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Search of human proteins with 144227752
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|144227752 GRAM domain containing 1B [Homo sapiens]
(738 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|144227752 GRAM domain containing 1B [Homo sapiens] 1503 0.0
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens] 634 0.0
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens] 602 e-172
gi|187936935 GRAM domain containing 1C [Homo sapiens] 466 e-131
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens] 100 6e-21
gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens] 100 6e-21
gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens] 100 6e-21
gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens] 99 1e-20
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens] 94 6e-19
gi|60593095 GRAM domain containing 2 [Homo sapiens] 92 2e-18
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 65 2e-10
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso... 60 6e-09
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 60 6e-09
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso... 56 1e-07
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso... 56 1e-07
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 46 1e-04
gi|125656165 THO complex 2 [Homo sapiens] 36 0.11
gi|46409326 C-type lectin domain family 9, member A [Homo sapiens] 36 0.15
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 36 0.15
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 36 0.15
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 36 0.15
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 36 0.15
gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like ... 35 0.25
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 35 0.33
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 35 0.33
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 34 0.43
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 34 0.43
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa... 34 0.56
gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo sap... 34 0.56
gi|31657117 SMEK homolog 1, suppressor of mek1 [Homo sapiens] 33 0.73
>gi|144227752 GRAM domain containing 1B [Homo sapiens]
Length = 738
Score = 1503 bits (3891), Expect = 0.0
Identities = 738/738 (100%), Positives = 738/738 (100%)
Query: 1 MKGFKLSCTASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQG 60
MKGFKLSCTASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQG
Sbjct: 1 MKGFKLSCTASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQG 60
Query: 61 VQRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQ 120
VQRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQ
Sbjct: 61 VQRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQ 120
Query: 121 RDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEK 180
RDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEK
Sbjct: 121 RDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEK 180
Query: 181 HFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDD 240
HFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDD
Sbjct: 181 HFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDD 240
Query: 241 DFNTMGYCEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFD 300
DFNTMGYCEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFD
Sbjct: 241 DFNTMGYCEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFD 300
Query: 301 GLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAPVNSPSLDFNDNEDIPTELSDSSDTHD 360
GLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAPVNSPSLDFNDNEDIPTELSDSSDTHD
Sbjct: 301 GLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAPVNSPSLDFNDNEDIPTELSDSSDTHD 360
Query: 361 EGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFQRDFMEQRRFSDIIFHPWKKEE 420
EGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFQRDFMEQRRFSDIIFHPWKKEE
