Guide to the Human Genome
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Search of human proteins with 14670352

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14670352 general transcription factor II, i isoform 2 [Homo
sapiens]
         (978 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14670352 general transcription factor II, i isoform 2 [Homo s...  1955   0.0  
gi|14670350 general transcription factor II, i isoform 1 [Homo s...  1943   0.0  
gi|169881252 general transcription factor II, i isoform 4 [Homo ...  1902   0.0  
gi|14670354 general transcription factor II, i isoform 3 [Homo s...  1890   0.0  
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]           472   e-133
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]          472   e-133
gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapi...   383   e-106
gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sap...   377   e-104
gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo ...   159   2e-38
gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]          131   3e-30
gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]          131   3e-30
gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]          131   3e-30
gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sap...   129   1e-29
gi|239752592 PREDICTED: hypothetical protein XP_002348308, parti...   129   2e-29
gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo ...   113   8e-25
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]     46   2e-04
gi|110349719 titin isoform N2-A [Homo sapiens]                         44   7e-04
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]          36   0.15 
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]           36   0.15 
gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]           36   0.15 
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    36   0.15 
gi|55741677 SET domain containing 1A [Homo sapiens]                    36   0.20 
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    35   0.45 
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          35   0.45 
gi|4557719 DNA ligase I [Homo sapiens]                                 34   0.59 
gi|190684675 X-ray repair cross complementing protein 1 [Homo sa...    34   0.77 
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]     34   0.77 
gi|239757124 PREDICTED: hypothetical protein [Homo sapiens]            33   1.00 
gi|113428448 PREDICTED: hypothetical protein [Homo sapiens]            33   1.00 
gi|169213522 PREDICTED: hypothetical protein [Homo sapiens]            33   1.00 

>gi|14670352 general transcription factor II, i isoform 2 [Homo
           sapiens]
          Length = 978

 Score = 1955 bits (5065), Expect = 0.0
 Identities = 978/978 (100%), Positives = 978/978 (100%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP 300
           EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP
Sbjct: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP 300

Query: 301 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 360
           PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK
Sbjct: 301 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 360

Query: 361 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 420
           GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN
Sbjct: 361 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 420

Query: 421 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 480
           STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN
Sbjct: 421 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 480

Query: 481 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 540
           DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV
Sbjct: 481 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 540

Query: 541 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 600
           KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS
Sbjct: 541 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 600

Query: 601 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 660
           PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK
Sbjct: 601 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 660

Query: 661 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 720
           VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL
Sbjct: 661 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 720

Query: 721 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 780
           FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK
Sbjct: 721 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 780

Query: 781 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 840
           IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS
Sbjct: 781 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 840

Query: 841 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 900
           KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY
Sbjct: 841 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 900

Query: 901 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 960
           LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE
Sbjct: 901 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 960

Query: 961 IKETDGSSQIKQEPDPTW 978
           IKETDGSSQIKQEPDPTW
Sbjct: 961 IKETDGSSQIKQEPDPTW 978


>gi|14670350 general transcription factor II, i isoform 1 [Homo
           sapiens]
          Length = 998

 Score = 1943 bits (5034), Expect = 0.0
 Identities = 978/998 (97%), Positives = 978/998 (97%), Gaps = 20/998 (2%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPAEDSTQHVP 280
           EESEDPDYYQYNIQ                    GSHHSSEGNEGTEMEVPAEDSTQHVP
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300

Query: 281 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 340
           SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
Sbjct: 301 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 360

Query: 341 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 400
           LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
Sbjct: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420

Query: 401 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 460
           RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
Sbjct: 421 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 480

Query: 461 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 520
           ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
Sbjct: 481 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 540

Query: 521 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 580
           PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
Sbjct: 541 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 600

Query: 581 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 640
           ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
Sbjct: 601 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 660

Query: 641 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 700
           INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
Sbjct: 661 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 720

Query: 701 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 760
           FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
Sbjct: 721 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 780

Query: 761 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 820
           RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
Sbjct: 781 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 840

Query: 821 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 880
           VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
Sbjct: 841 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 900

Query: 881 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 940
           PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
Sbjct: 901 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 960

Query: 941 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 978
           GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 961 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 998


>gi|169881252 general transcription factor II, i isoform 4 [Homo
           sapiens]
          Length = 957

 Score = 1902 bits (4926), Expect = 0.0
 Identities = 957/978 (97%), Positives = 957/978 (97%), Gaps = 21/978 (2%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP 300
           EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPA                     EDDDYSP
Sbjct: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPA---------------------EDDDYSP 279

Query: 301 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 360
           PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK
Sbjct: 280 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 339

Query: 361 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 420
           GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN
Sbjct: 340 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 399

Query: 421 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 480
           STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN
Sbjct: 400 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 459

Query: 481 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 540
           DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV
Sbjct: 460 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 519

Query: 541 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 600
           KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS
Sbjct: 520 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 579

Query: 601 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 660
           PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK
Sbjct: 580 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 639

Query: 661 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 720
           VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL
Sbjct: 640 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 699

Query: 721 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 780
           FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK
Sbjct: 700 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 759

Query: 781 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 840
           IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS
Sbjct: 760 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 819

Query: 841 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 900
           KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY
Sbjct: 820 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 879

Query: 901 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 960
           LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE
Sbjct: 880 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 939

Query: 961 IKETDGSSQIKQEPDPTW 978
           IKETDGSSQIKQEPDPTW
Sbjct: 940 IKETDGSSQIKQEPDPTW 957


>gi|14670354 general transcription factor II, i isoform 3 [Homo
           sapiens]
          Length = 977

 Score = 1890 bits (4895), Expect = 0.0
 Identities = 957/998 (95%), Positives = 957/998 (95%), Gaps = 41/998 (4%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPAEDSTQHVP 280
           EESEDPDYYQYNIQ                    GSHHSSEGNEGTEMEVPA        
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPA-------- 292

Query: 281 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 340
                        EDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
Sbjct: 293 -------------EDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 339

Query: 341 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 400
           LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
Sbjct: 340 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 399

Query: 401 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 460
           RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
Sbjct: 400 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 459

Query: 461 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 520
           ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
Sbjct: 460 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 519

Query: 521 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 580
           PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
Sbjct: 520 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 579

Query: 581 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 640
           ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
Sbjct: 580 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 639

Query: 641 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 700
           INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
Sbjct: 640 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 699

Query: 701 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 760
           FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
Sbjct: 700 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 759

Query: 761 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 820
           RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
Sbjct: 760 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 819

Query: 821 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 880
           VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
Sbjct: 820 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 879

Query: 881 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 940
           PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
Sbjct: 880 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 939

Query: 941 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 978
           GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 940 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 977


>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
          Length = 949

 Score =  472 bits (1215), Expect = e-133
 Identities = 265/448 (59%), Positives = 313/448 (69%), Gaps = 25/448 (5%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235

Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPS-ETSEDPEVEVTIEDDDYS 299
           +ESEDP+YYQYN+QGSH SS  NE  EME+P EDST  VPS E +EDPE EV IE +  S
Sbjct: 236 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNS 295

