Guide to the Human Genome
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Search of human proteins with 9558729

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9558729 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 1 [Homo sapiens]
         (639 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9558729 golgi associated, gamma adaptin ear containing, ARF b...  1270   0.0  
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ...   781   0.0  
gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo...   635   0.0  
gi|14719400 ADP-ribosylation factor binding protein 3 isoform sh...   557   e-158
gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]   519   e-147
gi|239758145 PREDICTED: similar to ADP-ribosylation factor bindi...   144   2e-34
gi|48527954 golgi associated, gamma adaptin ear containing, ARF ...   144   2e-34
gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]           111   2e-24
gi|209180457 target of myb1 isoform 2 [Homo sapiens]                   99   1e-20
gi|4885637 target of myb1 isoform 1 [Homo sapiens]                     99   1e-20
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i...    92   1e-18
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i...    92   1e-18
gi|209180448 target of myb1 isoform 3 [Homo sapiens]                   90   7e-18
gi|191252812 target of myb1-like 1 [Homo sapiens]                      83   7e-16
gi|209180450 target of myb1 isoform 4 [Homo sapiens]                   75   1e-13
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su...    69   2e-11
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H...    66   1e-10
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]        64   3e-10
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]      61   4e-09
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                60   8e-09
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                60   8e-09
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                60   8e-09
gi|75677327 target of myb1-like 2 isoform 1 [Homo sapiens]             54   3e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        45   2e-04
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   44   3e-04
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom...    44   3e-04
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ...    44   3e-04
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              44   5e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   6e-04
gi|239508973 PREDICTED: similar to Mucin-3A [Homo sapiens]             43   8e-04

>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 1270 bits (3286), Expect = 0.0
 Identities = 639/639 (100%), Positives = 639/639 (100%)

Query: 1   MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
           MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
Sbjct: 1   MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60

Query: 61  WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120
           WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY
Sbjct: 61  WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120

Query: 121 SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR 180
           SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR
Sbjct: 121 SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR 180

Query: 181 LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA 240
           LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA
Sbjct: 181 LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA 240

Query: 241 AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRG 300
           AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRG
Sbjct: 241 AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRG 300

Query: 301 EEVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDE 360
           EEVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDE
Sbjct: 301 EEVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDE 360

Query: 361 LMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL 420
           LMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL
Sbjct: 361 LMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL 420

Query: 421 DDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVS 480
           DDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVS
Sbjct: 421 DDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVS 480

Query: 481 PEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDV 540
           PEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDV
Sbjct: 481 PEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDV 540

Query: 541 LVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLAN 600
           LVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLAN
Sbjct: 541 LVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLAN 600

Query: 601 PQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 639
           PQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL
Sbjct: 601 PQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 639


>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 2 [Homo sapiens]
          Length = 552

 Score =  781 bits (2018), Expect = 0.0
 Identities = 432/641 (67%), Positives = 471/641 (73%), Gaps = 91/641 (14%)

Query: 1   MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
           MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
Sbjct: 1   MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60

Query: 61  WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120
           WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY
Sbjct: 61  WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120

Query: 121 SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR 180
           SWT      V + E  ++ +   ++K    +  D      P  P +  F           
Sbjct: 121 SWT------VGLPEEVKIAEAYQMLKKQGIVKSD------PKLPDDTTFP---------- 158

Query: 181 LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA 240
            L    P          K ++ ED+++ + +++ + +                SH +   
Sbjct: 159 -LPPPRP----------KNVIFEDEEKSKMLARLLKS----------------SHPEDLR 191

Query: 241 AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRG 300
           AA     L+KE+ Q  ++                E +++ + A + +   + L  ++V  
Sbjct: 192 AANK---LIKEMVQEDQKRM--------------EKISKRVNAIEEVNNNVKLLTEMVMS 234

Query: 301 EEVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSAS--VSLLD 358
               G A AGS       L                       ++    +P+     S  +
Sbjct: 235 HS-QGGAAAGSSEDLMKELY----------------------QRCERMRPTLFRLASDTE 271

Query: 359 DELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASS 418
           D   +LGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASS
Sbjct: 272 DNDEALGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASS 331

Query: 419 GLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHT 478
           GLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHT
Sbjct: 332 GLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHT 391

Query: 479 VSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRS 538
           VSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRS
Sbjct: 392 VSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRS 451

Query: 539 DVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLL 598
           DVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLL
Sbjct: 452 DVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLL 511

Query: 599 ANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 639
           ANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL
Sbjct: 512 ANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 552


>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
           [Homo sapiens]
          Length = 723

 Score =  635 bits (1638), Expect = 0.0
 Identities = 367/729 (50%), Positives = 466/729 (63%), Gaps = 105/729 (14%)

Query: 6   EPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ 65
           E E+LE+ +N+ATNP N++ DW  I GFC+Q+N++ EGP +A RLLAHKIQSPQEWEA+Q
Sbjct: 5   EGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ 64

Query: 66  ALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVG 125
           ALTVLE CMK+CG+RFH+EVGKFRFLNELIKVVSPKYLG R SEKVK K++ELLYSWT+ 
Sbjct: 65  ALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMA 124

Query: 126 LPEEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKS 184
           LPEE KI +AY MLK+QGIV+SDP +P D T  P PPPRPKN +F+DEEKSK+LA+LLKS
Sbjct: 125 LPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKS 184

Query: 185 SHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGS 244
            +P+DL+ ANKLIK MV+ED+ R++K++KR++ +EEVNNNV+LL+EM++ +SQ  ++ G 
Sbjct: 185 KNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGD 244

Query: 245 SEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVN 304
            E LMKEL+ +CE  R TLF+LAS+TEDND +L +ILQA+DNL++VIN YK ++ G+ +N
Sbjct: 245 RE-LMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVIN 303

Query: 305 GDATAGSIPGS--------TSALLDLSGLD--------LPPAGTT----YPAMPTRPGEQ 344
           G+    ++P S           L+DL+ LD        L PA T      P +P  P   
Sbjct: 304 GEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPPQAS 363

Query: 345 ASPEQPSAS--------------VSLLDDELMSLGLSDPTP--PSGPSLDGTGWNSFQ-- 386
             P   S+S              +S LD+EL+ LGL+DP P  P   S   + W+  Q  
Sbjct: 364 GPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQRE 423

Query: 387 --------------------------------SSDATEPP------APALAQAPSMES-- 406
                                           SS A  PP       PA   APS  S  
Sbjct: 424 QSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSL 483

Query: 407 ---------RPPAQTSLP-------ASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPT 450
                     P  + ++P        +S L  LD L + L +  +     +       PT
Sbjct: 484 FSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPT 543

Query: 451 PRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPS 510
                R L   S+   SP     S     S  PP+ P      ELSLASI VPLESIKPS
Sbjct: 544 -TTPARPLLPFSTGPGSPLFQPLSFQSQGS--PPKGP------ELSLASIHVPLESIKPS 594

