Search of human proteins with 94421471

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94421471 ring finger protein 17 [Homo sapiens]
         (1623 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94421471 ring finger protein 17 [Homo sapiens]                    3283   0.0  
gi|38505161 tudor domain containing 1 [Homo sapiens]                  119   2e-26
gi|145312259 tudor and KH domain containing isoform a [Homo sapi...    70   2e-11
gi|145312246 tudor and KH domain containing isoform b [Homo sapi...    70   2e-11
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...    70   2e-11
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...    70   2e-11
gi|58197558 tudor domain containing 6 [Homo sapiens]                   69   4e-11
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho...    65   5e-10
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho...    65   5e-10
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho...    65   5e-10
gi|112293287 tudor domain containing 7 [Homo sapiens]                  64   1e-09
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          61   8e-09
gi|77404397 staphylococcal nuclease domain containing 1 [Homo sa...    56   2e-07
gi|40255178 tudor domain containing 5 [Homo sapiens]                   55   6e-07
gi|166851804 tudor domain containing 9 [Homo sapiens]                  51   1e-05
gi|210147600 tripartite motif-containing 64 [Homo sapiens]             41   0.011
gi|31542779 tripartite motif family-like 1 [Homo sapiens]              40   0.018
gi|119220603 ring finger protein 208 [Homo sapiens]                    40   0.024
gi|209862805 SPRY domain containing 5 [Homo sapiens]                   39   0.041
gi|221219026 pleckstrin homology-like domain, family B, member 1...    37   0.20 
gi|221219024 pleckstrin homology-like domain, family B, member 1...    37   0.20 
gi|38424073 pleckstrin homology-like domain, family B, member 1 ...    37   0.20 
gi|31377566 ring finger protein 168 [Homo sapiens]                     37   0.20 
gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]       37   0.20 
gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]        37   0.20 
gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]       37   0.20 
gi|24432013 zinc finger protein 668 [Homo sapiens]                     36   0.35 
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]          35   0.45 
gi|109637791 transcription factor-like nuclear regulator [Homo s...    35   0.45 
gi|226442736 ring finger protein 222 [Homo sapiens]                    35   0.59 

>gi|94421471 ring finger protein 17 [Homo sapiens]
          Length = 1623

 Score = 3283 bits (8512), Expect = 0.0
 Identities = 1623/1623 (100%), Positives = 1623/1623 (100%)

Query: 1    MAAEASKTGPSRSSYQRMGRKSQPWGAAEIQCTRCGRRVSRSSGHHCELQCGHAFCELCL 60
            MAAEASKTGPSRSSYQRMGRKSQPWGAAEIQCTRCGRRVSRSSGHHCELQCGHAFCELCL
Sbjct: 1    MAAEASKTGPSRSSYQRMGRKSQPWGAAEIQCTRCGRRVSRSSGHHCELQCGHAFCELCL 60

Query: 61   LMTEECTTIICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKTIKNCSQDFKKTADQ 120
            LMTEECTTIICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKTIKNCSQDFKKTADQ
Sbjct: 61   LMTEECTTIICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKTIKNCSQDFKKTADQ 120

Query: 121  LTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGKALEHMQKQTI 180
            LTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGKALEHMQKQTI
Sbjct: 121  LTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGKALEHMQKQTI 180

Query: 181  EERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYIEEKKNNLNAA 240
            EERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYIEEKKNNLNAA
Sbjct: 181  EERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYIEEKKNNLNAA 240

Query: 241  MNIARALQLSPSLRTYCDLNQIIRTLQLTSDSELAQVSSPQLRNPPRLSVNCSEIICMFN 300
            MNIARALQLSPSLRTYCDLNQIIRTLQLTSDSELAQVSSPQLRNPPRLSVNCSEIICMFN
Sbjct: 241  MNIARALQLSPSLRTYCDLNQIIRTLQLTSDSELAQVSSPQLRNPPRLSVNCSEIICMFN 300

Query: 301  NMGKIEFRDSTKCYPQENEIRQNVQKKYNNKKELSCYDTYPPLEKKKVDMSVLTSEAPPP 360
            NMGKIEFRDSTKCYPQENEIRQNVQKKYNNKKELSCYDTYPPLEKKKVDMSVLTSEAPPP
Sbjct: 301  NMGKIEFRDSTKCYPQENEIRQNVQKKYNNKKELSCYDTYPPLEKKKVDMSVLTSEAPPP 360

Query: 361  PLQPETNDVHLEAKNFQPQKDVATASPKTIAVLPQMGSSPDVIIEEIIEDNVESSAELVF 420
            PLQPETNDVHLEAKNFQPQKDVATASPKTIAVLPQMGSSPDVIIEEIIEDNVESSAELVF
Sbjct: 361  PLQPETNDVHLEAKNFQPQKDVATASPKTIAVLPQMGSSPDVIIEEIIEDNVESSAELVF 420

Query: 421  VSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGARIFVSSIKNGMW 480
            VSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGARIFVSSIKNGMW
Sbjct: 421  VSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGARIFVSSIKNGMW 480

Query: 481  CRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFMVDFGNSEVLIVTGVVDTHVRPEH 540
            CRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFMVDFGNSEVLIVTGVVDTHVRPEH
Sbjct: 481  CRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFMVDFGNSEVLIVTGVVDTHVRPEH 540

Query: 541  SAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIVPQNSNEGWEEEAKVEFLK 600
            SAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIVPQNSNEGWEEEAKVEFLK
Sbjct: 541  SAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIVPQNSNEGWEEEAKVEFLK 600

Query: 601  MVNNKAVSMKVFREEDGVLIVDLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHF 660
            MVNNKAVSMKVFREEDGVLIVDLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHF
Sbjct: 601  MVNNKAVSMKVFREEDGVLIVDLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHF 660

Query: 661  EKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGE 720
            EKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGE
Sbjct: 661  EKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGE 720

Query: 721  NLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDE 780
            NLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDE
Sbjct: 721  NLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDE 780

Query: 781  FLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELF 840
            FLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELF
Sbjct: 781  FLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELF 840

Query: 841  DSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPV 900
            DSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPV
Sbjct: 841  DSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPV 900

Query: 901  SAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEP 960
            SAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEP
Sbjct: 901  SAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEP 960

Query: 961  VKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKT 1020
            VKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKT
Sbjct: 961  VKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKT 1020

Query: 1021 MGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKI 1080
            MGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKI
Sbjct: 1021 MGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKI 1080

Query: 1081 FCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTN 1140
            FCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTN
Sbjct: 1081 FCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTN 1140

Query: 1141 FDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVP 1200
            FDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVP
Sbjct: 1141 FDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVP 1200

Query: 1201 KLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGAVRVQ 1260
            KLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGAVRVQ
Sbjct: 1201 KLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGAVRVQ 1260

Query: 1261 YLDHGFTEKIPQCHLYPILLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQV 1320
            YLDHGFTEKIPQCHLYPILLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQV
Sbjct: 1261 YLDHGFTEKIPQCHLYPILLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQV 1320

Query: 1321 DIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEEE 1380
            DIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEEE
Sbjct: 1321 DIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEEE 1380

Query: 1381 QWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQS 1440
            QWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQS
Sbjct: 1381 QWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQS 1440

Query: 1441 NQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKI 1500
            NQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKI
Sbjct: 1441 NQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKI 1500

Query: 1501 VAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE 1560
            VAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE
Sbjct: 1501 VAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE 1560

Query: 1561 TRIPYCPKWSMEALWAMIDCLQGKQLYAVSMAPAPEQIVTLYDDEQHPVHMPLVEMGLAD 1620
            TRIPYCPKWSMEALWAMIDCLQGKQLYAVSMAPAPEQIVTLYDDEQHPVHMPLVEMGLAD
Sbjct: 1561 TRIPYCPKWSMEALWAMIDCLQGKQLYAVSMAPAPEQIVTLYDDEQHPVHMPLVEMGLAD 1620

Query: 1621 KDE 1623
            KDE
Sbjct: 1621 KDE 1623


>gi|38505161 tudor domain containing 1 [Homo sapiens]
          Length = 1189

 Score =  119 bits (299), Expect = 2e-26
 Identities = 173/782 (22%), Positives = 306/782 (39%), Gaps = 83/782 (10%)

Query: 571  PLAQPCSLKDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKV---FREEDGVLIVDLQKPP 627
            P A  C + +++P   N  W  +       ++  +  S+K+     EE     V+++ P 
Sbjct: 374  PCAIKCFVANVIPAEGN--WSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPN 431

Query: 628  PNKISSDMPVSLRDALVFMELAKFKSQSLRSHFE-------KNTTLHYHPPILPKEMT-- 678
              K+   + + +   L        K  + +S  E       +N  +     ++PK +T  
Sbjct: 432  SGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLN 491

Query: 679  ---DVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVA 735
               +    V HI +P DF+ Q ++    L  L+     Y  +     +    + D  C  
Sbjct: 492  VGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551

Query: 736  KFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAY 795
              ED  WYRA V+     + V V YVD+GN   +++  +  I  + L  P +AIKC LA 
Sbjct: 552  FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611

Query: 796  IEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSIND 855
            ++P      W+ EA    ++  Q+K +T  V+  LE N  LVEL D    P +   S++ 
Sbjct: 612  VKPSLGI--WTPEAICLMKKLVQNKIITVKVVDKLE-NSSLVELIDKSETPHV---SVSK 665

Query: 856  QLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYN 915
             L+  G A  E   +    + K  +V + S    +  +V   NP+    +     +   +
Sbjct: 666  VLLDAGFAVGEQSMV----TDKPSDVKETSVPLGVEGKV---NPLEWTWV-----ELGVD 713

Query: 916  KELPVHICNVISPEKIYVQWLLTENL--LNSLEEKMIAAYENSKWEPVKWENDMHCAVKI 973
            + + V +C + SP + Y   L  + L  LN L + +    +       K E    C    
Sbjct: 714  QTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFF 773

Query: 974  QDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDI 1033
                 W R  +  ++ +  V+V   D G    V  D LR +      +    + C L DI
Sbjct: 774  AGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADI 833

Query: 1034 RPAGGSDKWTATACDCLSLYLTGAVATIILQ---VDSEENNTTWPLPVKIFCRDEKGERV 1090
            +    +  W+  A     +     VA I LQ   V+  EN     L     C       V
Sbjct: 834  Q--SRNKHWSEEAITRFQM----CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDV 887

Query: 1091 DVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTNFDPDKKTADI 1150
             + ++L+ K  +  +    +L N   +++  L+V ++   +       T+     KT ++
Sbjct: 888  LIDEHLVLKSASPHK----DLPNDRLVNKHELQVHVQGLQA-------TSSAEQWKTIEL 936

Query: 1151 ISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKM 1210
              ++ +   Q  +LE           I + N+F A    + +          ++ +L  +
Sbjct: 937  PVDKTI---QANVLE-----------IISPNLFYALPKGMPE----------NQEKLCML 972

Query: 1211 TNEIQSNLKCLGLLEPYFWKKGEACAVR-GSDTLWYRGKVMEVVGGAVRVQYLDHGFTEK 1269
            T E+           PY  + G+AC  +  SD  WYR  V+      V V Y D+G  E 
Sbjct: 973  TAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIET 1032

Query: 1270 IPQCHLYPIL-LYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELP 1328
            +P C + PI   +  +P   I C L     +        I +L+  +  + V + +  + 
Sbjct: 1033 LPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGIT 1092

Query: 1329 KN 1330
            KN
Sbjct: 1093 KN 1094



 Score =  116 bits (290), Expect = 2e-25
 Identities = 191/899 (21%), Positives = 354/899 (39%), Gaps = 123/899 (13%)

Query: 675  KEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACV 734
            K+  ++  TV     PGDFY+QL     + ++ +      ++    + +   PV+ + C+
Sbjct: 261  KKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCI 320

Query: 735  AKFE-DGIWYRAKVIGLPGHQE-VEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCK 792
            AK+  D  W RA +  +   Q+   V Y+D+GN   I +  +  +       P  AIKC 
Sbjct: 321  AKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCF 380

Query: 793  LAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTS 852
            +A + P +    WS +  +  +    +++ +  ++ ILE+              E+ T +
Sbjct: 381  VANVIPAEG--NWSSDCIKATKPLLMEQYCSIKIVDILEE--------------EVVTFA 424

Query: 853  INDQLVKEGL----ASYEIGYILKDNSQ--KHIEVWDPSPEEIISNEVHNLNPVSAKSLP 906
            +  +L   G        E+GY LK + Q  K        PE++      N   V    L 
Sbjct: 425  VEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLI 484

Query: 907  NENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKW-EPVKWEN 965
             +        E    + ++ +PE  + Q L +   L  L+  +      SK+ + +   +
Sbjct: 485  PKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASL------SKYCDQLPPRS 538

Query: 966  DMH------CAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLK 1019
            D +      C  +  + +QW R  ++   ++  V V   D G   ++++  L  +   L 
Sbjct: 539  DFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLL 598

Query: 1020 TMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVK 1079
             +   +++C L  ++P+ G   WT  A  CL   L       +  VD  EN++     V+
Sbjct: 599  ELPMQAIKCVLAGVKPSLGI--WTPEAI-CLMKKLVQNKIITVKVVDKLENSSL----VE 651

Query: 1080 IFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLE-QEDSVVTNCIK 1138
            +  + E    V VSK L+  G A+ E+ +   D    + E S+ + +E + + +    ++
Sbjct: 652  LIDKSET-PHVSVSKVLLDAGFAVGEQSMVT-DKPSDVKETSVPLGVEGKVNPLEWTWVE 709

Query: 1139 TNFDPDKKTADII--SEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTI 1196
               D   +T D++        EF   +L        K  A+  +N    +          
Sbjct: 710  LGVD---QTVDVVVCVIYSPGEFYCHVL--------KEDALKKLNDLNKS---------- 748

Query: 1197 FVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVV-GG 1255
                 L+E    K+ N  ++ +      +P        CA    D  WYR  V E++  G
Sbjct: 749  -----LAEHCQQKLPNGFKAEIG-----QP-------CCAFFAGDGSWYRALVKEILPNG 791

Query: 1256 AVRVQYLDHGFTEKIPQCHLYPI-LLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQL 1314
             V+V ++D+G  E++    L  I   + ++P   I CQL +       W  +AI   Q  
Sbjct: 792  HVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMC 851

Query: 1315 LSKRQVDIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSD-- 1372
            ++  ++   ++E+ +N      I +    +S  Y          EH   +    P  D  
Sbjct: 852  VAGIKLQARVVEVTEN-----GIGVELTDLSTCYPRIISDVLIDEHL-VLKSASPHKDLP 905

Query: 1373 HDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLD 1432
            +D+   + + ++  + L +    T     + +  LP    + A  V  ++SPN  Y    
Sbjct: 906  NDRLVNKHELQVHVQGLQA----TSSAEQWKTIELPVDKTIQA-NVLEIISPNLFY---- 956

Query: 1433 SIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEY-D 1491
            ++      NQ           E       E L+  N   ++ PP    R    C A+Y  
Sbjct: 957  ALPKGMPENQ-----------EKLCMLTAELLEYCNAP-KSRPPYRP-RIGDACCAKYTS 1003

Query: 1492 DGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAG 1550
            D  WYRA ++   +     + V + DYG+   L L R+  I S  +  P + I+  L G
Sbjct: 1004 DDFWYRAVVLGTSD---TDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEG 1059



 Score = 94.7 bits (234), Expect = 6e-19
 Identities = 139/550 (25%), Positives = 234/550 (42%), Gaps = 84/550 (15%)

Query: 523  SEVLIVTGVVDTHVRPEHSAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIV 582
            SE  ++ G VD      +   + ++L  LC ++ K        L ++   A  C L  + 
Sbjct: 568  SEESVLVGYVD------YGNFEILSLMRLCPIIPK--------LLELPMQAIKCVLAGVK 613

Query: 583  PQNSNEGWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIVDL--QKPPPNKISSDMPVSLR 640
            P  S   W  EA     K+V NK +++KV  + +   +V+L  +   P+   S + +   
Sbjct: 614  P--SLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAG 671

Query: 641  DALVFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMT--------DVSVTVCHINSPGD 692
             A+    +   K   ++   E +  L     + P E T         V V VC I SPG+
Sbjct: 672  FAVGEQSMVTDKPSDVK---ETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGE 728

Query: 693  FYLQLIEGLDILFLLKTIEEFY------KSEDGENLEILCPVQDQACVAKFE-DGIWYRA 745
            FY  +++  D L  L  + +        K  +G   EI      Q C A F  DG WYRA
Sbjct: 729  FYCHVLKE-DALKKLNDLNKSLAEHCQQKLPNGFKAEI-----GQPCCAFFAGDGSWYRA 782

Query: 746  KVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQW 805
             V  +  +  V+V +VD+GN  ++T  ++R I   FLN P + I+C+LA I+   R   W
Sbjct: 783  LVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQ--SRNKHW 840

Query: 806  SKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFD-SLGAPEMTTTSINDQLVKEGLAS 864
            S+EA  +F+       +   V+++ E N + VEL D S   P +    I+D L+ E L  
Sbjct: 841  SEEAITRFQMCVAGIKLQARVVEVTE-NGIGVELTDLSTCYPRI----ISDVLIDEHL-- 893

Query: 865  YEIGYILKDNSQKHIEVWDPSPEEIISNEVH-NLNPVSAKSLPNE--NFQSLYNKELPVH 921
                 +LK ++  H ++  P+   +  +E+  ++  + A S   +    +   +K +  +
Sbjct: 894  -----VLK-SASPHKDL--PNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQAN 945

Query: 922  ICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKW-------EPVKWENDMHCAVKIQ 974
            +  +ISP   Y    L + +  + E+  +   E  ++        P +      C  K  
Sbjct: 946  VLEIISPNLFYA---LPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYT 1002

