+  S  
Sbjct: 788  TA----HNIS--WRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSF 841

Query: 710  LKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWF 769
            LK+FKT  YFPT  R  ISDFA+ L+I+I   ID LVGV +PKL VP +F+PT P RGW 
Sbjct: 842  LKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWI 901

Query: 770  VPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAIL 829
            + P G+NPWW  L AAIPALL TILIFMDQQITAVI+NRKEHKLKKGAGYHLDL  V ++
Sbjct: 902  ISPLGDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVM 961

Query: 830  MVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGL 889
            + +CS+M LPW+VAATV+SI+H++SLK+E+E SAPGEQPKFLG+REQRVTG ++FIL GL
Sbjct: 962  LGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGL 1021

Query: 890  SVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRR 949
            SVFM  +LKFIPMPVLYGVFLYMGV+SL G+Q  DR+KL  MP KHQPD IYLR+VPL +
Sbjct: 1022 SVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWK 1081

Query: 950  VHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEK 1009
            VH+FT +Q+ CL LLW++K + AA++FP+M+LALV VRK MD  F++ +LS+LDD++PE 
Sbjct: 1082 VHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPES 1141

Query: 1010 DKKKKEDEKKKKKKKGS--LDSDNDDSDCPYSEKVPSIKIPMDIMEQQP 1056
             KKK++D+KKK+K++    L  D+D    P+ E    ++IP+  ++  P
Sbjct: 1142 KKKKEDDKKKKEKEEAERMLQDDDDTVHLPF-EGGSLLQIPVKALKYSP 1189



 Score =  209 bits (532), Expect = 1e-53
 Identities = 121/275 (44%), Positives = 169/275 (61%), Gaps = 23/275 (8%)

Query: 2   EDEAVLDRG--ASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKER 59
           ++EAV+D G  +S +    ++EE+E H  +YIGVHVP S   RRRH+ + GHK    + +
Sbjct: 14  DEEAVVDLGKTSSTVNTKFEKEELESHRAVYIGVHVPFSKESRRRHRHR-GHKHHHRRRK 72

Query: 60  ISENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPA--PPQLFTELDELLA 117
             E     SD E+  ES      P     ++R++FILG EDD     P  LFTE+DEL  
Sbjct: 73  DKE-----SDKEDGRES------PSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCY 121

Query: 118 VDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREAS 177
            DG+E EWKETARW+KFEE VE GG+RWSKP+VATLSLHSLFELR+C+  G++MLD  AS
Sbjct: 122 RDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRAS 181

Query: 178 SLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKK------SNLRSLADIGKTV 231
           +L ++ +M++D+ I +G L   +++ V   LL++H HQ +K        +RS ADIGK  
Sbjct: 182 TLDEIADMVLDNMIASGQLDESIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKH 241

Query: 232 SSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPE 266
           S    +  N + G  A  H   T  S +++S + E
Sbjct: 242 SDPHLLERNGE-GLSASRHSLRTGLSASNLSLRGE 275


>gi|156071474 solute carrier family 4, anion exchanger, member 2
            (erythrocyte membrane protein band 3-like 1) [Homo
            sapiens]
          Length = 1241

 Score =  658 bits (1697), Expect = 0.0
 Identities = 376/945 (39%), Positives = 552/945 (58%), Gaps = 63/945 (6%)

Query: 105  PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 164
            P ++F EL+ELL    QE +W+ETARWIKFEE VE+  ERW KPHVA+LS  SL ELR  
Sbjct: 320  PHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 379

Query: 165  MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLR-- 222
            +  G+++LD +  +LP +   +V+  + +  +K E +  V   LL KH H + + +    
Sbjct: 380  LAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFP 439

Query: 223  ---SLADIGKTVSS--ASRMFTNPDNGSPAMTHRNLTSSSLNDISDKP----------EK 267
               S   +G  +         ++P    P M     T   +    + P           K
Sbjct: 440  RNISAGSLGSLLGHHHGQGAESDPHVTEPLMGGVPETRLEVERERELPPPAPPAGITRSK 499

Query: 268  DQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFIL 327
             + + K ++K+P +AEA+ VLVG V+FL  P +AFVRL++AV L A+ EVPVP RFLF+L
Sbjct: 500  SKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLL 559

