BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14670375 SCG10-like-protein [Homo sapiens] (180 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14670375 SCG10-like-protein [Homo sapiens] 351 2e-97 gi|34850061 superiorcervical ganglia, neural specific 10 [Homo s... 249 1e-66 gi|21361947 stathmin-like 4 [Homo sapiens] 193 6e-50 gi|44890052 stathmin 1 isoform a [Homo sapiens] 179 9e-46 gi|44890050 stathmin 1 isoform a [Homo sapiens] 179 9e-46 gi|5031851 stathmin 1 isoform a [Homo sapiens] 179 9e-46 gi|224451142 stathmin 1 isoform b [Homo sapiens] 163 6e-41 gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 46 2e-05 gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 46 2e-05 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 45 4e-05 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 45 4e-05 gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 44 6e-05 gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 44 6e-05 gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 44 6e-05 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 44 6e-05 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 44 7e-05 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 44 7e-05 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 44 7e-05 gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 44 7e-05 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 1e-04 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 44 1e-04 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 44 1e-04 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 44 1e-04 gi|38044112 restin isoform b [Homo sapiens] 43 1e-04 gi|4506751 restin isoform a [Homo sapiens] 43 1e-04 gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 43 1e-04 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 43 2e-04 gi|24307965 UBX domain containing 2 [Homo sapiens] 43 2e-04 gi|58530840 desmoplakin isoform I [Homo sapiens] 42 2e-04 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 42 2e-04 >gi|14670375 SCG10-like-protein [Homo sapiens] Length = 180 Score = 351 bits (901), Expect = 2e-97 Identities = 180/180 (100%), Positives = 180/180 (100%) Query: 1 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKS 60 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKS Sbjct: 1 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKS 60 Query: 61 PSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHK 120 PSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHK Sbjct: 61 PSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHK 120 Query: 121 ALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 180 ALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG Sbjct: 121 ALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 180 >gi|34850061 superiorcervical ganglia, neural specific 10 [Homo sapiens] Length = 179 Score = 249 bits (635), Expect = 1e-66 Identities = 131/180 (72%), Positives = 151/180 (83%), Gaps = 1/180 (0%) Query: 1 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKS 60 MA T AYKEKMKELS+LSLICSCFY +P +Y Y DMEVKQ++KRASGQ+FE+ILK Sbjct: 1 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP 60 Query: 61 PSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHK 120 PS +S E+P + PKKKD SLEE+QK+LEAAEERRK+QEAQVLKQLAE+REHEREVL K Sbjct: 61 PSPIS-EAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQK 119 Query: 121 ALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 180 ALEENNNFS+ AEEKL KME KE REA+LAA+ ERL+EKE HAAEVRRNKE + E+SG Sbjct: 120 ALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG 179 >gi|21361947 stathmin-like 4 [Homo sapiens] Length = 216 Score = 193 bits (491), Expect = 6e-50 Identities = 113/216 (52%), Positives = 140/216 (64%), Gaps = 42/216 (19%) Query: 4 TISAYKEKMKELSVLSLICSCFYTQPHPNTVYQY-------------------------- 37 T++AYKEKMKEL ++SL CSCF P + Y+Y Sbjct: 2 TLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEGWCGRQCRRKDESQRKDSADWRERR 61 Query: 38 -------------GDMEVKQLDKRASGQSFEVILKSPS-DLSPESPMLSSPPKKKDTSLE 83 DMEV +L+K SGQSFEVILK PS D PE +S P+++D SLE Sbjct: 62 AQADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVPE--FNASLPRRRDPSLE 119 Query: 84 ELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELS 143 E+QK+LEAAEERRK QEA++LK LAE+REHEREV+ KA+EENNNF + A+EKL KME + Sbjct: 120 EIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESN 179 Query: 144 KEIREAHLAALRERLREKELHAAEVRRNKEQREEMS 179 KE REAHLAA+ ERL+EK+ HA EVR+NKE +EE S Sbjct: 180 KENREAHLAAMLERLQEKDKHAEEVRKNKELKEEAS 215 >gi|44890052 stathmin 1 isoform a [Homo sapiens] Length = 149 Score = 179 bits (455), Expect = 9e-46 Identities = 94/139 (67%), Positives = 116/139 (83%), Gaps = 3/139 (2%) Query: 39 DMEVKQLDKRASGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLEELQKRLEAAEERRK 97 D++VK+L+KRASGQ+FE+IL S S PE P+ SPPKKKD SLEE+QK+LEAAEERRK Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPL--SPPKKKDLSLEEIQKKLEAAEERRK 62 Query: 98 TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRER 157 + EA+VLKQLAE+REHE+EVL KA+EENNNFS+ AEEKL +KME +KE REA +AA ER Sbjct: 63 SHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLER 122 Query: 158 LREKELHAAEVRRNKEQRE 176 LREK+ H EVR+NKE ++ Sbjct: 123 LREKDKHIEEVRKNKESKD 141 >gi|44890050 stathmin 1 isoform a [Homo sapiens] Length = 149 Score = 179 bits (455), Expect = 9e-46 Identities = 94/139 (67%), Positives = 116/139 (83%), Gaps = 3/139 (2%) Query: 39 DMEVKQLDKRASGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLEELQKRLEAAEERRK 97 D++VK+L+KRASGQ+FE+IL S S PE P+ SPPKKKD SLEE+QK+LEAAEERRK Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPL--SPPKKKDLSLEEIQKKLEAAEERRK 62 Query: 98 TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRER 157 + EA+VLKQLAE+REHE+EVL KA+EENNNFS+ AEEKL +KME +KE REA +AA ER Sbjct: 63 SHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLER 122 Query: 158 LREKELHAAEVRRNKEQRE 176 LREK+ H EVR+NKE ++ Sbjct: 123 LREKDKHIEEVRKNKESKD 141 >gi|5031851 stathmin 1 isoform a [Homo sapiens] Length = 149 Score = 179 bits (455), Expect = 9e-46 Identities = 94/139 (67%), Positives = 116/139 (83%), Gaps = 3/139 (2%) Query: 39 DMEVKQLDKRASGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLEELQKRLEAAEERRK 97 D++VK+L+KRASGQ+FE+IL S S PE P+ SPPKKKD SLEE+QK+LEAAEERRK Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPL--SPPKKKDLSLEEIQKKLEAAEERRK 62 Query: 98 TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRER 157 + EA+VLKQLAE+REHE+EVL KA+EENNNFS+ AEEKL +KME +KE REA +AA ER Sbjct: 63 SHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLER 122 Query: 158 LREKELHAAEVRRNKEQRE 176 LREK+ H EVR+NKE ++ Sbjct: 123 LREKDKHIEEVRKNKESKD 141 >gi|224451142 stathmin 1 isoform b [Homo sapiens] Length = 174 Score = 163 bits (413), Expect = 6e-41 Identities = 87/124 (70%), Positives = 105/124 (84%), Gaps = 3/124 (2%) Query: 39 DMEVKQLDKRASGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLEELQKRLEAAEERRK 97 D++VK+L+KRASGQ+FE+IL S S PE P+ SPPKKKD SLEE+QK+LEAAEERRK Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPL--SPPKKKDLSLEEIQKKLEAAEERRK 62 Query: 98 TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRER 157 + EA+VLKQLAE+REHE+EVL KA+EENNNFS+ AEEKL +KME +KE REA +AA ER Sbjct: 63 SHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLER 122 Query: 158 LREK 161 LREK Sbjct: 123 LREK 126 >gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens] Length = 1116 Score = 46.2 bits (108), Expect = 2e-05 Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 13/135 (9%) Query: 43 KQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQ 102 +Q++K+ S Q E + +L+ S L +KKD +EEL++ L + + +E Sbjct: 800 