Query: 975  DKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSL-----ECS 1029
              + W R  ++   +DT VEVL  D G     N++ L        T   L+L      CS
Sbjct: 1003 SDDFWYRA-VVLGTSDTDVEVLYADYG-----NIETLPLCRVQPITSSHLALPFQIIRCS 1056

Query: 1030 LVDIRPAGGS 1039
            L  +    GS
Sbjct: 1057 LEGLMELNGS 1066



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 123/513 (23%), Positives = 220/513 (42%), Gaps = 74/513 (14%)

Query: 1126 LEQEDSVVTNCIKTNFDPDKKTADIISEQKVSEFQEKIL--EPRTTRGYKPPAIPNMNVF 1183
            LE + S+ T  ++ N   +K    +   ++++ + E+I+  + R+ +  K   I      
Sbjct: 216  LENKSSIETKDVEVN---NKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEI------ 266

Query: 1184 EATVSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCLGLL---EPYFWKKGEACAVRGS 1240
            + TV+     G  +V  +L   E+++  N++ ++LK        + Y   KGE C  + +
Sbjct: 267  KGTVTEFKHPGDFYV--QLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYT 324

Query: 1241 -DTLWYRGKV--MEVVGGAVRVQYLDHGFTEKIPQCHLYPILLYPDI-PQFCIPCQLHNT 1296
             D  W R  +  ++V      V Y+D+G  E IP   +Y +    D+ P   I C + N 
Sbjct: 325  VDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANV 384

Query: 1297 TPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPWEKLSIHLYF--DGMSLSYFMAYYK 1354
             P    W  D I+  + LL ++   I I+++ +      ++ +     G  L + +    
Sbjct: 385  IPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMG 444

Query: 1355 YCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELY 1414
            Y      ++  KE      D+   E+  ++  E  +  +  + L+P  L+ ++   G+ +
Sbjct: 445  YGLKPSGQDSKKENA----DQSDPEDVGKMTTENNIVVDK-SDLIPKVLTLNV---GDEF 496

Query: 1415 AVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEAL 1474
               V H+ +P + +          Q  Q                 L E    ++K  + L
Sbjct: 497  CGVVAHIQTPEDFFC---------QQLQ-------------SGRKLAELQASLSKYCDQL 534

Query: 1475 PPLTDFRTEMP--CLAEY-DDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQ 1531
            PP +DF   +   C A++ +D  WYRA ++A       S+LV +VDYG+   L+L RLC 
Sbjct: 535  PPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEE--SVLVGYVDYGNFEILSLMRLCP 592

Query: 1532 IPSHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEALWAMIDCLQGKQLYAVSM 1591
            I   L+  P +AIK +LAG KP L             W+ EA+  M   +Q K +  V +
Sbjct: 593  IIPKLLELPMQAIKCVLAGVKPSL-----------GIWTPEAICLMKKLVQNK-IITVKV 640

Query: 1592 APAPE--QIVTLYDDEQHP---VHMPLVEMGLA 1619
                E   +V L D  + P   V   L++ G A
Sbjct: 641  VDKLENSSLVELIDKSETPHVSVSKVLLDAGFA 673



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 145/676 (21%), Positives = 257/676 (38%), Gaps = 107/676 (15%)

Query: 928  PEKIYVQWLLTENL--LNSLEEKMIAAYEN---SKWEPVKWENDMHCAVKIQDKNQWRRG 982
            P   YVQ   +E L  +N L   +   Y N     + PVK E    C  K      W R 
Sbjct: 276  PGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEV---CIAKYTVDQTWNRA 332

Query: 983  QIIRM-VTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDK 1041
             I  + V      VL  D G E ++ ++ +  L  N+      +++C + ++ PA G+  
Sbjct: 333  IIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGN-- 390

Query: 1042 WTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGL 1101
            W++         L     +I +    EE   T+ + V++      G+ +D    LI+ G 
Sbjct: 391  WSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVEL---PNSGKLLD--HVLIEMGY 445

Query: 1102 ALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTNFDPDKKTADIISEQKVSEFQE 1161
             L+    ++   +   S+      +  E+++V +  K++  P   T ++  E        
Sbjct: 446  GLKPSGQDSKKENADQSDPEDVGKMTTENNIVVD--KSDLIPKVLTLNVGDE-------- 495

Query: 1162 KILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCL 1221
                                 F   V+ +      F     S  +L ++   +      L
Sbjct: 496  ---------------------FCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQL 534

Query: 1222 GLLEPYFWKKGEACAVRGS-DTLWYRGKVMEVVGG-AVRVQYLDHGFTEKIPQCHLYPIL 1279
                 ++   G+ C  + S D  WYR  V+      +V V Y+D+G  E +    L PI+
Sbjct: 535  PPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPII 594

Query: 1280 -LYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIME-LPKNPWEKLSI 1337
                ++P   I C L    P   +W P+AI ++++L+  + + + +++ L  +   +L  
Sbjct: 595  PKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELID 654

Query: 1338 HLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYE-EEQWEIRFEELLSAETDT 1396
                  +S+S  +    +   E  + M+ +KP    +       + ++   E    E   
Sbjct: 655  KSETPHVSVSKVLLDAGFAVGE--QSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGV 712

Query: 1397 PLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESE 1456
                  +   + SPGE Y   +K            D+++  N  N+              
Sbjct: 713  DQTVDVVVCVIYSPGEFYCHVLKE-----------DALKKLNDLNK-------------- 747

Query: 1457 SESLDEALQRVNKKVEALPPLTDFRTEM--PCLAEY-DDGLWYRAKIVAIKEFNPLS-IL 1512
              SL E  Q      + LP    F+ E+  PC A +  DG WYRA    +KE  P   + 
Sbjct: 748  --SLAEHCQ------QKLP--NGFKAEIGQPCCAFFAGDGSWYRA---LVKEILPNGHVK 794

Query: 1513 VQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSME 1572
            V FVDYG+  ++T + L  I S  +  P + I+  LA  +   +            WS E
Sbjct: 795  VHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNK-----------HWSEE 843

Query: 1573 ALWAMIDCLQGKQLYA 1588
            A+     C+ G +L A
Sbjct: 844  AITRFQMCVAGIKLQA 859


>gi|145312259 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 6/137 (4%)

Query: 680 VSVTVCHINSPGDFYLQLI--EGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
           + V V     P  F++Q++    L +  L+  + + Y++   E+L +   V D       
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTV--HVGDIVAAPLP 365

Query: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIE 797
            +G WYRA+V+G   +  +++ +VDFG+     +KD+R ++ +FL+ P +AI+C LA I 
Sbjct: 366 TNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425

Query: 798 PYKRTMQWSKEAKEKFE 814
           P     QW +EA ++F+
Sbjct: 426 P--SGDQWEEEALDEFD 440



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 19/232 (8%)

Query: 882  WD-PSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN 940
            W+ PS +    +E   +  +    +P+ +F    ++ L V++     P   ++Q + + +
Sbjct: 271  WEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS 330

Query: 941  L-LNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999
            L L+ L  +M   YENS  E +        A  +     W R +++  + +  +++   D
Sbjct: 331  LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVD 390

Query: 1000 VGVELVVNVDC----LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS-LYL 1054
             G     N DC    LR L  +  ++   ++ECSL  I P+G  D+W   A D    L  
Sbjct: 391  FGD----NGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG--DQWEEEALDEFDRLTH 444

Query: 1055 TGAVATIILQVDS--EENNTTWPLPVKIFCRD-EKGERVDVSKYLIKKGLAL 1103
                  ++ ++ S  +   +TWP   KI+  D   G+++D+   L+ KG A+
Sbjct: 445  CADWKPLVAKISSYVQTGISTWP---KIYLYDTSNGKKLDIGLELVHKGYAI 493



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 10/123 (8%)

Query: 1455 SESESLDEALQRVNKKVEALPP--LTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSIL 1512
            S S  LD+ +  + +  E   P  LT    ++       +G WYRA+++   E   L + 
Sbjct: 328  SRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDL- 386

Query: 1513 VQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE------TRIPYC 1566
              FVD+G      L  L  + S  +  P +AI+  LA   P      E       R+ +C
Sbjct: 387  -YFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHC 445

Query: 1567 PKW 1569
              W
Sbjct: 446  ADW 448


>gi|145312246 tudor and KH domain containing isoform b [Homo
           sapiens]
          Length = 516

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 6/137 (4%)

Query: 680 VSVTVCHINSPGDFYLQLI--EGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
           + V V     P  F++Q++    L +  L+  + + Y++   E+L +   V D       
Sbjct: 263 LEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTV--HVGDIVAAPLP 320

Query: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIE 797
            +G WYRA+V+G   +  +++ +VDFG+     +KD+R ++ +FL+ P +AI+C LA I 
Sbjct: 321 TNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 380

Query: 798 PYKRTMQWSKEAKEKFE 814
           P     QW +EA ++F+
Sbjct: 381 P--SGDQWEEEALDEFD 395



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 19/232 (8%)

Query: 882  WD-PSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN 940
            W+ PS +    +E   +  +    +P+ +F    ++ L V++     P   ++Q + + +
Sbjct: 226  WEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS 285

Query: 941  L-LNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999
            L L+ L  +M   YENS  E +        A  +     W R +++  + +  +++   D
Sbjct: 286  LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVD 345

Query: 1000 VGVELVVNVDC----LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS-LYL 1054
             G     N DC    LR L  +  ++   ++ECSL  I P+G  D+W   A D    L  
Sbjct: 346  FGD----NGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG--DQWEEEALDEFDRLTH 399

Query: 1055 TGAVATIILQVDS--EENNTTWPLPVKIFCRD-EKGERVDVSKYLIKKGLAL 1103
                  ++ ++ S  +   +TWP   KI+  D   G+++D+   L+ KG A+
Sbjct: 400  CADWKPLVAKISSYVQTGISTWP---KIYLYDTSNGKKLDIGLELVHKGYAI 448



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 10/123 (8%)

Query: 1455 SESESLDEALQRVNKKVEALPP--LTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSIL 1512
            S S  LD+ +  + +  E   P  LT    ++       +G WYRA+++   E   L + 
Sbjct: 283  SRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDL- 341

Query: 1513 VQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE------TRIPYC 1566
              FVD+G      L  L  + S  +  P +AI+  LA   P      E       R+ +C
Sbjct: 342  -YFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHC 400

Query: 1567 PKW 1569
              W
Sbjct: 401  ADW 403


>gi|145312270 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 6/137 (4%)

Query: 680 VSVTVCHINSPGDFYLQLI--EGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
           + V V     P  F++Q++    L +  L+  + + Y++   E+L +   V D       
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTV--HVGDIVAAPLP 365

Query: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIE 797
            +G WYRA+V+G   +  +++ +VDFG+     +KD+R ++ +FL+ P +AI+C LA I 
Sbjct: 366 TNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425

Query: 798 PYKRTMQWSKEAKEKFE 814
           P     QW +EA ++F+
Sbjct: 426 P--SGDQWEEEALDEFD 440



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 19/232 (8%)

Query: 882  WD-PSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN 940
            W+ PS +    +E   +  +    +P+ +F    ++ L V++     P   ++Q + + +
Sbjct: 271  WEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS 330

Query: 941  L-LNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999
            L L+ L  +M   YENS  E +        A  +     W R +++  + +  +++   D
Sbjct: 331  LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVD 390

Query: 1000 VGVELVVNVDC----LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS-LYL 1054
             G     N DC    LR L  +  ++   ++ECSL  I P+G  D+W   A D    L  
Sbjct: 391  FGD----NGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG--DQWEEEALDEFDRLTH 444

Query: 1055 TGAVATIILQVDS--EENNTTWPLPVKIFCRD-EKGERVDVSKYLIKKGLAL 1103
                  ++ ++ S  +   +TWP   KI+  D   G+++D+   L+ KG A+
Sbjct: 445  CADWKPLVAKISSYVQTGISTWP---KIYLYDTSNGKKLDIGLELVHKGYAI 493



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 10/123 (8%)

Query: 1455 SESESLDEALQRVNKKVEALPP--LTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSIL 1512
            S S  LD+ +  + +  E   P  LT    ++       +G WYRA+++   E   L + 
Sbjct: 328  SRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDL- 386

Query: 1513 VQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE------TRIPYC 1566
              FVD+G      L  L  + S  +  P +AI+  LA   P      E       R+ +C
Sbjct: 387  -YFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHC 445

Query: 1567 PKW 1569
              W
Sbjct: 446  ADW 448


>gi|145312256 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 6/137 (4%)

Query: 680 VSVTVCHINSPGDFYLQLI--EGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
           + V V     P  F++Q++    L +  L+  + + Y++   E+L +   V D       
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTV--HVGDIVAAPLP 365

Query: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIE 797
            +G WYRA+V+G   +  +++ +VDFG+     +KD+R ++ +FL+ P +AI+C LA I 
Sbjct: 366 TNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425

Query: 798 PYKRTMQWSKEAKEKFE 814
           P     QW +EA ++F+
Sbjct: 426 P--SGDQWEEEALDEFD 440



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 19/232 (8%)

Query: 882  WD-PSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN 940
            W+ PS +    +E   +  +    +P+ +F    ++ L V++     P   ++Q + + +
Sbjct: 271  WEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS 330

Query: 941  L-LNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999
            L L+ L  +M   YENS  E +        A  +     W R +++  + +  +++   D
Sbjct: 331  LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVD 390

Query: 1000 VGVELVVNVDC----LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS-LYL 1054
             G     N DC    LR L  +  ++   ++ECSL  I P+G  D+W   A D    L  
Sbjct: 391  FGD----NGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG--DQWEEEALDEFDRLTH 444

Query: 1055 TGAVATIILQVDS--EENNTTWPLPVKIFCRD-EKGERVDVSKYLIKKGLAL 1103
                  ++ ++ S  +   +TWP   KI+  D   G+++D+   L+ KG A+
Sbjct: 445  CADWKPLVAKISSYVQTGISTWP---KIYLYDTSNGKKLDIGLELVHKGYAI 493



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 10/123 (8%)

Query: 1455 SESESLDEALQRVNKKVEALPP--LTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSIL 1512
            S S  LD+ +  + +  E   P  LT    ++       +G WYRA+++   E   L + 
Sbjct: 328  SRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDL- 386

Query: 1513 VQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE------TRIPYC 1566
              FVD+G      L  L  + S  +  P +AI+  LA   P      E       R+ +C
Sbjct: 387  -YFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHC 445

Query: 1567 PKW 1569
              W
Sbjct: 446  ADW 448


>gi|58197558 tudor domain containing 6 [Homo sapiens]
          Length = 2096

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 125/524 (23%), Positives = 211/524 (40%), Gaps = 96/524 (18%)

Query: 409  EDNVESSAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGA 468
            E  V S+ E V VS+V +P +F+ +    I+  K L   +  +C  ++     + L   A
Sbjct: 767  ELEVGSTVE-VRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLA 825

Query: 469  RIFVSSIKNGMWCRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFMVDFGNSEVLIV 528
            +  V    N  W R  I+ +  +E  N                   +  VD+G+ E++  
Sbjct: 826  KRTV----NRQWSRALISGIQSVEHVN-------------------VTFVDYGDREMV-- 860

Query: 529  TGVVDTHVRPEHSAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIVP-QNSN 587
                        S K   ++++  L + K++ +   L   IQP+ Q   + D+   Q  N
Sbjct: 861  ------------SVKNIYSISEEFLKV-KAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFN 907

Query: 588  E----GWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIVDLQKPPPNKISSDMPVSLRDAL 643
            E     W++  +++   +    +++ ++F       IVDL  P             + A 
Sbjct: 908  EFIDNAWQKNLELK-CTIFALASINEELFN------IVDLLTP------------FQSAC 948

Query: 644  VFM-ELAKFKSQSLRSHFEKNTTLH--YHPPILPKEMTDVSVTVCHINSPGDFYLQLIEG 700
             F+ E    +   L+   E +  LH  ++     K  ++  V + HI+ P  FY QL   
Sbjct: 949  HFLVEKRLARPVKLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFYCQLARN 1008

Query: 701  LDILFLLK-TIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVK 759
             +IL  L  +I +  K         L P     C+AK+ DG WYR  VI     +  +V 
Sbjct: 1009 ANILEQLSCSITQLSKVLLNLKTSPLNP--GTLCLAKYTDGNWYRGIVI---EKEPKKVF 1063

Query: 760  YVDFGNTAKITIKDVRKIKD---EFLNAPEKAIKCKLAYIEPY--KRTMQWSKEAKEKFE 814
            +VDFGN   +T  D+  I     + L  P +A++C L+ I  +  +  + W       F+
Sbjct: 1064 FVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDIPDHIPEEVVVW-------FQ 1116

Query: 815  EKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGLASYEIGYILKDN 874
            E   DK +   V+    D  L++EL+   G     + SIN +L   GL SY      KD 
Sbjct: 1117 ETILDKSLKALVVAKDPDGTLIIELY---GDNIQISASINKKL---GLLSY------KDR 1164

Query: 875  SQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKEL 918
             +K       S  E +  +  N+     + L       L NKE+
Sbjct: 1165 IRKKESEVLCSTTETLEEKNENMKLPCTEYLSKSVGYKLPNKEI 1208



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 72/304 (23%), Positives = 133/304 (43%), Gaps = 21/304 (6%)

Query: 575 PCSLKDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKV--FREEDGVLIVDLQKPPP---N 629
           PC+L  +   +   GW      +   ++  KAV+ K+  +   + V  V L        N
Sbjct: 375 PCALYGL--WDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLN 432

Query: 630 KISSDMPVSLRDALVFMELAK------FKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVT 683
           ++       L D ++  +  +       +SQS     ++  +L     I  K        
Sbjct: 433 RVFGVQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFYDAQ 492