Query: 328  LGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDP 387
            LGP      YHEIGR+I+TLMSD+ FH+ AY A +R DL+  I+ FLD  +VLPP E   
Sbjct: 560  LGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQG 619

Query: 388  AIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGG-------GGHGDCEELQRTG 440
               +           +K    G       G  P               G  + + L+RTG
Sbjct: 620  EELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTG 679

Query: 441  RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500
            R  GGLI+D++R+ P + SDF DAL+ Q L+A++FIY A ++ AITFGGLLG+ T ++ G
Sbjct: 680  RPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIG 739

Query: 501  VLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLW 560
            V E  + TA+ G +FCL   QPL ++  +GP+LVFE   F+F   N+ +YL  R+WIG W
Sbjct: 740  VSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFW 799

Query: 561  SAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVG 620
              FL L++VA + SFLV++ +RFT+E F+ LIS IFIY+ F K++K+   +P++      
Sbjct: 800  LVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHG----- 854

Query: 621  YNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGN 680
                    C   + + +    + T A    PT+   +         +   +    K  G 
Sbjct: 855  --------CSASNSSEVDGGENMTWAGAR-PTLGPGNR--------SLAGQSGQGKPRGQ 897

Query: 681  LVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFC 740
                     P+  L+S +L  GT+  +  L+KFK S +FP   R++I DF + ++ILI  
Sbjct: 898  ---------PNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMV 948

Query: 741  VID-ALVGVDTPKLIVPSEFKPTSPN-RGWFVPPFGEN---PWWVCLAAAIPALLVTILI 795
            ++D ++    T KL VPS F  T+P  RGW + P GE    P W+ +A+ +PA+LV ILI
Sbjct: 949  LVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILI 1008

Query: 796  FMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSL 855
            FM+ QIT +I+++KE  L+KG+G+HLDL  +  +  IC+L  LPW  AATV S+ H ++L
Sbjct: 1009 FMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANAL 1068

Query: 856  KMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVA 915
             + ++  APG++PK   V+EQRVTG LV +L GLS+ +  +L+ IP+ VL+G+FLYMGV 
Sbjct: 1069 TVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVT 1128

Query: 916  SLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAII 975
            SLNG+QF +RL LLLMP KH PD  Y++ V   R+HLFT LQ+LCLALLW + ST A++ 
Sbjct: 1129 SLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLA 1188

Query: 976  FPVMILALVAVRK-GMDYLFSQHDLSFLD--DVIPEKDKKKKEDE 1017
            FP +++  V +R   +  +F+  ++  LD  +  P  D+++  DE
Sbjct: 1189 FPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDE 1233


>gi|157671951 solute carrier family 4, anion exchanger, member 3
            isoform 1 [Homo sapiens]
          Length = 1232

 Score =  647 bits (1669), Expect = 0.0
 Identities = 385/953 (40%), Positives = 547/953 (57%), Gaps = 87/953 (9%)

Query: 105  PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 164
            P ++F EL+EL+    QE  W+ETARWIKFEE VE+  ERW KPHVA+LS  SL ELR  
Sbjct: 318  PHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 377

Query: 165  MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSL 224
            +  G+ +LD E ++LP +  ++V+  I +  ++PE +  V  TLL KH H     +    
Sbjct: 378  IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKD-SGF 436

Query: 225  ADIGKTVSSASRMFTN--------PDNGSPAMTHRNLTSSSL----NDISDKP------E 266
                 + SS + +  N        PD   P M       + L     D  +KP      +
Sbjct: 437  FPRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGD 496

Query: 267  KDQLKN-KFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLF 325
              + K+ K ++K+P DAEA+ VLVG V FL+ P  AFVRL +AV+L ++ EVPVP RFLF
Sbjct: 497  GHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLF 556

Query: 326  ILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEW 385
            ++LGP   +  YHE+GR+IATLMSD++FH+ AY+A DR DL++ I EFLD  IV+PP E 
Sbjct: 557  VMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEV 616

