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Search of human proteins with 109689718
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109689718 abhydrolase domain containing 12 isoform a [Homo
sapiens]
(398 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109689718 abhydrolase domain containing 12 isoform a [Homo sa... 832 0.0
gi|24308097 abhydrolase domain containing 12 isoform b [Homo sap... 806 0.0
gi|32451492 abhydrolase domain containing 12B isoform b [Homo sa... 252 5e-67
gi|32528310 abhydrolase domain containing 12B isoform c [Homo sa... 243 2e-64
gi|49355781 abhydrolase domain containing 13 [Homo sapiens] 72 7e-13
gi|239741293 PREDICTED: hypothetical protein XP_002342156 [Homo ... 64 3e-10
gi|169215908 PREDICTED: family with sequence similarity 108, mem... 63 4e-10
gi|169215726 PREDICTED: family with sequence similarity 108, mem... 63 4e-10
gi|239746656 PREDICTED: hypothetical protein LOC729495 [Homo sap... 63 4e-10
gi|194306564 hypothetical protein LOC81926 isoform 2 [Homo sapiens] 63 5e-10
gi|194306562 hypothetical protein LOC81926 isoform 1 [Homo sapiens] 61 2e-09
gi|239753043 PREDICTED: hypothetical protein [Homo sapiens] 60 5e-09
gi|151301175 hypothetical protein LOC58489 [Homo sapiens] 57 4e-08
gi|71051602 family with sequence similarity 108, member B1 isofo... 56 5e-08
gi|71051600 family with sequence similarity 108, member B1 isofo... 56 5e-08
gi|8923001 abhydrolase domain containing 10 [Homo sapiens] 39 0.006
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 34 0.27
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 34 0.27
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 34 0.27
gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens] 34 0.27
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 34 0.27
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 34 0.27
gi|221316588 biphenyl hydrolase-like [Homo sapiens] 33 0.45
gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens] 32 1.0
gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens] 32 1.0
gi|23397663 alpha/beta hydrolase domain containing protein 3 [Ho... 32 1.0
gi|26051273 voltage-gated potassium channel, subfamily H, member... 30 5.0
gi|26051271 voltage-gated potassium channel, subfamily H, member... 30 5.0
gi|4557729 voltage-gated potassium channel, subfamily H, member ... 30 5.0
gi|218777837 abhydrolase domain containing 7 [Homo sapiens] 30 5.0
>gi|109689718 abhydrolase domain containing 12 isoform a [Homo
sapiens]
Length = 398
Score = 832 bits (2149), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MRKRTEPVALEHERCAAAGSSSSGSAAAALDADCRLKQNLRLTGPAAAEPRCAADAGMKR 60
MRKRTEPVALEHERCAAAGSSSSGSAAAALDADCRLKQNLRLTGPAAAEPRCAADAGMKR
Sbjct: 1 MRKRTEPVALEHERCAAAGSSSSGSAAAALDADCRLKQNLRLTGPAAAEPRCAADAGMKR 60
Query: 61 ALGRRKGVWLRLRKILFCVLGLYIAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQ 120
ALGRRKGVWLRLRKILFCVLGLYIAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQ
Sbjct: 61 ALGRRKGVWLRLRKILFCVLGLYIAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQ 120
Query: 121 GLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGT 180
GLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGT
Sbjct: 121 GLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGT 180
Query: 181 RGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPV 240
RGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPV
Sbjct: 181 RGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPV 240
Query: 241 YIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWF 300
YIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWF
Sbjct: 241 YIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWF 300
Query: 301 FLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQ 360
FLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQ
Sbjct: 301 FLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQ 360
Query: 361 FVPFHSDLGYRHKYIYKSPELPRILREFLGKSEPEHQH 398
FVPFHSDLGYRHKYIYKSPELPRILREFLGKSEPEHQH
Sbjct: 361 FVPFHSDLGYRHKYIYKSPELPRILREFLGKSEPEHQH 398
>gi|24308097 abhydrolase domain containing 12 isoform b [Homo
sapiens]
Length = 404
Score = 806 bits (2081), Expect = 0.0
Identities = 386/386 (100%), Positives = 386/386 (100%)
Query: 1 MRKRTEPVALEHERCAAAGSSSSGSAAAALDADCRLKQNLRLTGPAAAEPRCAADAGMKR 60
MRKRTEPVALEHERCAAAGSSSSGSAAAALDADCRLKQNLRLTGPAAAEPRCAADAGMKR
Sbjct: 1 MRKRTEPVALEHERCAAAGSSSSGSAAAALDADCRLKQNLRLTGPAAAEPRCAADAGMKR 60
Query: 61 ALGRRKGVWLRLRKILFCVLGLYIAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQ 120
ALGRRKGVWLRLRKILFCVLGLYIAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQ
Sbjct: 61 ALGRRKGVWLRLRKILFCVLGLYIAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQ 120
Query: 121 GLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGT 180
GLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGT
Sbjct: 121 GLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGT 180
Query: 181 RGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPV 240
RGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPV
Sbjct: 181 RGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPV 240
Query: 241 YIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWF 300
YIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWF
Sbjct: 241 YIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWF 300
Query: 301 FLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQ 360
FLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQ
Sbjct: 301 FLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQ 360
Query: 361 FVPFHSDLGYRHKYIYKSPELPRILR 386
FVPFHSDLGYRHKYIYKSPELPRILR
Sbjct: 361 FVPFHSDLGYRHKYIYKSPELPRILR 386
>gi|32451492 abhydrolase domain containing 12B isoform b [Homo
sapiens]
Length = 255
Score = 252 bits (643), Expect = 5e-67
Identities = 128/254 (50%), Positives = 172/254 (67%), Gaps = 3/254 (1%)
Query: 138 IGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGTRGGDHRVELYKVLSSLG 197
+G+WHTVP+ ++A+GKD WYE AL +PII+YLHG+A R HR++L KVLS G
Sbjct: 2 LGIWHTVPSCRGEDAKGKDCCWYEAALRDGNPIIVYLHGSAEHRAASHRLKLVKVLSDGG 61
Query: 198 YHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNLVR 257
+HV++ DYRG+GDS G P+E G+T DA+ V++W KARSG PV +WGHSLGTGVATN +
Sbjct: 62 FHVLSVDYRGFGDSTGKPTEEGLTTDAICVYEWTKARSGITPVCLWGHSLGTGVATNAAK 121
Query: 258 RLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDEN 317