Query: 684 VCHINSPGDFYLQLIE-GLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIW 742
           V  + +P +F+++L +  +    L++ +  FY S    +  +L P  D  C  K+++  +
Sbjct: 493 VEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENGY 552

Query: 743 YRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRT 802
           YRA V  L   + V+V  VD GN+  +   DVR +  +F   P  A+KC LA I P  +T
Sbjct: 553 YRAIVTKLDD-KSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKT 611

Query: 803 MQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGL 862
             WS+EA   F++    K +   ++   +D+  ++E+ D     E    +I+  + + G 
Sbjct: 612 --WSQEAVSFFKKTVLHKELVIHILD-KQDHQYVIEILDESRTGE---ENISKVIAQAGY 665

Query: 863 ASYE 866
           A Y+
Sbjct: 666 AKYQ 669



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 86/365 (23%), Positives = 149/365 (40%), Gaps = 51/365 (13%)

Query: 681  SVTVCHINSPGDFYLQLIEG-------LDILFLLKTIEEFYKSEDGENLEILCPVQDQAC 733
            +V V HIN   DFY+QLIE         + L  +KT  E+Y     +  +++C V     
Sbjct: 1308 TVYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFP--- 1364

Query: 734  VAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNA--PEKAIKC 791
                ED +WYRA +     +  + V+++D+GN + +    + ++  + +NA  P   I C
Sbjct: 1365 ----EDNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRL--DLVNAILPGLCIHC 1418

Query: 792  KLAYIE-PYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTT 850
             L   E P  +    SK+    F ++  +  + C  +K  +   ++  L D  G      
Sbjct: 1419 SLQGFEVPDNKN---SKKMMHYFSQRTSEAAIRCEFVKFQDRWEVI--LADEHGI----- 1468

Query: 851  TSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENF 910
              I D ++          Y L + SQ  +     S + I S    ++N     +    N+
Sbjct: 1469 --IADDMISR--------YALSEKSQVEL-----STQVIKSASSKSVNKSDIDTSVFLNW 1513

Query: 911  QSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYE----NSKWEPVKWEND 966
             +   K +  +   +  PE  + Q+  TE  L  LE ++  A E         P  +  D
Sbjct: 1514 YNPEKKMIRAYATVIDGPEYFWCQFADTEK-LQCLEVEVQTAGEQVADRRNCIPCPYIGD 1572

Query: 967  MHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVG-VELVVNVDCLRKLEENLKTMGRLS 1025
              C V+ ++   + R  I  +  D LV V L D G +E  V+   L  +   L ++   +
Sbjct: 1573 -PCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQA 1631

Query: 1026 LECSL 1030
              C L
Sbjct: 1632 FPCCL 1636



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 198/953 (20%), Positives = 340/953 (35%), Gaps = 149/953 (15%)

Query: 661  EKNTTLHYHPPILPKEMTDVSVT--VCHINSPGDFYLQLIE-GLDILFLLKTIEEFYKSE 717
            +K   L Y  P L   +T+  V   VCH   P   + QL     +I  L +++ + Y+  
Sbjct: 234  QKQPGLDYFYPQLQLGVTEAVVITQVCH---PHRIHCQLRSVSQEIHRLSESMAQVYRGS 290

Query: 718  DG-----------ENLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQE-VEVKYVDFGN 765
             G           E  E         C +   DG WYRA ++     Q   +V +VD+G 
Sbjct: 291  TGTGDENSTSATWEEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGR 350

Query: 766  TAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCS 825
               ++   +R +  E+   P     C L  +    R   WS+      +     K +   
Sbjct: 351  KELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGGRG--WSRSQVGDLKTLILGKAVNAK 408

Query: 826  VIKILE-DNVLLVELFDSLGAPEMTTTSINDQ-LVKEGLASYEIGYILKDNSQKHIEVWD 883
            +      ++V  V L+   G        +    L    L S        + SQ       
Sbjct: 409  IEFYCSFEHVYYVSLYGEDGINLNRVFGVQSCCLADRVLQSQATEEEEPETSQSQ----- 463

Query: 884  PSPEEIISNEVHNLNPVSAKSLPN-ENFQSLYNKELPVHICNVISPEKIYVQWLLTENLL 942
             SP E +  E+         SLP   + +   N      +  V +P + +++        
Sbjct: 464  -SPAEEVDEEI---------SLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTF 513

Query: 943  NSLEEKMIAAYEN-SKWEPV--KWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999
            + L  +M   Y + SK + V  K E D  C VK ++   +R   I+  + D  V+V L D
Sbjct: 514  SKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENGYYRA--IVTKLDDKSVDVFLVD 571

Query: 1000 VGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVA 1059
             G    V+   +R L    + +  L+++C+L DI P G +  W+  A       +     
Sbjct: 572  RGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKT--WSQEAVSFFKKTVLHKEL 629

Query: 1060 TIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALR---ERRINNLDNSHS 1116
             I + +D +++       ++I      GE  ++SK + + G A     E + N L N+HS
Sbjct: 630  VIHI-LDKQDHQYV----IEILDESRTGEE-NISKVIAQAGYAKYQEFETKENILVNAHS 683

Query: 1117 -------LSEKSLEVPL------------EQEDSVVTNCIKTNFDPDKKTADIISEQKVS 1157
                    + +S ++P             E + + V+  +         + +++ ++KV 
Sbjct: 684  PGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVK 743

Query: 1158 E------FQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMT 1211
                     +  LE +     K        V E  VS V + G  +     +   L  + 
Sbjct: 744  RASVYFPLMQNCLEIKPGSSSKGELEVGSTV-EVRVSYVENPGYFWCQLTRNIQGLKTLM 802

Query: 1212 NEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGA-VRVQYLDHGFTEKI 1270
            ++IQ    C     P+        A R  +  W R  +  +     V V ++D+G  E +
Sbjct: 803  SDIQ--YYCKNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMV 860

Query: 1271 PQCHLYPILL-YPDIPQFCIPCQLHNTT-PVGN---VWQPDAIEVLQQLLSKR-----QV 1320
               ++Y I   +  +      C L+N   PVG    VW   AI+   + +        ++
Sbjct: 861  SVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLEL 920

Query: 1321 DIHIMELPKNPWEKLSI-HLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEE 1379
               I  L     E  +I  L     S  +F+   +       ++ L+   +  H   Y  
Sbjct: 921  KCTIFALASINEELFNIVDLLTPFQSACHFLVEKRLARPVKLQKPLESSVQL-HSYFYST 979

Query: 1380 EQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQ 1439
               +I  EEL                          V + H+  P   Y  L       +
Sbjct: 980  HDMKIGSEEL--------------------------VYITHIDDPWTFYCQLARNANILE 1013

Query: 1440 SNQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAK 1499
                S T  S V               +N K   L P T       CLA+Y DG WYR  
Sbjct: 1014 QLSCSITQLSKVL--------------LNLKTSPLNPGT------LCLAKYTDGNWYRGI 1053

Query: 1500 IVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPS---HLMRYPARAIKVLLA 1549
            ++   E  P  +   FVD+G+   +T + L  IPS    ++  P +A++  L+
Sbjct: 1054 VI---EKEPKKVF--FVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLS 1101



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 59/220 (26%), Positives = 88/220 (40%), Gaps = 31/220 (14%)

Query: 1357 TSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAV 1416
            T+E  EE+  E P      + E    E +  +  S + D PL           PG    V
Sbjct: 1254 TTEKKEEISAETPLKT--ARVEATLSERKIGD--SCDKDLPLKFCEFPQKTIMPGFKTTV 1309

Query: 1417 QVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEAL-- 1474
             V H+   ++ Y+ L                   +  E+E   L E L  V  + E    
Sbjct: 1310 YVSHINDLSDFYVQL-------------------IEDEAEISHLSERLNSVKTRPEYYVG 1350

Query: 1475 PPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSIL-VQFVDYGSTAKLTLNRLCQIP 1533
            PPL   R +M C    +D LWYRA    IKE  P  +L VQF+DYG+ + +  N++ ++ 
Sbjct: 1351 PPLQ--RGDMICAVFPEDNLWYRA---VIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLD 1405

Query: 1534 SHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEA 1573
                  P   I   L GF+ P     +  + Y  + + EA
Sbjct: 1406 LVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQRTSEA 1445



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 80/349 (22%), Positives = 133/349 (38%), Gaps = 47/349 (13%)

Query: 1230 KKGEACAVRGSDTLWYRGKVMEVVGG--AVRVQYLDHGFTEKIPQCHL-YPILLYPDIPQ 1286
            K G  CA  G D  WYR  ++E        +V ++D+G  E +    L Y +  Y  +P 
Sbjct: 312  KPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPV 371

Query: 1287 FCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPWEKLSIHLYF-DGMS 1345
               PC L+     G  W    +  L+ L+  + V+  I E   +      + LY  DG++
Sbjct: 372  VTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKI-EFYCSFEHVYYVSLYGEDGIN 430

Query: 1346 LSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSS 1405
            L+        C ++   +           +  EEE+ E    +  + E D  +  P L S
Sbjct: 431  LNRVFGVQSCCLADRVLQ----------SQATEEEEPETSQSQSPAEEVDEEISLPALRS 480

Query: 1406 SLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQ 1465
                    Y  QV+ V +P+E +I L          +H+ T    +       S    L 
Sbjct: 481  IRLKMNAFYDAQVEFVKNPSEFWIRL---------RKHNVTFSKLMRRMCGFYSSASKLD 531

Query: 1466 RVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLT 1525
             V  K E          +  C  ++ +  +YRA    + + +  S+ V  VD G++  + 
Sbjct: 532  GVVLKPE---------PDDLCCVKWKENGYYRA---IVTKLDDKSVDVFLVDRGNSENVD 579

Query: 1526 LNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEAL 1574
               +  +     + P  A+K  LA   P    LG+T       WS EA+
Sbjct: 580  WYDVRMLLPQFRQLPILAVKCTLADIWP----LGKT-------WSQEAV 617



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 166/876 (18%), Positives = 312/876 (35%), Gaps = 125/876 (14%)

Query: 741  IWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPY- 799
            +W+R +V+     QE  V  +D G T       +   + EF N P + + C LA + P  
Sbjct: 80   LWHRCRVVSRQA-QESRVFLLDEGRTITAGAGSLAPGRREFFNLPSEVLGCVLAGLVPAG 138

Query: 800  ------KRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSI 853
                  +    W  +A +        +   C +  +L   ++L+E+ D           +
Sbjct: 139  CGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLVLLEVPD-----------V 187

Query: 854  NDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSL-PNENF-- 910
              Q+ + GLA      + +   ++++     S    + + V  L+ V  K   P  ++  
Sbjct: 188  FQQMRELGLARRVPDSLFRSLLERYLTAATAS----VGSGVPVLSRVPLKQKQPGLDYFY 243

Query: 911  -QSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSK-----------W 958
             Q        V I  V  P +I+ Q       ++ L E M   Y  S            W
Sbjct: 244  PQLQLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTSATW 303

Query: 959  EPVKWENDMH---CAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLE 1015
            E  +   D     CA    D + +R   +         +VL  D G + +V+   LR L 
Sbjct: 304  EEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLL 363

Query: 1016 ENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWP 1075
                 M  ++  C+L  +   G    W+ +    L   + G                   
Sbjct: 364  PEYFRMPVVTYPCALYGLWDGGRG--WSRSQVGDLKTLILGKAVNA-------------- 407

Query: 1076 LPVKIFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTN 1135
              ++ +C  E    V +     + G+ L   R+  +  S  L+++ L+    +E+   T+
Sbjct: 408  -KIEFYCSFEHVYYVSLYG---EDGINLN--RVFGVQ-SCCLADRVLQSQATEEEEPETS 460

Query: 1136 CIKTNFDPDKKTADIISEQKVSEFQEKILEP--RTTRGYKPPAIPNMNVF-EATVSCVGD 1192
                            S+    E  E+I  P  R+ R         MN F +A V  V +
Sbjct: 461  Q---------------SQSPAEEVDEEISLPALRSIR-------LKMNAFYDAQVEFVKN 498

Query: 1193 DGTIFVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKK--GEACAVRGSDTLWYRGKVM 1250
                ++  +       K+   +         L+    K    + C V+  +  +YR  V 
Sbjct: 499  PSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENGYYRAIVT 558

Query: 1251 EVVGGAVRVQYLDHGFTEKIPQCHLYPIL-LYPDIPQFCIPCQLHNTTPVGNVWQPDAIE 1309
            ++   +V V  +D G +E +    +  +L  +  +P   + C L +  P+G  W  +A+ 
Sbjct: 559  KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618

Query: 1310 VLQQLLSKRQVDIHIMELPKNPWEKLSIHLYFDG-MSLSYFMA---YYKYCTSEHTEEML 1365
              ++ +  +++ IHI++   + +    +     G  ++S  +A   Y KY   E  E +L
Sbjct: 619  FFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVIAQAGYAKYQEFETKENIL 678

Query: 1366 KEKPRSDH-DKKYEEEQWEIRF------EELLSAETDTPLLPPYLSSSLPSPGELYAVQV 1418
                   H    +  E  +I F      E+    E  T  +   LS +         + V
Sbjct: 679  VNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVV 738

Query: 1419 KHVVSPNEVYI-----CLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEA 1473
            +  V    VY      CL+ I+  + S    +   +     S  E+      ++ + ++ 
Sbjct: 739  QEKVKRASVYFPLMQNCLE-IKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQG 797

Query: 1474 LPPLTD-------------FRTEMPCLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYG 1519
            L  L                R  + CLA+   +  W RA I  I+    ++  V FVDYG
Sbjct: 798  LKTLMSDIQYYCKNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVN--VTFVDYG 855

Query: 1520 STAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPL 1555
                +++  +  I    ++  A+A +  L     P+
Sbjct: 856  DREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPV 891



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 93/424 (21%), Positives = 163/424 (38%), Gaps = 70/424 (16%)

Query: 1146 KTADI---ISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKL 1202
            KTA +   +SE+K+ +  +K L  +     +   +P        VS + D    +V    
Sbjct: 1268 KTARVEATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKT-TVYVSHINDLSDFYVQLIE 1326

Query: 1203 SEFELIKMTNEIQS-NLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVV-GGAVRVQ 1260
             E E+  ++  + S   +    + P   +    CAV   D LWYR  + E      + VQ
Sbjct: 1327 DEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQ 1386

Query: 1261 YLDHG-----FTEKIPQCHLYPILLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLL 1315
            ++D+G      T KI +  L   +L    P  CI C L       N      +    Q  
Sbjct: 1387 FIDYGNVSVVHTNKIGRLDLVNAIL----PGLCIHCSLQGFEVPDNKNSKKMMHYFSQRT 1442

Query: 1316 SKRQVDIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDK 1375
            S+  +    ++  ++ WE +    +  G+     ++  +Y  SE ++  L  +       
Sbjct: 1443 SEAAIRCEFVKF-QDRWEVILADEH--GIIADDMIS--RYALSEKSQVELSTQVIKSASS 1497

Query: 1376 KYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIE 1435
            K            +  ++ DT +   +L+   P    + A     V+   E + C     
Sbjct: 1498 K-----------SVNKSDIDTSV---FLNWYNPEKKMIRAYAT--VIDGPEYFWC----- 1536

Query: 1436 TSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVE------ALPPLTDFRTEMPCLAE 1489
                  Q +DT+        + + L+  +Q   ++V         P + D     PC+  
Sbjct: 1537 ------QFADTE--------KLQCLEVEVQTAGEQVADRRNCIPCPYIGD-----PCIVR 1577

Query: 1490 Y-DDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAK-LTLNRLCQIPSHLMRYPARAIKVL 1547
            Y +DG +YRA I  I E   +S  V+ VD+G+    +    L  IPS L+  P +A    
Sbjct: 1578 YREDGHYYRALITNICEDYLVS--VRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCC 1635

Query: 1548 LAGF 1551
            L+GF
Sbjct: 1636 LSGF 1639


>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
            sapiens]
          Length = 2080

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 126/624 (20%), Positives = 241/624 (38%), Gaps = 60/624 (9%)

Query: 681  SVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDG 740
            SV V    SP  FY QLI+    L  L      +     +     C      CVA+  +G
Sbjct: 390  SVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449

Query: 741  IWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYK 800
             W+R  +  L    +V++ ++D+G++  I    V+K+K +F+  P  +  C L  +    
Sbjct: 450  QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPD 509

Query: 801  RTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTS------IN 854
            R  +  +     F++    + +   +    +D  L    + +L   E T  S      + 
Sbjct: 510  RDARIFQ--LSIFKQALLGQVVYAHIDWFNKDECL---YYVTLQTQESTVNSKCLLKTVG 564

Query: 855  DQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSL-----PNEN 909
             Q++   ++  +I  IL + S   +  +  + E  + N   +++ ++ K +     P + 
Sbjct: 565  TQVLCP-MSDSKISNILSETSVSDVNSF--AVESFMGNIEWSIDSLNKKGILKVGFPIKT 621

Query: 910  FQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEE------KMIAAYENSKWEPVKW 963
             Q          I  V++P      W+ T +  N  +E      K     EN +    K 
Sbjct: 622  VQMEIEAAYIAFIAYVLNPSNF---WVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKP 678

Query: 964  ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGR 1023
            E  + C  +     ++ R  +I  +    + V   D G    +    ++ L      +  
Sbjct: 679  EPGLFCCARYSKDRRFYRA-VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPA 737

Query: 1024 LSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCR 1083
            L++ CSL  I P    D WT  A D     +      I+LQV +++++  + + ++    
Sbjct: 738  LAMCCSLAHIFPV--EDLWTKAAIDYFKKLVLN--KAILLQVIAKKDD-KYTVNIQSV-- 790

