Search of human proteins with 95147540

Search of human proteins with 95147540

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|95147540 amyloid beta precursor protein-binding, family B,
member 3 isoform b [Homo sapiens]
         (486 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|95147540 amyloid beta precursor protein-binding, family B, me...  1007   0.0  
gi|95147538 amyloid beta precursor protein-binding, family B, me...  1000   0.0  
gi|95147536 amyloid beta precursor protein-binding, family B, me...   998   0.0  
gi|95147542 amyloid beta precursor protein-binding, family B, me...   998   0.0  
gi|50083291 amyloid beta A4 precursor protein-binding, family B,...   374   e-103
gi|4502131 amyloid beta A4 precursor protein-binding, family B, ...   340   1e-93
gi|22035554 amyloid beta A4 precursor protein-binding, family B,...   333   3e-91
gi|197313748 SET domain containing 2 [Homo sapiens]                    42   0.001
gi|222352183 neural precursor cell expressed, developmentally do...    39   0.014
gi|21361472 neural precursor cell expressed, developmentally dow...    39   0.014
gi|222352094 neural precursor cell expressed, developmentally do...    39   0.014
gi|222352092 neural precursor cell expressed, developmentally do...    39   0.014
gi|222352090 neural precursor cell expressed, developmentally do...    39   0.014
gi|222352088 neural precursor cell expressed, developmentally do...    39   0.014
gi|222352086 neural precursor cell expressed, developmentally do...    39   0.014
gi|222352084 neural precursor cell expressed, developmentally do...    39   0.014
gi|222352082 neural precursor cell expressed, developmentally do...    39   0.014
gi|114520609 neural precursor cell expressed, developmentally do...    38   0.018
gi|114520607 neural precursor cell expressed, developmentally do...    38   0.018
gi|40806207 WW domain containing E3 ubiquitin protein ligase 2 i...    35   0.12 
gi|13654239 WW domain containing E3 ubiquitin protein ligase 1 [...    35   0.12 
gi|74027257 polyglutamine binding protein 1 [Homo sapiens]             35   0.20 
gi|74027255 polyglutamine binding protein 1 [Homo sapiens]             35   0.20 
gi|74027253 polyglutamine binding protein 1 [Homo sapiens]             35   0.20 
gi|74027247 polyglutamine binding protein 1 [Homo sapiens]             35   0.20 
gi|5031957 polyglutamine binding protein 1 [Homo sapiens]              35   0.20 
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom...    34   0.34 
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom...    34   0.34 
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom...    34   0.34 
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]         33   0.58 

>gi|95147540 amyloid beta precursor protein-binding, family B,
           member 3 isoform b [Homo sapiens]
          Length = 486

 Score = 1007 bits (2603), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)

Query: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60
           MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT
Sbjct: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60

Query: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120
           WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA
Sbjct: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120

Query: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180
           VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS
Sbjct: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180

Query: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAKAIA 240
           LVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAKAIA
Sbjct: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAKAIA 240

Query: 241 SALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLP 300
           SALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLP
Sbjct: 241 SALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLP 300

Query: 301 VTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVR 360
           VTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVR
Sbjct: 301 VTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVR 360

Query: 361 LVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAA 420
           LVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAA
Sbjct: 361 LVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAA 420

Query: 421 RGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKP 480
           RGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKP
Sbjct: 421 RGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKP 480

Query: 481 SLLHMP 486
           SLLHMP
Sbjct: 481 SLLHMP 486


>gi|95147538 amyloid beta precursor protein-binding, family B,
           member 3 isoform d [Homo sapiens]
          Length = 493

 Score = 1000 bits (2585), Expect = 0.0
 Identities = 486/493 (98%), Positives = 486/493 (98%), Gaps = 7/493 (1%)

Query: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60
           MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT
Sbjct: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60

Query: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120
           WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA
Sbjct: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120

Query: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180
           VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS
Sbjct: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180

Query: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRD-------RDFAFVASDKDSCMLKCHVFCCD 233
           LVNPLDHSLIHCQPLVHIRVWGVGSSKGRD       RDFAFVASDKDSCMLKCHVFCCD
Sbjct: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRDSPISAPARDFAFVASDKDSCMLKCHVFCCD 240