Query: 300 PPSKRPKAN----ELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQ 355
                  A      + Q  VP+       K R  + EK    I  LR+QV +LF RK+ +
Sbjct: 296 SSVTNSAAGVEDLNIVQVTVPD-----NEKERLSSIEK----IKQLREQVNDLFSRKFGE 346

Query: 356 AIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKK 415
           AI    PV +PY     +   + ++G+P G+ F+ P    I  + RIL A E I+F + +
Sbjct: 347 AIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406

Query: 416 H----ELLNSTREDLQLDKPASGVKEEW 439
                EL N  +   ++D+     +E+W
Sbjct: 407 PLPGLELSNVGKR--KIDQEGRVFQEKW 432



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 810 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 869
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353

Query: 870 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 929
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413

Query: 930 NNQLVDQSESEGPVIQESAE 949
           +N    + + EG V QE  E
Sbjct: 414 SNVGKRKIDQEGRVFQEKWE 433



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 341 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 400
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 401 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 455
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 456 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 502
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283

Query: 503 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 561
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342

Query: 562 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 621
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402

Query: 622 VVKKP 626
            V +P
Sbjct: 403 TVIRP 407



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 80/308 (25%), Positives = 127/308 (41%), Gaps = 77/308 (25%)

Query: 551 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 610
           LRK VE+ F   + +ALG T  V VPY     +   + V+GLPEG+ F+ P  + +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 611 RIVRGSNKIKFVVKKPEL------------------VISYLPPGMASKINTK-------- 644
            I+     I F++ +P L                  ++S  P      IN K        
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVS--PSESCGPINVKTEPMEDSG 224

Query: 645 ------ALQSPKRPRSP-------------GSNSKVPEIEVTVEGPN--------NNNPQ 677
                 A+   K    P              ++++V E+E+ +E           N +P+
Sbjct: 225 ISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPE 284

Query: 678 TSAVRTPTQTNGSN-----------------VPFKPRGREFSFEAWNAKITDLKQKVENL 720
            + V+    TN S+                 VP   + R  S E    KI  L+++V +L
Sbjct: 285 -AEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVNDL 339

Query: 721 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 780
           F+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL     
Sbjct: 340 FSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEF 399

Query: 781 IKFIIKKP 788
           IKF + +P
Sbjct: 400 IKFTVIRP 407



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 848 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 907
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 908 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 954
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 955 VPATEEIKETDGSSQIKQEPDPTW 978
           + A       +  S  K+  DP +
Sbjct: 227 LKA-------EAVSVKKESEDPNY 243


>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
          Length = 949

 Score =  472 bits (1215), Expect = e-133
 Identities = 265/448 (59%), Positives = 313/448 (69%), Gaps = 25/448 (5%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235

Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPS-ETSEDPEVEVTIEDDDYS 299
           +ESEDP+YYQYN+QGSH SS  NE  EME+P EDST  VPS E +EDPE EV IE +  S
Sbjct: 236 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNS 295

Query: 300 PPSKRPKAN----ELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQ 355
                  A      + Q  VP+       K R  + EK    I  LR+QV +LF RK+ +
Sbjct: 296 SSVTNSAAGVEDLNIVQVTVPD-----NEKERLSSIEK----IKQLREQVNDLFSRKFGE 346

Query: 356 AIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKK 415
           AI    PV +PY     +   + ++G+P G+ F+ P    I  + RIL A E I+F + +
Sbjct: 347 AIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406

Query: 416 H----ELLNSTREDLQLDKPASGVKEEW 439
                EL N  +   ++D+     +E+W
Sbjct: 407 PLPGLELSNVGKR--KIDQEGRVFQEKW 432



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 810 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 869
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353

Query: 870 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 929
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413

Query: 930 NNQLVDQSESEGPVIQESAE 949
           +N    + + EG V QE  E
Sbjct: 414 SNVGKRKIDQEGRVFQEKWE 433



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 341 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 400
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 401 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 455
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 456 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 502
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283

Query: 503 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 561
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342

Query: 562 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 621
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402

Query: 622 VVKKP 626
            V +P
Sbjct: 403 TVIRP 407



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 80/308 (25%), Positives = 127/308 (41%), Gaps = 77/308 (25%)

Query: 551 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 610
           LRK VE+ F   + +ALG T  V VPY     +   + V+GLPEG+ F+ P  + +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 611 RIVRGSNKIKFVVKKPEL------------------VISYLPPGMASKINTK-------- 644
            I+     I F++ +P L                  ++S  P      IN K        
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVS--PSESCGPINVKTEPMEDSG 224

Query: 645 ------ALQSPKRPRSP-------------GSNSKVPEIEVTVEGPN--------NNNPQ 677
                 A+   K    P              ++++V E+E+ +E           N +P+
Sbjct: 225 ISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPE 284

Query: 678 TSAVRTPTQTNGSN-----------------VPFKPRGREFSFEAWNAKITDLKQKVENL 720
            + V+    TN S+                 VP   + R  S E    KI  L+++V +L
Sbjct: 285 -AEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVNDL 339

Query: 721 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 780
           F+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL     
Sbjct: 340 FSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEF 399

Query: 781 IKFIIKKP 788
           IKF + +P
Sbjct: 400 IKFTVIRP 407



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 848 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 907
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 908 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 954
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 955 VPATEEIKETDGSSQIKQEPDPTW 978
           + A       +  S  K+  DP +
Sbjct: 227 LKA-------EAVSVKKESEDPNY 243


>gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 959

 Score =  383 bits (983), Expect = e-106
 Identities = 305/980 (31%), Positives = 472/980 (48%), Gaps = 170/980 (17%)

Query: 22  VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
           ++T L+SAL+SMC  L+K  AEVAC+AV++   FVVGTE+GR F+N RK+ Q DF+++C 
Sbjct: 30  IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89

Query: 82  EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
               K  E    K   +         R S++   ++  LRK VE+ F   Y +ALG+++V
Sbjct: 90  GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149

Query: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
           VP+PYE++LR+   + VQGLPEG+AF+ P  YD   L  ILE+   I F +KRP  +   
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206

Query: 194 HVGGR--VMVTDADRSILSPGGS--CG----PIKVKTEPTEDSGISLEMAAVTVKEESED 245
             GGR    + + +   L P GS  CG      KV  +    +  S  MA+         
Sbjct: 207 --GGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMAS--------- 255

Query: 246 PDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSE---TSEDPEVEVTIEDDDYSPPS 302
              + Y+    +H+       + E P   S    PS+   +   PE + T   D      
Sbjct: 256 ---FLYSTALPNHAI---RELKQEAP---SCPLAPSDLGLSRPMPEPKATGAQDFSDCCG 306

Query: 303 KRPKANELPQPPVPEPANAGKR---KVREFNFEKWNARITD------LRKQVEELFERKY 353
           ++P     P  P+ +  +A KR    +     EKW+A I +      LR+ V+ LF  +Y
Sbjct: 307 QKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRY 363

Query: 354 AQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVI 413
           A+A+     V +PY       E + + G+P+ IPF+RP TYG+P+L+RIL  +  I F+I
Sbjct: 364 AEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFII 423

Query: 414 KK--HELL---NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLFCK-KFAEALG-S 464
           K+   E +   N   +D    +PAS  ++     +R T L    +    K   +E  G  
Sbjct: 424 KRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPG 483

