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Search of human proteins with 93277099
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93277099 solute carrier organic anion transporter family,
member 6A1 [Homo sapiens]
(719 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93277099 solute carrier organic anion transporter family, mem... 1456 0.0
gi|38679890 solute carrier organic anion transporter family, mem... 525 e-149
gi|39777594 solute carrier organic anion transporter family memb... 356 5e-98
gi|225637473 solute carrier organic anion transporter family, me... 265 8e-71
gi|225543525 solute carrier organic anion transporter family, me... 229 5e-60
gi|222831575 solute carrier organic anion transporter family, me... 228 1e-59
gi|222831573 solute carrier organic anion transporter family, me... 228 1e-59
gi|225637475 solute carrier organic anion transporter family, me... 226 7e-59
gi|8394291 solute carrier organic anion transporter family, memb... 224 2e-58
gi|225543118 solute carrier organic anion transporter family, me... 216 6e-56
gi|225637477 solute carrier organic anion transporter family, me... 215 1e-55
gi|188528663 solute carrier organic anion transporter family, me... 214 2e-55
gi|9790233 solute carrier organic anion transporter family, memb... 213 7e-55
gi|223634012 solute carrier organic anion transporter family, me... 201 3e-51
gi|6005820 solute carrier organic anion transporter family, memb... 201 3e-51
gi|225543114 solute carrier organic anion transporter family, me... 198 2e-50
gi|225543116 solute carrier organic anion transporter family, me... 194 2e-49
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 191 2e-48
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 191 2e-48
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 187 3e-47
gi|223634014 solute carrier organic anion transporter family, me... 176 5e-44
gi|28875799 cholecystokinin B receptor [Homo sapiens] 33 0.71
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 32 1.6
gi|4506971 solute carrier family 10, member 1 [Homo sapiens] 30 6.0
gi|100913198 six transmembrane epithelial antigen of the prostat... 30 6.0
gi|100913194 six transmembrane epithelial antigen of the prostat... 30 6.0
gi|100913196 six transmembrane epithelial antigen of the prostat... 30 6.0
gi|215272390 solute carrier family 18 (vesicular monoamine), mem... 30 7.8
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 1456 bits (3769), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MFVGVARHSGSQDEVSRGVEPLEAARAQPAKDRRAKGTPKSSKPGKKHRYLRLLPEALIR 60
MFVGVARHSGSQDEVSRGVEPLEAARAQPAKDRRAKGTPKSSKPGKKHRYLRLLPEALIR
Sbjct: 1 MFVGVARHSGSQDEVSRGVEPLEAARAQPAKDRRAKGTPKSSKPGKKHRYLRLLPEALIR 60
Query: 61 FGGFRKRKKAKSSVSKKPGEVDDSLEQPCGLGCLVSTCCECCNNIRCFMIFYCILLICQG 120
FGGFRKRKKAKSSVSKKPGEVDDSLEQPCGLGCLVSTCCECCNNIRCFMIFYCILLICQG
Sbjct: 61 FGGFRKRKKAKSSVSKKPGEVDDSLEQPCGLGCLVSTCCECCNNIRCFMIFYCILLICQG 120
Query: 121 VVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAFYGDRKKVIWFVASSFL 180
VVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAFYGDRKKVIWFVASSFL
Sbjct: 121 VVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAFYGDRKKVIWFVASSFL 180
Query: 181 IGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQG 240
IGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQG
Sbjct: 181 IGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQG 240
Query: 241 IAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVKVPENTTSATN 300
IAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVKVPENTTSATN
Sbjct: 241 IAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVKVPENTTSATN 300
Query: 301 TTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRL 360
TTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRL
Sbjct: 301 TTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRL 360
Query: 361 KDLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTV 420
KDLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTV
Sbjct: 361 KDLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTV 420
Query: 421 ATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPV 480
ATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPV
Sbjct: 421 ATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPV 480
Query: 481 QFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ 540
QFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ
Sbjct: 481 QFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ 540
Query: 541 KKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIV 600
KKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIV
Sbjct: 541 KKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIV 600
Query: 601 LAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIY 660
LAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIY
Sbjct: 601 LAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIY 660
Query: 661 NKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNENTDFPDVTVKNPKVKKKEETDL 719
NKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNENTDFPDVTVKNPKVKKKEETDL
Sbjct: 661 NKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNENTDFPDVTVKNPKVKKKEETDL 719
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 525 bits (1353), Expect = e-149
Identities = 263/598 (43%), Positives = 375/598 (62%), Gaps = 6/598 (1%)
Query: 98 CCECCNNIRCFMIFYCILLICQGVVF-GLIDVSIGDFQKEYQLKTIEKLALEKSYDISSG 156
C + CN F++ YC+L + QG+V GL+++SI +K Y++K+ + SYDIS
Sbjct: 97 CLQRCNTPGGFLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFC 156
Query: 157 LVAIFIAFYGDR-KKVIWFVASSFLIGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVS 215
L+++F++F+G+R K W ++F+IGLG+L+ + P + ED C + +
Sbjct: 157 LLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNST 216
Query: 216 GCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSM 275
C SS S S YL FILGQ + G G PLY LG F+D++V TH + +Y+G S+
Sbjct: 217 SCTSSTSSL-SNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSI 275
Query: 276 IGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCF 335
+G A+GYVLG L+ + + +T V P WL WWI FL + + AW +IP SCF
Sbjct: 276 LGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCF 335
Query: 336 PNNMPGSTRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICLALSKATE 395
P ++PG+ I+A K Q H +S D+K G +IKD AAL LMKN V +CL LS ++E
Sbjct: 336 PKHLPGTAEIQAGKTSQAHQSNSNA-DVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSE 394
Query: 396 YLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALM 455
L+ G + FLP ++ENQF LT + A TL G VLIPG ALGQ+LGG +VS M+CK M
Sbjct: 395 ALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTM 454
Query: 456 RFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSS 515
+F + TS ++L L ++ +C FAG++E Y+GTG+LGNL APCN C CS S Y
Sbjct: 455 KFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLIAPCNANCNCSRSYYYP 514
Query: 516 ICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCI-KEGLITADAEGDFIDARPGKCDAK 574
+CG D ++YFSPCFAGC+ A + K+YYNCSCI ++ IT+ AE +A+ GKC+
Sbjct: 515 VCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKCETH 573
Query: 575 CYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSI 634
C KLP+F+ F +IF+ +G PI +++ R V + RSLALG+ +++LR+ GTIPGP I
Sbjct: 574 CAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPII 633
Query: 635 FKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYK 692
F + +++CIL D+N CG G CWIY+ KMA +LV I CK+ T+ F A F+YK
Sbjct: 634 FGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYK 691
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 356 bits (913), Expect = 5e-98
Identities = 210/630 (33%), Positives = 329/630 (52%), Gaps = 36/630 (5%)
Query: 89 CGLGCLVSTCCECCNNIRCFMIFYCILLICQGV-VFGLIDVSIGDFQKEYQLKTIEKLAL 147
CG C + N + + F C QG+ V G I+ I ++ Y L + + +
Sbjct: 86 CGWWAFAPPCLQVLNTPKGILFFLCAAAFLQGMTVNGFINTVITSLERRYDLHSYQSGLI 145
Query: 148 EKSYDISSGLVAIFIAFYGDR-KKVIWFVASSFLIGLGSLLCAFPSINEENKQSKV--GI 204
SYDI++ L F++++G K W L+G GSL+ A P + ++ G+
Sbjct: 146 ASSYDIAACLCLTFVSYFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGV 205
Query: 205 EDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAG 264
V +SG+S +Y F+LGQ + G+ PLY LG+T++DENV + +
Sbjct: 206 RTCPANPGAVCADSTSGLS---RYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSP 262
Query: 265 IYLGIAECTSMIGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVV 324
+Y+ I +++G A GY++G L+ + T T + SP W+ WW+ FL +
Sbjct: 263 VYIAIFYTAAILGPAAGYLIGGALLNI--YTEMGRRTELTTESPLWVGAWWVGFLGSGAA 320
Query: 325 AWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRLKDLK--------LGTNIKDLCAAL 376
A+ T +P+ +P +PGS R + ++H +LKD G I+DL ++
Sbjct: 321 AFFTAVPILGYPRQLPGSQRYAVMRAAEMH----QLKDSSRGEASNPDFGKTIRDLPLSI 376
Query: 377 WILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALG 436
W+L+KNP I L L+ ATE +I G S F P +LE+QF L+ + A TL G +++P G G
Sbjct: 377 WLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGG 436
Query: 437 QLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGT---- 492
LGG V+ L + A+++F + +V+SL L + + + C V AG+ Y G+
Sbjct: 437 TFLGGFFVNKLRLRGSAVIKFCLFCTVVSL-LGILVFSLHCPSVPMAGVTASYGGSLLPE 495
Query: 493 GKLGNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQN--QKKMYYNCSCI 550
G L NLTAPCN C C YS +CG D + YFS C AGC + N +K+Y +CSCI
Sbjct: 496 GHL-NLTAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCI 554
Query: 551 KEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDK 610
+ L F A GKC + C + PL + FIF + F+ S +P + A R V D
Sbjct: 555 PQNL-----SSGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDP 609
Query: 611 LRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLV 670
RS ALG+ ++++RI G IPGP F + +C+L ++CG G C +Y + M+ ++
Sbjct: 610 QRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQNSAMSRYIL 668
Query: 671 GICFLCKLCTIIFTTIAFFIYKRRLNENTD 700
+ L K+ ++F IA F+YK L+E++D
Sbjct: 669 IMGLLYKVLGVLFFAIACFLYK-PLSESSD 697
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 265 bits (678), Expect = 8e-71
Identities = 170/639 (26%), Positives = 290/639 (45%), Gaps = 57/639 (8%)
Query: 106 RCFMIFYCILLICQGV-VFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAF 164
RCF++ C L Q + V G + I ++ Y LK+ E L +DI + +V +F+++
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 165 YGDR-KKVIWFVASSFLIGLGSLLCAFP-------SINEENKQSKVGIEDICE------E 210
+G R ++ +W LI G+ L A P I E N + + +C+
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPN--DGLCQGGNSTAT 245
Query: 211 IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIA 270
++ + + SG + Y++ FI Q + G+ P+Y LG T++D+NV ++ +YL I
Sbjct: 246 LEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
Query: 271 ECTSMIGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLI 330
+G A+GY+LG L+ + + + N+ P ++ WW FL A+ + +
Sbjct: 306 YVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQND--PRFIGNWWSGFLLCAIAMFLVIF 363
Query: 331 PLSCFPNNMPGSTRIKARKRKQLHFF----------------DSRLKDLKLGTNIKDLCA 374
P+ FP +P + K +K+ + D ++ + G +++DL
Sbjct: 364 PMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPR 423
Query: 375 ALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGA 434
A ++ N + ++LS E ++ F+P ++E+QF + + A+ G++++P
Sbjct: 424 AAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAG 483
Query: 435 LGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK 494
+G +LGG I+ L++ + + M+ S +SL+ + V C + GIN Y
Sbjct: 484 VGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPS 543
Query: 495 L----GNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNCSC 549
L NLT CN C C Y +CG D I YF+PC AGC S + Y C+C
Sbjct: 544 LTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTC 603
Query: 550 IK-EGLITADAEGDFIDAR---------------PGKCDAKCYKLPLFIAFIFSTLIFSG 593
++ +IT G R GKC C L F+ F+F +
Sbjct: 604 VQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITA 663
Query: 594 FSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGH 653
+ ++ R V D+ R ALG+ +V+LR IP P F +T+C+L +CG
Sbjct: 664 CAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGV 722
Query: 654 TGRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYK 692
G CW YN T F+ G+ K IF +A++ K
Sbjct: 723 QGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 761
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 229 bits (585), Expect = 5e-60
Identities = 155/640 (24%), Positives = 283/640 (44%), Gaps = 54/640 (8%)
Query: 102 CNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIF 161
CN ++ F+ + I + + ++ SI ++ +++ + ++ S++I + LV +F
Sbjct: 24 CNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVF 83
Query: 162 IAFYGD---RKKVIWFVASSFLIGLGSLLCAFPSI-----------NEENKQSKVGIEDI 207
++++G R K+I F++G+G +L A P N + ++
Sbjct: 84 VSYFGSKLHRPKLIGI--GCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLST 141
Query: 208 CEEIKVVS-----------GCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDE 256
C +++S GC S+ Y+ +G ++GI P+ LG+++ID+
Sbjct: 142 CLINQILSLNRASPEIVGKGCLKESGSYMWIYV---FMGNMLRGIGETPIVPLGLSYIDD 198
Query: 257 NVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTW 314
+ +YLGI +MIG +G+ LG+ K V + + W+ W
Sbjct: 199 FAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAW 258
Query: 315 WINFLFAAVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSR----------LKDLK 364
W+NFL + + + + IP P P + + + LH ++ +
Sbjct: 259 WLNFLVSGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQGKN 317
Query: 365 LGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTL 424
+ N+ + ++ NP+ + L + IGA ++ Y+E Q+ + A L
Sbjct: 318 ITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANIL 377
Query: 425 AGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAG 484
G++ IP A G LGG I+ +++ + +F T+V+SL + F+ C AG
Sbjct: 378 LGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAG 437