Query: 234 VPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEA 293
           VPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEA
Sbjct: 241 VPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEA 300

Query: 294 LYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEP 353
           LYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEP
Sbjct: 301 LYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEP 360

Query: 354 LWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQK 413
           LWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQK
Sbjct: 361 LWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQK 420

Query: 414 CLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFL 473
           CLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFL
Sbjct: 421 CLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFL 480

Query: 474 DAFRLKPSLLHMP 486
           DAFRLKPSLLHMP
Sbjct: 481 DAFRLKPSLLHMP 493


>gi|95147536 amyloid beta precursor protein-binding, family B,
           member 3 isoform c [Homo sapiens]
          Length = 491

 Score =  998 bits (2580), Expect = 0.0
 Identities = 485/491 (98%), Positives = 485/491 (98%), Gaps = 5/491 (1%)

Query: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60
           MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT
Sbjct: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60

Query: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120
           WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA
Sbjct: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120

Query: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180
           VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS
Sbjct: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180

Query: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRD-----RDFAFVASDKDSCMLKCHVFCCDVP 235
           LVNPLDHSLIHCQPLVHIRVWGVGSSKGR      RDFAFVASDKDSCMLKCHVFCCDVP
Sbjct: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRPISAPARDFAFVASDKDSCMLKCHVFCCDVP 240

Query: 236 AKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALY 295
           AKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALY
Sbjct: 241 AKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALY 300

Query: 296 MGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLW 355
           MGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLW
Sbjct: 301 MGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLW 360

Query: 356 QCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCL 415
           QCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCL
Sbjct: 361 QCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCL 420

Query: 416 VASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDA 475
           VASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDA
Sbjct: 421 VASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDA 480

Query: 476 FRLKPSLLHMP 486
           FRLKPSLLHMP
Sbjct: 481 FRLKPSLLHMP 491


>gi|95147542 amyloid beta precursor protein-binding, family B,
           member 3 isoform a [Homo sapiens]
          Length = 484

 Score =  998 bits (2579), Expect = 0.0
 Identities = 484/486 (99%), Positives = 484/486 (99%), Gaps = 2/486 (0%)

Query: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60
           MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT
Sbjct: 1   MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT 60

Query: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120
           WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA
Sbjct: 61  WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA 120

Query: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180
           VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS
Sbjct: 121 VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS 180

Query: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAKAIA 240
           LVNPLDHSLIHCQPLVHIRVWGVGSSKGRD  FAFVASDKDSCMLKCHVFCCDVPAKAIA
Sbjct: 181 LVNPLDHSLIHCQPLVHIRVWGVGSSKGRD--FAFVASDKDSCMLKCHVFCCDVPAKAIA 238

Query: 241 SALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLP 300
           SALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLP
Sbjct: 239 SALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLP 298

Query: 301 VTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVR 360
           VTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVR
Sbjct: 299 VTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVR 358

Query: 361 LVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAA 420
           LVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAA
Sbjct: 359 LVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAA 418

Query: 421 RGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKP 480
           RGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKP
Sbjct: 419 RGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKP 478

Query: 481 SLLHMP 486
           SLLHMP
Sbjct: 479 SLLHMP 484


>gi|50083291 amyloid beta A4 precursor protein-binding, family B,
           member 2 [Homo sapiens]
          Length = 736

 Score =  374 bits (960), Expect = e-103
 Identities = 203/490 (41%), Positives = 280/490 (57%), Gaps = 49/490 (10%)

Query: 16  DDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPTWELGDAEDPGTGT-- 73
           + D+W DHS + +  LPPGW+++ D AGTYYWH+P+G+TQW+RP     D +    G+  
Sbjct: 277 ETDIWSDHSFQTDPDLPPGWKRVSDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLS 336

Query: 74  ----------EGIWGLRPPKGRSFSSLESSLDRSNSLSWYGG------ESYIQSMEPGAK 117
                     E +         S    E +  R  SL           +S   + +P AK
Sbjct: 337 SVTPSPTPENEDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAK 396