Query: 1084 DEKGERVDVSKYLIKKGLA-------------LRERRINNLDNSHSLS-EKSLEVPLEQE 1129
             E  E +DV   +++ G A             + E  + N ++ + ++ +K +   LE  
Sbjct: 791  -EASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGP 849

Query: 1130 DSV---VTNCIKTNFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEAT 1186
             S      N ++ N    K  A  ISE K + F   +  P ++  YK        V E  
Sbjct: 850  KSKKYHSNNLVENNLSLPKSLAVNISEFK-NPFTLSV-GPESSWPYKEYIFRPGTVLEVK 907

Query: 1187 VSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYR 1246
             SC    G      +    +L  +  +IQ+        +PY  + G+   V      W R
Sbjct: 908  CSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHS--DPY--EIGQTACVAKYSGKWCR 963

Query: 1247 GKVMEVVGGAVRVQYLDHGFTEKI 1270
              V+  V   V + ++D+G+ +++
Sbjct: 964  AAVLTQVSKEVDIVFVDYGYQKRV 987



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 76/357 (21%), Positives = 143/357 (40%), Gaps = 23/357 (6%)

Query: 684  VCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWY 743
            V +I++P +F++QL E   ++  L            E   +   V D        D   Y
Sbjct: 1447 VSNISNPANFHIQLAENESVIIRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNAIY 1506

Query: 744  RAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTM 803
            RA +  +      EV+++D+GN+A +    + +++ EFL  P+  I   L+ ++  +   
Sbjct: 1507 RAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDE 1566

Query: 804  QWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELF--DSLGAPEMTTTSINDQLVKEG 861
             W  +  + F  K  +K + C  +K   D    V +   +     E+       +L K  
Sbjct: 1567 IWDDKTVDYFTSKVHNKTVYCEFLK-KHDQKWEVNMICDEKCVINELLKWKACSKLQKSA 1625

Query: 862  LASYEIGYILKDNSQKHIEVWDPSPEEIISNEVH---NLNPVSAKSLPNENFQSLYNKEL 918
            L   ++       SQK +   D   ++  SNE     N N    K +P E F+    +  
Sbjct: 1626 LQMPQV------LSQK-VRPGDNEMKKGKSNESEGSMNSNQQLFK-IPLEEFK--LGQLE 1675

Query: 919  PVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEPV----KWENDMHCAVKIQ 974
               + NV    + YV+    + +L+ L   ++   +  K  P       E  + C  K +
Sbjct: 1676 KAEMLNVSKSGRFYVKLSKNKKILSDL---IVLITKEEKKSPFLSMESIEKGLECLAKSK 1732

Query: 975  DKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLV 1031
            +  +W R ++     D  V V L D G+  +V V   + L   ++ + R ++ C  +
Sbjct: 1733 NTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKWI 1789



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 134/657 (20%), Positives = 263/657 (40%), Gaps = 89/657 (13%)

Query: 415  SAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGARIFVSS 474
            +A + F+++V++P +F++R      + + + K +N+F +   + D   + +    +F  +
Sbjct: 628  AAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN-DEMILRKPEPGLFCCA 686

Query: 475  --IKNGMWCRGTITELIPIE--------GRNTRKPCSPTRLFVHEVALIQIFMVDFGNSE 524
               K+  + R  ITE+   +        G     P    ++ + E   +    +    + 
Sbjct: 687  RYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAH 746

Query: 525  VLIVTGVVDTHVRPEHSAKQHIALNDLCL---VLRKSEPYTEGLLKDIQPLAQPCSLKDI 581
            +  V    D   +      + + LN   L   + +K + YT     +IQ +    ++ D+
Sbjct: 747  IFPVE---DLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTV----NIQSVEASENI-DV 798

Query: 582  VPQNSNEGWEEEAKVEF---------LKMVNNKAVSMKVFREEDGVLIVDLQKPPPNKIS 632
            +      G+ E  +VE            M+N+++ +    ++   V+   L+ P   K  
Sbjct: 799  ISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKK---VISALLEGPKSKKYH 855

Query: 633  SDMPVSLRDAL---VFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINS 689
            S+  V    +L   + + +++FK+    S   +++  +      P  + +V  +  +   
Sbjct: 856  SNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYY--G 913

Query: 690  PGDFYLQL-IEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVI 748
            PGDF  QL  +  D+  L++ I+ +Y S   +  EI       ACVAK+  G W RA V+
Sbjct: 914  PGDFSCQLQCKSEDLKLLMEQIQNYY-SIHSDPYEI----GQTACVAKYS-GKWCRAAVL 967

Query: 749  GLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKL-AYIEPYK-RTMQWS 806
                 +EV++ +VD+G   ++ I+D+  I   FL    +A +C L  +IEP   +   W+
Sbjct: 968  TQVS-KEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWT 1026

Query: 807  KEAKEKFEE--KAQDKFMTCSV--IKILEDNVL--LVELFDSLGAPEMTTTSINDQLVKE 860
            ++A         +    +TC +  + I+  N L  LV+L  S        TS  + L+  
Sbjct: 1027 RKAFRDLWNFISSSRGLLTCIIYALVIIHPNHLYNLVDLQSSF-------TSAKEFLMNR 1079

Query: 861  GLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPV 920
            G A Y             I + +  P           +  S  S    +F      E  V
Sbjct: 1080 GSAQY-------------ITLSETFP-----------SLFSLYSYCYSSFNIQIGSEEEV 1115

Query: 921  HICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWR 980
            +I ++ SP+K Y Q       L  +E K+  +     +          C  K  +     
Sbjct: 1116 YISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDGLSY 1175

Query: 981  RGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTM---GRLSLECSLVDIR 1034
            R   I   + +  +V   D G + +V  + LR +      +      +++C L D+R
Sbjct: 1176 RALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLR 1232



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 70/344 (20%), Positives = 142/344 (41%), Gaps = 33/344 (9%)

Query: 1235 CAVRGSDTLWYRGKVMEVVGGAVRVQYLDHGFTEKIPQCHLYPIL-LYPDIPQFCIPCQL 1293
            CA    D  +YR  + E+ G  + V +LD+G T+ IP   +  +L  + ++P   + C L
Sbjct: 685  CARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSL 744

Query: 1294 HNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPW----EKLSIHLYFDGMSLSYF 1349
             +  PV ++W   AI+  ++L+  + + + ++    + +    + +      D +SL   
Sbjct: 745  AHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQ 804

Query: 1350 MAYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSS---- 1405
              Y +Y      E     K  S++     E + ++  ++++SA  + P    Y S+    
Sbjct: 805  AGYAEYF---QVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGPKSKKYHSNNLVE 861

Query: 1406 ---SLPSPGELYAVQVKHVVS---------PNEVYICLDSIETSNQSNQHSDTDDSGVSG 1453
               SLP    +   + K+  +         P + YI         + + +    D     
Sbjct: 862  NNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPGDFSCQL 921

Query: 1454 ESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKIV--AIKEFNPLSI 1511
            + +SE L   ++++           +   +  C+A+Y  G W RA ++    KE +    
Sbjct: 922  QCKSEDLKLLMEQIQNYYSIHSDPYEI-GQTACVAKY-SGKWCRAAVLTQVSKEVD---- 975

Query: 1512 LVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPL 1555
             + FVDYG   ++ +  LC I    +   ++A +  L  F  P+
Sbjct: 976  -IVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPV 1018



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 47/168 (27%), Positives = 80/168 (47%), Gaps = 10/168 (5%)

Query: 678  TDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
            ++  V + HI SP  FY QL      L +++T  +  +S + +N       + + C++K+
Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIET--KITESVNLQNFPKYDSNKMRVCISKY 1168

Query: 738  -EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEF---LNAPEKAIKCKL 793
             EDG+ YRA  I      E +V +VDFGN   +    +R I  +F   L  P +AIKC L
Sbjct: 1169 VEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFL 1228

Query: 794  AYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFD 841
            + +    R +    E    F++    + +   ++    D  L +EL+D
Sbjct: 1229 SDL----RDVDIPAEISSWFKDNFLGRSLKAIILSQESDGQLGIELYD 1272



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 103/473 (21%), Positives = 189/473 (39%), Gaps = 53/473 (11%)

Query: 647  ELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILF- 705
            E+ K KS         N  L   P    K        + +++  G FY++L +   IL  
Sbjct: 1642 EMKKGKSNESEGSMNSNQQLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSD 1701

Query: 706  LLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGI-WYRAKVIGLPGHQEVEVKYVDFG 764
            L+  I +  K     ++E +   +   C+AK ++ + W+R+KV       +V V  VD G
Sbjct: 1702 LIVLITKEEKKSPFLSMESI--EKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCG 1759

Query: 765  NTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTC 824
                + + + + + +E  N P +A+ CK  + E  K            FE    D     
Sbjct: 1760 IYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSKNI---------SFECLFAD----- 1805

Query: 825  SVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDP 884
                 LE N+L ++  D++   E+    ++D L+ E L    +  +  + ++  +     
Sbjct: 1806 -----LEINILFLKYLDAVWEVEIL---VDDLLLLEYL---NLNTVPVEENKLRL----- 1849

Query: 885  SPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVIS-PEKIYVQWLLTENLLN 943
               EI+ N + +  PVS+ ++ +  +    N      I   +S P    +Q     +++ 
Sbjct: 1850 --AEIVYN-IESKTPVSSCTIKSFTWVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMK 1906

Query: 944  SLEEKMIAAYENSKWEPVKW-ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGV 1002
             L   +    E  +  P ++      C  K + ++QW R +I  +   +L  VL+ D G 
Sbjct: 1907 YLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEVSPQSLCLVLV-DYGF 1965

Query: 1003 ELVV---NVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVA 1059
               +    +  L+ + E L  + RLS  C L  I PA G   W+  A     ++    ++
Sbjct: 1966 SFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGK-HWSEEA----KIFFRDFLS 2020

Query: 1060 TIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALRERRINNLD 1112
               L     E ++   L V +    EK    D+   L+  GLA   +   +LD
Sbjct: 2021 KPDLVFQFREYHSETKLKVDVI--HEKNNLADI---LVASGLATYSKDSPHLD 2068



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/380 (21%), Positives = 149/380 (39%), Gaps = 72/380 (18%)

Query: 964  ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGR 1023
            E D  C V+ +   +W+RG+++    + L  VLL D G EL V    +     NL  +  
Sbjct: 207  EIDEFCLVEERVSGEWQRGRVMEKKNE-LYTVLLIDRGEELRVAGPQIASACGNLFELPP 265

Query: 1024 LSLECSLVDIRPAGGSDKWTATACD----CLSLYLTGAVATIILQVDSEENNTTWPLPVK 1079
              +     +I P G  +KW+  A +     + + + G V  I+            PL + 
Sbjct: 266  RVVFGIFANILPVG--EKWSPKALNYFKSLVGIQVKGYVQAIL------------PLQMF 311

Query: 1080 IFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKT 1139
            +F         +V K +I + L L+  R+ + D+   + E   E P +  D +     + 
Sbjct: 312  LF---------EVPK-IISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPEL 361

Query: 1140 NFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVV 1199
            +      + DI   Q V +  +  L   +T   K  +  + + F                
Sbjct: 362  SLGNKDTSLDI---QHVLDKLQPSLSVGSTESVKVSSALSPSKFYC-------------- 404

Query: 1200 PKLSEFELIKMTNEIQSNLKCLGL--------LEPYFWKKGEACAVRGSDTLWYRGKVME 1251
                  +LIK T E+++    + L          P     G  C  R  +  W+RG + +
Sbjct: 405  ------QLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNGQWHRGILQQ 458

Query: 1252 VVG-GAVRVQYLDHGFTEKIPQCHLYPILLYPD---IPQFCIPCQ---LHNTTPVGNVWQ 1304
            ++    V++ ++D+G +E IP   +Y   L  D   +P F  PC    LH+      ++Q
Sbjct: 459  LLPPNQVKIWFMDYGSSEAIPS--IYVKKLKQDFILVPLFSFPCSLTCLHSPDRDARIFQ 516

Query: 1305 PDAIEVLQQLLSKRQVDIHI 1324
               + + +Q L  + V  HI
Sbjct: 517  ---LSIFKQALLGQVVYAHI 533



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 72/366 (19%), Positives = 148/366 (40%), Gaps = 35/366 (9%)

Query: 679  DVSVTVCHINSPGDFYLQLIEGL-------DILFLLKTIEEFYKSEDGENLEILCPVQDQ 731
            DV +T+ HI       L   +G+       D   L + I+   K ++   ++  C V+++
Sbjct: 158  DVDLTISHIKCLPKDILVKFQGIKSNECEFDYHVLQREIQHTPKVKNNVEIDEFCLVEER 217

Query: 732  ACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKC 791
                    G W R +V+    ++   V  +D G   ++    +          P + +  
Sbjct: 218  V------SGEWQRGRVMEKK-NELYTVLLIDRGEELRVAGPQIASACGNLFELPPRVVFG 270

Query: 792  KLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTT 851
              A I P     +WS +A   F      K +    +K     +L +++F     P++ + 
Sbjct: 271  IFANILPVGE--KWSPKALNYF------KSLVGIQVKGYVQAILPLQMF-LFEVPKIISQ 321

Query: 852  SINDQLVK--EGLASYEIGYILKDNSQKHIEVWDPS-PEEIISNEVHNLN--PVSAKSLP 906
            ++  QL +  +G +   I  +L++  Q+  ++     PE  + N+  +L+   V  K  P
Sbjct: 322  ALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQP 381

Query: 907  NENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYEN--SKWEPVKWE 964
            + +  S  +    V + + +SP K Y Q +     L +L   M   Y+    +  P    
Sbjct: 382  SLSVGSTES----VKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDN 437

Query: 965  NDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRL 1024
              + C  + ++  QW RG + +++    V++   D G    +    ++KL+++   +   
Sbjct: 438  FGLLCVARRRN-GQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLF 496

Query: 1025 SLECSL 1030
            S  CSL
Sbjct: 497  SFPCSL 502



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 72/332 (21%), Positives = 121/332 (36%), Gaps = 60/332 (18%)

Query: 1244 WYRGKVMEVVGGAVRVQYLDHGFTEKI--PQCHLYPILLYPDIPQFCIPCQLHNTTPVGN 1301
            W RG+VME       V  +D G   ++  PQ       L+ ++P   +     N  PVG 
Sbjct: 222  WQRGRVMEKKNELYTVLLIDRGEELRVAGPQIASACGNLF-ELPPRVVFGIFANILPVGE 280

Query: 1302 VWQPDAIEVLQQLLSKR---------QVDIHIMELPKNPWEKLSIHL--YFDGMSLSYFM 1350
             W P A+   + L+  +          + + + E+PK   + L + L    DG S    +
Sbjct: 281  KWSPKALNYFKSLVGIQVKGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIV 340

Query: 1351 AYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLP-- 1408
                        EML+E P+   D    +        EL     DT L   ++   L   
Sbjct: 341  ------------EMLEEFPQQMPDLLQHKR------PELSLGNKDTSLDIQHVLDKLQPS 382

Query: 1409 -SPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRV 1467
             S G   +V+V   +SP++ Y  L                   +    E E+L   +   
Sbjct: 383  LSVGSTESVKVSSALSPSKFYCQL-------------------IKWTPELENLTAHMTLH 423

Query: 1468 NKKV--EALPPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLT 1525
               V  E  P   +F   + C+A   +G W+R  +  +    P  + + F+DYGS+  + 
Sbjct: 424  YDTVCQETSPTCDNF--GLLCVARRRNGQWHRGILQQL--LPPNQVKIWFMDYGSSEAIP 479

Query: 1526 LNRLCQIPSHLMRYPARAIKVLLAGFKPPLRD 1557
               + ++    +  P  +    L     P RD
Sbjct: 480  SIYVKKLKQDFILVPLFSFPCSLTCLHSPDRD 511



 Score = 38.1 bits (87), Expect = 0.070
 Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 13/149 (8%)

Query: 1409 SPGELYAVQVKHVVSPNEVYICLDS----IETSNQSNQHSDTDDSGVSGESESESLDEAL 1464
            +P +L   Q+K +  P ++Y+           SN +N H    ++       +++L+   
Sbjct: 1420 NPYDLIRPQIKDLPQP-QIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADALNATA 1478

Query: 1465 QRVNKKVEALPPLTDFRTEMPCLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYGSTAK 1523
            +R+ ++    P + D       +AEY  D   YRA I  I   N  S  V+F+DYG++A 
Sbjct: 1479 RRLRERKSVKPLVGDL-----VVAEYSGDNAIYRAVIKKILPGN--SFEVEFIDYGNSAI 1531

Query: 1524 LTLNRLCQIPSHLMRYPARAIKVLLAGFK 1552
            +  +++ ++    +  P   I   L+G K
Sbjct: 1532 VNTSKIYELQREFLTVPQLGIHAFLSGVK 1560



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 7/120 (5%)

Query: 1205 FELIKMTNEIQSNL-KCLGLLEPYFWKKGEACAVR-GSDTLWYRGKVMEVVGGAVRVQYL 1262
            F+++K    + S+L + L  L   F   G +C  +  S+  W R ++ EV   ++ +  +
Sbjct: 1902 FDIMKYLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEVSPQSLCLVLV 1961

Query: 1263 DHGFTEKIPQCHLYPILLYPD----IPQFCIPCQLHNTTPV-GNVWQPDAIEVLQQLLSK 1317
            D+GF+  I    +  + + P+    +P+   PC L+   P  G  W  +A    +  LSK
Sbjct: 1962 DYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEEAKIFFRDFLSK 2021



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 11/60 (18%)

Query: 1486 CLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYGST-------AKLTLNRLCQIPSHLM 1537
            C A Y  D  +YRA    I E N   I V F+DYG+T        K+ L   C++P+  M
Sbjct: 684  CCARYSKDRRFYRA---VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAM 740


