Search of human proteins with 9845509

Search of human proteins with 9845509

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform
Rac1b [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   434   e-122
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   384   e-107
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   363   e-101
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   357   4e-99
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           274   5e-74
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            274   5e-74
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           272   1e-73
gi|46249393 ras homolog gene family, member G [Homo sapiens]          270   9e-73
gi|50263042 ras-like protein TC10 [Homo sapiens]                      240   7e-64
gi|16903164 ras homolog gene family, member J [Homo sapiens]          228   4e-60
gi|10835049 ras homolog gene family, member A [Homo sapiens]          207   4e-54
gi|11034843 ras homolog gene family, member U [Homo sapiens]          207   7e-54
gi|111494251 ras homolog gene family, member C precursor [Homo s...   206   1e-53
gi|111494248 ras homolog gene family, member C precursor [Homo s...   206   1e-53
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   206   1e-53
gi|4757764 ras homolog gene family, member B [Homo sapiens]           200   6e-52
gi|229577148 ras homolog gene family, member V [Homo sapiens]         197   5e-51
gi|7656900 ras homolog D [Homo sapiens]                               192   2e-49
gi|38016957 ras homolog gene family, member F [Homo sapiens]          184   5e-47
gi|4885581 Rho family GTPase 2 [Homo sapiens]                         160   6e-40
gi|4885069 ras homolog gene family, member E [Homo sapiens]           159   2e-39
gi|4757770 ras homolog gene family, member H [Homo sapiens]           147   6e-36
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                    136   1e-32
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...   120   8e-28
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...   120   8e-28
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...   120   8e-28
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]        119   1e-27
gi|5902050 Ras-like without CAAX 1 [Homo sapiens]                      82   4e-16
gi|7705963 RAB9B, member RAS oncogene family [Homo sapiens]            81   6e-16
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]        80   1e-15

>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  434 bits (1116), Expect = e-122
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV
Sbjct: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
           RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT
Sbjct: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
           QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
Sbjct: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  384 bits (987), Expect = e-107
 Identities = 192/211 (90%), Positives = 192/211 (90%), Gaps = 19/211 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QEDYDRLRPLSYPQT                   DVFLICFSLVSPASFENVRAKWYPEV
Sbjct: 61  QEDYDRLRPLSYPQT-------------------DVFLICFSLVSPASFENVRAKWYPEV 101

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
           RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT
Sbjct: 102 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 161

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
           QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
Sbjct: 162 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  363 bits (931), Expect = e-101
 Identities = 178/208 (85%), Positives = 186/208 (89%), Gaps = 19/208 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QEDYDRLRPLSYPQT                   DVFLICFSLVSPASFENVRAKWYPEV
Sbjct: 61  QEDYDRLRPLSYPQT-------------------DVFLICFSLVSPASFENVRAKWYPEV 101

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
           RHHCP+TPI+LVGTKLDLRDDKDTIE+L++KKL PITYPQGLAMA+EIG+VKYLECSALT
Sbjct: 102 RHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALT 161

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKC 208
           QRGLKTVFDEAIRAVLCPPPVKK  +KC
Sbjct: 162 QRGLKTVFDEAIRAVLCPPPVKKPGKKC 189


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  357 bits (916), Expect = 4e-99
 Identities = 177/211 (83%), Positives = 185/211 (87%), Gaps = 19/211 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QEDYDRLRPLSYPQT                   DVFLICFSLVSPAS+ENVRAKW+PEV
Sbjct: 61  QEDYDRLRPLSYPQT-------------------DVFLICFSLVSPASYENVRAKWFPEV 101

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
           RHHCP+TPIILVGTKLDLRDDKDTIEKLKEKKL PITYPQGLA+AKEI +VKYLECSALT
Sbjct: 102 RHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALT 161

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
           QRGLKTVFDEAIRAVLCP P +++KR C LL
Sbjct: 162 QRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  274 bits (700), Expect = 5e-74
 Identities = 135/211 (63%), Positives = 158/211 (74%), Gaps = 20/211 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+ G+P  LGL+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QEDYDRLRPLSYPQT                   DVFL+CFS+VSP+SFENV+ KW PE+
Sbjct: 61  QEDYDRLRPLSYPQT-------------------DVFLVCFSVVSPSSFENVKEKWVPEI 101