Query: 386  DPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHG----------GGGHGDCEE 435
            +    +    +      RK      E  Q   +    GG+           GG     E+
Sbjct: 617  EGRDLLRSVAAFQRELLRKRR----EREQTKVEMTTRGGYTAPGKELSLELGGSEATPED 672

Query: 436  --LQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGD 493
              L RTG   GGL++D++R+ P + SD  DAL+ Q ++A+LFIY A ++ AITFGGLLG+
Sbjct: 673  DPLLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGE 732

Query: 494  ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 553
             T+ + GV E  + TAV G +F L   QPL ++  +GP+LVFE   F F +  + +YL  
Sbjct: 733  KTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTG 792

Query: 554  RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 613
            R+W+GLW     L LVA + SFLV+Y + FT+E F+ LIS IFIY+ F K+ K+   +P+
Sbjct: 793  RVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL 852

Query: 614  NSNFKVGYNTLFSCTCVPPDPANISISNDTTLAP--EYLPTMSSTDMYHNTTFDWAFLSK 671
               +             PP+ A +  S D  L P    LP         N          
Sbjct: 853  LPFY-------------PPEGA-LEGSLDAGLEPNGSALPPTEGPPSPRNQ--------- 889

Query: 672  KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 731
                              P+  L+S IL LGT+  +  L+KF+ S +    AR++I DF 
Sbjct: 890  ------------------PNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFG 931

Query: 732  IILSILIFCVID-ALVGVDTPKLIVPSEFKPTSPN-RGWFVPPFGEN---PWWVCLAAAI 786
            I +SIL+  ++D ++    T KL VP+    TSP+ R WF+PP G     P W+ +AAA+
Sbjct: 932  IPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAV 991

Query: 787  PALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATV 846
            PALLV ILIFM+ QITA+IV++K  +L KG+G+HLDL  +  L  +C L  LPW  AATV
Sbjct: 992  PALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATV 1051

Query: 847  ISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLY 906
             S+ H+++L +     APG++P+   VREQRVTG L+  L GLS+ M  +L+ IP+ VL+
Sbjct: 1052 RSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLF 1111

Query: 907  GVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWI 966
            G+FLYMGV SL+G+Q   RL L+LMP KH P+  Y+  V   R+HLFT +Q+ C+ALLW+
Sbjct: 1112 GIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWV 1171

Query: 967  LKSTVAAIIFPVMILALVAVRKG-MDYLFSQHDLSFLD--DVIPEKDKKKKED 1016
            +KST A++ FP ++L  V +R   +  LF   +L  LD  D  P  D+  +++
Sbjct: 1172 VKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQDE 1224


>gi|157671953 solute carrier family 4, anion exchanger, member 3
            isoform 2 [Homo sapiens]
          Length = 1259

 Score =  647 bits (1669), Expect = 0.0
 Identities = 385/953 (40%), Positives = 547/953 (57%), Gaps = 87/953 (9%)

Query: 105  PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 164
            P ++F EL+EL+    QE  W+ETARWIKFEE VE+  ERW KPHVA+LS  SL ELR  
Sbjct: 345  PHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 404

Query: 165  MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSL 224
            +  G+ +LD E ++LP +  ++V+  I +  ++PE +  V  TLL KH H     +    
Sbjct: 405  IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKD-SGF 463

Query: 225  ADIGKTVSSASRMFTN--------PDNGSPAMTHRNLTSSSL----NDISDKP------E 266
                 + SS + +  N        PD   P M       + L     D  +KP      +
Sbjct: 464  FPRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGD 523

Query: 267  KDQLKN-KFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLF 325
              + K+ K ++K+P DAEA+ VLVG V FL+ P  AFVRL +AV+L ++ EVPVP RFLF
Sbjct: 524  GHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLF 583

Query: 326  ILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEW 385
            ++LGP   +  YHE+GR+IATLMSD++FH+ AY+A DR DL++ I EFLD  IV+PP E 
Sbjct: 584  VMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEV 643

Query: 386  DPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHG----------GGGHGDCEE 435
            +    +    +      RK      E  Q   +    GG+           GG     E+
Sbjct: 644  EGRDLLRSVAAFQRELLRKRR----EREQTKVEMTTRGGYTAPGKELSLELGGSEATPED 699