Query: 465 TEAKAVPYQKFEAHPNDLYV------------EGLPENIPFRSP---SWYGIPRLEKIIQ 509
           T  +    +  +  P DL +            E + +++P   P   S YG+        
Sbjct: 484 TSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGM-------- 535

Query: 510 VGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGL 569
                       E+LT             PV++     I  LRKQVE +FN ++A+A+G+
Sbjct: 536 ------------EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGI 583

Query: 570 TEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELV 629
           +E VKVPY  F  +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+PEL+
Sbjct: 584 SEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELL 643

Query: 630 ISYL-PPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTN 688
              +  P M S+    +L        P  +S  P ++ ++                    
Sbjct: 644 TEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESL-------------------- 683

Query: 689 GSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESF 745
                 K +G + +++A  ++I     L+++V++LFN+K GEALG+K  V+VP+   +S 
Sbjct: 684 ------KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSN 737

Query: 746 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPP 805
           P    +EGLP G+PFR+P TFG   LE+IL    KIKF + +P                 
Sbjct: 738 PGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP----------------- 780

Query: 806 RKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIG 865
                                 Q  IP  D +  +++ +   LREQV +LF+ K+GEA+G
Sbjct: 781 ---------------------FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALG 819

Query: 866 MGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI---R 922
           +  PV VPY+ I  +P  V V G+P  + F+ P+  +I  + +IL + E ++  +I   +
Sbjct: 820 LNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQ 879

Query: 923 PFPGLVINNQLVDQSESEGP 942
           PF   + N+  V   +S  P
Sbjct: 880 PF-AEICNDAKVPAKDSSIP 898



 Score =  260 bits (665), Expect = 4e-69
 Identities = 201/620 (32%), Positives = 289/620 (46%), Gaps = 84/620 (13%)

Query: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
           +I TLR+ V+  F   Y +ALG   +VPVPY K+  D  AV + G+P+ + FK P  Y +
Sbjct: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406

Query: 168 ATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTED 227
             LK ILE +  I FIIKR F E  +   G     D  +  L P            P ED
Sbjct: 407 PKLKRILEERHSIHFIIKRMFDE--RIFTGNKFTKDTTK--LEPAS----------PPED 452

Query: 228 SGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDP 287
           +   +  A V     +   D    + +     + G  G    +  E     +   T  DP
Sbjct: 453 TSAEVSRATVLDLAGNARSDKGSMS-EDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDP 511

Query: 288 EVEVTIEDDDYSPPSKRPKANE------LPQPPVPEPANAGKRKVREFNFEKWNARITDL 341
               T E+   S P   P  +       L    + E A   +R V + + +     I  L
Sbjct: 512 SP--TSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDV----IRPL 565

Query: 342 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 401
           RKQVE LF  +YA+AI    PV +PY  F  H E+L+V GLPEGI  RRP+ +GI +L +
Sbjct: 566 RKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRK 625

Query: 402 ILLAKERIRFVIKKHELL-----------NSTREDLQLDKPA------------------ 432
           IL A   I+FVIK+ ELL             T   L    PA                  
Sbjct: 626 ILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESLKR 685

Query: 433 SGVKEEWYARITK------LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEG 486
            G +E + AR+++      LR+ V  LF KK+ EALG      VPY++ +++P  + +EG
Sbjct: 686 QGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEG 745

Query: 487 LPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNV 546
           LP  IPFR P  +G   LE+I+ V ++IKF + RP           Q     P ++D N 
Sbjct: 746 LPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANR 795

Query: 547 RITK--LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWF 604
              K  LR+QV+E+FN K+ +ALGL   V VPY +   +P+ + V GLP+ IPFR+P  +
Sbjct: 796 LGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTY 855

Query: 605 GIPRLERIVRGSNKIKFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSK 660
            I RLE+I++    ++ V      +I+ L P       +K+  K    PKR R   S   
Sbjct: 856 DIHRLEKILKAREHVRMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGN 909

Query: 661 VPEIEVTVEGPNNNNPQTSA 680
                 +    +++NP + A
Sbjct: 910 SVSSSSSSSSSSSSNPDSVA 929



 Score =  143 bits (360), Expect = 9e-34
 Identities = 118/426 (27%), Positives = 192/426 (45%), Gaps = 120/426 (28%)

Query: 443 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 502
           I  LRK V+ LF  ++A+A+G +E   VPY KF  HP +L+V GLPE I  R P+ +GI 
Sbjct: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621

Query: 503 RLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTP----------------------- 539
           +L KI++  N I+FVIKRPELLT    E       T                        
Sbjct: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDE 681

Query: 540 ------VKEDWNVRITK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFL 587
                  +E+++ R+++      LR+QV+++FN K+       EA+ + Y          
Sbjct: 682 SLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYG------EALGIKY---------- 725

Query: 588 YVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQ 647
                P  +P++           RI      +         +I  LPPG+  +       
Sbjct: 726 -----PVQVPYK-----------RIKSNPGSV---------IIEGLPPGIPFR------- 753

Query: 648 SPKRPRSPGSNSK------VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 701
              +P + GS +         +I+ TV       P    +  P + + + +  K      
Sbjct: 754 ---KPCTFGSQNLERILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK------ 799

Query: 702 SFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFR 761
                      L+++V+ LFNEK GEALGL + V VP+ L    P+   V GLP+ +PFR
Sbjct: 800 ---------VILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFR 850

Query: 762 RPSTFGIPRLEKILRNKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPN 813
            P+T+ I RLEKIL+ +  ++  II + + F       +   K+S+  K   ++++   +
Sbjct: 851 NPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNS 910

Query: 814 VNTTAS 819
           V++++S
Sbjct: 911 VSSSSS 916



 Score =  102 bits (255), Expect = 1e-21
 Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)

Query: 551 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 610
           LRK VEE+F++ +++ALG    V +PY      P  L V+GLPEG+ FR P  +    L 
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187

Query: 611 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 670
            I+  S++I+F +K+P L           ++N  +L  PK  R  G + + P++      
Sbjct: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239

Query: 671 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 730
           P  + P       PT T+ S   F      +S    N  I +LKQ+  +         LG
Sbjct: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285

Query: 731 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 789
           L + +  P A   +  +DF           ++P+  G P ++ +  +K  +  I+  K E
Sbjct: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336

Query: 790 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 849
            ++  IKE+                       ED+N                      LR
Sbjct: 337 KWDAFIKET-----------------------EDINT---------------------LR 352

Query: 850 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 909
           E V  LF+ ++ EA+G+   V VPYRKI  +P  V + G+P  + FK P    +  ++RI
Sbjct: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412

Query: 910 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 955
           L+    I F + R F   +       +     E   P    SAE S+  V
Sbjct: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462


>gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 944

 Score =  377 bits (968), Expect = e-104
 Identities = 302/979 (30%), Positives = 469/979 (47%), Gaps = 183/979 (18%)

Query: 22  VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
           ++T L+SAL+SMC  L+K  AEVAC+AV++   FVVGTE+GR F+N RK+ Q DF+++C 
Sbjct: 30  IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89

Query: 82  EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
               K  E    K   +         R S++   ++  LRK VE+ F   Y +ALG+++V
Sbjct: 90  GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149