Query: 511 NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKV 570
           + LPVT YD++GFRILFHFA++  PGR DVLVVVVSML+TAP P+++IV Q+AVPK MKV
Sbjct: 595 SALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKV 654

Query: 571 KLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQF 630
           KLQPPSGTEL  F+PI  P+AITQV+LLANP KEKVRLRYKLTF +G+Q   E+G+VDQF
Sbjct: 655 KLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQF 714

Query: 631 PPPETWGSL 639
           PP E WG+L
Sbjct: 715 PPVEQWGNL 723


>gi|14719400 ADP-ribosylation factor binding protein 3 isoform short
           [Homo sapiens]
          Length = 690

 Score =  557 bits (1435), Expect = e-158
 Identities = 338/729 (46%), Positives = 434/729 (59%), Gaps = 138/729 (18%)

Query: 6   EPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ 65
           E E+LE+ +N+ATNP N++ DW  I GFC+Q+N++ EGP +A RLLAHKIQSPQEWEA+Q
Sbjct: 5   EGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ 64

Query: 66  ALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVG 125
           ALT                                 YLG R SEKVK K++ELLYSWT+ 
Sbjct: 65  ALT---------------------------------YLGDRVSEKVKTKVIELLYSWTMA 91

Query: 126 LPEEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKS 184
           LPEE KI +AY MLK+QGIV+SDP +P D T  P PPPRPKN +F+DEEKSK+LA+LLKS
Sbjct: 92  LPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKS 151

Query: 185 SHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGS 244
            +P+DL+ ANKLIK MV+ED+ R++K++KR++ +EEVNNNV+LL+EM++ +SQ  ++ G 
Sbjct: 152 KNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGD 211

Query: 245 SEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVN 304
            E LMKEL+ +CE  R TLF+LAS+TEDND +L +ILQA+DNL++VIN YK ++ G+ +N
Sbjct: 212 RE-LMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVIN 270

Query: 305 GDATAGSIPGS--------TSALLDLSGLD--------LPPAGTT----YPAMPTRPGEQ 344
           G+    ++P S           L+DL+ LD        L PA T      P +P  P   
Sbjct: 271 GEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPPQAS 330

Query: 345 ASPEQPSAS--------------VSLLDDELMSLGLSDPTP--PSGPSLDGTGWNSFQ-- 386
             P   S+S              +S LD+EL+ LGL+DP P  P   S   + W+  Q  
Sbjct: 331 GPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQRE 390

Query: 387 --------------------------------SSDATEPP------APALAQAPSMES-- 406
                                           SS A  PP       PA   APS  S  
Sbjct: 391 QSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSL 450

Query: 407 ---------RPPAQTSLP-------ASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPT 450
                     P  + ++P        +S L  LD L + L +  +     +       PT
Sbjct: 451 FSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPT 510

Query: 451 PRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPS 510
                R L   S+   SP     S     S  PP+ P      ELSLASI VPLESIKPS
Sbjct: 511 -TTPARPLLPFSTGPGSPLFQPLSFQSQGS--PPKGP------ELSLASIHVPLESIKPS 561

Query: 511 NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKV 570
           + LPVT YD++GFRILFHFA++  PGR DVLVVVVSML+TAP P+++IV Q+AVPK MKV
Sbjct: 562 SALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKV 621

Query: 571 KLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQF 630
           KLQPPSGTEL  F+PI  P+AITQV+LLANP KEKVRLRYKLTF +G+Q   E+G+VDQF
Sbjct: 622 KLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQF 681

Query: 631 PPPETWGSL 639
           PP E WG+L
Sbjct: 682 PPVEQWGNL 690


>gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]
          Length = 613

 Score =  519 bits (1337), Expect = e-147
 Identities = 300/632 (47%), Positives = 409/632 (64%), Gaps = 60/632 (9%)

Query: 9   TLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALT 68
           +LE  +N+AT+P   E DW++I  FCEQ+N D  GP  A  LLAHKIQSPQE EA+ ALT
Sbjct: 25  SLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALT 84

Query: 69  VLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPE 128
           VLE CM  CG++FH EV KFRFLNELIKV+SPKYLGS  + KVK +++E+L+SWTV  PE
Sbjct: 85  VLEMCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPE 144

Query: 129 EVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFE-DEEKSKMLARLLKSSHP 187
           ++KI +AYQMLKKQGI+K DPKLP D   P P P PK+ IF+ DEEKSK+L RLLKS+HP
Sbjct: 145 DIKIRDAYQMLKKQGIIKQDPKLPVDKILPPPSPWPKSSIFDADEEKSKLLTRLLKSNHP 204

Query: 188 EDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSED 247
           EDL+AAN+LIK +V+E+Q++ EK+SKRV+A+EEV ++VK+L EM+  + + G A    E 
Sbjct: 205 EDLQAANRLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRPGQAPPDQEA 264

Query: 248 LMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNGDA 307
           L + +Y+RCE++RPTLFRLASDT D+D+ALAEILQAND LTQ + LYKQ++ G    G+ 
Sbjct: 265 L-QVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNR 323

Query: 308 TAGSIPGSTSALLDLSGLDLPPAG--TTYPAMPTRPGEQASPEQPSASVSLLDDELMSLG 365
              S+       + +S +   PAG   T P +     +    +  +   SLL  +L +LG
Sbjct: 324 VTSSLGD-----IPVSRVFQNPAGCMKTCPLIDLEV-DNGPAQMGTVVPSLLHQDLAALG 377

Query: 366 LSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPA------SSG 419
           +SD  P +G     +G N  +                  E R P+ ++LP       S+ 
Sbjct: 378 ISD-APVTGMV---SGQNCCE------------------EKRNPSSSTLPGGGVQNPSAD 415

Query: 420 LDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTV 479
            + LDLL       S  P    + +  Q+  P+      +    + SSP  S        
Sbjct: 416 RNLLDLL-------SAQPAPCPLNYVSQKSVPK------EVPPGTKSSPGWS-----WEA 457

Query: 480 SPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSD 539
            P  P P  Q  P    LA + VPLES+KPS++ P+ VYD++GFRIL HF++   PG  +
Sbjct: 458 GPLAPSPSSQNTP----LAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPE 513

Query: 540 VLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLA 599
           V V++++M+STAPQP+ +I+FQ AVPK M+VKLQP S ++LPAF+P++ P+ I+Q+LLL 
Sbjct: 514 VQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLD 573

Query: 600 NPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFP 631
           NP KE +RLRYKLTF  G Q ++E+G+V  FP
Sbjct: 574 NPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFP 605


>gi|239758145 PREDICTED: similar to ADP-ribosylation factor binding
           protein 2 [Homo sapiens]
          Length = 134

 Score =  144 bits (364), Expect = 2e-34
 Identities = 66/118 (55%), Positives = 94/118 (79%)

