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Search of human proteins with 94538325
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
(495 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens] 1010 0.0
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens] 1010 0.0
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens] 961 0.0
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 410 e-114
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 410 e-114
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 410 e-114
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 410 e-114
gi|238550159 estrogen-related receptor beta [Homo sapiens] 217 2e-56
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 217 2e-56
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 217 2e-56
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 217 2e-56
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 217 2e-56
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 209 6e-54
gi|110611914 progesterone receptor [Homo sapiens] 169 5e-42
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho... 162 9e-40
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof... 161 1e-39
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof... 160 2e-39
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof... 160 2e-39
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof... 160 2e-39
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof... 160 2e-39
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo... 160 2e-39
gi|58535455 androgen receptor isoform 2 [Homo sapiens] 158 1e-38
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 158 1e-38
gi|66528677 nuclear receptor subfamily 3, group C, member 1 isof... 156 5e-38
gi|11415052 retinoid X receptor, beta [Homo sapiens] 152 9e-37
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 150 3e-36
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 146 4e-35
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 145 1e-34
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 145 1e-34
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo... 140 3e-33
>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 1010 bits (2612), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
Sbjct: 1 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
Query: 61 NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
Sbjct: 61 NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
Query: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
Sbjct: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
Query: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
Sbjct: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
Query: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
Sbjct: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
Query: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
Sbjct: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
Query: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
Sbjct: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
Query: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF
Sbjct: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
Query: 481 GMKMETLLPEATMEQ 495
GMKMETLLPEATMEQ
Sbjct: 481 GMKMETLLPEATMEQ 495
>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 1010 bits (2612), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
Sbjct: 1 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
Query: 61 NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
Sbjct: 61 NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
Query: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
Sbjct: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
Query: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
Sbjct: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
Query: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
Sbjct: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
Query: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
Sbjct: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
Query: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
Sbjct: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
Query: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF
Sbjct: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
Query: 481 GMKMETLLPEATMEQ 495
GMKMETLLPEATMEQ
Sbjct: 481 GMKMETLLPEATMEQ 495
>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
Length = 530
Score = 961 bits (2484), Expect = 0.0
Identities = 473/489 (96%), Positives = 478/489 (97%), Gaps = 3/489 (0%)
Query: 1 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
Sbjct: 1 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS 60
Query: 61 NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
Sbjct: 61 NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN 120
Query: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
Sbjct: 121 RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH 180
