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Search of human proteins with 14269566
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
(931 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens] 1840 0.0
gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens] 687 0.0
gi|226423889 myocardin isoform 1 [Homo sapiens] 452 e-127
gi|23957692 myocardin isoform 2 [Homo sapiens] 449 e-126
gi|226423891 myocardin isoform 3 [Homo sapiens] 324 3e-88
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 76 2e-13
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 71 5e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni... 64 7e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 64 9e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 64 9e-10
gi|195963410 MEF2 activating motif and SAP domain containing tra... 63 1e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 63 1e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 63 1e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 2e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 62 2e-09
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 62 2e-09
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 61 4e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 7e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 60 9e-09
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 60 9e-09
gi|50345997 E1A binding protein p300 [Homo sapiens] 57 6e-08
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 57 6e-08
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 57 6e-08
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 57 6e-08
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 57 6e-08
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 57 1e-07
gi|32698970 MEF2 activating motif and SAP domain containing tran... 57 1e-07
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 57 1e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is... 56 2e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 55 2e-07
>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
Length = 931
Score = 1840 bits (4765), Expect = 0.0
Identities = 931/931 (100%), Positives = 931/931 (100%)
Query: 1 MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLK 60
MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLK
Sbjct: 1 MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLK 60
Query: 61 LKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSS 120
LKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSS
Sbjct: 61 LKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSS 120
Query: 121 DALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQP 180
DALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQP
Sbjct: 121 DALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQP 180
Query: 181 PLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQ 240
PLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQ
Sbjct: 181 PLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQ 240
Query: 241 YIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEAL 300
YIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEAL
Sbjct: 241 YIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEAL 300
Query: 301 GSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELK 360
GSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELK
Sbjct: 301 GSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELK 360
Query: 361 LRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPA 420
LRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPA
Sbjct: 361 LRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPA 420
Query: 421 LVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMV 480
LVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMV
Sbjct: 421 LVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMV 480
Query: 481 TSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRM 540
TSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRM
Sbjct: 481 TSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRM 540
Query: 541 LRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPS 600
LRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPS
Sbjct: 541 LRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPS 600
Query: 601 LAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLIT 660
LAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLIT
Sbjct: 601 LAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLIT 660
Query: 661 DSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSL 720
DSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSL
Sbjct: 661 DSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSL 720
Query: 721 LKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPK 780
LKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPK
Sbjct: 721 LKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPK 780
Query: 781 TVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLI 840
TVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLI
Sbjct: 781 TVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLI 840
Query: 841 DDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMDWLELSSGGPVL 900
DDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMDWLELSSGGPVL
Sbjct: 841 DDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMDWLELSSGGPVL 900
Query: 901 SLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL 931
SLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL
Sbjct: 901 SLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL 931
>gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]
Length = 1049
Score = 687 bits (1772), Expect = 0.0
Identities = 453/1016 (44%), Positives = 590/1016 (58%), Gaps = 126/1016 (12%)
Query: 1 MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLK 60
MPPLKSPAAFHEQ +SLERARTE++LK KIRSRP+RSELVRMHILEET AEPSLQA Q+K
Sbjct: 72 MPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMK 131
Query: 61 LKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAII-VGQVNYPKVADSSSFDEDS 119
LKRARLADDLNEKIAQRPGPMELVEKNILPV+SS+KEAII VG+ +YP SFDEDS
Sbjct: 132 LKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVGKEDYPHTQGDFSFDEDS 191
Query: 120 SDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQ 179
SDALSP+QPAS ESQGS SP E +VSE T+ +P Q S P + + A+Q
Sbjct: 192 SDALSPDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEFLKTPPTADQ 251
Query: 180 PPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYH 239
P PP P P TN T+ +AK P L+KQS PK+ ++K RSKK K+ KP+VKKLKYH
Sbjct: 252 P--PPRPAAPVLPTN--TVSSAKPGPALVKQSHPKNPNDK-HRSKKCKDPKPRVKKLKYH 306
Query: 240 QYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEA 299
QYIPPDQK ++ P MDS+YA++LQQQQLFLQLQIL+ QQ+QH+NYQ ILPAP K +
Sbjct: 307 QYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILS-QQKQHYNYQTILPAPFKPLNDK 365
Query: 300 LGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQEL 359
+SG NS+ ++ P RQN+++ KPG LP++LDD+KV+ELK EL
Sbjct: 366 NSNSG----------NSALNNATP---NTPRQNTSTPVRKPGPLPSSLDDLKVSELKTEL 412
Query: 360 KLRSLPVSGTKTELIERLRAYQDQISP--VPGAPKAPAATSILHKAGEVVVAFPAARLST 417
KLR LPVSGTK +LIERL+ YQ+ S G A ++++I+ EV VA P L
Sbjct: 413 KLRGLPVSGTKPDLIERLKPYQEVNSSGLAAGGIVAVSSSAIVTSNPEVTVALPVTTLHN 472
Query: 418 GPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFG 477
V + ++ + + +S + + S P+SP+PSE+S LST D N DTF
Sbjct: 473 ---TVTSSVSTLKAELPPTGTSNATRVENVHSPLPISPSPSEQSSLSTDDTNM--ADTFT 527
Query: 478 EMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEAL 537
E++T L +SPL++ E+ S LS EL+ +KD+ LQEK+KQIE L
Sbjct: 528 EIMTMMSPSQFLSSSPLRMTNNEDSLSPTSSTLS---NLELDAAEKDRKLQEKEKQIEEL 584
Query: 538 TRMLRQKQQLVERLKLQLEQEKRAQQPAPAPA----------------PLGTPVKQENSF 581
R L Q+Q+LVE LK+QLE EKR QQ P A LG+ +K E S
Sbjct: 585 KRKLEQEQKLVEVLKMQLEVEKRGQQQRPLEAQPSAPGHSVKSDQKHGSLGSSIKDEASL 644
Query: 582 SSCQLSQQPLGPA-----HPFNPS----LAAPATNHIDPCAVAPGPPSVVVKQEALQPEP 632
C S+QP+ A P + +A A V VV Q P+
Sbjct: 645 PDCSSSRQPIPVASHAVGQPVSTGGQTLVAKKAVVIKQEVPVGQAEQQSVVSQFYTSPQA 704
Query: 633 EPVPAPQLLLGPQGP--SLIKGVAPPT--------------------LITDSTGTHLVL- 669
PQ+ Q P +L G+AP + T+S ++ VL
Sbjct: 705 GMQTQPQIATAAQIPTAALASGLAPTVPQTQDTFPQHVLSQPQQVRKVFTNSASSNTVLP 764
Query: 670 --------------------TVTNKNADSPGLSSG--SPQQPSSQPGSPAPAPSAQMDLE 707
+ ++NA P L +G +P +PSS P P Q ++
Sbjct: 765 YQRHPAPAVQQPFINKASNSVLQSRNAPLPSLQNGPNTPNKPSS------PPPPQQFVVQ 818
Query: 708 HPLQPLFGTPTSLLKKEPPGYEEAM-----SQQPKQQENGSSSQQMDDLFDILIQSGEIS 762
H LFG+P + K+PP YEEA+ +Q P + + + SQQMDDLFDILI+SGEIS
Sbjct: 819 H---SLFGSPVA-KTKDPPRYEEAIKQTRSTQAPLPEISNAHSQQMDDLFDILIKSGEIS 874
Query: 763 ADFKEPPSLPGKEKPSPKTVCGSP---LAAQPSPSAEL-PQAAPPPPG--SPSLPGRLED 816
KE PS K +P ++ P + ++P P ++ P + P G S SL +LE
Sbjct: 875 LPIKEEPSPISKMRPVTASITTMPVNTVVSRPPPQVQMAPPVSLEPMGSLSASLENQLEA 934
Query: 817 FLE----SSTGLPLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEP 872
FL+ S+ +P L S + EP SLI+DL + +LS + +LDH SPM+TSE F
Sbjct: 935 FLDGTLPSANEIPPLQSSSEDREPFSLIEDLQNDLLSHSGMLDHSHSPMETSETQFA-AG 993
Query: 873 SSTMGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDFLDGHDLQLHWD 928
+ + LDL+D +LD+M+WL+++ L PLSTTAPS+FS DFLD DL L WD
Sbjct: 994 TPCLSLDLSDSNLDNMEWLDITMPNSSSGLTPLSTTAPSMFSADFLDPQDLPLPWD 1049
>gi|226423889 myocardin isoform 1 [Homo sapiens]
Length = 986
Score = 452 bits (1162), Expect = e-127
Identities = 365/1008 (36%), Positives = 505/1008 (50%), Gaps = 152/1008 (15%)
Query: 1 MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLK 60
+PPLK PA FHEQR+ L+ + ++ LKRK R+R ++LV MHIL+ ++AE S+ Q+K
Sbjct: 39 IPPLKRPAEFHEQRKHLDSDKAKNSLKRKARNRCNSADLVNMHILQASTAERSIPTAQMK 98
Query: 61 LKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDED-S 119
LKRARLADDLNEKIA RPGP+ELVEKNILPV+S++KEAI QV++ K D+ +F+ED S
Sbjct: 99 LKRARLADDLNEKIALRPGPLELVEKNILPVDSAVKEAIKGNQVSFSKSTDAFAFEEDSS 158
Query: 120 SDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGR-DSREMLFLAE 178
SD LSP+Q S + Q S SP +A+ S+ + + + + S R DS +
Sbjct: 159 SDGLSPDQTRSEDPQNSAGSPPDAKASDTPSTGSLGTNQDLASGSENDRNDSASQ--PSH 216
Query: 179 QPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQS-QPKSASEKSQRSKKAKELKPKVKKLK 237
Q L PP STP + + + KS + R KK K+ KPKVKKLK
Sbjct: 217 QSDAGKQGLGPP------------STPIAVHAAVKSKSLGDSKNRHKKPKDPKPKVKKLK 264
Query: 238 YHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHN-------YQAILP 290
YHQYIPPDQK ++ PPMDS+YA++LQQQQLFLQLQIL+QQQQQ + +QA L
Sbjct: 265 YHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQQHRFSYLGMHQAQLK 324
Query: 291 APPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDM 350
P + SS TP + + +S SG G KPG LP NLDD+
Sbjct: 325 EPNEQMVRNPNSSSTPLSNTPLSPVKNSFSGQTGVSSF----------KPGPLPPNLDDL 374
Query: 351 KVAELKQELKLRSLPVSGTKTELIERLRAYQD-QISPVPGAPKAPAATSILHKAGEV-VV 408
KV+EL+Q+L++R LPVSGTKT L++RLR +QD +PVP G++ V
Sbjct: 375 KVSELRQQLRIRGLPVSGTKTALMDRLRPFQDCSGNPVP-------------NFGDITTV 421
Query: 409 AFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDE 468
FP +T P ++ A S+G FGST S+PP+SP S+ S+
Sbjct: 422 TFPVTP-NTLPNYQSSSSTSA-------LSNGFYHFGSTSSSPPISPASSDLSV-----A 468
Query: 469 NSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRD--KDQM 526
S P DTF + SP L SP+ + +E S +EL+G D KD+M
Sbjct: 469 GSLP-DTFND--ASP--SFGLHPSPVHVCTEES---LMSSLNGGSVPSELDGLDSEKDKM 520
Query: 527 LQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAP-LGTPVKQENSFSSCQ 585
L EK K I LT L+Q+Q+ VE L++QL+++KR P P L +KQE + SSC
Sbjct: 521 LVEKQKVINELTWKLQQEQRQVEELRMQLQKQKRNNCSEKKPLPFLAASIKQEEAVSSCP 580
Query: 586 L-SQQPL------GPAHPFNPSLAAPATNHI-DPCAVAPGPPSVVVKQEALQPEPEPVPA 637
SQ P+ HP P+ A + + V + V+ L P+ P +
Sbjct: 581 FASQVPVKRQSSSSECHP--PACEAAQLQPLGNAHCVESSDQTNVLSSTFLSPQCSPQHS 638
Query: 638 P-QLLLGPQGPSLIKGVAPPTLITDSTG------------THLVLTVTNKNADSPGLSSG 684
P + PQ SL P + S+G + V T N A S
Sbjct: 639 PLGAVKSPQHISLPPSPNNPHFLPSSSGAQGEGHRVSSPISSQVCTAQNSGAHDGHPPSF 698
Query: 685 SPQQPSSQP--------------GSPAP-APSAQMDL-----EHPLQPLFGTPTSLLKK- 723
SP S P G+P P +P Q + + P F P+ K
Sbjct: 699 SPHSSSLHPPFSGAQADSSHGAGGNPCPKSPCVQQKMAGLHSSDKVGPKFSIPSPTFSKS 758
Query: 724 --------EPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKE 775
+PP YE+A+ QQ + SQQMD+L D+LI+SGE+ AD +E S K
Sbjct: 759 SSAISEVTQPPSYEDAVKQQM------TRSQQMDELLDVLIESGEMPADAREDHSCLQKV 812
Query: 776 KPSPKTVCGSPLAAQPSPSAELPQAA-----PPPPGSPSLPGRLEDFLESSTGL------ 824
P++ SP A PSA QA+ P P + LE L S + L
Sbjct: 813 PKIPRS-SRSPTAVLTKPSASFEQASSGSQIPFDPYATDSDEHLEVLLNSQSPLGKMSDV 871
Query: 825 PLLTSGHDGPEPLSLIDDLHSQ----MLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDL 880
LL G + P ++D + + ++ IL P SPM T F P + GL L
Sbjct: 872 TLLKIGSEEPHFDGIMDGFSGKAAEDLFNAHEILPGPLSPMQT---QFSPSSVDSNGLQL 928
Query: 881 A--DGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDFLDGHDLQLH 926
+ + ++M+WL+L+ + L+T++PS+F+ DFLD DL L+
Sbjct: 929 SFTESPWETMEWLDLTPPNSTPGFSALTTSSPSIFNIDFLDVTDLNLN 976
>gi|23957692 myocardin isoform 2 [Homo sapiens]
Length = 938
Score = 449 bits (1156), Expect = e-126
Identities = 356/969 (36%), Positives = 495/969 (51%), Gaps = 122/969 (12%)
Query: 1 MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLK 60
+PPLK PA FHEQR+ L+ + ++ LKRK R+R ++LV MHIL+ ++AE S+ Q+K
Sbjct: 39 IPPLKRPAEFHEQRKHLDSDKAKNSLKRKARNRCNSADLVNMHILQASTAERSIPTAQMK 98
Query: 61 LKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDED-S 119
LKRARLADDLNEKIA RPGP+ELVEKNILPV+S++KEAI QV++ K D+ +F+ED S
Sbjct: 99 LKRARLADDLNEKIALRPGPLELVEKNILPVDSAVKEAIKGNQVSFSKSTDAFAFEEDSS 158
Query: 120 SDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGR-DSREMLFLAE 178
SD LSP+Q S + Q S SP +A+ S+ + + + + S R DS +
Sbjct: 159 SDGLSPDQTRSEDPQNSAGSPPDAKASDTPSTGSLGTNQDLASGSENDRNDSASQ--PSH 216
Query: 179 QPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQS-QPKSASEKSQRSKKAKELKPKVKKLK 237
Q L PP STP + + + KS + R KK K+ KPKVKKLK
Sbjct: 217 QSDAGKQGLGPP------------STPIAVHAAVKSKSLGDSKNRHKKPKDPKPKVKKLK 264
Query: 238 YHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHN-------YQAILP 290
YHQYIPPDQK ++ PPMDS+YA++LQQQQLFLQLQIL+QQQQQ + +QA L
Sbjct: 265 YHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQQHRFSYLGMHQAQLK 324
Query: 291 APPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDM 350
P + SS TP + + +S SG G KPG LP NLDD+
Sbjct: 325 EPNEQMVRNPNSSSTPLSNTPLSPVKNSFSGQTGVSSF----------KPGPLPPNLDDL 374
Query: 351 KVAELKQELKLRSLPVSGTKTELIERLRAYQD-QISPVPGAPKAPAATSILHKAGEV-VV 408
KV+EL+Q+L++R LPVSGTKT L++RLR +QD +PVP G++ V
Sbjct: 375 KVSELRQQLRIRGLPVSGTKTALMDRLRPFQDCSGNPVP-------------NFGDITTV 421
Query: 409 AFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDE 468
FP +T P ++ A S+G FGST S+PP+SP S+ S+
Sbjct: 422 TFPVTP-NTLPNYQSSSSTSA-------LSNGFYHFGSTSSSPPISPASSDLSV-----A 468
Query: 469 NSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRD--KDQM 526
S P DTF + SP L SP+ + +E S +EL+G D KD+M
Sbjct: 469 GSLP-DTFND--ASP--SFGLHPSPVHVCTEES---LMSSLNGGSVPSELDGLDSEKDKM 520
Query: 527 LQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAP-LGTPVKQENSFSSCQ 585
L EK K I LT L+Q+Q+ VE L++QL+++KR P P L +KQE + SSC
Sbjct: 521 LVEKQKVINELTWKLQQEQRQVEELRMQLQKQKRNNCSEKKPLPFLAASIKQEEAVSSCP 580
Query: 586 L-SQQPL------GPAHPFNPSLAAPATNHI-DPCAVAPGPPSVVVKQEALQPEPEPVPA 637
SQ P+ HP P+ A + + V + V+ L P+ P +
Sbjct: 581 FASQVPVKRQSSSSECHP--PACEAAQLQPLGNAHCVESSDQTNVLSSTFLSPQCSPQHS 638
Query: 638 P-QLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSP 696
P + PQ SL P + S+G SP S Q + S
Sbjct: 639 PLGAVKSPQHISLPPSPNNPHFLPSSSGAQ----GEGHRVSSPISSQVCTAQMAGLHSSD 694
Query: 697 APAPSAQMDLEHPLQPLFGTPTSLLKK--EPPGYEEAMSQQPKQQENGSSSQQMDDLFDI 754
P + P F +S + + +PP YE+A+ QQ + SQQMD+L D+
Sbjct: 695 KVGPKFSIP-----SPTFSKSSSAISEVTQPPSYEDAVKQQM------TRSQQMDELLDV 743
Query: 755 LIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAA-----PPPPGSPS 809
LI+SGE+ AD +E S K P++ SP A PSA QA+ P P +
Sbjct: 744 LIESGEMPADAREDHSCLQKVPKIPRS-SRSPTAVLTKPSASFEQASSGSQIPFDPYATD 802
Query: 810 LPGRLEDFLESSTGL------PLLTSGHDGPEPLSLIDDLHSQ----MLSSTAILDHPPS 859
LE L S + L LL G + P ++D + + ++ IL P S
Sbjct: 803 SDEHLEVLLNSQSPLGKMSDVTLLKIGSEEPHFDGIMDGFSGKAAEDLFNAHEILPGPLS 862
Query: 860 PMDTSELHFVPEPSSTMGLDLA--DGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDF 917
PM T F P + GL L+ + ++M+WL+L+ + L+T++PS+F+ DF
Sbjct: 863 PMQT---QFSPSSVDSNGLQLSFTESPWETMEWLDLTPPNSTPGFSALTTSSPSIFNIDF 919
Query: 918 LDGHDLQLH 926
LD DL L+
Sbjct: 920 LDVTDLNLN 928
>gi|226423891 myocardin isoform 3 [Homo sapiens]
Length = 684
Score = 324 bits (830), Expect = 3e-88
Identities = 268/740 (36%), Positives = 363/740 (49%), Gaps = 123/740 (16%)
Query: 59 LKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDED 118
+KLKRARLADDLNEKIA RPGP+ELVEKNILPV+S++KEAI QV++ K D+ +F+ED
Sbjct: 1 MKLKRARLADDLNEKIALRPGPLELVEKNILPVDSAVKEAIKGNQVSFSKSTDAFAFEED 60
Query: 119 SS-DALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLA 177
SS D LSP+Q S + Q S SP +A+ S+ + + + + S R+ +
Sbjct: 61 SSSDGLSPDQTRSEDPQNSAGSPPDAKASDTPSTGSLGTNQDLASGSENDRNDSASQ-PS 119
Query: 178 EQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQS-QPKSASEKSQRSKKAKELKPKVKKL 236
Q L PPS TP + + + KS + R KK K+ KPKVKKL
Sbjct: 120 HQSDAGKQGLGPPS------------TPIAVHAAVKSKSLGDSKNRHKKPKDPKPKVKKL 167
Query: 237 KYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHN-------YQAIL 289
KYHQYIPPDQK ++ PPMDS+YA++LQQQQLFLQLQIL+QQQQQ + +QA L
Sbjct: 168 KYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQQHRFSYLGMHQAQL 227
Query: 290 PAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDD 349
P + SS TP + + +S SG G KPG LP NLDD
Sbjct: 228 KEPNEQMVRNPNSSSTPLSNTPLSPVKNSFSGQTGVSSF----------KPGPLPPNLDD 277
Query: 350 MKVAELKQELKLRSLPVSGTKTELIERLRAYQD-QISPVPGAPKAPAATSILHKAGEV-V 407
+KV+EL+Q+L++R LPVSGTKT L++RLR +QD +PVP G++
Sbjct: 278 LKVSELRQQLRIRGLPVSGTKTALMDRLRPFQDCSGNPVP-------------NFGDITT 324
Query: 408 VAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGD 467
V FP +T P ++ A S+G FGST S+PP+SP S+ S+
Sbjct: 325 VTFPVTP-NTLPNYQSSSSTSA-------LSNGFYHFGSTSSSPPISPASSDLSV----- 371
Query: 468 ENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRD--KDQ 525
S P DTF + SP L SP+ + +E S +EL+G D KD+
Sbjct: 372 AGSLP-DTFND--ASP--SFGLHPSPVHVCTEES---LMSSLNGGSVPSELDGLDSEKDK 423
Query: 526 MLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAP-LGTPVKQENSFSSC 584
ML EK K I LT L+Q+Q+ VE L++QL+++KR P P L +KQE + SSC
Sbjct: 424 MLVEKQKVINELTWKLQQEQRQVEELRMQLQKQKRNNCSEKKPLPFLAASIKQEEAVSSC 483
Query: 585 QL-SQQPL------GPAHPFNPSLAAPATNHI-DPCAVAPGPPSVVVKQEALQPEPEPVP 636
SQ P+ HP P+ A + + V + V+ L P+ P
Sbjct: 484 PFASQVPVKRQSSSSECHP--PACEAAQLQPLGNAHCVESSDQTNVLSSTFLSPQCSPQH 541
Query: 637 AP-QLLLGPQGPSLIKGVAPPTLITDSTG------------THLVLTVTNKNADSPGLSS 683
+P + PQ SL P + S+G + V T N A S
Sbjct: 542 SPLGAVKSPQHISLPPSPNNPHFLPSSSGAQGEGHRVSSPISSQVCTAQNSGAHDGHPPS 601
Query: 684 GSPQQPSSQP--------------GSPAP-APSAQMDL-----EHPLQPLFGTPTSLLKK 723
SP S P G+P P +P Q + + P F P+ K
Sbjct: 602 FSPHSSSLHPPFSGAQADSSHGAGGNPCPKSPCVQQKMAGLHSSDKVGPKFSIPSPTFSK 661
Query: 724 ---------EPPGYEEAMSQ 734
+PP YE+A+ Q
Sbjct: 662 SSSAISEVTQPPSYEDAVKQ 681
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 75.9 bits (185), Expect = 2e-13
Identities = 190/792 (23%), Positives = 259/792 (32%), Gaps = 186/792 (23%)
Query: 125 PEQPASHESQGSVPSPLEA--RVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPP- 181
P QP Q P + + + P L S+SP S P G +R + PP
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS--PSGTKARPV-----PPPD 321
Query: 182 ---LPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKY 238
P P LPPS T +P A +P+ P ++ L
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSA----------------------PPSLQTLPS 359
Query: 239 HQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPK---- 294
PP Q APP ++ Q LQ + Q H L APP
Sbjct: 360 PPATPPSQ-----APPSMTT-----PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
Query: 295 SAGEALGSSGTPPVRS------LSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLD 348
S+ +A S G+P +++ +S + +S +P +S L P +LPA+
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA-PLSLPAS-- 466
Query: 349 DMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVV- 407
L+ L P+S T I L+A S P AP + L +
Sbjct: 467 ----PPLQTSLSPAVSPLSSPLT--IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
Query: 408 --VAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLST 465
+ P A L+T P LAP + A+ + T P P + S L+T
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT--TPHLETPPCPAPCPLQAPPSPLTT 578
Query: 466 GDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQ 525
P +T + T P P+A SP L+G
Sbjct: 579 -----PPPETPSSIATPP-------------------PQAPPALASP----PLQGLPSPP 610
Query: 526 MLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQ 585
L+ + Q L L Q + +P +PL TP Q + +
Sbjct: 611 -----------LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 586 LSQQPLGP--AHPFNPSLAAPATNHIDPCAVAPG--PPSVVVKQEALQPEPEPVP--APQ 639
L Q P P + P + PA+ + P A P PPS+ + P P P +P
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719
Query: 640 LLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPA 699
PQ P + APP + P + P PS+ P P