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
            HHCP TP +LVGT++DLRDD  TIEKL + K  PIT      +A+++ AVKY+ECSALT
Sbjct: 102 THHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALT 161

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
           Q+GLK VFDEAI A L  PP  K+ R+C+LL
Sbjct: 162 QKGLKNVFDEAILAAL-EPPEPKKSRRCVLL 191


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  274 bits (700), Expect = 5e-74
 Identities = 135/211 (63%), Positives = 158/211 (74%), Gaps = 20/211 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+ G+P  LGL+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QEDYDRLRPLSYPQT                   DVFL+CFS+VSP+SFENV+ KW PE+
Sbjct: 61  QEDYDRLRPLSYPQT-------------------DVFLVCFSVVSPSSFENVKEKWVPEI 101

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
            HHCP TP +LVGT++DLRDD  TIEKL + K  PIT      +A+++ AVKY+ECSALT
Sbjct: 102 THHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALT 161

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
           Q+GLK VFDEAI A L  PP  K+ R+C+LL
Sbjct: 162 QKGLKNVFDEAILAAL-EPPEPKKSRRCVLL 191


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  272 bits (696), Expect = 1e-73
 Identities = 132/209 (63%), Positives = 156/209 (74%), Gaps = 19/209 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+ G+P  LGL+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QEDYDRLRPLSYPQT                   DVFL+CFS+VSP+SFENV+ KW PE+
Sbjct: 61  QEDYDRLRPLSYPQT-------------------DVFLVCFSVVSPSSFENVKEKWVPEI 101

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
            HHCP TP +LVGT++DLRDD  TIEKL + K  PIT      +A+++ AVKY+ECSALT
Sbjct: 102 THHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALT 161

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCL 209
           QRGLK VFDEAI A L PP  + +++ C+
Sbjct: 162 QRGLKNVFDEAILAALEPPETQPKRKCCI 190


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  270 bits (689), Expect = 9e-73
 Identities = 138/211 (65%), Positives = 158/211 (74%), Gaps = 20/211 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VDG+ VNL LWDTAG
Sbjct: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           QE+YDRLR LSYPQT                   +VF+ICFS+ SP S+ENVR KW+PEV
Sbjct: 61  QEEYDRLRTLSYPQT-------------------NVFVICFSIASPPSYENVRHKWHPEV 101

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
            HHCP+ PI+LVGTK DLR   DT+ +LKE+   PIT  QG A+AK+I AV+YLECSAL 
Sbjct: 102 CHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQ 161

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
           Q G+K VF EA+RAVL P P+ KR R C+LL
Sbjct: 162 QDGVKEVFAEAVRAVLNPTPI-KRGRSCILL 191


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  240 bits (612), Expect = 7e-64
 Identities = 121/203 (59%), Positives = 148/203 (72%), Gaps = 21/203 (10%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQED 63
           +KCVVVGDGAVGKTCLL+SY  +AFP EY+PTVFD+Y+ +V V GK   LGL+DTAGQED
Sbjct: 10  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQED 69

Query: 64  YDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHH 123
           YDRLRPLSYP T                   DVFLICFS+V+PASF+NV+ +W PE++ +
Sbjct: 70  YDRLRPLSYPMT-------------------DVFLICFSVVNPASFQNVKEEWVPELKEY 110

Query: 124 CPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRG 183
            PN P +L+GT++DLRDD  T+ +L + K  PI   QG  +AKEIGA  Y+ECSALTQ+G
Sbjct: 111 APNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKG 170

Query: 184 LKTVFDEAIRAVLCPP--PVKKR 204
           LKTVFDEAI A+L P    VKKR
Sbjct: 171 LKTVFDEAIIAILTPKKHTVKKR 193


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  228 bits (580), Expect = 4e-60
 Identities = 114/205 (55%), Positives = 145/205 (70%), Gaps = 22/205 (10%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQED 63
           +KCVVVGDGAVGKTCLL+SY  +AFP EY+PTVFD+Y+  V V GK   LGL+DTAGQED
Sbjct: 22  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQED 81

Query: 64  YDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHH 123
           Y++LRPLSYP T                   DVFLICFS+V+PAS+ NV+ +W PE++  
Sbjct: 82  YNQLRPLSYPNT-------------------DVFLICFSVVNPASYHNVQEEWVPELKDC 122

Query: 124 CPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRG 183
            P+ P +L+GT++DLRDD  T+ +L   K  P+TY  G+ +AK IGA  YLECSALTQ+G
Sbjct: 123 MPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKG 182

