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Search of human proteins with 94557290
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94557290 myeloid inhibitory C-type lectin-like receptor
isoform alpha [Homo sapiens]
(265 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94557290 myeloid inhibitory C-type lectin-like receptor isofo... 545 e-155
gi|94557293 myeloid inhibitory C-type lectin-like receptor isofo... 461 e-130
gi|194018501 C-type lectin domain family 12, member B isoform 1 ... 149 3e-36
gi|194018499 C-type lectin domain family 12, member B isoform 2 ... 139 3e-33
gi|37577103 C-type lectin-like receptor-1 [Homo sapiens] 135 3e-32
gi|153252029 C-type lectin domain family 1, member B isoform a [... 94 9e-20
gi|153252048 C-type lectin domain family 1, member B isoform b [... 89 4e-18
gi|4505501 oxidized low density lipoprotein (lectin-like) recept... 88 7e-18
gi|46409326 C-type lectin domain family 9, member A [Homo sapiens] 88 9e-18
gi|7705338 C-type lectin domain family 4, member A isoform 1 [Ho... 75 6e-14
gi|37675373 dendritic cell-associated C-type lectin 1 isoform a ... 73 2e-13
gi|167614498 killer cell lectin-like receptor subfamily D, membe... 70 1e-12
gi|4504889 killer cell lectin-like receptor subfamily D, member ... 70 1e-12
gi|7669499 killer cell lectin-like receptor subfamily D, member ... 70 2e-12
gi|169234653 NKG2-D type II integral membrane protein [Homo sapi... 65 6e-11
gi|37577107 C-type lectin, superfamily member 2 [Homo sapiens] 65 6e-11
gi|7019447 osteoclast inhibitory lectin isoform 1 [Homo sapiens] 63 2e-10
gi|47717094 killer cell lectin-like receptor subfamily C, member... 63 3e-10
gi|4504881 killer cell lectin-like receptor subfamily C, member ... 63 3e-10
gi|75709169 killer cell lectin-like receptor subfamily C, member... 62 4e-10
gi|47717092 killer cell lectin-like receptor subfamily C, member... 62 4e-10
gi|7262384 killer cell lectin-like receptor subfamily C, member ... 62 4e-10
gi|37675375 dendritic cell-associated C-type lectin 1 isoform c ... 62 7e-10
gi|37675379 dendritic cell-associated C-type lectin 1 isoform e ... 61 9e-10
gi|13384604 dendritic cell-associated C-type lectin 1 isoform b ... 61 9e-10
gi|195222725 C-type lectin domain family 2, member A [Homo sapiens] 61 1e-09
gi|38348296 C-type lectin domain family 4, member G [Homo sapiens] 58 7e-09
gi|223278347 C-type lectin domain family 4, member M isoform 9 [... 58 1e-08
gi|223278337 C-type lectin domain family 4, member M isoform 12 ... 58 1e-08
gi|223278335 C-type lectin domain family 4, member M isoform 2 [... 58 1e-08
>gi|94557290 myeloid inhibitory C-type lectin-like receptor isoform
alpha [Homo sapiens]
Length = 265
Score = 545 bits (1404), Expect = e-155
Identities = 265/265 (100%), Positives = 265/265 (100%)
Query: 1 MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL 60
MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL
Sbjct: 1 MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL 60
Query: 61 ASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE 120
ASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE
Sbjct: 61 ASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE 120
Query: 121 LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI 180
LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI
Sbjct: 121 LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI 180
Query: 181 KSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHC 240
KSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHC
Sbjct: 181 KSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHC 240
Query: 241 TYKKRMICEKMANPVQLGSTYFREA 265