Sbjct: 361 EGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFQRDFMEQRRFSDIIFHPWKKEE 420
Query: 421 NGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYT 480
NGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYT
Sbjct: 421 NGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYT 480
Query: 481 INRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKTES 540
INRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKTES
Sbjct: 481 INRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKTES 540
Query: 541 TYLAEMHRQSPKEKASKTTTVRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIKHVAG 600
TYLAEMHRQSPKEKASKTTTVRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIKHVAG
Sbjct: 541 TYLAEMHRQSPKEKASKTTTVRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIKHVAG 600
Query: 601 STQTRHIPEDTPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLT 660
STQTRHIPEDTPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLT
Sbjct: 601 STQTRHIPEDTPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLT 660
Query: 661 AWQGLRLQERLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSLINLQNG 720
AWQGLRLQERLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSLINLQNG
Sbjct: 661 AWQGLRLQERLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSLINLQNG 720
Query: 721 IRSRDYTSESEEKRNRYH 738
IRSRDYTSESEEKRNRYH
Sbjct: 721 IRSRDYTSESEEKRNRYH 738
>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
Length = 724
Score = 634 bits (1634), Expect = 0.0
Identities = 347/731 (47%), Positives = 471/731 (64%), Gaps = 38/731 (5%)
Query: 9 TASNSNRSTPACSPILRKRSR-----SPTPQNQDGDTMVEKGSDHSSDKS--PSTPEQGV 61
T +S RSTP+ SP LRKR + P P+ + G TMVEKGSD SS+K P TP
Sbjct: 4 TTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPG-TMVEKGSDSSSEKGGVPGTP---- 58
Query: 62 QRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQR 121
S S R+ +NSKK QSWY++LSPTYKQRNEDFRKLF +LP+ ERLIVDYSCALQR
Sbjct: 59 --STQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQR 116
Query: 122 DILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKH 181
+ILLQGRLYLSENWICFYSNIFRWET ++++LK++ + KEKTA+LIPNAIQ+CT+SEKH
Sbjct: 117 EILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKH 176
Query: 182 FFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDDD 241
FFTSFGARDR ++++FRLWQNALLEK L P+ELWH VHQCYG+ELGLTS+DEDYV P
Sbjct: 177 FFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSP-LQ 235
Query: 242 FNTMGYCEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDG 301
N +G +E+ + ++D +S + + + SP ++ L S SS+A +
Sbjct: 236 LNGLGTPKEVG-DVIALSDITSSGAADRSQEPSPVGSRRGHVTPNL-SRASSDADHGAEE 293
Query: 302 LPLEEEALEGDGSLEKEL--AIDNIMGEKIEMIAPVNSPSLDFNDNEDIPTELSD-SSDT 358
E+ + D S + + + E + P LD +E++ T+ S+ SS T
Sbjct: 294 DKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSST 353
Query: 359 HDEGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFQRDFMEQRRFSDIIFHPWKK 418
+E ++ A DLSGR +N VF+ ++L +LF++SPF + F++Q +F+D+ PW
Sbjct: 354 GEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSG 413
Query: 419 EENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYF 478
+ +Q RV+ YTI ++NPL PK+A+V ETQT+++ ++ V+D+EVLT +PY DYF
Sbjct: 414 DSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYF 473
Query: 479 YTINRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKT 538
YT +RY + +ARNK+RLRVS+E+RYRKQPW LVK+ IEKN WSG+EDYF HLE ELAK
Sbjct: 474 YTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKA 533
Query: 539 ESTYLAEMHRQSPKEKASKTTTVRRRKRP---HAHLRVPHLEEVMSPVTTPTDEDVGHRI 595
E L E K+ + +RRRKRP AH P P +
Sbjct: 534 EKLSLEE----GGKDARGLLSGLRRRKRPLSWRAHGDGPQ---------HPDPDPCARAG 580
Query: 596 KHVAGSTQTRHIPEDTPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYT 655
H +GS +R G + L++IS VIC SL++L+ LN++LFY+LW LE T
Sbjct: 581 IHTSGSLSSRFSEPSVDQG-PGAGIPSALVLISIVICVSLIILIALNVLLFYRLWSLERT 639
Query: 656 TQTLTAWQGLRLQE-RLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSL 714
T +W L L + + PQ+ TEWA++L Q+++H E+ KWR+I+++SV LLD+MK SL