L E+ P DA++LE+PFTN+ + ++P IYR PGF +D + I F NDEN
Sbjct: 122 VLEEKGCPVDAIVLEAPFTNMWVASINYPLLKIYRNIPGFLRTLMDALRKDKIIFPNDEN 181
Query: 318 VKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQFVPFHSDLGYRHKYIYK 377
VK +S PLLILH EDD VP + G+KLY IA A ++ +V+ V F G++H + K
Sbjct: 182 VKFLSSPLLILHGEDDRTVPLEYGKKLYEIARNAYRNKE-RVKMVIFPP--GFQHNLLCK 238
Query: 378 SPELPRILREFLGK 391
SP L +R+FL K
Sbjct: 239 SPTLLITVRDFLSK 252
>gi|32528310 abhydrolase domain containing 12B isoform c [Homo
sapiens]
Length = 285
Score = 243 bits (621), Expect = 2e-64
Identities = 126/250 (50%), Positives = 168/250 (67%), Gaps = 3/250 (1%)
Query: 142 HTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVV 201
HTVP+ ++A+GKD WYE AL +PII+YLHG+A R HR++L KVLS G+HV+
Sbjct: 36 HTVPSCRGEDAKGKDCCWYEAALRDGNPIIVYLHGSAEHRAASHRLKLVKVLSDGGFHVL 95
Query: 202 TFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCE 261
+ DYRG+GDS G P+E G+T DA+ V++W KARSG PV +WGHSLGTGVATN + L E
Sbjct: 96 SVDYRGFGDSTGKPTEEGLTTDAICVYEWTKARSGITPVCLWGHSLGTGVATNAAKVLEE 155
Query: 262 RETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDENVKHI 321
+ P DA++LE+PFTN+ + ++P IYR PGF +D + I F NDENVK +
Sbjct: 156 KGCPVDAIVLEAPFTNMWVASINYPLLKIYRNIPGFLRTLMDALRKDKIIFPNDENVKFL 215
Query: 322 SCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQFVPFHSDLGYRHKYIYKSPEL 381
S PLLILH EDD VP + G+KLY IA A ++ +V+ V F G++H + KSP L
Sbjct: 216 SSPLLILHGEDDRTVPLEYGKKLYEIARNAYRNKE-RVKMVIFPP--GFQHNLLCKSPTL 272
Query: 382 PRILREFLGK 391
+R+FL K
Sbjct: 273 LITVRDFLSK 282
>gi|49355781 abhydrolase domain containing 13 [Homo sapiens]
Length = 337
Score = 72.4 bits (176), Expect = 7e-13
Identities = 55/190 (28%), Positives = 94/190 (49%), Gaps = 18/190 (9%)
Query: 169 PIILYLHGNAGTRGGDHRV-ELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHV 227
P I+Y HGNAG G HR+ +L +L +++ DYRG+G S G SE G+ D+ V
Sbjct: 115 PTIIYFHGNAGNIG--HRLPNALLMLVNLKVNLLLVDYRGYGKSEGEASEEGLYLDSEAV 172
Query: 228 FDWIKARS--GDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSH 285
D++ R ++++G SLG VA +L R + A+++E+ F +I H
Sbjct: 173 LDYVMTRPDLDKTKIFLFGRSLGGAVAIHLASENSHRIS---AIMVENTFLSI-----PH 224
Query: 286 PFSVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
S ++ +FP P+ KF + + P L + D ++P + ++LY
Sbjct: 225 MASTLFSFFP----MRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLY 280
Query: 346 SIAAPARSFR 355
+ +P+R+ R
Sbjct: 281 EL-SPSRTKR 289
>gi|239741293 PREDICTED: hypothetical protein XP_002342156 [Homo
sapiens]
Length = 383
Score = 63.5 bits (153), Expect = 3e-10
Identities = 66/227 (29%), Positives = 99/227 (43%), Gaps = 47/227 (20%)
Query: 129 YLQPEEDVTIGVWHTVPAVWWKNAQG-KDQMWYEDALASSHPIILYLHGNAGTRGGDHRV 187
Y Q E D TI V+ T K+A+G + Y + + +L+ HGNA G
Sbjct: 151 YSQRELD-TIEVFPT------KSARGNRVSCMYVRCVPGARYTVLFSHGNAVDLG--QMS 201
Query: 188 ELYKVLSS-LGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNP--VYIWG 244
Y L S L ++ T+D G+G S G PSER + D + ++ R G +P + ++G
Sbjct: 202 SFYIGLGSRLHCNIFTYDSSGYGASSGRPSERNLYADIDATWQALRTRYGISPDSIILYG 261
Query: 245 HSLGTGVATNLVRRL-CERETPPDALILESPFTN-----IREEAKSHPFSVIYRYFPGFD 298
S+GT +L R C A++L SP T+ R+ K++ F