TYKKRMICEKMANPVQLGSTYFREA
Sbjct: 241 TYKKRMICEKMANPVQLGSTYFREA 265
>gi|94557293 myeloid inhibitory C-type lectin-like receptor isoform
beta [Homo sapiens]
Length = 232
Score = 461 bits (1185), Expect = e-130
Identities = 231/265 (87%), Positives = 231/265 (87%), Gaps = 33/265 (12%)
Query: 1 MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL 60
MSEEVTYADLQFQNSSEMEKIPEIGKFGEK
Sbjct: 1 MSEEVTYADLQFQNSSEMEKIPEIGKFGEKV----------------------------- 31
Query: 61 ASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE 120
HVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE
Sbjct: 32 ----HVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE 87
Query: 121 LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI 180
LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI
Sbjct: 88 LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI 147
Query: 181 KSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHC 240
KSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHC
Sbjct: 148 KSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHC 207
Query: 241 TYKKRMICEKMANPVQLGSTYFREA 265
TYKKRMICEKMANPVQLGSTYFREA
Sbjct: 208 TYKKRMICEKMANPVQLGSTYFREA 232
>gi|194018501 C-type lectin domain family 12, member B isoform 1
[Homo sapiens]
Length = 276
Score = 149 bits (375), Expect = 3e-36
Identities = 91/271 (33%), Positives = 148/271 (54%), Gaps = 15/271 (5%)
Query: 1 MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL 60
MSEEVTYA L FQ+S+ + ++ PAPS +WR AAL L LCL+LLIGL L
Sbjct: 1 MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTL 60
Query: 61 ASMF---HVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNIS-------NKIRNLSTTL 110
MF + + +K+++LQ ++ Q N+S QL ++ N+S ++I ++
Sbjct: 61 GMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQ 120
Query: 111 QTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSC-YFLSDDVQTWQESKMACAAQNASLL 169
+ +A KLC+EL +H+C PCP+ W W+++SC YF +++ +TW S+ C +N++L+
Sbjct: 121 EQMAIKLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLV 180
Query: 170 KINNKNALEFIKSQS--RSYDYWLGLSPEEDSTRGMRVDNIINS-SAWVIRNAPDLN-NM 225
KI++ +F+ SQ +WLGLS + D + S S + + +N +
Sbjct: 181 KIDSLEEKDFLMSQPLLMFSFFWLGLSWDSSGRSWFWEDGSVPSPSLFSTKELDQINGSK 240
Query: 226 YCGYINRLYVQYYHCTYKKRMICEKMANPVQ 256
C Y + + C+ + ICEK A PV+
Sbjct: 241 GCAYFQKGNIYISRCSAEIFWICEKTAAPVK 271
>gi|194018499 C-type lectin domain family 12, member B isoform 2
[Homo sapiens]
Length = 232
Score = 139 bits (349), Expect = 3e-33
Identities = 80/231 (34%), Positives = 130/231 (56%), Gaps = 13/231 (5%)
Query: 1 MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL 60
MSEEVTYA L FQ+S+ + ++ PAPS +WR AAL L LCL+LLIGL L
Sbjct: 1 MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTL 60
Query: 61 ASMF---HVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNIS-------NKIRNLSTTL 110
MF + + +K+++LQ ++ Q N+S QL ++ N+S ++I ++
Sbjct: 61 GMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQ 120
Query: 111 QTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSC-YFLSDDVQTWQESKMACAAQNASLL 169
+ +A KLC+EL +H+C PCP+ W W+++SC YF +++ +TW S+ C +N++L+
Sbjct: 121 EQMAIKLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLV 180
Query: 170 KINNKNALEFIKSQS--RSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRN 218
KI++ +F+ SQ +WLGLS + D + S + + N
Sbjct: 181 KIDSLEEKDFLMSQPLLMFSFFWLGLSWDSSGRSWFWEDGSVPSPSLYVSN 231
>gi|37577103 C-type lectin-like receptor-1 [Homo sapiens]
Length = 280
Score = 135 bits (341), Expect = 3e-32
Identities = 81/228 (35%), Positives = 119/228 (52%), Gaps = 9/228 (3%)
Query: 34 APSHVWRPAALFLTLLCLLLLIGLGVLASMFHVTLKIEMKKMNKLQNISEELQRNISLQL 93
APS WRP AL L LCL+LLIGL L +F ++ + + + E L N S +L