Query: 514 PVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQ 573
           P+ VYD++GFRIL HF++   PG  +V V++++M+STAPQP+ +I+FQ AVPK M+VKLQ
Sbjct: 9   PLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQ 68

Query: 574 PPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFP 631
           P S ++LPAF+P++ P+ I+Q+LLL NP KE +RLRYKLTF  G Q ++E+G+V  FP
Sbjct: 69  PASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFP 126


>gi|48527954 golgi associated, gamma adaptin ear containing, ARF
          binding protein 1 isoform 3 [Homo sapiens]
          Length = 89

 Score =  144 bits (364), Expect = 2e-34
 Identities = 69/69 (100%), Positives = 69/69 (100%)

Query: 1  MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
          MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
Sbjct: 1  MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60

Query: 61 WEAIQALTV 69
          WEAIQALTV
Sbjct: 61 WEAIQALTV 69


>gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]
          Length = 507

 Score =  111 bits (277), Expect = 2e-24
 Identities = 109/442 (24%), Positives = 195/442 (44%), Gaps = 34/442 (7%)

Query: 14  INRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLET 72
           + +AT+   +  DW      C+ +NE  EGP  A R L  ++   + + E + ALTVLET
Sbjct: 17  LEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTVLET 76

Query: 73  CMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---PE 128
           C+K+CG RFH  V    F++  L+K++SPK   +     V++K+L L+ +W       P+
Sbjct: 77  CVKNCGHRFHILVANRDFIDSVLVKIISPK---NNPPTIVQDKVLALIQAWADAFRSSPD 133

Query: 129 EVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPR-------PKNVIFEDEEKSKMLARL 181
              +   Y+ LK++G+    P    D   P+  P+       P   +   + + +  A  
Sbjct: 134 LTGVVHIYEELKRKGV--EFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQRTSAGS 191

Query: 182 LKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAA 241
             S  P    A       +        E+I++  + ++ V  N K+++EM ++    G  
Sbjct: 192 YSSPPPAPYSAPQAPALSVTGPITANSEQIARLRSELDVVRGNTKVMSEM-LTEMVPGQE 250

Query: 242 AGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGE 301
             S  +L++EL + C  M+  +  L S    N+E   E+L  ND+L  V   Y++  R  
Sbjct: 251 DSSDLELLQELNRTCRAMQQRIVELISRV-SNEEVTEELLHVNDDLNNVFLRYERFERYR 309

Query: 302 EVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDEL 361
             +G +   +  G  + + + + +DL P       +    G  A P   S+ ++ LD   
Sbjct: 310 --SGRSVQNASNGVLNEVTEDNLIDLGPGSPA--VVSPMVGNTAPPSSLSSQLAGLDLGT 365

Query: 362 MSL-----GLSDPTPPSGPSLDG-TGWNSFQSSDAT---EPPAPALAQAPSMESRPPAQT 412
            S+      L    P  G  +   T  NS      T   E P      A ++++R  +  
Sbjct: 366 ESVSGTLSSLQQCNPRDGFDMFAQTRGNSLAEQRKTVTYEDPQAVGGLASALDNRKQSSE 425

Query: 413 SLPAS--SGLDDLDLLGKTLLQ 432
            +P +  S +DD+++  +T L+
Sbjct: 426 GIPVAQPSVMDDIEVWLRTDLK 447


>gi|209180457 target of myb1 isoform 2 [Homo sapiens]
          Length = 493

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 93/331 (28%), Positives = 151/331 (45%), Gaps = 25/331 (7%)

Query: 13  RINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLE 71
           RI +AT+   +  DWA     C+ +NE  EGP  A R +  +I   + + E + ALTVLE
Sbjct: 16  RIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLE 75

Query: 72  TCMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---P 127
           TC+K+CG RFH  V    F+   L++ + PK   +     V +K+L L+ SW       P
Sbjct: 76  TCVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSP 132

Query: 128 EEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSH 186
           +   +   Y+ L+++G+     + P  D     P   P+  +F  E +S   +    SS 
Sbjct: 133 DLTGVVTIYEDLRRKGL-----EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQ 187

Query: 187 PED--LRAANKLIKEMVQED---QKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAA 241
            ED    AA      ++  D       E+I K  + +E V+ NV++++EM ++      A
Sbjct: 188 QEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEM-LTELVPTQA 246

Query: 242 AGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGE 301
             +  +L++EL + C  M+  +  L      N++   E+L  NDNL  V   +++  R  
Sbjct: 247 EPADLELLQELNRTCRAMQQRVLELIPQIA-NEQLTEELLIVNDNLNNVFLRHERFERFR 305

Query: 302 EVNGDATAGSIPGSTSALLDLSGLDLPPAGT 332
              G  T    P       DL  +   PA T
Sbjct: 306 --TGQTT--KAPSEAEPAADLIDMGPDPAAT 332


>gi|4885637 target of myb1 isoform 1 [Homo sapiens]
          Length = 492

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 93/331 (28%), Positives = 151/331 (45%), Gaps = 25/331 (7%)

Query: 13  RINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLE 71
           RI +AT+   +  DWA     C+ +NE  EGP  A R +  +I   + + E + ALTVLE
Sbjct: 16  RIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLE 75

Query: 72  TCMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---P 127
           TC+K+CG RFH  V    F+   L++ + PK   +     V +K+L L+ SW       P
Sbjct: 76  TCVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSP 132

Query: 128 EEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSH 186
           +   +   Y+ L+++G+     + P  D     P   P+  +F  E +S   +    SS 
Sbjct: 133 DLTGVVTIYEDLRRKGL-----EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQ 187

Query: 187 PED--LRAANKLIKEMVQED---QKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAA 241
            ED    AA      ++  D       E+I K  + +E V+ NV++++EM ++      A
Sbjct: 188 QEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEM-LTELVPTQA 246

Query: 242 AGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGE 301
             +  +L++EL + C  M+  +  L      N++   E+L  NDNL  V   +++  R  
Sbjct: 247 EPADLELLQELNRTCRAMQQRVLELIPQIA-NEQLTEELLIVNDNLNNVFLRHERFERFR 305

Query: 302 EVNGDATAGSIPGSTSALLDLSGLDLPPAGT 332
              G  T    P       DL  +   PA T
Sbjct: 306 --TGQTT--KAPSEAEPAADLIDMGPDPAAT 332


>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
           isoform a [Homo sapiens]
          Length = 825

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)

Query: 386 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 445
           Q++  TEP       AP +E++PP     P S   D LDLLG   +   +P         
Sbjct: 603 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 650

Query: 446 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 505
            +  +    L DL    +   +P+++         P P   PQ   P  L     + PL 
Sbjct: 651 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 700

Query: 506 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 565
           +   + I  +T Y ++G +I F F R        V V+ +   ++    + + VFQ+AVP
Sbjct: 701 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 758

Query: 566 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 625
           K  +++L  PS + +PAFN       ITQV+ + NPQK+++R+R KLT+        ++ 
Sbjct: 759 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 814