Sbjct: 640 AHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSL 699
Query: 715 INLQNGIRSRD 725
L GI D
Sbjct: 700 EKLHQGITVSD 710
>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
Length = 713
Score = 602 bits (1553), Expect = e-172
Identities = 339/731 (46%), Positives = 460/731 (62%), Gaps = 49/731 (6%)
Query: 9 TASNSNRSTPACSPILRKRSR-----SPTPQNQDGDTMVEKGSDHSSDKS--PSTPEQGV 61
T +S RSTP+ SP LRKR + P P+ + G TMVEKGSD SS+K P TP
Sbjct: 4 TTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPG-TMVEKGSDSSSEKGGVPGTP---- 58
Query: 62 QRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQR 121
S S R+ +NSK +LSPTYKQRNEDFRKLF +LP+ ERLIVDYSCALQR
Sbjct: 59 --STQSLGSRNFIRNSK-------MLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQR 109
Query: 122 DILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKH 181
+ILLQGRLYLSENWICFYSNIFRWET ++++LK++ + KEKTA+LIPNAIQ+CT+SEKH
Sbjct: 110 EILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKH 169
Query: 182 FFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDDD 241
FFTSFGARDR ++++FRLWQNALLEK L P+ELWH VHQCYG+ELGLTS+DEDYV P
Sbjct: 170 FFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSP-LQ 228
Query: 242 FNTMGYCEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDG 301
N +G +E+ + ++D +S + + + SP ++ L S SS+A +
Sbjct: 229 LNGLGTPKEVG-DVIALSDITSSGAADRSQEPSPVGSRRGHVTPNL-SRASSDADHGAEE 286
Query: 302 LPLEEEALEGDGSLEKEL--AIDNIMGEKIEMIAPVNSPSLDFNDNEDIPTELSD-SSDT 358
E+ + D S + + + E + P LD +E++ T+ S+ SS T
Sbjct: 287 DKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSST 346
Query: 359 HDEGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFQRDFMEQRRFSDIIFHPWKK 418
+E ++ A DLSGR +N VF+ ++L +LF++SPF + F++Q +F+D+ PW
Sbjct: 347 GEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSG 406
Query: 419 EENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYF 478
+ +Q RV+ YTI ++NPL PK+A+V ETQT+++ ++ V+D+EVLT +PY DYF
Sbjct: 407 DSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYF 466
Query: 479 YTINRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKT 538
YT +RY + +ARNK+RLRVS+E+RYRKQPW LVK+ IEKN WSG+EDYF HLE ELAK
Sbjct: 467 YTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKA 526
Query: 539 ESTYLAEMHRQSPKEKASKTTTVRRRKRP---HAHLRVPHLEEVMSPVTTPTDEDVGHRI 595
E L E K+ + +RRRKRP AH P P +
Sbjct: 527 EKLSLEE----GGKDARGLLSGLRRRKRPLSWRAHGDGPQ---------HPDPDPCARAG 573
Query: 596 KHVAGSTQTRHIPEDTPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYT 655
H +GS +R G S L+L I L++L+ LN++LFY+LW LE T
Sbjct: 574 IHTSGSLSSRFSEPSVDQGPGAGIPSALVL-----ISIVLIILIALNVLLFYRLWSLERT 628
Query: 656 TQTLTAWQGLRLQE-RLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSL 714
T +W L L + + PQ+ TEWA++L Q+++H E+ KWR+I+++SV LLD+MK SL
Sbjct: 629 AHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSL 688
Query: 715 INLQNGIRSRD 725
L GI D
Sbjct: 689 EKLHQGITVSD 699
>gi|187936935 GRAM domain containing 1C [Homo sapiens]
Length = 662
Score = 466 bits (1199), Expect = e-131
Identities = 276/687 (40%), Positives = 397/687 (57%), Gaps = 61/687 (8%)
Query: 37 DGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW-YNVLSPTYKQRN 95
D + D + SP+ E V + G S W + + S TYK RN
Sbjct: 15 DSSLATDLQEDVEENPSPTVEENNVVVK------KQGPNLHNWSGDWSFWISSSTYKDRN 68
Query: 96 EDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKD 155
E++R+ F LPDTERLI DY+CALQRDILLQGRLYLSENW+CFYSNIFRWET +++ LK+
Sbjct: 69 EEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKN 128
Query: 156 ICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELW 215
I MTKEKTARLIPNAIQ+ T+SEK FFTSFGARDR+Y+ +FRLWQN LL+K L +E W
Sbjct: 129 ITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFW 188
Query: 216 HFVHQCYGNELGLTSDDEDYVPPDDDFNTMGYCEEIPVEENEVNDSSSKSSIETKPDASP 275
+ Q YG ELGL +++ + + + +E+ + S +SS++ +
Sbjct: 189 QLLQQNYGTELGLNAEEMENL-------------SLSIEDVQPR-SPGRSSLDDSGERDE 234