Sbjct: 42 APSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLG-NTSQEL 100
Query: 94 MSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQT 153
S + + N L+ +LQ +A KLCRELY+K H+C PC +W WH D+CY D ++
Sbjct: 101 QS-LQVQNI--KLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKS 157
Query: 154 WQESKMACAAQNASLLKINNKNALEFIKSQSRS---YDYWLGLSPEEDSTRGMRVDNIIN 210
W++ K C ++N+++LKIN + LEF SQS S Y YW GL + + +D
Sbjct: 158 WEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPF 217
Query: 211 SSA--WVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEKMANPVQ 256
+S +I + + C I + C KR +CE+ A V+
Sbjct: 218 TSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVK 265
>gi|153252029 C-type lectin domain family 1, member B isoform a
[Homo sapiens]
Length = 229
Score = 94.4 bits (233), Expect = 9e-20
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 35/225 (15%)
Query: 34 APSHVWRPAALFLTLLCLLLLIGLGVLASMFHVTLKIEMKKMNKLQNISEELQRNISLQL 93
A S WR AL L +LC+ +++GL L I +QRN
Sbjct: 25 ASSSWWRVMALILLILCVGMVVGLVALG-------------------IWSVMQRNY---- 61
Query: 94 MSNMNISNKIRNLSTTLQTIATKLCR------ELYSKEQEHKCKPCPRRWIWHKDSCYFL 147
+ + N + TLQ +A + C+ EL + HKC PC W ++ DSCY
Sbjct: 62 -----LQGENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGF 116
Query: 148 SDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLGLSPEEDSTRGMRVDN 207
TW+ESK C NA+LLKI+N+N +E+IK+++ W+GLS ++ + D
Sbjct: 117 FRHNLTWEESKQYCTDMNATLLKIDNRNIVEYIKARTHLI-RWVGLSRQKSNEVWKWEDG 175
Query: 208 IINSSAWVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEKMA 252
+ S NM C Y + + C K ++CE+ A
Sbjct: 176 SVISENMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKA 220
>gi|153252048 C-type lectin domain family 1, member B isoform b
[Homo sapiens]
Length = 196
Score = 89.0 bits (219), Expect = 4e-18
Identities = 60/194 (30%), Positives = 91/194 (46%), Gaps = 19/194 (9%)
Query: 65 HVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCR----- 119
++TL I K K IS +QRN + + N + TLQ +A + C+
Sbjct: 7 YITLNI---KTRKPALISAVMQRNY---------LQGENENRTGTLQQLAKRFCQYVVKQ 54
Query: 120 -ELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALE 178
EL + HKC PC W ++ DSCY TW+ESK C NA+LLKI+N+N +E
Sbjct: 55 SELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEESKQYCTDMNATLLKIDNRNIVE 114
Query: 179 FIKSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYY 238
+IK+++ W+GLS ++ + D + S NM C Y + +
Sbjct: 115 YIKARTHLI-RWVGLSRQKSNEVWKWEDGSVISENMFEFLEDGKGNMNCAYFHNGKMHPT 173
Query: 239 HCTYKKRMICEKMA 252
C K ++CE+ A
Sbjct: 174 FCENKHYLMCERKA 187
>gi|4505501 oxidized low density lipoprotein (lectin-like) receptor
1 [Homo sapiens]
Length = 273
Score = 88.2 bits (217), Expect = 7e-18
Identities = 71/271 (26%), Positives = 118/271 (43%), Gaps = 24/271 (8%)
Query: 5 VTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVLASMF 64
+T+ DL+ Q + GK + S W AA L +LCL L++ + VL
Sbjct: 1 MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQL 60
Query: 65 HVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSK 124
+ ++ L + ++L+ IS + + L ++T+A KL + +
Sbjct: 61 SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ 120
Query: 125 EQEH--------------KCK-PCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLL 169
+ H C PCP+ WIWH ++CY S W++S+ C + +A LL
Sbjct: 121 MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLL 180
Query: 170 KINNKNALEFIKS--QSRSYDYWLGLSPEEDSTRGMRVD-NIINSSAWVIRNAPDLNNMY 226
KIN+ L+FI+ S+ +W+GLS S + D + + + +R A ++ Y
Sbjct: 181 KINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGA--VSQTY 238
Query: 227 ----CGYINRLYVQYYHCTYKKRMICEKMAN 253
C YI R V +C IC+K AN
Sbjct: 239 PSGTCAYIQRGAVYAENCILAAFSICQKKAN 269