Sbjct: 720 ATPPPQAPPPL--AAPPLQVP------------------PSPPASPPMSPSATPPPRVPP 759
Query: 700 PSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSG 759
A L+ P P P S L K PP A++ P Q
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ--------------------- 798
Query: 760 EISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQ---AAPPPPGSPSLPGRLED 816
A P S PG+ A SPSA LP A PPP P L L
Sbjct: 799 ---ALPSPPASFPGQ--------------APFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 817 FLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTM 876
S P L + P P D S + A+ PP P S PSST+
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGP--DTSVSGPRLTLALAPGPPPPPSRS-------PSSTL 892
Query: 877 -GLDLADGHLDS 887
G DLA GH S
Sbjct: 893 SGPDLA-GHSSS 903
Score = 65.5 bits (158), Expect = 2e-10
Identities = 172/704 (24%), Positives = 232/704 (32%), Gaps = 124/704 (17%)
Query: 279 QQQHHNYQAILPA----PPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNST 334
Q + QA+ P P K A ALG + P L+T + S + P P
Sbjct: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP---LATPSPSGTKARPVP-----PPDN 322
Query: 335 SLTGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAP 394
+ T P LP + L L L P S + ++ L + +P AP P
Sbjct: 323 AATPLPATLPPS------PPLATPLPLA--PPSPSAPPSLQTLPS--PPATPPSQAP--P 370
Query: 395 AATSILHKAGEVVVAFPAARLS---TGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTP 451
+ T+ +A + P ++ T P+L A A + S G +T S
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430
Query: 452 PVSPTPSERSLLSTGDENSTPGDTFGEMVTSPL-TQLTLQASP-LQI-LVKEEGPRAGSC 508
+SP ++ SL S STP D+ PL L+L ASP LQ L P +
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDS------PPLQAPLSLPASPPLQTSLSPAVSPLSSPL 484
Query: 509 CLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQ--LVERLKLQLEQEKRAQQPA- 565
+ P ++AL+ + Q L + LE + P+
Sbjct: 485 TIHP---------------------LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 566 -PAPAPLGTPVKQENSFSSC----QLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPS 620
PA L TP EN S Q + PL H P AP P + PP
Sbjct: 524 QTPPASLTTP-PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE 582
Query: 621 VVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSP- 679
P+ P A L G P L PP + + A P
Sbjct: 583 TPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642
Query: 680 -GLSSGSPQQPSS-------QPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEA 731
L++ SPQ P++ P SP P+P Q P P + + PP
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 732 MSQQPKQQENGSSSQQMDDLFDILIQSGEISA--DFKEPPSLPGKEKPSPKT-------- 781
Q P +S M Q+ A + PPS P SP
Sbjct: 703 PLQVPPSPP---ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Query: 782 -VCGSPLAAQPSPSAELPQ---AAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPL 837
+ PL PSP A LP A PPP P+L LP + G P
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA------TPPLQALPSPPASFPGQAPF 813
Query: 838 SLIDDLHSQMLS----------STAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDS 887
S L L+ + +L PPSP + L P T G D
Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ-APRRPPTPGPD-------- 864
Query: 888 MDWLELSSGGP--VLSLAPLSTTAPSLFSTDFLDGHDLQLHWDS 929
S GP L+LAP PS + L G DL H S
Sbjct: 865 -----TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 903
Score = 50.1 bits (118), Expect = 1e-05
Identities = 127/576 (22%), Positives = 181/576 (31%), Gaps = 120/576 (20%)
Query: 385 SPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKF 444
SP P P PAA +L AG V P AG + + +G +
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAV---------GRKPLAERAGGIGGATIPESAPRAGPTRS 82
Query: 445 GSTGSTPPVS-PTPSERSLLSTGDEN------STPGDTFGEMVTSPLTQLTLQASPLQIL 497
T S P S P S R + +N S+PG G PL Q L+ S + +
Sbjct: 83 AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 142
Query: 498 VKEEGPRAGS-CCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVE------- 549
+ + A LS G R + G ++ A + +
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 550 ---RLKLQLEQEKRAQQPAPAP-------APLGTPVKQENSFSSCQLSQ----------Q 589
R + E +P+PA L P + S S+ LS
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 590 PLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSL 649
P PAHP P A PP V ++ P P+ + L +
Sbjct: 263 PRAPAHPSQPKPKG---------LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313
Query: 650 IKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHP 709
+ V PP D+ T L T+ SP L++ P P SP+ PS
Sbjct: 314 ARPVPPP----DNAATPLPATL----PPSPPLATPLPLAPP----SPSAPPS-------- 353
Query: 710 LQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPP 769
LQ L P + + PP +M+ P Q + + + I + S + PP
Sbjct: 354 LQTLPSPPATPPSQAPP----SMTTPPMQ-----APPSLQTIPPIQVPHSLTSPSLQAPP 404
Query: 770 SLPGKEKPSPKTVCGSPL------------------AAQPSPSAELPQAAPP-------- 803
S T GSP PS A P +PP
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464
Query: 804 --PPGSPSLPGRLEDFLESSTGLPLLT----SGHDGPEPLS--LIDDLHSQMLSSTAILD 855
PP SL + T PL + H PLS ++ L +Q + L
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 856 HPPSPMDTSELH----FVPEPSSTMGLDLADGHLDS 887
PP+ + T L P P T L HL++
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/326 (28%), Positives = 134/326 (41%), Gaps = 27/326 (8%)
Query: 591 LGPAHPF---NPSLAAPATNHIDPCA--VAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQ 645
+ P HP + SL +P + + P V+P V + + P VP+P
Sbjct: 65 VSPHHPLMSPHYSLVSPQYSPVSPHCPLVSPHYSLVSPHRPLVSPLLSGVPSPP----SD 120
Query: 646 GPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMD 705
PSL+ GV P+L +D + V + +D P L SG P PS P P+ PS D
Sbjct: 121 VPSLLSGV--PSLPSDVSSPPS--DVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSD 176
Query: 706 LEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADF 765
+ L + +P S + P S P + S + L D+ ++ +
Sbjct: 177 VPSLLSGV-PSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLP 235
Query: 766 KEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLP 825
+ PSL G PSP + S L+ PSP +++ PP PSL L D + +P
Sbjct: 236 SDVPSLSGV--PSPPSDVPSLLSGVPSPPSDIS----PPSDVPSL---LSDVPSLPSDVP 286
Query: 826 LLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHL 885
L SG P P S + L S + S + + PPS D L VP P S + +D
Sbjct: 287 SLLSGV--PSPPSDVPSLLSDVPSPPSDVPSPPS--DIPLLSGVPSPPSDVPSPPSDVPS 342
Query: 886 DSMDWLELSSGGPVLSLAPLSTTAPS 911
D LS LS PL + PS
Sbjct: 343 PPSDVPLLSGVPSPLSDVPLLSGVPS 368
Score = 57.8 bits (138), Expect = 5e-08
Identities = 74/267 (27%), Positives = 101/267 (37%), Gaps = 14/267 (5%)
Query: 612 CAVAPGPPSVVVKQEALQPEPEP-VPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLT 670
C V SVV L P P V L+ P P L+ P + H L
Sbjct: 7 CPVVSTHYSVVSPHCPLVPPHHPLVSLHHPLVSPHFP-LVSPHHPLVSLHHPVSPHFPLV 65
Query: 671 VTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEE 730
+ SP S SPQ P P +P L P +PL S + P
Sbjct: 66 SPHHPLMSPHYSLVSPQYSPVSPHCPLVSP--HYSLVSPHRPLVSPLLSGVPSPPSDVPS 123
Query: 731 AMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPS---LPGKEKPSPKTVCGSPL 787
+S P + SS D+ +L + + PPS P + PSP + S L
Sbjct: 124 LLSGVPSLPSDVSSPPS--DVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLL 181
Query: 788 AAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQM 847
+ PSP +++P P PS L D + +PLL+ D P P S + L S +
Sbjct: 182 SGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLS---DVPSPPSDVPSLPSDV 238
Query: 848 LSSTAILDHPPSPMDTSELHFVPEPSS 874
S + + PPS + S L VP P S
Sbjct: 239 PSLSGV-PSPPSDV-PSLLSGVPSPPS 263
Score = 48.1 bits (113), Expect = 4e-05
Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 23/236 (9%)
Query: 616 PGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGV-APPTLITDSTGTHLVLT-VTN 673
P PPS V + P VP+P PSL+ GV +PP+ I+ + +L+ V +
Sbjct: 225 PSPPSDVPSLPSDVPSLSGVPSPP----SDVPSLLSGVPSPPSDISPPSDVPSLLSDVPS 280
Query: 674 KNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQ--PLFG---TPTSLLKKEPPGY 728
+D P L SG P PS P + PS D+ P PL +P S + P
Sbjct: 281 LPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDV 340
Query: 729 EEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSL---PGKEKPSPKTVCGS 785
S P S L D+ + SG + + + PSL P + S ++
Sbjct: 341 PSPPSDVP------LLSGVPSPLSDVPLLSG-VPSPPSDVPSLLMSPHRLLMSHYSLVSP 393
Query: 786 PLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPE--PLSL 839
PS +++P P SPS L + +G+P L SG P P++L
Sbjct: 394 HRLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVPSPSGVPITL 449
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 63.9 bits (154), Expect = 7e-10
Identities = 167/725 (23%), Positives = 216/725 (29%), Gaps = 168/725 (23%)
Query: 136 SVPSPLEARVSEPLLSATSASPTQV----------VSQLPMGRDSREMLFLAEQPPLP-- 183
+ P+P +A P LS TS+SP + S P G + A PP P
Sbjct: 901 ATPAPKQA----PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP----AATPPSPKG 952
Query: 184 ------------PPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKP 231
PP PPS G P+ K PT + P + S K P
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
Query: 232 KVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPA 291
V PP K A P + A P
Sbjct: 1013 AV--------TPPSPKGSPAATPFPKGAS-----------------------TPPAATPP 1041
Query: 292 PPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMK 351
PK + A TP + TT +++ P P G + SL G P A K
Sbjct: 1042 SPKGSPAA-----TPLPKGAPTTPAAT---LPSPKG--GPATPSLKGAPTPPAATPPSPK 1091
Query: 352 VAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFP 411
K +P + T L P GAP PAAT K G + P
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLAT-----PPHKGAPTTPAATPPSPKGG--LATPP 1144
Query: 412 AARLSTGPALV----AAGLA---PAEVVVATVASSGVVKFGSTGSTPPVSPT------PS 458
T PA GLA P A+ K G +P +PT PS
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 459 ERSLLSTGDENSTPGDTFGEMVTSP---LTQLTLQASPLQILVKEEGPRAGSCCLSPGGR 515
+ L+T P T SP L + + +P P+ G P G
Sbjct: 1205 PKGGLATPSPKGAP-TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
Query: 516 AELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPA--PAPAPLGT 573
+ + L K A PA P+P G
Sbjct: 1264 PTPPAATPPSL-----------------------KGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 574 PVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPE 633
P + + P P +P T P AP PP+V P
Sbjct: 1301 PATSPPKGAPTPPAATPPSPK-------GSPGT---PPPKGAPTPPAVTPPSPKGTP-TL 1349
Query: 634 PVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQP 693
P P GP PS +G PP G + + K + G P P+ P
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409
Query: 694 GSPAPAPSAQMDLEHPLQPLFG-------TPTSLLKKEPPGYEEAMSQQPKQQENGSSSQ 746
SP AP+ + E P G TP S LKK P + PK
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVS-LKKAP------ATSAPK--------- 1453
Query: 747 QMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPG 806
G + K P+LP PSPK +P S S + A P P G
Sbjct: 1454 -----------GGPATPSSKGDPTLPAVTPPSPKEP-PAPKQVATSSSPKKAPATPAPMG 1501
Query: 807 SPSLP 811
+P+LP
Sbjct: 1502 APTLP 1506
Score = 63.2 bits (152), Expect = 1e-09
Identities = 166/771 (21%), Positives = 234/771 (30%), Gaps = 133/771 (17%)
Query: 129 ASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPPLPPPPLL 188
AS + PSP + + PL +PT + LP + L P PP
Sbjct: 1032 ASTPPAATPPSPKGSPAATPL---PKGAPTTPAATLPSPKGGPATPSLKGAPT--PPAAT 1086
Query: 189 PPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQ 248
PPS G P+ K P + P + K P PP K
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT--------PPSPKG 1138
Query: 249 DRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEALGSSGTPPV 308
PP + A P PK G TPP
Sbjct: 1139 GLATPPPKGAPTT------------------------PAATPPSPK------GGLATPPP 1168
Query: 309 RSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELKLRSLPVSG 368
+ TT +++ G GLA + P A P + P G
Sbjct: 1169 KGAPTTPAATPPSPKG--GLATPSPKGAPTTPAATPPS------------------PKGG 1208
Query: 369 TKTELIERLRAYQDQISPVP-GAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLA 427
T P P GAP PAAT K G +A P+ + P AA
Sbjct: 1209 LAT--------------PSPKGAPTTPAATPPSPKGG---LATPSPK--GAPTTPAATPP 1249
Query: 428 PAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQL 487
+ AT G TPP + PS + L+T P +VT P +
Sbjct: 1250 SPKGGPATPPPKGA-------PTPPAATPPSLKGGLATPPHKGAPNPA---VVTPPSPKG 1299
Query: 488 TLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQL 547
SP + S SPG + K L +
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 548 VERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAH-PFNPSLAAPAT 606
+ A P+ P TP + + P PA P +P APAT
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK-KAPAT 1418
Query: 607 NHIDPCAVAPG-----PPSVV---VKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTL 658
A P PP+V +K+ P+ PA +G + V PP+
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP---SSKGDPTLPAVTPPSP 1475
Query: 659 ITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLF---- 714
+ + + K A + G+P P+ P SP P+ P+ P
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 715 -GTPTSLLKKE---PPGYEEAMSQQ------PKQQENGSSSQQMDDLFDILIQSGEISAD 764
TP +L KE PP ++ PK+ SS++ + + + +
Sbjct: 1536 KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS 1595
Query: 765 FKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGL 824
KE P PSPK P PSP E A P P G+P+ P L+ S
Sbjct: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSP--EKGPATPAPKGTPTSPPVTPSSLKDSP-- 1651
Query: 825 PLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSST 875
P S+ + + + ++ L P E+ P P ST
Sbjct: 1652 ---------TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693
Score = 58.9 bits (141), Expect = 2e-08
Identities = 152/711 (21%), Positives = 227/711 (31%), Gaps = 115/711 (16%)
Query: 185 PPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPP 244
P PPS G P+ K PT + P + S K P PP
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA--------TPP 1249
Query: 245 DQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEALGSSG 304
K PP + L+ + + N + P PK G
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPP-SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 305 TPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPG--ALPANLDDMKVAELKQELKLR 362
P + + + S G P P G + + G LPA K K
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Query: 363 SLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLS-TGPAL 421
P + T P PA T K G A P+ + T PA+
Sbjct: 1369 PTPPAAT------------------PSHKGGPAMTPPSPKRGP---AIPSPKGDPTSPAV 1407
Query: 422 VAAGLAPAEVVVATVASSGVVKFGSTGSTPP-VSPTPSERSLLSTGDEN-----STPGDT 475
+ L+P + V G TPP V+P +++ ++ + S+ GD
Sbjct: 1408 IP--LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
Query: 476 FGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIE 535
VT P SP + ++ + S +P A + ++ K++
Sbjct: 1466 TLPAVTPP--------SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517
Query: 536 ALTRMLRQ-----KQQLVERLKLQLEQEKRAQQPA-PAPAPLGTPV----KQENSFSSCQ 585
A R L ++ L ++ PA P+P TP K+ + S +
Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSK 1577
Query: 586 LSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQ 645
+ P +P I P +P P P PE PA P+
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP---APK 1634
Query: 646 GPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQ---PSSQPGSPAPAPSA 702
G V P +L T V A P S G P + + + APAP +
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASV--TCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES 1692
Query: 703 QMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQP----KQQENGS----SSQQMDDLFDI 754
P+ PT +K P + + + P +NGS S+ L +
Sbjct: 1693 --------TPIITAPT---RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741
Query: 755 LIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQ------PSPSAELPQAAPPPPGS- 807
S + +A K+ P P++ +PL A P P + AAP PP S
Sbjct: 1742 QKDSSK-TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
Query: 808 -------PSLPGRLEDFLESSTGL-------PLLTSGHD------GPEPLS 838
P+LP + + FL SS GL PL + D PEP+S
Sbjct: 1801 PLAPSPVPTLPPK-QQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS 1850
Score = 53.9 bits (128), Expect = 7e-07
Identities = 138/657 (21%), Positives = 199/657 (30%), Gaps = 91/657 (13%)
Query: 186 PLLPPSLTNGTTIPTAKST----PTLIKQSQ-PKSASEKSQRSKKAKELKPKVKKLKYHQ 240
PL+P + N P+ ++T TL+ + PKS S KV + +
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758
Query: 241 YIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEA- 299
+ P + P DS + + L + + PP G A
Sbjct: 759 ALAPVASSPKECPTEDSGASATASSKGTLTYLA--DSPSPLGVSVSPQTKRPPTKKGSAG 816
Query: 300 -------LGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKV 352
L S +P S NS S G+ ++S + T P
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGS--------KDSPATTHSPTPPSPKGAPTPS 868
Query: 353 AELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPA 412
A K +LP T T + L ++ P APK A S+ + + A PA
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPKE--GPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 413 ARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTP 472
P + A +P A+ K G +P +PTP + P
Sbjct: 927 ------PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT---------PP 971
Query: 473 GDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDK 532
G SP + +P P+ G SP G
Sbjct: 972 SPKGGPATPSP------KGAPTPPAATPPSPKGGPATPSPKGAPTPP------------- 1012
Query: 533 QIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLG 592
A+T + A P+P +P TP+ + + P G
Sbjct: 1013 ---AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 593 PAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKG 652
P PSL T P A P P K P P+ P P P G
Sbjct: 1070 G--PATPSLKGAPT---PPAATPPSP-----KGGPATPSPKGAPMPPAATPPSPKG---G 1116
Query: 653 VAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQP 712
+A P T T + K + G+P P++ P SP + P P
Sbjct: 1117 LATPPHKGAPT-TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 713 LFGTPT---SLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPP 769
P+ L P G + P + G ++ G + PP
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS---------PKGAPTTPAATPP 1226
Query: 770 SLPGK-EKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLP 825
S G PSPK +P A PSP A PPP G+P+ P L+ P
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGG--PATPPPKGAPTPPAATPPSLKGGLATP 1281
Score = 35.0 bits (79), Expect = 0.32
Identities = 90/363 (24%), Positives = 129/363 (35%), Gaps = 89/363 (24%)
Query: 576 KQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEP- 634
+QE + + P+ A +L P PC+ AP + +A P P P
Sbjct: 13 EQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA-SPFPSPS 71
Query: 635 --------VPAPQLLLGPQGPSLIKGVAP--PTLITDSTGTHLVLTVTNKNADSPG-LSS 683
VP PQ G +L G AP PT + + G + SP L+
Sbjct: 72 TIASTPLEVPFPQ---SSSGTALPLGTAPEAPTFLPNLIGPPI----------SPAALAL 118
Query: 684 GSPQQPSSQPGSPAP-APSAQMDLE-HPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQEN 741
SP + G+P+ AP A + L H +Q P +LL PP A E+
Sbjct: 119 ASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTS-PPSVAVA--------ES 169
Query: 742 GSSSQQMDDLFDILIQSGEISADFKEPPS--LPG-KEKPSPKTV-------CGSPLAAQP 791
GS I E + + PS +P K PSP + C +P+A+
Sbjct: 170 GSVIT-----LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQ 224
Query: 792 SPSAELPQA-----------------------APPPPGSPSLPGRLED---FLESSTGLP 825
S A LPQ +P PGS SL G + S+ LP
Sbjct: 225 SGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLP 284
Query: 826 LLTSGHD--GPE-----PLSL---IDDLHSQMLSSTAILDHP-PSPMDTSELHFVPEPSS 874
++TS GP P+SL + LH S +L PS + + + S
Sbjct: 285 VVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHS 344
Query: 875 TMG 877
+ G
Sbjct: 345 STG 347
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 63.5 bits (153), Expect = 9e-10
Identities = 66/266 (24%), Positives = 96/266 (36%), Gaps = 44/266 (16%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSV 621
+QP+P P P P + + + Q PL + PF+ P T P PP
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270
Query: 622 VVKQEALQPEPEPVPAPQLLLGP----QGPSLIKGVAPPTLITDSTGTHLVLTVTNKNAD 677
V + ++ E P P PQ P PS PP G + ++ N +
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330
Query: 678 SP-------GLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEE 730
+P LSS +P PS P P P + E P P+ ++PPG
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS----ERPPPPV---------RDPPGRSG 377
Query: 731 AMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQ 790
+ P NGS+S+ + + +SG S P S P P + G+P
Sbjct: 378 PLPPPPPVSRNGSTSRALPATPQLPSRSGVDS-----PRSGPRPPLPPDRPSAGAP---- 428
Query: 791 PSPSAELPQAAPPPPGSPSLPGRLED 816
PPPP S S+ +D
Sbjct: 429 -----------PPPPPSTSIRNGFQD 443
Score = 38.5 bits (88), Expect = 0.029
Identities = 64/260 (24%), Positives = 89/260 (34%), Gaps = 61/260 (23%)
Query: 611 PCAVAPGPPSVVVKQEALQPEPE--PVPAPQLLLGPQGPSLIK--------GVAPPTLIT 660
P + PG S K + P PVP+P GP P + G P ++
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 661 DSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDL-------EHPLQ-- 711
T + + N SP + G P+QPS P +P P P + + PL
Sbjct: 186 PVPSTPRPIQSSPHNRGSPPVPGG-PRQPSPGP-TPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 712 -------PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISAD 764
PL TP+ L +PP + +P I +
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS-----------------------IHRE 280
Query: 765 FKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAP-PPPGSPSLPGRLE-------D 816
PP + P P T P A+ +P P + P PPP PS G E +