>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
            sapiens]
          Length = 2080

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 126/624 (20%), Positives = 241/624 (38%), Gaps = 60/624 (9%)

Query: 681  SVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDG 740
            SV V    SP  FY QLI+    L  L      +     +     C      CVA+  +G
Sbjct: 390  SVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449

Query: 741  IWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYK 800
             W+R  +  L    +V++ ++D+G++  I    V+K+K +F+  P  +  C L  +    
Sbjct: 450  QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPD 509

Query: 801  RTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTS------IN 854
            R  +  +     F++    + +   +    +D  L    + +L   E T  S      + 
Sbjct: 510  RDARIFQ--LSIFKQALLGQVVYAHIDWFNKDECL---YYVTLQTQESTVNSKCLLKTVG 564

Query: 855  DQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSL-----PNEN 909
             Q++   ++  +I  IL + S   +  +  + E  + N   +++ ++ K +     P + 
Sbjct: 565  TQVLCP-MSDSKISNILSETSVSDVNSF--AVESFMGNIEWSIDSLNKKGILKVGFPIKT 621

Query: 910  FQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEE------KMIAAYENSKWEPVKW 963
             Q          I  V++P      W+ T +  N  +E      K     EN +    K 
Sbjct: 622  VQMEIEAAYIAFIAYVLNPSNF---WVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKP 678

Query: 964  ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGR 1023
            E  + C  +     ++ R  +I  +    + V   D G    +    ++ L      +  
Sbjct: 679  EPGLFCCARYSKDRRFYRA-VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPA 737

Query: 1024 LSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCR 1083
            L++ CSL  I P    D WT  A D     +      I+LQV +++++  + + ++    
Sbjct: 738  LAMCCSLAHIFPV--EDLWTKAAIDYFKKLVLN--KAILLQVIAKKDD-KYTVNIQSV-- 790

Query: 1084 DEKGERVDVSKYLIKKGLA-------------LRERRINNLDNSHSLS-EKSLEVPLEQE 1129
             E  E +DV   +++ G A             + E  + N ++ + ++ +K +   LE  
Sbjct: 791  -EASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGP 849

Query: 1130 DSV---VTNCIKTNFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEAT 1186
             S      N ++ N    K  A  ISE K + F   +  P ++  YK        V E  
Sbjct: 850  KSKKYHSNNLVENNLSLPKSLAVNISEFK-NPFTLSV-GPESSWPYKEYIFRPGTVLEVK 907

Query: 1187 VSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYR 1246
             SC    G      +    +L  +  +IQ+        +PY  + G+   V      W R
Sbjct: 908  CSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHS--DPY--EIGQTACVAKYSGKWCR 963

Query: 1247 GKVMEVVGGAVRVQYLDHGFTEKI 1270
              V+  V   V + ++D+G+ +++
Sbjct: 964  AAVLTQVSKEVDIVFVDYGYQKRV 987



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 76/357 (21%), Positives = 143/357 (40%), Gaps = 23/357 (6%)

Query: 684  VCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWY 743
            V +I++P +F++QL E   ++  L            E   +   V D        D   Y
Sbjct: 1447 VSNISNPANFHIQLAENESVIIRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNAIY 1506

Query: 744  RAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTM 803
            RA +  +      EV+++D+GN+A +    + +++ EFL  P+  I   L+ ++  +   
Sbjct: 1507 RAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDE 1566

Query: 804  QWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELF--DSLGAPEMTTTSINDQLVKEG 861
             W  +  + F  K  +K + C  +K   D    V +   +     E+       +L K  
Sbjct: 1567 IWDDKTVDYFTSKVHNKTVYCEFLK-KHDQKWEVNMICDEKCVINELLKWKACSKLQKSA 1625

Query: 862  LASYEIGYILKDNSQKHIEVWDPSPEEIISNEVH---NLNPVSAKSLPNENFQSLYNKEL 918
            L   ++       SQK +   D   ++  SNE     N N    K +P E F+    +  
Sbjct: 1626 LQMPQV------LSQK-VRPGDNEMKKGKSNESEGSMNSNQQLFK-IPLEEFK--LGQLE 1675

Query: 919  PVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEPV----KWENDMHCAVKIQ 974
               + NV    + YV+    + +L+ L   ++   +  K  P       E  + C  K +
Sbjct: 1676 KAEMLNVSKSGRFYVKLSKNKKILSDL---IVLITKEEKKSPFLSMESIEKGLECLAKSK 1732

Query: 975  DKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLV 1031
            +  +W R ++     D  V V L D G+  +V V   + L   ++ + R ++ C  +
Sbjct: 1733 NTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKWI 1789



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 134/657 (20%), Positives = 263/657 (40%), Gaps = 89/657 (13%)

Query: 415  SAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGARIFVSS 474
            +A + F+++V++P +F++R      + + + K +N+F +   + D   + +    +F  +
Sbjct: 628  AAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN-DEMILRKPEPGLFCCA 686

Query: 475  --IKNGMWCRGTITELIPIE--------GRNTRKPCSPTRLFVHEVALIQIFMVDFGNSE 524
               K+  + R  ITE+   +        G     P    ++ + E   +    +    + 
Sbjct: 687  RYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAH 746

Query: 525  VLIVTGVVDTHVRPEHSAKQHIALNDLCL---VLRKSEPYTEGLLKDIQPLAQPCSLKDI 581
            +  V    D   +      + + LN   L   + +K + YT     +IQ +    ++ D+
Sbjct: 747  IFPVE---DLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTV----NIQSVEASENI-DV 798

Query: 582  VPQNSNEGWEEEAKVEF---------LKMVNNKAVSMKVFREEDGVLIVDLQKPPPNKIS 632
            +      G+ E  +VE            M+N+++ +    ++   V+   L+ P   K  
Sbjct: 799  ISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKK---VISALLEGPKSKKYH 855

Query: 633  SDMPVSLRDAL---VFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINS 689
            S+  V    +L   + + +++FK+    S   +++  +      P  + +V  +  +   
Sbjct: 856  SNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYY--G 913

Query: 690  PGDFYLQL-IEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVI 748
            PGDF  QL  +  D+  L++ I+ +Y S   +  EI       ACVAK+  G W RA V+
Sbjct: 914  PGDFSCQLQCKSEDLKLLMEQIQNYY-SIHSDPYEI----GQTACVAKYS-GKWCRAAVL 967

Query: 749  GLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKL-AYIEPYK-RTMQWS 806
                 +EV++ +VD+G   ++ I+D+  I   FL    +A +C L  +IEP   +   W+
Sbjct: 968  TQVS-KEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWT 1026

Query: 807  KEAKEKFEE--KAQDKFMTCSV--IKILEDNVL--LVELFDSLGAPEMTTTSINDQLVKE 860
            ++A         +    +TC +  + I+  N L  LV+L  S        TS  + L+  
Sbjct: 1027 RKAFRDLWNFISSSRGLLTCIIYALVIIHPNHLYNLVDLQSSF-------TSAKEFLMNR 1079

Query: 861  GLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPV 920
            G A Y             I + +  P           +  S  S    +F      E  V
Sbjct: 1080 GSAQY-------------ITLSETFP-----------SLFSLYSYCYSSFNIQIGSEEEV 1115

Query: 921  HICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWR 980
            +I ++ SP+K Y Q       L  +E K+  +     +          C  K  +     
Sbjct: 1116 YISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDGLSY 1175

Query: 981  RGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTM---GRLSLECSLVDIR 1034
            R   I   + +  +V   D G + +V  + LR +      +      +++C L D+R
Sbjct: 1176 RALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLR 1232



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 70/344 (20%), Positives = 142/344 (41%), Gaps = 33/344 (9%)

Query: 1235 CAVRGSDTLWYRGKVMEVVGGAVRVQYLDHGFTEKIPQCHLYPIL-LYPDIPQFCIPCQL 1293
            CA    D  +YR  + E+ G  + V +LD+G T+ IP   +  +L  + ++P   + C L
Sbjct: 685  CARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSL 744

Query: 1294 HNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPW----EKLSIHLYFDGMSLSYF 1349
             +  PV ++W   AI+  ++L+  + + + ++    + +    + +      D +SL   
Sbjct: 745  AHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQ 804

Query: 1350 MAYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSS---- 1405
              Y +Y      E     K  S++     E + ++  ++++SA  + P    Y S+    
Sbjct: 805  AGYAEYF---QVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGPKSKKYHSNNLVE 861

Query: 1406 ---SLPSPGELYAVQVKHVVS---------PNEVYICLDSIETSNQSNQHSDTDDSGVSG 1453
               SLP    +   + K+  +         P + YI         + + +    D     
Sbjct: 862  NNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPGDFSCQL 921

Query: 1454 ESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKIV--AIKEFNPLSI 1511
            + +SE L   ++++           +   +  C+A+Y  G W RA ++    KE +    
Sbjct: 922  QCKSEDLKLLMEQIQNYYSIHSDPYEI-GQTACVAKY-SGKWCRAAVLTQVSKEVD---- 975

Query: 1512 LVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPL 1555
             + FVDYG   ++ +  LC I    +   ++A +  L  F  P+
Sbjct: 976  -IVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPV 1018



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 47/168 (27%), Positives = 80/168 (47%), Gaps = 10/168 (5%)

Query: 678  TDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
            ++  V + HI SP  FY QL      L +++T  +  +S + +N       + + C++K+
Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIET--KITESVNLQNFPKYDSNKMRVCISKY 1168

Query: 738  -EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEF---LNAPEKAIKCKL 793
             EDG+ YRA  I      E +V +VDFGN   +    +R I  +F   L  P +AIKC L
Sbjct: 1169 VEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFL 1228

Query: 794  AYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFD 841
            + +    R +    E    F++    + +   ++    D  L +EL+D
Sbjct: 1229 SDL----RDVDIPAEISSWFKDNFLGRSLKAIILSQESDGQLGIELYD 1272



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 103/473 (21%), Positives = 189/473 (39%), Gaps = 53/473 (11%)

Query: 647  ELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILF- 705
            E+ K KS         N  L   P    K        + +++  G FY++L +   IL  
Sbjct: 1642 EMKKGKSNESEGSMNSNQQLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSD 1701

Query: 706  LLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGI-WYRAKVIGLPGHQEVEVKYVDFG 764
            L+  I +  K     ++E +   +   C+AK ++ + W+R+KV       +V V  VD G
Sbjct: 1702 LIVLITKEEKKSPFLSMESI--EKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCG 1759

Query: 765  NTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTC 824
                + + + + + +E  N P +A+ CK  + E  K            FE    D     
Sbjct: 1760 IYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSKNI---------SFECLFAD----- 1805

Query: 825  SVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDP 884
                 LE N+L ++  D++   E+    ++D L+ E L    +  +  + ++  +     
Sbjct: 1806 -----LEINILFLKYLDAVWEVEIL---VDDLLLLEYL---NLNTVPVEENKLRL----- 1849

Query: 885  SPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVIS-PEKIYVQWLLTENLLN 943
               EI+ N + +  PVS+ ++ +  +    N      I   +S P    +Q     +++ 
Sbjct: 1850 --AEIVYN-IESKTPVSSCTIKSFTWVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMK 1906

Query: 944  SLEEKMIAAYENSKWEPVKW-ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGV 1002
             L   +    E  +  P ++      C  K + ++QW R +I  +   +L  VL+ D G 
Sbjct: 1907 YLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEVSPQSLCLVLV-DYGF 1965

Query: 1003 ELVV---NVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVA 1059
               +    +  L+ + E L  + RLS  C L  I PA G   W+  A     ++    ++
Sbjct: 1966 SFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGK-HWSEEA----KIFFRDFLS 2020

Query: 1060 TIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALRERRINNLD 1112
               L     E ++   L V +    EK    D+   L+  GLA   +   +LD
Sbjct: 2021 KPDLVFQFREYHSETKLKVDVI--HEKNNLADI---LVASGLATYSKDSPHLD 2068



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/380 (21%), Positives = 149/380 (39%), Gaps = 72/380 (18%)

Query: 964  ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGR 1023
            E D  C V+ +   +W+RG+++    + L  VLL D G EL V    +     NL  +  
Sbjct: 207  EIDEFCLVEERVSGEWQRGRVMEKKNE-LYTVLLIDRGEELRVAGPQIASACGNLFELPP 265

Query: 1024 LSLECSLVDIRPAGGSDKWTATACD----CLSLYLTGAVATIILQVDSEENNTTWPLPVK 1079
              +     +I P G  +KW+  A +     + + + G V  I+            PL + 
Sbjct: 266  RVVFGIFANILPVG--EKWSPKALNYFKSLVGIQVKGYVQAIL------------PLQMF 311

Query: 1080 IFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKT 1139
            +F         +V K +I + L L+  R+ + D+   + E   E P +  D +     + 
Sbjct: 312  LF---------EVPK-IISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPEL 361

Query: 1140 NFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVV 1199
            +      + DI   Q V +  +  L   +T   K  +  + + F                
Sbjct: 362  SLGNKDTSLDI---QHVLDKLQPSLSVGSTESVKVSSALSPSKFYC-------------- 404

Query: 1200 PKLSEFELIKMTNEIQSNLKCLGL--------LEPYFWKKGEACAVRGSDTLWYRGKVME 1251
                  +LIK T E+++    + L          P     G  C  R  +  W+RG + +
Sbjct: 405  ------QLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNGQWHRGILQQ 458

Query: 1252 VVG-GAVRVQYLDHGFTEKIPQCHLYPILLYPD---IPQFCIPCQ---LHNTTPVGNVWQ 1304
            ++    V++ ++D+G +E IP   +Y   L  D   +P F  PC    LH+      ++Q
Sbjct: 459  LLPPNQVKIWFMDYGSSEAIPS--IYVKKLKQDFILVPLFSFPCSLTCLHSPDRDARIFQ 516

Query: 1305 PDAIEVLQQLLSKRQVDIHI 1324
               + + +Q L  + V  HI
Sbjct: 517  ---LSIFKQALLGQVVYAHI 533



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 72/366 (19%), Positives = 148/366 (40%), Gaps = 35/366 (9%)

Query: 679  DVSVTVCHINSPGDFYLQLIEGL-------DILFLLKTIEEFYKSEDGENLEILCPVQDQ 731
            DV +T+ HI       L   +G+       D   L + I+   K ++   ++  C V+++
Sbjct: 158  DVDLTISHIKCLPKDILVKFQGIKSNECEFDYHVLQREIQHTPKVKNNVEIDEFCLVEER 217

Query: 732  ACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKC 791
                    G W R +V+    ++   V  +D G   ++    +          P + +  
Sbjct: 218  V------SGEWQRGRVMEKK-NELYTVLLIDRGEELRVAGPQIASACGNLFELPPRVVFG 270

Query: 792  KLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTT 851
              A I P     +WS +A   F      K +    +K     +L +++F     P++ + 
Sbjct: 271  IFANILPVGE--KWSPKALNYF------KSLVGIQVKGYVQAILPLQMF-LFEVPKIISQ 321

Query: 852  SINDQLVK--EGLASYEIGYILKDNSQKHIEVWDPS-PEEIISNEVHNLN--PVSAKSLP 906
            ++  QL +  +G +   I  +L++  Q+  ++     PE  + N+  +L+   V  K  P
Sbjct: 322  ALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQP 381

Query: 907  NENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYEN--SKWEPVKWE 964
            + +  S  +    V + + +SP K Y Q +     L +L   M   Y+    +  P    
Sbjct: 382  SLSVGSTES----VKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDN 437

Query: 965  NDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRL 1024
              + C  + ++  QW RG + +++    V++   D G    +    ++KL+++   +   
Sbjct: 438  FGLLCVARRRN-GQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLF 496

Query: 1025 SLECSL 1030
            S  CSL
Sbjct: 497  SFPCSL 502



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 72/332 (21%), Positives = 121/332 (36%), Gaps = 60/332 (18%)

Query: 1244 WYRGKVMEVVGGAVRVQYLDHGFTEKI--PQCHLYPILLYPDIPQFCIPCQLHNTTPVGN 1301
            W RG+VME       V  +D G   ++  PQ       L+ ++P   +     N  PVG 
Sbjct: 222  WQRGRVMEKKNELYTVLLIDRGEELRVAGPQIASACGNLF-ELPPRVVFGIFANILPVGE 280

Query: 1302 VWQPDAIEVLQQLLSKR---------QVDIHIMELPKNPWEKLSIHL--YFDGMSLSYFM 1350
             W P A+   + L+  +          + + + E+PK   + L + L    DG S    +
Sbjct: 281  KWSPKALNYFKSLVGIQVKGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIV 340

Query: 1351 AYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLP-- 1408
                        EML+E P+   D    +        EL     DT L   ++   L   
Sbjct: 341  ------------EMLEEFPQQMPDLLQHKR------PELSLGNKDTSLDIQHVLDKLQPS 382

Query: 1409 -SPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRV 1467
             S G   +V+V   +SP++ Y  L                   +    E E+L   +   
Sbjct: 383  LSVGSTESVKVSSALSPSKFYCQL-------------------IKWTPELENLTAHMTLH 423

Query: 1468 NKKV--EALPPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLT 1525
               V  E  P   +F   + C+A   +G W+R  +  +    P  + + F+DYGS+  + 
Sbjct: 424  YDTVCQETSPTCDNF--GLLCVARRRNGQWHRGILQQL--LPPNQVKIWFMDYGSSEAIP 479

Query: 1526 LNRLCQIPSHLMRYPARAIKVLLAGFKPPLRD 1557
               + ++    +  P  +    L     P RD
Sbjct: 480  SIYVKKLKQDFILVPLFSFPCSLTCLHSPDRD 511



 Score = 38.1 bits (87), Expect = 0.070
 Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 13/149 (8%)