Sbjct: 262 QSIGTVPTMDLASRYECA------AVVLHSPLTSGMRVAFRDTKKTYCFDA--------- 306
Query: 299 WFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
F N E V I+ P+LI+H +D V+ F G LY
Sbjct: 307 -------------FPNIEKVSKITSPVLIIHGREDEVIDFSHGLALY 340
>gi|169215908 PREDICTED: family with sequence similarity 108, member
A5 [Homo sapiens]
Length = 403
Score = 63.2 bits (152), Expect = 4e-10
Identities = 64/221 (28%), Positives = 95/221 (42%), Gaps = 37/221 (16%)
Query: 129 YLQPEEDVTIGVWHTVPAVWWKNAQG-KDQMWYEDALASSHPIILYLHGNAGTRGGDHRV 187
Y Q E D TI V+ T K+A G + Y + + + + HGNA G
Sbjct: 173 YSQRELD-TIEVFPT------KSAHGNRVSCMYVRCVPGARYTVFFSHGNAVDLG--QMS 223
Query: 188 ELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNP--VYIWGH 245
Y L+S + + +DY G+G S G PSE + D + ++ R G +P + ++G
Sbjct: 224 SFYTGLNSRLHCNIIYDYSGYGASAGRPSEWNLYADIDAAWQALRTRYGISPDSIILYGQ 283
Query: 246 SLGTGVATNLVRRL-CERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDP 304
S+GT +L R C A++L SP T+ A FP + D
Sbjct: 284 SIGTVPTVDLASRYECA------AVVLHSPLTSGMRVA-----------FPDTKTYCFDA 326
Query: 305 ITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
F N E V I+ P+LI+H +D V+ F G LY
Sbjct: 327 -------FPNIEKVSKITSPVLIIHGMEDEVIDFSHGLALY 360
>gi|169215726 PREDICTED: family with sequence similarity 108, member
A5 [Homo sapiens]
Length = 403
Score = 63.2 bits (152), Expect = 4e-10
Identities = 64/221 (28%), Positives = 95/221 (42%), Gaps = 37/221 (16%)
Query: 129 YLQPEEDVTIGVWHTVPAVWWKNAQG-KDQMWYEDALASSHPIILYLHGNAGTRGGDHRV 187
Y Q E D TI V+ T K+A G + Y + + + + HGNA G
Sbjct: 173 YSQRELD-TIEVFPT------KSAHGNRVSCMYVRCVPGARYTVFFSHGNAVDLG--QMS 223
Query: 188 ELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNP--VYIWGH 245
Y L+S + + +DY G+G S G PSE + D + ++ R G +P + ++G
Sbjct: 224 SFYTGLNSRLHCNIIYDYSGYGASAGRPSEWNLYADIDAAWQALRTRYGISPDSIILYGQ 283
Query: 246 SLGTGVATNLVRRL-CERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDP 304
S+GT +L R C A++L SP T+ A FP + D
Sbjct: 284 SIGTVPTVDLASRYECA------AVVLHSPLTSGMRVA-----------FPDTKTYCFDA 326
Query: 305 ITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
F N E V I+ P+LI+H +D V+ F G LY
Sbjct: 327 -------FPNIEKVSKITSPVLIIHGMEDEVIDFSHGLALY 360
>gi|239746656 PREDICTED: hypothetical protein LOC729495 [Homo
sapiens]
Length = 403
Score = 63.2 bits (152), Expect = 4e-10
Identities = 64/221 (28%), Positives = 95/221 (42%), Gaps = 37/221 (16%)
Query: 129 YLQPEEDVTIGVWHTVPAVWWKNAQG-KDQMWYEDALASSHPIILYLHGNAGTRGGDHRV 187
Y Q E D TI V+ T K+A G + Y + + + + HGNA G
Sbjct: 173 YSQRELD-TIEVFPT------KSAHGNRVSCMYVRCVPGARYTVFFSHGNAVDLG--QMS 223
Query: 188 ELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNP--VYIWGH 245
Y L+S + + +DY G+G S G PSE + D + ++ R G +P + ++G
Sbjct: 224 SFYTGLNSRLHCNIIYDYSGYGASAGRPSEWNLYADIDAAWQALRTRYGISPDSIILYGQ 283
Query: 246 SLGTGVATNLVRRL-CERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDP 304
S+GT +L R C A++L SP T+ A FP + D
Sbjct: 284 SIGTVPTVDLASRYECA------AVVLHSPLTSGMRVA-----------FPDTKTYCFDA 326
Query: 305 ITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
F N E V I+ P+LI+H +D V+ F G LY
Sbjct: 327 -------FPNIEKVSKITSPVLIIHGMEDEVIDFSHGLALY 360