Sbjct: 281 AVPPPPPQNNKPPVPSTP--RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 817 FLESSTGLPLLTSGHDGPEP 836
SS+ PL + G GP P
Sbjct: 339 LSLSSSTPPLPSPGRSGPLP 358
Score = 36.2 bits (82), Expect = 0.15
Identities = 41/174 (23%), Positives = 56/174 (32%), Gaps = 20/174 (11%)
Query: 678 SPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPK 737
SPG SG P+ ++ P P ++ D P P+ TP + + P+
Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP--PVPSTPRPIQSSPHNRGSPPVPGGPR 211
Query: 738 QQENGSSSQQMDDLFDILIQSGEI-------SADFKEPPSLPGKEKPSPKTVCGSPLAAQ 790
Q G + + G I S+ F P LP P+P
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP----PTPSRALDDKPPPP 267
Query: 791 PSPSAELP----QAAPPPP---GSPSLPGRLEDFLESSTGLPLLTSGHDGPEPL 837
P P P +A PPPP P +P S P GP PL
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL 321
Score = 30.8 bits (68), Expect = 6.1
Identities = 43/148 (29%), Positives = 50/148 (33%), Gaps = 36/148 (24%)
Query: 107 PKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPM 166
P SS D + L + S +PSP S PL S P V P
Sbjct: 318 PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR---SGPLPPPPSERPPPPVRD-PP 373
Query: 167 GRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKA 226
GR PLPPPP P NG+T +TP L P + S RS
Sbjct: 374 GRSG----------PLPPPP---PVSRNGSTSRALPATPQL-----PSRSGVDSPRSGPR 415
Query: 227 KELKPKVKKLKYHQYIPPDQKQDRGAPP 254
L PPD + GAPP
Sbjct: 416 PPL-------------PPD-RPSAGAPP 429
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 63.5 bits (153), Expect = 9e-10
Identities = 66/266 (24%), Positives = 96/266 (36%), Gaps = 44/266 (16%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSV 621
+QP+P P P P + + + Q PL + PF+ P T P PP
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270
Query: 622 VVKQEALQPEPEPVPAPQLLLGP----QGPSLIKGVAPPTLITDSTGTHLVLTVTNKNAD 677
V + ++ E P P PQ P PS PP G + ++ N +
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330
Query: 678 SP-------GLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEE 730
+P LSS +P PS P P P + E P P+ ++PPG
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS----ERPPPPV---------RDPPGRSG 377
Query: 731 AMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQ 790
+ P NGS+S+ + + +SG S P S P P + G+P
Sbjct: 378 PLPPPPPVSRNGSTSRALPATPQLPSRSGVDS-----PRSGPRPPLPPDRPSAGAP---- 428
Query: 791 PSPSAELPQAAPPPPGSPSLPGRLED 816
PPPP S S+ +D
Sbjct: 429 -----------PPPPPSTSIRNGFQD 443
Score = 38.5 bits (88), Expect = 0.029
Identities = 64/260 (24%), Positives = 89/260 (34%), Gaps = 61/260 (23%)
Query: 611 PCAVAPGPPSVVVKQEALQPEPE--PVPAPQLLLGPQGPSLIK--------GVAPPTLIT 660
P + PG S K + P PVP+P GP P + G P ++
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 661 DSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDL-------EHPLQ-- 711
T + + N SP + G P+QPS P +P P P + + PL
Sbjct: 186 PVPSTPRPIQSSPHNRGSPPVPGG-PRQPSPGP-TPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 712 -------PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISAD 764
PL TP+ L +PP + +P I +
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS-----------------------IHRE 280
Query: 765 FKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAP-PPPGSPSLPGRLE-------D 816
PP + P P T P A+ +P P + P PPP PS G E +
Sbjct: 281 AVPPPPPQNNKPPVPSTP--RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 817 FLESSTGLPLLTSGHDGPEP 836
SS+ PL + G GP P
Sbjct: 339 LSLSSSTPPLPSPGRSGPLP 358
Score = 36.2 bits (82), Expect = 0.15
Identities = 41/174 (23%), Positives = 56/174 (32%), Gaps = 20/174 (11%)
Query: 678 SPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPK 737
SPG SG P+ ++ P P ++ D P P+ TP + + P+
Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP--PVPSTPRPIQSSPHNRGSPPVPGGPR 211
Query: 738 QQENGSSSQQMDDLFDILIQSGEI-------SADFKEPPSLPGKEKPSPKTVCGSPLAAQ 790
Q G + + G I S+ F P LP P+P
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP----PTPSRALDDKPPPP 267
Query: 791 PSPSAELP----QAAPPPP---GSPSLPGRLEDFLESSTGLPLLTSGHDGPEPL 837
P P P +A PPPP P +P S P GP PL
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL 321
Score = 30.8 bits (68), Expect = 6.1
Identities = 43/148 (29%), Positives = 50/148 (33%), Gaps = 36/148 (24%)
Query: 107 PKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPM 166
P SS D + L + S +PSP S PL S P V P
Sbjct: 318 PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR---SGPLPPPPSERPPPPVRD-PP 373
Query: 167 GRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKA 226
GR PLPPPP P NG+T +TP L P + S RS
Sbjct: 374 GRSG----------PLPPPP---PVSRNGSTSRALPATPQL-----PSRSGVDSPRSGPR 415
Query: 227 KELKPKVKKLKYHQYIPPDQKQDRGAPP 254
L PPD + GAPP
Sbjct: 416 PPL-------------PPD-RPSAGAPP 429
>gi|195963410 MEF2 activating motif and SAP domain containing
transcriptional regulator isoform 1 [Homo sapiens]
Length = 415
Score = 63.2 bits (152), Expect = 1e-09
Identities = 77/287 (26%), Positives = 114/287 (39%), Gaps = 59/287 (20%)
Query: 161 VSQLPMGRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQ-------P 213
V QL + R ++E + + P L P+L +GT P S L+ + + P
Sbjct: 20 VLQLRIHRRNQEQISDPDPWISASDPPLAPALPSGTA-PFLFSPGVLLPEPEYCPPWRSP 78
Query: 214 KSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQ 273
K S K S++ +E KP+ L YHQY+PP+ +Q A P A L+
Sbjct: 79 KKESPKI--SQRWRESKPR-GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTD 135
Query: 274 ILNQQQQQHHNYQAILPAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNS 333
+QQ + P PP G P S +P P L Q
Sbjct: 136 --SQQPHPRMKPSPLTPCPP----------GVP-------------SPSPPPHKLELQT- 169
Query: 334 TSLTGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRA-----------YQD 382
L+++ V+EL+Q+L+LR LPVSGTK+ L+ER+R +D
Sbjct: 170 -----------LKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRRED 218
Query: 383 QISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPA 429
+ P P A + + G V + + R A G APA
Sbjct: 219 SPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA 265
Score = 61.2 bits (147), Expect = 4e-09
Identities = 105/431 (24%), Positives = 156/431 (36%), Gaps = 74/431 (17%)
Query: 543 QKQQLVE---RLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHP--- 596
Q+ Q++ R LQL +R Q+ P P S PL PA P
Sbjct: 8 QRSQIIRSKFRSVLQLRIHRRNQEQISDPDPW------------ISASDPPLAPALPSGT 55
Query: 597 ----FNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPE----------PVPA----- 637
F+P + P + P +P S + Q + +P P P
Sbjct: 56 APFLFSPGVLLPEPEYCPPWR-SPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRA 114
Query: 638 -PQL---LLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQP 693
PQ LGP GPSL +G TDS H + + PG+ S SP +
Sbjct: 115 DPQAEGSALGPPGPSLWEG-------TDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLEL 167
Query: 694 GSPAPAPSAQMDLEHPLQ----PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMD 749
+ +L L+ P+ GT + LL++ G +P+++++ + +
Sbjct: 168 QTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAP-WP 226
Query: 750 DLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAP---PPPG 806
L + + K PS P P+ A P+P+ P AAP P G
Sbjct: 227 RLKPKALAAARRQGSVK--PSAASHRPPLPRAADTPGTAPAPTPTPA-PAAAPALTPSSG 283
Query: 807 SPSLPGRLEDFLESSTGLPLLTSGH-------DGPEPLSLIDDLHSQMLSSTAILDHPPS 859
S LE+ L+ + L D EP + + S +L P
Sbjct: 284 PGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPD 343
Query: 860 PMDTSELHF--VPEPSSTMGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDF 917
S + +P P+++ D DS+DWLE SGGP L P PS+FS D
Sbjct: 344 SEGLSSVFSSSLPSPTNSSSPSPRDP-TDSLDWLEALSGGPPLGSGP---PPPSIFSADL 399
Query: 918 LDGHDLQLHWD 928
D +L WD
Sbjct: 400 SDSSSSRL-WD 409
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 63.2 bits (152), Expect = 1e-09
Identities = 73/283 (25%), Positives = 98/283 (34%), Gaps = 40/283 (14%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPF-------NPSLAAPATNHIDPCAV 614
QQP P P P +++ + QP G P P + P T P A
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK--PPAQ 364
Query: 615 APGPPSVVVKQEALQPEPEPVPAPQLLLGPQG----PSLIKGVAPPTLITDSTGTHLVLT 670
GP +Q + P P+ L P G P+ G A P T GT L
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP--TQQVGTPKPLA 422
Query: 671 VTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM-------DLEHPLQPLFGTPTSLLKK 723
SP + G + P QPG P P+ Q P +P P+ L
Sbjct: 423 -QQPGLQSPAKAPGPTKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKP----PSQLPGP 476
Query: 724 EPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVC 783
P ++ +P Q+ GS+ Q G K PP PG KPSP+
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQ-------QPGST----KPPPQQPGPAKPSPQQP- 524
Query: 784 GSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPL 826
GS P + P A P P PS + ++ +G PL
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Score = 53.1 bits (126), Expect = 1e-06
Identities = 87/318 (27%), Positives = 109/318 (34%), Gaps = 65/318 (20%)
Query: 449 STPPVS-PTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGS 507
S PP+ PTP + G E S PG S LT+ L P + + P
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK-PLAQQPGTVKPPVQPPGTTK 360
Query: 508 CCLSPGGRA----ELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLK---------LQ 554
P G A + G +K Q K + + + Q K
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 555 LEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAV 614
L Q+ Q PA AP P TPV+Q ++ Q GP +A T P +
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQP---GPGKIPAQQAGPG-----KTSAQQTGPTKPPSQ 472
Query: 615 APGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNK 674
PGP K QP P P PQ P K PP+ S T
Sbjct: 473 LPGP----AKPPPQQPGPAKPP-------PQQPGSAK---PPSQQPGS---------TKP 509
Query: 675 NADSPGLSSGSPQQ------PSSQPGS-------PAPA-PSAQMDLEHPLQPLFGTPTSL 720
PG + SPQQ PS QPGS P+PA PSAQ + Q G P
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL-- 567
Query: 721 LKKEPPGYEEAMSQQPKQ 738
+PP + Q P Q
Sbjct: 568 ---QPPTVSPSAKQPPSQ 582
Score = 45.8 bits (107), Expect = 2e-04
Identities = 160/833 (19%), Positives = 264/833 (31%), Gaps = 116/833 (13%)
Query: 121 DALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQP 180
+++ P P+ + P+P + +P + P + +Q P G LA+QP
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ-PSGLTKP----LAQQP 346
Query: 181 PLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQ 240
PP+ PP T P + P + K +SE Q KA P V K
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE--QPGPKALAQPPGVGKT---- 400
Query: 241 YIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEAL 300
P Q+ PP QQ+ + Q Q A P P K+ +
Sbjct: 401 ---PAQQPGPAKPPT----------QQVGTPKPLAQQPGLQS---PAKAPGPTKTPVQQP 444
Query: 301 GSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELK 360
G P ++ S+ +G P + +PG PA + K
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG--PAKPPPQQPGSAKPP-- 500
Query: 361 LRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAAT--------SILHKAGEVVVAFPA 412
S TK Q P +P+ P +T S A + A P+
Sbjct: 501 --SQQPGSTKPP--------PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 413 ARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTP 472
A+ ST P P + S + S G + P + LL E +
Sbjct: 551 AQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN- 606
Query: 473 GDTFGEMVTSPLTQLTLQASPLQILVKE----------------------EGPRAGSCCL 510
+T E T+ + +P VKE P+ + +
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666
Query: 511 SPGGRAELEGRDKDQMLQEKD---KQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPA 567
+ Q +KD KQ + ++ LV++ L +A+QP A
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 568 PAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGP--PSVVVKQ 625
+ L P + + + P+ P P + P T+ + + P PS V+
Sbjct: 727 DS-LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 626 EALQPEPEPVPA----PQLLLGPQGPSLI--------------KGVAPPTLITDSTGTHL 667
+A + P+ P P G + K ++ P ++S G
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ 845
Query: 668 VLTVTNKNADSPGLSSGSPQ-----QPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLK 722
V V K + SP+ P P P P P+A + P Q S
Sbjct: 846 VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRF 905
Query: 723 KEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTV 782
G +++ PK Q LF I + S G+ P ++
Sbjct: 906 SLNLG---SITDAPKSQPTTPQETVTGKLFGF---GASIFSQASNLISTAGQPGPHSQSG 959
Query: 783 CGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDF-LESSTGLPLLTSGHDGPEPLSLID 841
G+P+ P+PS PP + P + ++ T P E +
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 842 DLHSQ-----MLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMD 889
++ + S ++ P + ++L P+P ST L + ++ S D
Sbjct: 1020 RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD 1072
Score = 39.3 bits (90), Expect = 0.017
Identities = 177/804 (22%), Positives = 260/804 (32%), Gaps = 114/804 (14%)
Query: 97 EAIIVGQVNYPKVADSSSFDEDSSDALSPEQ---PASHESQGSVPSPLEARVSEPLLSAT 153
EA + G+ +A +++ +S A SP PA E+ S S E R ++S
Sbjct: 4 EASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRA 63
Query: 154 SASPTQVVSQLPMGRDS--REMLFLAEQPPL----PPPPLLP--PSLTNGTTIPTAKSTP 205
P V S R+ + PP PP P P P L+ T T +S
Sbjct: 64 QGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQ 123
Query: 206 TL---------IKQSQPKSASEKSQRSKKAKELKPKVKKLK-----YHQYIPPDQKQDRG 251
L +K+S+ ++ ++ +S +V L +++ P D D
Sbjct: 124 KLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183
Query: 252 APPMDSSYA-KILQQQQLFLQLQILNQQQQQHHNYQAILPAP-PKSAG---EALGSSGTP 306
A +++ K++Q++Q + I QQQ P P PK G + L GTP
Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP-------PKPIPKQQGPGRDPLQQDGTP 236
Query: 307 PVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELKLRSLPV 366
+S+S+ P G Q T P A L + A Q + +
Sbjct: 237 --KSISSQQPEKIKSQPPGTGKPIQGPTQT---PQTDHAKLPLQRDASRPQTKQADIVRG 291
Query: 367 SGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAAR-------LSTGP 419
K L + Q P PG P A H+ + A P A+ L+ P
Sbjct: 292 ESVKPSLPSPSKPPIQQ--PTPGKPPAQQPG---HEKSQPGPAKPPAQPSGLTKPLAQQP 346
Query: 420 ALVAAGLAPAEVVVATVASSGVVK--FGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFG 477
V + P G K TGS P S P ++L TP G
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406
Query: 478 EMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGR---AELEGRDKDQMLQEKDKQI 534
P TQ PL + P S +PG + G K Q +
Sbjct: 407 P--AKPPTQQVGTPKPLA-----QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 535 EAL-TRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGP 593
A T + QL K +Q A+ P P P +Q S QQP GP
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP--QQP-GP 516
Query: 594 AHPF------------NPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLL 641
A P P A P+ P + + V Q +P
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Query: 642 LGPQGPSLIKGVAP-----------PTLITDSTGTHLVLTVTNKNADSPGLSSGSP---- 686
P L K + P P +T T TV + +P
Sbjct: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
Query: 687 ----QQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQ---PKQQ 739
Q + G AP PS+ + L+ T TS + K P ++ ++ PKQ
Sbjct: 637 CLNCQMKRALGGDLAPVPSSP---QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 740 -ENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELP 798
++ L G SA K+PP KP+P P +P A+
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD-- 751
Query: 799 QAAPPPPGSPSLPGRLEDFLESST 822
P P + D + SS+
Sbjct: 752 ----DKPKQPKMVKPTTDLVSSSS 771
Score = 31.2 bits (69), Expect = 4.7
Identities = 13/25 (52%), Positives = 15/25 (60%)
Query: 180 PPLPPPPLLPPSLTNGTTIPTAKST 204
PP PPPPL PP+ T +P K T
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLT 2444
Score = 30.8 bits (68), Expect = 6.1
Identities = 68/325 (20%), Positives = 110/325 (33%), Gaps = 71/325 (21%)
Query: 525 QMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSC 584
Q ++ + E +T R+ Q+++ L L + ++ P P TP + S C
Sbjct: 2134 QHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVP-PSDTPSLTSSVSSVC 2192
Query: 585 QLSQ---------------QPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQ 629
+P+ F S ++ + P ++ P + V +
Sbjct: 2193 TTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYF-PGSIIDYPEEISVSLDRTA 2251
Query: 630 PEPEPVPAPQLL--LGPQGPSLIKGVAPP-------TLITD--------------STGTH 666
P A ++ L S+I+ V P T+ TD TG
Sbjct: 2252 PPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNG 2311
Query: 667 LVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPP 726
++L V D L + + S+ P PS+ + L P++ T T E
Sbjct: 2312 IILEVLEAYRDKKELEAERTKSSLSETVFDHP-PSSVIAL--PMKEQLST-TYFTSGETF 2367
Query: 727 GYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSP 786
G E+ SQ P +GS S SLP K +P ++
Sbjct: 2368 GQEKPASQLP----SGSPSVS----------------------SLPAKPRPFFRS-SSLD 2400
Query: 787 LAAQPSPSAELPQAAPPPPGSPSLP 811
++AQP P P PPPP P P
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 30.8 bits (68), Expect = 6.1
Identities = 36/159 (22%), Positives = 65/159 (40%), Gaps = 26/159 (16%)
Query: 56 AKQLKLKRARLADDLNEKIAQRP-GPM-ELVEKNIL-----PVESSLKEA---IIVGQVN 105
A + + + +A + E + +P GP+ + V ++L PV+ + KE II+ +
Sbjct: 2259 ADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLE 2318
Query: 106 YPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLL-SATSASPTQVVSQL 164
+ D + + + + E H + P++ ++S S + + SQL
Sbjct: 2319 AYR--DKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQL 2376
Query: 165 PMGRDS-------------REMLFLAEQPPLPPPPLLPP 190
P G S L ++ QPP PPPP PP
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 63.2 bits (152), Expect = 1e-09
Identities = 73/283 (25%), Positives = 98/283 (34%), Gaps = 40/283 (14%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPF-------NPSLAAPATNHIDPCAV 614
QQP P P P +++ + QP G P P + P T P A
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK--PPAQ 364
Query: 615 APGPPSVVVKQEALQPEPEPVPAPQLLLGPQG----PSLIKGVAPPTLITDSTGTHLVLT 670
GP +Q + P P+ L P G P+ G A P T GT L
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP--TQQVGTPKPLA 422
Query: 671 VTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM-------DLEHPLQPLFGTPTSLLKK 723
SP + G + P QPG P P+ Q P +P P+ L
Sbjct: 423 -QQPGLQSPAKAPGPTKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKP----PSQLPGP 476
Query: 724 EPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVC 783
P ++ +P Q+ GS+ Q G K PP PG KPSP+
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQ-------QPGST----KPPPQQPGPAKPSPQQP- 524
Query: 784 GSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPL 826
GS P + P A P P PS + ++ +G PL
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Score = 53.1 bits (126), Expect = 1e-06
Identities = 87/318 (27%), Positives = 109/318 (34%), Gaps = 65/318 (20%)
Query: 449 STPPVS-PTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGS 507
S PP+ PTP + G E S PG S LT+ L P + + P
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK-PLAQQPGTVKPPVQPPGTTK 360
Query: 508 CCLSPGGRA----ELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLK---------LQ 554
P G A + G +K Q K + + + Q K
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 555 LEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAV 614
L Q+ Q PA AP P TPV+Q ++ Q GP +A T P +
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQP---GPGKIPAQQAGPG-----KTSAQQTGPTKPPSQ 472
Query: 615 APGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNK 674
PGP K QP P P PQ P K PP+ S T
Sbjct: 473 LPGP----AKPPPQQPGPAKPP-------PQQPGSAK---PPSQQPGS---------TKP 509
Query: 675 NADSPGLSSGSPQQ------PSSQPGS-------PAPA-PSAQMDLEHPLQPLFGTPTSL 720
PG + SPQQ PS QPGS P+PA PSAQ + Q G P
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL-- 567
Query: 721 LKKEPPGYEEAMSQQPKQ 738
+PP + Q P Q
Sbjct: 568 ---QPPTVSPSAKQPPSQ 582
Score = 45.8 bits (107), Expect = 2e-04
Identities = 160/833 (19%), Positives = 264/833 (31%), Gaps = 116/833 (13%)
Query: 121 DALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQP 180
+++ P P+ + P+P + +P + P + +Q P G LA+QP
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ-PSGLTKP----LAQQP 346
Query: 181 PLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQ 240
PP+ PP T P + P + K +SE Q KA P V K
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE--QPGPKALAQPPGVGKT---- 400
Query: 241 YIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEAL 300
P Q+ PP QQ+ + Q Q A P P K+ +
Sbjct: 401 ---PAQQPGPAKPPT----------QQVGTPKPLAQQPGLQS---PAKAPGPTKTPVQQP 444
Query: 301 GSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELK 360
G P ++ S+ +G P + +PG PA + K
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG--PAKPPPQQPGSAKPP-- 500
Query: 361 LRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAAT--------SILHKAGEVVVAFPA 412
S TK Q P +P+ P +T S A + A P+
Sbjct: 501 --SQQPGSTKPP--------PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 413 ARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTP 472
A+ ST P P + S + S G + P + LL E +
Sbjct: 551 AQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN- 606
Query: 473 GDTFGEMVTSPLTQLTLQASPLQILVKE----------------------EGPRAGSCCL 510
+T E T+ + +P VKE P+ + +
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666
Query: 511 SPGGRAELEGRDKDQMLQEKD---KQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPA 567
+ Q +KD KQ + ++ LV++ L +A+QP A
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 568 PAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGP--PSVVVKQ 625
