Guide to the Human Genome
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Search of human proteins with 94538325

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
         (495 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]          1010   0.0  
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]          1010   0.0  
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]           961   0.0  
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]         410   e-114
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]         410   e-114
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]         410   e-114
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]          410   e-114
gi|238550159 estrogen-related receptor beta [Homo sapiens]            217   2e-56
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi...   217   2e-56
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi...   217   2e-56
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi...   217   2e-56
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap...   217   2e-56
gi|18860920 estrogen-related receptor alpha [Homo sapiens]            209   6e-54
gi|110611914 progesterone receptor [Homo sapiens]                     169   5e-42
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho...   162   9e-40
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof...   161   1e-39
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof...   160   2e-39
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof...   160   2e-39
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof...   160   2e-39
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof...   160   2e-39
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo...   160   2e-39
gi|58535455 androgen receptor isoform 2 [Homo sapiens]                158   1e-38
gi|21322252 androgen receptor isoform 1 [Homo sapiens]                158   1e-38
gi|66528677 nuclear receptor subfamily 3, group C, member 1 isof...   156   5e-38
gi|11415052 retinoid X receptor, beta [Homo sapiens]                  152   9e-37
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]        150   3e-36
gi|4506755 retinoid X receptor, alpha [Homo sapiens]                  146   4e-35
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom...   145   1e-34
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom...   145   1e-34
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo...   140   3e-33

>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score = 1010 bits (2612), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 1   MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
           MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
Sbjct: 1   MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60

Query: 61  NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
           NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
Sbjct: 61  NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120

Query: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
           RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
Sbjct: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180

Query: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
           NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
Sbjct: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240

Query: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
           CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
Sbjct: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300

Query: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
           LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
Sbjct: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360

Query: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
           VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
Sbjct: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420

Query: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
           DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF
Sbjct: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480

Query: 481 GMKMETLLPEATMEQ 495
           GMKMETLLPEATMEQ
Sbjct: 481 GMKMETLLPEATMEQ 495


>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score = 1010 bits (2612), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 1   MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
           MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
Sbjct: 1   MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60

Query: 61  NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
           NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
Sbjct: 61  NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120

Query: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
           RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
Sbjct: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180

Query: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
           NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
Sbjct: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240

Query: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
           CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
Sbjct: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300

Query: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
           LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
Sbjct: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360

Query: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
           VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
Sbjct: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420

Query: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
           DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF
Sbjct: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480

Query: 481 GMKMETLLPEATMEQ 495
           GMKMETLLPEATMEQ
Sbjct: 481 GMKMETLLPEATMEQ 495


>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
          Length = 530

 Score =  961 bits (2484), Expect = 0.0
 Identities = 473/489 (96%), Positives = 478/489 (97%), Gaps = 3/489 (0%)

Query: 1   MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
           MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
Sbjct: 1   MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60

Query: 61  NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
           NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
Sbjct: 61  NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120

Query: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
           RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
Sbjct: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180

Query: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
           NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
Sbjct: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240

Query: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
           CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
Sbjct: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300

Query: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
           LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
Sbjct: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360

Query: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
           VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
Sbjct: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420

Query: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
           DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHA + K  + L   
Sbjct: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHA-SNKGMEHL--L 477

Query: 481 GMKMETLLP 489
            MK + ++P
Sbjct: 478 NMKCKNVVP 486


>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
          Length = 595

 Score =  410 bits (1055), Expect = e-114
 Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)

Query: 11  NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
           N     N  Q  +PLE   G +Y+ SS   V ++ E  A  F + A  N  +    T L 
Sbjct: 21  NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79

Query: 67  GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
            GPG +                    SP +L   P  LSP L  H Q    Y E + S +
Sbjct: 80  YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139

Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
               +            +R+    R AS          S ++  +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199

Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
           WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259

Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
            G R+++ +R  D+     G+ +   G A  +R                  L  +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314

Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           +V  LL+AEPP +L S   P+ PF+EASMM  LT LAD+ELVHMI+WAK++PGFV+L+L 
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQV LLE  W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
           RFR + LQ +E++C+K++ILLNS +Y  +++T +  +    +  +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493

Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
           G++ QQQ  RLA LL++LSH+RH  + K  + L  + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535


>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
          Length = 595

 Score =  410 bits (1055), Expect = e-114
 Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)

Query: 11  NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
           N     N  Q  +PLE   G +Y+ SS   V ++ E  A  F + A  N  +    T L 
Sbjct: 21  NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79

Query: 67  GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
            GPG +                    SP +L   P  LSP L  H Q    Y E + S +
Sbjct: 80  YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139

Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
               +            +R+    R AS          S ++  +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199

Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
           WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259

Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
            G R+++ +R  D+     G+ +   G A  +R                  L  +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314

Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           +V  LL+AEPP +L S   P+ PF+EASMM  LT LAD+ELVHMI+WAK++PGFV+L+L 
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQV LLE  W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
           RFR + LQ +E++C+K++ILLNS +Y  +++T +  +    +  +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493

Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
           G++ QQQ  RLA LL++LSH+RH  + K  + L  + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535


>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
          Length = 595

 Score =  410 bits (1055), Expect = e-114
 Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)

Query: 11  NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
           N     N  Q  +PLE   G +Y+ SS   V ++ E  A  F + A  N  +    T L 
Sbjct: 21  NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79

Query: 67  GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
            GPG +                    SP +L   P  LSP L  H Q    Y E + S +
Sbjct: 80  YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139

Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
               +            +R+    R AS          S ++  +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199

Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
           WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259

Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
            G R+++ +R  D+     G+ +   G A  +R                  L  +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314

Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           +V  LL+AEPP +L S   P+ PF+EASMM  LT LAD+ELVHMI+WAK++PGFV+L+L 
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQV LLE  W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
           RFR + LQ +E++C+K++ILLNS +Y  +++T +  +    +  +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493

Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
           G++ QQQ  RLA LL++LSH+RH  + K  + L  + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535


>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
          Length = 595

 Score =  410 bits (1055), Expect = e-114
 Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)

Query: 11  NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
           N     N  Q  +PLE   G +Y+ SS   V ++ E  A  F + A  N  +    T L 
Sbjct: 21  NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79

Query: 67  GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
            GPG +                    SP +L   P  LSP L  H Q    Y E + S +
Sbjct: 80  YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139

Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
               +            +R+    R AS          S ++  +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199

Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
           WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259

Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
            G R+++ +R  D+     G+ +   G A  +R                  L  +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314

Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           +V  LL+AEPP +L S   P+ PF+EASMM  LT LAD+ELVHMI+WAK++PGFV+L+L 
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQV LLE  W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
           RFR + LQ +E++C+K++ILLNS +Y  +++T +  +    +  +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493

Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
           G++ QQQ  RLA LL++LSH+RH  + K  + L  + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535


>gi|238550159 estrogen-related receptor beta [Homo sapiens]
          Length = 508

 Score =  217 bits (553), Expect = 2e-56
 Identities = 121/287 (42%), Positives = 183/287 (63%), Gaps = 22/287 (7%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 103 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 162

Query: 209 CYEVGMVKCGSR--RERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPE 266
           C +VGM+K G R  R R G +  +R+  ++   + + +       +P  ++ L       
Sbjct: 163 CLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQI------SPPAKKPL------T 210

Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           ++V  LL AEP  +  +  P  P  +   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 211 KIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLG 270

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQ+ LL+S WME+L++G+++RS+ +  KL++A D ++D +  + + G+LE++  +L    
Sbjct: 271 DQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSR-LAGLLELYRAILQLVR 329

Query: 386 RFRELKLQHKEYLCVKAMILLNS-SMYPLVTATQDADSSRKLAHLLN 431
           R+++LK++ +E++ +KA+ L NS SMY      +D ++ +KL  LL+
Sbjct: 330 RYKKLKVEKEEFVTLKALALANSDSMY-----IEDLEAVQKLQDLLH 371