Query: 184 LKTVFDEAIRAVLCPPPVKKRKRKC 208
           LK VFDEAI  +  P   KK+K++C
Sbjct: 183 LKAVFDEAILTIFHP---KKKKKRC 204


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  207 bits (528), Expect = 4e-54
 Identities = 110/207 (53%), Positives = 134/207 (64%), Gaps = 20/207 (9%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
           DRLRPLSYP T                   DV L+CFS+ SP S EN+  KW PEV+H C
Sbjct: 67  DRLRPLSYPDT-------------------DVILMCFSIDSPDSLENIPEKWTPEVKHFC 107

Query: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGL 184
           PN PIILVG K DLR+D+ T  +L + K  P+   +G  MA  IGA  Y+ECSA T+ G+
Sbjct: 108 PNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGV 167

Query: 185 KTVFDEAIRAVLCPPPVKKRKRKCLLL 211
           + VF+ A RA L     KK K  CL+L
Sbjct: 168 REVFEMATRAALQARRGKK-KSGCLVL 193


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  207 bits (526), Expect = 7e-54
 Identities = 104/193 (53%), Positives = 131/193 (67%), Gaps = 19/193 (9%)

Query: 2   QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQ 61
           + +KCV+VGDGAVGKT L++SYTTN +P EYIPT FDN+SA V VDG+PV L L DTAGQ
Sbjct: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107

Query: 62  EDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVR 121
           +++D+LRPL Y  T                   D+FL+CFS+VSP+SF+NV  KW PE+R
Sbjct: 108 DEFDKLRPLCYTNT-------------------DIFLLCFSVVSPSSFQNVSEKWVPEIR 148

Query: 122 HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQ 181
            HCP  PIILVGT+ DLR+D   + +L + K  P+        A+EI A  Y+ECSALTQ
Sbjct: 149 CHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQ 208

Query: 182 RGLKTVFDEAIRA 194
           + LK VFD AI A
Sbjct: 209 KNLKEVFDAAIVA 221


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  206 bits (524), Expect = 1e-53
 Identities = 108/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
           DRLRPLSYP T                   DV L+CFS+ SP S EN+  KW PEV+H C
Sbjct: 67  DRLRPLSYPDT-------------------DVILMCFSIDSPDSLENIPEKWTPEVKHFC 107

Query: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGL 184
           PN PIILVG K DLR D+ T  +L + K  P+   +G  MA  I A  YLECSA T+ G+
Sbjct: 108 PNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGV 167

Query: 185 KTVFDEAIRAVLCPPPVKKRKRK 207
           + VF+ A RA L    V+K KR+
Sbjct: 168 REVFEMATRAGL---QVRKNKRR 187


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  206 bits (524), Expect = 1e-53
 Identities = 108/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
           DRLRPLSYP T                   DV L+CFS+ SP S EN+  KW PEV+H C
Sbjct: 67  DRLRPLSYPDT-------------------DVILMCFSIDSPDSLENIPEKWTPEVKHFC 107

Query: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGL 184
           PN PIILVG K DLR D+ T  +L + K  P+   +G  MA  I A  YLECSA T+ G+
Sbjct: 108 PNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGV 167

Query: 185 KTVFDEAIRAVLCPPPVKKRKRK 207
           + VF+ A RA L    V+K KR+
Sbjct: 168 REVFEMATRAGL---QVRKNKRR 187


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  206 bits (524), Expect = 1e-53
 Identities = 108/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
           DRLRPLSYP T                   DV L+CFS+ SP S EN+  KW PEV+H C
Sbjct: 67  DRLRPLSYPDT-------------------DVILMCFSIDSPDSLENIPEKWTPEVKHFC 107

Query: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGL 184
           PN PIILVG K DLR D+ T  +L + K  P+   +G  MA  I A  YLECSA T+ G+
Sbjct: 108 PNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGV 167

Query: 185 KTVFDEAIRAVLCPPPVKKRKRK 207
           + VF+ A RA L    V+K KR+
Sbjct: 168 REVFEMATRAGL---QVRKNKRR 187


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  200 bits (509), Expect = 6e-52
 Identities = 104/192 (54%), Positives = 122/192 (63%), Gaps = 19/192 (9%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K VVVGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 7   KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
           DRLRPLSYP T                   DV L+CFS+ SP S EN+  KW PEV+H C
Sbjct: 67  DRLRPLSYPDT-------------------DVILMCFSVDSPDSLENIPEKWVPEVKHFC 107