+ L P + + + P+ P P + P T+ + + P PS V+
Sbjct: 727 DS-LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 626 EALQPEPEPVPA----PQLLLGPQGPSLI--------------KGVAPPTLITDSTGTHL 667
+A + P+ P P G + K ++ P ++S G
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ 845
Query: 668 VLTVTNKNADSPGLSSGSPQ-----QPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLK 722
V V K + SP+ P P P P P+A + P Q S
Sbjct: 846 VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRF 905
Query: 723 KEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTV 782
G +++ PK Q LF I + S G+ P ++
Sbjct: 906 SLNLG---SITDAPKSQPTTPQETVTGKLFGF---GASIFSQASNLISTAGQPGPHSQSG 959
Query: 783 CGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDF-LESSTGLPLLTSGHDGPEPLSLID 841
G+P+ P+PS PP + P + ++ T P E +
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 842 DLHSQ-----MLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMD 889
++ + S ++ P + ++L P+P ST L + ++ S D
Sbjct: 1020 RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD 1072
Score = 39.3 bits (90), Expect = 0.017
Identities = 177/804 (22%), Positives = 260/804 (32%), Gaps = 114/804 (14%)
Query: 97 EAIIVGQVNYPKVADSSSFDEDSSDALSPEQ---PASHESQGSVPSPLEARVSEPLLSAT 153
EA + G+ +A +++ +S A SP PA E+ S S E R ++S
Sbjct: 4 EASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRA 63
Query: 154 SASPTQVVSQLPMGRDS--REMLFLAEQPPL----PPPPLLP--PSLTNGTTIPTAKSTP 205
P V S R+ + PP PP P P P L+ T T +S
Sbjct: 64 QGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQ 123
Query: 206 TL---------IKQSQPKSASEKSQRSKKAKELKPKVKKLK-----YHQYIPPDQKQDRG 251
L +K+S+ ++ ++ +S +V L +++ P D D
Sbjct: 124 KLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183
Query: 252 APPMDSSYA-KILQQQQLFLQLQILNQQQQQHHNYQAILPAP-PKSAG---EALGSSGTP 306
A +++ K++Q++Q + I QQQ P P PK G + L GTP
Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP-------PKPIPKQQGPGRDPLQQDGTP 236
Query: 307 PVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELKLRSLPV 366
+S+S+ P G Q T P A L + A Q + +
Sbjct: 237 --KSISSQQPEKIKSQPPGTGKPIQGPTQT---PQTDHAKLPLQRDASRPQTKQADIVRG 291
Query: 367 SGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAAR-------LSTGP 419
K L + Q P PG P A H+ + A P A+ L+ P
Sbjct: 292 ESVKPSLPSPSKPPIQQ--PTPGKPPAQQPG---HEKSQPGPAKPPAQPSGLTKPLAQQP 346
Query: 420 ALVAAGLAPAEVVVATVASSGVVK--FGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFG 477
V + P G K TGS P S P ++L TP G
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406
Query: 478 EMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGR---AELEGRDKDQMLQEKDKQI 534
P TQ PL + P S +PG + G K Q +
Sbjct: 407 P--AKPPTQQVGTPKPLA-----QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 535 EAL-TRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGP 593
A T + QL K +Q A+ P P P +Q S QQP GP
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP--QQP-GP 516
Query: 594 AHPF------------NPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLL 641
A P P A P+ P + + V Q +P
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Query: 642 LGPQGPSLIKGVAP-----------PTLITDSTGTHLVLTVTNKNADSPGLSSGSP---- 686
P L K + P P +T T TV + +P
Sbjct: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
Query: 687 ----QQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQ---PKQQ 739
Q + G AP PS+ + L+ T TS + K P ++ ++ PKQ
Sbjct: 637 CLNCQMKRALGGDLAPVPSSP---QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 740 -ENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELP 798
++ L G SA K+PP KP+P P +P A+
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD-- 751
Query: 799 QAAPPPPGSPSLPGRLEDFLESST 822
P P + D + SS+
Sbjct: 752 ----DKPKQPKMVKPTTDLVSSSS 771
Score = 31.2 bits (69), Expect = 4.7
Identities = 13/25 (52%), Positives = 15/25 (60%)
Query: 180 PPLPPPPLLPPSLTNGTTIPTAKST 204
PP PPPPL PP+ T +P K T
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLT 2444
Score = 30.8 bits (68), Expect = 6.1
Identities = 68/325 (20%), Positives = 110/325 (33%), Gaps = 71/325 (21%)
Query: 525 QMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSC 584
Q ++ + E +T R+ Q+++ L L + ++ P P TP + S C
Sbjct: 2134 QHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVP-PSDTPSLTSSVSSVC 2192
Query: 585 QLSQ---------------QPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQ 629
+P+ F S ++ + P ++ P + V +
Sbjct: 2193 TTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYF-PGSIIDYPEEISVSLDRTA 2251
Query: 630 PEPEPVPAPQLL--LGPQGPSLIKGVAPP-------TLITD--------------STGTH 666
P A ++ L S+I+ V P T+ TD TG
Sbjct: 2252 PPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNG 2311
Query: 667 LVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPP 726
++L V D L + + S+ P PS+ + L P++ T T E
Sbjct: 2312 IILEVLEAYRDKKELEAERTKSSLSETVFDHP-PSSVIAL--PMKEQLST-TYFTSGETF 2367
Query: 727 GYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSP 786
G E+ SQ P +GS S SLP K +P ++
Sbjct: 2368 GQEKPASQLP----SGSPSVS----------------------SLPAKPRPFFRS-SSLD 2400
Query: 787 LAAQPSPSAELPQAAPPPPGSPSLP 811
++AQP P P PPPP P P
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 30.8 bits (68), Expect = 6.1
Identities = 36/159 (22%), Positives = 65/159 (40%), Gaps = 26/159 (16%)
Query: 56 AKQLKLKRARLADDLNEKIAQRP-GPM-ELVEKNIL-----PVESSLKEA---IIVGQVN 105
A + + + +A + E + +P GP+ + V ++L PV+ + KE II+ +
Sbjct: 2259 ADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLE 2318
Query: 106 YPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLL-SATSASPTQVVSQL 164
+ D + + + + E H + P++ ++S S + + SQL
Sbjct: 2319 AYR--DKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQL 2376
Query: 165 PMGRDS-------------REMLFLAEQPPLPPPPLLPP 190
P G S L ++ QPP PPPP PP
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 62.0 bits (149), Expect = 2e-09
Identities = 114/474 (24%), Positives = 168/474 (35%), Gaps = 72/474 (15%)
Query: 385 SPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKF 444
SP+ +P +P S A E ++ P P + L+P + T +
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL 572
Query: 445 GSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPR 504
P+SP P E S +S E S F E SP + SPL P
Sbjct: 573 SPPPEESPMSP-PPEESPMSPPPEASRLFPPFEESPLSP----PPEESPL-------SPP 620
Query: 505 AGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQP 564
+ LSP ++ ++ L+ + +V RL P
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL-----PVVSRL-----------SP 664
Query: 565 APAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPP----- 619
P +PL P E S +S L P +P+ P + P PP
Sbjct: 665 PPEESPLSPP--PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP------PPEDSLM 716
Query: 620 SVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSP 679
S+ +++ L P PE PQL +GP L P L HL + A+ P
Sbjct: 717 SLPLEESPLLPLPE---EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL-----SPQAEEP 768
Query: 680 GLS--------SGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEA 731
LS P++P P + P S Q + H L P P P E
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH-LSPQTEEP----HLSPVPEEPC 823
Query: 732 MSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEK--------PSPKTVC 783
+S QP +E+ S Q + + +S + ++PP P EK P+P+ +
Sbjct: 824 LSPQP--EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881
Query: 784 GSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPL 837
P +PS S L + A PG P L E+ S +G P L+ P+PL
Sbjct: 882 LFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL 935
Score = 55.1 bits (131), Expect = 3e-07
Identities = 157/698 (22%), Positives = 244/698 (34%), Gaps = 137/698 (19%)
Query: 209 KQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQL 268
KQ K A + + K ++ K + + +KQ + + + Y QQQQ
Sbjct: 3545 KQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQ- 3603
Query: 269 FLQLQILNQQQQQHHNYQAILPAPP-----KSAGEALGSSGTPPVRSLS---------TT 314
Q QQQQQH A+ P+ K G+ L G P + T
Sbjct: 3604 ----QQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTP 3659
Query: 315 NSSSSSGAPGP----CGLARQNSTSLTGKPGAL--------PANLDDMKVAELKQELKLR 362
+ G PG LA+Q +G G+L P NL + + L+ R
Sbjct: 3660 GGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQER 3719
Query: 363 SLPVSGTKTELIERLR----------------AYQDQISPVPGA-------PKAPAATSI 399
L + + +L ++L+ A Q Q PG PK
Sbjct: 3720 QLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPP 3779
Query: 400 LHKAGEVVVAFPAARLSTGPALVAAG-LAPAEVVVATVASSGVVKFGSTGSTPPVSPTPS 458
G +V +LS P G L PA+V V G + G G V T S
Sbjct: 3780 SSHQGLLV-----QQLSPQPPQGPQGMLGPAQVAVLQQQHPGAL--GPQGPHRQVLMTQS 3832
Query: 459 ERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQ------ASPLQILVKEEGPRAGSCCLSP 512
R L S G +VT+ Q Q + L L + +G LS
Sbjct: 3833 -RVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSA 3891
Query: 513 GGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQP-----APA 567
L+ + Q LQ++ + + + L+Q+QQL ++ Q +Q+++ QQ
Sbjct: 3892 QPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ 3951
Query: 568 PAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEA 627
L +Q+ Q QQ +G + + +L +P A+ PG P+ +
Sbjct: 3952 QQQLQQQQQQQQQQFQQQQQQQQMGLLNQ-SRTLLSPQQQQQQQVALGPGMPA-----KP 4005
Query: 628 LQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQ 687
LQ P G GP+L+ LT +N P +SS + +
Sbjct: 4006 LQHFSSP--------GALGPTLL------------------LTGKEQNTVDPAVSSEATE 4039
Query: 688 QPSSQPGSP---APAPSAQMDLEHPLQPLFGTPTSLL--KKEPPGYEEAMSQQPKQQENG 742
PS+ G P P + ++P + LL + +P ++ QP + G
Sbjct: 4040 GPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPG 4099
Query: 743 SSSQQMDDLFDI------LIQSGEISADFKEP-----PSLPGKEKPSPKT--VCG--SPL 787
QQ+ L + SG S P PS+ ++P T + G P+
Sbjct: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPM 4159
Query: 788 AAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLP 825
+P + PQ PP PG L+S GLP
Sbjct: 4160 LERPMQNNTGPQ--PPKPG---------PVLQSGQGLP 4186
Score = 47.8 bits (112), Expect = 5e-05
Identities = 106/412 (25%), Positives = 147/412 (35%), Gaps = 68/412 (16%)
Query: 452 PVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVK-----EEGPRAG 506
P+SP P E S LS E+S E SP +++ + SPL ++ + EE P +
Sbjct: 616 PLSPPP-EASRLSPPPEDSPMSPPPEESPMSPPPEVS-RLSPLPVVSRLSPPPEESPLSP 673
Query: 507 SCCLSP------GGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEK- 559
SP R D +D L E L L +E
Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733
Query: 560 ---RAQQP--APAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAA-PATNHIDPCA 613
R++ P +P P + E S Q + L P P P L A P H+ P A
Sbjct: 734 LCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP-QPEEPCLCAVPEEPHLSPQA 792
Query: 614 ----VAPGPPSVVVKQEALQPEPEPVPA-PQLLLGPQGPSLIKGVAPPTLITDSTGTHLV 668
++P P + + + +P PVP P L P+ L P L +HL
Sbjct: 793 EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHL- 851
Query: 669 LTVTNKNADSPGLSSGSPQQPSSQPGS-PAPA--PSAQMDLEHPLQPLFGTPTSLLKKEP 725
+ + P LS P++P +PG PAP P E L PL G P EP
Sbjct: 852 ----SPELEKPPLSP-RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP 906
Query: 726 P--GYEEAMSQQPKQQENGSSSQQMDD-----LFDILIQS--------GEISADF----- 765
P E + P + + S D L I+ + GE+ F
Sbjct: 907 PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGD 966
Query: 766 ---KEPPSLPGKE---KPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLP 811
+ P + P E P P+ C P +P P P PP PGSP P
Sbjct: 967 SDPESPLAAPILETPISPPPEANCTDP---EPVP----PMILPPSPGSPVGP 1011
Score = 47.0 bits (110), Expect = 8e-05
Identities = 79/325 (24%), Positives = 116/325 (35%), Gaps = 31/325 (9%)
Query: 550 RLKLQLE---QEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPAT 606
+L+ QLE E+ P P +PL P ++ + + S+ L P P+ P
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASR--LSPPPEELPASPLPEA 482
Query: 607 NHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTH 666
H+ + P S ++ L P PE P L P P + P L T +
Sbjct: 483 LHLSR-PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE-ESPPSPALETPLSPPP 540
Query: 667 LVLTVTNKNADSPGLSSGSPQQPSSQPG-----SPAP--APSAQMDLEHPLQPLFGTPTS 719
++ +SP LS + P+S P SP P +P + E P+ P P
Sbjct: 541 EASPLSPPFEESP-LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP----PPE 595
Query: 720 LLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSP 779
+ PP E +S P++ + L E S P P P
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLSPPPEASR-----LSPPPEDSPMSPPPEESPMSPPPEV 650
Query: 780 KTVCGSPLAAQPSPSAELPQAAPPPPGSPSLP----GRLEDFLESSTGLPLLTSGHDGPE 835
+ P+ ++ SP E +PPP SP+ P RL E S P D P
Sbjct: 651 SRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS---PTSPPPEDSPA 707
Query: 836 PLSLIDDLHSQMLSSTAILDHPPSP 860
D L S L + +L P P
Sbjct: 708 SPPPEDSLMSLPLEESPLLPLPEEP 732
Score = 46.6 bits (109), Expect = 1e-04
Identities = 115/483 (23%), Positives = 171/483 (35%), Gaps = 142/483 (29%)
Query: 521 RDKDQMLQEKDKQIEALTRMLRQKQQ---LVERLKLQLEQEKRAQQPAPAPAPLGTPVKQ 577
+ + Q LQ++ +Q + + +Q+QQ L + L Q+++ QQ A P G P K
Sbjct: 3949 QQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP---GMPAKP 4005
Query: 578 ENSFSSCQLSQQPLGPA--------HPFNPSLAA-----PATNHIDPCAVAPGPPSVVVK 624
FSS LGP + +P++++ P+T+ P A+ P S+ +
Sbjct: 4006 LQHFSS----PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATE 4061
Query: 625 QEAL-------------QPEPEPVPAPQLLLGP--------QGPSLIK---GVAPPTLIT 660
+ QP+P+P P+ L P Q SL+ G + L +
Sbjct: 4062 PGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGS 4121
Query: 661 DSTGT-----HLVLTVTNKNADSPGLSSGS---PQQP--------SSQPGSPAPAPSAQM 704
S+ HL+ + D PG + + PQQP ++ P P P P Q
Sbjct: 4122 GSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQS 4181
Query: 705 DLEHP---LQPLFG-------------------TPT------SLLKKEPPGYEEAMSQQP 736
P + P G +P +LL + +A+ Q P
Sbjct: 4182 GQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTP 4241
Query: 737 KQQENGSSSQQMDDLFDILIQSG-----------EISADFKE--PPSLP----------- 772
QE G+ + + L Q G E+ A + PP LP
Sbjct: 4242 PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPV 4301
Query: 773 -GKEKPSPKTVCGSPLAAQ-----PSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPL 826
G P+P SP + PSPS++LP A PP P P LE
Sbjct: 4302 LGPVHPTPPP--SSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEP------ 4353
Query: 827 LTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLD 886
G P L D L S+ L P P D PE SS L GHLD
Sbjct: 4354 -PPGRVSPAAAQLADTLFSKGLG-------PWDPPDNLAETQKPEQSS-----LVPGHLD 4400
Query: 887 SMD 889
++
Sbjct: 4401 QVN 4403
Score = 42.0 bits (97), Expect = 0.003
Identities = 129/589 (21%), Positives = 205/589 (34%), Gaps = 96/589 (16%)
Query: 203 STPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKI 262
S L +Q Q + + Q+ ++ + + ++++ + Q Q Q + + +
Sbjct: 3896 SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQ- 3954
Query: 263 LQQQQLFLQLQILNQQQQQHH---NYQAILPAPPKSAGEALGSSGTPPVRSLSTTNSSSS 319
LQQQQ Q Q QQQQQ N L +P + + + P + L SS
Sbjct: 3955 LQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPL---QHFSS 4011
Query: 320 SGAPGPCGLARQNSTSLTGK-----PGALPANLDDMKVAELKQELKLRSLPVS-GTKTEL 373
GA GP L LTGK A+ + + L + + P S T+
Sbjct: 4012 PGALGPTLL-------LTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGE 4064
Query: 374 IERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVV 433
++ + Q+ V P+ ++ L P L G +V +
Sbjct: 4065 VKPSLSGDSQLLLVQPQPQPQPSS-----------------LQLQPPLRLPGQQQQQVSL 4107
Query: 434 ATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPL-TQLTLQAS 492
A G +GS+ S P LL+ + + GD G M + L Q +
Sbjct: 4108 LHTAGGGSHGQLGSGSSSEASSVP---HLLA--QPSVSLGDQPGSMTQNLLGPQQPMLER 4162
Query: 493 PLQILVKEEGPRAGSCCLSPGG-------------RAELEGRDKDQMLQEKDKQIEALTR 539
P+Q + P+ G S G RA+L+G + K+ Q+ L+
Sbjct: 4163 PMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQG------VLAKNPQLRHLSP 4216
Query: 540 MLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQ-------------L 586
+Q+ Q + ++ QL+Q + +Q P P GT CQ L
Sbjct: 4217 QQQQQLQAL-LMQRQLQQSQAVRQTPPYQEP-GTQTSPLQGLLGCQPQLGGFPGPQTGPL 4274
Query: 587 SQQPLGPAHPFNPSLAAPATNHIDPCAVAPGP--------PSVVVKQEALQPEPEPVPAP 638
+ GP P L AP P A++ GP P QE +P P P+
Sbjct: 4275 QELGAGPRPQGPPRLPAP------PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 639 QLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNAD---SPGLSSGSPQQPSSQPGS 695
QL Q P G P T V + AD S GL P ++
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQK 4388
Query: 696 PAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAM--SQQPKQQENG 742
P + L+ + + L K+ P E +Q K++ NG
Sbjct: 4389 PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANG 4437
Score = 41.6 bits (96), Expect = 0.003
Identities = 166/711 (23%), Positives = 258/711 (36%), Gaps = 165/711 (23%)
Query: 57 KQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFD 116
K + + RL + NEK A+R + VE L E P AD+S
Sbjct: 3063 KDIFNEHLRLVESANEK-AEREALLRGVEPGPLGPEE-----------RPPPAADAS--- 3107
Query: 117 EDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLP----MG-RDSR 171
E ++ PE E G PSP + ++ P + A+ + + P MG RD+R
Sbjct: 3108 EPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTR 3167
Query: 172 -------EMLFLAEQPPL-----PPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSAS-- 217
AE+ PP LL PS +G P S L+++ + +S +
Sbjct: 3168 MGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSG---PGGSS---LLEKFELESGALT 3221
Query: 218 ------------EKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQ 265
+K + S A EL ++ L H+ ++ ++
Sbjct: 3222 LPGGPAASGDELDKMESSLVASELPLLIEDLLEHEK------------------KELQKK 3263
Query: 266 QQLFLQLQILNQQQQQHHNYQAILPAP--------------PKSAGE----ALGSSGT-- 305
QQL QLQ QQQQQ + ++L AP P AG +LG +G
Sbjct: 3264 QQLSAQLQPAQQQQQQQQQH-SLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQ 3322
Query: 306 -----------PPVRSL-----------STTNSSSSSGAPGPCGLARQNSTS--LTGKP- 340
PP +L S S G GL Q S+ L+ KP
Sbjct: 3323 PGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPM 3382
Query: 341 GALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPV--------PGAPK 392
G +P ++ MK +L + +L + T + A +D I P+ G K
Sbjct: 3383 GTMPPSM-CMKPQQLAMQQQLANSFFPDTDLDKF----AAEDIIDPIAKAKMVALKGIKK 3437
Query: 393 APAATSILHKAG--EVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGST 450
A SI G V+ A RLS GP+ +++ A SG + S
Sbjct: 3438 VMAQGSIGVAPGMNRQQVSLLAQRLSGGPS--------SDLQNHVAAGSGQERSAGDPSQ 3489
Query: 451 PPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCL 510
P +P + +++ D+ F T L Q+ L+ QI V + +A
Sbjct: 3490 PRPNPPTFAQGVINEADQRQYEEWLFH---TQQLLQMQLKVLEEQIGVHRKSRKALCAKQ 3546
Query: 511 SPGGRAELEGRDKD----QMLQEKDKQIEALTRMLRQKQQ-----LVE-RLKLQLEQEKR 560
+A E + D +++ E+ +I+ +R++Q+ + E R K Q +Q+++
Sbjct: 3547 RTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQ 3606
Query: 561 AQQPAPAPAPLGTPVKQENSFSSCQLSQQP--LGPAHPFNPSLAAPATN----HIDPCAV 614
QQ A L Q S L++ P L P H P P + P +
Sbjct: 3607 QQQQQQHSAVLALSPSQ----SPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGM 3662
Query: 615 A-PGPPSVVVKQEAL--QPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDS 662
A PG P AL Q + + L GP G +A +L DS
Sbjct: 3663 ALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713
Score = 41.2 bits (95), Expect = 0.005
Identities = 71/327 (21%), Positives = 106/327 (32%), Gaps = 30/327 (9%)
Query: 551 LKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPL-----GPAHP------FNP 599
L L+L + AQ P+ P L E F + + P PA P P
Sbjct: 2159 LFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP 2218
Query: 600 SLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVP-APQL--LLGPQGPSLIKGVAPP 656
P H P PG P + + P+P P P L L P+ P + G A
Sbjct: 2219 GAGQPGEFHTTP----PGTP----RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASE 2270
Query: 657 TLITDST--GTHLVLTVTNKNADSPGLSSGSPQQPS-SQPGSPAPAPSAQMDLEHPLQPL 713
L++ + L V + + S G P P S ++ +
Sbjct: 2271 PLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAP 2330
Query: 714 FGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPG 773
S ++ + PG + P Q S D+F + G + + +PP P
Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIF----RPGSYTDPYAQPPLTPR 2386
Query: 774 KEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDG 833
+ P P++ C P + PS A+P S P + +T
Sbjct: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446
Query: 834 PEPLSLIDDLHSQMLSSTAILDHPPSP 860
P+P S Q A L PP P
Sbjct: 2447 PDPYSR-PPSRPQSRDPFAPLHKPPRP 2472
Score = 38.5 bits (88), Expect = 0.029
Identities = 173/828 (20%), Positives = 258/828 (31%), Gaps = 170/828 (20%)
Query: 46 EETSAEPSLQAKQLK--LKRARLADDLNEKIAQRP------GPMELVEKNILPVESSLKE 97
EE A P +A L L+ + L+ E P P+E E + P E S
Sbjct: 472 EELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLE--ESPLSPPEESPPS 529
Query: 98 AIIVGQVNYPKVAD--SSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSA 155
+ ++ P A S F+E SP P E S P P +R+S P + +
Sbjct: 530 PALETPLSPPPEASPLSPPFEE------SPLSPPPEELPTS-PPPEASRLSPPPEESPMS 582
Query: 156 SPTQVVSQLPMGRDSREMLFLAEQPPLPPP---PLLPPSLTNGTTIPTAKSTPTLIKQSQ 212
P + P SR E P PPP PL PP + + P S + +
Sbjct: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
Query: 213 PKS-------------------ASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAP 253
P S E+S S +E P + + PP + P
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE-SPTSPPPEASRLSPPPEDSPTSPP 701
Query: 254 PMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAP------PKSAGEALGSSGTPP 307