Query: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
Sbjct: 181 NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH 240
Query: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
Sbjct: 241 CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK 300
Query: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
Sbjct: 301 LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL 360
Query: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
Sbjct: 361 VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA 420
Query: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF 480
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHA + K + L
Sbjct: 421 DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHA-SNKGMEHL--L 477
Query: 481 GMKMETLLP 489
MK + ++P
Sbjct: 478 NMKCKNVVP 486
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 410 bits (1055), Expect = e-114
Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)
Query: 11 NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
N N Q +PLE G +Y+ SS V ++ E A F + A N + T L
Sbjct: 21 NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
Query: 67 GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
GPG + SP +L P LSP L H Q Y E + S +
Sbjct: 80 YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
+ +R+ R AS S ++ +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
G R+++ +R D+ G+ + G A +R L +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
+V LL+AEPP +L S P+ PF+EASMM LT LAD+ELVHMI+WAK++PGFV+L+L
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQV LLE W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
RFR + LQ +E++C+K++ILLNS +Y +++T + + + +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
G++ QQQ RLA LL++LSH+RH + K + L + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 410 bits (1055), Expect = e-114
Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)
Query: 11 NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
N N Q +PLE G +Y+ SS V ++ E A F + A N + T L
Sbjct: 21 NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
Query: 67 GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
GPG + SP +L P LSP L H Q Y E + S +
Sbjct: 80 YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
+ +R+ R AS S ++ +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
G R+++ +R D+ G+ + G A +R L +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
+V LL+AEPP +L S P+ PF+EASMM LT LAD+ELVHMI+WAK++PGFV+L+L
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQV LLE W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
RFR + LQ +E++C+K++ILLNS +Y +++T + + + +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
G++ QQQ RLA LL++LSH+RH + K + L + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 410 bits (1055), Expect = e-114
Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)
Query: 11 NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
N N Q +PLE G +Y+ SS V ++ E A F + A N + T L
Sbjct: 21 NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
Query: 67 GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
GPG + SP +L P LSP L H Q Y E + S +
Sbjct: 80 YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
+ +R+ R AS S ++ +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
G R+++ +R D+ G+ + G A +R L +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
+V LL+AEPP +L S P+ PF+EASMM LT LAD+ELVHMI+WAK++PGFV+L+L
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQV LLE W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
RFR + LQ +E++C+K++ILLNS +Y +++T + + + +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
G++ QQQ RLA LL++LSH+RH + K + L + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 410 bits (1055), Expect = e-114
Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)
Query: 11 NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
N N Q +PLE G +Y+ SS V ++ E A F + A N + T L
Sbjct: 21 NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
Query: 67 GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
GPG + SP +L P LSP L H Q Y E + S +
Sbjct: 80 YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
Query: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
+ +R+ R AS S ++ +CAVC+DYASGYHYGV
Sbjct: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
Query: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
Query: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
G R+++ +R D+ G+ + G A +R L +L+ +Q
Sbjct: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
Query: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
+V LL+AEPP +L S P+ PF+EASMM LT LAD+ELVHMI+WAK++PGFV+L+L
Sbjct: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQV LLE W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
RFR + LQ +E++C+K++ILLNS +Y +++T + + + +L+ +TD L+ ++AK+
Sbjct: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
Query: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
G++ QQQ RLA LL++LSH+RH + K + L + MK + ++P