Query: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGL 184
           PN PIILV  K DLR D+    +L   K  P+    G AMA  I A  YLECSA T+ G+
Sbjct: 108 PNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGV 167

Query: 185 KTVFDEAIRAVL 196
           + VF+ A RA L
Sbjct: 168 REVFETATRAAL 179


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  197 bits (501), Expect = 5e-51
 Identities = 98/194 (50%), Positives = 127/194 (65%), Gaps = 20/194 (10%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQED 63
           IKCV+VGDGAVGK+ L++SYT N +P  Y PT  D +S  V+VDG PV + LWDTAGQED
Sbjct: 32  IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQED 91

Query: 64  YDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHH 123
           +DRLR L YP T                   DVFL CFS+V P+SF+N+  KW PE+R H
Sbjct: 92  FDRLRSLCYPDT-------------------DVFLACFSVVQPSSFQNITEKWLPEIRTH 132

Query: 124 CPNTPIILVGTKLDLRDDKDTIEKLKE-KKLTPITYPQGLAMAKEIGAVKYLECSALTQR 182
            P  P++LVGT+ DLRDD + + +L +  +  P+  PQ   +A++I A  YLECSALTQ+
Sbjct: 133 NPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQK 192

Query: 183 GLKTVFDEAIRAVL 196
            LK VFD AI + +
Sbjct: 193 NLKEVFDSAILSAI 206


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  192 bits (488), Expect = 2e-49
 Identities = 94/196 (47%), Positives = 119/196 (60%), Gaps = 19/196 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           ++++K V+VGDG  GKT LL+ +   AFP  Y PTVF+ Y  N+ V GKPV+L +WDTAG
Sbjct: 15  VRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAG 74

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
           Q+DYDRLRPL YP                    A V L+CF + SP SF+N+  +WYPEV
Sbjct: 75  QDDYDRLRPLFYPD-------------------ASVLLLCFDVTSPNSFDNIFNRWYPEV 115

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
            H C   PII+VG K DLR DK  + KL+   L P+TY +G  MA+ +GAV YLECSA  
Sbjct: 116 NHFCKKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARL 175

Query: 181 QRGLKTVFDEAIRAVL 196
              +  VF EA    L
Sbjct: 176 HDNVHAVFQEAAEVAL 191


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score =  184 bits (467), Expect = 5e-47
 Identities = 95/211 (45%), Positives = 130/211 (61%), Gaps = 22/211 (10%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQED 63
           +K V+VGDG  GKT LL+ Y+  +FP  Y P+VF+ Y+A+V V  K V L L+DTAGQED
Sbjct: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79

Query: 64  YDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHH 123
           YDRLRPLSY  T                    + LIC+ +++P S++NV  KW+PEV H 
Sbjct: 80  YDRLRPLSYQNT-------------------HLVLICYDVMNPTSYDNVLIKWFPEVTHF 120

Query: 124 CPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRG 183
           C   P++L+G K DLR DK+ + KL+  +L PITY QGL+  ++I A  YLECSA  +  
Sbjct: 121 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN 180

Query: 184 LKTVFDEAIRAVLC---PPPVKKRKRKCLLL 211
           ++ VF EA +  L        +K++R CLLL
Sbjct: 181 VEDVFREAAKVALSALKKAQRQKKRRLCLLL 211


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score =  160 bits (406), Expect = 6e-40
 Identities = 78/193 (40%), Positives = 117/193 (60%), Gaps = 20/193 (10%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K VVVGD   GKT LL  +  +A+PG Y+PTVF+NY+A+  +D + + L +WDT+G   Y
Sbjct: 9   KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYY 68

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
           D +RPL+YP +                   D  LICF +  P + ++V  KW  E +  C
Sbjct: 69  DNVRPLAYPDS-------------------DAVLICFDISRPETLDSVLKKWQGETQEFC 109

Query: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSA-LTQRG 183
           PN  ++LVG KLD+R D  T+ +L +++L P+T+ QG  +AK++GAV Y+ECS+  ++R 
Sbjct: 110 PNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERS 169