Query: 485 INEDYDGTGKL-GNLTAP---CNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ 540
+ YDG + + P CN C C S + +CG + I Y SPC AGC S +
Sbjct: 438 LTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKK 497
Query: 541 KKMYYNCSCIKEGLITADAEGDFIDARPGKC---DAKCYKLPLFIAFIFSTLIFSGFSGV 597
++YNCSC++ + A G+C DA K F+A L FS G
Sbjct: 498 PIVFYNCSCLE----VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGT 553
Query: 598 PIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRC 657
V+ + ++V +L+SLALG +++R G I P F +T+CI N CG G C
Sbjct: 554 SHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSC 613
Query: 658 WIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNE 697
YN T + + +G+ + ++ +++ I + K++ E
Sbjct: 614 RTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQE 653
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 228 bits (581), Expect = 1e-59
Identities = 163/625 (26%), Positives = 281/625 (44%), Gaps = 56/625 (8%)
Query: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
C +NI+ F++ C L++ QG V + + ++ + L++ + + S++I + + +
Sbjct: 35 CFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALIL 94
Query: 161 FIAFYGDRKKVIWFVA-SSFLIGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQS 219
F++++G R + ++ LG+LL A P + + G E + V
Sbjct: 95 FVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANG 154
Query: 220 SG--------------ISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGI 265
SG + YL I Q + GI P+ LG+++ID++V + +
Sbjct: 155 SGGDEGPDPDLICRNRTATNMMYL-LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSL 213
Query: 266 YLGIAECTSMIGYALGYVLGAPLVKVPENTT--SATNTTVNNGSPEWLWTWWINFLFAAV 323
Y+GI + G A G++LG+ K+ + +N + P W+ WW FL
Sbjct: 214 YIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGA 273
Query: 324 VAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRLKDLKLGTNI------KDLCAALW 377
+ + + + + FP ++P + A + +Q + + K + D A+ +
Sbjct: 274 LLFFSSLLMFGFPQSLPPHSE-PAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCF 332
Query: 378 I-----------LMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAG 426
L+ NPV C+ L+ E V+ G + FL YLE QF LT + A L G
Sbjct: 333 QQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLG 392
Query: 427 LVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGIN 486
+ IP LG LGG++V L +S +R M+ +++S V +F+ C+ AG+
Sbjct: 393 MTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVT 452
Query: 487 EDYDGTGKLGNLT---APCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKM 543
Y + G+ +PCN C C + ++ +CG D I Y S CFAGC +
Sbjct: 453 VPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLT----- 507
Query: 544 YYNCSCIKEGLITADAEGDFIDARPGKCDAK-CYKLPL-FIAFIFSTLIFSGFSGVPIVL 601
C+C L T AE + PGKC + C + L F+ + + + P V+
Sbjct: 508 --GCAC----LTTVPAENATV--VPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVI 559
Query: 602 AMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYN 661
+ R V +L+S ALGV +++LR+ G IP P IF +++C+ CG G C +Y+
Sbjct: 560 ILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYD 618
Query: 662 KTKMAFLLVGICFLCK-LCTIIFTT 685
+L V I K I++TT
Sbjct: 619 NVVYRYLYVSIAIALKSFAFILYTT 643
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 228 bits (581), Expect = 1e-59
Identities = 163/625 (26%), Positives = 281/625 (44%), Gaps = 56/625 (8%)
Query: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
C +NI+ F++ C L++ QG V + + ++ + L++ + + S++I + + +
Sbjct: 35 CFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALIL 94
Query: 161 FIAFYGDRKKVIWFVA-SSFLIGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQS 219
F++++G R + ++ LG+LL A P + + G E + V
Sbjct: 95 FVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANG 154
Query: 220 SG--------------ISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGI 265
SG + YL I Q + GI P+ LG+++ID++V + +
Sbjct: 155 SGGDEGPDPDLICRNRTATNMMYL-LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSL 213
Query: 266 YLGIAECTSMIGYALGYVLGAPLVKVPENTT--SATNTTVNNGSPEWLWTWWINFLFAAV 323
Y+GI + G A G++LG+ K+ + +N + P W+ WW FL
Sbjct: 214 YIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGA 273
Query: 324 VAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRLKDLKLGTNI------KDLCAALW 377
+ + + + + FP ++P + A + +Q + + K + D A+ +
Sbjct: 274 LLFFSSLLMFGFPQSLPPHSE-PAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCF 332
Query: 378 I-----------LMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAG 426
L+ NPV C+ L+ E V+ G + FL YLE QF LT + A L G
Sbjct: 333 QQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLG 392
Query: 427 LVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGIN 486
+ IP LG LGG++V L +S +R M+ +++S V +F+ C+ AG+
Sbjct: 393 MTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVT 452
Query: 487 EDYDGTGKLGNLT---APCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKM 543
Y + G+ +PCN C C + ++ +CG D I Y S CFAGC +
Sbjct: 453 VPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLT----- 507
Query: 544 YYNCSCIKEGLITADAEGDFIDARPGKCDAK-CYKLPL-FIAFIFSTLIFSGFSGVPIVL 601
C+C L T AE + PGKC + C + L F+ + + + P V+
Sbjct: 508 --GCAC----LTTVPAENATV--VPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVI 559
Query: 602 AMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYN 661
+ R V +L+S ALGV +++LR+ G IP P IF +++C+ CG G C +Y+
Sbjct: 560 ILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYD 618
Query: 662 KTKMAFLLVGICFLCK-LCTIIFTT 685
+L V I K I++TT
Sbjct: 619 NVVYRYLYVSIAIALKSFAFILYTT 643
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 226 bits (575), Expect = 7e-59
Identities = 162/626 (25%), Positives = 271/626 (43%), Gaps = 86/626 (13%)
Query: 106 RCFMIFYCILLICQGV-VFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAF 164
RCF++ C L Q + V G + I ++ Y LK+ E L +DI + +V +F+++
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 165 YGDR-KKVIWFVASSFLIGLGSLLCAFP-------SINEENKQSKVGIEDICE------E 210
+G R ++ +W LI G+ L A P I E N + + +C+
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPN--DGLCQGGNSTAT 245
Query: 211 IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIA 270
++ + + SG + Y++ FI Q + G+ P+Y LG T++D+NV ++ +YL I
Sbjct: 246 LEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
Query: 271 ECTSMIGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLI 330
+G A+GY+LG L+ + + + N+ P ++ WW FL A+ + +
Sbjct: 306 YVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQND--PRFIGNWWSGFLLCAIAMFLVIF 363
Query: 331 PLSCFPNNMPGSTRIKARKRKQLHFFDSRLKD---LKLGTNIKDLCAALWILMKNPVLIC 387
P+ FP +P + +K+K+ F + D LK +N +
Sbjct: 364 PMFTFPKKLPP----RHKKKKKKKFSVDAVSDDDVLKEKSNNSE---------------- 403
Query: 388 LALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTL 447
+A + + +G + + G++++P +G +LGG I+ L
Sbjct: 404 ----QADKKVSSMGFGK------------------DVRGVIIVPSAGVGIVLGGYIIKKL 441