P DS + + + L L+ +LP P P+S G L P
Sbjct: 702 PEDSPASPPPEDSLMSLPLE-----------ESPLLPLPEEPQLCPRSEGPHLSPRPEEP 750
Query: 308 VRSLSTTNSSSSSGAPGP-----------CGLARQNSTSLTGKPGALPANLDDMKVAELK 356
S S A P C + + S + L +++ ++
Sbjct: 751 HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQT 810
Query: 357 QELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLS 416
+E L +P + E + +SP P H + E+ + R
Sbjct: 811 EEPHLSPVPEEPCLSPQPE-----ESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
Query: 417 TGPALVAAGLAPAEVVVATVASS-------GVVKFGSTGSTPPVSPTPSERSLLSTGDEN 469
P AP E+ + G G P +SP P E L +G+ +
Sbjct: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP-LSPLPEELPLSPSGEPS 924
Query: 470 STPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQE 529
+P + + PL+ + A+P LSP G E K E
Sbjct: 925 LSPQLMPPDPLPPPLSPIITAAAP--------------PALSPLGELEYPFGAKGDSDPE 970
Query: 530 KDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQ 589
L + E P P P + L
Sbjct: 971 SPLAAPIL------------ETPISPPPEANCTDPEPVPPMI--------------LPPS 1004
Query: 590 PLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPE---PEPVPAPQLLLGPQG 646
P P P +P L P P + Q +L P+ P P L L
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSP-----------LLQHSLVPQNSPPSQCSPPALPLSV-- 1051
Query: 647 PSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGL--SSGSP-QQPSSQPGSPAPAPSAQ 703
PS + + ++D H + T + P L S+ SP P PAP+P+
Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPA 1111
Query: 704 MD----LEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSG 759
+D L PL G + PG + Q P GS + ++ +L+
Sbjct: 1112 LDDFSGLGEDTAPLDGI-------DAPGSQPEPGQTP-----GSLASELKG-SPVLLDPE 1158
Query: 760 EISADFKEPPSLPGKEKPSPKTVC--GSPLAAQPSPSAELPQAAPPPP 805
E++ P P + P K GSP Q P A + AP PP
Sbjct: 1159 ELA------PVTPMEVYPECKQTAGQGSPCEEQEEPRAPV---APTPP 1197
Score = 34.7 bits (78), Expect = 0.42
Identities = 42/167 (25%), Positives = 67/167 (40%), Gaps = 40/167 (23%)
Query: 495 QILVKEEGPRAGSC-----CLSPGGRAE-LEGRDKD---QMLQEKDKQIEALTRMLRQKQ 545
++L E RAG+ PGG+ + LEG+ D L++ D + T
Sbjct: 4816 EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYT------- 4868
Query: 546 QLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLS---------QQPLGPAHP 596
LK QL+ +Q +PAP P P + +++ L ++P P P
Sbjct: 4869 -----LKSQLDILSLLKQESPAPEP---PTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP 4920
Query: 597 FNPSLAAPATNHI-----DPCA--VAPGPPSVVVKQEALQPEPEPVP 636
PS A+P T + +P A P P + E+ +P+P P
Sbjct: 4921 LAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967
Score = 34.3 bits (77), Expect = 0.55
Identities = 37/146 (25%), Positives = 49/146 (33%), Gaps = 60/146 (41%)
Query: 670 TVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYE 729
T N D LS+ P++PS P AP+P++ P +PL PT L EPP
Sbjct: 4895 TYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASP-----PTEPLVELPTEPL-AEPP--- 4945
Query: 730 EAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAA 789
PSP + SP +A
Sbjct: 4946 ----------------------------------------------VPSPLPLASSPESA 4959
Query: 790 QPSPSAELPQAAPPPPGSPSLPGRLE 815
+P P+A PP G S P RL+
Sbjct: 4960 RPK-----PRARPPEEGEDSRPPRLK 4980
Score = 32.7 bits (73), Expect = 1.6
Identities = 53/221 (23%), Positives = 79/221 (35%), Gaps = 53/221 (23%)
Query: 3 PLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLK 62
PL SP F E R++LE + E P + ++ S+ L +LK
Sbjct: 2271 PLLSPPPFGESRKALEVKKEELGASSPSYGPPN------LGFVDSPSSGTHLGGLELKTP 2324
Query: 63 ---RARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDE-- 117
+A L ++ Q PG + P E +A+ ++P + S+ +
Sbjct: 2325 DVFKAPLTPRASQVEPQSPG------LGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPY 2378
Query: 118 --------------DSSDALSPEQ---------PASHESQGSVPSPLEARVSEPLLSATS 154
+S AL P PAS +SQ S SPL R LSA +
Sbjct: 2379 AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP----LSAEA 2434
Query: 155 ASPTQVV---------SQLPMGRDSREMLFLAEQPPLPPPP 186
P+ V S+ P SR+ +PP P PP
Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPP 2475
Score = 32.0 bits (71), Expect = 2.8
Identities = 95/425 (22%), Positives = 144/425 (33%), Gaps = 88/425 (20%)
Query: 388 PGAPKAPAATSILH--KAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFG 445
P APAA S+ K G+ ++ R+ TGP + A FG
Sbjct: 3139 PKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEK------------ASFG 3186
Query: 446 STGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRA 505
+TG P TPS S G +S L + L++ L +
Sbjct: 3187 ATGGPPAHLLTPSPLS---------------GPGGSSLLEKFELESGALTL--------- 3222
Query: 506 GSCCLSPGGRA----ELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRA 561
PGG A EL+ + + E IE L +++ Q ++L QL+ ++
Sbjct: 3223 ------PGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQ 3276
Query: 562 QQ--------PAPAPAPLGTPVKQENSFSSCQLSQQ--PLGPAHPFNPSLAAPATNHIDP 611
QQ AP PA + E S S SQQ LG A P L P
Sbjct: 3277 QQQQQQHSLLSAPGPAQ-AMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQP------- 3328
Query: 612 CAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTV 671
+ P P Q+ L P ++ QG L + + VL+
Sbjct: 3329 --LMPTQPPAHALQQRLAPS-------MAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQ 3379
Query: 672 TNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMD---LEHPLQPLFGTPTSLLKKEPPGY 728
P + Q Q + + P +D E + P+ LK G
Sbjct: 3380 KPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALK----GI 3435
Query: 729 EEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLA 788
++ M+Q G + QQ+ L L SG S+D + + ++ S G P
Sbjct: 3436 KKVMAQGSIGVAPGMNRQQVSLLAQRL--SGGPSSDLQNHVAAGSGQERS----AGDPSQ 3489
Query: 789 AQPSP 793
+P+P
Sbjct: 3490 PRPNP 3494
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 62.0 bits (149), Expect = 2e-09
Identities = 140/587 (23%), Positives = 201/587 (34%), Gaps = 109/587 (18%)
Query: 296 AGEALGSSGTPPVRSLSTTNSSSSSG-APGPCGLARQNSTSLTGKP-GALPANLDDMKVA 353
AG A +GTP + L+ SS P P + + T + KP G LP L +
Sbjct: 310 AGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPK 369
Query: 354 ELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILH--KAGEVVV--A 409
P T T Q + +P PKAP + + KAG+ VV
Sbjct: 370 PFA--------PAGATLT--------IQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSG 413
Query: 410 FPAARLSTG----PALVAAGLAPAEV--VVATVASSGVVKFGSTGSTPPVSPTPSERSLL 463
FPA L P G AP + ++ S ++ GS+ P P + L
Sbjct: 414 FPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFL 473
Query: 464 STGDE--------NSTPGDTFGEMVTS--PLTQLTLQASPLQILVKEEGPRAGSCCLSPG 513
G ++ P + G+++ + P T L A+P+ GP + L+P
Sbjct: 474 LPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPH 533
Query: 514 GRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPA-PLG 572
G +L Q+ Q + ++ + L Q PAPA P
Sbjct: 534 S-----GAHSAHILSAAPIQVG---------QPALFQMPVSLAAGSLPTQSQPAPAGPAA 579
Query: 573 TPVKQENSF--SSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQP 630
T V Q + S+ + P G P P+ A + AP P V P
Sbjct: 580 TTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVST-----P 634
Query: 631 EPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSP---- 686
P + PQ PQ P+ + APP T SPGL+S
Sbjct: 635 LPLGLQQPQAQQPPQAPTP-QAAAPPQATTPQP--------------SPGLASSPEKIVL 679
Query: 687 -QQPSSQPGSPAPAPSAQMDL--EHPLQPL------FGTPTSLLKKEPPGYEEAMSQQPK 737
Q PS+ P + S QM L E QPL P S++ PP ++ P
Sbjct: 680 GQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV 739
Query: 738 QQENGSSSQQMDDLFDIL-IQSGEISADFKEP-----PSLPGKEKPSPKTVCGSPLAAQP 791
+ G Q D +A K P PSLP + SP +P
Sbjct: 740 AKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
Query: 792 S------------PSAELP-QAAPPPPGSPSLPGRLEDFLESSTGLP 825
P +E P PPP P+LPG +++ G+P
Sbjct: 800 PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF--VIQNQLGVP 844
Score = 46.2 bits (108), Expect = 1e-04
Identities = 99/495 (20%), Positives = 155/495 (31%), Gaps = 83/495 (16%)
Query: 390 APKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGS 449
AP PAAT++L G + A L+T LV PA AT ++ V+
Sbjct: 573 APAGPAATTVLQ--GVTLPPSAVAMLNTPDGLVQ----PATPAAATGEAAPVLTVQPAPQ 626
Query: 450 TPPVSPTPSERSLLSTGDENS----TPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRA 505
PP TP L + TP T+P L +SP +I++ +
Sbjct: 627 APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSAT 686
Query: 506 GSCCLSPGGRAELEGRDKDQM-LQEKDKQIEALTRML----------RQKQQLVERLKLQ 554
+ L+ +++ Q L + + ++ + + L
Sbjct: 687 PTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLG 746
Query: 555 LEQEKRAQQPAPAPA-PLGTPVKQENSFSSCQLSQQ-PLG-------------------- 592
+ PAPAP P P+K SS L Q PLG
Sbjct: 747 PQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR 806
Query: 593 -----------PAHPFNPSLAAPATNHI--------------DPCAVAPGPPSVVVKQEA 627
P HP P A P I +P APGPP ++ ++
Sbjct: 807 PQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS 866
Query: 628 LQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQ 687
PE PAP L ++ + + T + L +
Sbjct: 867 QPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTL 926
Query: 688 QPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKK---EPPG--YEEAMSQQPKQQENG 742
+P +P P P + P P +LL++ P G + P +
Sbjct: 927 HLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS 986
Query: 743 SSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSP--------LAAQPSPS 794
+S + ++ SG+ + PS P+P G P A P+
Sbjct: 987 TSLGPLTSPAASVLVSGQAPSGTPTAPS--HAPAPAPMAATGLPPLLPAENKAFASNLPT 1044
Query: 795 AELPQAAPPPPGSPS 809
+ +AA PG PS
Sbjct: 1045 LNVAKAASSGPGKPS 1059
Score = 41.6 bits (96), Expect = 0.003
Identities = 126/535 (23%), Positives = 180/535 (33%), Gaps = 102/535 (19%)
Query: 411 PAARLSTGPALVAAGLAPAEVVVATVASS--GVVKFGSTGSTPPVSPTPSERSLLSTGDE 468
P S G + AGL + + A VA++ G FG G+ + TPS + L
Sbjct: 272 PVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGL 331
Query: 469 NSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEG---PRAGSCC---LSPGGRAELEGRD 522
S+P P + L +P I K G P+ +P G A L +
Sbjct: 332 GSSP--------LVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAG-ATLTIQG 382
Query: 523 KDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFS 582
+ L ++ K + LT M K + PAPA KQ + +
Sbjct: 383 EPGALPQQPKAPQNLTFMAAGKAG-----------QNVVLSGFPAPALQANVFKQPPATT 431
Query: 583 SCQLSQQPLGPAHPFNPSLAAPATNHI---DPCAVAPGPPSVVVKQEALQPEPEPVPAPQ 639
+ QP G +L+ P + H+ V P + + + L P V PQ
Sbjct: 432 TGAAPPQPPG-------ALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
Query: 640 LLLGPQ---GPSLIKGVAPPTLITDSTGTHLVLT--VTNKNADSPGLSSGSPQQPSSQPG 694
L G ++ AP TG L+ +TN+N P LS G P S
Sbjct: 485 QLSALPANVGGQILAAAAP------HTGGQLIANPILTNQNLAGP-LSLGPVLAPHSGAH 537
Query: 695 SPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQEN------GSSSQQM 748
S +A + + P LF P SL P + P S+ M
Sbjct: 538 SAHILSAAPIQVGQPA--LFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAM 595
Query: 749 DDLFDILIQSGEISADFKEP-PSLPGKEKPSPKTVCGSPLA-------AQPSPSAELPQA 800
+ D L+Q +A E P L + P +PL AQ P A PQA
Sbjct: 596 LNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQA 655
Query: 801 APPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSP 860
A PP + P S GL PE + +L PPS
Sbjct: 656 AAPPQATTPQP---------SPGLA------SSPEKI---------------VLGQPPSA 685
Query: 861 MDTSEL------HFVPEPSSTMGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTA 909
T+ L F+P+ S L HL + +S+ P AP + A
Sbjct: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA 740
Score = 33.9 bits (76), Expect = 0.72
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 148 PLLSATSA--SPTQVVSQLPMGRDSREMLFLAEQPPLPPPP--LLPPSLTNGTTIPTAKS 203
P+L+ A +P V + LP+G + A+QPP P P PP T P S
Sbjct: 617 PVLTVQPAPQAPPAVSTPLPLGLQQPQ----AQQPPQAPTPQAAAPPQATTPQPSPGLAS 672
Query: 204 TPTLIKQSQPKSAS 217
+P I QP SA+
Sbjct: 673 SPEKIVLGQPPSAT 686
Score = 33.1 bits (74), Expect = 1.2
Identities = 54/204 (26%), Positives = 75/204 (36%), Gaps = 53/204 (25%)
Query: 620 SVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTH------------- 666
S VV AL P +P P P L + P PPT + T H
Sbjct: 1319 SKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGT 1378
Query: 667 ------LVLTVT-NKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTS 719
L L T +N PG G+P ++ GSPAP P A++D TS
Sbjct: 1379 APHCPRLPLRKTYRENVGGPGAPEGTP-AGRARGGSPAPLP-AKVD----------EATS 1426
Query: 720 LLKKEPPGYEEAMSQQ----PKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKE 775
L +E E+ + Q+ P + S++Q D D++ P P K
Sbjct: 1427 GLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGD------------PDWEAPGLPPAKR 1474
Query: 776 KPSPKTVCGSPLAAQPSPSAELPQ 799
+ S SP Q S S++ PQ
Sbjct: 1475 RKSE-----SPDVDQASFSSDSPQ 1493
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 62.0 bits (149), Expect = 2e-09
Identities = 87/384 (22%), Positives = 137/384 (35%), Gaps = 70/384 (18%)
Query: 558 EKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPG 617
E A P AP + +P+ +S S P+ + P LA+P ++ + +
Sbjct: 1384 EVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSP----LASPVSSTVSVPLSSSL 1439
Query: 618 PPSV--VVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKN 675
P SV + A P P+ AP L + GP+L+ V PP
Sbjct: 1440 PISVPTTLPAPASAPLTIPISAP-LTVSASGPALLTSVTPPL------------------ 1480
Query: 676 ADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQ 735
+P P++ PG P+ APS L T SL + PG+ ++
Sbjct: 1481 ---------APVVPAA-PGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPT 1530
Query: 736 PKQQENGSSSQQMDDLFDILIQSGEISADFKEPPS-LPGKEK-----PSPKTVCGSPLAA 789
G +S +L+ + +++ F P+ P + S +PLA
Sbjct: 1531 SSHVP-GLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589
Query: 790 QPSPSAELPQAAPPPPGSP-----SLPGRLEDFLESSTGLPL----------LTSGHDGP 834
+P + +P PP +P PG S T +P+ L S P
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVP 1649
Query: 835 EPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMDWLELS 894
P ++ +Q + + PSP T L P + T+G G S L L
Sbjct: 1650 APTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLG-----GSSPSQT-LSLG 1703
Query: 895 SGGP-------VLSLAPLSTTAPS 911
+G P LSL P S+ P+
Sbjct: 1704 TGNPQGPFPTQTLSLTPASSLVPT 1727
Score = 55.1 bits (131), Expect = 3e-07
Identities = 185/846 (21%), Positives = 276/846 (32%), Gaps = 141/846 (16%)
Query: 123 LSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPP- 181
L P QP S +PSPL +LS TS PT +S P + L+ PP
Sbjct: 1072 LPPLQPNSGSLPQVLPSPLG------VLSGTSRPPTPTLSLKPT---PPAPVRLSPAPPP 1122
Query: 182 ----------LPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKP 231
+PP PP+ T+ TA +T T + P A ++ S + P
Sbjct: 1123 GSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAV--PAPTPAPQRLILSPDMQARLP 1180
Query: 232 KVKKLKYHQYIPPDQK---QDRGAPPM------------DSSYAKILQQQQLFLQLQILN 276
+ + Q Q+ G+ P+ + ++ Q LQ +++
Sbjct: 1181 SGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVH 1240
Query: 277 --QQQQQHHNYQAILPAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGL-----A 329
QHH L + P + TP +S SS+ S P P GL A
Sbjct: 1241 LVSAGGQHH-----LISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAA 1295
Query: 330 RQNSTSLTGKPGALPANLDDMKVAELKQELKLRSL---PVSGTKTELIERLRAYQDQI-S 385
Q ++ G + + L L P SG L R ++ +
Sbjct: 1296 NQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPT 1355
Query: 386 PVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEV-----VVATVASSG 440
P G +AP T L + +V P+ +S A G AP + V +++
Sbjct: 1356 PTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS----APGAAPLTISSPLHVPSSLPGPA 1411
Query: 441 VVKFGSTGSTPPVSPTPSERSL-LSTGDENSTPGDTFGEMVTSPLT-----QLTLQASPL 494
S+P SP S S+ LS+ S P T ++PLT LT+ AS
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVP-TTLPAPASAPLTIPISAPLTVSASGP 1470
Query: 495 QILVKEEGPRAGSCCLSPG------------------GRAELEGRDKDQ------MLQEK 530
+L P A +PG G A Q +L
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPT 1530
Query: 531 DKQIEALTRMLRQK-QQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQ 589
+ L + ++ A PAPA A L P S+ Q
Sbjct: 1531 SSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPAS-----SASQALAT 1585
Query: 590 PLGP-AHPFNPSLAAPATNHIDPCAV-APGPPSVVVKQEALQPEP--------------- 632
PL P A P LA + P V AP P + V + P P
Sbjct: 1586 PLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA 1645
Query: 633 EPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSS- 691
PVPAP +L P + P+ + T T+ A +P L SP Q S
Sbjct: 1646 SPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQ---TLALAPALAPTLGGSSPSQTLSL 1702
Query: 692 ---QPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQM 748
P P P + + L P SL P G + +S P +S
Sbjct: 1703 GTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGP 1762
Query: 749 DDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSP 808
+ + SA P S+ T+ +P+ +A+ AP SP
Sbjct: 1763 APAHTLTLAPASSSASLLAPASV------QTLTLSPAPVPTLGPAAAQTLALAPASTQSP 1816
Query: 809 SLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDL--HSQMLSSTAILDHPPSPMDTSEL 866
+ ++ L + SG P P++++ L + + PPSP T+
Sbjct: 1817 A---------SQASSLVVSASG-AAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATS 1866
Query: 867 HFVPEP 872
P P
Sbjct: 1867 FGGPRP 1872
Score = 52.0 bits (123), Expect = 3e-06
Identities = 161/698 (23%), Positives = 239/698 (34%), Gaps = 115/698 (16%)
Query: 123 LSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPPL 182
L P++ + + PL A P + + VV Q P RD L PPL
Sbjct: 1275 LPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAP--RDG-----LTPVPPL 1327
Query: 183 PPPPLLP-----------PSLTNGT----TIPTAKS---TPTLIKQSQPKSASEKSQRSK 224
P P P P+LT G T+ TA++ TPTL++ S + S
Sbjct: 1328 APAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSA 1387
Query: 225 KAKELKPKVKKLKYH--QYIP-------PDQKQDRGAPPMDSSYAKILQQQQLFLQLQIL 275
A P H +P P A P+ S+ + L L
Sbjct: 1388 SAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTL 1447
Query: 276 NQQQQQHHNYQAILPAPPKSAGEALGSSGTPPVR----------SLSTTNSSSSSGAPGP 325
P ++G AL +S TPP+ SL+ + +S S+ A
Sbjct: 1448 PAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASAL-T 1506
Query: 326 CGLARQNSTSLTGKPG-ALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQI 384
GLA S S + PG L V L + PV + L
Sbjct: 1507 LGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALA---------- 1556
Query: 385 SPVPGAPK-APAATSILHKAGEV--VVAFPAARLSTGP-ALVAAGLAPAEVVVATVASS- 439
SP P AP APA S+L A +A P A ++ A++A AP + +A S
Sbjct: 1557 SPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSP 1616
Query: 440 GVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVK 499
G ++ TP PS S + P T V +P + T+ +P+ +
Sbjct: 1617 GAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPT---PVLAPSSTQTMLPAPVPSPLP 1673
Query: 500 EEGPRAGSCCLSPGGRAELEGRDKDQMLQ----EKDKQIEALTRMLRQKQQLVERLKLQL 555
+ L+P L G Q L T L LV
Sbjct: 1674 SPASTQ-TLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPT----- 1727
Query: 556 EQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLA-----APATNHID 610
AQ + AP P P+ + S PL PA P P+ A APA++
Sbjct: 1728 ----PAQTLSLAPGP---PLGPTQTLSLAPAP--PLAPASPVGPAPAHTLTLAPASSSAS 1778
Query: 611 PCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLT 670
+AP + A P P A L L P A +++ S L +T
Sbjct: 1779 --LLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVT 1836
Query: 671 VTNK------NADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKE 724
+ ++ D+ L SG P PS+ P P Q P P P S
Sbjct: 1837 MVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQ-----PPPP----PRS----- 1882
Query: 725 PPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEIS 762
P Y +++ ++ K+Q S++++ +F + G ++
Sbjct: 1883 -PFYLDSLEEKRKRQR----SERLERIFQLSEAHGALA 1915
Score = 49.3 bits (116), Expect = 2e-05
Identities = 140/606 (23%), Positives = 211/606 (34%), Gaps = 94/606 (15%)
Query: 351 KVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAF 410
K ++K L+ +P +T ++ + + + PVP P S G V
Sbjct: 988 KPVKMKVNRMLQPVPKQEGRTVVV--VNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVL 1045
Query: 411 PAARLST----GPALVAAGLAPAEVVVATVASS------------GVVKFGSTGSTPPVS 454
PA+ + + GP L+ A P V++ + + GV+ S TP +S
Sbjct: 1046 PASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLS 1105
Query: 455 --PTPSERSLLSTGDENST----------PGDTFGEMVTSPLTQLTLQASPLQILVKEEG 502
PTP LS + PG TF + + T A+ +
Sbjct: 1106 LKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPA 1165
Query: 503 PRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQL--VERLKLQLEQEKR 560
P+ LSP +A L + + Q + K ++ KL L +
Sbjct: 1166 PQR--LILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQV 1223
Query: 561 AQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPS 620
Q P PL Q N Q + P + +L I A PGP
Sbjct: 1224 RQLAVGQPRPL-----QRNVVHLVSAGGQHHLISQPAHVAL-------IQAVAPTPGPTP 1271
Query: 621 VVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPG 680
V V + P PAP L P L PPT++ ++TG V+ + + A G
Sbjct: 1272 VSVLPSST---PSTTPAPTGLSLP----LAANQVPPTMV-NNTG---VVKIVVRQAPRDG 1320
Query: 681 LSSGSPQQPSSQPGSPA-PA---PSAQMDLEHPLQPLFGT-----PTSLLKKEPPGYEEA 731
L+ P P+ +P S PA P + P GT PT L + P +
Sbjct: 1321 LTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVR--PLLKLV 1378
Query: 732 MSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQP 791
S P+ + + + IS+ P SLPG SPLA+
Sbjct: 1379 HSPSPEVSASAPGAAPLT-----------ISSPLHVPSSLPGPASSPMPIPNSSPLASPV 1427
Query: 792 SPSAELPQAAPPPPGSP-SLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSS 850