Sbjct: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 217 bits (553), Expect = 2e-56
Identities = 121/287 (42%), Positives = 183/287 (63%), Gaps = 22/287 (7%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 103 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 162
Query: 209 CYEVGMVKCGSR--RERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPE 266
C +VGM+K G R R R G + +R+ ++ + + + +P ++ L
Sbjct: 163 CLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQI------SPPAKKPL------T 210
Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
++V LL AEP + + P P + + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 211 KIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLG 270
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQ+ LL+S WME+L++G+++RS+ + KL++A D ++D + + + G+LE++ +L
Sbjct: 271 DQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSR-LAGLLELYRAILQLVR 329
Query: 386 RFRELKLQHKEYLCVKAMILLNS-SMYPLVTATQDADSSRKLAHLLN 431
R+++LK++ +E++ +KA+ L NS SMY +D ++ +KL LL+
Sbjct: 330 RYKKLKVEKEEFVTLKALALANSDSMY-----IEDLEAVQKLQDLLH 371
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 217 bits (552), Expect = 2e-56
Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
C +VGM+K G R +R + +R D + ++P + +L+ A P
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
++V LL AEP + + P+ P ++ + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQ+ LL+S WME+L++G+++RS+ +L++A D ++D D+ K + G+L++ + +L
Sbjct: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
+++ +KL+ +E++ +KA+ L NS + +D ++ +KL +L+
Sbjct: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 217 bits (552), Expect = 2e-56
Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
C +VGM+K G R +R + +R D + ++P + +L+ A P
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
++V LL AEP + + P+ P ++ + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQ+ LL+S WME+L++G+++RS+ +L++A D ++D D+ K + G+L++ + +L
Sbjct: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
+++ +KL+ +E++ +KA+ L NS + +D ++ +KL +L+
Sbjct: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 217 bits (552), Expect = 2e-56
Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 128 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 187
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
C +VGM+K G R +R + +R D + ++P + +L+ A P
Sbjct: 188 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 235
Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
++V LL AEP + + P+ P ++ + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 236 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 295
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQ+ LL+S WME+L++G+++RS+ +L++A D ++D D+ K + G+L++ + +L
Sbjct: 296 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 354
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
+++ +KL+ +E++ +KA+ L NS + +D ++ +KL +L+
Sbjct: 355 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 396
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 217 bits (552), Expect = 2e-56
Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
C +VGM+K G R +R + +R D + ++P + +L+ A P
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
Query: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
++V LL AEP + + P+ P ++ + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
Query: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
DQ+ LL+S WME+L++G+++RS+ +L++A D ++D D+ K + G+L++ + +L
Sbjct: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
Query: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
+++ +KL+ +E++ +KA+ L NS + +D ++ +KL +L+
Sbjct: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 209 bits (531), Expect = 6e-54
Identities = 140/349 (40%), Positives = 195/349 (55%), Gaps = 26/349 (7%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK+CQACR K
Sbjct: 79 CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTK 138
Query: 209 CYEVGMVKCGSRRERC-GYRLVRRQRSADEQL-----HCAGKAKRSGGHAPRVRELLLDA 262
C VGM+K G R +R G R ++R + L AG +GG PR ++A
Sbjct: 139 CLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGG--PRKTAAPVNA 196
Query: 263 LSPEQLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVE 321
LV LL EP + + P+ P + +L L D+E+V ISWAK IPGF
Sbjct: 197 -----LVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSS 251
Query: 322 LSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLL 381
LSL DQ+ +L+S WMEVL++G+ RS+ +L FA DLVLD +EG G+ E+ LL
Sbjct: 252 LSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EEGARAAGLGELGAALL 310
Query: 382 ATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVI 441
R + L+L+ +EY+ +KA+ L NS + +DA++ +L L+ L +
Sbjct: 311 QLVRRLQALRLEREEYVLLKALALANSDSVHI----EDAEAVEQLREALHEA--LLEYEA 364
Query: 442 AKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF-GMKMETLLP 489
++G + R LL+ L +R + A + L F G+K+E +P
Sbjct: 365 GRAGPGGGAERRRAGRLLLTLPLLR----QTAGKVLAHFYGVKLEGKVP 409
>gi|110611914 progesterone receptor [Homo sapiens]
Length = 933
Score = 169 bits (428), Expect = 5e-42