Query: 448 EMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLG----NLTAPCN 503
++ + + M+ S +SL+ + V C + GIN Y L NLT CN
Sbjct: 442 KLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCN 501
Query: 504 EKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNCSCIK-EGLITADAEG 561
C C Y +CG D I YF+PC AGC S + Y C+C++ +IT G
Sbjct: 502 VNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVG 561
Query: 562 DFIDAR---------------PGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRV 606
R GKC C L F+ F+F + + ++ R
Sbjct: 562 QRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRS 621
Query: 607 VPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMA 666
V D+ R ALG+ +V+LR IP P F +T+C+L +CG G CW YN T
Sbjct: 622 VEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFR 680
Query: 667 FLLVGICFLCKLCTIIFTTIAFFIYK 692
F+ G+ K IF +A++ K
Sbjct: 681 FVYFGLAAGLKFVGFIFIFLAWYSIK 706
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 224 bits (571), Expect = 2e-58
Identities = 146/639 (22%), Positives = 285/639 (44%), Gaps = 56/639 (8%)
Query: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
CC ++ F+ + + + G + +I ++ + + + ++ S++I + LV
Sbjct: 38 CCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVIT 97
Query: 161 FIAFYG---DRKKVIWFVASSFLIGLGSLLCAFPS------------------------I 193
F++++G R K+I A ++G+G+LL A P +
Sbjct: 98 FVSYFGAKLHRPKIIG--AGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCL 155
Query: 194 NEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITF 253
E + Q V + + + K+ + C+ + S + LG ++GI P+ LGI +
Sbjct: 156 LESSSQLPVSVMEKSKS-KISNECE---VDTSSSMWIYVFLGNLLRGIGETPIQPLGIAY 211
Query: 254 IDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWL 311
+D+ + +A Y+G + ++IG G++LG+ K V + + T+ P+W+
Sbjct: 212 LDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWV 271
Query: 312 WTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIK---ARKRKQLHFFDSRL-------K 361
WW+ +L A +++ +P P ++P S + + K D +
Sbjct: 272 GAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE 331
Query: 362 DLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVA 421
+ K+ +D +L L NPV + ++ + G + P Y+E Q+ + + A
Sbjct: 332 NAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRA 391
Query: 422 TTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQ 481
+ GL+ IP ALG GG+++ +S + + +SV +L + + + C
Sbjct: 392 NFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSD 451
Query: 482 FAGINEDYDGTGKLGN----LTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKA 537
AG+ Y GT + L + CN +C+CS + + +CG + I Y S C AGC S
Sbjct: 452 VAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNR 511
Query: 538 QNQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFS---GF 594
+ ++YNC+C+ I A G+ G+C +F+ F+ ++I S
Sbjct: 512 SGKNIIFYNCTCVG---IAASKSGNS-SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSL 567
Query: 595 SGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHT 654
G+P + + R + +L+S ALG+ + +R+ IP P F + +TSC+ +CG
Sbjct: 568 GGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSR 627
Query: 655 GRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKR 693
G C +Y+ + +G+ + +I+ + FI K+
Sbjct: 628 GSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 216 bits (550), Expect = 6e-56
Identities = 142/618 (22%), Positives = 275/618 (44%), Gaps = 56/618 (9%)
Query: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
CC ++ F+ + + + G + +I ++ + + + ++ S++I + LV
Sbjct: 38 CCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVIT 97
Query: 161 FIAFYG---DRKKVIWFVASSFLIGLGSLLCAFPS------------------------I 193
F++++G R K+I A ++G+G+LL A P +
Sbjct: 98 FVSYFGAKLHRPKIIG--AGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCL 155
Query: 194 NEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITF 253
E + Q V + + + K+ + C+ + S + LG ++GI P+ LGI +
Sbjct: 156 LESSSQLPVSVMEKSKS-KISNECE---VDTSSSMWIYVFLGNLLRGIGETPIQPLGIAY 211
Query: 254 IDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWL 311
+D+ + +A Y+G + ++IG G++LG+ K V + + T+ P+W+
Sbjct: 212 LDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWV 271
Query: 312 WTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIK---ARKRKQLHFFDSRL-------K 361
WW+ +L A +++ +P P ++P S + + K D +
Sbjct: 272 GAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE 331
Query: 362 DLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVA 421
+ K+ +D +L L NPV + ++ + G + P Y+E Q+ + + A
Sbjct: 332 NAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRA 391
Query: 422 TTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQ 481
+ GL+ IP ALG GG+++ +S + + +SV +L + + + C
Sbjct: 392 NFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSD 451
Query: 482 FAGINEDYDGTGKLGN----LTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKA 537
AG+ Y GT + L + CN +C+CS + + +CG + I Y S C AGC S
Sbjct: 452 VAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNR 511
Query: 538 QNQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFS---GF 594
+ ++YNC+C+ I A G+ G+C +F+ F+ ++I S
Sbjct: 512 SGKNIIFYNCTCVG---IAASKSGN-SSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSL 567
Query: 595 SGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHT 654
G+P + + R + +L+S ALG+ + +R+ IP P F + +TSC+ +CG
Sbjct: 568 GGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSR 627
Query: 655 GRCWIYNKTKMAFLLVGI 672
G C +Y+ + + I
Sbjct: 628 GSCRLYDSNVFRYQIKSI 645
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 215 bits (547), Expect = 1e-55
Identities = 138/533 (25%), Positives = 241/533 (45%), Gaps = 56/533 (10%)
Query: 106 RCFMIFYCILLICQGV-VFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAF 164
RCF++ C L Q + V G + I ++ Y LK+ E L +DI + +V +F+++
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 165 YGDR-KKVIWFVASSFLIGLGSLLCAFP-------SINEENKQSKVGIEDICE------E 210
+G R ++ +W LI G+ L A P I E N + + +C+
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPN--DGLCQGGNSTAT 245
Query: 211 IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIA 270
++ + + SG + Y++ FI Q + G+ P+Y LG T++D+NV ++ +YL I
Sbjct: 246 LEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
Query: 271 ECTSMIGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLI 330
+G A+GY+LG L+ + + + N+ P ++ WW FL A+ + +
Sbjct: 306 YVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQND--PRFIGNWWSGFLLCAIAMFLVIF 363
Query: 331 PLSCFPNNMPGSTRIKARKRKQLHFF----------------DSRLKDLKLGTNIKDLCA 374
P+ FP +P + K +K+ + D ++ + G +++DL
Sbjct: 364 PMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPR 423
Query: 375 ALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGA 434
A ++ N + ++LS E ++ F+P ++E+QF + + A+ G++++P
Sbjct: 424 AAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAG 483
Query: 435 LGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK 494