>gi|46409326 C-type lectin domain family 9, member A [Homo sapiens]
Length = 241
Score = 87.8 bits (216), Expect = 9e-18
Identities = 54/207 (26%), Positives = 98/207 (47%), Gaps = 8/207 (3%)
Query: 50 CLLLLIGLGVLASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTT 109
CL+++I + ++ + +K + ++ I+ + Q + Q + +N + R+ +
Sbjct: 34 CLVMVISCVFCMGLLTASIFLGVKLL-QVSTIAMQQQEKLIQQERALLNFTEWKRSCALQ 92
Query: 110 LQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLL 169
++ + L S H PCP WI +++SCY++S+ W S+ C + ++LL
Sbjct: 93 MKYCQAFMQNSLSSA---HNSSPCPNNWIQNRESCYYVSEIWSIWHTSQENCLKEGSTLL 149
Query: 170 KINNKNALEFIKSQSR----SYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNM 225
+I +K ++FI R SYDYW+GLS + S R + D S + N
Sbjct: 150 QIESKEEMDFITGSLRKIKGSYDYWVGLSQDGHSGRWLWQDGSSPSPGLLPAERSQSANQ 209
Query: 226 YCGYINRLYVQYYHCTYKKRMICEKMA 252
CGY+ + +C+ K ICEK A
Sbjct: 210 VCGYVKSNSLLSSNCSTWKYFICEKYA 236
>gi|7705338 C-type lectin domain family 4, member A isoform 1 [Homo
sapiens]
Length = 237
Score = 75.1 bits (183), Expect = 6e-14
Identities = 71/261 (27%), Positives = 111/261 (42%), Gaps = 38/261 (14%)
Query: 1 MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL 60
M+ E+TYA+++F+N + I K AP + F LLC LLI +L
Sbjct: 1 MTSEITYAEVRFKNEFKSSGINTASSAASKERTAPH---KSNTGFPKLLCASLLIFFLLL 57
Query: 61 ASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE 120
A F + I +K ++L L++ + +L+ TTL+ + + E
Sbjct: 58 AISFFIAFVIFFQKYSQL------LEKKTTKELVH------------TTLECVKKNMPVE 99
Query: 121 LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI 180
E C CP+ W +CYF+S + +WQ+S+ CA A LL IN + +FI
Sbjct: 100 ----ETAWSC--CPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFI 153
Query: 181 -KSQSRSYDYWLGLSPEEDSTRGMRVDNI---INSSAWVIRNAPDLNNMYCGYIN----- 231
++ Y++GLS E VD +S+ W R D N C +N
Sbjct: 154 FQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNER-CVVLNFRKSP 212
Query: 232 -RLYVQYYHCTYKKRMICEKM 251
R +C +R +CE M
Sbjct: 213 KRWGWNDVNCLGPQRSVCEMM 233
>gi|37675373 dendritic cell-associated C-type lectin 1 isoform a
[Homo sapiens]
Length = 247
Score = 73.2 bits (178), Expect = 2e-13
Identities = 67/254 (26%), Positives = 103/254 (40%), Gaps = 27/254 (10%)
Query: 3 EEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVLAS 62
+E Y L F + S I EK A S WR A+ L +LCL++L+ VL +
Sbjct: 11 DEDGYTQLHFDSQSNTR----IAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGT 66
Query: 63 MFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELY 122
M + + + S L+ L NK + T ++ +
Sbjct: 67 M----------AIWRSNSGSNTLENGYFLS-------RNKENHSQPTQSSLEDSVTPTKA 109
Query: 123 SKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKS 182
K PCP WI ++ SCY S + +W SK C ++LLKI++ N L FI
Sbjct: 110 VKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVK 169
Query: 183 QSRSY---DYWLGLSPEEDSTRGMRVD-NIINSSAWVIRNAPDLNN--MYCGYINRLYVQ 236
Q S +W+GLS + + D + +S+ + IR N C +I+ +
Sbjct: 170 QVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIY 229
Query: 237 YYHCTYKKRMICEK 250
C+ ICEK
Sbjct: 230 DQLCSVPSYSICEK 243
>gi|167614498 killer cell lectin-like receptor subfamily D, member 1
isoform 1 [Homo sapiens]
Length = 179
Score = 70.5 bits (171), Expect = 1e-12
Identities = 36/112 (32%), Positives = 62/112 (55%), Gaps = 4/112 (3%)
Query: 89 ISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLS 148
I L LM+ + I ++N T L +++ C C +W+ ++ +CYF+S
Sbjct: 19 ICLSLMATLGIL--LKNSFTKLSIEPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFIS 76
Query: 149 DDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLGLSPEEDST 200
+ +TW ES+ CA+Q +SLL++ N + L+F+ S + YW+GLS E+ T
Sbjct: 77 SEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQF--YWIGLSYSEEHT 126