Identities = 106/323 (32%), Positives = 167/323 (51%), Gaps = 24/323 (7%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C +C D ASG HYGV +C CK FFKR+++G ++Y+C N C +DK RRK+C ACRLRK
Sbjct: 567 CLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRK 626
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQ- 267
C + GMV G + ++ V R A G S + R SP Q
Sbjct: 627 CCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRF------TFSPGQD 680
Query: 268 ------LVLTLLEAEPPHVLISRPSA-PFTEASMMMSLTKLADKELVHMISWAKKIPGFV 320
L+ L+ EP + + P T +S++ SL +L +++L+ ++ W+K +PGF
Sbjct: 681 IQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFR 740
Query: 321 ELSLFDQVRLLESCWMEVLMMGLMWRSIDHPG--KLIFAPDLVLDRDEGKCVEGILEIFD 378
L + DQ+ L++ WM +++ GL WRS H L FAPDL+L+ K +
Sbjct: 741 NLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMK-ESSFYSLCL 799
Query: 379 MLLATTSRFRELKLQHKEYLCVKAMILLNS-SMYPLVTATQ-DADSSRKLAHLLNAVTDA 436
+ F +L++ +E+LC+K ++LLN+ + L + TQ + S + L+ A
Sbjct: 800 TMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKA---- 855
Query: 437 LVWVIAKSGISSQQQSMRLANLL 459
+ + K +SS Q+ +L LL
Sbjct: 856 -IGLRQKGVVSSSQRFYQLTKLL 877
>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
sapiens]
Length = 984
Score = 162 bits (409), Expect = 9e-40
Identities = 103/307 (33%), Positives = 156/307 (50%), Gaps = 24/307 (7%)
Query: 122 ETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHN 181
E + VS + S TG S R + C VC D ASG HYGV +C CK FFKR+++G +
Sbjct: 578 EYIPENVSSSTLRSVSTG--SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQH 635
Query: 182 DYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHC 241
+Y+C N C IDK RRK+C ACRL+KC + GM G+R+ + +L +Q
Sbjct: 636 NYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGM-NLGARKSKKLGKLKGIHEEQPQQQQP 694
Query: 242 -----------AGKAKRSGGHAPRVRELLLDALSPEQLVLT-----LLEAEPPHVLIS-- 283
G + P V L+ LS LT +LE P ++ +
Sbjct: 695 PPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGY 754
Query: 284 RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGL 343
S P T +++ +L +LA K+++ ++ WAK +PGF L L DQ+ L++ WM + L
Sbjct: 755 DSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFAL 814
Query: 344 MWRSIDHPGK--LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVK 401
WRS H L FAPDLV + +E + E+ + + +F L+L +EY +K
Sbjct: 815 SWRSYKHTNSQFLYFAPDLVFN-EEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMK 873
Query: 402 AMILLNS 408
++LL++
Sbjct: 874 VLLLLST 880
>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
beta [Homo sapiens]
Length = 742
Score = 161 bits (408), Expect = 1e-39
Identities = 110/351 (31%), Positives = 181/351 (51%), Gaps = 26/351 (7%)
Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
++ TGP K C VCSD ASG HYGV +C CK FFKR+++G ++Y+C N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465
Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
DK RRK+C ACR RKC + GM +R+ + + +++ + Q ++
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519
Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
+ L L+P +++LLE P VL + S P + +M +L L ++++ +
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576
Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
WAK IPGF L L DQ+ LL+ WM ++ L WRS L FAPDL+++ ++
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635
Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
+ + + +L +S L++ ++EYLC+K ++LL+S + + + D R
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690
Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLL-MLLSHVRHARAEKASQTL 477
+ + + ++ + G SSQ Q+ +L LL + +V + E S TL
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHENVMWLKPESTSHTL 741
>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 160 bits (406), Expect = 2e-39
Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)
Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
++ TGP K C VCSD ASG HYGV +C CK FFKR+++G ++Y+C N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465
Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
DK RRK+C ACR RKC + GM +R+ + + +++ + Q ++
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519
Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
+ L L+P +++LLE P VL + S P + +M +L L ++++ +
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576
Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
WAK IPGF L L DQ+ LL+ WM ++ L WRS L FAPDL+++ ++
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635
Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
+ + + +L +S L++ ++EYLC+K ++LL+S + + + D R
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690
Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
+ + + ++ + G SSQ Q+ +L LL + V QT M +E
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748
Query: 488 LPEATME 494
PE E
Sbjct: 749 FPEMLAE 755
>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 160 bits (406), Expect = 2e-39
Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)
Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