>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  217 bits (552), Expect = 2e-56
 Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
           C +VGM+K G R +R      + +R  D +            ++P +  +L+  A  P  
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212

Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           ++V  LL AEP  +  +  P+ P ++   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQ+ LL+S WME+L++G+++RS+    +L++A D ++D D+ K + G+L++ + +L    
Sbjct: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
           +++ +KL+ +E++ +KA+ L NS    +    +D ++ +KL  +L+
Sbjct: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373


>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  217 bits (552), Expect = 2e-56
 Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
           C +VGM+K G R +R      + +R  D +            ++P +  +L+  A  P  
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212

Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           ++V  LL AEP  +  +  P+ P ++   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQ+ LL+S WME+L++G+++RS+    +L++A D ++D D+ K + G+L++ + +L    
Sbjct: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
           +++ +KL+ +E++ +KA+ L NS    +    +D ++ +KL  +L+
Sbjct: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373


>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
           sapiens]
          Length = 458

 Score =  217 bits (552), Expect = 2e-56
 Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 128 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 187

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
           C +VGM+K G R +R      + +R  D +            ++P +  +L+  A  P  
Sbjct: 188 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 235

Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           ++V  LL AEP  +  +  P+ P ++   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 236 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 295

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQ+ LL+S WME+L++G+++RS+    +L++A D ++D D+ K + G+L++ + +L    
Sbjct: 296 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 354

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
           +++ +KL+ +E++ +KA+ L NS    +    +D ++ +KL  +L+
Sbjct: 355 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 396


>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  217 bits (552), Expect = 2e-56
 Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
           C +VGM+K G R +R      + +R  D +            ++P +  +L+  A  P  
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212

Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
           ++V  LL AEP  +  +  P+ P ++   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272

Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
           DQ+ LL+S WME+L++G+++RS+    +L++A D ++D D+ K + G+L++ + +L    
Sbjct: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331

Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
           +++ +KL+ +E++ +KA+ L NS    +    +D ++ +KL  +L+
Sbjct: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373


>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
          Length = 423

 Score =  209 bits (531), Expect = 6e-54
 Identities = 140/349 (40%), Positives = 195/349 (55%), Gaps = 26/349 (7%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C VC D ASGYHYGV SCE CKAFFKR+IQG  +Y CPA+N+C I K RRK+CQACR  K
Sbjct: 79  CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTK 138

Query: 209 CYEVGMVKCGSRRERC-GYRLVRRQRSADEQL-----HCAGKAKRSGGHAPRVRELLLDA 262
           C  VGM+K G R +R  G R   ++R   + L       AG    +GG  PR     ++A
Sbjct: 139 CLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGG--PRKTAAPVNA 196

Query: 263 LSPEQLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVE 321
                LV  LL  EP  +  +  P+ P      + +L  L D+E+V  ISWAK IPGF  
Sbjct: 197 -----LVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSS 251

Query: 322 LSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLL 381
           LSL DQ+ +L+S WMEVL++G+  RS+    +L FA DLVLD +EG    G+ E+   LL
Sbjct: 252 LSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EEGARAAGLGELGAALL 310

Query: 382 ATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVI 441
               R + L+L+ +EY+ +KA+ L NS    +    +DA++  +L   L+     L +  
Sbjct: 311 QLVRRLQALRLEREEYVLLKALALANSDSVHI----EDAEAVEQLREALHEA--LLEYEA 364

Query: 442 AKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF-GMKMETLLP 489
            ++G     +  R   LL+ L  +R    + A + L  F G+K+E  +P
Sbjct: 365 GRAGPGGGAERRRAGRLLLTLPLLR----QTAGKVLAHFYGVKLEGKVP 409


>gi|110611914 progesterone receptor [Homo sapiens]
          Length = 933

 Score =  169 bits (428), Expect = 5e-42
 Identities = 106/323 (32%), Positives = 167/323 (51%), Gaps = 24/323 (7%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C +C D ASG HYGV +C  CK FFKR+++G ++Y+C   N C +DK RRK+C ACRLRK
Sbjct: 567 CLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRK 626