Query: 276 QLPKK-SITNSTLTSTGSSEAPVSFDGLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAP 334
+L K S T+ +++ +E SFDG + L + S ++ +++ + +
Sbjct: 235 KLSKSISFTSESISRVSETE---SFDG-NSSKGGLGKEESQNEKQTKKSLLPTLEKKLTR 290
Query: 335 VNSPSLDFNDNEDIPTELSDSSDTHDEGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT 394
V S SLD N NE + + S +SD+ DE V +DL GR ++N +F+ S D++++LLFT
Sbjct: 291 VPSKSLDLNKNEYLSLDKSSTSDSVDEENVPE--KDLHGRLFINRIFHISADRMFELLFT 348
Query: 395 NSPFQRDFMEQRRFSDIIFHPWKKEENGNQSRVILYTITLTNPLAPKTATVRETQTMYKA 454
+S F + F R D++ PW E G+Q R + YTI L +PL K E QT+YK
Sbjct: 349 SSRFMQKFASSRNIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTAATEKQTLYKE 408
Query: 455 SQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARNKSRLRVSTELRYRKQPWGLVKT 514
S+E+ Y++D+EVLTHDVPYHDYFYT+NRY + R ++ K RLRVST+L+YRKQPWGLVK+
Sbjct: 409 SREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKS 468
Query: 515 FIEKNFWSGLEDYFRHLESELAKTESTYLAEMHRQSPKEKASKTTTVRRRKRPHAHL--R 572
IEKN WS LEDYF+ LES+L ES E K T +RRR+R
Sbjct: 469 LIEKNSWSSLEDYFKQLESDLLIEESVL------NQAIEDPGKLTGLRRRRRTFNRTAET 522
Query: 573 VPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPEDTPNGFHLQSVSKLLLVISCVIC 632
VP L +H +G + T +++ + L+V+ +
Sbjct: 523 VPKLSS-----------------QHSSGDVGLGAKGDITGKKKEMENYNVTLIVVMSIF- 564
Query: 633 FSLVLLVILNMMLFYKLWMLEYTTQTLTAWQGLRLQERLPQS-QTEWAQLLESQQKYHDT 691
++LLV+LN+ LF KL +E+ Q ++ LRLQE + ++ E+ QK D
Sbjct: 565 --VLLLVLLNVTLFLKLSKIEHAAQ---SFYRLRLQEEKSLNLASDMVSRAETIQKNKD- 618
Query: 692 ELQKWREIIKSSVMLLDQMKDSLINLQ 718
+ + + +++ S+++L+Q+K SLI LQ
Sbjct: 619 QAHRLKGVLRDSIVMLEQLKSSLIMLQ 645
>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
Length = 416
Score = 100 bits (248), Expect = 6e-21
Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 13/173 (7%)
Query: 28 SRSPTPQ----NQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW 83
++SPTP + D ++ S S D + ++ C ++S KKS S
Sbjct: 31 AQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKN---DCKTESKNDPKTERKKSSS- 86
Query: 84 YNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIF 143
S YK N F KLF +P E L ++CALQ++IL QG+L++SENWICF+S +F
Sbjct: 87 ----SSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVF 141
Query: 144 RWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMM 196
+T +++ + + K KTA L+PNA+ + T ++++ F S +RD TY ++
Sbjct: 142 GKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 194
>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
Length = 447
Score = 100 bits (248), Expect = 6e-21
Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 13/173 (7%)
Query: 28 SRSPTPQ----NQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW 83
++SPTP + D ++ S S D + ++ C ++S KKS S
Sbjct: 62 AQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKN---DCKTESKNDPKTERKKSSS- 117
Query: 84 YNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIF 143
S YK N F KLF +P E L ++CALQ++IL QG+L++SENWICF+S +F
Sbjct: 118 ----SSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVF 172
Query: 144 RWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMM 196
+T +++ + + K KTA L+PNA+ + T ++++ F S +RD TY ++
Sbjct: 173 GKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 225
>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
Length = 432
Score = 100 bits (248), Expect = 6e-21
Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 13/173 (7%)
Query: 28 SRSPTPQ----NQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW 83
++SPTP + D ++ S S D + ++ C ++S KKS S
Sbjct: 47 AQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKN---DCKTESKNDPKTERKKSSS- 102
Query: 84 YNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIF 143
S YK N F KLF +P E L ++CALQ++IL QG+L++SENWICF+S +F
Sbjct: 103 ----SSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVF 157
Query: 144 RWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMM 196
+T +++ + + K KTA L+PNA+ + T ++++ F S +RD TY ++
Sbjct: 158 GKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 210