Query: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
           VP+PYE++LR+   + VQGLPEG+AF+ P  YD   L  ILE+   I F +KRP  +   
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206

Query: 194 HVGGR--VMVTDADRSILSPGGS--CG----PIKVKTEPTEDSGISLEMAAVTVKEESED 245
             GGR    + + +   L P GS  CG      KV  +    +  S  MA+         
Sbjct: 207 --GGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMAS--------- 255

Query: 246 PDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSE---TSEDPEVEVTIEDDDYSPPS 302
              + Y+    +H+       + E P   S    PS+   +   PE + T   D      
Sbjct: 256 ---FLYSTALPNHAI---RELKQEAP---SCPLAPSDLGLSRPMPEPKATGAQDFSDCCG 306

Query: 303 KRPKANELPQPPVPEPANAGKR---KVREFNFEKWNARITD------LRKQVEELFERKY 353
           ++P     P  P+ +  +A KR    +     EKW+A I +      LR+ V+ LF  +Y
Sbjct: 307 QKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRY 363

Query: 354 AQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVI 413
           A+A+     V +PY       E + + G+P+ IPF+RP TYG+P+L+RIL  +  I F+I
Sbjct: 364 AEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFII 423

Query: 414 KK--HELL---NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLFCK-KFAEALG-S 464
           K+   E +   N   +D    +PAS  ++     +R T L    +    K   +E  G  
Sbjct: 424 KRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPG 483

Query: 465 TEAKAVPYQKFEAHPNDLYV------------EGLPENIPFRSP---SWYGIPRLEKIIQ 509
           T  +    +  +  P DL +            E + +++P   P   S YG+        
Sbjct: 484 TSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGM-------- 535

Query: 510 VGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGL 569
                       E+LT             PV++     I  LRKQVE +FN ++A+A+G+
Sbjct: 536 ------------EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGI 583

Query: 570 TEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELV 629
           +E VKVPY  F  +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+PEL 
Sbjct: 584 SEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPEL- 642

Query: 630 ISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNG 689
                  +   +    + S +R      +S  P ++ ++                     
Sbjct: 643 -------LTEGVKEPIVDSQER------DSGDPLVDESL--------------------- 668

Query: 690 SNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFP 746
                K +G + +++A  ++I     L+++V++LFN+K GEALG+K  V+VP+   +S P
Sbjct: 669 -----KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNP 723

Query: 747 EDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPR 806
               +EGLP G+PFR+P TFG   LE+IL    KIKF + +P                  
Sbjct: 724 GSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP------------------ 765

Query: 807 KINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGM 866
                                Q  IP  D +  +++ +   LREQV +LF+ K+GEA+G+
Sbjct: 766 --------------------FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGL 805

Query: 867 GFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI---RP 923
             PV VPY+ I  +P  V V G+P  + F+ P+  +I  + +IL + E ++  +I   +P
Sbjct: 806 NRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQP 865

Query: 924 FPGLVINNQLVDQSESEGP 942
           F   + N+  V   +S  P
Sbjct: 866 F-AEICNDAKVPAKDSSIP 883



 Score =  263 bits (672), Expect = 6e-70
 Identities = 198/605 (32%), Positives = 289/605 (47%), Gaps = 69/605 (11%)

Query: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
           +I TLR+ V+  F   Y +ALG   +VPVPY K+  D  AV + G+P+ + FK P  Y +
Sbjct: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406

Query: 168 ATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTED 227
             LK ILE +  I FIIKR F E  +   G     D  +  L P            P ED
Sbjct: 407 PKLKRILEERHSIHFIIKRMFDE--RIFTGNKFTKDTTK--LEPAS----------PPED 452

Query: 228 SGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDP 287
           +   +  A V     +   D    + +     + G  G    +  E     +   T  DP
Sbjct: 453 TSAEVSRATVLDLAGNARSDKGSMS-EDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDP 511

Query: 288 EVEVTIEDDDYSPPSKRPKANE------LPQPPVPEPANAGKRKVREFNFEKWNARITDL 341
               T E+   S P   P  +       L    + E A   +R V + + +     I  L
Sbjct: 512 SP--TSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDV----IRPL 565

Query: 342 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 401
           RKQVE LF  +YA+AI    PV +PY  F  H E+L+V GLPEGI  RRP+ +GI +L +
Sbjct: 566 RKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRK 625

Query: 402 ILLAKERIRFVIKKHELLNSTREDLQLDK--------------PASGVKEEWYARITK-- 445
           IL A   I+FVIK+ ELL    ++  +D                  G +E + AR+++  
Sbjct: 626 ILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSRID 685

Query: 446 ----LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGI 501
               LR+ V  LF KK+ EALG      VPY++ +++P  + +EGLP  IPFR P  +G 
Sbjct: 686 IANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGS 745

Query: 502 PRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITK--LRKQVEEIF 559
             LE+I+ V ++IKF + RP           Q     P ++D N    K  LR+QV+E+F
Sbjct: 746 QNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANRLGEKVILREQVKELF 795

Query: 560 NLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKI 619
           N K+ +ALGL   V VPY +   +P+ + V GLP+ IPFR+P  + I RLE+I++    +
Sbjct: 796 NEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHV 855

Query: 620 KFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNN 675
           + V      +I+ L P       +K+  K    PKR R   S         +    +++N
Sbjct: 856 RMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSN 909

Query: 676 PQTSA 680
           P + A
Sbjct: 910 PDSVA 914



 Score =  149 bits (375), Expect = 2e-35
 Identities = 118/411 (28%), Positives = 193/411 (46%), Gaps = 105/411 (25%)

Query: 443 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 502
           I  LRK V+ LF  ++A+A+G +E   VPY KF  HP +L+V GLPE I  R P+ +GI 
Sbjct: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621

Query: 503 RLEKIIQVGNRIKFVIKRPELLTHSTTE--------------VTQPRTNTPVKEDWNVRI 548
           +L KI++  N I+FVIKRPELLT    E              V +       +E+++ R+
Sbjct: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681

Query: 549 TK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPT 602
           ++      LR+QV+++FN K+       EA+ + Y               P  +P++   
Sbjct: 682 SRIDIANTLREQVQDLFNKKYG------EALGIKY---------------PVQVPYK--- 717

Query: 603 WFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK-- 660
                   RI      +         +I  LPPG+  +          +P + GS +   
Sbjct: 718 --------RIKSNPGSV---------IIEGLPPGIPFR----------KPCTFGSQNLER 750

Query: 661 ----VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQK 716
                 +I+ TV       P    +  P + + + +  K                 L+++
Sbjct: 751 ILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK---------------VILREQ 790

Query: 717 VENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILR 776
           V+ LFNEK GEALGL + V VP+ L    P+   V GLP+ +PFR P+T+ I RLEKIL+
Sbjct: 791 VKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILK 850

Query: 777 NKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPNVNTTAS 819
            +  ++  II + + F       +   K+S+  K   ++++   +V++++S
Sbjct: 851 AREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSS 901



 Score =  102 bits (255), Expect = 1e-21
 Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)

Query: 551 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 610
           LRK VEE+F++ +++ALG    V +PY      P  L V+GLPEG+ FR P  +    L 
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187

Query: 611 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 670
            I+  S++I+F +K+P L           ++N  +L  PK  R  G + + P++      
Sbjct: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239