++ TGP K C VCSD ASG HYGV +C CK FFKR+++G ++Y+C N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465
Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
DK RRK+C ACR RKC + GM +R+ + + +++ + Q ++
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519
Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
+ L L+P +++LLE P VL + S P + +M +L L ++++ +
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576
Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
WAK IPGF L L DQ+ LL+ WM ++ L WRS L FAPDL+++ ++
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635
Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
+ + + +L +S L++ ++EYLC+K ++LL+S + + + D R
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690
Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
+ + + ++ + G SSQ Q+ +L LL + V QT M +E
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748
Query: 488 LPEATME 494
PE E
Sbjct: 749 FPEMLAE 755
>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 160 bits (406), Expect = 2e-39
Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)
Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
++ TGP K C VCSD ASG HYGV +C CK FFKR+++G ++Y+C N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465
Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
DK RRK+C ACR RKC + GM +R+ + + +++ + Q ++
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519
Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
+ L L+P +++LLE P VL + S P + +M +L L ++++ +
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576
Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
WAK IPGF L L DQ+ LL+ WM ++ L WRS L FAPDL+++ ++
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635
Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
+ + + +L +S L++ ++EYLC+K ++LL+S + + + D R
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690
Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
+ + + ++ + G SSQ Q+ +L LL + V QT M +E
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748
Query: 488 LPEATME 494
PE E
Sbjct: 749 FPEMLAE 755
>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 160 bits (406), Expect = 2e-39
Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)
Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
++ TGP K C VCSD ASG HYGV +C CK FFKR+++G ++Y+C N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465
Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
DK RRK+C ACR RKC + GM +R+ + + +++ + Q ++
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519
Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
+ L L+P +++LLE P VL + S P + +M +L L ++++ +
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576
Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
WAK IPGF L L DQ+ LL+ WM ++ L WRS L FAPDL+++ ++
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635
Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
+ + + +L +S L++ ++EYLC+K ++LL+S + + + D R
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690
Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
+ + + ++ + G SSQ Q+ +L LL + V QT M +E
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748
Query: 488 LPEATME 494
PE E
Sbjct: 749 FPEMLAE 755
>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 160 bits (406), Expect = 2e-39
Identities = 113/367 (30%), Positives = 183/367 (49%), Gaps = 27/367 (7%)
Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTI 193
++ TGP K C VCSD ASG HYGV +C CK FFKR+++G ++Y+C N C I
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCII 465
Query: 194 DKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAP 253
DK RRK+C ACR RKC + GM +R+ + + +++ + Q ++
Sbjct: 466 DKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT----- 519
Query: 254 RVRELLLDALSPEQLVLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMIS 311
+ L L+P +++LLE P VL + S P + +M +L L ++++ +
Sbjct: 520 -IVPATLPQLTP--TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVK 576
Query: 312 WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGKC 369
WAK IPGF L L DQ+ LL+ WM ++ L WRS L FAPDL+++ ++
Sbjct: 577 WAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRMT 635
Query: 370 VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHL 429
+ + + +L +S L++ ++EYLC+K ++LL+S + + + D R
Sbjct: 636 LPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR----- 690
Query: 430 LNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETL 487
+ + + ++ + G SSQ Q+ +L LL + V QT M +E
Sbjct: 691 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE-- 748
Query: 488 LPEATME 494
PE E
Sbjct: 749 FPEMLAE 755
>gi|58535455 androgen receptor isoform 2 [Homo sapiens]
Length = 388
Score = 158 bits (399), Expect = 1e-38
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 141
Query: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 142 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 201
Query: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 202 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 255
Query: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