>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
Length = 440
Score = 99.4 bits (246), Expect = 1e-20
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Query: 51 DKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTER 110
D+ + G + ++ KN K++ + S YK N F KLF +P E
Sbjct: 74 DQESKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKA-NMHFHKLFLSVPTEEP 132
Query: 111 LIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPN 170
L ++CALQ++IL QG+L++SENWICF+S +F +T +++ + + K KTA L+PN
Sbjct: 133 LKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPN 192
Query: 171 AIQVCTDSEKHFFTSFGARDRTYMMM 196
A+ + T ++++ F S +RD TY ++
Sbjct: 193 ALIIATVTDRYIFVSLLSRDSTYKLL 218
>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
Length = 328
Score = 93.6 bits (231), Expect = 6e-19
Identities = 42/102 (41%), Positives = 68/102 (66%)
Query: 95 NEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLK 154
N F KLF +P E L ++CALQ++IL QG+L++SENWICF+S +F +T +++
Sbjct: 5 NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAF 64
Query: 155 DICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMM 196
+ + K KTA L+PNA+ + T ++++ F S +RD TY ++
Sbjct: 65 SVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 106
>gi|60593095 GRAM domain containing 2 [Homo sapiens]
Length = 354
Score = 92.0 bits (227), Expect = 2e-18
Identities = 44/111 (39%), Positives = 72/111 (64%), Gaps = 1/111 (0%)
Query: 90 TYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLL 149
T + N+ + KLFK +P E ++ SCALQRD LLQGRLY+S NW+CF++++F + +
Sbjct: 66 TLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKV 125
Query: 150 TVRLKDICSMTKEKTARLIPNAIQVCTD-SEKHFFTSFGARDRTYMMMFRL 199
+ + + + K K ARL+PN + + T+ S+K+ F S +RD Y ++ R+
Sbjct: 126 VIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRV 176
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 65.5 bits (158), Expect = 2e-10
Identities = 40/110 (36%), Positives = 64/110 (58%), Gaps = 3/110 (2%)
Query: 91 YKQRNEDFRKLFKQLPDTERLIVDYSCALQRD-ILLQGRLYLSENWICFYSNIFRWETLL 149
+K+ F +LF +P+ E+L+ YSC+ + + QG +YLS N +CFYS + E L
Sbjct: 141 FKEAIVKFHRLFG-MPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKL 199
Query: 150 TVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMMFRL 199
+R DI + K T L+P+ I+V T S +HFF+ F + T+ +M +L
Sbjct: 200 VIRWVDITQLEKNATL-LLPDVIKVSTRSSEHFFSVFLNINETFKLMEQL 248
Score = 37.7 bits (86), Expect = 0.039
Identities = 27/109 (24%), Positives = 59/109 (54%), Gaps = 10/109 (9%)
Query: 92 KQRNEDFRKLFKQLPDTERLIVDYSCALQ---RDILLQGRLYLSENWICFYSNIFRWETL 148
+ ++E +R LF+ LP E+L C L + + G++++S N+ICF S + E L
Sbjct: 289 RAKSERYRALFR-LPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTS---KEENL 344
Query: 149 --LTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMM 195
L + L+++ + K ++ ++P+ + + T + F + +DR +++
Sbjct: 345 CSLIIPLREVTIVEKADSSSVLPSPLSISTRNRMTFLFA-NLKDRDFLV 392
>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
isoform b [Homo sapiens]
Length = 632
Score = 60.5 bits (145), Expect = 6e-09
Identities = 38/109 (34%), Positives = 63/109 (57%), Gaps = 5/109 (4%)
Query: 98 FRKLFKQLPDTERLIVDYSCALQRD-ILLQGRLYLSENWICFYSNIFRWETLLTVRLKDI 156
F K F LP+ E+L+ YSC+ + + QG LYLS N++ FYS + E L + ++
Sbjct: 147 FEKCFG-LPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEV 205
Query: 157 CSMTKEKTARLI-PNAIQVCTDSEKHFFTSFGARDRTYMMMFRLWQNAL 204
+ EKT+ +I +I VC+ E H+F+ F ++TY++M +L A+
Sbjct: 206 SKL--EKTSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQLANYAI 252
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 60.5 bits (145), Expect = 6e-09
Identities = 38/109 (34%), Positives = 63/109 (57%), Gaps = 5/109 (4%)
Query: 98 FRKLFKQLPDTERLIVDYSCALQRD-ILLQGRLYLSENWICFYSNIFRWETLLTVRLKDI 156
F K F LP+ E+L+ YSC+ + + QG LYLS N++ FYS + E L + ++
Sbjct: 147 FEKCFG-LPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEV 205
Query: 157 CSMTKEKTARLI-PNAIQVCTDSEKHFFTSFGARDRTYMMMFRLWQNAL 204
+ EKT+ +I +I VC+ E H+F+ F ++TY++M +L A+