>gi|194306564 hypothetical protein LOC81926 isoform 2 [Homo sapiens]
Length = 310
Score = 62.8 bits (151), Expect = 5e-10
Identities = 67/222 (30%), Positives = 98/222 (44%), Gaps = 37/222 (16%)
Query: 129 YLQPEEDVTIGVWHTVPAVWWKNAQG-KDQMWYEDALASSHPIILYLHGNAGTRGGDHRV 187
Y Q E D TI V+ T K+A+G + Y + + +L+ HGNA G
Sbjct: 78 YSQRELD-TIEVFPT------KSARGNRVSCMYVRCVPGARYTVLFSHGNAVDLG--QMS 128
Query: 188 ELYKVLSS-LGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNP--VYIWG 244
Y L S L ++ ++DY G+G S G PSER + D + ++ R G +P + ++G
Sbjct: 129 SFYIGLGSRLHCNIFSYDYSGYGASSGRPSERNLYADIDAAWQALRTRYGISPDSIILYG 188
Query: 245 HSLGTGVATNLVRRL-CERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLD 303
S+GT +L R C A++L SP T+ A FP
Sbjct: 189 QSIGTVPTVDLASRYECA------AVVLHSPLTSGMRVA-----------FPD------T 225
Query: 304 PITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
T F N E V I+ P+LI+H +D V+ F G LY
Sbjct: 226 KKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALY 267
>gi|194306562 hypothetical protein LOC81926 isoform 1 [Homo sapiens]
Length = 361
Score = 61.2 bits (147), Expect = 2e-09
Identities = 55/179 (30%), Positives = 80/179 (44%), Gaps = 29/179 (16%)
Query: 171 ILYLHGNAGTRGGDHRVELYKVLSS-LGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFD 229
+L+ HGNA G Y L S L ++ ++DY G+G S G PSER + D +
Sbjct: 165 VLFSHGNAVDLG--QMSSFYIGLGSRLHCNIFSYDYSGYGASSGRPSERNLYADIDAAWQ 222
Query: 230 WIKARSGDNP--VYIWGHSLGTGVATNLVRRL-CERETPPDALILESPFTNIREEAKSHP 286
++ R G +P + ++G S+GT +L R C A++L SP T+ A
Sbjct: 223 ALRTRYGISPDSIILYGQSIGTVPTVDLASRYECA------AVVLHSPLTSGMRVA---- 272
Query: 287 FSVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
FP T F N E V I+ P+LI+H +D V+ F G LY
Sbjct: 273 -------FPD------TKKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALY 318
>gi|239753043 PREDICTED: hypothetical protein [Homo sapiens]
Length = 451
Score = 59.7 bits (143), Expect = 5e-09
Identities = 64/221 (28%), Positives = 94/221 (42%), Gaps = 35/221 (15%)
Query: 129 YLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGTRGGDHRVE 188
Y Q E D TI V+ T A + + Y + + +L+ H NA G
Sbjct: 151 YSQRELD-TIEVFPTKSA-----RRNRVSCMYVRCVTGARYTVLFSHSNAVDLG--QMSS 202
Query: 189 LYKVLSS-LGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNP--VYIWGH 245
Y L S L ++ ++DY G+G S G PSER + D + ++ R G +P + ++G
Sbjct: 203 FYIGLGSRLHCNIFSYDYSGYGASSGRPSERNLYADIDAAWQALRTRYGISPDSIILYGQ 262
Query: 246 SLGTGVATNLVRRL-CERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDP 304
S+GT +L R C A++L SP T+ A FP
Sbjct: 263 SIGTVPTVDLASRYECA------AVVLHSPLTSGMRVA-----------FPD------TK 299
Query: 305 ITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
T F N E V I+ P+LI+H +D V+ F G LY
Sbjct: 300 KTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALY 340
>gi|151301175 hypothetical protein LOC58489 [Homo sapiens]
Length = 329
Score = 56.6 bits (135), Expect = 4e-08
Identities = 48/185 (25%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 166 SSHPIILYLHGNAGTRGGDHRVELYKVLSS-LGYHVVTFDYRGWGDSVGTPSERGMTYDA 224
SS +L+ HGNA G Y L S + ++ ++DY G+G S G PSE+ + D
Sbjct: 130 SSRYTLLFSHGNAVDLG--QMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADI 187