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQ- 267
           C + GMV  G + ++     V R   A       G    S   + R         SP Q 
Sbjct: 627 CCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRF------TFSPGQD 680

Query: 268 ------LVLTLLEAEPPHVLISRPSA-PFTEASMMMSLTKLADKELVHMISWAKKIPGFV 320
                 L+  L+  EP  +     +  P T +S++ SL +L +++L+ ++ W+K +PGF 
Sbjct: 681 IQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFR 740

Query: 321 ELSLFDQVRLLESCWMEVLMMGLMWRSIDHPG--KLIFAPDLVLDRDEGKCVEGILEIFD 378
            L + DQ+ L++  WM +++ GL WRS  H     L FAPDL+L+    K       +  
Sbjct: 741 NLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMK-ESSFYSLCL 799

Query: 379 MLLATTSRFRELKLQHKEYLCVKAMILLNS-SMYPLVTATQ-DADSSRKLAHLLNAVTDA 436
            +      F +L++  +E+LC+K ++LLN+  +  L + TQ +   S  +  L+ A    
Sbjct: 800 TMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKA---- 855

Query: 437 LVWVIAKSGISSQQQSMRLANLL 459
            + +  K  +SS Q+  +L  LL
Sbjct: 856 -IGLRQKGVVSSSQRFYQLTKLL 877


>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
           sapiens]
          Length = 984

 Score =  162 bits (409), Expect = 9e-40
 Identities = 103/307 (33%), Positives = 156/307 (50%), Gaps = 24/307 (7%)

Query: 122 ETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHN 181
           E +   VS +   S  TG  S R +  C VC D ASG HYGV +C  CK FFKR+++G +
Sbjct: 578 EYIPENVSSSTLRSVSTG--SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQH 635

Query: 182 DYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHC 241
           +Y+C   N C IDK RRK+C ACRL+KC + GM   G+R+ +   +L        +Q   
Sbjct: 636 NYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGM-NLGARKSKKLGKLKGIHEEQPQQQQP 694

Query: 242 -----------AGKAKRSGGHAPRVRELLLDALSPEQLVLT-----LLEAEPPHVLIS-- 283
                       G    +    P V   L+  LS     LT     +LE   P ++ +  
Sbjct: 695 PPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGY 754

Query: 284 RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGL 343
             S P T  +++ +L +LA K+++ ++ WAK +PGF  L L DQ+ L++  WM +    L
Sbjct: 755 DSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFAL 814

Query: 344 MWRSIDHPGK--LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVK 401
            WRS  H     L FAPDLV + +E      + E+   +   + +F  L+L  +EY  +K
Sbjct: 815 SWRSYKHTNSQFLYFAPDLVFN-EEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMK 873

Query: 402 AMILLNS 408
            ++LL++
Sbjct: 874 VLLLLST 880


>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
           beta [Homo sapiens]
          Length = 742

 Score =  161 bits (408), Expect = 1e-39
 Identities = 110/351 (31%), Positives = 181/351 (51%), Gaps = 26/351 (7%)

Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
           ++  TGP  K     C VCSD ASG HYGV +C  CK FFKR+++G ++Y+C   N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465

Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
           DK RRK+C ACR RKC + GM    +R+ +   + +++  +   Q        ++     
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519

Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
            +    L  L+P   +++LLE   P VL +    S P +   +M +L  L  ++++  + 
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576

Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
           WAK IPGF  L L DQ+ LL+  WM ++   L WRS        L FAPDL+++ ++   
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635

Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
           +  + +    +L  +S    L++ ++EYLC+K ++LL+S     + + +  D  R     
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690

Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLL-MLLSHVRHARAEKASQTL 477
           +  + +    ++ + G SSQ  Q+  +L  LL  +  +V   + E  S TL
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHENVMWLKPESTSHTL 741


>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  160 bits (406), Expect = 2e-39
 Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)

Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
           ++  TGP  K     C VCSD ASG HYGV +C  CK FFKR+++G ++Y+C   N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465

Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
           DK RRK+C ACR RKC + GM    +R+ +   + +++  +   Q        ++     
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519

Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
            +    L  L+P   +++LLE   P VL +    S P +   +M +L  L  ++++  + 
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576

Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
           WAK IPGF  L L DQ+ LL+  WM ++   L WRS        L FAPDL+++ ++   
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635

Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
           +  + +    +L  +S    L++ ++EYLC+K ++LL+S     + + +  D  R     
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690

Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
           +  + +    ++ + G SSQ  Q+  +L  LL  +  V         QT     M +E  
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748

Query: 488 LPEATME 494
            PE   E
Sbjct: 749 FPEMLAE 755


>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  160 bits (406), Expect = 2e-39
 Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)

Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
           ++  TGP  K     C VCSD ASG HYGV +C  CK FFKR+++G ++Y+C   N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465

Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
           DK RRK+C ACR RKC + GM    +R+ +   + +++  +   Q        ++     
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519

Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
            +    L  L+P   +++LLE   P VL +    S P +   +M +L  L  ++++  + 
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576

Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
           WAK IPGF  L L DQ+ LL+  WM ++   L WRS        L FAPDL+++ ++   
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635

Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
           +  + +    +L  +S    L++ ++EYLC+K ++LL+S     + + +  D  R     
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690

Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
           +  + +    ++ + G SSQ  Q+  +L  LL  +  V         QT     M +E  
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748

Query: 488 LPEATME 494
            PE   E
Sbjct: 749 FPEMLAE 755


>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  160 bits (406), Expect = 2e-39
 Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)

Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
           ++  TGP  K     C VCSD ASG HYGV +C  CK FFKR+++G ++Y+C   N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465

Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
           DK RRK+C ACR RKC + GM    +R+ +   + +++  +   Q        ++     
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519

Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
            +    L  L+P   +++LLE   P VL +    S P +   +M +L  L  ++++  + 
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576

Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
           WAK IPGF  L L DQ+ LL+  WM ++   L WRS        L FAPDL+++ ++   
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635

Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
           +  + +    +L  +S    L++ ++EYLC+K ++LL+S     + + +  D  R     
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690

Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
           +  + +    ++ + G SSQ  Q+  +L  LL  +  V         QT     M +E  
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748

Query: 488 LPEATME 494
            PE   E
Sbjct: 749 FPEMLAE 755


>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  160 bits (406), Expect = 2e-39
 Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)

Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
           ++  TGP  K     C VCSD ASG HYGV +C  CK FFKR+++G ++Y+C   N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465

Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
           DK RRK+C ACR RKC + GM    +R+ +   + +++  +   Q        ++     
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519

Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
            +    L  L+P   +++LLE   P VL +    S P +   +M +L  L  ++++  + 
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576

Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
           WAK IPGF  L L DQ+ LL+  WM ++   L WRS        L FAPDL+++ ++   
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635

Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
           +  + +    +L  +S    L++ ++EYLC+K ++LL+S     + + +  D  R     
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690

Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
           +  + +    ++ + G SSQ  Q+  +L  LL  +  V         QT     M +E  
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748

Query: 488 LPEATME 494
            PE   E
Sbjct: 749 FPEMLAE 755


>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  160 bits (406), Expect = 2e-39
 Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)

Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
           ++  TGP  K     C VCSD ASG HYGV +C  CK FFKR+++G ++Y+C   N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465

Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
           DK RRK+C ACR RKC + GM    +R+ +   + +++  +   Q        ++     
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519

Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
            +    L  L+P   +++LLE   P VL +    S P +   +M +L  L  ++++  + 
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576

Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
           WAK IPGF  L L DQ+ LL+  WM ++   L WRS        L FAPDL+++ ++   
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635

Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
           +  + +    +L  +S    L++ ++EYLC+K ++LL+S     + + +  D  R     
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690

Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
           +  + +    ++ + G SSQ  Q+  +L  LL  +  V         QT     M +E  
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748