Sbjct: 206 SKL--EKTSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQLANYAI 252
>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
isoform b [Homo sapiens]
Length = 1233
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/110 (34%), Positives = 60/110 (54%), Gaps = 3/110 (2%)
Query: 91 YKQRNEDFRKLFKQLPDTERLIVDYSCALQRD-ILLQGRLYLSENWICFYSNIFRWETLL 149
+K+ RK F +P+ E+L+ YSC+ + + QG LYL+ N +CFYS + E L
Sbjct: 137 FKEAELKMRKQFG-MPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSL 195
Query: 150 TVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMMFRL 199
V+ DI + K T L P +I+V T ++ FF+ F T+ +M +L
Sbjct: 196 VVQWVDITRLEKNATL-LFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/107 (26%), Positives = 57/107 (53%), Gaps = 6/107 (5%)
Query: 92 KQRNEDFRKLFKQLPDTERLIVDYSCALQ---RDILLQGRLYLSENWICFYSNIFRWETL 148
+ +NE +R F+ LP ERL SC L + + G++++S N+ICF S
Sbjct: 284 RAKNECYRATFR-LPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASK-EEDACH 341
Query: 149 LTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMM 195
L + L+++ + K ++ ++P+ + + T S+ F + +DR +++
Sbjct: 342 LIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFA-NLKDRDFLV 387
>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1250
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/110 (34%), Positives = 60/110 (54%), Gaps = 3/110 (2%)
Query: 91 YKQRNEDFRKLFKQLPDTERLIVDYSCALQRD-ILLQGRLYLSENWICFYSNIFRWETLL 149
+K+ RK F +P+ E+L+ YSC+ + + QG LYL+ N +CFYS + E L
Sbjct: 137 FKEAELKMRKQFG-MPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSL 195
Query: 150 TVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMMFRL 199
V+ DI + K T L P +I+V T ++ FF+ F T+ +M +L
Sbjct: 196 VVQWVDITRLEKNATL-LFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/107 (26%), Positives = 57/107 (53%), Gaps = 6/107 (5%)
Query: 92 KQRNEDFRKLFKQLPDTERLIVDYSCALQ---RDILLQGRLYLSENWICFYSNIFRWETL 148
+ +NE +R F+ LP ERL SC L + + G++++S N+ICF S
Sbjct: 284 RAKNECYRATFR-LPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASK-EEDACH 341
Query: 149 LTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMM 195
L + L+++ + K ++ ++P+ + + T S+ F + +DR +++
Sbjct: 342 LIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFA-NLKDRDFLV 387
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/96 (32%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 106 PDTERLIVDYSCALQRD-ILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKT 164
P+ E+L+ YSC + + QG LYLS N +CFYS E L V DI + E+T
Sbjct: 154 PEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKL--ERT 211
Query: 165 ARL-IPNAIQVCTDSEKHFFTSFGARDRTYMMMFRL 199
+ + + + I++ T +++ F+ F D + +M +L
Sbjct: 212 SNVFLTDTIRITTQNKERDFSMFLNLDEVFKVMEQL 247
Score = 39.7 bits (91), Expect = 0.010
Identities = 60/251 (23%), Positives = 112/251 (44%), Gaps = 28/251 (11%)
Query: 92 KQRNEDFRKLFKQLPDTERLIVDYSCALQRDIL---LQGRLYLSENWICFYSNIFRWETL 148
+ +NE FR F+ LP E+L C+L GR++ S+++ICF S +
Sbjct: 281 RAQNEFFRAFFR-LPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKI 339
Query: 149 LTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMMFRLWQNALLEKP 208
+ + L+++ S+ K + L+P+ I V S K F RDR ++L+E
Sbjct: 340 I-LPLREVVSIEKMEDTSLLPHPIIVSIRS-KVAFQFIELRDR----------DSLVEAL 387
Query: 209 LCPKELWHFVHQCYGNELGLTSDDEDYVPPDDDFNTMGYCEEIPVEENEVNDSSSKSSIE 268
L + H H + + TS D+D F++ C + + E+ SS++S E
Sbjct: 388 LARLKQVHANHPVHYD----TSADDDMA--SLVFHSTSMCSDHRFGDLEM--MSSQNSEE 439
Query: 269 TKPDASPQL-PKKSITNSTLTSTGSSEAPVSFDGLPLEEEALEGDGSLEKELAIDNIMGE 327
++ + SP + P +T + + S ++ +S + + + +L D +E + E
Sbjct: 440 SEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKI---SLWNDHFVEYGRTVCMFRTE 496
Query: 328 KIEMIAPVNSP 338
KI + + P
Sbjct: 497 KIRKLVAMGIP 507
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 36.2 bits (82), Expect = 0.11
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 11 SNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSG 70
SN++R P P L KR + ++G V K S +SP E+ +++ S SG