Query: 626 DVDQFPPPETW 636
           +V+ F PP++W
Sbjct: 815 EVNNF-PPQSW 824


>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
           isoform b [Homo sapiens]
          Length = 822

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)

Query: 386 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 445
           Q++  TEP       AP +E++PP     P S   D LDLLG   +   +P         
Sbjct: 600 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 647

Query: 446 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 505
            +  +    L DL    +   +P+++         P P   PQ   P  L     + PL 
Sbjct: 648 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 697

Query: 506 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 565
           +   + I  +T Y ++G +I F F R        V V+ +   ++    + + VFQ+AVP
Sbjct: 698 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 755

Query: 566 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 625
           K  +++L  PS + +PAFN       ITQV+ + NPQK+++R+R KLT+        ++ 
Sbjct: 756 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 811

Query: 626 DVDQFPPPETW 636
           +V+ F PP++W
Sbjct: 812 EVNNF-PPQSW 821


>gi|209180448 target of myb1 isoform 3 [Homo sapiens]
          Length = 460

 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 86/310 (27%), Positives = 141/310 (45%), Gaps = 25/310 (8%)

Query: 34  CEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLETCMKSCGKRFHDEVGKFRFLN 92
           C+ +NE  EGP  A R +  +I   + + E + ALTVLETC+K+CG RFH  V    F+ 
Sbjct: 4   CDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVE 63

Query: 93  E-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---PEEVKIAEAYQMLKKQGIVKSD 148
             L++ + PK   +     V +K+L L+ SW       P+   +   Y+ L+++G+    
Sbjct: 64  SVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGL---- 116

Query: 149 PKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPED--LRAANKLIKEMVQED- 204
            + P  D     P   P+  +F  E +S   +    SS  ED    AA      ++  D 
Sbjct: 117 -EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDT 175

Query: 205 --QKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPT 262
                 E+I K  + +E V+ NV++++EM ++      A  +  +L++EL + C  M+  
Sbjct: 176 PIAPTPEQIGKLRSELEMVSGNVRVMSEM-LTELVPTQAEPADLELLQELNRTCRAMQQR 234

Query: 263 LFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNGDATAGSIPGSTSALLDL 322
           +  L      N++   E+L  NDNL  V   +++  R     G  T    P       DL
Sbjct: 235 VLELIPQIA-NEQLTEELLIVNDNLNNVFLRHERFERFR--TGQTT--KAPSEAEPAADL 289

Query: 323 SGLDLPPAGT 332
             +   PA T
Sbjct: 290 IDMGPDPAAT 299


>gi|191252812 target of myb1-like 1 [Homo sapiens]
          Length = 476

 Score = 83.2 bits (204), Expect = 7e-16
 Identities = 101/440 (22%), Positives = 187/440 (42%), Gaps = 51/440 (11%)

Query: 14  INRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ-ALTVLET 72
           I +AT    +  DW      C+ +N   +GP  A + L  +I      + IQ  L++++ 
Sbjct: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78

Query: 73  CMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPEEV- 130
           C+++CG  F   + K  F+ E L+K+++P+Y        ++N+IL  + +W+ G P  V 
Sbjct: 79  CVQNCGPSFQSLIVKKEFVKENLVKLLNPRY---NLPLDIQNRILNFIKTWSQGFPGGVD 135

Query: 131 --KIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPE 188
             ++ E Y  L K+G+               PP         + E ++     + S+ P 
Sbjct: 136 VSEVKEVYLDLVKKGV-------------QFPPSE------AEAETARQETAQISSNPPT 176

Query: 189 DLRAANKLIKEMVQEDQKRM---EKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSS 245
            +  A  L   +  ++       E+I K  + ++ V  NV++++ ++M ++ G       
Sbjct: 177 SVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDI 236

Query: 246 EDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGE---- 301
           E L+++LY+    M+  +  L    E N++   E++Q N++L   I  Y++  R +    
Sbjct: 237 E-LLQKLYKTGREMQERIMDLLVVVE-NEDVTVELIQVNEDLNNAILGYERFTRNQQRIL 294

Query: 302 EVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDEL 361
           E N +    +   S  +      LDL P+    P MP     +A+  + +   + L    
Sbjct: 295 EQNKNQKEATNTTSEPSAPSQDLLDLSPS----PRMP-----RATLGELNTMNNQLSGLN 345

Query: 362 MSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL- 420
            SL  SD T    PSL      +  + + TE P  A   + ++ S       L  S+ + 
Sbjct: 346 FSLPSSDVTNNLKPSLHPQ--MNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVF 403

Query: 421 ---DDLDLLGKTLLQQSLPP 437
                L  +      QSLPP
Sbjct: 404 LQPVSLQTIAAAPSNQSLPP 423



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 19/149 (12%)

Query: 451 PRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPS 510
           PR TL +L   ++  S  + S  S   T + +P   PQ  +   L+L +  +P  + + S
Sbjct: 327 PRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPSLHPQMNL---LALENTEIPPFAQRTS 383

Query: 511 -NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIV--FQSAVPKV 567
            N+     YD              L   + V +  VS+ + A  P    +    S  P +
Sbjct: 384 QNLTSSHAYDNF------------LEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPAM 431

Query: 568 MKVKLQPPSGTELPAFNPIVHPSAITQVL 596
            K  LQPP+  E+  F+P+  P+  T+ +
Sbjct: 432 TKSDLQPPNYYEVMEFDPLA-PAVTTEAI 459


>gi|209180450 target of myb1 isoform 4 [Homo sapiens]
          Length = 447

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 83/322 (25%), Positives = 131/322 (40%), Gaps = 52/322 (16%)

Query: 13  RINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLE 71
           RI +AT+   +  DWA     C+ +NE  EGP  A R +  +I   + + E + ALTVLE
Sbjct: 16  RIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLE 75

Query: 72  TCMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPEEV 130
           TC+K+CG RFH  V    F+   L++ + PK   +     V +K+L L+        + V
Sbjct: 76  TCVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLI--------QTV 124

Query: 131 KIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPEDL 190
             +E        G   S  +       PLP P                  +L    P   
Sbjct: 125 FNSETQSGQDSVGTDSSQQEDSGQHAAPLPAP-----------------PILSGDTP--- 164

Query: 191 RAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSEDLMK 250
                             E+I K  + +E V+ NV++++EM ++      A  +  +L++
Sbjct: 165 -------------IAPTPEQIGKLRSELEMVSGNVRVMSEM-LTELVPTQAEPADLELLQ 210

Query: 251 ELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNGDATAG 310
           EL + C  M+  +  L      N++   E+L  NDNL  V   +++  R     G  T  
Sbjct: 211 ELNRTCRAMQQRVLELIPQIA-NEQLTEELLIVNDNLNNVFLRHERFERFR--TGQTT-- 265

Query: 311 SIPGSTSALLDLSGLDLPPAGT 332
             P       DL  +   PA T
Sbjct: 266 KAPSEAEPAADLIDMGPDPAAT 287


>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
           substrate [Homo sapiens]
          Length = 777