S + +P ++ P P +LP L PL S GP L+ +
Sbjct: 1428 SSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSA-SGPALLTSVTP------PL 1480
Query: 851 TAILDHPPSPMDTSELHFVPEPSS-TMGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTA 909
++ P P + P S+ T+GL A S + G P+L LAP S+
Sbjct: 1481 APVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ-----TPGHPLL-LAPTSSHV 1534
Query: 910 PSLFST 915
P L ST
Sbjct: 1535 PGLNST 1540
Score = 40.4 bits (93), Expect = 0.008
Identities = 101/470 (21%), Positives = 150/470 (31%), Gaps = 85/470 (18%)
Query: 136 SVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPPLPPPPLLPPSLTNG 195
S P+P A+ S L A+SAS PM +L + PPL P P+L PS
Sbjct: 1561 SAPNPAPAQASL-LAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPS---P 1616
Query: 196 TTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPM 255
P S+ T + P S S S V + P Q P+
Sbjct: 1617 GAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPV--------LAPSSTQTMLPAPV 1668
Query: 256 DSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEALGSSGTPPVRSLSTTN 315
S LP+P + AL + P + S+ +
Sbjct: 1669 PSP------------------------------LPSPASTQTLALAPALAPTLGG-SSPS 1697
Query: 316 SSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIE 375
+ S G P G + SLT +P + +A P+ T+T
Sbjct: 1698 QTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP--------GPPLGPTQT---- 1745
Query: 376 RLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAG-LAPAEVVVA 434
+S P P APA+ V PA L+ PA +A LAPA V
Sbjct: 1746 --------LSLAPAPPLAPASP---------VGPAPAHTLTLAPASSSASLLAPASVQTL 1788
Query: 435 TVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPL 494
T++ + V G + S +S S + + +++L +
Sbjct: 1789 TLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEP 1848
Query: 495 QILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQ 554
L GP SP A G + + + L +K R + +
Sbjct: 1849 DTLTLRSGPP------SPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEK-----RKRQR 1897
Query: 555 LEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAP 604
E+ +R Q + A L PV C L Q P P +P + P
Sbjct: 1898 SERLERIFQLSEAHGAL-APVYGTEVLDFCTLPQPVASPIGPRSPGPSHP 1946
Score = 35.4 bits (80), Expect = 0.25
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 2/101 (1%)
Query: 771 LPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSG 830
LP PS C SP A P P+ P A PPP L L +P+ S
Sbjct: 2482 LPSPPPPSQIPPCSSP-ACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASV 2540
Query: 831 HDGPEPLSLIDDLHSQMLSSTAILD-HPPSPMDTSELHFVP 870
+ P L +L +Q L+S L+ + +TS L VP
Sbjct: 2541 TNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVP 2581
Score = 34.3 bits (77), Expect = 0.55
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 15/114 (13%)
Query: 606 TNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGT 665
TN DP PGP +++V L+P+ P P P LGPQ P L++
Sbjct: 2889 TNGADP---VPGPETLIVADPVLEPQLIPGPQP---LGPQPVH-----RPNPLLSPVEKR 2937
Query: 666 HLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTS 719
++ PG S + S P P PS PL PL PT+
Sbjct: 2938 RRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLT----PLPPLLVCPTA 2987
Score = 33.1 bits (74), Expect = 1.2
Identities = 48/229 (20%), Positives = 86/229 (37%), Gaps = 30/229 (13%)
Query: 122 ALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPP 181
+L+P P+ GS+P+ E + T ++ LP G + + +
Sbjct: 2601 SLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTT-------LTVLPEGEELPLCVSESNGLE 2653
Query: 182 LPPP-----PLLPP--------SLTNGTTIPTAKSTPTLIKQSQ---PKSASEKSQRSKK 225
LPP PL P LT T ++ P + ++ P ++S + +
Sbjct: 2654 LPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEG 2713
Query: 226 AKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQ-LQILNQQQQQHHN 284
+P ++ I G PP K+ + ++ +++ +++QQ
Sbjct: 2714 PSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGA 2773
Query: 285 YQAILPAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNS 333
++P E S G+P VRS+S SS G GPC A +S
Sbjct: 2774 ASTLVPG----VSETSASPGSPSVRSMSGPESSPPIG--GPCEAAPSSS 2816
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 61.2 bits (147), Expect = 4e-09
Identities = 73/312 (23%), Positives = 123/312 (39%), Gaps = 44/312 (14%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPA-------HPFNPSLAAPATNH-IDPCA 613
++P A + TP + + ++ ++P PA P +P+ A P P A
Sbjct: 1050 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109
Query: 614 VAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTN 673
P P A+ EP + P+ P+ AP + + + V T
Sbjct: 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF---PAPAVPTPEESASAAVAVPTP 1166
Query: 674 KNADSPGLSSGSPQQPSS---------QPGSPA---PAPSAQM-DLEHPLQPLFGTPTSL 720
+ + SP + +P + +S +P SPA P P+A + LE P PTS
Sbjct: 1167 EESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS- 1225
Query: 721 LKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFD---ILIQSGEISADFKEPPSLPGKEKP 777
+EP A+S + ++ +++ ++ E+S+ S+P E+P
Sbjct: 1226 --EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP---AASVPTPEEP 1280
Query: 778 SPKTVC-------GSPLAAQPSPS-AELPQAAPPPPGSPSLPGRLEDFLE--SSTGLPLL 827
+ SP AA P+P A +P A+ P P P++P +E S G+P L
Sbjct: 1281 ASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFL 1340
Query: 828 -TSGHDGPEPLS 838
S H P+S
Sbjct: 1341 GVSAHTDSVPIS 1352
Score = 48.5 bits (114), Expect = 3e-05
Identities = 69/334 (20%), Positives = 118/334 (35%), Gaps = 41/334 (12%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPA-------HPFNPSLAAPATNH-IDPCA 613
++PA A + TP + + ++ ++P PA P +P+ A P P A
Sbjct: 998 EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA 1057
Query: 614 VAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTN 673
P P A+ EP + P+ P+ P + + T
Sbjct: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTP 1114
Query: 674 KNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMS 733
+ SP + +P++P+S P + P P E P P PT P A
Sbjct: 1115 EEPASPAAAVPTPEEPAS-PAAAVPTP------EEPAFPAPAVPT------PEESASAAV 1161
Query: 734 QQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSP 793
P +E+ S + + + + ++ E P+ P P+P + + L SP
Sbjct: 1162 AVPTPEESASPAAAVPTPAESASFAAVVAT--LEEPTSPAASVPTPAAMVAT-LEEFTSP 1218
Query: 794 SAELPQAAPPP--------PGSPSLPGRLEDFLE---SSTGLPLLTSGHDGPEPLSLIDD 842
+A +P + P P P+ P LE SS L P +
Sbjct: 1219 AASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPE 1278
Query: 843 LHSQMLSSTAILDHPPSP---MDTSELHFVPEPS 873
+ ++ + L+ P SP + T E+ +P S
Sbjct: 1279 EPASPAAAVSNLEEPASPAAAVPTPEVAAIPAAS 1312
Score = 47.8 bits (112), Expect = 5e-05
Identities = 63/287 (21%), Positives = 100/287 (34%), Gaps = 55/287 (19%)
Query: 593 PAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLG-PQGPSLIK 651
P P P+ A D AV P A P PE +P + P+ P+
Sbjct: 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030
Query: 652 GVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQ 711
PP + SP + +P++P+S P + P P E P
Sbjct: 1031 AAVPPP----------------EEPTSPAAAVPTPEEPTS-PAAAVPTP------EEPTS 1067
Query: 712 PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSL 771
P PT E P A P++ + +++ E P+
Sbjct: 1068 PAAAVPTP----EEPTSPAAAVPTPEEPTSPAAA-----------------VPTPEEPTS 1106
Query: 772 PGKEKPSPKTVCGSPLAAQPSPSAEL-PQAAPPPPGSPSLPG-RLEDFLESSTGLPLLTS 829
P P+P+ SP AA P+P P AA P P P+ P + ES++ + +
Sbjct: 1107 PAAAVPTPEEPA-SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPT 1165
Query: 830 GHDGPEPLSLIDD--LHSQMLSSTAILDHPPSPMDTSELHFVPEPSS 874
+ P + + + + A L+ P SP + VP P++
Sbjct: 1166 PEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS-----VPTPAA 1207
Score = 38.1 bits (87), Expect = 0.038
Identities = 56/261 (21%), Positives = 91/261 (34%), Gaps = 34/261 (13%)
Query: 613 AVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVT 672
A+ P P ++ + E E V A + P+ + P ++ GT V V+
Sbjct: 874 ALVPFPHEDILVASIVSLEEEDVTAAAVS-APE-----RATVPAVTVSVPEGTAAVAAVS 927
Query: 673 NKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAM 732
+ +P +++ Q+ S +P +A + + P+ GTP E P
Sbjct: 928 SPEETAPAVAAAITQEGMSAVAGFSPEWAA-LAITVPITEEDGTP------EGPVTPATT 980
Query: 733 SQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPS 792
P++ + + + E P+ P P+P+ SP AA P+
Sbjct: 981 VHAPEEPDTAA-----------------VRVSTPEEPASPAAAVPTPEEPT-SPAAAVPT 1022
Query: 793 PSAEL-PQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSST 851
P P AA PPP P+ P E T + P + + S
Sbjct: 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
Query: 852 AILDHPPSPMDTSELHFVPEP 872
A + P P TS VP P
Sbjct: 1083 AAVPTPEEP--TSPAAAVPTP 1101
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 60.5 bits (145), Expect = 7e-09
Identities = 144/640 (22%), Positives = 195/640 (30%), Gaps = 132/640 (20%)
Query: 385 SPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKF 444
SP P P PAA +L AG V P AG + + +G +
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAV---------GRKPLAERAGGIGGATIPESAPRAGPTRS 82
Query: 445 GSTGSTPPVS-PTPSERSLLSTGDEN------STPGDTFGEMVTSPLTQLTLQASPLQIL 497
T S P S P S R + +N S+PG G PL Q L+ S + +
Sbjct: 83 AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 142
Query: 498 VKEEGPRAGS-CCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVE------- 549
+ + A LS G R + G ++ A + +
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 550 ---RLKLQLEQEKRAQQPAPAP-------APLGTPVKQENSFSSCQLSQQ---------- 589
R + E +P+PA L P + S S+ LS
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 590 PLGPAHPFNPSL-----------------AAPATNHIDPCAVAPGPPSVVVKQEALQPEP 632
P PAHP P AAPA + +A PS ++ +A P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
Query: 633 EP-----------VPAPQLLLGPQGPSLIKGV-----APPTLITDSTGTHLVLTVTNKNA 676
P P P P ++ + PP+ T S G+ L T+
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP-TLQATHSFL 381
Query: 677 DSPGLS------------------SGSPQQPSSQPGSPAPAPSAQMD-------LEHPLQ 711
SP LS P P+S P SP PS Q L+ P
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 712 PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSL 771
P P P + S P Q S + + + P S
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPS------------LAAPPLQVPPSPPASP 489
Query: 772 PGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGH 831
P +P PLAA P A+ P APP +P L P S
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549
Query: 832 DGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMDWL 891
PL+ +L++ +L PPSP + L P T G D
Sbjct: 550 LPMSPLATPPPQAPPVLAA-PLLQVPPSPPASPTLQ-APRRPPTPGPD------------ 595
Query: 892 ELSSGGP--VLSLAPLSTTAPSLFSTDFLDGHDLQLHWDS 929
S GP L+LAP PS + L G DL H S
Sbjct: 596 -TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
Score = 49.3 bits (116), Expect = 2e-05
Identities = 130/567 (22%), Positives = 189/567 (33%), Gaps = 104/567 (18%)
Query: 289 LPAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLD 348
LP P SA + G P +S+S+ + S++ P P R ++ +P + +
Sbjct: 189 LPRPAPSARPRPPTEG--PRKSVSSASEHSTT-EPSPAARRRPSAGGGLQRPASRSLS-- 243
Query: 349 DMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVP-GAPKAPAATSILHKAGEVV 407
L S SG R A+ Q P A + P T A +
Sbjct: 244 -------SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 408 VAFPAARLST-GPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTG 466
++ L+T P+ AP + +SS + + P SP+ + SL +
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS-APPSLQTLP 355
Query: 467 DENSTPGDTFGEMVTSPLTQLT---LQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDK 523
+TP + SP Q T L + PL L + L P
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP----------- 404
Query: 524 DQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAP-APAPLGTPVKQENSFS 582
L+ + Q L + L Q + P+P AP P S S
Sbjct: 405 -LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Query: 583 SCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPE---PVPAPQ 639
+ SQ P PSLAAP P V P PP+ + P P+ P+ AP
Sbjct: 464 ATPPSQAP--------PSLAAP------PLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 640 LLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGL-----SSGSPQQPSSQPG 694
L L P APP L T + + + A PG S+ P P + P
Sbjct: 510 LQLAKPPPQ-----APPALATPP-----LQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
Query: 695 SPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPP--GYEEAMS-----------QQPKQQEN 741
AP A L+ P P +PT + PP G + ++S P +
Sbjct: 560 PQAPPVLAAPLLQVPPSPP-ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Query: 742 GSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEK---------PSPKTVCGS------- 785
SS+ DL +G S+ P L G + P P +
Sbjct: 619 PSSTLSGPDL------AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672
Query: 786 -----PLAAQPSPSAELPQAAPPPPGS 807
PLA + +P A LP PGS
Sbjct: 673 RGPAPPLAFRGAPGAPLPWPPATGPGS 699
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 60.1 bits (144), Expect = 9e-09
Identities = 134/574 (23%), Positives = 184/574 (32%), Gaps = 86/574 (14%)
Query: 390 APKA-PAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGV-VKFGST 447
AP+A P TS +G A PA S GP + + G A + G+ + T
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGP-VSSPGRASGTTRPGPLGQKGLRISAEET 132
Query: 448 GSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGS 507
+ + P +RS LS G T G T G SP +A+ ++ + P A
Sbjct: 133 VARGKATEAP-KRSALSAGARRDTSGPTPG--TPSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 508 CCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPA 567
R EG K + E + R++ L Q ++ + +
Sbjct: 190 -------RPPTEGPRKSVSSASEHSTTEP-SPAARRRPSAGGGL-----QRPASRSLSSS 236
Query: 568 PAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEA 627
PL +P + S P PAHP P + P V P
Sbjct: 237 ATPLSSPARSGPSARGT-----PRAPAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGP 289
Query: 628 LQPEPEPVPAPQLLLGPQGPSLIKGV-----APPTLITDSTGTHLVLTVTNKNADSPGLS 682
L P P+P P P ++ + PP+ T S G+ L T+ SP LS
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP-TLQATHSFLPSPPLS 348
Query: 683 ------------------SGSPQQPSSQPGSPAPAPSAQMD-------LEHPLQPLFGTP 717
P P+S P SP PS Q L+ P P P
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 718 TSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKP 777
P + S P Q S + + + P S P
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPS------------LAAPPLQVPPSPPASPPMSPSA 456
Query: 778 SPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPL 837
+P PLAA P A+ P APP +P L P S PL
Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 838 SLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMDWLELSSGG 897
+ +L++ +L PPSP + L P T G D S G
Sbjct: 517 ATPPPQAPPVLAA-PLLQVPPSPPASPTLQ-APRRPPTPGPD-------------TSVSG 561
Query: 898 P--VLSLAPLSTTAPSLFSTDFLDGHDLQLHWDS 929
P L+LAP PS + L G DL H S
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595
Score = 48.9 bits (115), Expect = 2e-05
Identities = 135/604 (22%), Positives = 188/604 (31%), Gaps = 131/604 (21%)
Query: 290 PAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPC-----------GLARQNSTSLTG 338
P P S G A G++ P+ S+ + A G G R S G
Sbjct: 102 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161
Query: 339 KPGALPANLDDMKVAELKQELKLRSL----PVSGTKTELIERLRAYQDQISPVPGAPKAP 394
P A E+ S P G + + + P P A + P
Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA--SEHSTTEPSPAARRRP 219
Query: 395 AATSILHKAGEVVVAFPAARLST----GPALVAAGLAPAEVV--------------VATV 436
+A L + ++ A LS+ GP+ APA V
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 279
Query: 437 ASSGVVKFGSTGSTPPVSPTPSER-------SLLSTGDENSTPGDTFGEMVTSPLTQLT- 488
G S+P +P+PS SL + +TP + SP Q T
Sbjct: 280 RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339
Query: 489 --LQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQ 546
L + PL L + L P L+ + Q
Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALPP------------LQAPPSPPASPPLSPLATPSPQ 387
Query: 547 LVERLKLQLEQEKRAQQPAP-APAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPA 605
L + L Q + P+P AP P S S+ SQ P PSLAAP
Sbjct: 388 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--------PSLAAP- 438
Query: 606 TNHIDPCAVAPGPPSVVVKQEALQPEPE---PVPAPQLLLGPQGPSLIKGVAPPTLITDS 662
P V P PP+ + P P+ P+ AP L L P APP L T
Sbjct: 439 -----PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ-----APPALATPP 488
Query: 663 TGTHLVLTVTNKNADSPGL-----SSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTP 717
+ + + A PG S+ P P + P AP A L+ P P +P
Sbjct: 489 -----LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP-ASP 542
Query: 718 TSLLKKEPP--GYEEAMS-----------QQPKQQENGSSSQQMDDLFDILIQSGEISAD 764
T + PP G + ++S P + SS+ DL +G S+
Sbjct: 543 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL------AGHSSSA 596
Query: 765 FKEPPSLPGKEK---------PSPKTVCGS------------PLAAQPSPSAELPQAAPP 803
P L G + P P + PLA + +P A LP
Sbjct: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656
Query: 804 PPGS 807
PGS
Sbjct: 657 GPGS 660
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 60.1 bits (144), Expect = 9e-09
Identities = 156/691 (22%), Positives = 236/691 (34%), Gaps = 142/691 (20%)
Query: 189 PPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQ 248
PP +G P+ ST +S+ + S RS ++LK
Sbjct: 454 PPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLK------------------ 495
Query: 249 DRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAG-EALGSSGTPP 307
R PP +++ L Q+ L + L + Q LP PP + G E G++ PP
Sbjct: 496 -RPPPPPRRTHS--LHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPP 552
Query: 308 ------VRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELKL 361
V LS S +P +S +G P P L + K +
Sbjct: 553 NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ--- 609
Query: 362 RSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPAL 421
K E + LR+ PGA + + TS+ + + PA +GP +
Sbjct: 610 ------PPKPERVTSLRS--------PGASVSSSLTSLCSSSSD-----PAPSDRSGPQI 650
Query: 422 VAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVT 481
L P V S + P SP P+ +L + T +
Sbjct: 651 ----LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQS 706
Query: 482 SPLTQLTLQASPLQ---ILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALT 538
P Q TL +PLQ ++ K++ P P K +++ E E
Sbjct: 707 PPTPQTTL--TPLQESPVISKDQSPPPSP---PPSYHPPPPPTKKPEVVVEAPSASETAE 761
Query: 539 RMLRQ-----------KQQLVERLKLQLEQEKRAQQPAPAPA-PLGTPV----KQENSFS 582
L+ ++Q + +E +P PA P G+P +S S
Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS 821
Query: 583 SCQLSQQPLG----PAHPFNPSLAAPATNHI------DP--CAVAPGPPSVVVKQEALQP 630
+ L QP G P P P+ A+ A H+ +P C+ GPP V + P
Sbjct: 822 ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881
Query: 631 E----------PEPVPAPQLLLGPQGPS-----LIKGVAPPTLITDSTGTHLVLTVTNKN 675
P AP LGP P + G A P + S+G H + + +
Sbjct: 882 SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASP-VPAPSSGLHAAVRLKACS 940
Query: 676 -ADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQ 734
A S GLSS P P P +P++ T + + K G + +
Sbjct: 941 LAASEGLSSAQPNGPPEAEPRPPQSPAS-------------TASFIFSK---GSRKLQLE 984
Query: 735 QPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPS 794
+P E + Q+ +++ + IS + PP P K SPK P P
Sbjct: 985 RPVSPETQADLQR-----NLVAELRSISE--QRPPQAP---KKSPKA---------PPPV 1025
Query: 795 AELPQAAPPPPGSPSLPGRLEDFLESSTGLP 825
A P PPP SPS P + GLP
Sbjct: 1026 ARKPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 89/247 (36%), Gaps = 51/247 (20%)
Query: 593 PAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGP--QGPSLI 650
P+ P +P+ AAPA + AV PGP S P+ P PQ L P + P +
Sbjct: 674 PSKPRSPNPAAPA---LAAPAVVPGPVSTT------DASPQSPPTPQTTLTPLQESPVIS 724
Query: 651 KGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPL 710
K +PP SP S P P+ +P APSA E PL
Sbjct: 725 KDQSPP--------------------PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPL 764
Query: 711 Q-PLFGTPTSLLKKE--------PPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEI 761
Q P + P +E PP E S + S S ++ + S
Sbjct: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPEL--VSSPAASSSSA 822
Query: 762 SADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESS 821
+A +P PG P P +P ++ P A+LPQ P P R
Sbjct: 823 TALQIQP---PGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPR------ED 873
Query: 822 TGLPLLT 828
G PL+T
Sbjct: 874 VGAPLVT 880
Score = 32.0 bits (71), Expect = 2.8
Identities = 88/411 (21%), Positives = 140/411 (34%), Gaps = 70/411 (17%)
Query: 106 YPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLP 165
+PKV S + +P PA + VP P+ + P + PT + P
Sbjct: 663 HPKVPAPFSPPPSKPRSPNPAAPAL-AAPAVVPGPVSTTDASP-----QSPPTPQTTLTP 716
Query: 166 MGRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKK 225
+ ++S + PP PPP PP P P ++ ++ SASE ++ +
Sbjct: 717 L-QESPVISKDQSPPPSPPPSYHPP--------PPPTKKPEVVVEA--PSASETAEEPLQ 765
Query: 226 AKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNY 285
P PP +++ D S A ++ F +
Sbjct: 766 DPNWPPP----------PPPAPEEQ-----DLSMADFPPPEEAFFSVASPEPAGPSGSPE 810
Query: 286 QAILPAPPKSAGEAL-----GSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKP 340
PA S+ AL GS PP + + +S APG Q K
Sbjct: 811 LVSSPAASSSSATALQIQPPGSPDPPP----APPAPAPASSAPGHVAKLPQKEPVGCSKG 866
Query: 341 GALPAN--LDDMKVAELKQELKLRSLPV-SGTKTELIERLRAYQDQISPVPGAPKAPAAT 397
G P + L Q ++LRS+ G T + P AP+ P
Sbjct: 867 GGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG------------PSAPQKPLRR 914