+ + F L++ +E+LC+KA++L +
Sbjct: 256 --MRHLSQEFGWLQITPQEFLCMKALLLFS 283
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 158 bits (399), Expect = 1e-38
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 560 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 619
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 620 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 673
Query: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 674 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 733
Query: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 734 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 787
Query: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
+ + F L++ +E+LC+KA++L +
Sbjct: 788 --MRHLSQEFGWLQITPQEFLCMKALLLFS 815
>gi|66528677 nuclear receptor subfamily 3, group C, member 1 isoform
gamma [Homo sapiens]
Length = 778
Score = 156 bits (394), Expect = 5e-38
Identities = 113/368 (30%), Positives = 183/368 (49%), Gaps = 28/368 (7%)
Query: 134 ASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH-NDYICPATNQCT 192
++ TGP K C VCSD ASG HYGV +C CK FFKR+++G ++Y+C N C
Sbjct: 410 STATTGPPPK----LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRNDCI 465
Query: 193 IDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHA 252
IDK RRK+C ACR RKC + GM +R+ + + +++ + Q ++
Sbjct: 466 IDKIRRKNCPACRYRKCLQAGM-NLEARKTKKKIKGIQQATTGVSQETSENPGNKT---- 520
Query: 253 PRVRELLLDALSPEQLVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMI 310
+ L L+P +++LLE P VL + S P + +M +L L ++++ +
Sbjct: 521 --IVPATLPQLTPT--LVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAV 576
Query: 311 SWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSI--DHPGKLIFAPDLVLDRDEGK 368
WAK IPGF L L DQ+ LL+ WM ++ L WRS L FAPDL+++ ++
Sbjct: 577 KWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIIN-EQRM 635
Query: 369 CVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAH 428
+ + + +L +S L++ ++EYLC+K ++LL+S + + + D R
Sbjct: 636 TLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIR---- 691
Query: 429 LLNAVTDALVWVIAKSGISSQ--QQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMET 486
+ + + ++ + G SSQ Q+ +L LL + V QT M +E
Sbjct: 692 -MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIE- 749
Query: 487 LLPEATME 494
PE E
Sbjct: 750 -FPEMLAE 756
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 152 bits (383), Expect = 9e-37
Identities = 100/284 (35%), Positives = 146/284 (51%), Gaps = 25/284 (8%)
Query: 128 VSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPA 187
V G C P GPG+ + CA+C D +SG HYGV+SCEGCK FFKR+I+ Y C
Sbjct: 186 VRGLHCPPPPGGPGAGK--RLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRD 243
Query: 188 TNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKR 247
CT+DK +R CQ CR +KC GM + + E RQR D+ G +
Sbjct: 244 NKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEE--------RQRGKDKD----GDGEG 291
Query: 248 SGGHAPRVRELLLDALSPEQLVLTLLE---AEPPHVLISRPSAPFTEASMMMSLTKLADK 304
+GG AP E+ +D + +L + E P S+P + ++ + ADK
Sbjct: 292 AGG-AP--EEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSP---NDPVTNICQAADK 345
Query: 305 ELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDR 364
+L ++ WAK+IP F L L DQV LL + W E+L+ RSID ++ A L + R
Sbjct: 346 QLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHR 405
Query: 365 DEGKCVEGILEIFDMLLA-TTSRFRELKLQHKEYLCVKAMILLN 407
+ G+ IFD +L S+ R++++ E C++A+IL N
Sbjct: 406 NSAHSA-GVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFN 448
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 150 bits (379), Expect = 3e-36
Identities = 104/332 (31%), Positives = 156/332 (46%), Gaps = 32/332 (9%)
Query: 136 PVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDK 195
P T PGS H CA+C D +SG HYGV+SCEGCK FFKR+I+ Y C C IDK
Sbjct: 127 PSTSPGSLVK-HICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDK 185
Query: 196 NRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRV 255
+R CQ CR +KC +GM + + ER R + A+ + CA + GH
Sbjct: 186 RQRNRCQYCRYQKCLVMGMKREAVQEER-----QRSRERAESEAECA-----TSGHEDMP 235
Query: 256 RELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKK 315
E +L+A L EP + + + ++ ADK+L ++ WAK+
Sbjct: 236 VERILEA---------ELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKR 286
Query: 316 IPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILE 375
IP F +L+L DQV LL + W E+L+ RS+ ++ A L + R G+
Sbjct: 287 IPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSA-GVGS 345
Query: 376 IFDMLLA-TTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVT 434
IFD +L S+ +++++ E C++A++L N L ++ K+ L A T
Sbjct: 346 IFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYT 405
Query: 435 DALVWVIAKSGISSQQQSMRLANLLMLLSHVR 466
+Q R A LL+ L +R
Sbjct: 406 KQ----------KYPEQPGRFAKLLLRLPALR 427
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 146 bits (369), Expect = 4e-35
Identities = 91/262 (34%), Positives = 135/262 (51%), Gaps = 18/262 (6%)