Query: 488 LPEATME 494
            PE   E
Sbjct: 749 FPEMLAE 755


>gi|58535455 androgen receptor isoform 2 [Homo sapiens]
          Length = 388

 Score =  158 bits (399), Expect = 1e-38
 Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C +C D ASG HYG  +C  CK FFKR+ +G   Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 28  CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
           CYE GM     + ++ G   ++ +  A        +  +      ++    ++    + +
Sbjct: 88  CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 141

Query: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
            L +LEA  P V+ +    + P + A+++ SL +L +++LVH++ WAK +PGF  L + D
Sbjct: 142 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 201

Query: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
           Q+ +++  WM +++  + WRS  +     L FAPDLV +       R   +CV       
Sbjct: 202 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 255

Query: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
             +   +  F  L++  +E+LC+KA++L +
Sbjct: 256 --MRHLSQEFGWLQITPQEFLCMKALLLFS 283


>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
          Length = 920

 Score =  158 bits (399), Expect = 1e-38
 Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           C +C D ASG HYG  +C  CK FFKR+ +G   Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 560 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 619

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
           CYE GM     + ++ G   ++ +  A        +  +      ++    ++    + +
Sbjct: 620 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 673

Query: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
            L +LEA  P V+ +    + P + A+++ SL +L +++LVH++ WAK +PGF  L + D
Sbjct: 674 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 733

Query: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
           Q+ +++  WM +++  + WRS  +     L FAPDLV +       R   +CV       
Sbjct: 734 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 787

Query: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
             +   +  F  L++  +E+LC+KA++L +
Sbjct: 788 --MRHLSQEFGWLQITPQEFLCMKALLLFS 815


>gi|66528677 nuclear receptor subfamily 3, group C, member 1 isoform
           gamma [Homo sapiens]
          Length = 778

 Score =  156 bits (394), Expect = 5e-38
 Identities = 113/368 (30%), Positives = 183/368 (49%), Gaps = 28/368 (7%)

Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH-NDYICPATNQCT 192
           ++  TGP  K     C VCSD ASG HYGV +C  CK FFKR+++G  ++Y+C   N C 
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRNDCI 465

Query: 193 IDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHA 252
           IDK RRK+C ACR RKC + GM    +R+ +   + +++  +   Q        ++    
Sbjct: 466 IDKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT---- 520

Query: 253 PRVRELLLDALSPEQLVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMI 310
             +    L  L+P   +++LLE   P VL +    S P +   +M +L  L  ++++  +
Sbjct: 521 --IVPATLPQLTPT--LVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAV 576

Query: 311 SWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGK 368
            WAK IPGF  L L DQ+ LL+  WM ++   L WRS        L FAPDL+++ ++  
Sbjct: 577 KWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRM 635

Query: 369 CVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAH 428
            +  + +    +L  +S    L++ ++EYLC+K ++LL+S     + + +  D  R    
Sbjct: 636 TLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR---- 691

Query: 429 LLNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMET 486
            +  + +    ++ + G SSQ  Q+  +L  LL  +  V         QT     M +E 
Sbjct: 692 -MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE- 749

Query: 487 LLPEATME 494
             PE   E
Sbjct: 750 -FPEMLAE 756


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score =  152 bits (383), Expect = 9e-37
 Identities = 100/284 (35%), Positives = 146/284 (51%), Gaps = 25/284 (8%)

Query: 128 VSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPA 187
           V G  C  P  GPG+ +    CA+C D +SG HYGV+SCEGCK FFKR+I+    Y C  
Sbjct: 186 VRGLHCPPPPGGPGAGK--RLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRD 243

Query: 188 TNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKR 247
              CT+DK +R  CQ CR +KC   GM +   + E        RQR  D+     G  + 
Sbjct: 244 NKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEE--------RQRGKDKD----GDGEG 291

Query: 248 SGGHAPRVRELLLDALSPEQLVLTLLE---AEPPHVLISRPSAPFTEASMMMSLTKLADK 304
           +GG AP   E+ +D +   +L +        E P       S+P      + ++ + ADK
Sbjct: 292 AGG-AP--EEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSP---NDPVTNICQAADK 345