Query: 1409 SPGELYAVQVKHVVSPNEVYICLDS----IETSNQSNQHSDTDDSGVSGESESESLDEAL 1464
            +P +L   Q+K +  P ++Y+           SN +N H    ++       +++L+   
Sbjct: 1420 NPYDLIRPQIKDLPQP-QIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADALNATA 1478

Query: 1465 QRVNKKVEALPPLTDFRTEMPCLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYGSTAK 1523
            +R+ ++    P + D       +AEY  D   YRA I  I   N  S  V+F+DYG++A 
Sbjct: 1479 RRLRERKSVKPLVGDL-----VVAEYSGDNAIYRAVIKKILPGN--SFEVEFIDYGNSAI 1531

Query: 1524 LTLNRLCQIPSHLMRYPARAIKVLLAGFK 1552
            +  +++ ++    +  P   I   L+G K
Sbjct: 1532 VNTSKIYELQREFLTVPQLGIHAFLSGVK 1560



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 7/120 (5%)

Query: 1205 FELIKMTNEIQSNL-KCLGLLEPYFWKKGEACAVR-GSDTLWYRGKVMEVVGGAVRVQYL 1262
            F+++K    + S+L + L  L   F   G +C  +  S+  W R ++ EV   ++ +  +
Sbjct: 1902 FDIMKYLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEVSPQSLCLVLV 1961

Query: 1263 DHGFTEKIPQCHLYPILLYPD----IPQFCIPCQLHNTTPV-GNVWQPDAIEVLQQLLSK 1317
            D+GF+  I    +  + + P+    +P+   PC L+   P  G  W  +A    +  LSK
Sbjct: 1962 DYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEEAKIFFRDFLSK 2021



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 11/60 (18%)

Query: 1486 CLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYGST-------AKLTLNRLCQIPSHLM 1537
            C A Y  D  +YRA    I E N   I V F+DYG+T        K+ L   C++P+  M
Sbjct: 684  CCARYSKDRRFYRA---VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAM 740


>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
            sapiens]
          Length = 2080

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 126/624 (20%), Positives = 241/624 (38%), Gaps = 60/624 (9%)

Query: 681  SVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDG 740
            SV V    SP  FY QLI+    L  L      +     +     C      CVA+  +G
Sbjct: 390  SVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449

Query: 741  IWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYK 800
             W+R  +  L    +V++ ++D+G++  I    V+K+K +F+  P  +  C L  +    
Sbjct: 450  QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPD 509

Query: 801  RTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTS------IN 854
            R  +  +     F++    + +   +    +D  L    + +L   E T  S      + 
Sbjct: 510  RDARIFQ--LSIFKQALLGQVVYAHIDWFNKDECL---YYVTLQTQESTVNSKCLLKTVG 564

Query: 855  DQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSL-----PNEN 909
             Q++   ++  +I  IL + S   +  +  + E  + N   +++ ++ K +     P + 
Sbjct: 565  TQVLCP-MSDSKISNILSETSVSDVNSF--AVESFMGNIEWSIDSLNKKGILKVGFPIKT 621

Query: 910  FQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEE------KMIAAYENSKWEPVKW 963
             Q          I  V++P      W+ T +  N  +E      K     EN +    K 
Sbjct: 622  VQMEIEAAYIAFIAYVLNPSNF---WVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKP 678

Query: 964  ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGR 1023
            E  + C  +     ++ R  +I  +    + V   D G    +    ++ L      +  
Sbjct: 679  EPGLFCCARYSKDRRFYRA-VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPA 737

Query: 1024 LSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCR 1083
            L++ CSL  I P    D WT  A D     +      I+LQV +++++  + + ++    
Sbjct: 738  LAMCCSLAHIFPV--EDLWTKAAIDYFKKLVLN--KAILLQVIAKKDD-KYTVNIQSV-- 790

Query: 1084 DEKGERVDVSKYLIKKGLA-------------LRERRINNLDNSHSLS-EKSLEVPLEQE 1129
             E  E +DV   +++ G A             + E  + N ++ + ++ +K +   LE  
Sbjct: 791  -EASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGP 849

Query: 1130 DSV---VTNCIKTNFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEAT 1186
             S      N ++ N    K  A  ISE K + F   +  P ++  YK        V E  
Sbjct: 850  KSKKYHSNNLVENNLSLPKSLAVNISEFK-NPFTLSV-GPESSWPYKEYIFRPGTVLEVK 907

Query: 1187 VSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYR 1246
             SC    G      +    +L  +  +IQ+        +PY  + G+   V      W R
Sbjct: 908  CSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHS--DPY--EIGQTACVAKYSGKWCR 963

Query: 1247 GKVMEVVGGAVRVQYLDHGFTEKI 1270
              V+  V   V + ++D+G+ +++
Sbjct: 964  AAVLTQVSKEVDIVFVDYGYQKRV 987



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 76/357 (21%), Positives = 143/357 (40%), Gaps = 23/357 (6%)

Query: 684  VCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWY 743
            V +I++P +F++QL E   ++  L            E   +   V D        D   Y
Sbjct: 1447 VSNISNPANFHIQLAENESVIIRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNAIY 1506

Query: 744  RAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTM 803
            RA +  +      EV+++D+GN+A +    + +++ EFL  P+  I   L+ ++  +   
Sbjct: 1507 RAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDE 1566

Query: 804  QWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELF--DSLGAPEMTTTSINDQLVKEG 861
             W  +  + F  K  +K + C  +K   D    V +   +     E+       +L K  
Sbjct: 1567 IWDDKTVDYFTSKVHNKTVYCEFLK-KHDQKWEVNMICDEKCVINELLKWKACSKLQKSA 1625

Query: 862  LASYEIGYILKDNSQKHIEVWDPSPEEIISNEVH---NLNPVSAKSLPNENFQSLYNKEL 918
            L   ++       SQK +   D   ++  SNE     N N    K +P E F+    +  
Sbjct: 1626 LQMPQV------LSQK-VRPGDNEMKKGKSNESEGSMNSNQQLFK-IPLEEFK--LGQLE 1675

Query: 919  PVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEPV----KWENDMHCAVKIQ 974
               + NV    + YV+    + +L+ L   ++   +  K  P       E  + C  K +
Sbjct: 1676 KAEMLNVSKSGRFYVKLSKNKKILSDL---IVLITKEEKKSPFLSMESIEKGLECLAKSK 1732

Query: 975  DKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLV 1031
            +  +W R ++     D  V V L D G+  +V V   + L   ++ + R ++ C  +
Sbjct: 1733 NTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKWI 1789



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 134/657 (20%), Positives = 263/657 (40%), Gaps = 89/657 (13%)

Query: 415  SAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGARIFVSS 474
            +A + F+++V++P +F++R      + + + K +N+F +   + D   + +    +F  +
Sbjct: 628  AAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN-DEMILRKPEPGLFCCA 686

Query: 475  --IKNGMWCRGTITELIPIE--------GRNTRKPCSPTRLFVHEVALIQIFMVDFGNSE 524
               K+  + R  ITE+   +        G     P    ++ + E   +    +    + 
Sbjct: 687  RYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAH 746

Query: 525  VLIVTGVVDTHVRPEHSAKQHIALNDLCL---VLRKSEPYTEGLLKDIQPLAQPCSLKDI 581
            +  V    D   +      + + LN   L   + +K + YT     +IQ +    ++ D+
Sbjct: 747  IFPVE---DLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTV----NIQSVEASENI-DV 798

Query: 582  VPQNSNEGWEEEAKVEF---------LKMVNNKAVSMKVFREEDGVLIVDLQKPPPNKIS 632
            +      G+ E  +VE            M+N+++ +    ++   V+   L+ P   K  
Sbjct: 799  ISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKK---VISALLEGPKSKKYH 855

Query: 633  SDMPVSLRDAL---VFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINS 689
            S+  V    +L   + + +++FK+    S   +++  +      P  + +V  +  +   
Sbjct: 856  SNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYY--G 913

Query: 690  PGDFYLQL-IEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVI 748
            PGDF  QL  +  D+  L++ I+ +Y S   +  EI       ACVAK+  G W RA V+
Sbjct: 914  PGDFSCQLQCKSEDLKLLMEQIQNYY-SIHSDPYEI----GQTACVAKYS-GKWCRAAVL 967

Query: 749  GLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKL-AYIEPYK-RTMQWS 806
                 +EV++ +VD+G   ++ I+D+  I   FL    +A +C L  +IEP   +   W+
Sbjct: 968  TQVS-KEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWT 1026

Query: 807  KEAKEKFEE--KAQDKFMTCSV--IKILEDNVL--LVELFDSLGAPEMTTTSINDQLVKE 860
            ++A         +    +TC +  + I+  N L  LV+L  S        TS  + L+  
Sbjct: 1027 RKAFRDLWNFISSSRGLLTCIIYALVIIHPNHLYNLVDLQSSF-------TSAKEFLMNR 1079

Query: 861  GLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPV 920
            G A Y             I + +  P           +  S  S    +F      E  V
Sbjct: 1080 GSAQY-------------ITLSETFP-----------SLFSLYSYCYSSFNIQIGSEEEV 1115

Query: 921  HICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWR 980
            +I ++ SP+K Y Q       L  +E K+  +     +          C  K  +     
Sbjct: 1116 YISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDGLSY 1175

Query: 981  RGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTM---GRLSLECSLVDIR 1034
            R   I   + +  +V   D G + +V  + LR +      +      +++C L D+R
Sbjct: 1176 RALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLR 1232



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 70/344 (20%), Positives = 142/344 (41%), Gaps = 33/344 (9%)

Query: 1235 CAVRGSDTLWYRGKVMEVVGGAVRVQYLDHGFTEKIPQCHLYPIL-LYPDIPQFCIPCQL 1293
            CA    D  +YR  + E+ G  + V +LD+G T+ IP   +  +L  + ++P   + C L
Sbjct: 685  CARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSL 744

Query: 1294 HNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPW----EKLSIHLYFDGMSLSYF 1349
             +  PV ++W   AI+  ++L+  + + + ++    + +    + +      D +SL   
Sbjct: 745  AHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQ 804

Query: 1350 MAYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSS---- 1405
              Y +Y      E     K  S++     E + ++  ++++SA  + P    Y S+    
Sbjct: 805  AGYAEYF---QVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGPKSKKYHSNNLVE 861

Query: 1406 ---SLPSPGELYAVQVKHVVS---------PNEVYICLDSIETSNQSNQHSDTDDSGVSG 1453
               SLP    +   + K+  +         P + YI         + + +    D     
Sbjct: 862  NNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPGDFSCQL 921

Query: 1454 ESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKIV--AIKEFNPLSI 1511
            + +SE L   ++++           +   +  C+A+Y  G W RA ++    KE +    
Sbjct: 922  QCKSEDLKLLMEQIQNYYSIHSDPYEI-GQTACVAKY-SGKWCRAAVLTQVSKEVD---- 975

Query: 1512 LVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPL 1555
             + FVDYG   ++ +  LC I    +   ++A +  L  F  P+
Sbjct: 976  -IVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPV 1018



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 47/168 (27%), Positives = 80/168 (47%), Gaps = 10/168 (5%)

Query: 678  TDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
            ++  V + HI SP  FY QL      L +++T  +  +S + +N       + + C++K+
Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIET--KITESVNLQNFPKYDSNKMRVCISKY 1168

Query: 738  -EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEF---LNAPEKAIKCKL 793
             EDG+ YRA  I      E +V +VDFGN   +    +R I  +F   L  P +AIKC L
Sbjct: 1169 VEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFL 1228

Query: 794  AYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFD 841
            + +    R +    E    F++    + +   ++    D  L +EL+D
Sbjct: 1229 SDL----RDVDIPAEISSWFKDNFLGRSLKAIILSQESDGQLGIELYD 1272



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 103/473 (21%), Positives = 189/473 (39%), Gaps = 53/473 (11%)

Query: 647  ELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILF- 705
            E+ K KS         N  L   P    K        + +++  G FY++L +   IL  
Sbjct: 1642 EMKKGKSNESEGSMNSNQQLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSD 1701

Query: 706  LLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGI-WYRAKVIGLPGHQEVEVKYVDFG 764
            L+  I +  K     ++E +   +   C+AK ++ + W+R+KV       +V V  VD G
Sbjct: 1702 LIVLITKEEKKSPFLSMESI--EKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCG 1759

Query: 765  NTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTC 824
                + + + + + +E  N P +A+ CK  + E  K            FE    D     
Sbjct: 1760 IYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSKNI---------SFECLFAD----- 1805

Query: 825  SVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDP 884
                 LE N+L ++  D++   E+    ++D L+ E L    +  +  + ++  +     
Sbjct: 1806 -----LEINILFLKYLDAVWEVEIL---VDDLLLLEYL---NLNTVPVEENKLRL----- 1849

Query: 885  SPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVIS-PEKIYVQWLLTENLLN 943
               EI+ N + +  PVS+ ++ +  +    N      I   +S P    +Q     +++ 
Sbjct: 1850 --AEIVYN-IESKTPVSSCTIKSFTWVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMK 1906

Query: 944  SLEEKMIAAYENSKWEPVKW-ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGV 1002
             L   +    E  +  P ++      C  K + ++QW R +I  +   +L  VL+ D G 
Sbjct: 1907 YLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEVSPQSLCLVLV-DYGF 1965

Query: 1003 ELVV---NVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVA 1059
               +    +  L+ + E L  + RLS  C L  I PA G   W+  A     ++    ++
Sbjct: 1966 SFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGK-HWSEEA----KIFFRDFLS 2020

Query: 1060 TIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALRERRINNLD 1112
               L     E ++   L V +    EK    D+   L+  GLA   +   +LD
Sbjct: 2021 KPDLVFQFREYHSETKLKVDVI--HEKNNLADI---LVASGLATYSKDSPHLD 2068



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/380 (21%), Positives = 149/380 (39%), Gaps = 72/380 (18%)

Query: 964  ENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGR 1023
            E D  C V+ +   +W+RG+++    + L  VLL D G EL V    +     NL  +  
Sbjct: 207  EIDEFCLVEERVSGEWQRGRVMEKKNE-LYTVLLIDRGEELRVAGPQIASACGNLFELPP 265

Query: 1024 LSLECSLVDIRPAGGSDKWTATACD----CLSLYLTGAVATIILQVDSEENNTTWPLPVK 1079
              +     +I P G  +KW+  A +     + + + G V  I+            PL + 
Sbjct: 266  RVVFGIFANILPVG--EKWSPKALNYFKSLVGIQVKGYVQAIL------------PLQMF 311

Query: 1080 IFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKT 1139
            +F         +V K +I + L L+  R+ + D+   + E   E P +  D +     + 
Sbjct: 312  LF---------EVPK-IISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPEL 361

Query: 1140 NFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVV 1199
            +      + DI   Q V +  +  L   +T   K  +  + + F                
Sbjct: 362  SLGNKDTSLDI---QHVLDKLQPSLSVGSTESVKVSSALSPSKFYC-------------- 404

Query: 1200 PKLSEFELIKMTNEIQSNLKCLGL--------LEPYFWKKGEACAVRGSDTLWYRGKVME 1251
                  +LIK T E+++    + L          P     G  C  R  +  W+RG + +
Sbjct: 405  ------QLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNGQWHRGILQQ 458

Query: 1252 VVG-GAVRVQYLDHGFTEKIPQCHLYPILLYPD---IPQFCIPCQ---LHNTTPVGNVWQ 1304
            ++    V++ ++D+G +E IP   +Y   L  D   +P F  PC    LH+      ++Q
Sbjct: 459  LLPPNQVKIWFMDYGSSEAIPS--IYVKKLKQDFILVPLFSFPCSLTCLHSPDRDARIFQ 516

Query: 1305 PDAIEVLQQLLSKRQVDIHI 1324
               + + +Q L  + V  HI
Sbjct: 517  ---LSIFKQALLGQVVYAHI 533



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 72/366 (19%), Positives = 148/366 (40%), Gaps = 35/366 (9%)

Query: 679  DVSVTVCHINSPGDFYLQLIEGL-------DILFLLKTIEEFYKSEDGENLEILCPVQDQ 731
            DV +T+ HI       L   +G+       D   L + I+   K ++   ++  C V+++
Sbjct: 158  DVDLTISHIKCLPKDILVKFQGIKSNECEFDYHVLQREIQHTPKVKNNVEIDEFCLVEER 217

Query: 732  ACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKC 791
                    G W R +V+    ++   V  +D G   ++    +          P + +  
Sbjct: 218  V------SGEWQRGRVMEKK-NELYTVLLIDRGEELRVAGPQIASACGNLFELPPRVVFG 270

Query: 792  KLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTT 851
              A I P     +WS +A   F      K +    +K     +L +++F     P++ + 
Sbjct: 271  IFANILPVGE--KWSPKALNYF------KSLVGIQVKGYVQAILPLQMF-LFEVPKIISQ 321

Query: 852  SINDQLVK--EGLASYEIGYILKDNSQKHIEVWDPS-PEEIISNEVHNLN--PVSAKSLP 906
            ++  QL +  +G +   I  +L++  Q+  ++     PE  + N+  +L+   V  K  P
Sbjct: 322  ALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQP 381

Query: 907  NENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYEN--SKWEPVKWE 964
            + +  S  +    V + + +SP K Y Q +     L +L   M   Y+    +  P    
Sbjct: 382  SLSVGSTES----VKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDN 437

Query: 965  NDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRL 1024
              + C  + ++  QW RG + +++    V++   D G    +    ++KL+++   +   
Sbjct: 438  FGLLCVARRRN-GQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLF 496

Query: 1025 SLECSL 1030
            S  CSL
Sbjct: 497  SFPCSL 502



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 72/332 (21%), Positives = 121/332 (36%), Gaps = 60/332 (18%)