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 859 Query: 103 VLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKE 162 + ++ + R E++V + A EK+ ++E K A L++ ++ L EKE Sbjct: 860 LAQEESARTNAEKQVEELLM---------AMEKVKQELESMK----AKLSSTQQSLAEKE 906 Query: 163 LHAAEVRRNKEQREE 177 H +R + + E Sbjct: 907 THLTNLRAERRKHLE 921 Score = 35.8 bits (81), Expect = 0.020 Identities = 35/157 (22%), Positives = 77/157 (49%), Gaps = 25/157 (15%) Query: 41 EVKQLDKRASGQSFEVILKSPS--DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKT 98 ++K L ++ S ++ K S DL + L+S KKD+ L+ L+ LE +E Sbjct: 653 DLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLK 712 Query: 99 QEAQVLK------------QLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEI 146 E+Q+ K ++++R +H L + + + S +A+ +++ +E+ KE+ Sbjct: 713 MESQLKKAHEAALEARASPEMSDRIQH----LEREITRYKDESSKAQAEVDRLLEILKEV 768 Query: 147 ------REAHLAALRERLREKELHAAEVRRNKEQREE 177 ++ +A L +++++ A + ++KEQ E+ Sbjct: 769 ENEKNDKDKKIAELERQVKDQNKKVANL-KHKEQVEK 804 Score = 33.5 bits (75), Expect = 0.10 Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 10/147 (6%) Query: 41 EVKQLDKRASGQS--FEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEER--R 96 +V+QL + S + +E + K + L E + +KDT L LQ +LE + Sbjct: 439 KVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSD 498 Query: 97 KTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIRE------AH 150 Q +VLK+ +E +L ++ + E LN K + +++ E Sbjct: 499 SKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGE 558 Query: 151 LAALRERLREKELHAAEVRRNKEQREE 177 + L++ L KE +++ E +E Sbjct: 559 IHDLKDMLDVKERKVNVLQKKIENLQE 585 Score = 32.3 bits (72), Expect = 0.23 Identities = 24/106 (22%), Positives = 54/106 (50%), Gaps = 8/106 (7%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 +K LE ++ +L + ++ +E + AERR+H EVL +++ + +E+ Sbjct: 882 EKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLE--MKQEALLAAISEKD 939 Query: 136 LN---YKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 N ++ SK+ + +AAL+ REK+ ++++ + R ++ Sbjct: 940 ANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQTQNRMKL 982 Score = 30.4 bits (67), Expect = 0.86 Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 16/109 (14%) Query: 76 KKKDTSL--EELQKRLEAAEERRKTQEAQVLKQLAER---------REHEREVLHKALEE 124 K+K+ S+ EE+ +R E A + KT+ Q + ++ + R+ E E+ + L+ Sbjct: 353 KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEI--QMLKS 410 Query: 125 NNNFSRQAEEKLNYKMELSK---EIREAHLAALRERLREKELHAAEVRR 170 N S + E+ +ME+ + + + + L+E L KE E+++ Sbjct: 411 NGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKK 459 >gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] Length = 1088 Score = 46.2 bits (108), Expect = 2e-05 Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 13/135 (9%) Query: 43 KQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQ 102 +Q++K+ S Q E + +L+ S L +KKD +EEL++ L + + +E Sbjct: 772 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 831 Query: 103 VLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKE 162 + ++ + R E++V + A EK+ ++E K A L++ ++ L EKE Sbjct: 832 LAQEESARTNAEKQVEELLM---------AMEKVKQELESMK----AKLSSTQQSLAEKE 878 Query: 163 LHAAEVRRNKEQREE 177 H +R + + E Sbjct: 879 THLTNLRAERRKHLE 893 Score = 35.8 bits (81), Expect = 0.020 Identities = 35/157 (22%), Positives = 77/157 (49%), Gaps = 25/157 (15%) Query: 41 EVKQLDKRASGQSFEVILKSPS--DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKT 98 ++K L ++ S ++ K S DL + L+S KKD+ L+ L+ LE +E Sbjct: 625 DLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLK 684 Query: 99 QEAQVLK------------QLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEI 146 E+Q+ K ++++R +H L + + + S +A+ +++ +E+ KE+ Sbjct: 685 MESQLKKAHEAALEARASPEMSDRIQH----LEREITRYKDESSKAQAEVDRLLEILKEV 740 Query: 147 ------REAHLAALRERLREKELHAAEVRRNKEQREE 177 ++ +A L +++++ A + ++KEQ E+ Sbjct: 741 ENEKNDKDKKIAELERQVKDQNKKVANL-KHKEQVEK 776 Score = 32.3 bits (72), Expect = 0.23 Identities = 24/106 (22%), Positives = 54/106 (50%), Gaps = 8/106 (7%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 +K LE ++ +L + ++ +E + AERR+H EVL +++ + +E+ Sbjct: 854 EKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLE--MKQEALLAAISEKD 911 Query: 136 LN---YKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 N ++ SK+ + +AAL+ REK+ ++++ + R ++ Sbjct: 912 ANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQTQNRMKL 954 Score = 27.3 bits (59), Expect = 7.3 Identities = 38/157 (24%), Positives = 58/157 (36%), Gaps = 54/157 (34%) Query: 76 KKKDTSL--EELQKRLEAAEERRKT-------------------------QEAQVLKQLA 108 K+K+ S+ EE+ +R E A + KT +E Q+LK Sbjct: 353 KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412 Query: 109 ERREHEREVLHKALEENNNFSRQAEEKL-NYKMELSKEIRE------------------- 148 ERE K +E + S+ + K+ K ELS++ E Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 472 Query: 149 AHLAALRERLREKELHAA-------EVRRNKEQREEM 178 H+ L+E L KE AA +R E++E M Sbjct: 473 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM 509 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 44.7 bits (104), Expect = 4e-05 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 14/117 (11%) Query: 70 MLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFS 129 MLS ++++ L E ++RL EER + QE ++L E+ E RE + E+ Sbjct: 189 MLSLLNRRQEERLREQEERLREQEERLREQE----ERLCEQEERLREQEERLREQEERLC 244 Query: 130 RQAEEKLNYKMELSKEIREAHLAALRERLREKE--LHAAEVR------RNKEQREEM 178 Q E ++ L ++ E L ERLRE+E LH E R R +EQ E + Sbjct: 245 EQEERLREHEERLCEQ--EERLCEQEERLREQEERLHEQEERLCEQEERLREQEERL 299 Score = 43.5 bits (101), Expect = 1e-04 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 10/111 (9%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKA---------LEENN 126 ++++ L E ++RL EER + QE ++ +Q REHE + + L E Sbjct: 216 REQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQE 275 Query: 127 NFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + EE+L + E +E +E L ERLRE+E E ++EE Sbjct: 276 ERLHEQEERLCEQEERLRE-QEERLCEQEERLREQEERLCEQEERLREQEE 325 Score = 39.3 bits (90), Expect = 0.002 Identities = 43/183 (23%), Positives = 79/183 (43%), Gaps = 15/183 (8%) Query: 2 ASTISAYKEKMKELSVLSLICSCFYTQ--PHPNTVYQYGDMEVKQ---LDKRASGQSFEV 56 ++T+ + + +EL+V S +Q + N++ + E K L ++ F++ Sbjct: 81 STTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKL 140 Query: 57 ILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAA--EERRKTQEAQVLKQLAERREHE 114 ++ L+PE P S ++ L+K LE+ + + + + Q+L L R+E Sbjct: 141 KNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEER 200 Query: 115 REVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQ 174 + L E R+ EE+L E + +RE ERLRE+E E + Sbjct: 201 LREQEERLREQEERLREQEERL---CEQEERLREQ-----EERLREQEERLCEQEERLRE 252 Query: 175 REE 177 EE Sbjct: 253 HEE 255 Score = 29.6 bits (65), Expect = 1.5 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 10/93 (10%) Query: 82 LEEL--QKRLEAAEERRKTQEAQVLKQLAERREHER--EVLHKALEENNNFSRQAEEKLN 137 +EEL Q+RL +ER QE L++L RE ER E+ +AL E R E+LN Sbjct: 369 VEELLEQERLRQQDERLWQQE--TLQELERLRELERMLELGWEALYEQRAEPRSGFEELN 426 Query: 138 YK----MELSKEIREAHLAALRERLREKELHAA 166 + ++L ++++E + E R E AA Sbjct: 427 NENKSTLQLEQQVKELKKSGGAEEPRGSESAAA 459 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 44.7 bits (104), Expect = 4e-05 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 11/123 (8%) Query: 62 SDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKA 121 S + +P+ P +K+ LE L+++ EA + RR+ E ++L E + E L K Sbjct: 518 SFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKV 577 Query: 122 LEENNNFSRQAEEK----------LNYKMELSKEIREAHLAALRERLREKELHAAEVRRN 171 L+ + EEK ++ K E +KE R A A +++ K++ E