Query: 436  --LQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGD 493
              L RTG   GGL++D++R+ P + SD  DAL+ Q ++A+LFIY A ++ AITFGGLLG+
Sbjct: 700  DPLLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGE 759

Query: 494  ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 553
             T+ + GV E  + TAV G +F L   QPL ++  +GP+LVFE   F F +  + +YL  
Sbjct: 760  KTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTG 819

Query: 554  RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 613
            R+W+GLW     L LVA + SFLV+Y + FT+E F+ LIS IFIY+ F K+ K+   +P+
Sbjct: 820  RVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL 879

Query: 614  NSNFKVGYNTLFSCTCVPPDPANISISNDTTLAP--EYLPTMSSTDMYHNTTFDWAFLSK 671
               +             PP+ A +  S D  L P    LP         N          
Sbjct: 880  LPFY-------------PPEGA-LEGSLDAGLEPNGSALPPTEGPPSPRNQ--------- 916

Query: 672  KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 731
                              P+  L+S IL LGT+  +  L+KF+ S +    AR++I DF 
Sbjct: 917  ------------------PNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFG 958

Query: 732  IILSILIFCVID-ALVGVDTPKLIVPSEFKPTSPN-RGWFVPPFGEN---PWWVCLAAAI 786
            I +SIL+  ++D ++    T KL VP+    TSP+ R WF+PP G     P W+ +AAA+
Sbjct: 959  IPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAV 1018

Query: 787  PALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATV 846
            PALLV ILIFM+ QITA+IV++K  +L KG+G+HLDL  +  L  +C L  LPW  AATV
Sbjct: 1019 PALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATV 1078

Query: 847  ISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLY 906
             S+ H+++L +     APG++P+   VREQRVTG L+  L GLS+ M  +L+ IP+ VL+
Sbjct: 1079 RSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLF 1138

Query: 907  GVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWI 966
            G+FLYMGV SL+G+Q   RL L+LMP KH P+  Y+  V   R+HLFT +Q+ C+ALLW+
Sbjct: 1139 GIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWV 1198

Query: 967  LKSTVAAIIFPVMILALVAVRKG-MDYLFSQHDLSFLD--DVIPEKDKKKKED 1016
            +KST A++ FP ++L  V +R   +  LF   +L  LD  D  P  D+  +++
Sbjct: 1199 VKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQDE 1251


>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
            sapiens]
          Length = 911

 Score =  564 bits (1453), Expect = e-160
 Identities = 341/933 (36%), Positives = 517/933 (55%), Gaps = 99/933 (10%)

Query: 103  PAPPQLFTELDELLAVD-GQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFEL 161
            P   +++ EL EL+  +  QE+ W E ARW++ EE + + G  W +PH++ L+  SL EL
Sbjct: 52   PGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLEL 110

Query: 162  RTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNL 221
            R    KG+++LD + +SL  +   ++D  I    ++P+ ++++   LL KH H      L
Sbjct: 111  RRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHA---GEL 167

Query: 222  RSLADIGKTVSSASRMFTNPDNGSPAMT-HRNLTSSSLNDISDKPEKDQLKNKFMKKLPR 280
             +L  +   V + S      D   P +  H +L +    +  D   +    +  ++K+P 
Sbjct: 168  EALGGVKPAVLTRSG-----DPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPP 222

Query: 281  DAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEI 340
            D+EA+ VLVG  DFL+ P + FVRLQ+A  L A+ E+PVP RFLF+LLGP+     Y ++
Sbjct: 223  DSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQL 281

Query: 341  GRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPA--------IRIE 392
            GRA ATLMS+ VF   AY A+ R +L+  ++ FLD  +VLPP +            ++ E
Sbjct: 282  GRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRE 341

Query: 393  PPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKR 452
              +    S   K   S  + + +NG             G  + LQ+TG+  GGL++DI+R
Sbjct: 342  LLRRRYQSSPAKPDSSFYKGLDLNG-------------GPDDPLQQTGQLFGGLVRDIRR 388

Query: 453  KAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSG 512
            + P++ SD  DA + Q L+A++FIY A ++ AITFGGLLG+ T N  GV E  + TAV G
Sbjct: 389  RYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQG 448