>gi|4504889 killer cell lectin-like receptor subfamily D, member 1
isoform 1 [Homo sapiens]
Length = 179
Score = 70.5 bits (171), Expect = 1e-12
Identities = 36/112 (32%), Positives = 62/112 (55%), Gaps = 4/112 (3%)
Query: 89 ISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLS 148
I L LM+ + I ++N T L +++ C C +W+ ++ +CYF+S
Sbjct: 19 ICLSLMATLGIL--LKNSFTKLSIEPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFIS 76
Query: 149 DDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLGLSPEEDST 200
+ +TW ES+ CA+Q +SLL++ N + L+F+ S + YW+GLS E+ T
Sbjct: 77 SEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQF--YWIGLSYSEEHT 126
>gi|7669499 killer cell lectin-like receptor subfamily D, member 1
isoform 2 [Homo sapiens]
Length = 148
Score = 70.1 bits (170), Expect = 2e-12
Identities = 28/76 (36%), Positives = 50/76 (65%), Gaps = 2/76 (2%)
Query: 125 EQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQS 184
+++ C C +W+ ++ +CYF+S + +TW ES+ CA+Q +SLL++ N + L+F+ S
Sbjct: 22 QKDSDCCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQ 81
Query: 185 RSYDYWLGLSPEEDST 200
+ YW+GLS E+ T
Sbjct: 82 QF--YWIGLSYSEEHT 95
>gi|169234653 NKG2-D type II integral membrane protein [Homo
sapiens]
Length = 216
Score = 65.1 bits (157), Expect = 6e-11
Identities = 29/67 (43%), Positives = 45/67 (67%), Gaps = 2/67 (2%)
Query: 127 EHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRS 186
E C PCP+ WI +K++CY D+ + W ES+ +C +QNASLLK+ +K + +K +S
Sbjct: 93 ESYCGPCPKNWICYKNNCYQFFDESKNWYESQASCMSQNASLLKVYSKEDQDLLK-LVKS 151
Query: 187 YDYWLGL 193
Y +W+GL
Sbjct: 152 Y-HWMGL 157
>gi|37577107 C-type lectin, superfamily member 2 [Homo sapiens]
Length = 149
Score = 65.1 bits (157), Expect = 6e-11
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 14/145 (9%)
Query: 106 LSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQN 165
++T + T+ KL R+ S CP WI ++ CY+ S + W SK C+ Q+
Sbjct: 16 ITTNIITLIVKLTRDSQSL--------CPYDWIGFQNKCYYFSKEEGDWNSSKYNCSTQH 67
Query: 166 ASLLKINNKNALEFIKSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNM 225
A L I+N + F++ S D+W+GL ++ T G VD + ++ +R +
Sbjct: 68 ADLTIIDNIEEMNFLRRYKCSSDHWIGLKMAKNRT-GQWVDGATFTKSFGMRGSEG---- 122
Query: 226 YCGYINRLYVQYYHCTYKKRMICEK 250
C Y++ C +++ IC K
Sbjct: 123 -CAYLSDDGAATARCYTERKWICRK 146
>gi|7019447 osteoclast inhibitory lectin isoform 1 [Homo sapiens]
Length = 191
Score = 63.2 bits (152), Expect = 2e-10
Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 6/118 (5%)
Query: 133 CPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLG 192
CP WI + C++ SDD + W S+ C +Q+A L ++ + L F+ D+W+G
Sbjct: 75 CPESWIGFQRKCFYFSDDTKNWTSSQRFCDSQDADLAQVESFQELNFLLRYKGPSDHWIG 134
Query: 193 LSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEK 250
LS E+ IN + W R P L C Y+N +++ IC K
Sbjct: 135 LSREQGQPW-----KWINGTEWT-RQFPILGAGECAYLNDKGASSARHYTERKWICSK 186
>gi|47717094 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-A [Homo sapiens]
Length = 233
Score = 62.8 bits (151), Expect = 3e-10
Identities = 25/69 (36%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 125 EQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQS 184
++ C CP WI + +SCY++ + +TW+ES +AC ++N+SLL I+N+ ++F+ S
Sbjct: 111 QKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIIS 170
Query: 185 RSYDYWLGL 193
S W+G+
Sbjct: 171 PS--SWIGV 177
>gi|4504881 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-A [Homo sapiens]
Length = 233
Score = 62.8 bits (151), Expect = 3e-10
Identities = 25/69 (36%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 125 EQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQS 184
++ C CP WI + +SCY++ + +TW+ES +AC ++N+SLL I+N+ ++F+ S