RR Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKA-KKKAAAKKMEEVEARRK 636 Query: 172 KEQ 174 +E+ Sbjct: 637 QEE 639 Score = 42.0 bits (97), Expect = 3e-04 Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 19/141 (13%) Query: 41 EVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQE 100 ++K+ K+ Q F I ++ + E + KKK + K++E E RRK +E Sbjct: 586 QMKEEKKKQIEQKFAQI-DEKTEKAKEERLAEEKAKKKAAA-----KKMEEVEARRKQEE 639 Query: 101 A----QVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRE 156 + L+Q E R H+ E+L K EE R+A E +K + E RE Sbjct: 640 EARRLRWLQQEEEERRHQ-ELLQKKKEEEQERLRKAAE--------AKRLAEQREQERRE 690 Query: 157 RLREKELHAAEVRRNKEQREE 177 + R ++ + RR +E+RE+ Sbjct: 691 QERREQERREQERREQERREQ 711 Score = 42.0 bits (97), Expect = 3e-04 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 11/96 (11%) Query: 83 EELQKRLEAAEER-RKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKME 141 E LQK+ E +ER RK EA K+LAE+RE ER + +E R+ +E+ + + Sbjct: 658 ELLQKKKEEEQERLRKAAEA---KRLAEQREQERREQERREQERREQERREQERREQERQ 714 Query: 142 LSKEIREAHLAALRERLR-EKELHAAE--VRRNKEQ 174 L+++ R +ERL+ E+EL E +R KEQ Sbjct: 715 LAEQERRRE----QERLQAERELQEREKALRLQKEQ 746 Score = 42.0 bits (97), Expect = 3e-04 Identities = 34/111 (30%), Positives = 59/111 (53%), Gaps = 15/111 (13%) Query: 76 KKKDTSLEELQKRLEAA-------EERRKTQEAQVLKQLAERREHEREVLHKALEENNNF 128 KKK+ E L+K EA +ERR+ + + ++ ERRE ER + L E Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER- 720 Query: 129 SRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMS 179 R+ +E+L + EL + RE L +E+L ++EL E ++ KE+++ ++ Sbjct: 721 -RREQERLQAERELQE--REKALRLQKEQL-QREL---EEKKKKEEQQRLA 764 Score = 42.0 bits (97), Expect = 3e-04 Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 7/98 (7%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 +++ E+ ++ E E+ R+ QE Q+ +Q RRE ER + L+E R +E+ Sbjct: 688 RREQERREQERREQERREQERREQERQLAEQ-ERRREQERLQAERELQEREKALRLQKEQ 746 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKE 173 L ++E K+ E ++RL E++L + ++ KE Sbjct: 747 LQRELEEKKKKEE------QQRLAERQLQEEQEKKAKE 778 Score = 37.4 bits (85), Expect = 0.007 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 10/146 (6%) Query: 34 VYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAE 93 V Q + + KQ++++ + Q E K+ + E KK +E +K+ E A Sbjct: 584 VEQMKEEKKKQIEQKFA-QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642 Query: 94 ERRKTQEAQVLKQ----LAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREA 149 R Q+ + ++ L +++E E+E L KA E R AE++ + E + +E Sbjct: 643 RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA----KRLAEQREQERREQERREQER 698 Query: 150 HLAALRER-LREKELHAAEVRRNKEQ 174 RE+ RE+E AE R +EQ Sbjct: 699 REQERREQERREQERQLAEQERRREQ 724 Score = 28.9 bits (63), Expect = 2.5 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 23/104 (22%) Query: 84 ELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELS 143 + ++R+E +E +K Q Q Q+ E+ E KA EE R AEEK K + Sbjct: 579 QARERVEQMKEEKKKQIEQKFAQIDEKTE-------KAKEE-----RLAEEKAK-KKAAA 625 Query: 144 KEIREAHLAALRE----RLR------EKELHAAEVRRNKEQREE 177 K++ E +E RLR E+ H +++ KE+ +E Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 669 >gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4 isoform 3 [Homo sapiens] Length = 1212 Score = 44.3 bits (103), Expect = 6e-05 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 4/116 (3%) Query: 67 ESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENN 126 + L + K L E QKR+E +E+R+ E Q ++ RR+ ERE + EE Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436 Query: 127 NFS----RQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 R+ EE+ + E K E +R +L E++ H +++ Q + M Sbjct: 437 RLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492 Score = 37.0 bits (84), Expect = 0.009 Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 4/148 (2%) Query: 33 TVYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAA 92 T Y+Y E ++ + I+ P + + L + K+ S E L+++ Sbjct: 319 TEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS-EALRRQQLLQ 377 Query: 93 EERRKTQEAQVLKQLAERREH--EREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAH 150 E++ + QE + LAER++ +++ + LEE R+A + + ++ + Sbjct: 378 EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRR 437 Query: 151 LAAL-RERLREKELHAAEVRRNKEQREE 177 L L R R E+E AE + + +RE+ Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQ 465 >gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 [Homo sapiens] Length = 1166 Score = 44.3 bits (103), Expect = 6e-05 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 4/116 (3%) Query: 67 ESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENN 126 + L + K L E QKR+E +E+R+ E Q ++ RR+ ERE + EE Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436 Query: 127 NFS----RQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 R+ EE+ + E K E +R +L E++ H +++ Q + M Sbjct: 437 RLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492 Score = 37.0 bits (84), Expect = 0.009 Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 4/148 (2%) Query: 33 TVYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAA 92 T Y+Y E ++ + I+ P + + L + K+ S E L+++ Sbjct: 319 TEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS-EALRRQQLLQ 377 Query: 93 EERRKTQEAQVLKQLAERREH--EREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAH 150 E++ + QE + LAER++ +++ + LEE R+A + + ++ + Sbjct: 378 EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRR 437 Query: 151 LAAL-RERLREKELHAAEVRRNKEQREE 177 L L R R E+E AE + + +RE+ Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQ 465 >gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] Length = 1320 Score = 44.3 bits (103), Expect = 6e-05 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 4/116 (3%) Query: 67 ESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENN 126 + L + K L E QKR+E +E+R+ E Q ++ RR+ ERE + EE Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436 Query: 127 NFS----RQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 R+ EE+ + E K E +R +L E++ H +++ Q + M Sbjct: 437 RLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492 Score = 40.4 bits (93), Expect = 8e-04 Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 13/117 (11%) Query: 76 KKKDTSLEELQKRLEAA------EERRKTQEAQVLKQLAERREHEREVLHKALEENNN-- 127 K++ LEE Q+R A E+RR+ QE + + ERR E E +A EE Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462 Query: 128 -----FSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMS 179 RQ EE+ + L +++ + L R RE E H R ++ ++E + Sbjct: 463 REQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQA 519 Score = 37.0 bits (84), Expect = 0.009 Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 4/148 (2%) Query: 33 TVYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAA 92 T Y+Y E ++ + I+ P + + L + K+ S E L+++ Sbjct: 319 TEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS-EALRRQQLLQ 377 Query: 93 EERRKTQEAQVLKQLAERREH--EREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAH 150 E++ + QE + LAER++ +++ + LEE R+A + + ++ + Sbjct: 378 EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRR 437 Query: 151 LAAL-RERLREKELHAAEVRRNKEQREE 177 L L R R E+E AE + + +RE+ Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQ 465 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 44.3 bits (103), Expect = 6e-05 Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 4/137 (2%) Query: 40 MEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQ 99 M+ ++ ++ G ++ +S +D + + L KKKD+ L +L R+E E+ Q Sbjct: 1095 MDTERAKRKLEGD-LKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVE-DEQLLGAQ 1152 Query: 100 EAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREA--HLAALRER 157 + +K+L R E E L +Q E