Query: 513  AIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATD 572
             +F L   QPL ++  +GP+LVFE   F+F + N  +Y+  R+WIG W   L +++VA +
Sbjct: 449  ILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFE 508

Query: 573  ASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP 632
             SFLV++ +R+T+E FS LIS IFIY+ F K+IK+   +P+   +   YN L       P
Sbjct: 509  GSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTY--NYNVLMVPKPQGP 566

Query: 633  DPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692
             P    +S         L  M+        TF +A + +K                    
Sbjct: 567  LPNTALLS---------LVLMAG-------TFFFAMMLRK-------------------- 590

Query: 693  TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALV-GVDTP 751
                                FK S YFP   R++I DF + +SILI  ++D  +    T 
Sbjct: 591  --------------------FKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQ 630

Query: 752  KLIVPSEFK-PTSPNRGWFVPPFG---ENPWWVCLAAAIPALLVTILIFMDQQITAVIVN 807
            KL VP  FK   S  RGW + P G   E P W+  A+A+PALLV ILIF++ QIT +IV+
Sbjct: 631  KLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVS 690

Query: 808  RKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQ 867
            + E K+ KG+G+HLDL  V  +  + +L  +PW  A TV S+ H ++L +  + S PG  
Sbjct: 691  KPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAA 750

Query: 868  PKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLK 927
             +   V+EQR++G LV +L GLS+ M PIL  IP+ VL+G+FLYMGV SL+G+Q  DR+ 
Sbjct: 751  AQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRIL 810

Query: 928  LLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVR 987
            LL  P K+ PD  Y++ V   R+HLFT +Q++CLA+LW++KST A++  P +++  V +R
Sbjct: 811  LLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLR 870

Query: 988  KG-MDYLFSQHDLSFL--DDVIPEKDKKKKEDE 1017
            +  +  +F   +L  L  DD     D+++  DE
Sbjct: 871  RVLLPLIFRNVELQCLDADDAKATFDEEEGRDE 903


>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
          Length = 891

 Score =  231 bits (589), Expect = 3e-60
 Identities = 184/681 (27%), Positives = 310/681 (45%), Gaps = 74/681 (10%)

Query: 322 RFLFILLGPKG--KAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 379
           RF+ ++L P      K+  E+ R  AT+ SD  F     + +   +    +      + +
Sbjct: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307

Query: 380 LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 439
           +  G   P  +     SLP+                         H       C++    
Sbjct: 308 VSHGPVAPRTKERSTVSLPA-------------------------HRHPEPPKCKDFVPF 342

Query: 440 GRFCGGLIKDIKRKAPFFASDFYDALNIQA------LSAILFIYLATVTNAITFGGLLGD 493
           G+   G+ +DI R+ P +  DF D +  +       ++  LF+Y A +   I FG L  +
Sbjct: 343 GK---GIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDE 399

Query: 494 ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 553
            TD    V ++  G ++ G ++ LF+GQPL IL +T P+ ++ +++     D + D+  F
Sbjct: 400 NTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSF 459

Query: 554 RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 613
             W GLW++F   +    + S ++  F R TEE  +  IS  F+ DA K  +K+   Y  
Sbjct: 460 YAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-Y 518

Query: 614 NSNFKVGYNTLFSCTCVPPDP--ANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSK 671
             ++   Y+T  + + V      A+++ S  T L   +L   S T++   T    A    
Sbjct: 519 YGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLA--SPTELPSATHSGQA---- 572

Query: 672 KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 731
                                 ++S ++ LGT      L +FK SPY     R+++SD A
Sbjct: 573 --------------------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCA 612

Query: 732 IILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLV 791
           + +++L F    +L+     + I  S+F+       + +             A     L+
Sbjct: 613 LPIAVLAF----SLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLL 668

Query: 792 TILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAH 851
           ++L F++Q + A +VN  E++L KG  YH DL  +AI+    SL  LPW  AA   S  H
Sbjct: 669 SMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLH 728

Query: 852 IDSLKMETETSAPGE-QPKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVF 909
           + +L +  E    G      + V+E R+T     +L GLS+ + P+ L++IP PVLYG+F
Sbjct: 729 VRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLF 788