Query: 118 CFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKD 177
           CFAVRSLGWVE+ EEDLAPGKSS+AVNNCI+QL+  ++  +   G WGEG++M +IL+ D
Sbjct: 397 CFAVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILEND 456

Query: 178 AMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAK 237
            +SLV+P+D S++H QP+V IRVWGVG   G  RDFA+VA DKD+ +LKCHVF CD PAK
Sbjct: 457 MLSLVDPMDRSVLHSQPIVSIRVWGVGRDNG--RDFAYVARDKDTRILKCHVFRCDTPAK 514

Query: 238 AIASALHGLCAQILSERVEVSGDASCCSPDPISPE-DLPRQVELLDAVSQAAQKYEALYM 296
           AIA++LH +C++I++ER      A     +  +   D+P Q +     ++  QK+   Y+
Sbjct: 515 AIATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQ-DFPTPKTELVQKFHVQYL 573

Query: 297 GTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQ 356
           G LPV K +GMD+LN AI  L    ++  W+   ++V+D+ +T          EEE L +
Sbjct: 574 GMLPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTV----ISEKNEEEVLVE 629

Query: 357 CPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLV 416
           C VR ++F+GVG+D HTF  I D G Q F+C  FWC+P+AG +SEAVQAACM++YQKCLV
Sbjct: 630 CRVRFLSFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLV 689

Query: 417 ASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAF 476
           A     K                         P P     V     T  KRGV S +D  
Sbjct: 690 ARPPSQKV-----------------------RPPPPPADSVTRRVTTNVKRGVLSLIDTL 726

Query: 477 RLKPSLLHMP 486
           + K  +  MP
Sbjct: 727 KQKRPVTEMP 736


>gi|4502131 amyloid beta A4 precursor protein-binding, family B,
           member 1 isoform E9 [Homo sapiens]
          Length = 710

 Score =  340 bits (873), Expect = 1e-93
 Identities = 179/431 (41%), Positives = 255/431 (59%), Gaps = 37/431 (8%)

Query: 17  DDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRP----------------- 59
           D  W  ++ E ++ LP GW ++ D +GTYYWH+P+G+TQW+ P                 
Sbjct: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300

Query: 60  TWELGDAEDPGTGTEGIW------------GLRPPKGRSFSSLESSLDRSNSLSWYGGES 107
           TW  G A   G      W            GL+ P+  + +    SL     L     + 
Sbjct: 301 TWT-GFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLS-PEPLPQEEEKL 358

Query: 108 YIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPP-DGAWGE 166
             ++  PG KCFAVRSLGWVE+ EE+LAPG+SS+AVNNCI+QL+  ++    P  G WGE
Sbjct: 359 PPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGE 418

Query: 167 GQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLK 226
           G+++L+ L+ + + LV P   +L+H QP++ IRVWGVG   GR+RDFA+VA DK + MLK
Sbjct: 419 GKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRERDFAYVARDKLTQMLK 478

Query: 227 CHVFCCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQ 286
           CHVF C+ PAK IA++LH +C++I++ER       +  S D     D+P QVE     ++
Sbjct: 479 CHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNE 538

Query: 287 AAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAE 346
             QK++  Y+G +PV K +G+DV+N A+ ++ +   R  W P+ +SV+ + +T    Q E
Sbjct: 539 LVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTE 598

Query: 347 ASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAA 406
           A      L +C VR ++F+ VGRD HTF  I   G  SF C  FWC+P+A  LSEAVQAA
Sbjct: 599 A-----VLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAA 653

Query: 407 CMVQYQKCLVA 417
           CM++YQKCL A
Sbjct: 654 CMLRYQKCLDA 664


>gi|22035554 amyloid beta A4 precursor protein-binding, family B,
           member 1 isoform delta E9 [Homo sapiens]
          Length = 708

 Score =  333 bits (853), Expect = 3e-91
 Identities = 178/431 (41%), Positives = 253/431 (58%), Gaps = 39/431 (9%)

Query: 17  DDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRP----------------- 59
           D  W  ++ E ++ LP GW ++ D +GTYYWH+P+G+TQW+ P                 
Sbjct: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300