ELS+ + EA A RE Sbjct: 1153 MQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREG 1212 Query: 158 LREKELHAAEVRRNKEQ 174 R++E +RR E+ Sbjct: 1213 CRKREAELGRLRRELEE 1229 Score = 37.4 bits (85), Expect = 0.007 Identities = 26/108 (24%), Positives = 53/108 (49%), Gaps = 7/108 (6%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAE-- 133 KK+ LE + LEA + + + A+ LK + + +E+ ++A E+ N +R + Sbjct: 1858 KKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLV 1917 Query: 134 EKL-----NYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQRE 176 +KL +YK + + ++A+ + R + EL AE R + + + Sbjct: 1918 DKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQ 1965 Score = 32.7 bits (73), Expect = 0.17 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 16/155 (10%) Query: 41 EVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQE 100 E+++L +A+ + + K +D + L KK L+E ++ +EAA + + E Sbjct: 1405 ELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464 Query: 101 AQVLKQLAERR----EHEREVLHKAL--EENNNFSRQAEEKLNYKMELSKEIREAH---- 150 L+ E E ER A ++ + R EE+ + E+ +E+ A Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESR 1524 Query: 151 -LAALRERLR---EKELHAAEV--RRNKEQREEMS 179 L RLR E+ L A E R NK +EE+S Sbjct: 1525 GLGTELFRLRHGHEEALEALETLKRENKNLQEEIS 1559 Score = 29.6 bits (65), Expect = 1.5 Identities = 42/155 (27%), Positives = 61/155 (39%), Gaps = 29/155 (18%) Query: 46 DKRASGQSFEVILKSPSDLSPESPMLSSPPKKKD-----TSLEELQKRLEAA---EERRK 97 + RA ++ + K DL+ L ++ T L + Q + E A EE+R Sbjct: 1653 ETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRL 1712 Query: 98 TQEAQVLKQLAERREH----EREVLHKALEENNNFSRQAEEKL-------------NYKM 140 E Q ERR E E L ALE+ R AE++L N + Sbjct: 1713 AAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGL 1772 Query: 141 ELSKEIREAHLAALRERLREKELHAAEVRRNKEQR 175 K+ EA LA L + E AA+ RR E++ Sbjct: 1773 LNQKKKLEADLAQLSGEVEE----AAQERREAEEK 1803 Score = 28.9 bits (63), Expect = 2.5 Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 19/121 (15%) Query: 67 ESPMLSSPPKKKDTSLE--ELQKRLEAAEER------RKTQEAQVLKQLAERREHEREVL 118 E +S +K D +L+ Q L AEER K Q +K+L+ER E E EV Sbjct: 923 EETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEV- 981 Query: 119 HKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 N + + + + + EL K+I + L + EKE A E + K EEM Sbjct: 982 ------NADLAARRRKLEDECTELKKDIDDLKLTLAK---AEKEKQATE-NKVKNLTEEM 1031 Query: 179 S 179 + Sbjct: 1032 A 1032 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 43.9 bits (102), Expect = 7e-05 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 KK++ E +KR E ++R++ +E + K+ E+++ ER+ + E R+ E+ Sbjct: 67 KKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRR-ERKKKKERKERER 125 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 N + K + +ER REKE E +R K ++EE Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167 Score = 43.5 bits (101), Expect = 1e-04 Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 6/136 (4%) Query: 42 VKQLDKRASGQ-SFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQE 100 VK + RA+ + + E+ + S S +S S KK+ E +KR E+ RK + Sbjct: 2 VKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKER---REREKRKREREKERKRER 58 Query: 101 AQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLRE 160 + K+ ++RE +E K +E ++ EK K + K+ RE RER ++ Sbjct: 59 GKKEKKKRKKRERGKERERKR-KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKK 117 Query: 161 KELHAAEVRRNKEQRE 176 KE E R NK++RE Sbjct: 118 KERKERE-RENKQRRE 132 Score = 37.0 bits (84), Expect = 0.009 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 14/101 (13%) Query: 77 KKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKL 136 KK+ + ++R + E +RK +E KQ ERRE ER K +E R+ + Sbjct: 60 KKEKKKRKKRERGKERERKRKERE----KQRKERREKERR---KRKKEKKKRERKQRGRR 112 Query: 137 NYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 K + ++ RE RER R+K RR K++R+E Sbjct: 113 ERKKKKERKERERENKQRRERKRKK-------RRKKKRRKE 146 Score = 34.3 bits (77), Expect = 0.059 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 13/102 (12%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 ++K+ E Q+R ++RRK + + K+ ER + ER+ + EE R+ K Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK-KRERNRK 177 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 K KE RE R++ R+KE RR K++R++ Sbjct: 178 ERKKERERKERRE------RKKERKKE------RRKKKERKK 207 Score = 33.5 bits (75), Expect = 0.10 Identities = 30/140 (21%), Positives = 61/140 (43%), Gaps = 4/140 (2%) Query: 38 GDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRK 97 G E K+ KR G+ E K E +KK+ E ++R E ++K Sbjct: 59 GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQR-GRRERKKK 117 Query: 98 TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRER 157 + + ++ +RRE +R+ K ++ R+ E++ + K+ ++ RER Sbjct: 118 KERKERERENKQRRERKRK---KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174 Query: 158 LREKELHAAEVRRNKEQREE 177 R++ E + +E+++E Sbjct: 175 NRKERKKERERKERRERKKE 194 Score = 33.1 bits (74), Expect = 0.13 Identities = 18/92 (19%), Positives = 42/92 (45%) Query: 86 QKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKE 145 Q+ E +ERR+ ++ + ++ +RE ++ K + R+ + K K + Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90 Query: 146 IREAHLAALRERLREKELHAAEVRRNKEQREE 177 +E ++ RE++ R+ K++R+E Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKE 122 Score = 31.2 bits (69), Expect = 0.50 Identities = 25/114 (21%), Positives = 51/114 (44%), Gaps = 9/114 (7%) Query: 64 LSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALE 123 L+ E M+S K + E +++ E E ++ +E + + R+ ER K Sbjct: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKRERE------KERKRERGKKEKKKR 66 Query: 124 ENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + ++ E K + + KE RE R+R +EK+ + R +E++++ Sbjct: 67 KKRERGKERERKRKEREKQRKERREKER---RKRKKEKKKRERKQRGRRERKKK 117 Score = 29.6 bits (65), Expect = 1.5 Identities = 22/101 (21%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Query: 77 KKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKL 136 +++ ++ +K E ++R+ ++ + ++ R+E +RE + E R+ EE+ Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE-KERGKRERKRKKRKKEER- 168 Query: 137 NYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 K E +++ R+ R R+KE E R+ KE++++ Sbjct: 169 EKKRERNRKERKKERERKERRERKKE-RKKERRKKKERKKD 208 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 43.9 bits (102), Expect = 7e-05 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 5/122 (4%) Query: 58 LKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREV 117 +K P +S + + +K+ K E ERRK + Q RRE ER+ Sbjct: 85 IKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE---QDKARREWERQK 141 Query: 118 LHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + E++ R E+L K E +++RE + +E+E A E R+ +E R E Sbjct: 142 RREMAREHSRRERDRLEQLERKRERERKMREQQKE--QREQKERERRAEERRKEREARRE 199 Query: 178 MS 179 +S Sbjct: 200 VS 201 Score = 35.0 bits (79), Expect = 0.035 Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 5/80 (6%) Query: 84 ELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALE--ENNNFSRQAEEKLNYKME 141 E QKR E A E + +E L+QL +RE ER++ + E E R+AEE+ + E Sbjct: 138 ERQKRREMAREHSR-RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-RKERE 195 Query: 142 LSKEIREAHLAALRERLREK 161 +E+ AH +RE +K Sbjct: 196 ARREV-SAHHRTMREDYSDK 214 Score = 29.6 bits (65), Expect = 1.5 Identities = 18/68 (26%), Positives = 35/68 (51%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 +++ LE+L+++ E + R+ Q+ Q ++ ERR ER +A E + R E Sbjct: 151 RRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 210 Query: 136 LNYKMELS 143 + K++ S Sbjct: 211 YSDKVKAS 218 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 43.9 bits (102), Expect = 7e-05 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 5/122 (4%) Query: 58 LKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREV 117 +K P +S + + +K+ K E ERRK + Q RRE ER+ Sbjct: 51 IKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE---QDKARREWERQK 107 Query: 118 LHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + E++ R E+L K E +++RE + +E+E A E R+ +E R E Sbjct: 108 RREMAREHSRRERDRLEQLERKRERERKMREQQKE--QREQKERERRAEERRKEREARRE 165 Query: 178 MS 179 +S Sbjct: 166 VS 167 Score = 35.0 bits (79), Expect = 0.035 Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 5/80 (6%) Query: 84 ELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALE--ENNNFSRQAEEKLNYKME 141 E QKR E A E + +E L+QL +RE ER++ + E E R+AEE+ + E Sbjct: 104 ERQKRREMAREHSR-RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-RKERE 161 Query: 142 LSKEIREAHLAALRERLREK 161 +E+ AH +RE +K Sbjct: 162 ARREV-SAHHRTMREDYSDK 180 Score = 29.6 bits (65), Expect = 1.5 Identities = 18/68 (26%), Positives = 35/68 (51%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 +++ LE+L+++ E + R+ Q+ Q ++ ERR ER +A E + R E Sbjct: 117 RRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 176 Query: 136 LNYKMELS 143 + K++ S Sbjct: 177 YSDKVKAS 184 >gi|210032790 hypothetical protein LOC27146 [Homo sapiens] Length = 1060 Score = 43.9 bits (102), Expect = 7e-05 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 9/130 (6%) Query: 55 EVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHE 114 +V+LK SD P L S K+K + ++ L++ ++ + + + Q +Q+ + L + + Sbjct: 567 KVLLKEGSD---PQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNY 623 Query: 115 REVLHKALE----ENNNFSRQAEEKLNYKMELSKEIREAHLAALR--ERLREKELHAAEV 168 RE L + E R+ +E + ++ +H ALR E+ R +EL A E Sbjct: 624 REDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEE 683 Query: 169 RRNKEQREEM 178 R KE + Sbjct: 684 RLKKESSHSL 693 Score = 31.2 bits (69), Expect = 0.50 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 19/102 (18%) Query: 79 DTSLEELQKRLEAAEERRKTQEAQV-------LKQLAERREHEREVLHKALEENNNFSRQ 131 D E+LQ+ L+ ++ +AQ+ L+ L + R E + + L++ ++ S Q Sbjct: 635 DLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQ 694 Query: 132 A------------EEKLNYKMELSKEIREAHLAALRERLREK 161 EEK +++ +E +A A L E LR++ Sbjct: 695 IQHQTHRLELQALEEKARQELQEERERMQAQQALLLESLRQE 736 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 43.5 bits (101), Expect = 1e-04 Identities = 40/170 (23%), Positives = 79/170 (46%), Gaps = 31/170 (18%) Query: 32 NTVYQYGDMEVKQLDKRASGQSFEV---------ILKSPSDLSPESPMLSSPPKKKDTSL 82 +T ++ D +++L K S E+ + K ++L + P+ S + ++ Sbjct: 189 STRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNV 248 Query: 83 EELQKRLEAA-----EERRKTQEAQVLKQLAERREHEREV---------LHKALEENNNF 128 +EL+++LE A + + T + ++ +Q E RE E+++ + L E Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 308 Query: 129 SRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 R+ EEK+ ++ E K +RE + LRE+E E + +EQ E+M Sbjct: 309 MREQEEKM-WRQE--KRLREQ-----EKELREQEKELREQKELREQEEQM 350 Score = 40.0 bits (92), Expect = 0.001 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Query: 77 KKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVL-HKALEENNNFSRQAEEK 135 +++ L E + ++ EE+ QE ++ +Q E RE E+E+ K L E ++ EEK Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + + E +E +E + ERL E+E E + +EE Sbjct: 357 MWEQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397 Score = 37.7 bits (86), Expect = 0.005 Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAE-- 133 ++++ L E +K L +E R+ +E Q+ E+ E E K E+ RQ E Sbjct: 324 REQEKELREQEKELREQKELREQEE-----QMQEQEEKMWEQEEKMREQEEKMWRQEERL 378 Query: 134 ---EKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 EK + E +E + ERLREKE E + EQ E+M Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKM 426 Score = 34.3 bits (77), Expect = 0.059 Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 9/120 (7%) Query: 67 ESPMLSSPPKKKDTS--LEELQKRLEAAEERRKTQEA---QVLKQLAERREHEREVLHKA 121 E M K +D + E +RL EER + QE QV K E++ E+E + Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD 441 Query: 122 LEENNNFS---RQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 EE R+ E+K+ + E +E +E + E + E+E + +R EQ+E++ Sbjct: 442 QEEKMQEEERIREREKKMREEEETMRE-QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500 Score = 33.1 bits (74), Expect = 0.13 Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 11/103 (10%) Query: 82 LEELQKRLEAAEERRKTQEAQVLKQLAER-REHEREVLHKALEENNNFSRQAEEKL---- 136 +E++++ + E+ +KT++ + Q ER RE E++ + E R+ EEK+ Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK-----MREEEETMREQEEKMQKQE 477 Query: 137 -NYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 N + KE ++ L +E+L E+E + + EQ E++ Sbjct: 478 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520 Score = 32.7 bits (73), Expect = 0.17 Identities = 21/106 (19%), Positives = 51/106 (48%), Gaps = 5/106 (4%) Query: 77 KKDTSLEELQKRLEAAEERRKTQEAQVLKQ-----LAERREHEREVLHKALEENNNFSRQ 131 +++ L E +K++ E++ + QE ++ +Q E R E+E + + +E+ + Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432 Query: 132 AEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 E++ + + K E + +++RE+E E +++EE Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478 Score = 32.3 bits (72), Expect = 0.23 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 4/105 (3%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEA--QVLKQLAERREHEREVLHKALEENNNFSRQAE 133 ++ + +E +K+ EE+ + +E + K++ E E RE K E+ Q E Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ-E 623 Query: 134 EKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 EK+ ++ E + +E + E++ E+E E +R EQ+E++ Sbjct: 624 EKM-WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667 Score = 31.2 bits (69), Expect = 0.50 Identities = 28/139 (20%), Positives = 60/139 (43%), Gaps = 3/139 (2%) Query: 39 DMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKT 98 + E K+ ++ + E + + E + K +D Q++ +E+ + Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541 Query: 99 QEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERL 158 QE Q+ +Q + R+ E+++ + EE Q +EK + E K E + +++ Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQ--EERMEKKTQEQEKKTWDQE-EKMREEERMREREKKM 598 Query: 159 REKELHAAEVRRNKEQREE 177 RE+E E +++EE Sbjct: 599 REEEEMMREQEEKMQEQEE 617 Score = 27.7 bits (60), Expect = 5.6 Identities = 25/109 (22%), Positives = 56/109 (51%), Gaps = 14/109 (12%) Query: 77 KKDTSLEELQKRLEAAEERRKTQEAQVLKQ--LAER----REHEREVLHKALEENNNFSR 130 +++ ++E ++++ EE+ QE ++ +Q L E+ EHE+ ++E Sbjct: 628 EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK------MQEQEKMQE 681 Query: 131 QAEEKLNYKMELSKEIREAHLAAL-RERLREKELHAAEVRRNKEQREEM 178 Q EEK+ + ++ K+ +E +E++RE+E ++ +E+ E M Sbjct: 682 Q-EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM 729 Score = 27.3 bits (59), Expect = 7.3 Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 82 LEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKL---NY 138 ++E ++++ EE+ + QE ++ R+ + + E R E+K+ Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565 Query: 139 KMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 +ME + +E E++RE+E ++ +E+ E M Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605 Score = 27.3 bits (59), Expect = 7.3 Identities = 20/106 (18%), Positives = 49/106 (46%), Gaps = 4/106 (3%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQA--- 132 ++++ + E ++++ E++ QE ++ K+ E+ + + K EE R+ Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599 Query: 133 -EEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 EE++ + E + +E + E++ E+E E ++EE Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645 Score = 27.3 bits (59), Expect = 7.3 Identities = 19/106 (17%), Positives = 49/106 (46%), Gaps = 1/106 (0%) Query: 76 KKKDTSLEELQKRLEAAEERRK-TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEE 134 +KK E++++ E +K +E +++++ E+ + + E + + EE + E Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759 Query: 135 KLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 180 + E + + E+++E+E + + ++Q E+M G Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRG 805 Score = 26.9 bits (58), Expect = 9.5 Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 8/96 (8%) Query: 86 QKRLEAAEER----RKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKME 141 Q+RL +E+ K QE + +++ E + E+E + K +E ++ ++ + E Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQE-QEEKIWEQEKMEKKTQEQ---EKKTWDQEKMREE 712 Query: 142 LSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 S RE + E +RE+E E +++EE Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 43.5 bits (101), Expect = 1e-04 Identities = 52/162 (32%), Positives = 70/162 (43%), Gaps = 42/162 (25%) Query: 50 SGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLE----------------ELQKRLEAA 92 SG VI + D PE P+L ++ + L EL+KR +A Sbjct: 313 SGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQAL 372 Query: 93 -EERRKTQE--AQVLKQLAERREHERE--------VLHKALEENNNFSRQAEEKLNYKME 141 E++RK QE AQ+ + ER+E ER+ L K LE+ RQ EE E Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREE------E 426 Query: 142 LSKEIREAHLAALRERLREKELHAAEVR-------RNKEQRE 176 KEI E AA RE R+++L R RNKEQ + Sbjct: 427 RRKEI-ERREAAKRELERQRQLEWERNRRQELLNQRNKEQED 467 Score = 32.7 bits (73), Expect = 0.17 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 K+++ + EL+K+ E A+ R + ++ Q L+ + + EH+R + L E R+ K Sbjct: 633 KEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRP---RKLHEEEKLKREESVK 689 Query: 136 LNYKMELSKEIREAHLAALRERLRE 160 E K+ + L L + +E Sbjct: 690 KKDGEEKGKQEAQDKLGRLFHQHQE 714 Score = 30.8 bits (68), Expect = 0.66 Identities = 23/95 (24%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Query: 85 LQKRLEAAEERRKTQEAQV-LKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELS 143 L +L+ ++ +++ V LK+ E +E R+ L L+E +R ++++ Sbjct: 548 LNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQL 607 Query: 144 KEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 KE+RE H +++L++++ AE + KEQ ++ Sbjct: 608 KELREIH---NKQQLQKQKSMEAERLKQKEQERKI 639 Score = 29.6 bits (65), Expect = 1.5 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 77 KKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHERE---VLHKALEENNNFSRQAE 133 +K S+E +RL+ E+ RK E + K+ A+RR ER+ + H E+ + R+ Sbjct: 620 QKQKSMEA--ERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLH 677 Query: 134 EKLNYKMELS 143 E+ K E S Sbjct: 678 EEEKLKREES 687 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 43.5 bits (101), Expect = 1e-04 Identities = 52/162 (32%), Positives = 70/162 (43%), Gaps = 42/162 (25%) Query: 50 SGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLE----------------ELQKRLEAA 92 SG VI + D PE P+L ++ + L EL+KR +A Sbjct: 313 SGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQAL 372 Query: 93 -EERRKTQE--AQVLKQLAERREHERE--------VLHKALEENNNFSRQAEEKLNYKME 141 E++RK QE AQ+ + ER+E ER+ L K LE+ RQ EE E Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREE------E 426 Query: 142 LSKEIREAHLAALRERLREKELHAAEVR-------RNKEQRE 176 KEI E AA RE R+++L R RNKEQ + Sbjct: 427 RRKEI-ERREAAKRELERQRQLEWERNRRQELLNQRNKEQED 467 Score = 32.7 bits (73), Expect = 0.17 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 K+++ + EL+K+ E A+ R + ++ Q L+ + + EH+R + L E R+ K Sbjct: 633 KEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRP---RKLHEEEKLKREESVK 689 Query: 136 LNYKMELSKEIREAHLAALRERLRE 160 E K+ + L L + +E Sbjct: 690 KKDGEEKGKQEAQDKLGRLFHQHQE 714 Score = 30.8 bits (68), Expect = 0.66 Identities = 23/95 (24%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Query: 85 LQKRLEAAEERRKTQEAQV-LKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELS 143 L +L+ ++ +++ V LK+ E +E R+ L L+E +R ++++ Sbjct: 548 LNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQL 607 Query: 144 KEIREAHLAALRERLREKELHAAEVRRNKEQREEM 178 KE+RE H +++L++++ AE + KEQ ++ Sbjct: 608 KELREIH---NKQQLQKQKSMEAERLKQKEQERKI 639 Score = 29.6 bits (65), Expect = 1.5 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 77 KKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHERE---VLHKALEENNNFSRQAE 133 +K S+E +RL+ E+ RK E + K+ A+RR ER+ + H E+ + R+ Sbjct: 620 QKQKSMEA--ERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLH 677 Query: 134 EKLNYKMELS 143 E+ K E S Sbjct: 678 EEEKLKREES 687 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 43.5 bits (101), Expect = 1e-04 Identities = 30/96 (31%), Positives = 53/96 (55%), Gaps = 9/96 (9%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVL--KQLAERREHEREVLHKALEE--NNNFSRQ 131 K++ +EE Q+ LE EER+K ++ Q L K L + +E ER + +E N N + Sbjct: 175 KRRQQEVEERQRMLE--EERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEE 232 Query: 132 AEEKLNYKMELSKE---IREAHLAALRERLREKELH 164 +K+ + + SKE I+E +L +++R R + L+ Sbjct: 233 GRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLN 268 Score = 32.7 bits (73), Expect = 0.17 Identities = 32/127 (25%), Positives = 50/127 (39%), Gaps = 7/127 (5%) Query: 51 GQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAER 110 G+ F+ S E PK + SLEEL + +A EE A+ + + Sbjct: 113 GKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEE------AEAKPKFLSK 166 Query: 111 REHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRR 170 E E E L + +E R EE+ K + +++ L +ER R + E Sbjct: 167 AEREAEALKRRQQEVEERQRMLEEE-RKKRKQFQDLGRKMLEDPQERERRERRERMERET 225 Query: 171 NKEQREE 177 N + EE Sbjct: 226 NGNEDEE 232 >gi|38044112 restin isoform b [Homo sapiens] Length = 1392 Score = 43.1 bits (100), Expect = 1e-04 Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 28/202 (13%) Query: 1 MASTISAYKE---KMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLD----KRASGQS 53 M T++ +E K+KEL VL C+ T+ N Q E K LD ++AS + Sbjct: 682 MEDTLNKLQEAEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDALRKASSEG 740 Query: 54 FEVILKSPSDL--------------SPESPMLSSPPKK---KDTSLEELQKRLEAAEERR 96 + K L + ES SS ++ ++ L LQ+ L + + Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 800 Query: 97 KT--QEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAAL 154 +T +E Q+LK+ E + ++++E N Q EE+ N +++RE +LA + Sbjct: 801 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE-NLADM 859 Query: 155 RERLREKELHAAEVRRNKEQRE 176 + REK+ ++ + KE+ E Sbjct: 860 EAKFREKDEREEQLIKAKEKLE 881 Score = 39.7 bits (91), Expect = 0.001 Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 13/117 (11%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQL--AERREHEREVLHKALEEN----NNFS 129 K+K+ SLE ++ +L+ AE++ + L +L AE + E EVL E +NF+ Sbjct: 658 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFT 717 Query: 130 RQ---AEEKLNYKMELSKEIRE--AHLAALRERLR--EKELHAAEVRRNKEQREEMS 179 Q EEKL L K E + + LR++L EK++ E+ +N E + S Sbjct: 718 SQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASS 774 Score = 35.8 bits (81), Expect = 0.020 Identities = 32/142 (22%), Positives = 61/142 (42%), Gaps = 6/142 (4%) Query: 42 VKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTS---LEELQKRLEAAEERRKT 98 ++ + +A E K + LS KK +TS +EL+ R E A KT Sbjct: 933 IEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKT 992 Query: 99 QEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAH--LAALRE 156 + ++L+ L + + L A EEN+ ++ EE L + + +K + A + + + Sbjct: 993 KHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE-LRKQADKAKAAQTAEDAMQIMEQ 1051 Query: 157 RLREKELHAAEVRRNKEQREEM 