Query: 147 HFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRL 206
H CA+C D +SG HYGV+SCEGCK FFKR+++ Y C C IDK +R CQ CR
Sbjct: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRY 192
Query: 207 RKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPE 266
+KC +GM + + E RQR D + + P V +L L+ E
Sbjct: 193 QKCLAMGMKREAVQEE--------RQRGKDRNENEVESTSSANEDMP-VERILEAELAVE 243
Query: 267 QLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
T +EA + PS+P + ++ + ADK+L ++ WAK+IP F EL L D
Sbjct: 244 PKTETYVEAN----MGLNPSSP---NDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDD 296
Query: 327 QVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLA-TTS 385
QV LL + W E+L+ RSI ++ A L + R+ G+ IFD +L S
Sbjct: 297 QVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVS 355
Query: 386 RFRELKLQHKEYLCVKAMILLN 407
+ R++++ E C++A++L N
Sbjct: 356 KMRDMQMDKTELGCLRAIVLFN 377
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 145 bits (365), Expect = 1e-34
Identities = 117/357 (32%), Positives = 158/357 (44%), Gaps = 56/357 (15%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
CAVC D AS HYGV +CEGCK FFKR++Q + YIC A C +DK RR CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
C VGMVK +VR K G P + DA SP L
Sbjct: 327 CLAVGMVK----------EVVRTD-----------SLKGRRGRLPSKPKQPPDA-SPANL 364
Query: 269 VLTLLEAEPPHVLISRPSAPFTEASMMMSLT----------------KLADKELVHMISW 312
+ +L+ A L S PS + S L L L + W
Sbjct: 365 LTSLVRAH----LDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420
Query: 313 AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEG 372
A+KIPGF ELS DQ LLES ++E+ ++ L +RS GKLIF LVL R + C G
Sbjct: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--CARG 478
Query: 373 ILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNA 432
+ D +LA + L + + C+ A++ L+T R++ L N
Sbjct: 479 FGDWIDSILAFSRSLHSLLVDVPAFACLSALV--------LITDRHGLQEPRRVEELQNR 530
Query: 433 VTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
+ L +A Q S L+ LL L +R + + F +K+E L+P
Sbjct: 531 IASCLKEHVAAVAGEPQPASC-LSRLLGKLPELRTLCTQGLQRI---FYLKLEDLVP 583
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 145 bits (365), Expect = 1e-34
Identities = 117/357 (32%), Positives = 158/357 (44%), Gaps = 56/357 (15%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
CAVC D AS HYGV +CEGCK FFKR++Q + YIC A C +DK RR CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
C VGMVK +VR K G P + DA SP L
Sbjct: 327 CLAVGMVK----------EVVRTD-----------SLKGRRGRLPSKPKQPPDA-SPANL 364
Query: 269 VLTLLEAEPPHVLISRPSAPFTEASMMMSLT----------------KLADKELVHMISW 312
+ +L+ A L S PS + S L L L + W
Sbjct: 365 LTSLVRAH----LDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420
Query: 313 AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEG 372
A+KIPGF ELS DQ LLES ++E+ ++ L +RS GKLIF LVL R + C G
Sbjct: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--CARG 478
Query: 373 ILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNA 432
+ D +LA + L + + C+ A++ L+T R++ L N
Sbjct: 479 FGDWIDSILAFSRSLHSLLVDVPAFACLSALV--------LITDRHGLQEPRRVEELQNR 530
Query: 433 VTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
+ L +A Q S L+ LL L +R + + F +K+E L+P
Sbjct: 531 IASCLKEHVAAVAGEPQPASC-LSRLLGKLPELRTLCTQGLQRI---FYLKLEDLVP 583
>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
sapiens]
Length = 385
Score = 140 bits (353), Expect = 3e-33
Identities = 105/350 (30%), Positives = 161/350 (46%), Gaps = 46/350 (13%)
Query: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQ--CTIDKNRRKSCQACRL 206
C VC D +SG HYGV++C+GC FFKRSI+ + Y+C + NQ C +DK R C+ACRL
Sbjct: 16 CKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRL 75
Query: 207 RKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHA-------------- 252
+KC EV M K + ER R++ A L+ G + +G A
Sbjct: 76 KKCLEVNMNKDAVQHERGPRTSTIRKQVA---LYFRGHKEENGAAAHFPSAALPAPAFFT 132
Query: 253 ------PRVRELLLDALSPE-QLVLTLLEAEP--PHVLISRPSAPFTEASMMMSLTKLAD 303
P EL + +PE Q +++L + P PH + P + A+ S+ + A
Sbjct: 133 AVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVAT--ESVCESAA 190
Query: 304 KELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGL-MWRSIDHPGKLIFAPDLVL 362
+ L I WAK +P F LSL DQ+ LLE W E+ ++G+ W L+ +
Sbjct: 191 RLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNG 250
Query: 363 DRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADS 422
D + + + I+ L +RFR+L+L E+ C+K ++ + S
Sbjct: 251 DNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKA---------VPTHS 301
Query: 423 SRKLAHLLNAVTDALVWVIAKSGISS------QQQSMRLANLLMLLSHVR 466
+L NA A + A+ ++S Q R LL+LL +R
Sbjct: 302 GSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALR 351
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.132 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,259,879
Number of Sequences: 37866
Number of extensions: 962674
Number of successful extensions: 2494
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 2197
Number of HSP's gapped (non-prelim): 217
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.