Query: 671 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 730
           P  + P       PT T+ S   F      +S    N  I +LKQ+  +         LG
Sbjct: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285

Query: 731 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 789
           L + +  P A   +  +DF           ++P+  G P ++ +  +K  +  I+  K E
Sbjct: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336

Query: 790 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 849
            ++  IKE+                       ED+N                      LR
Sbjct: 337 KWDAFIKET-----------------------EDINT---------------------LR 352

Query: 850 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 909
           E V  LF+ ++ EA+G+   V VPYRKI  +P  V + G+P  + FK P    +  ++RI
Sbjct: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412

Query: 910 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 955
           L+    I F + R F   +       +     E   P    SAE S+  V
Sbjct: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462


>gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo
           sapiens]
          Length = 145

 Score =  159 bits (401), Expect = 2e-38
 Identities = 98/187 (52%), Positives = 111/187 (59%), Gaps = 43/187 (22%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESM-CKELAKSKAEVACIAVYETDVFVVGT 59
           MAQV +STL +EDE+S ESRMVVTFLMSALES  C  +   K E  C  +Y   V+  G 
Sbjct: 1   MAQVLVSTLSIEDEDSYESRMVVTFLMSALESTDCFRVWILKQE--CTLIYHKKVYNPG- 57

Query: 60  ERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDY 119
                                        E  + +     N          T +KTVEDY
Sbjct: 58  -----------------------------ESDECRCCRNGN----------TRKKTVEDY 78

Query: 120 FCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAG 179
           FCFC  KAL K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL+WILE  AG
Sbjct: 79  FCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAG 138

Query: 180 ISFIIKR 186
           ISFIIKR
Sbjct: 139 ISFIIKR 145



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 39/74 (52%)

Query: 447 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 506
           +K V+  FC    +AL       VPY+K     + L V+GLPE + F+ P  Y +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 507 IIQVGNRIKFVIKR 520
           I++    I F+IKR
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 29/74 (39%), Positives = 38/74 (51%)

Query: 714 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 773
           K+ VE+ F   C +AL     V VP+           V+GLPEGV F+ P  + +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 774 ILRNKAKIKFIIKK 787
           IL   A I FIIK+
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 26/74 (35%), Positives = 38/74 (51%)

Query: 342 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 401
           +K VE+ F     +A++    V +PY         L V+GLPEG+ F+ P  Y +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 402 ILLAKERIRFVIKK 415
           IL     I F+IK+
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/74 (33%), Positives = 39/74 (52%)

Query: 552 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 611
           +K VE+ F     +AL     V VPY     +   L V+GLPEG+ F+ P  + +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 612 IVRGSNKIKFVVKK 625
           I+  +  I F++K+
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 22/74 (29%), Positives = 39/74 (52%)

Query: 849 REQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRR 908
           ++ V D F     +A+     V VPY K+  +   ++V G+P GV+FK P   +++++  
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 909 ILDSAEFIKFTVIR 922
           IL+    I F + R
Sbjct: 132 ILEYTAGISFIIKR 145


>gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 298

 Score =  131 bits (330), Expect = 3e-30
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 746 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 797
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62

Query: 798 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 856
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118

Query: 857 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 916
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176

Query: 917 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 949
            FTV RPF GL+      D +     ++QE  +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209



 Score =  111 bits (278), Expect = 3e-24
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 478 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 530
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 531 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 562
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 563 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 622
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 623 VKKP 626
           V +P
Sbjct: 180 VTRP 183



 Score =  107 bits (268), Expect = 4e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 373 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 421
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 422 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 457
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 458 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 517
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 518 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 571
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224



 Score =  101 bits (251), Expect = 4e-21
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 583 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 641
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 642 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 701
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95

Query: 702 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 758
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155

Query: 759 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 818
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191

Query: 819 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 864
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 298 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 354
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123

Query: 355 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 414
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181

Query: 415 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 462
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166

Query: 171 KWILENKAGISFIIKRPF 188
           + IL     I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47



 Score = 33.5 bits (75), Expect = 1.00
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 879 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 923
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score =  131 bits (330), Expect = 3e-30
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 746 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 797
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62

Query: 798 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 856
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118

Query: 857 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 916
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176

Query: 917 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 949
            FTV RPF GL+      D +     ++QE  +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209



 Score =  111 bits (278), Expect = 3e-24
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 478 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 530
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 531 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 562
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 563 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 622
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 623 VKKP 626
           V +P
Sbjct: 180 VTRP 183



 Score =  107 bits (268), Expect = 4e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 373 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 421
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 422 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 457
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 458 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 517
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 518 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 571
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224



 Score =  101 bits (251), Expect = 4e-21
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 583 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 641
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 642 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 701
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95

Query: 702 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 758
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155

Query: 759 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 818
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191

Query: 819 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 864
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 298 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 354
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123

Query: 355 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 414
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181

Query: 415 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 462
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166

Query: 171 KWILENKAGISFIIKRPF 188
           + IL     I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47



 Score = 33.5 bits (75), Expect = 1.00
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 879 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 923
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score =  131 bits (330), Expect = 3e-30
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 746 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 797
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62

Query: 798 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 856
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118

Query: 857 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 916
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176

Query: 917 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 949
            FTV RPF GL+      D +     ++QE  +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209



 Score =  111 bits (278), Expect = 3e-24
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 478 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 530
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 531 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 562
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 563 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 622
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 623 VKKP 626
           V +P
Sbjct: 180 VTRP 183



 Score =  107 bits (268), Expect = 4e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 373 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 421
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 422 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 457
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 458 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 517
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 518 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 571
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224



 Score =  101 bits (251), Expect = 4e-21
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 583 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 641
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 642 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 701
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95

Query: 702 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 758
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155

Query: 759 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 818
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191

Query: 819 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 864
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 298 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 354
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123

Query: 355 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 414
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181

Query: 415 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 462
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166

Query: 171 KWILENKAGISFIIKRPF 188
           + IL     I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47



 Score = 33.5 bits (75), Expect = 1.00
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 879 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 923
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo
           sapiens]
          Length = 304

 Score =  129 bits (324), Expect = 1e-29
 Identities = 62/75 (82%), Positives = 67/75 (89%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           T +KTVEDYFCFC  KAL K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL
Sbjct: 19  TRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATL 78

Query: 171 KWILENKAGISFIIK 185
           +WILE  AGISFIIK
Sbjct: 79  EWILEYTAGISFIIK 93



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 8/98 (8%)

Query: 714 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 773
           K+ VE+ F   C +AL     V VP+           V+GLPEGV F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 774 ILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSS 811
           IL   A I FIIK               ++PP ++N +
Sbjct: 81  ILEYTAGISFIIKS--------SGEPQGRTPPLRLNQA 110



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 26/73 (35%), Positives = 38/73 (52%)

Query: 447 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 506
           +K V+  FC    +AL       VPY+K     + L V+GLPE + F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 507 IIQVGNRIKFVIK 519
           I++    I F+IK
Sbjct: 81  ILEYTAGISFIIK 93



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 26/73 (35%), Positives = 37/73 (50%)