Query: 398 SILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTP 457
++ +A V P++ L L A LA +E + + + PP SP
Sbjct: 915 ALSGRASPVPA--PSSGLHAAVRLKACSLAASEGLSSAQPNGP----PEAEPRPPQSPAS 968
Query: 458 SERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQ---ASPLQILVKEEGPRA 505
+ + S G E SP TQ LQ + L+ + ++ P+A
Sbjct: 969 TASFIFSKGSRKLQL-----ERPVSPETQADLQRNLVAELRSISEQRPPQA 1014
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 57.4 bits (137), Expect = 6e-08
Identities = 81/325 (24%), Positives = 123/325 (37%), Gaps = 30/325 (9%)
Query: 567 APAPLGTPVKQ-ENSFSSCQLSQQPLGP----AHPFNPSLAAPATNHIDPCAVAPG---- 617
AP+ PV Q + S SSC ++ + P +H P L PA + P V
Sbjct: 783 APSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTP 842
Query: 618 ---PPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNK 674
PPS+ +Q P PVP P + P GP + + PP T + T +
Sbjct: 843 HHTPPSIGAQQPPATTIPAPVPTPPAM--PPGPQ-SQALHPPPRQTPTPPTTQLPQQVQP 899
Query: 675 NADSPGLSSGSPQQPSSQPGSPA--PAPSAQMDLEHPLQPLFGTPTSL--LKKEPPGYE- 729
+ + + QQP SQ + A P P+A + P PL S+ PP
Sbjct: 900 SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS 959
Query: 730 -EAMSQ-----QPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVC 783
E SQ QP Q+ + ++D Q +IS E + E T
Sbjct: 960 TEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTEL 1019
Query: 784 GSPL-AAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGH-DGPEPLSLID 841
+ + + PS Q++P P S + E+ ++ +P L + + PE L
Sbjct: 1020 KTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQAL--MPTLEALYRQDPESLPFRQ 1077
Query: 842 DLHSQMLSSTAILDHPPSPMDTSEL 866
+ Q+L D SPMD S +
Sbjct: 1078 PVDPQLLGIPDYFDIVKSPMDLSTI 1102
Score = 42.4 bits (98), Expect = 0.002
Identities = 76/331 (22%), Positives = 111/331 (33%), Gaps = 58/331 (17%)
Query: 523 KDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFS 582
+ Q LQ + +Q + MLR++ ++R + +Q+ P+P PA TP Q+ +
Sbjct: 1814 RQQQLQHRLQQAQ----MLRRRMASMQRTGVVGQQQGL---PSPTPATPTTPTGQQPTTP 1866
Query: 583 SCQLSQQPLGPAHPFNPSLAAPATNHIDPCA--------VAPGPPSVVVKQEALQPEPEP 634
P P + P T P + P PP Q A P P P
Sbjct: 1867 QTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPP-----QTAQPPLPGP 1921
Query: 635 VPAP---------------------------QLLLGPQGPSLIKGVAPPTLITDSTGTHL 667
PA Q + P P G+ PP + +G HL
Sbjct: 1922 PPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSG-HL 1980
Query: 668 V--LTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPL----QPLFGTPTSLL 721
+ T P G PQ Q G P PA + PL QP G
Sbjct: 1981 EPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISP 2040
Query: 722 KKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADF-KEPPSLPGKEKPSPK 780
K ++A+ + + SS Q + IL + ++ A F K+ + P P
Sbjct: 2041 LKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQP- 2099
Query: 781 TVCGSPLAAQPSPSAELPQAAPPPPGSPSLP 811
+ G P Q P + P P G S P
Sbjct: 2100 -IPGQPGMPQGQPGLQ-PPTMPGQQGVHSNP 2128
Score = 35.8 bits (81), Expect = 0.19
Identities = 66/307 (21%), Positives = 102/307 (33%), Gaps = 64/307 (20%)
Query: 102 GQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVV 161
GQ + SSS +S + P SH +P P + SP+ V
Sbjct: 787 GQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQP----------ALHQNSPSPVP 836
Query: 162 SQLPMGRDSREMLFLAEQP------PLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKS 215
S+ P + + + P P+P PP +PP + P + TPT
Sbjct: 837 SRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPT--------- 887
Query: 216 ASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQIL 275
+Q ++ + P Q P Q+ + P + A +L Q
Sbjct: 888 -PPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPT--APLLPPQ--------- 935
Query: 276 NQQQQQHHNYQAILPAPPKS--AGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNS 333
PA P S A G PP S ST +S + P + +
Sbjct: 936 --------------PATPLSQPAVSIEGQVSNPPSTS-STEVNSQAIAEKQPSQEVKMEA 980
Query: 334 TSLTGKPGALPANLDDMKVAELK-QELKLRSLPVSGTKTELIERLRAYQD-------QIS 385
+P PA+ ++E K ++ K+ S TEL ++ +D Q S
Sbjct: 981 KMEVDQPE--PADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSS 1038
Query: 386 PVPGAPK 392
P PG K
Sbjct: 1039 PAPGQSK 1045
Score = 33.5 bits (75), Expect = 0.95
Identities = 47/190 (24%), Positives = 72/190 (37%), Gaps = 18/190 (9%)
Query: 551 LKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHID 610
L L+ +KR QQP AP+G + +S Q S L +PS A +
Sbjct: 415 LPLKNAGDKRNQQPILTGAPVG--LGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALG 472
Query: 611 -PCAV--APGPPSVVVK-QEALQPEPEPV---PAPQLLLGPQGPSLIKGVAPPTLITDST 663
P V P P V K Q+ QP P P + P G + GV P+L++DS
Sbjct: 473 LPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSM 532
Query: 664 GTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPL---------QPLF 714
+ + +++ + S P ++QP + D+ L Q +F
Sbjct: 533 LHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIF 592
Query: 715 GTPTSLLKKE 724
TP K+
Sbjct: 593 PTPDPAALKD 602
Score = 33.1 bits (74), Expect = 1.2
Identities = 72/302 (23%), Positives = 108/302 (35%), Gaps = 53/302 (17%)
Query: 623 VKQEALQ---PEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSP 679
+KQ A + P+P+P + PQG G+ PPT+ G H + N N
Sbjct: 2085 IKQRAAKYANSNPQPIPGQPGM--PQGQP---GLQPPTM-PGQQGVHSNPAMQNMNPMQA 2138
Query: 680 GLS-SGSPQQPSSQPGSP---APAPSAQ-MDLEHPLQPLFGTPTSLLKKEP--------- 725
G+ +G PQQ Q P +P AQ M++ H P +L+++
Sbjct: 2139 GVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMP--SQFRDILRRQQMMQQQQQQG 2196
Query: 726 --PGYEEAMS-----QQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPS 778
PG M+ QQP+ QQ +Q G + + P +L + S
Sbjct: 2197 AGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGAS 2256
Query: 779 PKTV--------CGSPLAAQPSPSAELPQAAPPPPGSPSLPG-RLEDFLESSTGLPLLTS 829
+ GSP+ QP+P + P SP L G ++ + L + P
Sbjct: 2257 LQAYQQRLLQQQMGSPV--QPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP---- 2310
Query: 830 GHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPS--STMGLDLADGHLDS 887
P P HS S + + PSP S P P + + GH S
Sbjct: 2311 -QPVPSPRPQSQPPHS---SPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFAS 2366
Query: 888 MD 889
D
Sbjct: 2367 PD 2368
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 57.4 bits (137), Expect = 6e-08
Identities = 86/365 (23%), Positives = 132/365 (36%), Gaps = 74/365 (20%)
Query: 437 ASSGVVKFGSTGSTPPVSPTPSERSL---LSTGDENSTPGDTFGEMVTSPLTQLTLQASP 493
A SG S PP P P+ ++ L S P + S T+ L+A+
Sbjct: 424 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 483
Query: 494 LQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKL 553
L+ L L G A LE + + + +++Q E + R++++ ER K
Sbjct: 484 LKSLRSR---------LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR 534
Query: 554 QLEQEKRAQ----QPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHI 609
+ E+E++ + P+ PL V +N S + + PA P S+ APA
Sbjct: 535 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPA---- 590
Query: 610 DPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVL 669
P P P P P + P P PP + TG
Sbjct: 591 --------------------PAPTPTPTP---VQPTSP-------PPGPVAQPTGPQ--- 617
Query: 670 TVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM-DLEHPLQPLFGTPTSLLKKE---- 724
S G +SG QP+ P PAP P+ + P P T TSLL +
Sbjct: 618 ------PQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVP 671
Query: 725 PPGYEEAMSQ---------QPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKE 775
PPG + + P G+ M + D+ + + ++S E P LP
Sbjct: 672 PPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDP-LPPVF 730
Query: 776 KPSPK 780
+PK
Sbjct: 731 SGTPK 735
Score = 37.7 bits (86), Expect = 0.050
Identities = 60/256 (23%), Positives = 87/256 (33%), Gaps = 55/256 (21%)
Query: 597 FNPSLAAPATNHIDPCAVAPGP--PSVVVKQEALQPEPEPVPAPQ---LLLGPQGPSLIK 651
F PSL A+ P P P PS E+ P P P P P + L Q P +
Sbjct: 401 FQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVS 460
Query: 652 GVAPPT---LITDSTGTHL----VLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM 704
APP I+D+T L + ++ ++ D P +P+ P P A Q
Sbjct: 461 EPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE-----PRKPVTAQERQR 515
Query: 705 DLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENG---SSSQQMDDLFDILIQSGEI 761
+ E + ++E E Q+ +++E G S D L +++ +
Sbjct: 516 EREEKRRR---------RQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDR 566
Query: 762 S----------------------ADFKEPPSLPGKEKPSPKTVCGSPLAAQP----SPSA 795
S A P P + P P QP S S
Sbjct: 567 SLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSG 626
Query: 796 ELPQAAPPPPGSPSLP 811
+PQ A PPPG P
Sbjct: 627 PVPQPACPPPGPAPHP 642
Score = 32.0 bits (71), Expect = 2.8
Identities = 44/180 (24%), Positives = 69/180 (38%), Gaps = 18/180 (10%)
Query: 696 PAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDIL 755
P+ SA L HP + P PP ++ A ++ +E + + ++ D
Sbjct: 332 PSARISAAAALRHPFLAKYHDPDDEPDCAPP-FDFAFDREALTRERIKEAI-VAEIEDFH 389
Query: 756 IQSGEISADFKEPPSL-PGKEKPSPKTVCGSPLAAQPSPSAELPQAA--PPPPGSPSLPG 812
+ I + PSL P +P G P PSP A A PPP P PG
Sbjct: 390 ARREGIRQQIRFQPSLQPVASEP------GCPDVEMPSPWAPSGDCAMESPPPAPPPCPG 443
Query: 813 RLEDFLESSTGLPLLTSGHDGPEPLSLIDD-----LHSQMLSS--TAILDHPPSPMDTSE 865
D ++ + P S P+ I D L + +L S + + D P +P++ E
Sbjct: 444 PAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE 503
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 57.4 bits (137), Expect = 6e-08
Identities = 86/365 (23%), Positives = 132/365 (36%), Gaps = 74/365 (20%)
Query: 437 ASSGVVKFGSTGSTPPVSPTPSERSL---LSTGDENSTPGDTFGEMVTSPLTQLTLQASP 493
A SG S PP P P+ ++ L S P + S T+ L+A+
Sbjct: 424 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 483
Query: 494 LQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKL 553
L+ L L G A LE + + + +++Q E + R++++ ER K
Sbjct: 484 LKSLRSR---------LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR 534
Query: 554 QLEQEKRAQ----QPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHI 609
+ E+E++ + P+ PL V +N S + + PA P S+ APA
Sbjct: 535 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPA---- 590
Query: 610 DPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVL 669
P P P P P + P P PP + TG
Sbjct: 591 --------------------PAPTPTPTP---VQPTSP-------PPGPVAQPTGPQ--- 617
Query: 670 TVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM-DLEHPLQPLFGTPTSLLKKE---- 724
S G +SG QP+ P PAP P+ + P P T TSLL +
Sbjct: 618 ------PQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVP 671
Query: 725 PPGYEEAMSQ---------QPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKE 775
PPG + + P G+ M + D+ + + ++S E P LP
Sbjct: 672 PPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDP-LPPVF 730
Query: 776 KPSPK 780
+PK
Sbjct: 731 SGTPK 735
Score = 37.7 bits (86), Expect = 0.050
Identities = 60/256 (23%), Positives = 87/256 (33%), Gaps = 55/256 (21%)
Query: 597 FNPSLAAPATNHIDPCAVAPGP--PSVVVKQEALQPEPEPVPAPQ---LLLGPQGPSLIK 651
F PSL A+ P P P PS E+ P P P P P + L Q P +
Sbjct: 401 FQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVS 460
Query: 652 GVAPPT---LITDSTGTHL----VLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM 704
APP I+D+T L + ++ ++ D P +P+ P P A Q
Sbjct: 461 EPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE-----PRKPVTAQERQR 515
Query: 705 DLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENG---SSSQQMDDLFDILIQSGEI 761
+ E + ++E E Q+ +++E G S D L +++ +
Sbjct: 516 EREEKRRR---------RQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDR 566
Query: 762 S----------------------ADFKEPPSLPGKEKPSPKTVCGSPLAAQP----SPSA 795
S A P P + P P QP S S
Sbjct: 567 SLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSG 626
Query: 796 ELPQAAPPPPGSPSLP 811
+PQ A PPPG P
Sbjct: 627 PVPQPACPPPGPAPHP 642
Score = 32.0 bits (71), Expect = 2.8
Identities = 44/180 (24%), Positives = 69/180 (38%), Gaps = 18/180 (10%)
Query: 696 PAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDIL 755
P+ SA L HP + P PP ++ A ++ +E + + ++ D
Sbjct: 332 PSARISAAAALRHPFLAKYHDPDDEPDCAPP-FDFAFDREALTRERIKEAI-VAEIEDFH 389
Query: 756 IQSGEISADFKEPPSL-PGKEKPSPKTVCGSPLAAQPSPSAELPQAA--PPPPGSPSLPG 812
+ I + PSL P +P G P PSP A A PPP P PG
Sbjct: 390 ARREGIRQQIRFQPSLQPVASEP------GCPDVEMPSPWAPSGDCAMESPPPAPPPCPG 443
Query: 813 RLEDFLESSTGLPLLTSGHDGPEPLSLIDD-----LHSQMLSS--TAILDHPPSPMDTSE 865
D ++ + P S P+ I D L + +L S + + D P +P++ E
Sbjct: 444 PAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE 503
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 57.4 bits (137), Expect = 6e-08
Identities = 86/365 (23%), Positives = 132/365 (36%), Gaps = 74/365 (20%)
Query: 437 ASSGVVKFGSTGSTPPVSPTPSERSL---LSTGDENSTPGDTFGEMVTSPLTQLTLQASP 493
A SG S PP P P+ ++ L S P + S T+ L+A+
Sbjct: 424 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 483
Query: 494 LQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKL 553
L+ L L G A LE + + + +++Q E + R++++ ER K
Sbjct: 484 LKSLRSR---------LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR 534
Query: 554 QLEQEKRAQ----QPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHI 609
+ E+E++ + P+ PL V +N S + + PA P S+ APA
Sbjct: 535 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPA---- 590
Query: 610 DPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVL 669
P P P P P + P P PP + TG
Sbjct: 591 --------------------PAPTPTPTP---VQPTSP-------PPGPVAQPTGPQ--- 617
Query: 670 TVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM-DLEHPLQPLFGTPTSLLKKE---- 724
S G +SG QP+ P PAP P+ + P P T TSLL +
Sbjct: 618 ------PQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVP 671
Query: 725 PPGYEEAMSQ---------QPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKE 775
PPG + + P G+ M + D+ + + ++S E P LP
Sbjct: 672 PPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDP-LPPVF 730
Query: 776 KPSPK 780
+PK
Sbjct: 731 SGTPK 735
Score = 37.7 bits (86), Expect = 0.050
Identities = 60/256 (23%), Positives = 87/256 (33%), Gaps = 55/256 (21%)
Query: 597 FNPSLAAPATNHIDPCAVAPGP--PSVVVKQEALQPEPEPVPAPQ---LLLGPQGPSLIK 651
F PSL A+ P P P PS E+ P P P P P + L Q P +
Sbjct: 401 FQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVS 460
Query: 652 GVAPPT---LITDSTGTHL----VLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM 704
APP I+D+T L + ++ ++ D P +P+ P P A Q
Sbjct: 461 EPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE-----PRKPVTAQERQR 515
Query: 705 DLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENG---SSSQQMDDLFDILIQSGEI 761
+ E + ++E E Q+ +++E G S D L +++ +
Sbjct: 516 EREEKRRR---------RQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDR 566
Query: 762 S----------------------ADFKEPPSLPGKEKPSPKTVCGSPLAAQP----SPSA 795
S A P P + P P QP S S
Sbjct: 567 SLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSG 626
Query: 796 ELPQAAPPPPGSPSLP 811
+PQ A PPPG P
Sbjct: 627 PVPQPACPPPGPAPHP 642
Score = 32.0 bits (71), Expect = 2.8
Identities = 44/180 (24%), Positives = 69/180 (38%), Gaps = 18/180 (10%)
Query: 696 PAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDIL 755
P+ SA L HP + P PP ++ A ++ +E + + ++ D
Sbjct: 332 PSARISAAAALRHPFLAKYHDPDDEPDCAPP-FDFAFDREALTRERIKEAI-VAEIEDFH 389
Query: 756 IQSGEISADFKEPPSL-PGKEKPSPKTVCGSPLAAQPSPSAELPQAA--PPPPGSPSLPG 812
+ I + PSL P +P G P PSP A A PPP P PG
Sbjct: 390 ARREGIRQQIRFQPSLQPVASEP------GCPDVEMPSPWAPSGDCAMESPPPAPPPCPG 443
Query: 813 RLEDFLESSTGLPLLTSGHDGPEPLSLIDD-----LHSQMLSS--TAILDHPPSPMDTSE 865
D ++ + P S P+ I D L + +L S + + D P +P++ E
Sbjct: 444 PAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE 503
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 57.4 bits (137), Expect = 6e-08
Identities = 86/365 (23%), Positives = 132/365 (36%), Gaps = 74/365 (20%)
Query: 437 ASSGVVKFGSTGSTPPVSPTPSERSL---LSTGDENSTPGDTFGEMVTSPLTQLTLQASP 493
A SG S PP P P+ ++ L S P + S T+ L+A+
Sbjct: 285 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 344
Query: 494 LQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKL 553
L+ L L G A LE + + + +++Q E + R++++ ER K
Sbjct: 345 LKSLRSR---------LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR 395
Query: 554 QLEQEKRAQ----QPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHI 609
+ E+E++ + P+ PL V +N S + + PA P S+ APA
Sbjct: 396 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPA---- 451
Query: 610 DPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVL 669
P P P P P + P P PP + TG
Sbjct: 452 --------------------PAPTPTPTP---VQPTSP-------PPGPVAQPTGPQ--- 478
Query: 670 TVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM-DLEHPLQPLFGTPTSLLKKE---- 724
S G +SG QP+ P PAP P+ + P P T TSLL +
Sbjct: 479 ------PQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVP 532
Query: 725 PPGYEEAMSQ---------QPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKE 775
PPG + + P G+ M + D+ + + ++S E P LP
Sbjct: 533 PPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDP-LPPVF 591
Query: 776 KPSPK 780
+PK
Sbjct: 592 SGTPK 596
Score = 37.7 bits (86), Expect = 0.050
Identities = 60/256 (23%), Positives = 87/256 (33%), Gaps = 55/256 (21%)
Query: 597 FNPSLAAPATNHIDPCAVAPGP--PSVVVKQEALQPEPEPVPAPQ---LLLGPQGPSLIK 651
F PSL A+ P P P PS E+ P P P P P + L Q P +
Sbjct: 262 FQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVS 321
Query: 652 GVAPPT---LITDSTGTHL----VLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQM 704
APP I+D+T L + ++ ++ D P +P+ P P A Q
Sbjct: 322 EPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE-----PRKPVTAQERQR 376
Query: 705 DLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENG---SSSQQMDDLFDILIQSGEI 761
+ E + ++E E Q+ +++E G S D L +++ +
Sbjct: 377 EREEKRRR---------RQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDR 427
Query: 762 S----------------------ADFKEPPSLPGKEKPSPKTVCGSPLAAQP----SPSA 795
S A P P + P P QP S S
Sbjct: 428 SLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSG 487
Query: 796 ELPQAAPPPPGSPSLP 811
+PQ A PPPG P
Sbjct: 488 PVPQPACPPPGPAPHP 503
Score = 32.0 bits (71), Expect = 2.8
Identities = 44/180 (24%), Positives = 69/180 (38%), Gaps = 18/180 (10%)
Query: 696 PAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDIL 755
P+ SA L HP + P PP ++ A ++ +E + + ++ D
Sbjct: 193 PSARISAAAALRHPFLAKYHDPDDEPDCAPP-FDFAFDREALTRERIKEAI-VAEIEDFH 250
Query: 756 IQSGEISADFKEPPSL-PGKEKPSPKTVCGSPLAAQPSPSAELPQAA--PPPPGSPSLPG 812
+ I + PSL P +P G P PSP A A PPP P PG
Sbjct: 251 ARREGIRQQIRFQPSLQPVASEP------GCPDVEMPSPWAPSGDCAMESPPPAPPPCPG 304
Query: 813 RLEDFLESSTGLPLLTSGHDGPEPLSLIDD-----LHSQMLSS--TAILDHPPSPMDTSE 865
D ++ + P S P+ I D L + +L S + + D P +P++ E
Sbjct: 305 PAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPE 364
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 56.6 bits (135), Expect = 1e-07
Identities = 123/561 (21%), Positives = 192/561 (34%), Gaps = 123/561 (21%)
Query: 416 STGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDT 475
++ PAL G P+ + + + S P +P + S G+
Sbjct: 597 ASDPALQPPGGVPSSLAESHLCLPSAFALSIPRSGPGSDFSPGDSYASDAASGLSDVGEG 656
Query: 476 FGEMVTSPLTQLTLQA-SPLQIL-VKEEGPRAGSCCLSPGG------RAELEGRDKDQML 527
G+M P L + S L++ V ++ R C L R +L+G +++
Sbjct: 657 MGQMRRPPGRNLRRRPRSRLRVTSVSDQNDRVVECQLQTHNSKMVTFRFDLDGDSPEEIA 716
Query: 528 -----------QEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRA----QQPAPAPA--- 569
E+D + + ++++ + L++R +E + ++PAP PA
Sbjct: 717 AAMVYNEFILPSERDGFLRRIREIIQRVETLLKRDTGPMEAAEDTLSPQEEPAPLPALPV 776
Query: 570 PLGTPVKQE------------NSFSSCQLSQ-QPLGPAHPFNPSLAA------PATNHID 610
PL P +E +FS+ S PL P +PF+P P T+
Sbjct: 777 PLPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTPISPGPIFPITS--P 834
Query: 611 PCAVAPGPPSVVVKQEALQPEPEPVPAP-------------------------------- 638
PC +P P S + Q + P P P +P
Sbjct: 835 PCHPSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSP 894
Query: 639 ---QLLLG-------PQGPSLIKGVAPPTLITDSTGTHLVLTVTNK-NADSPGLSSGSPQ 687
Q+ L P S A P L S + V+TV + SPGL S SP
Sbjct: 895 TCSQVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPP 954
Query: 688 QPSSQ-PGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKE--PPGYEEAMSQQPKQQENGSS 744
P S P P P P A E P T+ ++ E PP + +
Sbjct: 955 APPSPLPSLPLPPPVAPGGQESP-----SPHTAEVESEASPPPARPLPGEARLAPISEEG 1009
Query: 745 SQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPP 804
Q+ G + P+ P +P+ T+ GSP + P ++E
Sbjct: 1010 KPQL---------VGRFQVTSSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTEDSA 1060
Query: 805 PGSPSLPGRLEDFLESSTGL--PLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPM- 861
G P L + ++ GL + G DG EP Q+ S L H PSP+
Sbjct: 1061 GGGPETREALAESDRAAEGLGAGVEEEGDDGKEP---------QVGGSPQPLSH-PSPVW 1110
Query: 862 ---DTSELHFVPEPSSTMGLD 879
S L E S + G D
Sbjct: 1111 MNYSYSSLCLSSEESESSGED 1131
>gi|32698970 MEF2 activating motif and SAP domain containing
transcriptional regulator isoform 2 [Homo sapiens]
Length = 312
Score = 56.6 bits (135), Expect = 1e-07
Identities = 77/303 (25%), Positives = 116/303 (38%), Gaps = 32/303 (10%)
Query: 642 LGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPS 701
LGP GPSL +G TDS H + + PG+ S SP + +
Sbjct: 20 LGPPGPSLWEG-------TDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEEL 72
Query: 702 AQMDLEHPLQ----PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQ 757
+L L+ P+ GT + LL++ G +P+++++ + + L +