178 +EK A + K+ ++ Sbjct: 1052 MTKEKTETLASLEDTKQTNAKL 1073 Score = 34.7 bits (78), Expect = 0.045 Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 13/136 (9%) Query: 57 ILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHERE 116 I+K D S + ++ + K+ +EELQ +L A E + + + + ++E Sbjct: 887 IMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQE 946 Query: 117 VLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRN----- 171 K EE R+ + L KME S + A E + E+ +N Sbjct: 947 AAKKHEEEKKELERKLSD-LEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTL 1005 Query: 172 -------KEQREEMSG 180 K REE SG Sbjct: 1006 LDTEDKLKGAREENSG 1021 >gi|4506751 restin isoform a [Homo sapiens] Length = 1427 Score = 43.1 bits (100), Expect = 1e-04 Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 28/202 (13%) Query: 1 MASTISAYKE---KMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLD----KRASGQS 53 M T++ +E K+KEL VL C+ T+ N Q E K LD ++AS + Sbjct: 717 MEDTLNKLQEAEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDALRKASSEG 775 Query: 54 FEVILKSPSDL--------------SPESPMLSSPPKK---KDTSLEELQKRLEAAEERR 96 + K L + ES SS ++ ++ L LQ+ L + + Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 835 Query: 97 KT--QEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAAL 154 +T +E Q+LK+ E + ++++E N Q EE+ N +++RE +LA + Sbjct: 836 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE-NLADM 894 Query: 155 RERLREKELHAAEVRRNKEQRE 176 + REK+ ++ + KE+ E Sbjct: 895 EAKFREKDEREEQLIKAKEKLE 916 Score = 39.7 bits (91), Expect = 0.001 Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 13/117 (11%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQL--AERREHEREVLHKALEEN----NNFS 129 K+K+ SLE ++ +L+ AE++ + L +L AE + E EVL E +NF+ Sbjct: 693 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFT 752 Query: 130 RQ---AEEKLNYKMELSKEIRE--AHLAALRERLR--EKELHAAEVRRNKEQREEMS 179 Q EEKL L K E + + LR++L EK++ E+ +N E + S Sbjct: 753 SQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASS 809 Score = 35.8 bits (81), Expect = 0.020 Identities = 32/142 (22%), Positives = 61/142 (42%), Gaps = 6/142 (4%) Query: 42 VKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTS---LEELQKRLEAAEERRKT 98 ++ + +A E K + LS KK +TS +EL+ R E A KT Sbjct: 968 IEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKT 1027 Query: 99 QEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAH--LAALRE 156 + ++L+ L + + L A EEN+ ++ EE L + + +K + A + + + Sbjct: 1028 KHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE-LRKQADKAKAAQTAEDAMQIMEQ 1086 Query: 157 RLREKELHAAEVRRNKEQREEM 178 +EK A + K+ ++ Sbjct: 1087 MTKEKTETLASLEDTKQTNAKL 1108 Score = 34.7 bits (78), Expect = 0.045 Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 13/136 (9%) Query: 57 ILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHERE 116 I+K D S + ++ + K+ +EELQ +L A E + + + + ++E Sbjct: 922 IMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQE 981 Query: 117 VLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRN----- 171 K EE R+ + L KME S + A E + E+ +N Sbjct: 982 AAKKHEEEKKELERKLSD-LEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTL 1040 Query: 172 -------KEQREEMSG 180 K REE SG Sbjct: 1041 LDTEDKLKGAREENSG 1056 Score = 27.3 bits (59), Expect = 7.3 Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 24/130 (18%) Query: 63 DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQ-------VLKQLAERREHER 115 +L + L + + D EL +LE EE+RK ++ Q + K E + Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLE--EEKRKVEDLQFRVEEESITKGDLETQTKLE 462 Query: 116 EVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKEL---------HAA 166 K LE++ F + +K L +E+ + +A + E+ R EL A Sbjct: 463 HARIKELEQSLLFEKTKADK------LQRELEDTRVATVSEKSRIMELEKDLALRVQEVA 516 Query: 167 EVRRNKEQRE 176 E+RR E + Sbjct: 517 ELRRRLESNK 526 >gi|134152708 arginine and glutamate rich 1 [Homo sapiens] Length = 273 Score = 43.1 bits (100), Expect = 1e-04 Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 19/126 (15%) Query: 72 SSPPKKKD---------TSLEELQKRLEAA-----EERRKTQEAQVLKQLAER---REHE 114 SSPP + D +SL+E QKR E E +RK ++ ++ ++L E R E Sbjct: 76 SSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVE 135 Query: 115 REVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKE- 173 V + EE + E ++ ++E +K I E L ER R+ EL A + R +E Sbjct: 136 ELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEER 195 Query: 174 -QREEM 178 +REE+ Sbjct: 196 AKREEL 201 Score = 40.4 bits (93), Expect = 8e-04 Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 22/114 (19%) Query: 76 KKKDTSLEELQKRLEAA---------EERRKTQEAQVLKQLAERREH--EREVLHKALEE 124 K+KD E+ +R+E A EE + ++A++ Q A E +RE L + LEE Sbjct: 148 KRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEE 207 Query: 125 NNNFSRQAEEKL-NYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 NN +A+ KL ++ + +E R+ H ER++ E R ++Q+EE Sbjct: 208 NNRKIAEAQAKLAEEQLRIVEEQRKIH----EERMK------LEQERQRQQKEE 251 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Query: 39 DMEVKQLDKRASGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLEELQKRLEAAEERRK 97 D E K+ D+ G +I + S+L+ P S P KKK E++ +R A Sbjct: 197 DEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPY 256 Query: 98 TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRER 157 + E E +R+++ + + + + ++ EE+ K + +EI + RER Sbjct: 257 PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERER 316 Query: 158 LREKELHAAEVRRNKEQREE 177 RE+E E R +E+ E Sbjct: 317 ERERERRERERERERERERE 336 Score = 37.4 bits (85), Expect = 0.007 Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 16/115 (13%) Query: 73 SPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQA 132 S K +D E ++R E ER + +E + ++ RE ERE ++ + Sbjct: 384 SREKSRDRERERERER-ERERERERERERERERERERERERERE------KDKKRDREED 436 Query: 133 EEKLNYKMELSKEIREAHLAALRERLREKEL--------HAAEVRRNKEQREEMS 179 EE + +L +++RE AA +ERL+ E+ + E R +E+R EM+ Sbjct: 437 EEDAYERRKLERKLREKE-AAYQERLKNWEIRERKKTREYEKEAEREEERRREMA 490 Score = 33.5 bits (75), Expect = 0.10 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 4/97 (4%) Query: 84 ELQKRLEAAEERRKTQEAQVLKQLAERREHEREV---LHKALEENNNFSRQAEEKLNYKM 140 E +K E ER + ++ K+ R+ ER+ ++ + N + SR E+ + + Sbjct: 334 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER 393 Query: 141 ELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 E +E RE RER RE+E R + ++++ Sbjct: 394 ERERE-REREREREREREREREREREREREREREKDK 429 Score = 33.5 bits (75), Expect = 0.10 Identities = 22/70 (31%), Positives = 33/70 (47%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 K++ LEE+++RL A E Q ++Q AERR + EE ++ EEK Sbjct: 537 KREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEK 596 Query: 136 LNYKMELSKE 145 ME +E Sbjct: 597 REEPMEEEEE 606 Score = 31.6 bits (70), Expect = 0.38 Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 15/107 (14%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 ++K+ + +E K E ER+KT+E + + AER E R + K + F ++ Sbjct: 451 REKEAAYQERLKNWEI-RERKKTREYE---KEAEREEERRREMAKEAKRLKEFLEDYDDD 506 Query: 136 LNYKMELSKEIREAHLAALRERLR--EKELHAAEV--RRNKEQREEM 178 + + + +AL++RLR EKE+ A E +R KE+ EE+ Sbjct: 507 RD-------DPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI 546 Score = 30.0 bits (66), Expect = 1.1 Identities = 28/123 (22%), Positives = 50/123 (40%), Gaps = 10/123 (8%) Query: 55 EVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHE 114 ++I + S L KK+ +E++K E R+ + ERRE E Sbjct: 275 DLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER--------ERRERE 326 Query: 115 REVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQ 174 RE + E R+ E + + + +KE R+ R+R R++E + + Sbjct: 327 RE-REREREREKEKERERERERDRDRDRTKE-RDRDRDRERDRDRDRERSSDRNKDRSRS 