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 8/148 (5%)

Query: 9   TLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALT 68
           T E  +++AT+ L  E DW SI   C+ + +       A   +  K+       A+ AL 
Sbjct: 7   TFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALE 66

Query: 69  VLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPE 128
           V+E+ +K+CG+  HDEV   + + EL        L  +    V+NKIL L+ +W      
Sbjct: 67  VMESVVKNCGQTVHDEVANKQTMEEL-----KDLLKRQVEVNVRNKILYLIQAWAHAFRN 121

Query: 129 EVK---IAEAYQMLKKQGIVKSDPKLPD 153
           E K   + + YQ++K +G V  + K  D
Sbjct: 122 EPKYKVVQDTYQIMKVEGHVFPEFKESD 149


>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
           sapiens]
          Length = 785

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 44/163 (26%), Positives = 83/163 (50%), Gaps = 8/163 (4%)

Query: 475 LLHTVSPEPPRPPQ-QPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDP 533
           LL   S +   PP   P P    +  + +P     P+ I  + V+++ G ++   F R P
Sbjct: 629 LLDGASGDVQHPPHLDPSPGGALVHLLDLPCVPPPPAPIPDLKVFEREGVQLNLSFIRPP 688

Query: 534 LPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAIT 593
                 +L++ ++  + +   + + + Q+AVPK ++++LQ PSG  +PA   +     IT
Sbjct: 689 --ENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGL----PIT 742

Query: 594 QVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETW 636
           Q+  + NP K  +RL+ +LT+    Q+  E+ +V+   P E+W
Sbjct: 743 QLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNL-PVESW 784


>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
          Length = 540

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 9/145 (6%)

Query: 3   PAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWE 62
           P       +  + +AT+ +N   DW  I   C+++ +   GP    R +  ++       
Sbjct: 2   PLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHV 61

Query: 63  AIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSW 122
           A+QALT+L  C+ +CGK FH EV    F +E+  V+      ++   KV  K+  L+  W
Sbjct: 62  AMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVL------NKGHPKVCEKLKALMVEW 115

Query: 123 TVGL---PEEVKIAEAYQMLKKQGI 144
           T      P+   I+   + LK+QG+
Sbjct: 116 TDEFKNDPQLSLISAMIKNLKEQGV 140


>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
          Length = 525

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 53/226 (23%), Positives = 95/226 (42%), Gaps = 27/226 (11%)

Query: 3   PAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWE 62
           P       E  + +ATN  N   DW+ I   C+++     G     + +  ++       
Sbjct: 2   PLFTANPFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHV 61

Query: 63  AIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSW 122
           A+QALT+L  C+ +CGK FH EV    F  E+  V+      ++   KV  K+  L+  W
Sbjct: 62  ALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIK-----NKAHPKVCEKLKSLMVEW 116

Query: 123 TVGL---PEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLA 179
           +      P+   I+   + +K++GI           TFP    +  +   ++   S    
Sbjct: 117 SEEFQKDPQFSLISATIKSMKEEGI-----------TFPPAGSQTVSAAAKNGTSSN--- 162

Query: 180 RLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNV 225
              K+   ED+  A +L   + ++ Q+  E  S   ++  ++NN V
Sbjct: 163 ---KNKEDEDIAKAIEL--SLQEQKQQHTETKSLYPSSEIQLNNKV 203


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 61/217 (28%), Positives = 83/217 (38%), Gaps = 38/217 (17%)

Query: 301 EEVNGDATAGSI-PGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDD 359
           E VN  ++  ++ P ++ A  D +     P+ TT    P  P   A PE  +A       
Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATT----PAPPSSSAPPETTAA------- 191

Query: 360 ELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSG 419
                    P  PS  +      ++   + A  P  PA   AP   S PP  T+ P +  
Sbjct: 192 ---------PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 420 LDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTV 479
                      L  S PPE+  V      PTP  T  D     SS S+P  + T+   T 
Sbjct: 243 ATT-----PAPLSSSAPPETTAV-----PPTPSATTLD----PSSASAPPET-TAAPPTP 287

Query: 480 SPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVT 516
           S   P PP  P P E + A IT P  S  P+ + P T
Sbjct: 288 SATTPAPPSSPAPQETTAAPITTPNSS--PTTLAPDT 322



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 34/136 (25%), Positives = 51/136 (37%), Gaps = 2/136 (1%)

Query: 307 ATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQ-ASPEQPSASVSL-LDDELMSL 364
           AT  + P S++     +    PPA T  P   + P E  A+P  PSA+    L       
Sbjct: 197 ATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPE 256

Query: 365 GLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLD 424
             + P  PS  +LD +  ++   + A  P   A   AP     P   T+ P ++      
Sbjct: 257 TTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPT 316

Query: 425 LLGKTLLQQSLPPESQ 440
            L     + S  P  Q
Sbjct: 317 TLAPDTSETSAAPTHQ 332


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 61/217 (28%), Positives = 83/217 (38%), Gaps = 38/217 (17%)

Query: 301 EEVNGDATAGSI-PGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDD 359
           E VN  ++  ++ P ++ A  D +     P+ TT    P  P   A PE  +A       
Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATT----PAPPSSSAPPETTAA------- 191

Query: 360 ELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSG 419
                    P  PS  +      ++   + A  P  PA   AP   S PP  T+ P +  
Sbjct: 192 ---------PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 420 LDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTV 479
                      L  S PPE+  V      PTP  T  D     SS S+P  + T+   T 
Sbjct: 243 ATT-----PAPLSSSAPPETTAV-----PPTPSATTLD----PSSASAPPET-TAAPPTP 287

Query: 480 SPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVT 516
           S   P PP  P P E + A IT P  S  P+ + P T
Sbjct: 288 SATTPAPPSSPAPQETTAAPITTPNSS--PTTLAPDT 322



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 34/136 (25%), Positives = 51/136 (37%), Gaps = 2/136 (1%)

Query: 307 ATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQ-ASPEQPSASVSL-LDDELMSL 364
           AT  + P S++     +    PPA T  P   + P E  A+P  PSA+    L       
Sbjct: 197 ATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPE 256

Query: 365 GLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLD 424
             + P  PS  +LD +  ++   + A  P   A   AP     P   T+ P ++      
Sbjct: 257 TTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPT 316

Query: 425 LLGKTLLQQSLPPESQ 440
            L     + S  P  Q
Sbjct: 317 TLAPDTSETSAAPTHQ 332


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 61/217 (28%), Positives = 83/217 (38%), Gaps = 38/217 (17%)

Query: 301 EEVNGDATAGSI-PGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDD 359
           E VN  ++  ++ P ++ A  D +     P+ TT    P  P   A PE  +A       
Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATT----PAPPSSSAPPETTAA------- 191