Query: 225 LHVFDWIKARSGDNP--VYIWGHSLGTGVATNLVRRL-CERETPPDALILESP-FTNIRE 280
+ ++ R G +P + ++G S+GT +L R C A+IL SP + +R
Sbjct: 188 DAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECA------AVILHSPLMSGLRV 241
Query: 281 EAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQL 340
+ + FP D + ++ P+L++H +D V+ F
Sbjct: 242 AFPDTRKTYCFDAFPSID------------------KISKVTSPVLVIHGTEDEVIDFSH 283
Query: 341 GRKLY 345
G +Y
Sbjct: 284 GLAMY 288
>gi|71051602 family with sequence similarity 108, member B1 isoform
2 [Homo sapiens]
Length = 288
Score = 56.2 bits (134), Expect = 5e-08
Identities = 51/178 (28%), Positives = 79/178 (44%), Gaps = 27/178 (15%)
Query: 171 ILYLHGNAGTRGGDHRVELYKVLSS-LGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFD 229
+L+ HGNA G Y L S + ++ ++DY G+G S G P+E+ + D +
Sbjct: 94 LLFSHGNAVDLG--QMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADIEAAWL 151
Query: 230 WIKARSGDNP--VYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPF 287
++ R G P V I+G S+GT + +L R A+IL SP T+ A
Sbjct: 152 ALRTRYGIRPENVIIYGQSIGTVPSVDLAARY-----ESAAVILHSPLTSGMRVA----- 201
Query: 288 SVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
FP T F N + + I+ P+LI+H +D V+ F G L+
Sbjct: 202 ------FPD------TKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALF 247
>gi|71051600 family with sequence similarity 108, member B1 isoform
1 [Homo sapiens]
Length = 293
Score = 56.2 bits (134), Expect = 5e-08
Identities = 51/178 (28%), Positives = 79/178 (44%), Gaps = 27/178 (15%)
Query: 171 ILYLHGNAGTRGGDHRVELYKVLSS-LGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFD 229
+L+ HGNA G Y L S + ++ ++DY G+G S G P+E+ + D +
Sbjct: 94 LLFSHGNAVDLG--QMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADIEAAWL 151
Query: 230 WIKARSGDNP--VYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPF 287
++ R G P V I+G S+GT + +L R A+IL SP T+ A
Sbjct: 152 ALRTRYGIRPENVIIYGQSIGTVPSVDLAARY-----ESAAVILHSPLTSGMRVA----- 201
Query: 288 SVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLY 345
FP T F N + + I+ P+LI+H +D V+ F G L+
Sbjct: 202 ------FPD------TKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALF 247
>gi|8923001 abhydrolase domain containing 10 [Homo sapiens]
Length = 306
Score = 39.3 bits (90), Expect = 0.006
Identities = 45/190 (23%), Positives = 74/190 (38%), Gaps = 21/190 (11%)
Query: 164 LASSHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGM--- 220
L P I+++ G G + + + SLG+ + FDY G G S G E +
Sbjct: 71 LKGKSPGIIFIPGYLSYMNGTKALAIEEFCKSLGHACIRFDYSGVGSSDGNSEESTLGKW 130
Query: 221 TYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNL-------VRRLCERETPPDALILES 273
D L + D + D P + G SLG + + V L T D L+ +
Sbjct: 131 RKDVLSIIDDL----ADGPQILVGSSLGGWLMLHAAIARPEKVVALIGVATAADTLV--T 184
Query: 274 PFTNIREEAKSH-PFSVIYRYFPGFDWFFLDPITSSGIKFANDENVKH----ISCPLLIL 328
F + E K ++ + + + S IK A + H ++CP+ +L
Sbjct: 185 KFNQLPVELKKEVEMKGVWSMPSKYSEEGVYNVQYSFIKEAEHHCLLHSPIPVNCPIRLL 244
Query: 329 HAEDDPVVPF 338
H D +VP+
Sbjct: 245 HGMKDDIVPW 254
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 33.9 bits (76), Expect = 0.27