+G +LGG I+ L++ + + M+ S +SL+ + V C + GIN Y
Sbjct: 484 VGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPS 543
Query: 495 L----GNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNCSC 549
L NLT CN C C Y +CG D I YF+PC AGC S + Y C+C
Sbjct: 544 LTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTC 603
Query: 550 IK-EGLITADAEGDFIDAR---------------PGKCDAKCYKLPLFIAFIF 586
++ +IT G R GKC C L F+ F+F
Sbjct: 604 VQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLF 656
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 214 bits (546), Expect = 2e-55
Identities = 158/611 (25%), Positives = 281/611 (45%), Gaps = 56/611 (9%)
Query: 104 NIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIA 163
NI+ F++ +L +CQ + S+ +K + L + + +IS+ ++ IF++
Sbjct: 30 NIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVS 89
Query: 164 FYGDRKKVIWFVASSFLIGLGSLLCA-------FPSINEENKQSKVGIE--------DIC 208
++G R V LIG+G L A P E Q + ++C
Sbjct: 90 YFGSR------VHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQAELC 143
Query: 209 E---EIKVVSGCQSSGISFQSKYLSFF---ILGQTVQGIAGMPLYILGITFIDENVATHS 262
+ + S C S+ + Q + S + ++ Q + GI +P+ GI+++D+ +
Sbjct: 144 QKHWQDLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSN 203
Query: 263 AGIYLGIAECTSMIGYALGYVLGAPLVKVPENTTSATNTTVN--NGSPEWLWTWWINFLF 320
+ +Y+ I S+ G A GY+LG+ ++++ + VN G P W+ WW+ L
Sbjct: 204 SPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLI 263
Query: 321 AAVVAWCTLIPLSCFPNNMP-GSTRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWIL 379
++ + T P FP MP G+ R A + +++ + + + C L +L
Sbjct: 264 SSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAKSRGSLVDFIKRFPCIFLRLL 323
Query: 380 MKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLL 439
M N + + + L++ T VI G S FL +LE Q+ + A L G V +P ALG L
Sbjct: 324 M-NSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGMLF 382
Query: 440 GGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLGNLT 499
GG+++ S +A+ R IS+IL V + F+ C+ A + + + +
Sbjct: 383 GGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPP-STSSSIHPQS 441
Query: 500 APCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCT---YSKAQNQKKMYYNCSCIKEGLIT 556
C C C SI+ +CG + IEY SPC AGC+ S A +++ +Y NCSC+
Sbjct: 442 PACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCV------ 495
Query: 557 ADAEGDFIDARPGKCDAKC--YKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSL 614
G A+ G C C + LP F +LI + S P+ + + RVV + +S
Sbjct: 496 ---TGGSASAKTGSCPVPCAHFLLPAIFLISFVSLI-ACISHNPLYMMVLRVVNQEEKSF 551
Query: 615 ALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNK---------TKM 665
A+GV ++++R+ +P P+++ ++ + SCI + G G C Y+ +M
Sbjct: 552 AIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALRDRYLGLQM 611
Query: 666 AFLLVGICFLC 676
+ +G+ LC
Sbjct: 612 GYKALGMLLLC 622
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 213 bits (541), Expect = 7e-55
Identities = 154/637 (24%), Positives = 275/637 (43%), Gaps = 54/637 (8%)
Query: 102 CNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIF 161
CN + F+ I + + ++ +SI ++ + + + ++ S++I + LV +F
Sbjct: 24 CNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVF 83
Query: 162 IAFYGD---RKKVIWFVASSFLIGLGSLLCAFPS-------------IN-EENKQSKVGI 204
++++G R K+I L+G GS+L + P IN EN S +
Sbjct: 84 VSYFGSKLHRPKLIGI--GCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLST 141
Query: 205 EDICEEIK--------VVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDE 256
I + + V C S Y+ +G ++GI P+ LGI++ID+
Sbjct: 142 CLINQTLSFNGTSPEIVEKDCVKESGSHMWIYV---FMGNMLRGIGETPIVPLGISYIDD 198
Query: 257 NVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTW 314
+ +YLG MIG +G+ LG+ K V + + W+ W
Sbjct: 199 FAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAW 258
Query: 315 WINFLFAAVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFF---DSRLKDLKLGT---- 367
W+ FL + + + + IP P N P + + + LH D R + L
Sbjct: 259 WLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKISLSLHVLKTNDDRNQTANLTNQGKN 317
Query: 368 ---NIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTL 424
N+ +L ++ NP+ + L + IG+ ++ Y+E Q+ + + A L
Sbjct: 318 VTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFL 377
Query: 425 AGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAG 484
G++ IP A G LGG I+ ++S + +F +TS+IS + + + C AG
Sbjct: 378 LGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAG 437
Query: 485 INEDYDGTGKL-GNLTAP---CNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ 540
+ YDG + ++ P CN +C C S + +CG + I Y SPC AGC S +
Sbjct: 438 LTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKK 497
Query: 541 KKMYYNCSCIKEGLITADAEGDFIDARPGKC--DAKC-YKLPLFIAFIFSTLIFSGFSGV 597
++YNCSC++ + A G+C D C K +++A +FS G
Sbjct: 498 HTVFYNCSCVE----VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGT 553
Query: 598 PIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRC 657
+L ++V +L++LA+G +++R G I P F + +C+ N CG G C
Sbjct: 554 TFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGAC 613
Query: 658 WIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRR 694
IYN + +G+ + ++ + F K++
Sbjct: 614 RIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKK 650
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 201 bits (510), Expect = 3e-51
Identities = 154/648 (23%), Positives = 281/648 (43%), Gaps = 67/648 (10%)
Query: 103 NNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFI 162
+NI+ F++ + +L + Q ++ G + SI +K + L + L ++ + + +F+
Sbjct: 24 HNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFV 83
Query: 163 AFYGDR---KKVIWFVASSFLIGLGSLLCAFPS-INEENKQSKVGIEDICEEIKVV---- 214
+++G R ++I + A L+ L LL P I+E + ED+ ++ K
Sbjct: 84 SYFGSRVHRPRMIGYGA--ILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLP 141
Query: 215 -----------SGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSA 263
C S + + + QT+ G+ G+P+ GI++ID+ ++
Sbjct: 142 TTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNS 201
Query: 264 GIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFA 321
+YLGI +M+G L + LG+ +++ V N ++ P W+ WW+ FL A
Sbjct: 202 PLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIA 261
Query: 322 AVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRLKD------------------- 362
A IP FP MP R +RK L DS +
Sbjct: 262 AGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDG 321
Query: 363 -LKLGTN------IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFI 415
+++ N IK L +++P+ + + LS+ + G + FLP +LE QF
Sbjct: 322 LVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFS 381
Query: 416 LTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFV 475
+T + A L G + P +G ++GGV+V L + ++ ++ L + + F+
Sbjct: 382 ITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFI 441
Query: 476 RCNPVQFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDD-IEYFSPCFAGCTY 534
C+ Q AGI L L+ C E C C ++ +C +EY +PC AGC+