Sbjct: 111 QKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIIS 170
Query: 185 RSYDYWLGL 193
S W+G+
Sbjct: 171 PS--SWIGV 177
>gi|75709169 killer cell lectin-like receptor subfamily C, member 2
[Homo sapiens]
Length = 231
Score = 62.4 bits (150), Expect = 4e-10
Identities = 25/69 (36%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 125 EQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQS 184
++ C CP WI + +SCY++ + +TW+ES +AC ++N+SLL I+N+ ++F+ S
Sbjct: 109 QKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLASIL 168
Query: 185 RSYDYWLGL 193
S W+G+
Sbjct: 169 PS--SWIGV 175
>gi|47717092 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-B [Homo sapiens]
Length = 215
Score = 62.4 bits (150), Expect = 4e-10
Identities = 25/64 (39%), Positives = 43/64 (67%), Gaps = 2/64 (3%)
Query: 130 CKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDY 189
C CP WI + +SCY++ + +TW+ES +AC ++N+SLL I+N+ ++F+ S S
Sbjct: 98 CGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPS--S 155
Query: 190 WLGL 193
W+G+
Sbjct: 156 WIGV 159
>gi|7262384 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-B [Homo sapiens]
Length = 215
Score = 62.4 bits (150), Expect = 4e-10
Identities = 25/64 (39%), Positives = 43/64 (67%), Gaps = 2/64 (3%)
Query: 130 CKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDY 189
C CP WI + +SCY++ + +TW+ES +AC ++N+SLL I+N+ ++F+ S S
Sbjct: 98 CGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPS--S 155
Query: 190 WLGL 193
W+G+
Sbjct: 156 WIGV 159
>gi|37675375 dendritic cell-associated C-type lectin 1 isoform c
[Homo sapiens]
Length = 189
Score = 61.6 bits (148), Expect = 7e-10
Identities = 51/185 (27%), Positives = 76/185 (41%), Gaps = 23/185 (12%)
Query: 3 EEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVLAS 62
+E Y L F + S I EK A S WR A+ L +LCL++L+ VL +
Sbjct: 11 DEDGYTQLHFDSQSNTR----IAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGT 66
Query: 63 MFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELY 122
M + + + S L+ L NK + T ++ +
Sbjct: 67 M----------AIWRSNSGSNTLENGYFLS-------RNKENHSQPTQSSLEDSVTPTKA 109
Query: 123 SKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKS 182
K PCP WI ++ SCY S + +W SK C ++LLKI++ N E I
Sbjct: 110 VKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSN--ELISD 167
Query: 183 QSRSY 187
Q+ SY
Sbjct: 168 QNHSY 172
>gi|37675379 dendritic cell-associated C-type lectin 1 isoform e
[Homo sapiens]
Length = 168
Score = 61.2 bits (147), Expect = 9e-10
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 132 PCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSY---D 188
PCP WI ++ SCY S + +W SK C ++LLKI++ N L FI Q S
Sbjct: 40 PCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNS 99
Query: 189 YWLGLSPEEDSTRGMRVD-NIINSSAWVIRNAPDLNN--MYCGYINRLYVQYYHCTYKKR 245
+W+GLS + + D + +S+ + IR N C +I+ + C+
Sbjct: 100 FWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSY 159
Query: 246 MICEK 250
ICEK
Sbjct: 160 SICEK 164
>gi|13384604 dendritic cell-associated C-type lectin 1 isoform b
[Homo sapiens]
Length = 201
Score = 61.2 bits (147), Expect = 9e-10
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 132 PCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSY---D 188
PCP WI ++ SCY S + +W SK C ++LLKI++ N L FI Q S
Sbjct: 73 PCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNS 132
Query: 189 YWLGLSPEEDSTRGMRVD-NIINSSAWVIRNAPDLNN--MYCGYINRLYVQYYHCTYKKR 245
+W+GLS + + D + +S+ + IR N C +I+ + C+
Sbjct: 133 FWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSY 192
Query: 246 MICEK 250
ICEK
Sbjct: 193 SICEK 197
Score = 32.3 bits (72), Expect = 0.44