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 145 PAVWWKNAQGKDQMW-YEDALASSHPIILYLHGNAGTRGGD 184
PA+WW N +GK+ MW + + +S L G G + GD
Sbjct: 67 PALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGD 107
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 33.9 bits (76), Expect = 0.27
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 145 PAVWWKNAQGKDQMW-YEDALASSHPIILYLHGNAGTRGGD 184
PA+WW N +GK+ MW + + +S L G G + GD
Sbjct: 67 PALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGD 107
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 33.9 bits (76), Expect = 0.27
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 145 PAVWWKNAQGKDQMW-YEDALASSHPIILYLHGNAGTRGGD 184
PA+WW N +GK+ MW + + +S L G G + GD
Sbjct: 67 PALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGD 107
>gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]
Length = 613
Score = 33.9 bits (76), Expect = 0.27
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 9/70 (12%)
Query: 109 PYFIDLKKPQDQGLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSH 168
P ++L P+ L + L PE++ GV+H P+ W ++A D WY+ A S
Sbjct: 516 PVSVELVGPRSHRLRL---HSLGPEDE---GVYHCAPSAWVQHA---DYSWYQAGSARSG 566
Query: 169 PIILYLHGNA 178
P+ +Y + +A
Sbjct: 567 PVTVYPYMHA 576
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 33.9 bits (76), Expect = 0.27
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 145 PAVWWKNAQGKDQMW-YEDALASSHPIILYLHGNAGTRGGD 184
PA+WW N +GK+ MW + + +S L G G + GD
Sbjct: 67 PALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGD 107
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 33.9 bits (76), Expect = 0.27
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 145 PAVWWKNAQGKDQMW-YEDALASSHPIILYLHGNAGTRGGD 184
PA+WW N +GK+ MW + + +S L G G + GD
Sbjct: 67 PALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGD 107
>gi|221316588 biphenyl hydrolase-like [Homo sapiens]
Length = 291
Score = 33.1 bits (74), Expect = 0.45
Identities = 54/213 (25%), Positives = 83/213 (38%), Gaps = 46/213 (21%)
Query: 157 QMWYEDALASSHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPS 216
Q+ Y+ H ++L L G G+ D +L K L+ + VV +D RG+G S P
Sbjct: 50 QLHYQQTGEGDHAVLL-LPGMLGSGETDFGPQL-KNLNKKLFTVVAWDPRGYGHS--RPP 105
Query: 217 ERGMTYD-----ALHVFDWIKA-----------RSGDNPVYIWGHSLGTGVATNLVRRLC 260
+R D A D +KA G I + + ++
Sbjct: 106 DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGAN 165
Query: 261 ERETPPDALILESPFTNIREEAK-----SHPFSVIYRYFPGFDWF------FLDPITSSG 309
T D++I E IR+ +K P +Y G+D+F ++D I
Sbjct: 166 AYVTDEDSMIYEG----IRDVSKWSERTRKPLEALY----GYDYFARTCEKWVDGIRQ-- 215
Query: 310 IKFANDENV-----KHISCPLLILHAEDDPVVP 337
K D N+ + CP LI+H E DP+VP
Sbjct: 216 FKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP 248
>gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens]
Length = 303
Score = 32.0 bits (71), Expect = 1.0
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 16/120 (13%)
Query: 171 ILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVF-- 228
++++ AG G + EL ++L L V D+ G G S G ER + D HVF
Sbjct: 44 LIFVSHGAGEHSGRYE-ELARMLMGLDLLVFAHDHVGHGQSEG---ERMVVSD-FHVFVR 98
Query: 229 ------DWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEA 282