Sbjct: 1486 SNNDREVP---PDLTKRRKE-----ENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSG 1537
Query: 71 RSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQ 104
+ G +S KS+ + S K+ D K+ K+
Sbjct: 1538 KEKGSDSFKSEKMDKISSGGKKESRHDKEKIEKK 1571
>gi|46409326 C-type lectin domain family 9, member A [Homo sapiens]
Length = 241
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 623 LLLVISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLTAWQGLRLQERLPQSQTEWAQLL 682
L++VISCV C L L +F + +L+ +T + + L QER + TEW +
Sbjct: 35 LVMVISCVFCMGL-----LTASIFLGVKLLQVSTIAMQQQEKLIQQERALLNFTEWKRSC 89
Query: 683 ESQQKYHDTELQ 694
Q KY +Q
Sbjct: 90 ALQMKYCQAFMQ 101
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 35.8 bits (81), Expect = 0.15
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 8/81 (9%)
Query: 262 SSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAP-VSFDGL--PLEEEALEGDGSLEKE 318
SS++S TK SP P+ S TNS TS ++ AP +G+ PLE+E E E++
Sbjct: 1528 SSRASSPTK--TSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAENQ---EEK 1582
Query: 319 LAIDNIMGEKIEMIAPVNSPS 339
++ +GEK+E A SP+
Sbjct: 1583 PEKNSRIGEKMETEADAPSPA 1603
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 35.8 bits (81), Expect = 0.15
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 8/81 (9%)
Query: 262 SSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAP-VSFDGL--PLEEEALEGDGSLEKE 318
SS++S TK SP P+ S TNS TS ++ AP +G+ PLE+E E E++
Sbjct: 1528 SSRASSPTK--TSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAENQ---EEK 1582
Query: 319 LAIDNIMGEKIEMIAPVNSPS 339
++ +GEK+E A SP+
Sbjct: 1583 PEKNSRIGEKMETEADAPSPA 1603
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 35.8 bits (81), Expect = 0.15
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 8/81 (9%)
Query: 262 SSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAP-VSFDGL--PLEEEALEGDGSLEKE 318
SS++S TK SP P+ S TNS TS ++ AP +G+ PLE+E E E++
Sbjct: 1587 SSRASSPTK--TSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAENQ---EEK 1641
Query: 319 LAIDNIMGEKIEMIAPVNSPS 339
++ +GEK+E A SP+
Sbjct: 1642 PEKNSRIGEKMETEADAPSPA 1662
>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
Length = 1597
Score = 35.8 bits (81), Expect = 0.15
Identities = 51/219 (23%), Positives = 85/219 (38%), Gaps = 51/219 (23%)
Query: 153 LKDIC--------SMTKEKTARLIPNA---IQVCTDSEKHFFT---SFGARDRTYMMMFR 198
L+D+C S KE +A + PN + D+ +H+ S R +
Sbjct: 64 LRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPE 123
Query: 199 LWQNALLEKPLCPKELWHFVHQCYGNELG-----------LTS--------DDEDYVPPD 239
LW CP + H + ++LG LTS ++E+ D
Sbjct: 124 LWA--------CPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSD 175
Query: 240 DDFNTMGY--CEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPV 297
+ T Y CEE P E N+ N+ S +I +LP + + S +
Sbjct: 176 NSGQTRYYSPCEEHPAETNQ-NEGSESGTIRQ----GEELPPEELQESQGLLHPQEVQVL 230
Query: 298 SFDGLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAPVN 336
G +E G+G+L +++ D ++GE+ +MI VN
Sbjct: 231 EEQGQ--QEAGFRGEGTLREDVCADGLLGEE-QMIEQVN 266
>gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like
[Homo sapiens]
Length = 484
Score = 35.0 bits (79), Expect = 0.25
Identities = 50/219 (22%), Positives = 85/219 (38%), Gaps = 51/219 (23%)
Query: 153 LKDIC--------SMTKEKTARLIPNA---IQVCTDSEKHFFT---SFGARDRTYMMMFR 198
L+D+C S KE +A + PN + D+ +H+ S R +
Sbjct: 64 LRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPE 123
Query: 199 LWQNALLEKPLCPKELWHFVHQCYGNELG-----------LTS--------DDEDYVPPD 239
LW CP + H + ++LG LTS ++E+ D
Sbjct: 124 LWA--------CPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSD 175
Query: 240 DDFNTMGY--CEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPV 297
+ T Y CEE P E N+ N+ + +I +LP + + S +
Sbjct: 176 NSGQTRYYSPCEEHPAETNQ-NEGAESGTIRQ----GEELPSEELQESQGLLHPQEVQVL 230
Query: 298 SFDGLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAPVN 336
G +E G+G+L +++ D ++GE+ +MI VN