Query: 305 ELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDR 364
           +L  ++ WAK+IP F  L L DQV LL + W E+L+     RSID    ++ A  L + R
Sbjct: 346 QLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHR 405

Query: 365 DEGKCVEGILEIFDMLLA-TTSRFRELKLQHKEYLCVKAMILLN 407
           +      G+  IFD +L    S+ R++++   E  C++A+IL N
Sbjct: 406 NSAHSA-GVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFN 448


>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
          Length = 463

 Score =  150 bits (379), Expect = 3e-36
 Identities = 104/332 (31%), Positives = 156/332 (46%), Gaps = 32/332 (9%)

Query: 136 PVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDK 195
           P T PGS    H CA+C D +SG HYGV+SCEGCK FFKR+I+    Y C     C IDK
Sbjct: 127 PSTSPGSLVK-HICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDK 185

Query: 196 NRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRV 255
            +R  CQ CR +KC  +GM +   + ER      R +  A+ +  CA     + GH    
Sbjct: 186 RQRNRCQYCRYQKCLVMGMKREAVQEER-----QRSRERAESEAECA-----TSGHEDMP 235

Query: 256 RELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKK 315
            E +L+A          L  EP        +   +    + ++   ADK+L  ++ WAK+
Sbjct: 236 VERILEA---------ELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKR 286

Query: 316 IPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILE 375
           IP F +L+L DQV LL + W E+L+     RS+     ++ A  L + R       G+  
Sbjct: 287 IPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSA-GVGS 345

Query: 376 IFDMLLA-TTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVT 434
           IFD +L    S+ +++++   E  C++A++L N     L   ++      K+   L A T
Sbjct: 346 IFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYT 405

Query: 435 DALVWVIAKSGISSQQQSMRLANLLMLLSHVR 466
                          +Q  R A LL+ L  +R
Sbjct: 406 KQ----------KYPEQPGRFAKLLLRLPALR 427


>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
          Length = 462

 Score =  146 bits (369), Expect = 4e-35
 Identities = 91/262 (34%), Positives = 135/262 (51%), Gaps = 18/262 (6%)

Query: 147 HFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRL 206
           H CA+C D +SG HYGV+SCEGCK FFKR+++    Y C     C IDK +R  CQ CR 
Sbjct: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRY 192

Query: 207 RKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPE 266
           +KC  +GM +   + E        RQR  D   +       +    P V  +L   L+ E
Sbjct: 193 QKCLAMGMKREAVQEE--------RQRGKDRNENEVESTSSANEDMP-VERILEAELAVE 243

Query: 267 QLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
               T +EA     +   PS+P      + ++ + ADK+L  ++ WAK+IP F EL L D
Sbjct: 244 PKTETYVEAN----MGLNPSSP---NDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDD 296

Query: 327 QVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLA-TTS 385
           QV LL + W E+L+     RSI     ++ A  L + R+      G+  IFD +L    S
Sbjct: 297 QVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVS 355

Query: 386 RFRELKLQHKEYLCVKAMILLN 407
           + R++++   E  C++A++L N
Sbjct: 356 KMRDMQMDKTELGCLRAIVLFN 377


>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score =  145 bits (365), Expect = 1e-34
 Identities = 117/357 (32%), Positives = 158/357 (44%), Gaps = 56/357 (15%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           CAVC D AS  HYGV +CEGCK FFKR++Q +  YIC A   C +DK RR  CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
           C  VGMVK           +VR               K   G  P   +   DA SP  L
Sbjct: 327 CLAVGMVK----------EVVRTD-----------SLKGRRGRLPSKPKQPPDA-SPANL 364

Query: 269 VLTLLEAEPPHVLISRPSAPFTEASMMMSLT----------------KLADKELVHMISW 312
           + +L+ A     L S PS    + S    L                  L    L  +  W
Sbjct: 365 LTSLVRAH----LDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420