Query: 184 LKTVFDEAIRAVL 196
           ++ VF  A  A L
Sbjct: 170 VRDVFHVATVASL 182


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score =  159 bits (401), Expect = 2e-39
 Identities = 82/196 (41%), Positives = 115/196 (58%), Gaps = 22/196 (11%)

Query: 2   QAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTA 59
           Q +KC  VVVGD   GKT LL  +  + FP  Y+PTVF+NY+A+  +D + + L LWDT+
Sbjct: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79

Query: 60  GQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPE 119
           G   YD +RPLSYP +                   D  LICF +  P + ++V  KW  E
Sbjct: 80  GSPYYDNVRPLSYPDS-------------------DAVLICFDISRPETLDSVLKKWKGE 120

Query: 120 VRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL 179
           ++  CPNT ++LVG K DLR D  T+ +L   + TP++Y QG  MAK+IGA  Y+ECSAL
Sbjct: 121 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 180

Query: 180 -TQRGLKTVFDEAIRA 194
            ++  ++ +F  A  A
Sbjct: 181 QSENSVRDIFHVATLA 196


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score =  147 bits (371), Expect = 6e-36
 Identities = 77/206 (37%), Positives = 122/206 (59%), Gaps = 26/206 (12%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           + +IKCV+VGD AVGKT LL+ +T+  FP  Y PTV++N   +V +DG  ++LGLWDTAG
Sbjct: 2   LSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAG 61

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
            + +  +RPLSY Q                   ADV L+C+S+ +  SF N++ KW  E+
Sbjct: 62  NDAFRSIRPLSYQQ-------------------ADVVLMCYSVANHNSFLNLKNKWIGEI 102

Query: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180
           R + P TP+++V T+ D R+       +   + + +   +G  +A+++ A  YLECSAL+
Sbjct: 103 RSNLPCTPVLVVATQTDQRE-------MGPHRASCVNAMEGKKLAQDVRAKGYLECSALS 155

Query: 181 QRGLKTVFDEAIRAVLCPPPVKKRKR 206
            RG++ VF+ A+R  +     + R+R
Sbjct: 156 NRGVQQVFECAVRTAVNQARRRNRRR 181


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score =  136 bits (342), Expect = 1e-32
 Identities = 74/204 (36%), Positives = 115/204 (56%), Gaps = 25/204 (12%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K V+VGD   GKT +L     + +P  Y+PTVF+NY+A +  + + V L LWDT+G   Y
Sbjct: 15  KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
           D +RPL Y  +                   D  L+CF +  P + ++   KW  E+  +C
Sbjct: 75  DNVRPLCYSDS-------------------DAVLLCFDISRPETVDSALKKWRTEILDYC 115

Query: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT-QRG 183
           P+T ++L+G K DLR D  T+ +L  +K  PI+Y QG A+AK++GA  YLE SA T ++ 
Sbjct: 116 PSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKS 175

Query: 184 LKTVFDEAIRAVLC---PPPVKKR 204
           + ++F  A  ++LC   P P+ ++
Sbjct: 176 IHSIFRTA--SMLCLNKPSPLPQK 197


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score =  120 bits (301), Expect = 8e-28
 Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 12  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71

Query: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104
           +VD   V+L LWDT G    DR             YG+           +DV ++CFS+ 
Sbjct: 72  VVDDVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 110

Query: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------T 157
           +P S  +V+  WYPE++H CP  P+ILVG +LDLR  D + + + +     PI       
Sbjct: 111 NPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILP 170

Query: 158 YPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196
             +G  +AKE+G + Y E S + Q G+K VFD AIRA L
Sbjct: 171 PEKGREVAKELG-IPYYETSVVAQFGIKDVFDNAIRAAL 208


>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score =  120 bits (301), Expect = 8e-28
 Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78

Query: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104
           +VD   V+L LWDT G    DR             YG+           +DV ++CFS+ 
Sbjct: 79  VVDDVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 117

Query: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------T 157
           +P S  +V+  WYPE++H CP  P+ILVG +LDLR  D + + + +     PI       
Sbjct: 118 NPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILP 177

Query: 158 YPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196
             +G  +AKE+G + Y E S + Q G+K VFD AIRA L
Sbjct: 178 PEKGREVAKELG-IPYYETSVVAQFGIKDVFDNAIRAAL 215


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score =  120 bits (301), Expect = 8e-28
 Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 34  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93

Query: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104
           +VD   V+L LWDT G    DR             YG+           +DV ++CFS+ 
Sbjct: 94  VVDDVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 132