Sbjct: 442 GCSSHQIAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSS 500
Query: 535 SKAQ----NQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPL-FIAFIFSTL 589
Q N + Y NCSC+ EG G CD+ C L + F+ +
Sbjct: 501 WVVQDALDNSQVFYTNCSCVVEG----------NPVLAGSCDSTCSHLVVPFLLLVSLGS 550
Query: 590 IFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVN 649
+ + P + + R V + ++LA+G+ ++ LRI +P P I + +T+C+ ++
Sbjct: 551 ALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS 610
Query: 650 KCGHTGRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNE 697
CG C YN + +G+ F K ++I + + +++ E
Sbjct: 611 -CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKE 657
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 201 bits (510), Expect = 3e-51
Identities = 154/648 (23%), Positives = 281/648 (43%), Gaps = 67/648 (10%)
Query: 103 NNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFI 162
+NI+ F++ + +L + Q ++ G + SI +K + L + L ++ + + +F+
Sbjct: 46 HNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFV 105
Query: 163 AFYGDR---KKVIWFVASSFLIGLGSLLCAFPS-INEENKQSKVGIEDICEEIKVV---- 214
+++G R ++I + A L+ L LL P I+E + ED+ ++ K
Sbjct: 106 SYFGSRVHRPRMIGYGA--ILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLP 163
Query: 215 -----------SGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSA 263
C S + + + QT+ G+ G+P+ GI++ID+ ++
Sbjct: 164 TTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNS 223
Query: 264 GIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFA 321
+YLGI +M+G L + LG+ +++ V N ++ P W+ WW+ FL A
Sbjct: 224 PLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIA 283
Query: 322 AVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRLKD------------------- 362
A IP FP MP R +RK L DS +
Sbjct: 284 AGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDG 343
Query: 363 -LKLGTN------IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFI 415
+++ N IK L +++P+ + + LS+ + G + FLP +LE QF
Sbjct: 344 LVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFS 403
Query: 416 LTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFV 475
+T + A L G + P +G ++GGV+V L + ++ ++ L + + F+
Sbjct: 404 ITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFI 463
Query: 476 RCNPVQFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDD-IEYFSPCFAGCTY 534
C+ Q AGI L L+ C E C C ++ +C +EY +PC AGC+
Sbjct: 464 GCSSHQIAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSS 522
Query: 535 SKAQ----NQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPL-FIAFIFSTL 589
Q N + Y NCSC+ EG G CD+ C L + F+ +
Sbjct: 523 WVVQDALDNSQVFYTNCSCVVEG----------NPVLAGSCDSTCSHLVVPFLLLVSLGS 572
Query: 590 IFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVN 649
+ + P + + R V + ++LA+G+ ++ LRI +P P I + +T+C+ ++
Sbjct: 573 ALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS 632
Query: 650 KCGHTGRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNE 697
CG C YN + +G+ F K ++I + + +++ E
Sbjct: 633 -CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKE 679
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 198 bits (503), Expect = 2e-50
Identities = 124/507 (24%), Positives = 230/507 (45%), Gaps = 27/507 (5%)
Query: 185 SLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGM 244
S L P + E + Q V + + + K+ + C+ + S + LG ++GI
Sbjct: 29 STLSISPCLLESSSQLPVSVMEKSKS-KISNECE---VDTSSSMWIYVFLGNLLRGIGET 84
Query: 245 PLYILGITFIDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTT 302
P+ LGI ++D+ + +A Y+G + ++IG G++LG+ K V + + T
Sbjct: 85 PIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHIT 144
Query: 303 VNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIK---ARKRKQLHFFDSR 359
+ P+W+ WW+ +L A +++ +P P ++P S + + K D
Sbjct: 145 ITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDH 204
Query: 360 L-------KDLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLEN 412
++ K+ +D +L L NPV + ++ + G + P Y+E
Sbjct: 205 TDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQ 264
Query: 413 QFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFI 472
Q+ + + A + GL+ IP ALG GG+++ +S + + +SV +L + +
Sbjct: 265 QYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSL 324
Query: 473 IFVRCNPVQFAGINEDYDGTGKLGN----LTAPCNEKCRCSSSIYSSICGRDDIEYFSPC 528
+ C AG+ Y GT + L + CN +C+CS + + +CG + I Y S C
Sbjct: 325 FALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSAC 384
Query: 529 FAGCTYSKAQNQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFST 588
AGC S + ++YNC+C+ I A G+ G+C +F+ F+ +
Sbjct: 385 LAGCQTSNRSGKNIIFYNCTCVG---IAASKSGN-SSGIVGRCQKDNGCPQMFLYFLVIS 440
Query: 589 LIFS---GFSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCIL 645
+I S G+P + + R + +L+S ALG+ + +R+ IP P F + +TSC+
Sbjct: 441 VITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLK 500
Query: 646 RDVNKCGHTGRCWIYNKTKMAFLLVGI 672
+CG G C +Y+ + + I
Sbjct: 501 WGFKRCGSRGSCRLYDSNVFRYQIKSI 527
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 194 bits (494), Expect = 2e-49
Identities = 138/615 (22%), Positives = 270/615 (43%), Gaps = 57/615 (9%)
Query: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
CC ++ F+ + + + G + +I ++ + + + ++ S++I + LV
Sbjct: 38 CCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVIT 97
Query: 161 FIAFYG---DRKKVIWFVASSFLIGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGC 217
F++++G R K+I A ++G+G+LL A P E+ K
Sbjct: 98 FVSYFGAKLHRPKIIG--AGCVIMGVGTLLIAMPQF-------------FMEQYKYERYS 142
Query: 218 QSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIG 277
SS + +S +L + Q L ++ ++++ + I G + ++IG
Sbjct: 143 PSSNSTLS---ISPCLLESSSQ---------LPVSVMEKS----KSKISNGCVQTVAIIG 186
Query: 278 YALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCF 335
G++LG+ K V + + T+ P+W+ WW+ +L A +++ +P
Sbjct: 187 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 246
Query: 336 PNNMPGSTRIK---ARKRKQLHFFDSRL-------KDLKLGTNIKDLCAALWILMKNPVL 385
P ++P S + + K D ++ K+ +D +L L NPV
Sbjct: 247 PKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVY 306
Query: 386 ICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVS 445
+ ++ + G + P Y+E Q+ + + A + GL+ IP ALG GG+++
Sbjct: 307 FLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMK 366
Query: 446 TLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLGN----LTAP 501
+S + + +SV +L + + + C AG+ Y GT + L +
Sbjct: 367 KFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSD 426
Query: 502 CNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKEGLITADAEG 561
CN +C+CS + + +CG + I Y S C AGC S + ++YNC+C+ I A G
Sbjct: 427 CNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVG---IAASKSG 483
Query: 562 DFIDARPGKCDAKCYKLPLFIAFIFSTLIFS---GFSGVPIVLAMTRVVPDKLRSLALGV 618
+ G+C +F+ F+ ++I S G+P + + R + +L+S ALG+
Sbjct: 484 NS-SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGI 542