Query: 313 AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEG 372
           A+KIPGF ELS  DQ  LLES ++E+ ++ L +RS    GKLIF   LVL R +  C  G
Sbjct: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--CARG 478

Query: 373 ILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNA 432
             +  D +LA +     L +    + C+ A++        L+T        R++  L N 
Sbjct: 479 FGDWIDSILAFSRSLHSLLVDVPAFACLSALV--------LITDRHGLQEPRRVEELQNR 530

Query: 433 VTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
           +   L   +A      Q  S  L+ LL  L  +R    +   +    F +K+E L+P
Sbjct: 531 IASCLKEHVAAVAGEPQPASC-LSRLLGKLPELRTLCTQGLQRI---FYLKLEDLVP 583


>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score =  145 bits (365), Expect = 1e-34
 Identities = 117/357 (32%), Positives = 158/357 (44%), Gaps = 56/357 (15%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
           CAVC D AS  HYGV +CEGCK FFKR++Q +  YIC A   C +DK RR  CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326

Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
           C  VGMVK           +VR               K   G  P   +   DA SP  L
Sbjct: 327 CLAVGMVK----------EVVRTD-----------SLKGRRGRLPSKPKQPPDA-SPANL 364

Query: 269 VLTLLEAEPPHVLISRPSAPFTEASMMMSLT----------------KLADKELVHMISW 312
           + +L+ A     L S PS    + S    L                  L    L  +  W
Sbjct: 365 LTSLVRAH----LDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420

Query: 313 AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEG 372
           A+KIPGF ELS  DQ  LLES ++E+ ++ L +RS    GKLIF   LVL R +  C  G
Sbjct: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--CARG 478

Query: 373 ILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNA 432
             +  D +LA +     L +    + C+ A++        L+T        R++  L N 
Sbjct: 479 FGDWIDSILAFSRSLHSLLVDVPAFACLSALV--------LITDRHGLQEPRRVEELQNR 530

Query: 433 VTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
           +   L   +A      Q  S  L+ LL  L  +R    +   +    F +K+E L+P
Sbjct: 531 IASCLKEHVAAVAGEPQPASC-LSRLLGKLPELRTLCTQGLQRI---FYLKLEDLVP 583


>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
           sapiens]
          Length = 385

 Score =  140 bits (353), Expect = 3e-33
 Identities = 105/350 (30%), Positives = 161/350 (46%), Gaps = 46/350 (13%)

Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQ--CTIDKNRRKSCQACRL 206
           C VC D +SG HYGV++C+GC  FFKRSI+ +  Y+C + NQ  C +DK  R  C+ACRL
Sbjct: 16  CKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRL 75

Query: 207 RKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHA-------------- 252
           +KC EV M K   + ER       R++ A   L+  G  + +G  A              
Sbjct: 76  KKCLEVNMNKDAVQHERGPRTSTIRKQVA---LYFRGHKEENGAAAHFPSAALPAPAFFT 132

Query: 253 ------PRVRELLLDALSPE-QLVLTLLEAEP--PHVLISRPSAPFTEASMMMSLTKLAD 303
                 P   EL   + +PE Q +++L +  P  PH +   P   +  A+   S+ + A 
Sbjct: 133 AVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVAT--ESVCESAA 190

Query: 304 KELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGL-MWRSIDHPGKLIFAPDLVL 362
           + L   I WAK +P F  LSL DQ+ LLE  W E+ ++G+  W        L+    +  
Sbjct: 191 RLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNG 250

Query: 363 DRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADS 422
           D  + + +  I+     L    +RFR+L+L   E+ C+K ++   +             S
Sbjct: 251 DNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKA---------VPTHS 301

Query: 423 SRKLAHLLNAVTDALVWVIAKSGISS------QQQSMRLANLLMLLSHVR 466
             +L    NA   A +   A+  ++S        Q  R   LL+LL  +R
Sbjct: 302 GSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALR 351


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.132    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,259,879
Number of Sequences: 37866
Number of extensions: 962674
Number of successful extensions: 2494
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 2197
Number of HSP's gapped (non-prelim): 217
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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