Sbjct: 231 EEQGQ--QEAGFRGEGTLREDVCADGLLGEE-QMIEQVN 266
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 34.7 bits (78), Expect = 0.33
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 12 NSNRSTPACSPILRKRSRSPTPQNQD-GDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSG 70
+S+RS I RK SRSP+P++++ D EK DH S++ +++S + + G
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 563
Query: 71 RSGGKNSKKSQS 82
+ K K S S
Sbjct: 564 KE--KLEKNSTS 573
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 34.7 bits (78), Expect = 0.33
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 12 NSNRSTPACSPILRKRSRSPTPQNQD-GDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSG 70
+S+RS I RK SRSP+P++++ D EK DH S++ +++S + + G
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 447
Query: 71 RSGGKNSKKSQS 82
+ K K S S
Sbjct: 448 KE--KLEKNSTS 457
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 34.3 bits (77), Expect = 0.43
Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 29 RSPTPQNQ----DGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSWY 84
R+PT Q+ DG+ ++ + H+S SP E+G ++S S S + G ++ S
Sbjct: 68 RTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLA 127
Query: 85 NVLSPTYKQR--NEDFRKLFKQLPDTERLI 112
+V+ T KQR E + ++ P E+L+
Sbjct: 128 DVVD-TLKQRKMEELIKNEPEETPSIEKLL 156
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 34.3 bits (77), Expect = 0.43
Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 29 RSPTPQNQ----DGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSWY 84
R+PT Q+ DG+ ++ + H+S SP E+G ++S S S + G ++ S
Sbjct: 81 RTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLA 140
Query: 85 NVLSPTYKQR--NEDFRKLFKQLPDTERLI 112
+V+ T KQR E + ++ P E+L+
Sbjct: 141 DVVD-TLKQRKMEELIKNEPEETPSIEKLL 169
>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
sapiens]
Length = 941
Score = 33.9 bits (76), Expect = 0.56
Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 42 VEKGSDHSSDKSPSTPEQGVQRSCS---SQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDF 98
V++G SS K S+ +G S SQSG SG K KK++ + L + K +E+F
Sbjct: 636 VDRGK-RSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDCLLGSAK-LDEEF 693
Query: 99 RKLFKQLPDTERLIVDYSC 117
K F LP + D C
Sbjct: 694 EKKFNSLPQYSPVTFDRKC 712
>gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo
sapiens]
Length = 911
Score = 33.9 bits (76), Expect = 0.56
Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 42 VEKGSDHSSDKSPSTPEQGVQRSCS---SQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDF 98
V++G SS K S+ +G S SQSG SG K KK++ + L + K +E+F
Sbjct: 636 VDRGK-RSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDCLLGSAK-LDEEF 693
Query: 99 RKLFKQLPDTERLIVDYSC 117
K F LP + D C
Sbjct: 694 EKKFNSLPQYSPVTFDRKC 712
>gi|31657117 SMEK homolog 1, suppressor of mek1 [Homo sapiens]
Length = 820
Score = 33.5 bits (75), Expect = 0.73
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 229 TSDDEDYVPPDDDFNTMGYCEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT 288
T +D+D + P F E ++E+E + K+++ + S +L S T + LT
Sbjct: 690 TKNDDDIMDPISKF-----MERKKLKESEEKEVLLKTNLSGRQSPSFKLSLSSGTKTNLT 744
Query: 289 STGSSEAPVSFDGLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAPVNSPSLDFNDNEDI 348
S S+ G P + GS+ K + + K ++ V+ P D +D+ED
Sbjct: 745 SQSSTTNLPGSPGSPGSPGSPGSPGSVPKNTSQTAAITTKGGLVGLVDYPDDDEDDDED- 803
Query: 349 PTELSDSSDT 358
D DT
Sbjct: 804 ----EDKEDT 809
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,038,639
Number of Sequences: 37866
Number of extensions: 1369987
Number of successful extensions: 6103
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 5935
Number of HSP's gapped (non-prelim): 209
length of query: 738
length of database: 18,247,518
effective HSP length: 110
effective length of query: 628
effective length of database: 14,082,258
effective search space: 8843658024
effective search space used: 8843658024
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.