Query: 360 ELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSG 419
                    P  PS  +      ++   + A  P  PA   AP   S PP  T+ P +  
Sbjct: 192 ---------PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 420 LDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTV 479
                      L  S PPE+  V      PTP  T  D     SS S+P  + T+   T 
Sbjct: 243 ATT-----PAPLSSSAPPETTAV-----PPTPSATTLD----PSSASAPPET-TAAPPTP 287

Query: 480 SPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVT 516
           S   P PP  P P E + A IT P  S  P+ + P T
Sbjct: 288 SATTPAPPSSPAPQETTAAPITTPNSS--PTTLAPDT 322



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 34/136 (25%), Positives = 51/136 (37%), Gaps = 2/136 (1%)

Query: 307 ATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQ-ASPEQPSASVSL-LDDELMSL 364
           AT  + P S++     +    PPA T  P   + P E  A+P  PSA+    L       
Sbjct: 197 ATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPE 256

Query: 365 GLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLD 424
             + P  PS  +LD +  ++   + A  P   A   AP     P   T+ P ++      
Sbjct: 257 TTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPT 316

Query: 425 LLGKTLLQQSLPPESQ 440
            L     + S  P  Q
Sbjct: 317 TLAPDTSETSAAPTHQ 332


>gi|75677327 target of myb1-like 2 isoform 1 [Homo sapiens]
          Length = 457

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 87/438 (19%), Positives = 161/438 (36%), Gaps = 76/438 (17%)

Query: 14  INRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLET 72
           + +AT+   +  DW      C+ +NE  EGP  A R L  ++   + + E + ALT    
Sbjct: 17  LEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTAWAD 76

Query: 73  CMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPEEVKI 132
             +S                                                  P+   +
Sbjct: 77  AFRSS-------------------------------------------------PDLTGV 87

Query: 133 AEAYQMLKKQGIVKSDPKLPDDTTFPLPPPR-------PKNVIFEDEEKSKMLARLLKSS 185
              Y+ LK++G+    P    D   P+  P+       P   +   + + +  A    S 
Sbjct: 88  VHIYEELKRKGV--EFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQRTSAGSYSSP 145

Query: 186 HPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSS 245
            P    A       +        E+I++  + ++ V  N K+++EM ++    G    S 
Sbjct: 146 PPAPYSAPQAPALSVTGPITANSEQIARLRSELDVVRGNTKVMSEM-LTEMVPGQEDSSD 204

Query: 246 EDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNG 305
            +L++EL + C  M+  +  L S    N+E   E+L  ND+L  V   Y++  R    +G
Sbjct: 205 LELLQELNRTCRAMQQRIVELISRVS-NEEVTEELLHVNDDLNNVFLRYERFERYR--SG 261

Query: 306 DATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDELMSL- 364
            +   +  G  + + + + +DL P       +    G  A P   S+ ++ LD    S+ 
Sbjct: 262 RSVQNASNGVLNEVTEDNLIDLGPGSPA--VVSPMVGNTAPPSSLSSQLAGLDLGTESVS 319

Query: 365 ----GLSDPTPPSGPSLDG-TGWNSFQSSDAT---EPPAPALAQAPSMESRPPAQTSLPA 416
                L    P  G  +   T  NS      T   E P      A ++++R  +   +P 
Sbjct: 320 GTLSSLQQCNPRDGFDMFAQTRGNSLAEQRKTVTYEDPQAVGGLASALDNRKQSSEGIPV 379

Query: 417 S--SGLDDLDLLGKTLLQ 432
           +  S +DD+++  +T L+
Sbjct: 380 AQPSVMDDIEVWLRTDLK 397


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 51/228 (22%), Positives = 92/228 (40%), Gaps = 34/228 (14%)

Query: 308  TAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSL--LDDELMSLG 365
            ++G++  +TS+  D +G+   PA     +    P      +QPSA  +L    +   S  
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSS 2535

Query: 366  LSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSME-SRPPAQTSLPASSGLDDLD 424
             S  +  S  S   +  +S   S +++    +L   P +   R P+ T  P         
Sbjct: 2536 SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP--------- 2586

Query: 425  LLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSS---------PSSSATSL 475
               K  +++  PPE    + +++  +   +     + SSS SS          SSS++S 
Sbjct: 2587 ---KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643

Query: 476  LHTVSPEPPRP----------PQQPVPTELSLASITVPLESIKPSNIL 513
              + SP P +P          P++P P E    S   P++S++ S  L
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 30/186 (16%)

Query: 307 ATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDELMSLGL 366
           A AG  P   S             GTT    P+ P  + + +QPS+     D +      
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSP--ETATKQPSSPYEDKDKDKKEKSA 347

Query: 367 SDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLL 426
           + P+P           +  +SS   EPPAP    A      P    + P S         
Sbjct: 348 TRPSP-----------SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLS--------- 387

Query: 427 GKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLH--TVSPEPP 484
                Q+ + P S+      + P P+   +  Q+ SS  S PS   T +    + SPE P
Sbjct: 388 -----QEPVNPPSEASPTRDRSP-PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441

Query: 485 RPPQQP 490
           +P   P
Sbjct: 442 KPAPAP 447



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 24/139 (17%)

Query: 309  AGSIPGSTSALLDLSGLDLPPA----GTTYPAMPTRPGEQASPEQPSASVSLLDDELMSL 364
            AGS   +  A   L+   + PA      T P +P    E+ S      S  LLD      
Sbjct: 2353 AGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGR---TSPPLLDRA---- 2405

Query: 365  GLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTS--LPASSGLDD 422
                 TPPS PS       S  +S+    P+  + QAPS    PPAQ     P  S   D
Sbjct: 2406 --RSRTPPSAPS------QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD 2457

Query: 423  LDLLGKTLLQQSLPPESQQ 441
                 + L+ Q+ P    Q
Sbjct: 2458 ---QSRCLIAQTTPVAGSQ 2473



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 38/151 (25%), Positives = 53/151 (35%), Gaps = 12/151 (7%)

Query: 323 SGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDELMSLG--LSDPTPPSGPSLDGT 380
           SG   P A +  P   +R      P+Q S + S       S    +   TPP   S+   
Sbjct: 799 SGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSP 858

Query: 381 GWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQ 440
             N  QS           +  P ++SR P++ S   SS            ++ S PP   
Sbjct: 859 QANE-QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSS---------PPRVKSSTPPRQS 908

Query: 441 QVRWEKQQPTPRLTLRDLQNKSSSCSSPSSS 471
             R    QP  +  +   Q   S  SSPS S
Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSPSPS 939


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 46/170 (27%), Positives = 68/170 (40%), Gaps = 13/170 (7%)

Query: 328  PPAGTTYPAMPTRPGEQASPEQPSASVSLLDDELMSLGLSDPTPPSGPSLDGTGWNSFQS 387
            PP+G   PA PTR  E  +P+ P  +         ++G S P+P +G  L G G   + +
Sbjct: 1128 PPSGARSPA-PTRK-EFGAPKSPGTT------RKDNIGRSQPSPQAG--LAGPGPAGYST 1177