Query: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------T 157
           +P S  +V+  WYPE++H CP  P+ILVG +LDLR  D + + + +     PI       
Sbjct: 133 NPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILP 192

Query: 158 YPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196
             +G  +AKE+G + Y E S + Q G+K VFD AIRA L
Sbjct: 193 PEKGREVAKELG-IPYYETSVVAQFGIKDVFDNAIRAAL 230


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score =  119 bits (299), Expect = 1e-27
 Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   N    +Y      +PTV+  D Y         +  
Sbjct: 12  VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71

Query: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104
           +VD   V+L LWDT G    DR             YG+           +DV ++CFS+ 
Sbjct: 72  VVDEVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 110

Query: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPITY----- 158
           +P S  +V++ WYPE++H CP TP+ILVG +LDLR  D + + + +     PI       
Sbjct: 111 NPNSLNHVKSMWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILP 170

Query: 159 -PQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196
             +G  +AKE+G + Y E S   Q G+K VFD AIRA L
Sbjct: 171 PEKGREVAKELG-LPYYETSVFDQFGIKDVFDNAIRAAL 208


>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
          Length = 219

 Score = 81.6 bits (200), Expect = 4e-16
 Identities = 55/192 (28%), Positives = 93/192 (48%), Gaps = 33/192 (17%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K V++G G VGK+ + + + ++ FP ++ PT+ D Y   + +D +P NL + DTAGQ ++
Sbjct: 23  KLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEF 82

Query: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRA-KWYPEVRHH 123
             +R         + Y +            + F+IC+S+    SF  VR  K        
Sbjct: 83  TAMR---------DQYMR----------AGEGFIICYSITDRRSFHEVREFKQLIYRVRR 123

Query: 124 CPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRG 183
             +TP++LVG K DL            K+L  +T  +GLA+A+E  +  + E SA  +  
Sbjct: 124 TDDTPVVLVGNKSDL------------KQLRQVTKEEGLALAREF-SCPFFETSAAYRYY 170

Query: 184 LKTVFDEAIRAV 195
           +  VF   +R +
Sbjct: 171 IDDVFHALVREI 182


>gi|7705963 RAB9B, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score = 81.3 bits (199), Expect = 6e-16
 Identities = 64/213 (30%), Positives = 99/213 (46%), Gaps = 42/213 (19%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGKPVNLGLWDTAGQE 62
           +K +++GDG VGK+ L+  Y TN F  +   T+  +  + ++ VDG+ V L +WDTAGQE
Sbjct: 8   LKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQE 67

Query: 63  DYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRH 122
            +  LR   Y              RG     AD  L+ FS+    SFEN+   W  E  +
Sbjct: 68  RFKSLRTPFY--------------RG-----ADCCLLTFSVDDRQSFENL-GNWQKEFIY 107

Query: 123 HC-----PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECS 177
           +       + P +++G K+D  D + T E+ +                 E G   YLE S
Sbjct: 108 YADVKDPEHFPFVVLGNKVDKEDRQVTTEEAQ-------------TWCMENGDYPYLETS 154

Query: 178 ALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLL 210
           A     +   F+EA+R VL    V+++   C+L
Sbjct: 155 AKDDTNVTVAFEEAVRQVLA---VEEQLEHCML 184


>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
          Length = 183

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 55/194 (28%), Positives = 93/194 (47%), Gaps = 33/194 (17%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           M+  K VV+G G VGK+ L + + T +F  +Y PT+ D Y   + VD  P  L + DTAG
Sbjct: 1   MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60

Query: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120
            E +  +R L      G                   F++ +SLV+  SF++++      +
Sbjct: 61  TEQFASMRDLYIKNGQG-------------------FILVYSLVNQQSFQDIKPMRDQII 101

Query: 121 R-HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL 179
           R       P+ILVG K+DL  +++            ++Y +G A+A+E  +  ++E SA 
Sbjct: 102 RVKRYERVPMILVGNKVDLEGERE------------VSYGEGKALAEE-WSCPFMETSAK 148

Query: 180 TQRGLKTVFDEAIR 193
            +  +  +F E +R
Sbjct: 149 NKASVDELFAEIVR 162


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,632,300
Number of Sequences: 37866
Number of extensions: 370454
Number of successful extensions: 1152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 770
Number of HSP's gapped (non-prelim): 202
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.