Query: 910 LYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKS 969
           LY+ + SL+G Q + R+ LLL      P   Y+R VP R++H FT LQVL L LL     
Sbjct: 789 LYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGM 848

Query: 970 T---VAAIIFPVMILALVAVR 987
           +      +IFP++++A++ +R
Sbjct: 849 SSLPYMKMIFPLIMIAMIPIR 869


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 36.2 bits (82), Expect = 0.17
 Identities = 17/62 (27%), Positives = 37/62 (59%), Gaps = 2/62 (3%)

Query: 37  KSYRRRRRHKR--KTGHKEKKEKERISENYSDKSDIENADESSSSILKPLISPAAERIRF 94
           KS +R+++H++  +   KEKK++++  ++ S +S+ EN +    S ++P   P     RF
Sbjct: 226 KSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRF 285

Query: 95  IL 96
           ++
Sbjct: 286 LM 287



 Score = 30.8 bits (68), Expect = 7.2
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 11/79 (13%)

Query: 1008 EKDKKKKEDEKKKKKKKGSLDSDNDDSDC---PYS----EKVPSIKIPMDIMEQQPFLSD 1060
            +  +K K+++KK+KK K S  S+++  +    P S    E++P I     +M + P    
Sbjct: 236  KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSP---- 291

Query: 1061 SKPSDRERSPTFLERHTSC 1079
             K  ++ER     ER   C
Sbjct: 292  PKADEKERKNREREREREC 310


>gi|169161027 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 219

 Score = 35.8 bits (81), Expect = 0.22
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 14/87 (16%)

Query: 369 GIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH--- 425
           G DEF+ +V+V+ PGE+   +    P   P+SD   +   GG  V+  G     G     
Sbjct: 58  GDDEFIPQVLVVRPGEYQTLL----PARGPTSDPHHHPCPGGAPVRNTGSEDGSGSSSAA 113

Query: 426 ----GGGGHGDCE---ELQRTGRFCGG 445
               G GGH   +     QRTGR   G
Sbjct: 114 RKATGQGGHRLLQWVKAAQRTGRTIPG 140


>gi|113411962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 254

 Score = 35.8 bits (81), Expect = 0.22
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 14/87 (16%)

Query: 369 GIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH--- 425
           G DEF+ +V+V+ PGE+   +    P   P+SD   +   GG  V+  G     G     
Sbjct: 93  GDDEFIPQVLVVRPGEYQTLL----PARGPTSDPHHHPCPGGAPVRNTGSEDGSGSSSAA 148

Query: 426 ----GGGGHGDCE---ELQRTGRFCGG 445
               G GGH   +     QRTGR   G
Sbjct: 149 RKATGQGGHRLLQWVKAAQRTGRTIPG 175


>gi|113403778 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 219

 Score = 35.8 bits (81), Expect = 0.22
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 14/87 (16%)

Query: 369 GIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH--- 425
           G DEF+ +V+V+ PGE+   +    P   P+SD   +   GG  V+  G     G     
Sbjct: 58  GDDEFIPQVLVVRPGEYQTLL----PARGPTSDPHHHPCPGGAPVRNTGSEDGSGSSSAA 113

Query: 426 ----GGGGHGDCE---ELQRTGRFCGG 445
               G GGH   +     QRTGR   G
Sbjct: 114 RKATGQGGHRLLQWVKAAQRTGRTIPG 140


>gi|154813197 talpid3 protein [Homo sapiens]
          Length = 1472

 Score = 35.4 bits (80), Expect = 0.29
 Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 17/108 (15%)

Query: 27  HTIYIGVHVPKSYRRRRRHKRKTG------HKEKKEKERISENYSDKSDIENADESSSSI 80
           H + +   +P S R+     +K          EKK+  +++       DI++   SS+ +
Sbjct: 696 HPVTVTTSIPPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADV 755

Query: 81  LKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKET 128
           L PL SP           ++ S  P Q + +  E++ VD +E+++  T
Sbjct: 756 LSPLSSP-----------KEASLPPVQTWIKTPEIMKVDEEEVKFPGT 792


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
            sapiens]
          Length = 1954

 Score = 35.0 bits (79), Expect = 0.38
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)