D ++ PV++ GHS+G +A + ER ++L SP E+
Sbjct: 99 DVLQHVDSMQKDYPGLPVFLLGHSMGGAIA---ILTAAERPGHFAGMVLISPLVLANPES 155
>gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens]
Length = 313
Score = 32.0 bits (71), Expect = 1.0
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 16/120 (13%)
Query: 171 ILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVF-- 228
++++ AG G + EL ++L L V D+ G G S G ER + D HVF
Sbjct: 54 LIFVSHGAGEHSGRYE-ELARMLMGLDLLVFAHDHVGHGQSEG---ERMVVSD-FHVFVR 108
Query: 229 ------DWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEA 282
D ++ PV++ GHS+G +A + ER ++L SP E+
Sbjct: 109 DVLQHVDSMQKDYPGLPVFLLGHSMGGAIA---ILTAAERPGHFAGMVLISPLVLANPES 165
>gi|23397663 alpha/beta hydrolase domain containing protein 3 [Homo
sapiens]
Length = 409
Score = 32.0 bits (71), Expect = 1.0
Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 165 ASSHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRG-WGDSVGTP 215
AS+ P IL L G GT + + + + LGY V F+ RG G+++ TP
Sbjct: 136 ASTRPTILLLPGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGENLLTP 187
>gi|26051273 voltage-gated potassium channel, subfamily H, member 2
isoform c [Homo sapiens]
Length = 819
Score = 29.6 bits (65), Expect = 5.0
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 267 DALI-LESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITS 307
D LI + + N EE SHP + YF G WF +D + +
Sbjct: 126 DILINFRTTYVNANEEVVSHPGRIAVHYFKG--WFLIDMVAA 165
>gi|26051271 voltage-gated potassium channel, subfamily H, member 2
isoform b [Homo sapiens]
Length = 888
Score = 29.6 bits (65), Expect = 5.0
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 267 DALI-LESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITS 307
D LI + + N EE SHP + YF G WF +D + +
Sbjct: 466 DILINFRTTYVNANEEVVSHPGRIAVHYFKG--WFLIDMVAA 505
>gi|4557729 voltage-gated potassium channel, subfamily H, member 2
isoform a [Homo sapiens]
Length = 1159
Score = 29.6 bits (65), Expect = 5.0
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 267 DALI-LESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITS 307
D LI + + N EE SHP + YF G WF +D + +
Sbjct: 466 DILINFRTTYVNANEEVVSHPGRIAVHYFKG--WFLIDMVAA 505
>gi|218777837 abhydrolase domain containing 7 [Homo sapiens]
Length = 362
Score = 29.6 bits (65), Expect = 5.0
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 12/138 (8%)
Query: 169 PIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDAL--H 226
P++L LHG R +L + S Y VV D RG+G++ + D L
Sbjct: 94 PLMLLLHGFPEF-WYSWRYQLREFKSE--YRVVALDLRGYGETDAPIHRQNYKLDCLITD 150
Query: 227 VFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNI-REEAKSH 285
+ D + + V I GH G +A + +C E +++ P N+ E H
Sbjct: 151 IKDILDSLGYSKCVLI-GHDWGGMIAWLIA--ICYPEMVMKLIVINFPHPNVFTEYILRH 207
Query: 286 PFSVI---YRYFPGFDWF 300
P ++ Y YF WF
Sbjct: 208 PAQLLKSSYYYFFQIPWF 225
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,637,326
Number of Sequences: 37866
Number of extensions: 771181
Number of successful extensions: 1559
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1519
Number of HSP's gapped (non-prelim): 40
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.