Query: 1244 WYRGKVMEVVGGAVRVQYLDHGFTEKI--PQCHLYPILLYPDIPQFCIPCQLHNTTPVGN 1301
            W RG+VME       V  +D G   ++  PQ       L+ ++P   +     N  PVG 
Sbjct: 222  WQRGRVMEKKNELYTVLLIDRGEELRVAGPQIASACGNLF-ELPPRVVFGIFANILPVGE 280

Query: 1302 VWQPDAIEVLQQLLSKR---------QVDIHIMELPKNPWEKLSIHL--YFDGMSLSYFM 1350
             W P A+   + L+  +          + + + E+PK   + L + L    DG S    +
Sbjct: 281  KWSPKALNYFKSLVGIQVKGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIV 340

Query: 1351 AYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLP-- 1408
                        EML+E P+   D    +        EL     DT L   ++   L   
Sbjct: 341  ------------EMLEEFPQQMPDLLQHKR------PELSLGNKDTSLDIQHVLDKLQPS 382

Query: 1409 -SPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRV 1467
             S G   +V+V   +SP++ Y  L                   +    E E+L   +   
Sbjct: 383  LSVGSTESVKVSSALSPSKFYCQL-------------------IKWTPELENLTAHMTLH 423

Query: 1468 NKKV--EALPPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLT 1525
               V  E  P   +F   + C+A   +G W+R  +  +    P  + + F+DYGS+  + 
Sbjct: 424  YDTVCQETSPTCDNF--GLLCVARRRNGQWHRGILQQL--LPPNQVKIWFMDYGSSEAIP 479

Query: 1526 LNRLCQIPSHLMRYPARAIKVLLAGFKPPLRD 1557
               + ++    +  P  +    L     P RD
Sbjct: 480  SIYVKKLKQDFILVPLFSFPCSLTCLHSPDRD 511



 Score = 38.1 bits (87), Expect = 0.070
 Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 13/149 (8%)

Query: 1409 SPGELYAVQVKHVVSPNEVYICLDS----IETSNQSNQHSDTDDSGVSGESESESLDEAL 1464
            +P +L   Q+K +  P ++Y+           SN +N H    ++       +++L+   
Sbjct: 1420 NPYDLIRPQIKDLPQP-QIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADALNATA 1478

Query: 1465 QRVNKKVEALPPLTDFRTEMPCLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYGSTAK 1523
            +R+ ++    P + D       +AEY  D   YRA I  I   N  S  V+F+DYG++A 
Sbjct: 1479 RRLRERKSVKPLVGDL-----VVAEYSGDNAIYRAVIKKILPGN--SFEVEFIDYGNSAI 1531

Query: 1524 LTLNRLCQIPSHLMRYPARAIKVLLAGFK 1552
            +  +++ ++    +  P   I   L+G K
Sbjct: 1532 VNTSKIYELQREFLTVPQLGIHAFLSGVK 1560



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 7/120 (5%)

Query: 1205 FELIKMTNEIQSNL-KCLGLLEPYFWKKGEACAVR-GSDTLWYRGKVMEVVGGAVRVQYL 1262
            F+++K    + S+L + L  L   F   G +C  +  S+  W R ++ EV   ++ +  +
Sbjct: 1902 FDIMKYLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEVSPQSLCLVLV 1961

Query: 1263 DHGFTEKIPQCHLYPILLYPD----IPQFCIPCQLHNTTPV-GNVWQPDAIEVLQQLLSK 1317
            D+GF+  I    +  + + P+    +P+   PC L+   P  G  W  +A    +  LSK
Sbjct: 1962 DYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEEAKIFFRDFLSK 2021



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 11/60 (18%)

Query: 1486 CLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYGST-------AKLTLNRLCQIPSHLM 1537
            C A Y  D  +YRA    I E N   I V F+DYG+T        K+ L   C++P+  M
Sbjct: 684  CCARYSKDRRFYRA---VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAM 740


>gi|112293287 tudor domain containing 7 [Homo sapiens]
          Length = 1098

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 102/465 (21%), Positives = 189/465 (40%), Gaps = 73/465 (15%)

Query: 681  SVTVCHINSPGDFYLQL-IEGLDILF-LLKTIEEFYKSED-GENLEILCPVQDQACVAKF 737
            +V V +I S G  Y Q+  +GL+ L  LL+ IE+++  +       +  P   + C+   
Sbjct: 655  NVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHC 714

Query: 738  EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNA----PEKAIKCKL 793
            + G W R ++  +   + ++V+++D G    + + ++R+I   FL      P +AIKC L
Sbjct: 715  K-GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCL 773

Query: 794  AYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCS-----VIKILEDN-VLLVELFDSLGAPE 847
            A +   +    W+ +A        +D  + CS     V K+ E   +  V LF     P+
Sbjct: 774  ADLP--QSIGMWTPDAVLWL----RDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPD 827

Query: 848  MTTTSINDQLVKEGLASYEIGYILK-----------------------DNSQKHIEVWDP 884
                SIN Q+    L  ++    L                        +N +K++     
Sbjct: 828  -PHRSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLT---- 882

Query: 885  SPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNS 944
              + I  + V + +  S + LP     S   + + V++     P    +Q     + L  
Sbjct: 883  --DVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEV 940

Query: 945  LEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVEL 1004
            L E+MI  Y  S+   +  E D   A K++  N+W R  +  ++T+ LV V   D G   
Sbjct: 941  LMEEMILYYSVSEERHIAVEKDQVYAAKVE--NKWHRVLLKGILTNGLVSVYELDYGKHE 998

Query: 1005 VVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLY-----LTGAVA 1059
            +VN+  ++ L +  + +   ++   L  ++     ++W+  A      +     L   V 
Sbjct: 999  LVNIRKVQPLVDMFRKLPFQAVTAQLAGVK----CNQWSEEASMVFRNHVEKKPLVALVQ 1054

Query: 1060 TIILQVDSEENNTTWPLPVKIFCRDEKGERVD------VSKYLIK 1098
            T+I      EN   W   V ++  D      D      +S+YLI+
Sbjct: 1055 TVI------ENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIE 1093



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 67/269 (24%), Positives = 123/269 (45%), Gaps = 26/269 (9%)

Query: 600  KMVNNKAVSMKVFREEDGVLIVDLQK--PPPNKISSDMPVSLRDALVFME-LAKFKSQSL 656
            + +N +  +  +++ +  V +  +      PN  + +MP+S      F + L     +S+
Sbjct: 830  RSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSM 889

Query: 657  RSHFEKNTTLHYHPPI---LPKEMTDVSVTV-CHINSPGDFYLQLIEGLDIL-FLLKTIE 711
              H    +T    PP+    P E  DV V V CH   PG F +Q  + +  L  L++ + 
Sbjct: 890  VDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACH---PGYFVIQPWQEIHKLEVLMEEMI 946

Query: 712  EFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITI 771
             +Y   +  ++ +    +DQ   AK E+  W+R  + G+  +  V V  +D+G    + I
Sbjct: 947  LYYSVSEERHIAV---EKDQVYAAKVENK-WHRVLLKGILTNGLVSVYELDYGKHELVNI 1002

Query: 772  KDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILE 831
            + V+ + D F   P +A+  +LA +    +  QWS+EA   F    + K +   V  ++E
Sbjct: 1003 RKVQPLVDMFRKLPFQAVTAQLAGV----KCNQWSEEASMVFRNHVEKKPLVALVQTVIE 1058

Query: 832  -----DNVLLVELFDSLGAPEMTTTSIND 855
                 D  ++V L D+   P+ T T I+D
Sbjct: 1059 NANPWDRKVVVYLVDT-SLPD-TDTWIHD 1085



 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 84/391 (21%), Positives = 155/391 (39%), Gaps = 72/391 (18%)

Query: 670  PPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQ 729
            PP++       SV V  +++  +  ++ + G D     + +E+  K    +N +I  PVQ
Sbjct: 455  PPLMIPTEASPSVLVVELSNTNEVVIRYV-GKDYSAAQELMEDEMKEYYSKNPKIT-PVQ 512

Query: 730  ----DQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAP 785
                 Q      E+  W RA+VI      +++V YVD+G +  +      K+  +F +  
Sbjct: 513  AVNVGQLLAVNAEEDAWLRAQVISTE-ENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLS 571

Query: 786  EKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGA 845
             +A KCKLA +E                               +L D+  LV++ +SL  
Sbjct: 572  FQATKCKLAGLE-------------------------------VLSDDPDLVKVVESLTC 600

Query: 846  PEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSL 905
             ++    I D+         +I  ++         ++D S E+ I+     L  +  KSL
Sbjct: 601  GKIFAVEILDKA--------DIPLVV---------LYDTSGEDDININATCLKAICDKSL 643

Query: 906  P-NENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEE--KMIAAYENSKWEPVK 962
              +    ++Y     V + N+ S   +Y Q  +    LN L +  + I  Y + K    +
Sbjct: 644  EVHLQVDAMYTN---VKVTNICSDGTLYCQ--VPCKGLNKLSDLLRKIEDYFHCKHMTSE 698

Query: 963  WENDMHCAVKI---QDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLE---- 1015
                +    KI     K +W R +I  + +   ++V   D G    V V  LR++     
Sbjct: 699  CFVSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFL 758

Query: 1016 ENLKTMGRLSLECSLVDIRPAGGSDKWTATA 1046
            + +  +   +++C L D+  + G   WT  A
Sbjct: 759  QEMIAIPPQAIKCCLADLPQSIG--MWTPDA 787



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 23/101 (22%), Positives = 47/101 (46%), Gaps = 13/101 (12%)

Query: 1232 GEACAVRGSDTLWYRGKVMEVVGGAVRVQYLDHGFTEKIPQCHLYPILLYPDIPQFC--- 1288
            G+  AV   +  W R +V+      ++V Y+D+GF+E + +   Y +      P+FC   
Sbjct: 517  GQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKL-----NPKFCSLS 571

Query: 1289 ---IPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIME 1326
                 C+L     + +   PD ++V++ L   +   + I++
Sbjct: 572  FQATKCKLAGLEVLSD--DPDLVKVVESLTCGKIFAVEILD 610


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 4/138 (2%)

Query: 733 CVAKFEDGIWYRAKVIG-LPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKC 791
           C A   DG W+RA+V+       EVE++YVD+G   ++ +  +R+I+ +F+  P +  + 
Sbjct: 765 CAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEV 824

Query: 792 KLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTT 851
            L  + P     Q+S EA     E   +  +   V       + L++L+  +G       
Sbjct: 825 LLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGD---EVV 881

Query: 852 SINDQLVKEGLASYEIGY 869
            IN  LV+ GLA +   Y
Sbjct: 882 LINRSLVERGLAQWVDSY 899



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 15/139 (10%)

Query: 1486 CLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIK 1545
            C A   DG W+RA++VA  E     + +++VDYG   ++ ++ L QI S  +  P +  +
Sbjct: 765  CAAPGADGAWWRAQVVASYE-ETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAE 823

Query: 1546 VLLAGFKPPLRDLGETRIPYCPKWSMEALWAMIDCLQGKQLYAVSMAPAPE-----QIVT 1600
            VLL    P   D          ++S EA  AM +      L A   + +P      Q+ +
Sbjct: 824  VLLDSVMPLSDD---------DQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWS 874

Query: 1601 LYDDEQHPVHMPLVEMGLA 1619
            +  DE   ++  LVE GLA
Sbjct: 875  VVGDEVVLINRSLVERGLA 893



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 49/188 (26%), Positives = 82/188 (43%), Gaps = 11/188 (5%)

Query: 920  VHICNVISPEKIYVQWLL--TENLLNSLEEKMIAAYENSKWE--PVKWENDMHCAVKIQD 975
            V + N ++   ++VQ     T + L SL+++M   Y        P   E  + CA    D
Sbjct: 712  VIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGAD 771

Query: 976  KNQWRRGQIIRMVTDTL-VEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIR 1034
               W R Q++    +T  VE+   D G    V VD LR++  +  T+     E  L  + 
Sbjct: 772  -GAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVM 830

Query: 1035 PAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSK 1094
            P    D+++  A D     +TG  A ++ QV S    +   LP+         E V +++
Sbjct: 831  PLSDDDQFSPEA-DAAMSEMTGNTA-LLAQVTS---YSPTGLPLIQLWSVVGDEVVLINR 885

Query: 1095 YLIKKGLA 1102
             L+++GLA
Sbjct: 886  SLVERGLA 893


>gi|77404397 staphylococcal nuclease domain containing 1 [Homo
           sapiens]
          Length = 910

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 73/317 (23%), Positives = 131/317 (41%), Gaps = 33/317 (10%)

Query: 564 GLLKDIQPLAQPCSL--KDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIV 621
           GL+++ +P ++  +L  K++V Q      E E +VE +    N    + +      VL+V
Sbjct: 569 GLVQEGEPFSEEATLFTKELVLQR-----EVEVEVESMDKAGNFIGWLHIDGANLSVLLV 623

Query: 622 DLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDV- 680
           +      +  +++     +  L   E AK K + + +H+E+       P +  KE +   
Sbjct: 624 EHALSKVH-FTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSASY 682

Query: 681 -SVTVCHINSPGDFYLQLIE-GLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFE 738
             V V  I     FY+Q +E G  +  L++ +     S          P + + C+AKF 
Sbjct: 683 KPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSY-APRRGEFCIAKFV 741

Query: 739 DGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLN--APEKAIKCKLAYI 796
           DG WYRA+V  +    ++ V Y+D+GN   +    +  +   F     P +A +   A+I
Sbjct: 742 DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFI 801

Query: 797 EPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQ 856
           +  +             ++ A+   +   V  I     LL     S G P +T    + +
Sbjct: 802 QVPQ-------------DDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSK 848

Query: 857 ------LVKEGLASYEI 867
                 LVKEGL   E+
Sbjct: 849 GDVGLGLVKEGLVMVEV 865



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 66/329 (20%), Positives = 136/329 (41%), Gaps = 52/329 (15%)

Query: 1300 GNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSE 1359
            G  +  +A    ++L+ +R+V++ +  + K         L+ DG +LS  +  +      
Sbjct: 574  GEPFSEEATLFTKELVLQREVEVEVESMDKAG--NFIGWLHIDGANLSVLLVEHALSKVH 631

Query: 1360 HTEEM---LKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAV 1416
             T E     K    ++   K ++E+    +EE    E   P+L     S+   P  ++  
Sbjct: 632  FTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQ-PVEEVMPVLEEKERSASYKP--VFVT 688

Query: 1417 QVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEALPP 1476
            ++      ++++  +  +ET  Q                    L++ ++ +   + + PP
Sbjct: 689  EIT-----DDLHFYVQDVETGTQ--------------------LEKLMENMRNDIASHPP 723

Query: 1477 LTDF---RTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQI- 1532
            +      R    C+A++ DG WYRA++  ++  +P  I V ++DYG+   L   RL  + 
Sbjct: 724  VEGSYAPRRGEFCIAKFVDGEWYRARVEKVE--SPAKIHVFYIDYGNREVLPSTRLGTLS 781

Query: 1533 PSHLMR-YPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEALWAMIDCLQGKQ--LYAV 1589
            P+   R  PA+A +   A  + P  D   T          +A+ +++  +Q  Q  L   
Sbjct: 782  PAFSTRVLPAQATEYAFAFIQVPQDDDART----------DAVDSVVRDIQNTQCLLNVE 831

Query: 1590 SMAPAPEQIVTLYDDEQHPVHMPLVEMGL 1618
             ++     +   + D +  V + LV+ GL
Sbjct: 832  HLSAGCPHVTLQFADSKGDVGLGLVKEGL 860



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 37/124 (29%), Positives = 54/124 (43%), Gaps = 10/124 (8%)

Query: 1153 EQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMTN 1212
            EQ V E    + E   +  YKP  +  +   +     V D  T   + KL E     M N
Sbjct: 663  EQPVEEVMPVLEEKERSASYKPVFVTEIT--DDLHFYVQDVETGTQLEKLME----NMRN 716

Query: 1213 EIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGA-VRVQYLDHGFTEKIP 1271
            +I S+    G   P   ++GE C  +  D  WYR +V +V   A + V Y+D+G  E +P
Sbjct: 717  DIASHPPVEGSYAP---RRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLP 773

Query: 1272 QCHL 1275
               L
Sbjct: 774  STRL 777



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 28/129 (21%)

Query: 404 IEEII----EDNVESSAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLD 459
           +EE++    E    +S + VFV+ + D  HFY++    ++    LEK +    N  +   
Sbjct: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQ---DVETGTQLEKLMENMRNDIASHP 722

Query: 460 PSDILELGAR--IFVSSIKNGMWCRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFM 517
           P +      R    ++   +G W R  + +                   V   A I +F 
Sbjct: 723 PVEGSYAPRRGEFCIAKFVDGEWYRARVEK-------------------VESPAKIHVFY 763

Query: 518 VDFGNSEVL 526
           +D+GN EVL
Sbjct: 764 IDYGNREVL 772


>gi|40255178 tudor domain containing 5 [Homo sapiens]
          Length = 981

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 46/170 (27%), Positives = 83/170 (48%), Gaps = 10/170 (5%)

Query: 680 VSVTVCHINSPGDFYLQLI--EGLDILF-LLKTIEEFYKSEDGENLEIL--CPVQDQ--A 732
           + V V +I SP  FY+++   +  ++L  ++  +   Y ++   +  ++  C +Q     
Sbjct: 473 IGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLC 532

Query: 733 CVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCK 792
           CV   ED  WYR  +  +   QEVEV Y DFGN   +    +R +K  +   P +AI C 
Sbjct: 533 CVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCS 592

Query: 793 LAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDS 842
           LA++ P +    W+ +A  +F++    K +   V+    D +L + L D+
Sbjct: 593 LAWVRPVEE--HWTSKAILQFQKLCGLKPLV-GVVDEYVDGILNIFLCDT 639