Query: 1004 DVIPEKDKKKK-EDEKKKKKKKGSLDSDNDDSD 1035
            D  P K KKKK +D+K+KK K+   D D DD+D
Sbjct: 92   DYSPNKKKKKKLKDKKEKKAKRKKKDEDEDDND 124


>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
            isoform 1 [Homo sapiens]
          Length = 1112

 Score = 34.7 bits (78), Expect = 0.50
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 9/58 (15%)

Query: 1008 EKDK---KKKEDEKKKKKKKGSLDSDNDDSDCP------YSEKVPSIKIPMDIMEQQP 1056
            EKDK   K+KE EKK K++  SL +++D+   P       +E++P   +P D  ++ P
Sbjct: 647  EKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDP 704


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
            isoform 2 [Homo sapiens]
          Length = 1153

 Score = 34.7 bits (78), Expect = 0.50
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 9/58 (15%)

Query: 1008 EKDK---KKKEDEKKKKKKKGSLDSDNDDSDCP------YSEKVPSIKIPMDIMEQQP 1056
            EKDK   K+KE EKK K++  SL +++D+   P       +E++P   +P D  ++ P
Sbjct: 738  EKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDP 795


>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
          Length = 1260

 Score = 34.3 bits (77), Expect = 0.65
 Identities = 63/274 (22%), Positives = 101/274 (36%), Gaps = 35/274 (12%)

Query: 22  EVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEK-----KEKERISENYSDKSDIENADES 76
           EV    T+  G+   KS ++   H  KT  K K     K++ER    + + SD++  ++ 
Sbjct: 371 EVSKIVTVSTGIK-KKSNKKTNEHGMKTFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKI 429

Query: 77  SSSILKPLI---SPAAERIRFILGEEDDSPAPPQL--FTELDELLAVDGQEMEWKETARW 131
            +   +  +      AE   FI   E  +    QL    EL ++    G E   +E    
Sbjct: 430 ENRTERSDVLDGKRGAEDPGFIFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLC 489

Query: 132 IKFEEKVEQGGERWSKPHVATLSLHS-LFELRTCMEKGSIMLDREASSLPQLVEMIVDHQ 190
            K E+++    E        +LS  S  F   +  +KG   L    S   +  +  V H+
Sbjct: 490 NKKEKRITNEQEE-----TYSLSQSSGKFHQESKFDKGQNSLTCNKSKASR--QTFVIHK 542

Query: 191 IETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTH 250
           +E   L P  KDKVT               +    D+     +A+    +  N     TH
Sbjct: 543 LEKDNLLPNQKDKVT---------------IYENLDVTNEFHTANLSTKDNGNLCDYGTH 587

Query: 251 RNL-TSSSLNDISDKPEKDQLKNKFMKKLPRDAE 283
             L     + DI    + +   NK  KK+ R  E
Sbjct: 588 NILDLKKYVTDIQPSEQNESNINKLRKKVNRKTE 621


>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
          Length = 1265

 Score = 34.3 bits (77), Expect = 0.65
 Identities = 63/274 (22%), Positives = 101/274 (36%), Gaps = 35/274 (12%)

Query: 22  EVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEK-----KEKERISENYSDKSDIENADES 76
           EV    T+  G+   KS ++   H  KT  K K     K++ER    + + SD++  ++ 
Sbjct: 371 EVSKIVTVSTGIK-KKSNKKTNEHGMKTFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKI 429

Query: 77  SSSILKPLI---SPAAERIRFILGEEDDSPAPPQL--FTELDELLAVDGQEMEWKETARW 131
            +   +  +      AE   FI   E  +    QL    EL ++    G E   +E    
Sbjct: 430 ENRTERSDVLDGKRGAEDPGFIFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLC 489

Query: 132 IKFEEKVEQGGERWSKPHVATLSLHS-LFELRTCMEKGSIMLDREASSLPQLVEMIVDHQ 190
            K E+++    E        +LS  S  F   +  +KG   L    S   +  +  V H+
Sbjct: 490 NKKEKRITNEQEE-----TYSLSQSSGKFHQESKFDKGQNSLTCNKSKASR--QTFVIHK 542