Query: 60  TWELGDAEDPGTGTEGIW------------GLRPPKGRSFSSLESSLDRSNSLSWYGGES 107
           TW  G A   G      W            GL+ P+  + +    SL     L     + 
Sbjct: 301 TWT-GFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLS-PEPLPQEEEKL 358

Query: 108 YIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPP-DGAWGE 166
             ++  PG KCFAVRSLGWVE+ EE+LAPG+SS+AVNNCI+QL+  ++    P  G WGE
Sbjct: 359 PPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGE 418

Query: 167 GQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLK 226
           G+++L+ L+ + + LV P   +L+H QP++ IRVWGVG   GRD  FA+VA DK + MLK
Sbjct: 419 GKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRD--FAYVARDKLTQMLK 476

Query: 227 CHVFCCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQ 286
           CHVF C+ PAK IA++LH +C++I++ER       +  S D     D+P QVE     ++
Sbjct: 477 CHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNE 536

Query: 287 AAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAE 346
             QK++  Y+G +PV K +G+DV+N A+ ++ +   R  W P+ +SV+ + +T    Q E
Sbjct: 537 LVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTE 596

Query: 347 ASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAA 406
           A      L +C VR ++F+ VGRD HTF  I   G  SF C  FWC+P+A  LSEAVQAA
Sbjct: 597 AV-----LGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAA 651

Query: 407 CMVQYQKCLVA 417
           CM++YQKCL A
Sbjct: 652 CMLRYQKCLDA 662


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 31   LPPGWRKIHDAAGT-YYWHVPSGSTQWQRPTWE 62
            LPP W+   D  G  YY+HV +  TQW  PTWE
Sbjct: 2391 LPPNWKTARDPEGKIYYYHVITRQTQWDPPTWE 2423


>gi|222352183 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 2 [Homo sapiens]
          Length = 854

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 265 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 324

Query: 89  SLES 92
           SL S
Sbjct: 325 SLSS 328



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 74  LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 104


>gi|21361472 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 3 [Homo sapiens]
          Length = 955

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 366 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 425

Query: 89  SLES 92
           SL S
Sbjct: 426 SLSS 429



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 195 LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 225


>gi|222352094 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 6 [Homo sapiens]
          Length = 834

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 245 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 304

Query: 89  SLES 92
           SL S
Sbjct: 305 SLSS 308



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 74  LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 104


>gi|222352092 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 6 [Homo sapiens]
          Length = 834

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 245 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 304

Query: 89  SLES 92
           SL S
Sbjct: 305 SLSS 308



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 74  LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 104


>gi|222352090 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 5 [Homo sapiens]
          Length = 947

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 358 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 417

Query: 89  SLES 92
           SL S
Sbjct: 418 SLSS 421



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 187 LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 217


>gi|222352088 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 4 [Homo sapiens]
          Length = 967

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 378 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 437

Query: 89  SLES 92
           SL S
Sbjct: 438 SLSS 441



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 187 LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 217


>gi|222352086 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 1 [Homo sapiens]
          Length = 975

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 386 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 445

Query: 89  SLES 92
           SL S
Sbjct: 446 SLSS 449



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 195 LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 225


>gi|222352084 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 2 [Homo sapiens]
          Length = 854

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 265 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 324

Query: 89  SLES 92
           SL S
Sbjct: 325 SLSS 328



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 74  LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 104


>gi|222352082 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 2 [Homo sapiens]
          Length = 854

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 30  GLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFS 88
           GLP GW +  DA G TYY +  + +T W RP  +L +    G+ T     L  P+ R   
Sbjct: 265 GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPR 324

Query: 89  SLES 92
           SL S
Sbjct: 325 SLSS 328



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 31  LPPGWR-KIHDAAGTYYWHVPSGSTQWQRPT 60
           LPPGW  K+ +   TYY +  + +TQW RP+
Sbjct: 74  LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPS 104


>gi|114520609 neural precursor cell expressed, developmentally
           down-regulated 4 isoform 1 [Homo sapiens]
          Length = 900

 Score = 38.1 bits (87), Expect = 0.018
 Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 3/41 (7%)