Query: 342 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 401
           +K VE+ F     +A++    V +PY         L V+GLPEG+ F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 402 ILLAKERIRFVIK 414
           IL     I F+IK
Sbjct: 81  ILEYTAGISFIIK 93



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 25/73 (34%), Positives = 38/73 (52%)

Query: 552 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 611
           +K VE+ F     +AL     V VPY     +   L V+GLPEG+ F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 612 IVRGSNKIKFVVK 624
           I+  +  I F++K
Sbjct: 81  ILEYTAGISFIIK 93



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 21/72 (29%), Positives = 38/72 (52%)

Query: 849 REQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRR 908
           ++ V D F     +A+     V VPY K+  +   ++V G+P GV+FK P   +++++  
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 909 ILDSAEFIKFTV 920
           IL+    I F +
Sbjct: 81  ILEYTAGISFII 92


>gi|239752592 PREDICTED: hypothetical protein XP_002348308, partial
           [Homo sapiens]
          Length = 94

 Score =  129 bits (323), Expect = 2e-29
 Identities = 62/76 (81%), Positives = 67/76 (88%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           T +KTVEDYFCFC  K L K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL
Sbjct: 19  TRKKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATL 78

Query: 171 KWILENKAGISFIIKR 186
           +WILE  AGISFIIKR
Sbjct: 79  EWILEYTAGISFIIKR 94



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 26/74 (35%), Positives = 38/74 (51%)

Query: 447 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 506
           +K V+  FC    + L       VPY+K     + L V+GLPE + F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 507 IIQVGNRIKFVIKR 520
           I++    I F+IKR
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 28/74 (37%), Positives = 37/74 (50%)

Query: 714 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 773
           K+ VE+ F   C + L     V VP+           V+GLPEGV F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 774 ILRNKAKIKFIIKK 787
           IL   A I FIIK+
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/74 (33%), Positives = 37/74 (50%)

Query: 342 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 401
           +K VE+ F     + ++    V +PY         L V+GLPEG+ F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 402 ILLAKERIRFVIKK 415
           IL     I F+IK+
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 24/74 (32%), Positives = 38/74 (51%)

Query: 552 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 611
           +K VE+ F     + L     V VPY     +   L V+GLPEG+ F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 612 IVRGSNKIKFVVKK 625
           I+  +  I F++K+
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 18/53 (33%), Positives = 31/53 (58%)

Query: 870 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIR 922
           V VPY K+  +   ++V G+P GV+FK P   +++++  IL+    I F + R
Sbjct: 42  VPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 94


>gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo
           sapiens]
          Length = 361

 Score =  113 bits (283), Expect = 8e-25
 Identities = 76/187 (40%), Positives = 94/187 (50%), Gaps = 40/187 (21%)

Query: 303 KRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGP 362
           ++ K NE PQPPVPEPANAG+RK+REFN EKWN RI DLRKQ EEL ERKY  +   K  
Sbjct: 214 RKTKTNEPPQPPVPEPANAGERKMREFNSEKWNHRIADLRKQTEELSERKYGMSKLEKSC 273

Query: 363 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNST 422
             +   ++   VE L++ G+P   P       G+P    IL            HEL+NST
Sbjct: 274 NLMFMGVYT--VELLFIMGVPWTSP-------GLPASHAILTC-------FSLHELMNST 317

Query: 423 REDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDL 482
            EDLQLDK          AR  K +  V                   +PY  F++H  D 
Sbjct: 318 GEDLQLDKSTLS------ARAVKAKGPV------------------MIPYPFFQSHVEDF 353

Query: 483 YVEGLPE 489
           Y E LP+
Sbjct: 354 YAEALPK 360



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 13/28 (46%), Positives = 18/28 (64%)

Query: 699 REFSFEAWNAKITDLKQKVENLFNEKCG 726
           REF+ E WN +I DL+++ E L   K G
Sbjct: 238 REFNSEKWNHRIADLRKQTEELSERKYG 265



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 13/29 (44%), Positives = 18/29 (62%)

Query: 728 ALGLKQAVKVPFALFESFPEDFYVEGLPE 756
           A+  K  V +P+  F+S  EDFY E LP+
Sbjct: 332 AVKAKGPVMIPYPFFQSHVEDFYAEALPK 360


>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo
          sapiens]
          Length = 561

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 29/41 (70%), Positives = 32/41 (78%), Gaps = 7/41 (17%)

Query: 1  MAQVAMSTLP------VEDEESSESRMVVTFLMSALESMCK 35
          MAQVA+STLP      VEDEES ESRMVVTFL SAL+SM +
Sbjct: 1  MAQVAVSTLPIEDEESVEDEESLESRMVVTFL-SALDSMVR 40


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 133/606 (21%), Positives = 221/606 (36%), Gaps = 124/606 (20%)

Query: 267   EMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKV 326
             E E+P E+  + VP E    PE E  + +++  P  K       P+ PVP P    K+KV
Sbjct: 10144 EEEIPPEE--EEVPPEEEYVPEEEEFVPEEEVLPEVK-------PKVPVPAPVPEIKKKV 10194

Query: 327   REFNF------EKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVE 380
              E         E   A++ ++ K+VEE       + I  K    +P  + +   E+   E
Sbjct: 10195 TEKKVVIPKKEEAPPAKVPEVPKKVEE------KRIILPKEEEVLPVEVTEEPEEEPISE 10248

Query: 381   GLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWY 440
                E IP   PS   I  +E +  A  R+  VIKK      T    +++ P + V     
Sbjct: 10249 ---EEIPEEPPS---IEEVEEV--APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVS---- 10296

Query: 441   ARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRS----- 495
                            KK  E     E   VP QK EA P    V  +P+ +P +      
Sbjct: 10297 ---------------KKIPE-----EKVPVPVQKKEAPP--AKVPEVPKKVPEKKVLVPK 10334

Query: 496   ----PSWYGIPRLEKIIQVGNRIKFVIKRP---ELLTHSTTEVTQPRTNTPVKEDWN--- 545
                 P   G   LE+ + V  R + V+K     E++     E+ +      V+E +    
Sbjct: 10335 KEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGE 10394

Query: 546   -------VRITKLR-------KQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEG 591
                    +++ + R       ++V  +  +  A+ + + E  K P    E + + +  + 
Sbjct: 10395 FHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKK 10454

Query: 592   LPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVK---KPELVISYLPPGMASKINTKALQS 648
              P  +  R      +P + + +    K++   +    P  V   LPP          +  
Sbjct: 10455 PPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPP 10514

Query: 649   PKRPRSP------GSNSKVPEIEVTV------EGPNNNNPQTSAVRTPTQTNGSNVPFKP 696
              K+P +P           VPE +V V      E P    P+      P +     +P KP
Sbjct: 10515 AKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKP 10574

Query: 697   RGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQ----AVKVPFALFESFPEDFYVE 752
                        +   ++ +  + +  EK   A   K+     VKVP A  E  PE   V 
Sbjct: 10575 ----------ESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK-KVP 10623

Query: 753   GLPEGVPFRRPSTFGIPRLEKILRNKAKIKFII------KKPEMFETAIKESTSSKSPPR 806
               P   P   P+   +P + K+   + K+   I        PE+FE    E  + + PP 
Sbjct: 10624 VPPPKKPEVPPTK--VPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE--PEEVALEEPPA 10679