Query: 191 IETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTH 250
           +E   L P  KDKVT               +    D+     +A+    +  N     TH
Sbjct: 543 LEKDNLLPNQKDKVT---------------IYENLDVTNEFHTANLSTKDNGNLCDYGTH 587

Query: 251 RNL-TSSSLNDISDKPEKDQLKNKFMKKLPRDAE 283
             L     + DI    + +   NK  KK+ R  E
Sbjct: 588 NILDLKKYVTDIQPSEQNESNINKLRKKVNRKTE 621


>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
          Length = 1261

 Score = 34.3 bits (77), Expect = 0.65
 Identities = 63/274 (22%), Positives = 101/274 (36%), Gaps = 35/274 (12%)

Query: 22  EVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEK-----KEKERISENYSDKSDIENADES 76
           EV    T+  G+   KS ++   H  KT  K K     K++ER    + + SD++  ++ 
Sbjct: 371 EVSKIVTVSTGIK-KKSNKKTNEHGMKTFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKI 429

Query: 77  SSSILKPLI---SPAAERIRFILGEEDDSPAPPQL--FTELDELLAVDGQEMEWKETARW 131
            +   +  +      AE   FI   E  +    QL    EL ++    G E   +E    
Sbjct: 430 ENRTERSDVLDGKRGAEDPGFIFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLC 489

Query: 132 IKFEEKVEQGGERWSKPHVATLSLHS-LFELRTCMEKGSIMLDREASSLPQLVEMIVDHQ 190
            K E+++    E        +LS  S  F   +  +KG   L    S   +  +  V H+
Sbjct: 490 NKKEKRITNEQEE-----TYSLSQSSGKFHQESKFDKGQNSLTCNKSKASR--QTFVIHK 542

Query: 191 IETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTH 250
           +E   L P  KDKVT               +    D+     +A+    +  N     TH
Sbjct: 543 LEKDNLLPNQKDKVT---------------IYENLDVTNEFHTANLSTKDNGNLCDYGTH 587

Query: 251 RNL-TSSSLNDISDKPEKDQLKNKFMKKLPRDAE 283
             L     + DI    + +   NK  KK+ R  E
Sbjct: 588 NILDLKKYVTDIQPSEQNESNINKLRKKVNRKTE 621


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 34.3 bits (77), Expect = 0.65
 Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)

Query: 1005 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1053
            +IP K  KKK ++KK KKK+   G+L +SD++        SD    E      +P++++E
Sbjct: 47   LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106

Query: 1054 QQPFLSDSKPSDRERSPTFLER 1075
                + + K  ++++ P   E+
Sbjct: 107  TSSSVRERKKKEKKQKPVLEEQ 128


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 34.3 bits (77), Expect = 0.65
 Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)

Query: 1005 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1053
            +IP K  KKK ++KK KKK+   G+L +SD++        SD    E      +P++++E
Sbjct: 47   LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106

Query: 1054 QQPFLSDSKPSDRERSPTFLER 1075
                + + K  ++++ P   E+
Sbjct: 107  TSSSVRERKKKEKKQKPVLEEQ 128


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 34.3 bits (77), Expect = 0.65
 Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)

Query: 1005 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1053
            +IP K  KKK ++KK KKK+   G+L +SD++        SD    E      +P++++E
Sbjct: 47   LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106

Query: 1054 QQPFLSDSKPSDRERSPTFLER 1075
                + + K  ++++ P   E+
Sbjct: 107  TSSSVRERKKKEKKQKPVLEEQ 128


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 34.3 bits (77), Expect = 0.65
 Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)

Query: 1005 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1053
            +IP K  KKK ++KK KKK+   G+L +SD++        SD    E      +P++++E
Sbjct: 47   LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106

Query: 1054 QQPFLSDSKPSDRERSPTFLER 1075
                + + K  ++++ P   E+
Sbjct: 107  TSSSVRERKKKEKKQKPVLEEQ 128


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,897,487
Number of Sequences: 37866
Number of extensions: 1985554
Number of successful extensions: 11316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 10441
Number of HSP's gapped (non-prelim): 756
length of query: 1079
length of database: 18,247,518
effective HSP length: 113
effective length of query: 966
effective length of database: 13,968,660
effective search space: 13493725560
effective search space used: 13493725560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.