Sbjct: 73 TVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAP-WPRLKPKALA 131
Query: 758 SGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAP---PPPGSPSLPGRL 814
+ K PS P P+ A P+P+ P AAP P G S L
Sbjct: 132 AARRQGSVK--PSAASHRPPLPRAADTPGTAPAPTPTPA-PAAAPALTPSSGPGSAALTL 188
Query: 815 EDFLESSTGLPLLTSGH-------DGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELH 867
E+ L+ + L D EP + + S +L P S +
Sbjct: 189 EEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVF 248
Query: 868 F--VPEPSSTMGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDFLDGHDLQL 925
+P P+++ D DS+DWLE SGGP L P PS+FS D D +L
Sbjct: 249 SSSLPSPTNSSSPSPRDP-TDSLDWLEALSGGPPLGSGP---PPPSIFSADLSDSSSSRL 304
Query: 926 HWD 928
WD
Sbjct: 305 -WD 306
Score = 52.0 bits (123), Expect = 3e-06
Identities = 49/163 (30%), Positives = 71/163 (43%), Gaps = 35/163 (21%)
Query: 291 APPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPA----- 345
A P++ G ALG PP SL + S P P R + LT P +P+
Sbjct: 11 ADPQAEGSALG----PPGPSLW---EGTDSQQPHP----RMKPSPLTPCPPGVPSPSPPP 59
Query: 346 --------NLDDMKVAELKQELKLRSLPVSGTKTELIERLRA-----------YQDQISP 386
L+++ V+EL+Q+L+LR LPVSGTK+ L+ER+R +D +
Sbjct: 60 HKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAG 119
Query: 387 VPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPA 429
P P A + + G V + + R A G APA
Sbjct: 120 APWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA 162
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 56.6 bits (135), Expect = 1e-07
Identities = 90/378 (23%), Positives = 129/378 (34%), Gaps = 76/378 (20%)
Query: 464 STGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGP------------RAGSCCLS 511
S E TP + E P T+ A + GP R G C
Sbjct: 380 SPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKP 439
Query: 512 PGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPL 571
P D+D+ +++ KQ + + VER + + E+E+R Q A
Sbjct: 440 PAPE------DEDEAWRQRRKQSSSEISLA------VERARRRREEEERRMQEERRAACA 487
Query: 572 GTPVKQENSFSSC--QLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQ 629
+ + F + +L +P P AAP+T P PP V K+
Sbjct: 488 EKLKRLDEKFGAPDKRLKAEPAAPP-------AAPST---------PAPPPAVPKELPAP 531
Query: 630 PEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQP 689
P P P AP P+ P+ APP T + G T+ + + SSGS +
Sbjct: 532 PAPPPASAPTPETEPEEPA----QAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEAS 587
Query: 690 SSQPGSPA-PAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENG------ 742
+P P+ P ++ P P + K EP G ++QP Q G
Sbjct: 588 PVEPQLPSKEGPEPPEEVPPPTTP------PVPKVEPKGDGIGPTRQPPSQGLGYPKYQK 641
Query: 743 -----SSSQQMDDLFDILIQ-SGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAE 796
QQ + L Q + PP+ P P T L A P+P
Sbjct: 642 SLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVT-----LGAVPAPQ-- 694
Query: 797 LPQAAPPPPGSPSLPGRL 814
APPPP PG L
Sbjct: 695 ----APPPPPKALYPGAL 708
Score = 44.7 bits (104), Expect = 4e-04
Identities = 78/331 (23%), Positives = 108/331 (32%), Gaps = 60/331 (18%)
Query: 558 EKRAQQPAPAPAPLGTP----------VKQENSFSSCQLSQQPLGPAHPFNPSLAAPATN 607
E ++PA AP TP V S SS P P PS P
Sbjct: 543 ETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPP 602
Query: 608 HIDPCAVAPGPPSVVVKQEALQPEPEP------VPAPQLLLGP-----QGPSLIK----- 651
P P P V K + + P +P P Q L P Q L+K
Sbjct: 603 EEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQH 662
Query: 652 -------GVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGS---PAPAPS 701
G APPT + S + L P + P + PG+ P P P
Sbjct: 663 QWQQHQQGSAPPTPVPPSPPQPVTLGAV------PAPQAPPPPPKALYPGALGRPPPMPP 716
Query: 702 AQMDLEHPLQPLFGTPTSL-----LKKEPPG-YEEAMSQQPKQQENGSSSQQMDDLFDIL 755
D + P + P L L PPG + + + + GSSS+ D +
Sbjct: 717 MNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAM 776
Query: 756 IQS-GEISADFKEP------PSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSP 808
++ G D K + P + +P + + +E P PPPP
Sbjct: 777 LRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLA 836
Query: 809 SLPGRLEDFLESSTGLPL--LTSGHDGPEPL 837
S PG E+ + G P+ GP PL
Sbjct: 837 SYPGFPEN---GAPGPPISRFPLEEPGPRPL 864
Score = 38.9 bits (89), Expect = 0.023
Identities = 81/358 (22%), Positives = 115/358 (32%), Gaps = 81/358 (22%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPS- 620
Q P+P P P + + SS ++P P + D V+P PP
Sbjct: 1508 QGPSPRPPTRYEPQRVNSGLSSDPHFEEP-------GPMVRGVGGTPRDSAGVSPFPPKR 1560
Query: 621 ---VVVKQEALQPEPEPVPAPQLLLG--PQGPSLIKGVAPPTLITDSTGTHLVLTVTNKN 675
K E LQ E P P LG P+GP P + TGT LT N
Sbjct: 1561 RERPPRKPELLQEESLPPPHSSGFLGSKPEGPG-------PQAESRDTGTE-ALTPHIWN 1612
Query: 676 ADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQ 735
S S + S +P PL P + + + G + + Q
Sbjct: 1613 RLHTATSRKSYRPSSMEPWM------------EPLSPFEDVAGTEMSQSDSGVDLSGDSQ 1660
Query: 736 PKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQP---S 792
+G SQ+ G + + PP PG P C P ++P
Sbjct: 1661 VS---SGPCSQRSSP-------DGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRP 1710
Query: 793 PSA-------ELPQAAPPPPG-----------SPSLPGRLEDFLESSTGLPLLTSGHDGP 834
P A ELP+ P PPG + PG + + TS D
Sbjct: 1711 PPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSD 1770
Query: 835 EPLSLIDDLHSQMLSSTAILDHPPSPMDTSEL-----------------HFVPEPSST 875
L + D L ++ + ++ + P D L H VPEPSS+
Sbjct: 1771 LRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSS 1828
Score = 38.5 bits (88), Expect = 0.029
Identities = 95/423 (22%), Positives = 144/423 (34%), Gaps = 70/423 (16%)
Query: 92 ESSLKEAIIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEAR-VSEPLL 150
+SS + ++ V + + + E+ A + + E G+ L+A + P
Sbjct: 455 QSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAA 514
Query: 151 SATSASPTQVVSQLPMGRDSREMLFLAEQPPLPPPPLLPPSLTNG---TTIPTAKSTPTL 207
+T A P V +LP PP PPP P T P A+STPT
Sbjct: 515 PSTPAPPPAVPKELPA-------------PPAPPPASAPTPETEPEEPAQAPPAQSTPTP 561
Query: 208 IKQSQPK------SASEKSQRSKKAKELKPKVKKLKYHQYIPPDQ--------------- 246
+ P S S S S +A ++P++ + + PP++
Sbjct: 562 GVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE--PPEEVPPPTTPPVPKVEPK 619
Query: 247 -----------KQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQ---QHHNYQAILPAP 292
Q G P S Q+QQ Q Q+L QQQQ Q H + P P
Sbjct: 620 GDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQ---QEQLLKQQQQHQWQQHQQGSAPPTP 676
Query: 293 -PKSAGEALGSSGTPPVRSLSTTNSSSSSGAPG-PCGLARQNSTSLTGKPGALPANLDDM 350
P S + + P ++ + GA G P + N + +P +D
Sbjct: 677 VPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMN---FDPRWMMIPPYVDPR 733
Query: 351 KVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAF 410
L+ L P + L+ R R+ S P APA +L + G V
Sbjct: 734 L---LQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPA---MLRERGTPPVDP 787
Query: 411 PAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENS 470
A + G A P + ++ G TPPV P P + EN
Sbjct: 788 KLAWV--GDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENG 845
Query: 471 TPG 473
PG
Sbjct: 846 APG 848
Score = 35.0 bits (79), Expect = 0.32
Identities = 50/223 (22%), Positives = 78/223 (34%), Gaps = 27/223 (12%)
Query: 568 PAPLGTPVKQ--ENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQ 625
P PL +P++Q + + P+ P P+ S N APGPP + +
Sbjct: 803 PRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENG------APGPP--ISRF 854
Query: 626 EALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTN------KNADSP 679
+P P P+P P P + K PP LT + S
Sbjct: 855 PLEEPGPRPLPWP-----PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSG 909
Query: 680 GLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLK--KEPPGYEEAMSQQPK 737
G P++ S P P + P +P G P K+PP + PK
Sbjct: 910 GQGPPPPRRESRTETRWGPRPGSSRRGIPPEEP--GAPPRRAGPIKKPPPPTKVEELPPK 967
Query: 738 QQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPK 780
E G + + + I G++ + PP+ G P+P+
Sbjct: 968 PLEQGDETPKPPKPDPLKITKGKLGGPKETPPN--GNLSPAPR 1008
Score = 33.9 bits (76), Expect = 0.72
Identities = 56/248 (22%), Positives = 76/248 (30%), Gaps = 34/248 (13%)
Query: 594 AHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGV 653
+ P P A T+ P PGPP+ P P P P GP G +G
Sbjct: 383 SEPPTPKTAWAETSR--PPETEPGPPA------PKPPLPPPHRGPAGNWGPPGDYPDRGG 434
Query: 654 AP--PTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQ 711
P P D + + S + ++ + +A + L
Sbjct: 435 PPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLD 494
Query: 712 PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSL 771
FG P LK EP A S + + PP+
Sbjct: 495 EKFGAPDKRLKAEPAAPPAAPSTPAPPPA--------------------VPKELPAPPAP 534
Query: 772 PGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPP---PGSPSLPGRLEDFLESSTGLPLLT 828
P P+P+T P A P+ S P A P G S E+S P L
Sbjct: 535 PPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLP 594
Query: 829 SGHDGPEP 836
S +GPEP
Sbjct: 595 S-KEGPEP 601
Score = 30.4 bits (67), Expect = 8.0
Identities = 34/97 (35%), Positives = 42/97 (43%), Gaps = 12/97 (12%)
Query: 564 PAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHP--FNPSLAAPATNHIDPCAVAPGPPSV 621
P+P P V+Q+ S PL P F PS APA + P + P
Sbjct: 1935 PSPLPDTSLLQVRQDLP-SPSDFYSTPLQPGGQSGFLPS-GAPAQQMLLPMVDSQLP--- 1989
Query: 622 VVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTL 658
VV +L P P P P P LL P GP+L PP+L
Sbjct: 1990 VVNFGSLPPAPPPAPPPLSLL-PVGPAL----QPPSL 2021
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 55.8 bits (133), Expect = 2e-07
Identities = 88/347 (25%), Positives = 121/347 (34%), Gaps = 81/347 (23%)
Query: 564 PAPAPAPLGTPVK---------QENSFSSCQLSQQPLGPAHPFNPSLAAPA--TNHIDPC 612
P PAP P P K + + P P P P+ PA ++I P
Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Query: 613 AVAPG---PPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVA----PPTLITDSTGT 665
P PP + KQ++ +P P P + PS++K +A PP
Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV------PSVVKQIASQFPPPPTPPAMESQ 881
Query: 666 HLVLTVTNKNADSPGLSSGSPQ-QPSS----QPGSPAPAPSAQMDLEHPLQPLFGTPTSL 720
L N SP P+ QPSS P P P P + + P P S
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP-------PPSP 934
Query: 721 LKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLP-------- 772
+ PP S P ++GS ++ S S K+PP P
Sbjct: 935 VPAPPPPPPPTASPTP--DKSGSPGKKT---------SKTSSPGGKKPPPTPQRNSSIKS 983
Query: 773 --GKEKPSPKTVCGSPLAAQPSPSAEL---------PQAAPPPPG-----SPSLPGRLED 816
G E P PK L ++ +P AE P AAPP PG +LPG L+
Sbjct: 984 SSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQ 1043
Query: 817 FLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDT 863
S+ L G D S++ + S + D PP P +T
Sbjct: 1044 GCVSAKAPVLSGRGKD-----SVV-----EFPSPPSDSDFPPPPPET 1080
Score = 52.8 bits (125), Expect = 2e-06
Identities = 70/271 (25%), Positives = 105/271 (38%), Gaps = 44/271 (16%)
Query: 556 EQEKRAQQPAPAP-APLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAV 614
+Q+ +P P+P +P+ + VKQ S Q P PA P PA V
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIAS----QFPPPPTPPAMESQPLKPVPAN-------V 890
Query: 615 APGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLI-TDSTGTHLVLTVTN 673
AP P V + QP PVP+P P SL+ PP+ + + T
Sbjct: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP 950
Query: 674 KNADSPGLSSGSPQQPSSQPGSPAPAPSAQM----DLEHPLQPLFGTPTSLLKK-EPPGY 728
+ SPG + P + P P ++ + EHP +P + SL+ K PP
Sbjct: 951 DKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP-EPKRPSVDSLVSKFTPPAE 1009
Query: 729 EEAMSQQ--------PKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPK 780
+ S++ PK + S + ++Q G +SA + P L G+ K S
Sbjct: 1010 SGSPSKETLPPPAAPPKPGKLNLSGVNLPG----VLQQGCVSA---KAPVLSGRGKDS-- 1060
Query: 781 TVCGSPLAAQPSPSAELPQAAPPPPGSPSLP 811
+ PSP ++ PPPP LP
Sbjct: 1061 ------VVEFPSPPSD--SDFPPPPPETELP 1083
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/228 (24%), Positives = 79/228 (34%), Gaps = 42/228 (18%)
Query: 619 PSVVVKQEALQPEPEPVPAP--------QLLLGPQGPSLIKGVAPPTLITDSTGTHLVLT 670
P ++V + P P P P P QL P PSL + APP + H+
Sbjct: 699 PQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758
Query: 671 VTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPL-----------------QPL 713
P + + P Q +P PAP++ + + QP
Sbjct: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA 818
Query: 714 FGTPTSLLKKEPPGYEEAMSQQ--PKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSL 771
F P S + PP + PKQQ + + L + +I++ F PP+
Sbjct: 819 F--PASYIPPSPPTPPVPVPPPTLPKQQ-SFCAKPPPSPLSPVPSVVKQIASQFPPPPTP 875
Query: 772 PGKE----KPSPKTVC-GSPLAAQPSPS-------AELPQAAPPPPGS 807
P E KP P V SP A + P P PPPP S
Sbjct: 876 PAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923
Score = 37.7 bits (86), Expect = 0.050
Identities = 77/348 (22%), Positives = 121/348 (34%), Gaps = 70/348 (20%)
Query: 136 SVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREM--LFLAEQPPLPPPPLLPPSLT 193
++P+P + P++ T A+P +P + ++ PP PP P+ PP+L
Sbjct: 784 TIPAPTSTKTVAPVV--TQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLP 841
Query: 194 NGTTI-----PTAKS-TPTLIKQ------SQPKSASEKSQRSKK-----AKELKPKVK-K 235
+ P+ S P+++KQ P + +SQ K A + P VK K
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Query: 236 LKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKS 295
K+ P D PP +SS L A P PP +
Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESS----------------LVFPPPPPSPVPAPPPPPPPT 945
Query: 296 AGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAEL 355
A SG+P ++ T++ P P Q ++S+ GA V L
Sbjct: 946 ASPTPDKSGSPGKKTSKTSSPGGKKPPPTP-----QRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 356 KQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARL 415
+ + S +K L P P AP P L+ +G +
Sbjct: 1001 VSKFTPPAESGSPSKETL------------PPPAAPPKPGK---LNLSGVNL-------- 1037
Query: 416 STGPALVAAGLAPAEV-VVATVASSGVVKFGSTGSTPPVSPTPSERSL 462
P ++ G A+ V++ VV+F S S P P E L
Sbjct: 1038 ---PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL 1082
Score = 33.9 bits (76), Expect = 0.72
Identities = 51/211 (24%), Positives = 67/211 (31%), Gaps = 41/211 (19%)
Query: 671 VTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEE 730
VT A P S P P P P P P L P G+ + K Y
Sbjct: 616 VTPYTASQP--SPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK----YST 669
Query: 731 AMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQ 790
Q Q +G+ LF +PP+ P + S K P
Sbjct: 670 ITRLQNASQHSGA-------LF--------------KPPTPPVMQSQSVKPQILVP---- 704
Query: 791 PSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSS 850
P+ +P PPPP P PG L+ + P L P PL + H ++
Sbjct: 705 --PNGVVPPPPPPPP--PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760
Query: 851 TAILDHPPSP------MDTSELHFVPEPSST 875
PP P L +P P+ST
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVTIPAPTST 791
Score = 33.1 bits (74), Expect = 1.2
Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 16/137 (11%)
Query: 93 SSLKEAIIVGQVNYPKVADSSSFDEDSSDA-LSPEQPASHESQGSVPSPLEARV------ 145
+SL + I + + +S S + SD+ +S QPA H S+ S + +
Sbjct: 527 TSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQ 586
Query: 146 ----SEPLLSATSASPTQVVSQL-PMGRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPT 200
S+ + + + T +V L P + PPLPPPP PP P
Sbjct: 587 LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP----PPPPP 642
Query: 201 AKSTPTLIKQSQPKSAS 217
P L QS P + S
Sbjct: 643 PPPPPPLPSQSAPSAGS 659
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 55.5 bits (132), Expect = 2e-07
Identities = 83/315 (26%), Positives = 109/315 (34%), Gaps = 46/315 (14%)
Query: 562 QQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPS--LAAPATNHIDPCAVAPGPP 619
Q P P P P T V + S ++ Q QP P P + APA + P +P PP
Sbjct: 206 QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP--PSPHPP 263
Query: 620 SVVVKQEALQPEPEPVPAPQLLLGPQG-PSLIKGVAPPTLITDSTGTHLVLTVTNKNADS 678
P P P P Q L G G PS PP G H +
Sbjct: 264 ----------PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA-------G 306
Query: 679 PGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQ 738
P L P QP G P A Q L P P + L+ P SQQP +
Sbjct: 307 PLLQHPGPPQPF---GLPPQASQGQAPL--GTSPAAAYPHTSLQL-PASQSALQSQQPPR 360
Query: 739 QENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELP 798
++ L + K PP+ P + P+P+ P + PSP + +
Sbjct: 361 EQP-------------LPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS-MN 406
Query: 799 QAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPP 858
PPPP L S+ PL P P S L+ + L PP
Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS---PAQPPGLTQSQNLPPPP 463
Query: 859 SPMDTSELHFV-PEP 872
+ + LH V P+P
Sbjct: 464 ASHPPTGLHQVAPQP 478
Score = 46.6 bits (109), Expect = 1e-04
Identities = 140/629 (22%), Positives = 219/629 (34%), Gaps = 114/629 (18%)
Query: 190 PSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQD 249
P+ +G T P + + + S SA+ S KA+ +K KK+K +
Sbjct: 38 PASPDGRTSPINEDIRSSGRNSP--SAASTSSNDSKAETVKKSAKKVK-----------E 84
Query: 250 RGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEALGSSGTPPVR 309
+ P+ S+ Q++++ + ++ + Q I + P S E G S
Sbjct: 85 EASSPLKSNKR---QREKVASDTEEADRTSSKKTKTQEI--SRPNSPSEGEGES------ 133
Query: 310 SLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELKLRSLPVSGT 369
S + S + G+ P + + N ++ P P + + + +Q++ P
Sbjct: 134 --SDSRSVNDEGSSDPKDIDQDNRSTSPSIPS--PQDNESDSDSSAQQQMLQAQPPALQA 189
Query: 370 KTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPA 429
T + + +P P+AT++ + P A S P A AP
Sbjct: 190 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS------PTA--SQAPNQPQAPTAPV 241
Query: 430 EVVVATVASSGVVKFGSTGSTPP-VSPTPSERSLLSTGDENSTPGDTFGEMV-TSPLTQL 487
A + + + PP SP P + L + + S P + P
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH 301
Query: 488 TLQASPLQILVKEEGPRA--GSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQ 545
+LQA PL ++ GP G + G+A L G Q+ A
Sbjct: 302 SLQAGPL---LQHPGPPQPFGLPPQASQGQAPL-GTSPAAAYPHTSLQLPA--------- 348
Query: 546 QLVERLKLQLEQEKRAQQPAPAPAPLGTP-VKQENSFSSCQLSQQPLGPAHPFNPSLAAP 604
+ LQ +Q R +QP P PAPL P +K + + Q P AH P L+ P
Sbjct: 349 ---SQSALQSQQPPR-EQPLP-PAPLAMPHIKPP---PTTPIPQLPAPQAHKHPPHLSGP 400
Query: 605 ATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTG 664
+ ++ A P PP++ P P L L PQ L A P +T S
Sbjct: 401 SPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 458
Query: 665 THLVLTVTNKNADSPGLSSGSPQQPSSQ----PGSPAPAPSAQMDLEHPLQPLFGTPTSL 720
L + GL +PQ P +Q PG P P + P P TP +
Sbjct: 459 ----LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP-------ITPPTCPSTSTPPA- 506
Query: 721 LKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPK 780
PG S QP +S G I+ G P P
Sbjct: 507 ----GPG----TSAQPPCSGAAASG-------------GSIAG---------GSSCPLPT 536
Query: 781 TVCGSPLAAQPSPSAELPQAAPPPPGSPS 809
+ + AE P++ PPPP SPS
Sbjct: 537 V----QIKEEALDDAEEPESPPPPPRSPS 561
Score = 44.3 bits (103), Expect = 5e-04
Identities = 123/525 (23%), Positives = 180/525 (34%), Gaps = 83/525 (15%)
Query: 122 ALSPEQPAS-----HESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFL 176
AL P++P S H S PL +P SA S + + Q P G S + L
Sbjct: 251 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP--SAPSHAQPPLHGQGPPGPHSLQAGPL 308
Query: 177 AEQPPLPPPPLLPPSLTNGT----TIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPK 232
+ P P P LPP + G T P A T ++ +SA + SQ+ + + L P
Sbjct: 309 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ-SQQPPREQPLPPA 367
Query: 233 VKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAP 292
+ H PP + P + L F + A LP P
Sbjct: 368 PLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPF--------------SMNANLPPP 412
Query: 293 PKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKV 352
P P+ SLST + S+ P P L Q S L P P
Sbjct: 413 P----------ALKPLSSLSTHHPPSAH--PPPLQLMPQ-SQPLPSSPAQPPG------- 452
Query: 353 AELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPA 412
L Q L P S T L Q++P P P A G + P
Sbjct: 453 --LTQSQNLPPPPASHPPTGL--------HQVAPQP-----PFAQHPFVPGGPPPITPPT 497
Query: 413 A-RLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENST 471
ST PA G + AS G + GS+ P V E +L + S
Sbjct: 498 CPSTSTPPA--GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ--IKEEALDDAEEPESP 553
Query: 472 PGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEG----RDKDQML 527
P + AS K SC + L G + +++ +
Sbjct: 554 PPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAI 613
Query: 528 QEKDKQIEALTRMLRQKQQLVER-LKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQL 586
++ ++ E R R++++ E+ + + E+E+ A++ A A + E S QL
Sbjct: 614 EKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSS-----AHEGRLSDPQL 668
Query: 587 SQQPLGPAHPFNPSLAAPATN-HIDPCAVAPGPPSVVVKQEALQP 630
S GP H PS P T P + P P++ E +P
Sbjct: 669 S----GPGH-MRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARP 708
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,576,779
Number of Sequences: 37866
Number of extensions: 2964643
Number of successful extensions: 30768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 1376
Number of HSP's that attempted gapping in prelim test: 19395
Number of HSP's gapped (non-prelim): 10034
length of query: 931
length of database: 18,247,518
effective HSP length: 112
effective length of query: 819
effective length of database: 14,006,526
effective search space: 11471344794
effective search space used: 11471344794
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.