384 Query: 175 REE 177 RE+ Sbjct: 385 REK 387 Score = 29.3 bits (64), Expect = 1.9 Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 28/121 (23%) Query: 84 ELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEEN---------NNFSRQAEE 134 E ++ + +R + +E ++ ER+ E+E ++ +N + ++AE Sbjct: 422 EREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAER 481 Query: 135 KLNYKMELSKEIREA-----------------HLAALRERL--REKELHAAEVRRNKEQR 175 + + E++KE + +AL++RL REKE+ A E R +E+ Sbjct: 482 EEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE 541 Query: 176 E 176 E Sbjct: 542 E 542 >gi|24307965 UBX domain containing 2 [Homo sapiens] Length = 508 Score = 42.7 bits (99), Expect = 2e-04 Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 14/109 (12%) Query: 74 PPKKKDTSLEELQKRLEAA-EERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQA 132 P + + +E L K+LE EE+RK +E + +K+ ERR+ +E+L ++ R+ Sbjct: 191 PAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEML--------DYKRKQ 242 Query: 133 EEKLNYKMELSKEIREAHLAALRERLR-----EKELHAAEVRRNKEQRE 176 EE+L +M + +A A RER++ ++ AA + KE+ E Sbjct: 243 EEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVE 291 >gi|58530840 desmoplakin isoform I [Homo sapiens] Length = 2871 Score = 42.4 bits (98), Expect = 2e-04 Identities = 30/120 (25%), Positives = 58/120 (48%), Gaps = 7/120 (5%) Query: 59 KSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKT--QEAQVLKQLAERREHERE 116 +S DL + +L ++K + EEL++ E R+ QE + +KQ R EH Sbjct: 1628 RSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEH--- 1684 Query: 117 VLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQRE 176 KA+E+ + +++ ++ L++ + + HL L E LR L ++RR + + + Sbjct: 1685 -FQKAIEDKSRSLNESKIEIERLQSLTENLTKEHL-MLEEELRNLRLEYDDLRRGRSEAD 1742 Score = 29.3 bits (64), Expect = 1.9 Identities = 22/97 (22%), Positives = 48/97 (49%), Gaps = 11/97 (11%) Query: 89 LEAAEERRKTQEAQVLK-----QLAERREHE----REVLHKALEENNNFSRQAEEKLNYK 139 L+A E+RR+ +E + + ++ ++++H ++V+ + E+N + EE Sbjct: 1261 LQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTI 1320 Query: 140 MELSKEIR--EAHLAALRERLREKELHAAEVRRNKEQ 174 + +KEI +A +R E E ++VR N ++ Sbjct: 1321 QDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDE 1357 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 42.4 bits (98), Expect = 2e-04 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Query: 78 KDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLN 137 K+ +E +KR E E RK +E + ++ ER++ ER+ + + EE ++ E K Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER----KEKERKER 186 Query: 138 YKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMS 179 K E +++ R+ R R+KE E R+ + Q++ + Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228 Score = 40.0 bits (92), Expect = 0.001 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 8/109 (7%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQE-----AQVLKQLAERREH--EREVLHKALEENNNF 128 +K++ EE ++R EER K +E + KQ+ E+ E E+E + E N Sbjct: 135 RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194 Query: 129 SRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 R+ E + + E KE R+ +ER ++++ + E R K +R+E Sbjct: 195 ERKKERERKERRERKKE-RKKKEERKKERQKDRQTNWREKERGKRERKE 242 Score = 38.1 bits (87), Expect = 0.004 Identities = 24/102 (23%), Positives = 46/102 (45%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 +KK E + E E RK + + ++ ER++ ERE + E +Q EK Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + E ++ R+ +ER +E+E R+ + +++E Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216 Score = 37.4 bits (85), Expect = 0.007 Identities = 25/103 (24%), Positives = 52/103 (50%), Gaps = 5/103 (4%) Query: 80 TSLEELQKRLEAAEERRKTQEAQVLKQLAER----REHEREVLHKALEENNNFSRQAEEK 135 + + E ++ +E +E +K +E++ K+ ER RE E+E + ++ R+ EE+ Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95 Query: 136 LNYKMELSKEIREAHLAALRERLREKEL-HAAEVRRNKEQREE 177 K KE +E R++ +KE ++ + +E++EE Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE 138 Score = 37.4 bits (85), Expect = 0.007 Identities = 23/102 (22%), Positives = 46/102 (45%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 +KK+ + + +E RK +E + ++ E RE ERE + E + EE+ Sbjct: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + + K+ +ER R++ + R+ KE+R++ Sbjct: 179 KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKK 220 Score = 33.5 bits (75), Expect = 0.10 Identities = 25/109 (22%), Positives = 52/109 (47%), Gaps = 7/109 (6%) Query: 76 KKKDTSLEELQKRLEAAEERR-------KTQEAQVLKQLAERREHEREVLHKALEENNNF 128 +K++ EE +KR + ++ R K +E + ++ ER+E ER+ + E Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162 Query: 129 SRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 ++ E K + E ++ +E RER R++ E + +E+++E Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211 Score = 33.1 bits (74), Expect = 0.13 Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 5/105 (4%) Query: 76 KKKDTSLEELQKR---LEAAEER-RKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQ 131 +KK+ E +KR E ER +K ++ + K+ ER++ RE +K EE ++ Sbjct: 59 RKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKK 118 Query: 132 AEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQRE 176 +++ + KE RE RE +E+E E + +E++E Sbjct: 119 EKKERGRTSKEGKE-RERKEERKREERKERERKKEEREKERERKE 162 Score = 33.1 bits (74), Expect = 0.13 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 11/101 (10%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 ++K E+ K E E+R+K ++ + + E +E ER+ K EE R+ EE+ Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR-EERKERERKKEER 154 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQRE 176 + ++ RE R+++ EKE E R+ KE++E Sbjct: 155 EKERERKERKKRE------RKQVGEKE----EERKEKERKE 185 Score = 32.7 bits (73), Expect = 0.17 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 7/102 (6%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 KK + EE +++ E+ K E + ++ E++E R E ++ E K Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145 Query: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 + E KE RE RER K+ +V +E+R+E Sbjct: 146 ---ERERKKEEREKE----RERKERKKRERKQVGEKEEERKE 180 Score = 32.0 bits (71), Expect = 0.29 Identities = 22/105 (20%), Positives = 47/105 (44%) Query: 73 SPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQA 132 S KK+ E+ ++ E +R + ++ + ++ E RE ++ K +E ++ Sbjct: 57 SERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116 Query: 133 EEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREE 177 +++ + SKE +E R+R KE + R KE+ + Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161 Score = 31.2 bits (69), Expect = 0.50 Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 13/112 (11%) Query: 76 KKKDTSLEELQKRLEAAEERRKTQEAQ--------VLKQLAERREHEREVLHKALEENNN 127 +K+ E +++ E E ++ +E + ++ ER++ ERE + E+ N Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN- 106 Query: 128 FSRQAEEKLNYKMELSKEI-REAHLAALRERLREKELHAAEVR-RNKEQREE 177 ++ EEK K + KE R + RER E++ + R R KE+RE+ Sbjct: 107 --KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.123 0.323 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,692,400 Number of Sequences: 37866 Number of extensions: 306528 Number of successful extensions: 5525 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 306 Number of HSP's successfully gapped in prelim test: 654 Number of HSP's that attempted gapping in prelim test: 2730 Number of HSP's gapped (non-prelim): 2664 length of query: 180 length of database: 18,247,518 effective HSP length: 96 effective length of query: 84 effective length of database: 14,612,382 effective search space: 1227440088 effective search space used: 1227440088 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.