Query: 619 SYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGICFLCKL 678
+ +R+ IP P F + +TSC+ +CG G C +Y+ + +G+ +
Sbjct: 543 YTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGT 602
Query: 679 CTIIFTTIAFFIYKR 693
+I+ + FI K+
Sbjct: 603 VSILLSIAVLFILKK 617
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 191 bits (486), Expect = 2e-48
Identities = 135/596 (22%), Positives = 261/596 (43%), Gaps = 30/596 (5%)
Query: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
C + ++ F++ + + + ++ + ++++ + T + S++I + L+ I
Sbjct: 15 CLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74
Query: 161 FIAFYGDR-KKVIWFVASSFLIGLGSLLCAFPS--INEENKQSKVGIED-------ICEE 210
F++++G + + I ++GLG L + P +N+ +S V + +C E
Sbjct: 75 FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCME 134
Query: 211 -----IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGI 265
++ +S + ++G V+G+ P+ LGI++I++ ++ +
Sbjct: 135 NGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPL 194
Query: 266 YLGIAECTSMIGYALGYVLGAPLVKVPENT--TSATNTTVNNGSPEWLWTWWINFLFAAV 323
Y+G+ E ++IG +G +L + V +T + + + W+ WW FL A
Sbjct: 195 YIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAG 254
Query: 324 VAWCTLIPLSCFPNNMPGS---TRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWILM 380
V T IP PN +P T K + +K K G KD + L
Sbjct: 255 VNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGIT-KDFLPFMKSLS 313
Query: 381 KNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLG 440
NP+ + L ++ + F+P YLE Q+ ++ + A L G+ +P +G ++G
Sbjct: 314 CNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIG 373
Query: 441 GVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK----LG 496
G+I+ +++ K S++ +L + C GIN Y+G +
Sbjct: 374 GLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVEN 433
Query: 497 NLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKEGLIT 556
++ A CN C C S I+ +CG + + Y S C AGC S ++ NCSCI+ +
Sbjct: 434 DIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSGNS 493
Query: 557 ADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLAL 616
+ G D P D I S+ I+S + +P + + R + + +SL +
Sbjct: 494 SAVLG-LCDKGP---DCSLMLQYFLILSAMSSFIYS-LAAIPGYMVLLRCMKSEEKSLGV 548
Query: 617 GVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGI 672
G+ R+F IP P F +++C+ KCG +G C IY+ T ++ +G+
Sbjct: 549 GLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 191 bits (486), Expect = 2e-48
Identities = 135/596 (22%), Positives = 261/596 (43%), Gaps = 30/596 (5%)
Query: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
C + ++ F++ + + + ++ + ++++ + T + S++I + L+ I
Sbjct: 15 CLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74
Query: 161 FIAFYGDR-KKVIWFVASSFLIGLGSLLCAFPS--INEENKQSKVGIED-------ICEE 210
F++++G + + I ++GLG L + P +N+ +S V + +C E
Sbjct: 75 FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCME 134
Query: 211 -----IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGI 265
++ +S + ++G V+G+ P+ LGI++I++ ++ +
Sbjct: 135 NGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPL 194
Query: 266 YLGIAECTSMIGYALGYVLGAPLVKVPENT--TSATNTTVNNGSPEWLWTWWINFLFAAV 323
Y+G+ E ++IG +G +L + V +T + + + W+ WW FL A
Sbjct: 195 YIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAG 254
Query: 324 VAWCTLIPLSCFPNNMPGS---TRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWILM 380
V T IP PN +P T K + +K K G KD + L
Sbjct: 255 VNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGIT-KDFLPFMKSLS 313
Query: 381 KNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLG 440
NP+ + L ++ + F+P YLE Q+ ++ + A L G+ +P +G ++G
Sbjct: 314 CNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIG 373
Query: 441 GVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK----LG 496
G+I+ +++ K S++ +L + C GIN Y+G +
Sbjct: 374 GLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVEN 433
Query: 497 NLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKEGLIT 556
++ A CN C C S I+ +CG + + Y S C AGC S ++ NCSCI+ +
Sbjct: 434 DIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSGNS 493
Query: 557 ADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLAL 616
+ G D P D I S+ I+S + +P + + R + + +SL +
Sbjct: 494 SAVLG-LCDKGP---DCSLMLQYFLILSAMSSFIYS-LAAIPGYMVLLRCMKSEEKSLGV 548
Query: 617 GVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGI 672
G+ R+F IP P F +++C+ KCG +G C IY+ T ++ +G+
Sbjct: 549 GLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 187 bits (475), Expect = 3e-47
Identities = 145/612 (23%), Positives = 261/612 (42%), Gaps = 56/612 (9%)
Query: 128 VSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAFYGD---RKKVIWFVASSFLIGLG 184
+S ++ +++ + ++ S++I + V +F++++G R K+I FL+G G
Sbjct: 3 ISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGI--GCFLMGTG 60
Query: 185 SLLCAFPSI--------------NEENKQSKV---------GIEDICEEIKVVSGCQSSG 221
S+L A P EN S + + EI + GC
Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEI-IERGCVKES 119
Query: 222 ISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIGYALG 281
S Y+ +G ++GI P+ LGI++ID+ + +YLG M G
Sbjct: 120 GSHMWIYV---FMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFA 176
Query: 282 YVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFP--N 337
++LG+ K V + + W+ WW+ FL + +V+ + IP P
Sbjct: 177 FMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNP 236
Query: 338 NMPGSTR--------IKAR-KRKQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICL 388
N P R +K KR Q+ +R K + N+ +L ++ NP+ +
Sbjct: 237 NKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYIT--KNVTGFFQSLKSILTNPLYVIF 294
Query: 389 ALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTLE 448
+ I + ++ +E Q+ + + L G++ +P A+G GG I+ +
Sbjct: 295 VIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFK 354
Query: 449 MSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKL-GNLTAP---CNE 504
+S L + ++ + L+ V F+ C AG+ YDG + ++ P CN
Sbjct: 355 LSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNS 414
Query: 505 KCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKE-GLITADAEGDF 563
+C C S + +CG + I Y SPC AGC S + ++YNCSC++ GL +
Sbjct: 415 ECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHL 474
Query: 564 IDA-RPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVI 622
+ R C K Y + I + + L G + ++ + R+V +L++LA+G +I
Sbjct: 475 GECPRDDACTRKSY-VYFVIQVLDAFLCAVGLTSYSVL--VIRIVQPELKALAIGFHSMI 531
Query: 623 LRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGICFLCKLCTII 682
+R G I P F +T+C+ N CG G C IYN T + G+ ++
Sbjct: 532 MRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLV 591
Query: 683 FTTIAFFIYKRR 694
T+ F+ +++
Sbjct: 592 LLTVFIFVVRKK 603
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 176 bits (447), Expect = 5e-44
Identities = 128/515 (24%), Positives = 224/515 (43%), Gaps = 46/515 (8%)
Query: 217 CQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMI 276