Query: 388  SDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQ 447
            +  T PP   +  AP   +R  A    P S         G T L + L P++     +  
Sbjct: 1178 ARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA-AFPPQSS 1236

Query: 448  QPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRP-PQQPVPTELS 496
             P P   L++      +   P S     L T    PPR      +P+E S
Sbjct: 1237 LPPPAQRLQE-PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEAS 1285



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 29/107 (27%), Positives = 39/107 (36%), Gaps = 30/107 (28%)

Query: 386  QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 445
            QS   +E P P+L   P   SR P++T  P S+    +D    T L Q  P +  +    
Sbjct: 1052 QSPTISEGPVPSL---PIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLE---P 1105

Query: 446  KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVP 492
            K+ P PR                            P  P PPQ+P P
Sbjct: 1106 KRPPPPR------------------------PVAPPTRPAPPQRPPP 1128


>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
           sapiens]
          Length = 1134

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 96/435 (22%), Positives = 168/435 (38%), Gaps = 60/435 (13%)

Query: 168 IFEDEEKSKMLARLLKSSHPEDLRAAN-KLIKEMVQED---QKRMEKISKRVNAIEEVNN 223
           I E++E      R LK  H E  R +N KL++E+ Q +   Q++  ++   V+ +EE+  
Sbjct: 188 IAENQEAKLKKVRALKG-HVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTR 246

Query: 224 NVKLLTE-MVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQ 282
            +++L    + SH    +A    + L KEL  R +  +    +L    E  ++  +E+  
Sbjct: 247 QLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAV 306

Query: 283 ANDNLTQVINLY---KQLVRGEEVNGDATAGSIPG-STSALLDLSGLDLPPAGTTYPAMP 338
            +  + ++ +     K  ++ +E    ++ G++P  + SA   ++ +      +T P MP
Sbjct: 307 MDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMP 366

Query: 339 TRPGEQASPEQPSASVSLLDDELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPAL 398
           +RP     P  P  S+ +   E      + P   SG +    G           P  P  
Sbjct: 367 SRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKG-------SKIHPVGP-- 417

Query: 399 AQAPSMESRPPAQ--TSLPASSG--LDDLDLLGKTLL---QQSLPPESQQVRWEKQQPTP 451
             +PS     P+Q   S+P S+G  LD +D  G+  L   ++ + P S     ++    P
Sbjct: 418 DWSPSNADLFPSQGSASVPQSTGNALDQVD-DGEVPLREKEKKVRPFSMFDAVDQSNAPP 476

Query: 452 RL-TLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPS 510
              TLR  Q+          +  ++     P P +P Q  +P          P   IKP 
Sbjct: 477 SFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP---YFGQTNQPPSDIKPD 533

Query: 511 NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPI---RNIVFQSAVPKV 567
                                    G S  L  VV  + T P+P      ++   ++P V
Sbjct: 534 -------------------------GSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSV 568

Query: 568 -MKVKLQPPSGTELP 581
                L P S  E P
Sbjct: 569 GQDQTLSPGSKQESP 583


>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
           sapiens]
          Length = 1005

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 96/435 (22%), Positives = 168/435 (38%), Gaps = 60/435 (13%)

Query: 168 IFEDEEKSKMLARLLKSSHPEDLRAAN-KLIKEMVQED---QKRMEKISKRVNAIEEVNN 223
           I E++E      R LK  H E  R +N KL++E+ Q +   Q++  ++   V+ +EE+  
Sbjct: 59  IAENQEAKLKKVRALKG-HVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTR 117

Query: 224 NVKLLTE-MVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQ 282
            +++L    + SH    +A    + L KEL  R +  +    +L    E  ++  +E+  
Sbjct: 118 QLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAV 177

Query: 283 ANDNLTQVINLY---KQLVRGEEVNGDATAGSIPG-STSALLDLSGLDLPPAGTTYPAMP 338
            +  + ++ +     K  ++ +E    ++ G++P  + SA   ++ +      +T P MP
Sbjct: 178 MDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMP 237

Query: 339 TRPGEQASPEQPSASVSLLDDELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPAL 398
           +RP     P  P  S+ +   E      + P   SG +    G           P  P  
Sbjct: 238 SRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKG-------SKIHPVGP-- 288

Query: 399 AQAPSMESRPPAQ--TSLPASSG--LDDLDLLGKTLL---QQSLPPESQQVRWEKQQPTP 451
             +PS     P+Q   S+P S+G  LD +D  G+  L   ++ + P S     ++    P
Sbjct: 289 DWSPSNADLFPSQGSASVPQSTGNALDQVD-DGEVPLREKEKKVRPFSMFDAVDQSNAPP 347

Query: 452 RL-TLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPS 510
              TLR  Q+          +  ++     P P +P Q  +P          P   IKP 
Sbjct: 348 SFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP---YFGQTNQPPSDIKPD 404

Query: 511 NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPI---RNIVFQSAVPKV 567
                                    G S  L  VV  + T P+P      ++   ++P V
Sbjct: 405 -------------------------GSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSV 439

Query: 568 -MKVKLQPPSGTELP 581
                L P S  E P
Sbjct: 440 GQDQTLSPGSKQESP 454


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 75/294 (25%), Positives = 97/294 (32%), Gaps = 39/294 (13%)

Query: 327 LPPAGTTYP------AMPTRPGEQASPEQPSASVSLLDDELMSLGLSDPTPP--SGPSLD 378
           LPP G   P      A P +P    S   P ASVS     L S   SDP P   SGP + 
Sbjct: 593 LPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS-SDPAPSDRSGPQIL 651

Query: 379 GTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPE 438
               + F      + PAP         S  PA  +L A + +                P 
Sbjct: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPG--------------PV 697

Query: 439 SQQVRWEKQQPTPRLTLRDLQNKS--SSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELS 496
           S      +  PTP+ TL  LQ     S   SP  S     H   P PP   +  V  E  
Sbjct: 698 STTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYH---PPPPPTKKPEVVVEAP 754

Query: 497 LASITV--PLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQP 554
            AS T   PL+        P    +Q         +    P   +    V S     P  
Sbjct: 755 SASETAEEPLQDPNWPPPPPPAPEEQD-------LSMADFPPPEEAFFSVASPEPAGPSG 807

Query: 555 IRNIVFQSAVPK--VMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKV 606
              +V   A        +++QPP   + P   P   P++     +   PQKE V
Sbjct: 808 SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPV 861



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 59/217 (27%), Positives = 78/217 (35%), Gaps = 40/217 (18%)

Query: 307  ATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDD-ELMSLG 365
            A A S PG  + L         P G +    P R    A    P  + SLL    L S+G
Sbjct: 843  APASSAPGHVAKLPQKE-----PVGCSKGGGPPREDVGA----PLVTPSLLQMVRLRSVG 893