Query: 31  LPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWE--LGDAED 68
           LPPGW +  D  G TYY +  S  TQW+RPT +  L DAE+
Sbjct: 193 LPPGWEERQDILGRTYYVNHESRRTQWKRPTPQDNLTDAEN 233



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query: 25  LEVEAGLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPT 60
           L   +GLPPGW +  D  G +YY    S +T W +PT
Sbjct: 344 LPTSSGLPPGWEEKQDERGRSYYVDHNSRTTTWTKPT 380


>gi|114520607 neural precursor cell expressed, developmentally
           down-regulated 4 isoform 2 [Homo sapiens]
          Length = 1247

 Score = 38.1 bits (87), Expect = 0.018
 Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 3/41 (7%)

Query: 31  LPPGWRKIHDAAG-TYYWHVPSGSTQWQRPTWE--LGDAED 68
           LPPGW +  D  G TYY +  S  TQW+RPT +  L DAE+
Sbjct: 540 LPPGWEERQDILGRTYYVNHESRRTQWKRPTPQDNLTDAEN 580



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query: 25  LEVEAGLPPGWRKIHDAAG-TYYWHVPSGSTQWQRPT 60
           L   +GLPPGW +  D  G +YY    S +T W +PT
Sbjct: 691 LPTSSGLPPGWEEKQDERGRSYYVDHNSRTTTWTKPT 727


>gi|40806207 WW domain containing E3 ubiquitin protein ligase 2
           isoform 1 [Homo sapiens]
          Length = 870

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 4/45 (8%)

Query: 22  DHSLEV---EAGLPPGWRKIHDAAGTYYW-HVPSGSTQWQRPTWE 62
           DH+ +    E  LPPGW K  D  G +Y+    + +T WQRPT E
Sbjct: 320 DHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAE 364



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 13/29 (44%), Positives = 17/29 (58%)

Query: 31  LPPGWRKIHDAAGTYYWHVPSGSTQWQRP 59
           LPPGW K  D    YY +  + +TQW+ P
Sbjct: 407 LPPGWEKRQDNGRVYYVNHNTRTTQWEDP 435


>gi|13654239 WW domain containing E3 ubiquitin protein ligase 1
           [Homo sapiens]
          Length = 922

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 31  LPPGW-RKIHDAAGTYYWHVPSGSTQWQRPTWE 62
           LPPGW R++ D    YY    + +T WQRPT E
Sbjct: 383 LPPGWERRVDDRRRVYYVDHNTRTTTWQRPTME 415


>gi|74027257 polyglutamine binding protein 1 [Homo sapiens]
          Length = 265

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 15/107 (14%)

Query: 10  IILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAG--TYYWHVPSGSTQWQRPTWELGDAE 67
           II  + DDD     +  +E GLPP W K+ D +    YYW+  +    W  P        
Sbjct: 28  IIAEDYDDDPVDYEATRLE-GLPPSWYKVFDPSCGLPYYWNADTDLVSWLSP-------H 79

Query: 68  DPGT-GTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSME 113
           DP +  T+    LR     S +  E  LDRS+  S  G +   +S E
Sbjct: 80  DPNSVVTKSAKKLR----SSNADAEEKLDRSHDKSDRGHDKSDRSHE 122


>gi|74027255 polyglutamine binding protein 1 [Homo sapiens]
          Length = 265

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 15/107 (14%)

Query: 10  IILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAG--TYYWHVPSGSTQWQRPTWELGDAE 67
           II  + DDD     +  +E GLPP W K+ D +    YYW+  +    W  P        
Sbjct: 28  IIAEDYDDDPVDYEATRLE-GLPPSWYKVFDPSCGLPYYWNADTDLVSWLSP-------H 79

Query: 68  DPGT-GTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSME 113
           DP +  T+    LR     S +  E  LDRS+  S  G +   +S E
Sbjct: 80  DPNSVVTKSAKKLR----SSNADAEEKLDRSHDKSDRGHDKSDRSHE 122


>gi|74027253 polyglutamine binding protein 1 [Homo sapiens]
          Length = 265

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 15/107 (14%)