 Score = 38.1 bits (87), Expect = 0.070
 Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 22/172 (12%)

Query: 883  DPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN-- 940
            D  P+ + + ++  L P+   SL            + V +  +ISP + Y++    ++  
Sbjct: 450  DIPPDAVPNKKLCRLPPLDTSSL------------IGVFVEYIISPSQFYIRIYSRDSSE 497

Query: 941  LLNSLEEKMIAAYENSKWE-----PVKWENDMH-CAVKIQDKNQWRRGQIIRMVTDTLVE 994
            LL  +  +M   Y N         P  +    H C V+I +   W R  I R++    VE
Sbjct: 498  LLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVE 557

Query: 995  VLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATA 1046
            V   D G   +V    LR L+     +   ++ CSL  +RP    + WT+ A
Sbjct: 558  VFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPV--EEHWTSKA 607



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 30/90 (33%), Positives = 38/90 (42%), Gaps = 3/90 (3%)

Query: 1228 FWKKGEACAVRGS-DTLWYRGKVMEVVGGA-VRVQYLDHGFTEKIPQCHL-YPILLYPDI 1284
            F + G  C VR S D  WYR  +  V+    V V Y D G    + +  L +    Y  +
Sbjct: 525  FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584

Query: 1285 PQFCIPCQLHNTTPVGNVWQPDAIEVLQQL 1314
            P   IPC L    PV   W   AI   Q+L
Sbjct: 585  PAQAIPCSLAWVRPVEEHWTSKAILQFQKL 614


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 37/144 (25%), Positives = 73/144 (50%), Gaps = 11/144 (7%)

Query: 727  PVQDQACVAKFED---GIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLN 783
            P  D  C+A F D     ++RA+V+ + G+   EV +VD+GN + + +  + +I  +FL 
Sbjct: 945  PHPDLVCLAPFADFDKQRYFRAQVLYVSGNS-AEVFFVDYGNKSHVDLHLLMEIPCQFLE 1003

Query: 784  APEKAIKCKLAYIEPYKRTM----QWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVEL 839
             P +A++ K+  + P  +++     WS  A + F        +   V  ++  +VL V++
Sbjct: 1004 LPFQALEFKICKMRPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVH-SVLHVDV 1062

Query: 840  FDSLGAPEMTTTSINDQLVKEGLA 863
            +   G  +    +I D L+++G A
Sbjct: 1063 YQYSGVQD--AINIRDVLIQQGYA 1084



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 28/108 (25%), Positives = 57/108 (52%), Gaps = 7/108 (6%)

Query: 1454 ESESESLDEALQRVNKKVEALPPLTDFRTEMPCLA---EYDDGLWYRAKIVAIKEFNPLS 1510
            E+ SE L +    +N+ +  +P  T    ++ CLA   ++D   ++RA+++ +   +  S
Sbjct: 920  ENNSEILKKLTAEINQ-LTLVPLPTHPHPDLVCLAPFADFDKQRYFRAQVLYV---SGNS 975

Query: 1511 ILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDL 1558
              V FVDYG+ + + L+ L +IP   +  P +A++  +   +P  + L
Sbjct: 976  AEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSAKSL 1023


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score = 40.8 bits (94), Expect = 0.011
 Identities = 53/297 (17%), Positives = 112/297 (37%), Gaps = 38/297 (12%)

Query: 49  LQCGHAFCE--LCLLMTEECTTIICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKT 106
           + CGH+FC   LCL   E    + CP C     ++ +  +       K  S+  + +P+ 
Sbjct: 28  IDCGHSFCRPCLCLCSEEGRAPMRCPSCR---KISEKPNFNTNVVLKKLSSLARQTRPQN 84

Query: 107 IKN---------------CSQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEI 151
           I +               C  D +      +   E  A +    +  +A        +E+
Sbjct: 85  INSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSP-IGWAAEECREKLIKEM 143

Query: 152 DEALNTAHHSFEQLSIAGKALEHMQKQTIEERERVIEVVEKQFDQLLAFFDSRKKNLCEE 211
           D        +   L+   +   H  K  +  R+R+I +   Q+ ++  F D  ++   + 
Sbjct: 144 DYLWEINQETRNNLNQETRTF-HSLKDYVSVRKRIITI---QYQKMPIFLDEEEQRHLQA 199

Query: 212 FARTTDDYLSNLIKAKSYIEEKKNNLNAAMNIARALQLSPSLRTYC---DLNQIIRTLQL 268
             R  ++    L         + + +    ++ R   +   L   C   D+  +     +
Sbjct: 200 LEREAEELFQQL---------QDSQVRMTQHLERMKDMYRELWETCHVPDVELLQDVRNV 250

Query: 269 TSDSELAQVSSPQLRNPPRLSVNCSEIICMFNNMGKIEFRDSTKCYPQENEIRQNVQ 325
           ++ ++LAQ+  PQ  NP   S   + ++ M NN  +++   ST+  P    + ++V+
Sbjct: 251 SARTDLAQMQKPQPVNPELTSWCITGVLDMLNNF-RVDSALSTEMIPCYISLSEDVR 306


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score = 40.0 bits (92), Expect = 0.018
 Identities = 57/262 (21%), Positives = 111/262 (42%), Gaps = 45/262 (17%)

Query: 50  QCGHAFCELCLLMT--EECTTIICPDCEVATAVNTRQRYYPMAG-YIKEDSIMEKLQPKT 106
           +CGH+FC +CLL +  E  T + CP+C           +  + G + + +  + +L    
Sbjct: 30  ECGHSFCLVCLLRSWEEHNTPLSCPEC-----------WRTLEGPHFQSNERLGRLASIA 78

Query: 107 IKNCSQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLS 166
            +  SQ  +   +Q + G  R  +T K L +           E+   A     H   ++ 
Sbjct: 79  RQLRSQVLQSEDEQGSYG--RMPTTAKALSDD----------EQGGSAFVAQSHGANRVH 126

Query: 167 IAGKALEHMQKQTIEERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDD-YLSNLIK 225
           ++ +A EH  ++ ++E   ++ V  K+   +L     R K LC+E  +T     +S  +K
Sbjct: 127 LSSEAEEH-HREKLQEILNLLRVRRKEAQAVLTHEKERVK-LCQEETKTCKQVVVSEYMK 184

Query: 226 AKSYI------------EEKKNNLNAAMNIARALQLSPSLRTYCD-LNQIIRTLQLTSDS 272
              ++            +E+K N+    N    ++L+  +R+    + QI  + Q ++  
Sbjct: 185 MHQFLKEEEQLQLQLLEQEEKENMRKLRN--NEIKLTQQIRSLSKMIAQIESSSQSSAFE 242

Query: 273 ELAQVSSPQLRNPPRLSVNCSE 294
            L +V     R+ P L + C E
Sbjct: 243 SLEEVRGALERSEP-LLLQCPE 263


>gi|119220603 ring finger protein 208 [Homo sapiens]
          Length = 261

 Score = 39.7 bits (91), Expect = 0.024
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 13/105 (12%)

Query: 7   KTGPSRSSYQRMGRKSQPWGAAEIQCTRCGRRVSRSSGHHCELQCGHAFCELCL-LMTEE 65
           + GPS S+       S       ++C  CG   + +      L C H+ CE CL ++ E 
Sbjct: 124 RPGPSASA------ASSAAAGEPLECPTCGHSYNVTQRRPRVLSCLHSVCEQCLQILYES 177

Query: 66  CTT---IICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKTI 107
           C     I CP C   T + T    Y +A      SI+ +L P+ +
Sbjct: 178 CPKYKFISCPTCRRETVLFTD---YGLAALAVNTSILSRLPPEAL 219


>gi|209862805 SPRY domain containing 5 [Homo sapiens]
          Length = 452

 Score = 38.9 bits (89), Expect = 0.041
 Identities = 43/210 (20%), Positives = 89/210 (42%), Gaps = 32/210 (15%)

Query: 49  LQCGHAFCELCLLMTEECTTII--CPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKT 106
           + CGH+FC  CL +  + T ++  C +C+      TRQR       +  D  ++ +    
Sbjct: 28  IDCGHSFCRPCLYLNWQDTAVLAQCSECK----KTTRQR------NLNTDICLKNMAFIA 77

Query: 107 IKNCSQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALN-----TAHHS 161
            K   + F  + +Q+  G+ R        ++ S + L  + ++E    ++      A   
Sbjct: 78  RKASLRQFLSSEEQI-CGMHRETKKMFCEVDKSLLCLPCSNSQEHRNHIHCPIEWAAEER 136

Query: 162 FEQL-----SIAGKALEHMQKQTIE-ERERV--------IEVVEKQFDQLLAFFDSRKKN 207
            E+L     S+  KA E+++   +E  R R         IE +  ++ ++ AF    +++
Sbjct: 137 REELLKKMQSLWEKACENLRNLNMETTRTRCWKDYVSLRIEAIRAEYQKMPAFLHEEEQH 196

Query: 208 LCEEFARTTDDYLSNLIKAKSYIEEKKNNL 237
             E   +  +D    L ++K+ +E  +  L
Sbjct: 197 HLERLRKEGEDIFQQLNESKARMEHSRELL 226


>gi|221219026 pleckstrin homology-like domain, family B, member 1
            isoform b [Homo sapiens]
          Length = 1319

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 9/133 (6%)

Query: 111  SQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGK 170
            S D  +T+  ++TG   + S D     SSA  LD    EE+++ L  AH    +L  + +
Sbjct: 1069 SSDSMETS--ISTGGNSACSPDNM---SSASGLDMGKIEEMEKMLKEAHAEKNRLMESRE 1123

Query: 171  ALEHMQKQTIEERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYI 230
                +++Q +EE  R  E VE++    L    +R++ L E+  +  +   S       Y+
Sbjct: 1124 REMELRRQALEEERRRREQVERR----LQSESARRQQLVEKEVKMREKQFSQARPLTRYL 1179

Query: 231  EEKKNNLNAAMNI 243
              +K + +   +I
Sbjct: 1180 PIRKEDFDLKTHI 1192


>gi|221219024 pleckstrin homology-like domain, family B, member 1
            isoform a [Homo sapiens]
          Length = 1377

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 9/133 (6%)

Query: 111  SQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGK 170
            S D  +T+  ++TG   + S D     SSA  LD    EE+++ L  AH    +L  + +
Sbjct: 1116 SSDSMETS--ISTGGNSACSPDNM---SSASGLDMGKIEEMEKMLKEAHAEKNRLMESRE 1170

Query: 171  ALEHMQKQTIEERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYI 230
                +++Q +EE  R  E VE++    L    +R++ L E+  +  +   S       Y+
Sbjct: 1171 REMELRRQALEEERRRREQVERR----LQSESARRQQLVEKEVKMREKQFSQARPLTRYL 1226

Query: 231  EEKKNNLNAAMNI 243
              +K + +   +I
Sbjct: 1227 PIRKEDFDLKTHI 1239


>gi|38424073 pleckstrin homology-like domain, family B, member 1
            isoform a [Homo sapiens]
          Length = 1377

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 9/133 (6%)

Query: 111  SQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGK 170
            S D  +T+  ++TG   + S D     SSA  LD    EE+++ L  AH    +L  + +
Sbjct: 1116 SSDSMETS--ISTGGNSACSPDNM---SSASGLDMGKIEEMEKMLKEAHAEKNRLMESRE 1170

Query: 171  ALEHMQKQTIEERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYI 230
                +++Q +EE  R  E VE++    L    +R++ L E+  +  +   S       Y+
Sbjct: 1171 REMELRRQALEEERRRREQVERR----LQSESARRQQLVEKEVKMREKQFSQARPLTRYL 1226

Query: 231  EEKKNNLNAAMNI 243
              +K + +   +I
Sbjct: 1227 PIRKEDFDLKTHI 1239


>gi|31377566 ring finger protein 168 [Homo sapiens]
          Length = 571

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 38/169 (22%), Positives = 65/169 (38%), Gaps = 13/169 (7%)

Query: 49  LQCGHAFCELCLLMTEECTTIICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKTIK 108
           L C H  C+ C   T E  ++ CP C     V++  RY+     +    +   +Q    +
Sbjct: 29  LPCNHTLCKPCFQSTVEKASLCCPFCR--RRVSSWTRYHTRRNSLVNVELWTIIQKHYPR 86

Query: 109 NC-----SQDFKKTAD--QLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHS 161
            C      Q+ ++ AD  Q    L +     +      + +     A E +E  N A   
Sbjct: 87  ECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEE--NKASEE 144

Query: 162 FEQLSIAGKALEHMQKQTIEERERVIEVVEKQFDQLLAFFDSRKKNLCE 210
           + Q  +A +  E  +K+  E+R R +E   K  ++L         N CE
Sbjct: 145 YIQRLLAEE--EEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCE 191


>gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 15/40 (37%), Positives = 25/40 (62%)

Query: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKI 777
           ED  WYR KV+ +   ++  V+Y+D+GNT  +   D+ +I
Sbjct: 68  EDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEI 107



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 1491 DDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAG 1550
            +D  WYR K++ I        LV+++DYG+T  L  + + +IP  L ++ + A K  L G
Sbjct: 68   EDQCWYRCKVLKIISVE--KCLVRYIDYGNTEILNRSDIVEIPLEL-QFSSVAKKYKLWG 124

Query: 1551 FKPP 1554
               P
Sbjct: 125  LHIP 128


>gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
          Length = 1019

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 15/40 (37%), Positives = 25/40 (62%)

Query: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKI 777
           ED  WYR KV+ +   ++  V+Y+D+GNT  +   D+ +I
Sbjct: 91  EDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEI 130



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 1491 DDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAG 1550
            +D  WYR K++ I        LV+++DYG+T  L  + + +IP  L ++ + A K  L G
Sbjct: 91   EDQCWYRCKVLKIISVE--KCLVRYIDYGNTEILNRSDIVEIPLEL-QFSSVAKKYKLWG 147

Query: 1551 FKPP 1554
               P
Sbjct: 148  LHIP 151


>gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 15/40 (37%), Positives = 25/40 (62%)

Query: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKI 777
           ED  WYR KV+ +   ++  V+Y+D+GNT  +   D+ +I
Sbjct: 68  EDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEI 107



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 1491 DDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAG 1550
            +D  WYR K++ I        LV+++DYG+T  L  + + +IP  L ++ + A K  L G
Sbjct: 68   EDQCWYRCKVLKIISVE--KCLVRYIDYGNTEILNRSDIVEIPLEL-QFSSVAKKYKLWG 124

Query: 1551 FKPP 1554
               P
Sbjct: 125  LHIP 128


>gi|24432013 zinc finger protein 668 [Homo sapiens]
          Length = 619

 Score = 35.8 bits (81), Expect = 0.35
 Identities = 25/111 (22%), Positives = 43/111 (38%), Gaps = 25/111 (22%)

Query: 26  GAAEIQCTRCGRRVSRSSGHHCELQ------------CGHAFCELCLLMTEECT-----T 68
           G     C+ CG+  SRSS   C  +            CG  F +L    + E T      
Sbjct: 220 GERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKP 279

Query: 69  IICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKTIKNCSQDFKKTAD 119
            +CP C         + +   + + +     E+++P   + C +DF++ AD
Sbjct: 280 FLCPRC--------GRMFSDPSSFRRHQRAHEEVKPYHCEKCGKDFRQPAD 322


>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
          Length = 1236

 Score = 35.4 bits (80), Expect = 0.45
 Identities = 30/128 (23%), Positives = 63/128 (49%), Gaps = 9/128 (7%)

Query: 934  QWLLTENLLNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLV 993
            +++ T +L++ L++  I   E+S+ + VK    +     ++DKN   +   ++ +   +V
Sbjct: 23   RFMATSDLMSELQKDSIQLDEDSERKVVKMLLRL-----LEDKNGEVQNLAVKCLGPLVV 77

Query: 994  EVLLYDVGVELVVNVDC--LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS 1051
            +V  Y V  E +V+  C  +R  +E L+ +  + L+  L ++ PA          C  ++
Sbjct: 78   KVKEYQV--ETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCRKIT 135

Query: 1052 LYLTGAVA 1059
              LT A+A
Sbjct: 136  GQLTSAIA 143


>gi|109637791 transcription factor-like nuclear regulator [Homo
            sapiens]
          Length = 2624

 Score = 35.4 bits (80), Expect = 0.45
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 2/98 (2%)

Query: 1068 EENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLE 1127
            EE    W +  K F ++++    D   +L++K LA  E+R      +HSL EK    P +
Sbjct: 344  EEKTNGWRID-KAF-QEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRK 401

Query: 1128 QEDSVVTNCIKTNFDPDKKTADIISEQKVSEFQEKILE 1165
                    C   N DPD+  +  IS+ + S+   + +E
Sbjct: 402  NVKVKKVACEGVNNDPDESMSSRISDTERSQKDAQTVE 439


>gi|226442736 ring finger protein 222 [Homo sapiens]
          Length = 220

 Score = 35.0 bits (79), Expect = 0.59
 Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 8/66 (12%)

Query: 31 QCTRCGRRVSRSSGHHCELQCGHAFCELCLLMTEECT--------TIICPDCEVATAVNT 82
          +C  C  +     G    L CGH FC  CL+     T        T++CP C   T ++ 
Sbjct: 13 ECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTLVCPICRYVTFLSK 72

Query: 83 RQRYYP 88
          +   +P
Sbjct: 73 KSSRWP 78


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,319,632
Number of Sequences: 37866
Number of extensions: 2900788
Number of successful extensions: 10448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 10117
Number of HSP's gapped (non-prelim): 353
length of query: 1623
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1507
effective length of database: 13,855,062
effective search space: 20879578434
effective search space used: 20879578434
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.