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3 EEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVLAS 62
+E Y L F + S I EK A S WR A+ L +LCL++L+ VL +
Sbjct: 11 DEDGYTQLHFDSQSNTR----IAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGT 66
Query: 63 M 63
M
Sbjct: 67 M 67
>gi|195222725 C-type lectin domain family 2, member A [Homo sapiens]
Length = 174
Score = 60.8 bits (146), Expect = 1e-09
Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Query: 99 ISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKP--CPRRWIWHKDSCYFLSDDVQTWQE 156
I N L L I T +C + + +H KP C W+ +D C++ SDD + W
Sbjct: 23 IQNWKIGLMCFLSIIITTVCIIMIATWSKH-AKPVACSGDWLGVRDKCFYFSDDTRNWTA 81
Query: 157 SKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLGLSPEE 197
SK+ C+ Q A L +I+ + +EF+K + + +W+GLS ++
Sbjct: 82 SKIFCSLQKAELAQIDTQEDMEFLKRYAGTDMHWIGLSRKQ 122
>gi|38348296 C-type lectin domain family 4, member G [Homo sapiens]
Length = 293
Score = 58.2 bits (139), Expect = 7e-09
Identities = 28/84 (33%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 111 QTIATKLCRELYS-KEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLL 169
+ + T+L R L + + Q + C+PCP W+ + SCYF S TW ++ CA +A L+
Sbjct: 142 EDVRTELFRALEAVRLQNNSCEPCPTSWLSFEGSCYFFSVPKTTWAAAQDHCADASAHLV 201
Query: 170 KINNKNALEFIKSQSRSYDYWLGL 193
+ + F+ +R YWLGL
Sbjct: 202 IVGGLDEQGFLTRNTRGRGYWLGL 225
>gi|223278347 C-type lectin domain family 4, member M isoform 9
[Homo sapiens]
Length = 353
Score = 57.8 bits (138), Expect = 1e-08
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 15/127 (11%)
Query: 71 EMKKMNKLQNISEEL-QRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHK 129
E+ + +KLQ I +EL Q ++ + + + +I T L+T +LCR
Sbjct: 171 ELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRH--------- 221
Query: 130 CKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQ-SRSYD 188
CP+ W + + +CYF+S+ + W +S AC A L+ I F++ Q SRS
Sbjct: 222 ---CPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNR 278
Query: 189 Y-WLGLS 194
+ W+GLS
Sbjct: 279 FSWMGLS 285
>gi|223278337 C-type lectin domain family 4, member M isoform 12
[Homo sapiens]
Length = 375
Score = 57.8 bits (138), Expect = 1e-08
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 15/127 (11%)
Query: 71 EMKKMNKLQNISEEL-QRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHK 129
E+ + +KLQ I +EL Q ++ + + + +I T L+T +LCR
Sbjct: 193 ELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRH--------- 243
Query: 130 CKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQ-SRSYD 188
CP+ W + + +CYF+S+ + W +S AC A L+ I F++ Q SRS
Sbjct: 244 ---CPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNR 300
Query: 189 Y-WLGLS 194
+ W+GLS
Sbjct: 301 FSWMGLS 307
>gi|223278335 C-type lectin domain family 4, member M isoform 2
[Homo sapiens]
Length = 348
Score = 57.8 bits (138), Expect = 1e-08
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 15/127 (11%)
Query: 71 EMKKMNKLQNISEEL-QRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHK 129
E+ + +KLQ I +EL Q ++ + + + +I T L+T +LCR
Sbjct: 166 ELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRH--------- 216
Query: 130 CKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQ-SRSYD 188
CP+ W + + +CYF+S+ + W +S AC A L+ I F++ Q SRS
Sbjct: 217 ---CPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNR 273
Query: 189 Y-WLGLS 194
+ W+GLS
Sbjct: 274 FSWMGLS 280
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,859,996
Number of Sequences: 37866
Number of extensions: 395518
Number of successful extensions: 1866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1701
Number of HSP's gapped (non-prelim): 165
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.