Query: 10  IILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAG--TYYWHVPSGSTQWQRPTWELGDAE 67
           II  + DDD     +  +E GLPP W K+ D +    YYW+  +    W  P        
Sbjct: 28  IIAEDYDDDPVDYEATRLE-GLPPSWYKVFDPSCGLPYYWNADTDLVSWLSP-------H 79

Query: 68  DPGT-GTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSME 113
           DP +  T+    LR     S +  E  LDRS+  S  G +   +S E
Sbjct: 80  DPNSVVTKSAKKLR----SSNADAEEKLDRSHDKSDRGHDKSDRSHE 122


>gi|74027247 polyglutamine binding protein 1 [Homo sapiens]
          Length = 265

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 15/107 (14%)

Query: 10  IILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAG--TYYWHVPSGSTQWQRPTWELGDAE 67
           II  + DDD     +  +E GLPP W K+ D +    YYW+  +    W  P        
Sbjct: 28  IIAEDYDDDPVDYEATRLE-GLPPSWYKVFDPSCGLPYYWNADTDLVSWLSP-------H 79

Query: 68  DPGT-GTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSME 113
           DP +  T+    LR     S +  E  LDRS+  S  G +   +S E
Sbjct: 80  DPNSVVTKSAKKLR----SSNADAEEKLDRSHDKSDRGHDKSDRSHE 122


>gi|5031957 polyglutamine binding protein 1 [Homo sapiens]
          Length = 265

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 15/107 (14%)

Query: 10  IILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAG--TYYWHVPSGSTQWQRPTWELGDAE 67
           II  + DDD     +  +E GLPP W K+ D +    YYW+  +    W  P        
Sbjct: 28  IIAEDYDDDPVDYEATRLE-GLPPSWYKVFDPSCGLPYYWNADTDLVSWLSP-------H 79

Query: 68  DPGT-GTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSME 113
           DP +  T+    LR     S +  E  LDRS+  S  G +   +S E
Sbjct: 80  DPNSVVTKSAKKLR----SSNADAEEKLDRSHDKSDRGHDKSDRSHE 122


>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
           containing 1 isoform b [Homo sapiens]
          Length = 1256

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 4/54 (7%)

Query: 12  LVNCDDDLWGDHS--LEVEAGLPPGWRKIHDAA-GTYYWHVPSGSTQWQRPTWE 62
           L  C+DD  G H+  L+ E  LP GW KI D   G YY    +  TQ++ P  E
Sbjct: 341 LEECEDDE-GVHTEELDSELELPAGWEKIEDPVYGIYYVDHINRKTQYENPVLE 393


>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
           containing 1 isoform c [Homo sapiens]
          Length = 1462

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 4/54 (7%)

Query: 12  LVNCDDDLWGDHS--LEVEAGLPPGWRKIHDAA-GTYYWHVPSGSTQWQRPTWE 62
           L  C+DD  G H+  L+ E  LP GW KI D   G YY    +  TQ++ P  E
Sbjct: 341 LEECEDDE-GVHTEELDSELELPAGWEKIEDPVYGIYYVDHINRKTQYENPVLE 393


>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
           containing 1 isoform a [Homo sapiens]
          Length = 1287

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 4/54 (7%)

Query: 12  LVNCDDDLWGDHS--LEVEAGLPPGWRKIHDAA-GTYYWHVPSGSTQWQRPTWE 62
           L  C+DD  G H+  L+ E  LP GW KI D   G YY    +  TQ++ P  E
Sbjct: 341 LEECEDDE-GVHTEELDSELELPAGWEKIEDPVYGIYYVDHINRKTQYENPVLE 393


>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
          Length = 412

 Score = 33.1 bits (74), Expect = 0.58
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 31 LPPGWRKIHDAAGT-YYWHVPSGSTQWQRPTWELGDAEDPGT 71
          LPPGW+      G  YY +  +  T W+RP+   G    PG+
Sbjct: 15 LPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGS 56


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,729,469
Number of Sequences: 37866
Number of extensions: 1010455
Number of successful extensions: 2774
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 2663
Number of HSP's gapped (non-prelim): 100
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.