C S + + + QT+ G+ G+P+ GI++ID+ ++ +YLGI +M+
Sbjct: 33 CSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMM 92
Query: 277 GYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSC 334
G L + LG+ +++ V N ++ P W+ WW+ FL AA IP
Sbjct: 93 GPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFF 152
Query: 335 FPNNMPGSTRIKARKRKQLHFFDSRLKD--------------------LKLGTN------ 368
FP MP R +RK L DS + +++ N
Sbjct: 153 FPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQF 212
Query: 369 IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLV 428
IK L +++P+ + + LS+ + G + FLP +LE QF +T + A L G +
Sbjct: 213 IKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCL 272
Query: 429 LIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINED 488
P +G ++GGV+V L + ++ ++ L + + F+ C+ Q AGI
Sbjct: 273 SFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQ 332
Query: 489 YDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDD-IEYFSPCFAGCTYSKAQ----NQKKM 543
L L+ C E C C ++ +C +EY +PC AGC+ Q N +
Sbjct: 333 TSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVF 391
Query: 544 YYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPL-FIAFIFSTLIFSGFSGVPIVLA 602
Y NCSC+ EG G CD+ C L + F+ + + + P +
Sbjct: 392 YTNCSCVVEG----------NPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFML 441
Query: 603 MTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNK 662
+ R V + ++LA+G+ ++ LRI +P P I + +T+C+ ++ CG C YN
Sbjct: 442 ILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNN 500
Query: 663 TKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNE 697
+ +G+ F K ++I + + +++ E
Sbjct: 501 DLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKE 535
>gi|28875799 cholecystokinin B receptor [Homo sapiens]
Length = 447
Score = 33.5 bits (75), Expect = 0.71
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 366 GTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLA 425
G ++L A+ I + V+ +++ +V++G S L + N F+L+ V+ L
Sbjct: 46 GAGTRELELAIRITLY-AVIFLMSVGGNMLIIVVLGLSRRLRT-VTNAFLLSLAVSDLLL 103
Query: 426 GLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVR----CNPVQ 481
+ +P L L+G I T + CKA+ + V+ +S + LV I R C P+Q
Sbjct: 104 AVACMPFTLLPNLMGTFIFGT--VICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQ 161
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 32.3 bits (72), Expect = 1.6
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Query: 496 GNLTAPCNE--KCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ 540
G L+ PCN KC+C + SIC R Y+ GC + N+
Sbjct: 297 GALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNR 343
>gi|4506971 solute carrier family 10, member 1 [Homo sapiens]
Length = 349
Score = 30.4 bits (67), Expect = 6.0
Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 13/183 (7%)
Query: 114 ILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLA-LEKSYDISSGLVAIF-IAFYGDRK-K 170
I L+ Q +G++ ++ K ++LK IE LA L L +F +A GD
Sbjct: 63 IALVAQ---YGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLS 119
Query: 171 VIWFVASSFL-IGLGSLLCAFPS--INEENKQSKVGIEDICEEIKVVSGCQSSGISFQSK 227
++ S+F +G+ LL S I + + + KV + I + +V + GI +SK
Sbjct: 120 IVMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSK 179
Query: 228 ---YLSFFILG-QTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIGYALGYV 283
Y+ + I G + + + + +L + +++ + + + IG+ LGYV
Sbjct: 180 RPQYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYV 239
Query: 284 LGA 286
L A
Sbjct: 240 LSA 242
>gi|100913198 six transmembrane epithelial antigen of the prostate 2
isoform b [Homo sapiens]
Length = 454
Score = 30.4 bits (67), Expect = 6.0
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 19/108 (17%)
Query: 342 STRIKARKR-----KQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICLALSKATEY 396
S I+AR++ +QL+F L L I++L L+ L + PV++ A+S AT +
Sbjct: 169 SNNIQARQQVIELARQLNFIPIDLGSLSSAREIENLPLRLFTLWRGPVVV--AISLATFF 226
Query: 397 LVIIGASEFLPIYLENQFI------------LTPTVATTLAGLVLIPG 432
+ + + Y NQ P VA TL LV + G
Sbjct: 227 FLYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAG 274
>gi|100913194 six transmembrane epithelial antigen of the prostate 2
isoform a [Homo sapiens]
Length = 490
Score = 30.4 bits (67), Expect = 6.0
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 19/108 (17%)
Query: 342 STRIKARKR-----KQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICLALSKATEY 396
S I+AR++ +QL+F L L I++L L+ L + PV++ A+S AT +
Sbjct: 169 SNNIQARQQVIELARQLNFIPIDLGSLSSAREIENLPLRLFTLWRGPVVV--AISLATFF 226
Query: 397 LVIIGASEFLPIYLENQFI------------LTPTVATTLAGLVLIPG 432
+ + + Y NQ P VA TL LV + G
Sbjct: 227 FLYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAG 274
>gi|100913196 six transmembrane epithelial antigen of the prostate 2
isoform a [Homo sapiens]
Length = 490
Score = 30.4 bits (67), Expect = 6.0
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 19/108 (17%)
Query: 342 STRIKARKR-----KQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICLALSKATEY 396
S I+AR++ +QL+F L L I++L L+ L + PV++ A+S AT +
Sbjct: 169 SNNIQARQQVIELARQLNFIPIDLGSLSSAREIENLPLRLFTLWRGPVVV--AISLATFF 226
Query: 397 LVIIGASEFLPIYLENQFI------------LTPTVATTLAGLVLIPG 432
+ + + Y NQ P VA TL LV + G
Sbjct: 227 FLYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAG 274
>gi|215272390 solute carrier family 18 (vesicular monoamine), member
1 isoform b [Homo sapiens]
Length = 493
Score = 30.0 bits (66), Expect = 7.8
Identities = 63/291 (21%), Positives = 111/291 (38%), Gaps = 55/291 (18%)
Query: 223 SFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVAT--HSAGIYLGIAECTSMIGYAL 280
+F Y F+ +T+QGI + G+ + +V T H G +G T++ G AL
Sbjct: 185 AFSGTYTLLFV-ARTLQGIGSSFSSVAGLGML-ASVYTDDHERGRAMG----TALGGLAL 238
Query: 281 GYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFPNNMP 340
G ++GAP S V +P + + L + C L P P +
Sbjct: 239 GLLVGAPF-------GSVMYEFVGKSAPFLILAFLA--LLDGALQLCILQPSKVSPESAK 289
Query: 341 GSTRIKARK------RKQLHFFDSRLKDLKLGTNI---------KDLCAALWILMKNPVL 385
G+ K L F + + L +GTN+ + LC+ + +L+ L
Sbjct: 290 GTPLFMLLKDPYILVAAGLAFLPASVSYL-IGTNLFGVLANKMGRWLCSLIGMLVVGTSL 348
Query: 386 ICLALSKATEYLVIIGA----------SEFLPIY-----LENQFILTPTVATTLAGLVLI 430
+C+ L+ L+ A S +PI L + + A +A +
Sbjct: 349 LCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYA--IADVAFC 406
Query: 431 PGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQ 481
G A+G GG IV + +++T VI+++ ++R P +
Sbjct: 407 MGFAIGPSTGGAIVKAI-----GFPWLMVITGVINIVYAPLCYYLRSPPAK 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.141 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,969,423
Number of Sequences: 37866
Number of extensions: 1203626
Number of successful extensions: 4015
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3865
Number of HSP's gapped (non-prelim): 34
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.