Query: 366  LSD--PTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDL 423
                 PTP  GPS          S  A+  PAP+     ++  +     SL AS GL   
Sbjct: 894  APGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLK---ACSLAASEGLSS- 949

Query: 424  DLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCS---SPSSSATSLLHTVS 480
                    Q + PPE++               R  Q+ +S+ S   S  S    L   VS
Sbjct: 950  -------AQPNGPPEAEP--------------RPPQSPASTASFIFSKGSRKLQLERPVS 988

Query: 481  PEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTV 517
            PE     Q+ +  EL   S   P ++ K S   P  V
Sbjct: 989  PETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 89/330 (26%), Positives = 112/330 (33%), Gaps = 77/330 (23%)

Query: 313 PGSTSALLDLSGLDLPPAGTTYPAMP--TRPGEQASPEQPSASVSLLDDELMSLGLSDPT 370
           P S SA   L  L  PPA     A P  T P  QA P   +     +   L S  L  P 
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404

Query: 371 PP------------SGPSLDGTGWNSF--------------QSSDATEPPAPALAQAP-S 403
            P              P+L  T  +SF               S  A+ PP     QAP S
Sbjct: 405 SPLALSSLQATTSLGSPTLQAT--HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462

Query: 404 MESRPPAQTSL-PASSGLDD------LDLLG-----------KTLLQQSLPPESQQVRWE 445
           + + PP QTSL PA S L        L  L             +L+   L  +S      
Sbjct: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS 522

Query: 446 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLL---HTVSPEPPRP-PQQPVPTELSLASIT 501
            Q P   LT   L+N  S    P  +A++ L   H  +P  P P P Q  P+ L+     
Sbjct: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE 582

Query: 502 VPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQ 561
            P     P    P  +            A  PL G        +S L+T P         
Sbjct: 583 TPSSIATPPPQAPPAL------------ASPPLQGLPS---PPLSPLATPP--------P 619

Query: 562 SAVPKVMKVKLQ-PPSGTELPAFNPIVHPS 590
            A P +    LQ PPS    P  +P+  PS
Sbjct: 620 QAPPXLALPPLQAPPSPPASPPLSPLATPS 649



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 72/287 (25%), Positives = 102/287 (35%), Gaps = 54/287 (18%)

Query: 329 PAGTTYPAMPTRPGEQASPEQPSASVSLLDDELMSLGLSDPTPPSGPSLDGTGWNSFQSS 388
           P    +P+ P   G QA   +P        D   +LG    +P + PS  GT        
Sbjct: 263 PRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320

Query: 389 D-------ATEPPAPALAQ----APSMESRPPAQTSLPASSGLDDLDL-LGKTLLQQSLP 436
           D       AT PP+P LA     AP   S PP+  +LP+             T      P
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380

Query: 437 PESQQV----------RWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSP----- 481
           P  Q +              Q P   L L  LQ  ++S  SP+  AT    T+SP     
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ-ATTSLGSPTLQATHSFLTMSPRQTQA 439

Query: 482 ---EPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPL--PG 536
               P RP   P  +    A +++P      +++ P               A  PL  P 
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSP---------------AVSPLSSPL 484

Query: 537 RSDVLVVVVSMLSTAPQ-PIRNIVFQSAVPKVMKVKLQPPSGTELPA 582
               L  + S+ S +PQ P+ +++     P   +  L PPS    PA
Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMP---PLETQSSLAPPSLQTPPA 528



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 63/212 (29%), Positives = 73/212 (34%), Gaps = 42/212 (19%)

Query: 313 PGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDELMSLGLSDPTP- 371
           P  T + L    L  PPA  T P +   P   A P   +AS  L    L +     P P 
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPS-LAPPPLQTASAPLTTPHLETPPCPAPCPL 569

Query: 372 PSGPSLDGTGWNSFQSSDATEPPA--PALA--------------------QAPSMESRPP 409
            + PS   T      SS AT PP   PALA                    QAP   + PP
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629

Query: 410 AQT--SLPASSGLDDL--------DLLGKTLLQQSL-PPESQQVRWEKQQPTPRLTLRDL 458
            Q   S PAS  L  L        + L   LLQ    PP S  V+     P         
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV---- 685

Query: 459 QNKSSSCSSPSSSATSLLHTVSPEPPRPPQQP 490
              S S + PS +  SL       PP PP  P
Sbjct: 686 ---SPSATPPSQAPPSLAAPPLQVPPSPPASP 714



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 53/208 (25%), Positives = 74/208 (35%), Gaps = 43/208 (20%)

Query: 312 IPGSTSALLDLSGLDLPPAGTTYP-AMPTRPGEQASPEQPSASVSLLDDELMSLGLSDP- 369
           +P S  A   +S    PP     P A P      + P  P  S S      +   L+ P 
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765

Query: 370 --TPPSGPSLDGTGWNSFQSSDATEPP--APALAQAPSMESRPPAQTSLP--------AS 417
              PPS P+       S   S   +PP  AP     P +++ P    S P        AS
Sbjct: 766 LQVPPSPPA-------SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818

Query: 418 SGLDDL--------DLLGKTLLQ-QSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSP 468
             +  L         +L   LLQ    PP S  ++  ++ PTP           +S S P
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP--------GPDTSVSGP 870

Query: 469 SSSATSLLHTVSPEPPRPPQQPVPTELS 496
                 L   ++P PP PP +   + LS
Sbjct: 871 R-----LTLALAPGPPPPPSRSPSSTLS 893


>gi|239508973 PREDICTED: similar to Mucin-3A [Homo sapiens]
          Length = 596

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 49/200 (24%), Positives = 81/200 (40%), Gaps = 31/200 (15%)

Query: 332 TTYPAMPTRPGEQASPEQPS-ASVSLLDDELMSLGLSDPTPPSG--PSLDGTGWNSFQSS 388
           TT  + PT     +SP +   +S  +L  E ++ G+++ TP S    +L  T   S  +S
Sbjct: 273 TTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITNTTPLSTLVTTLPTTISRSTPTS 332

Query: 389 DATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQ 448
           + T P +P      S        T +  S+ +      G    + SLPP S  +   +  
Sbjct: 333 ETTYPTSPTSTVTDST-------TKIAYSTSMT-----GTLSTETSLPPTSSSLPTTETA 380

Query: 449 PTPRLTLRDLQNKSSSCSSPSSSATSLLHTV----------------SPEPPRPPQQPVP 492
            TP   L     + SS S+PS S++++  TV                + E    P    P
Sbjct: 381 TTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHISTSTTAITSHFTTSETAVTPTPVTP 440

Query: 493 TELSLASITVPLESIKPSNI 512
           + LS    T  L ++ PS++
Sbjct: 441 SSLSTDIPTTSLRTLTPSSV 460


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,129,678
Number of Sequences: 37866
Number of extensions: 1569921
Number of successful extensions: 10336
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 648
Number of HSP's that attempted gapping in prelim test: 8491
Number of HSP's gapped (non-prelim): 2229
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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