Query: 807   KINSSP 812
             ++   P
Sbjct: 10680 EVVEEP 10685



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 91/425 (21%), Positives = 161/425 (37%), Gaps = 95/425 (22%)

Query: 269   EVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPE---PANAGKRK 325
             E P       VP +   + +V V +     +PP+K P   E+P+ PVPE   P  A K+ 
Sbjct: 9997  EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVP---EVPKKPVPEKKVPVPAPKK- 10052

Query: 326   VREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEG 385
                   E   A++ ++ K++            + K P  +P            VE  P  
Sbjct: 10053 -----VEAPPAKVPEVPKKL----------IPEEKKPTPVPKK----------VEAPPPK 10087

Query: 386   IPFRR---PSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYAR 442
             +P +R   P    +P+ E +L  +E    ++ + E+L    E L  ++     +EE    
Sbjct: 10088 VPKKREPVPVPVALPQEEEVLFEEE----IVPEEEVLPEEEEVLPEEEEVLPEEEEVL-- 10141

Query: 443   ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 502
                                    E + +P ++ E  P + YV   PE   F       +P
Sbjct: 10142 ----------------------PEEEEIPPEEEEVPPEEEYV---PEEEEF-------VP 10169

Query: 503   RLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDW-NVRITKLRKQVEEIFNL 561
               E + +V  ++      PE+      +VT+ +   P KE+    ++ ++ K+VEE    
Sbjct: 10170 EEEVLPEVKPKVPVPAPVPEI----KKKVTEKKVVIPKKEEAPPAKVPEVPKKVEE---- 10221

Query: 562   KFAQALGLTEAVKVPYPVFES-NPEFLYVEGLPEGIP-FRSPTWFGIPRLERIVRGSNKI 619
                + +   E   +P  V E    E +  E +PE  P          PR+  +++     
Sbjct: 10222 --KRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIK----- 10274

Query: 620   KFVVKKPELV---ISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNP 676
             K V + P  V   +   P  ++ KI  + +  P + +     +KVPE+   V       P
Sbjct: 10275 KAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQ-KKEAPPAKVPEVPKKVPEKKVLVP 10333

Query: 677   QTSAV 681
             +  AV
Sbjct: 10334 KKEAV 10338



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 56/221 (25%), Positives = 84/221 (38%), Gaps = 36/221 (16%)

Query: 134   VPVPYEKMLRDQSA-VVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPK 192
             V VP +K + ++ A  VV   PE    K PE       K ++  K       K P + PK
Sbjct: 10693 VTVPPKKPVPEKKAPAVVAKKPELPPVKVPE-----VPKEVVPEK-------KVPLVVPK 10740

Query: 193   KHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTE-----DSGISLEMAAVTVKEESEDPD 247
             K       V +  + ++       P K +  P +        +  E  AV V E +E P 
Sbjct: 10741 KPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPP 10800

Query: 248   YYQYNIQGSHHSSEGNEGTEMEVP---AEDSTQHVPSETSED------PEVEVTIEDDDY 298
                Y  +    + E     E E P   AE+    VP     +      PE +V +     
Sbjct: 10801 PEVYE-EPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPE 10859

Query: 299   SPPSKRPKANEL-------PQPPVPEPANAGKRKVREFNFE 332
             +PP K P+  ++       P+PP P PA   K  V+E  F+
Sbjct: 10860 APPPKEPEPEKVIEKPKLKPRPPPPPPA-PPKEDVKEKIFQ 10899



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 59/240 (24%), Positives = 91/240 (37%), Gaps = 31/240 (12%)

Query: 135  PVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKKH 194
            PVP EK+           +P  VA K P      + K ++E K  ++   K  F  P++ 
Sbjct: 9434 PVPEEKV----------AVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEE-KLSFAVPQRV 9482

Query: 195  VGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYY----Q 250
               R  V+  +    S       I V  E   +     E A VT  E  E+P+ Y    +
Sbjct: 9483 EVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEE---EEAEVTEYEVMEEPEEYVVEEK 9539

Query: 251  YNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP----PSKRPK 306
             +I      +E  E TE +         +P++  E P  +V        P    P+  PK
Sbjct: 9540 LHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPK 9599

Query: 307  ANELPQPPVPE------PANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 360
              ++P P VPE      P      KV +   E   A++T+   Q+ +  E K   A+  K
Sbjct: 9600 KEKVPPPKVPEEPKKPVPEKKVPPKVIKME-EPLPAKVTERHMQITQ--EEKVLVAVTKK 9656



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 40/131 (30%), Positives = 57/131 (43%), Gaps = 19/131 (14%)

Query: 200  MVTDADRSILSPGGSCGPIKVKTEPTE-DSGISLEMAAVTVK--EESEDPDYYQYNIQGS 256
            +V +   SI +P     PIK  T   E +   +LE  AV+V+  EE E+ + Y Y     
Sbjct: 9699 VVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDY----- 9753

Query: 257  HHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDY-SPPSKRPKANELPQPPV 315
                   E  E E P E+  Q+   E  E+ E E   E ++Y + P K      +P+ PV
Sbjct: 9754 ------KEFEEYE-PTEEYDQY---EEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPV 9803

Query: 316  PEPANAGKRKV 326
            P    A   KV
Sbjct: 9804 PTKPKAPPAKV 9814


>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
          Length = 490

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 29/124 (23%)

Query: 214 SCGPIKVKTEPTEDSGISLEMAA-----------VTVKEESEDPDYYQYNIQGSHHSSEG 262
           SCG   V  +P ED   S   ++           ++    S D D+Y++  +GS   SEG
Sbjct: 321 SCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSAD-DHYEFATKGSQEGSEG 379

Query: 263 NEGTEMEVPAEDSTQHVPSETSED------PEVEVTIEDDDYSPPSKR----PKANELPQ 312
           +EG+         +   PS+T ED       E + ++ D  Y+   K+     KA ++P 
Sbjct: 380 SEGS-------FRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVPS 432

Query: 313 PPVP 316
             +P
Sbjct: 433 DTLP 436


>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
          Length = 468

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 29/124 (23%)

Query: 214 SCGPIKVKTEPTEDSGISLEMAA-----------VTVKEESEDPDYYQYNIQGSHHSSEG 262
           SCG   V  +P ED   S   ++           ++    S D D+Y++  +GS   SEG
Sbjct: 299 SCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSAD-DHYEFATKGSQEGSEG 357

Query: 263 NEGTEMEVPAEDSTQHVPSETSED------PEVEVTIEDDDYSPPSKR----PKANELPQ 312
           +EG+         +   PS+T ED       E + ++ D  Y+   K+     KA ++P 
Sbjct: 358 SEGS-------FRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVPS 410

Query: 313 PPVP 316
             +P
Sbjct: 411 DTLP 414


>gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
          Length = 939

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 24/105 (22%), Positives = 51/105 (48%), Gaps = 7/105 (6%)

Query: 607 PRLERIVRGSNKIKFVVKKPELV------ISYLPPGMASKINTKALQS-PKRPRSPGSNS 659
           P  E+  + +NK KF +++PE++      + + P  +++   +   +S P+R  S G+NS
Sbjct: 460 PTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNS 519

Query: 660 KVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFE 704
               +    + P  + P++++++    T  S +  K R     FE
Sbjct: 520 YATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFE 564


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 9/65 (13%)

Query: 252 NIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETS--EDPEVEVTIEDDDYSPPSKRPKANE 309
           N + SHH+SEG + +      +DS+ H  SE+S   D E E +  D + + PS+   A+ 
Sbjct: 410 NSEPSHHNSEGADNSR-----DDSSSHSGSESSSGSDSESESSSSDSEANEPSQ--SASP 462

Query: 310 LPQPP 314
            P+PP
Sbjct: 463 EPEPP 467


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 35.8 bits (81), Expect = 0.20
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 11/83 (13%)

Query: 246 PDYYQ-YNIQGSHHSSEGNEGTEMEVP----AEDSTQHVP-SETSEDPEVEVTIEDDDYS 299
           P YY+ +N    H S      T  E P    AE++ +  P S TS  P       D DY 
Sbjct: 367 PAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYR 426

Query: 300 PPSKRPKANELPQPPVPEPANAG 322
           PP     A+E P P  PEP   G
Sbjct: 427 PP-----ASEAPPPEPPEPGGGG 444



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 8/71 (11%)

Query: 252 NIQGSHHSSEGNEGTEMEVP-AEDSTQHVPSETSEDPEVEVTIEDDDYS---PPSKRPKA 307
           N +    +  G  G   E P A    Q  P  + +D E    I DDD     PP+  P  
Sbjct: 547 NFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDME----ISDDDRGGSPPPAPTPPQ 602

Query: 308 NELPQPPVPEP 318
              P PP P P
Sbjct: 603 QPPPPPPPPPP 613


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 34.7 bits (78), Expect = 0.45
 Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 13/145 (8%)

Query: 223 EPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSE 282
           E T  S  S++   ++  E +E   +    +Q    S +  E  E E PA    Q   ++
Sbjct: 695 ERTSTSSSSVQARRLSQPESAEK--HVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQ 752

Query: 283 TSEDPEVEV---TIEDDD---YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNA 336
           TS  PE E    T+E+ +         RP+ N++P+PP+P           E + E    
Sbjct: 753 TSHLPESERIHHTVEEKEEVTMDTSENRPE-NDVPEPPMPIADQVSNDDRPEGSVEDEEK 811

Query: 337 RITDLRKQVEELFERKYAQAIKAKG 361
           + + L K     F+RK +     KG
Sbjct: 812 KESSLPKS----FKRKISVVSATKG 832


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 34.7 bits (78), Expect = 0.45
 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 5/103 (4%)

Query: 218  IKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTE--MEVPAEDS 275
            IKV  E  E + +S E+    V+E    P+     +     S  G+ G     + P ++ 
Sbjct: 1286 IKVSAE-AEVAPVSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEK 1344

Query: 276  TQHVPSETSE-DPEVEVTIEDDDYSPPSKRPKANELPQPPVPE 317
            + H+P+E  E  P V V+ E  D    ++R   + + + PVP+
Sbjct: 1345 SSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDE-PVPD 1386


>gi|4557719 DNA ligase I [Homo sapiens]
          Length = 919

 Score = 34.3 bits (77), Expect = 0.59
 Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 219 KVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQH 278
           +V  E +ED     +      +EE+      +  +       +G++ T    P + S   
Sbjct: 135 EVLEEQSEDEDREAKRKKEEEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAE 194

Query: 279 VPSETSEDPEV----EVTIEDDDYSPPSKRPK 306
            P+E+  +PEV    E+  E++   PP + PK
Sbjct: 195 TPTESVSEPEVATKQELQEEEEQTKPPRRAPK 226



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 5/71 (7%)

Query: 263 NEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPK-----ANELPQPPVPE 317
           +E  E +   E+  +  P E+  + EV    E +D   P+  PK       E P   V E
Sbjct: 143 DEDREAKRKKEEEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVSE 202

Query: 318 PANAGKRKVRE 328
           P  A K++++E
Sbjct: 203 PEVATKQELQE 213


>gi|190684675 X-ray repair cross complementing protein 1 [Homo
           sapiens]
          Length = 633

 Score = 33.9 bits (76), Expect = 0.77
 Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 15/111 (13%)

Query: 219 KVKTEPTEDSGISLEMAAVTVKEE-------SEDPDYYQYNIQGSHHSSEGNEGTEMEV- 270
           + KT+PT+ +G S      T +E         ED D      +G  + +E +  TE E+ 
Sbjct: 434 QTKTKPTQAAGPSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSGDTEDELR 493

Query: 271 -PAEDSTQHVP---SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPE 317
             AE     +P    E  EDP    T E+ D     + P   +LP P +P+
Sbjct: 494 RVAEQKEHRLPPGQEENGEDPYAGSTDENTDSEEHQEPP---DLPVPELPD 541


>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
          Length = 1388

 Score = 33.9 bits (76), Expect = 0.77
 Identities = 16/49 (32%), Positives = 24/49 (48%)

Query: 637 MASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPT 685
           M +K++ K L  P   + PG  S  P   +T  G   N+P +  + TPT
Sbjct: 710 MRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPT 758


>gi|239757124 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 106

 Score = 33.5 bits (75), Expect = 1.00
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 121 CFCYGKALGKSTVVPVPYE--KMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKA 178
           C  Y + L  S ++P   E  K  R ++    +G+   +  KH E  DL  L W++E   
Sbjct: 5   CLLYERFLRTSPLLPTCGEDNKEKRSRNQKASRGMRCRIPIKHSEGADLTVLVWVVERDI 64

Query: 179 GISFIIKRPFLEPKKH 194
            +   +  PF  P  H
Sbjct: 65  SV-LSVSTPFRIPLNH 79


>gi|113428448 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 90

 Score = 33.5 bits (75), Expect = 1.00
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 121 CFCYGKALGKSTVVPVPYE--KMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKA 178
           C  Y + L  S ++P   E  K  R ++    +G+   +  KH E  DL  L W++E   
Sbjct: 5   CLLYERFLRTSPLLPTCGEDNKEKRSRNQKASRGMRCRIPIKHSEGADLTVLVWVVERDI 64

Query: 179 GISFIIKRPFLEPKKH 194
            +   +  PF  P  H
Sbjct: 65  SV-LSVSTPFRIPLNH 79


>gi|169213522 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 106

 Score = 33.5 bits (75), Expect = 1.00
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 121 CFCYGKALGKSTVVPVPYE--KMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKA 178
           C  Y + L  S ++P   E  K  R ++    +G+   +  KH E  DL  L W++E   
Sbjct: 5   CLLYERFLRTSPLLPTCGEDNKEKRSRNQKASRGMRCRIPIKHSEGADLTVLVWVVERDI 64

Query: 179 GISFIIKRPFLEPKKH 194
            +   +  PF  P  H
Sbjct: 65  SV-LSVSTPFRIPLNH 79


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,500,831
Number of Sequences: 37866
Number of extensions: 1966429
Number of successful extensions: 6818
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 6351
Number of HSP's gapped (non-prelim): 345
length of query: 978
length of database: 18,247,518
effective HSP length: 112
effective length of query: 866
effective length of database: 14,006,526
effective search space: 12129651516
effective search space used: 12129651516
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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