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Search of human proteins with 9256600
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9256600 protocadherin alpha subfamily C, 2 isoform 1
precursor [Homo sapiens]
(1007 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 2001 0.0
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 1690 0.0
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 895 0.0
gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precurs... 890 0.0
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 877 0.0
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 872 0.0
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 689 0.0
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 668 0.0
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 664 0.0
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 659 0.0
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs... 658 0.0
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 654 0.0
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 651 0.0
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 650 0.0
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 649 0.0
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs... 641 0.0
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 640 0.0
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 640 0.0
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs... 637 0.0
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 635 0.0
gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso... 629 e-180
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 628 e-180
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 627 e-179
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs... 626 e-179
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 623 e-178
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 622 e-178
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs... 622 e-178
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 621 e-178
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs... 621 e-178
gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precurs... 620 e-177
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 2001 bits (5185), Expect = 0.0
Identities = 1007/1007 (100%), Positives = 1007/1007 (100%)
Query: 1 MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60
MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN
Sbjct: 1 MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60
Query: 61 VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120
VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS
Sbjct: 61 VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120
Query: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180
LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN
Sbjct: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180
Query: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT
Sbjct: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
Query: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300
AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300
Query: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360
SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND
Sbjct: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360
Query: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420
NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT
Sbjct: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420
Query: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480
LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE
Sbjct: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480
Query: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540
NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE
Sbjct: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540
Query: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600
KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA
Sbjct: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600
Query: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660
GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV
Sbjct: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660
Query: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720
VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL
Sbjct: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720
Query: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780
LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE
Sbjct: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780
Query: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840
VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA
Sbjct: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840
Query: 841 GNLIILKNEAVSQNEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 900
GNLIILKNEAVSQNEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS
Sbjct: 841 GNLIILKNEAVSQNEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 900
Query: 901 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 960
SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP
Sbjct: 901 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 960
Query: 961 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007
TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 961 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 1690 bits (4377), Expect = 0.0
Identities = 857/858 (99%), Positives = 857/858 (99%)
Query: 1 MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60
MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN
Sbjct: 1 MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60
Query: 61 VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120
VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS
Sbjct: 61 VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120
Query: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180
LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN
Sbjct: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180
Query: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT
Sbjct: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
Query: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300
AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300
Query: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360
SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND
Sbjct: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360
Query: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420
NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT
Sbjct: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420
Query: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480
LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE
Sbjct: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480
Query: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540
NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE
Sbjct: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540
Query: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600
KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA
Sbjct: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600
Query: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660
GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV
Sbjct: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660
Query: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720
VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL
Sbjct: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720
Query: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780
LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE
Sbjct: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780
Query: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840
VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA
Sbjct: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840
Query: 841 GNLIILKNEAVSQNEPRQ 858
GNLIILKNEAVSQNE RQ
Sbjct: 841 GNLIILKNEAVSQNEVRQ 858
>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 895 bits (2313), Expect = 0.0
Identities = 496/990 (50%), Positives = 636/990 (64%), Gaps = 64/990 (6%)
Query: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
LLLLLLL + QL YSVPEE G VG +A+ LGLEL L P R+ S
Sbjct: 15 LLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV-----ASK 69
Query: 88 RY---LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144
R+ LE+ L +G LFVN RIDRE LC + C + LEV+ P+ V V+VE+ D+NDN
Sbjct: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129
Query: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204
P F + +L VSES P +RF +E A D DVGANSV TY LS ++F LD+ + +
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189
Query: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264
K++ELVLRK LDRE A HHL LTA DGG P +GT Q+ V VLD NDN+P F+QS Y V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
Query: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
++ E++ GT V+KLNASDPDEG+NG + YS +S FSID +TGE+ + G LD
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309
Query: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384
+E+ + Y+I + ATD+G PMAGHC VLV I+D NDN PE+ LT L PV E+A T++
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
Query: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443
A++SVND DSG N +V+ L +PF+L + F N Y+LV+ LDRERV+ Y + VTA D
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429
Query: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503
GG P L + +L VE++D+NDN P+F + Y+++++ENN PG + TV A D D +ENA
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
Query: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563
V+YSL+ER + ++SY+S+++ SG +YA+ D+E+ V A+D G PPL S V
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Query: 564 TANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622
T V+V+D ND+AP +L P AA ++VPR+ AG++V KV A+D+DSG NAWL Y
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 623 HL--AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAV 680
L A +S F+V L+TGEI TTR + + L V+V+D+GEP+L+A+ + V++
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
Query: 681 VD--RVSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAY 737
V+ + K V P ++ +YLIIA+ VS + +LT+++ + ++C
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729
Query: 738 GTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACL 797
G G R P + A G+ S ++ + C
Sbjct: 730 G--------GCRAGKPTLVCSSA---------------------VGSWSYSQQQPQRVCS 760
Query: 798 TAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPR 857
G M ++ P V + ++L G +PR
Sbjct: 761 GEGPPKTDLMAFSPCLP----PDLGSVDVGEEQDLNVDHGL----------------KPR 800
Query: 858 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 917
QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA
Sbjct: 801 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 860
Query: 918 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 977
GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE
Sbjct: 861 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 920
Query: 978 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007
ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 921 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precursor
[Homo sapiens]
Length = 963
Score = 890 bits (2300), Expect = 0.0
Identities = 481/984 (48%), Positives = 641/984 (65%), Gaps = 34/984 (3%)
Query: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
+L L + G AA QL YSVPEE G VGN++ L L + R L + Y
Sbjct: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRF--LSSHRELY 65
Query: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
+DL SG L V E DRE LC + C+L+ +++ +P+ + + + +LD NDNSP FP
Sbjct: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125
Query: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
+ QL + E + PGARF + +AQD D G+N + +Y LSPS+HF LD+ + S+ EL
Sbjct: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185
Query: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
VL K LDREQ A H LVLTA DGG+PARSG AQ+++ V+DTNDN+P F++S YR ++ E
Sbjct: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245
Query: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
+P GT++ ++ A DPDEGSNGE++YSLS+ T R F + +GEV+V L E +
Sbjct: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPE-T 304
Query: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
+ Y++A D G +A K+LV++ DVND+APE+ L +PVPE+A P T++A+ SV
Sbjct: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364
Query: 390 NDQDSGPNRKVSLGLEATLPFRLNG-FGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
D+D N +V G+ + PF+L F N Y+L++ GPLDRE+++ Y + +TA+D G P
Sbjct: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424
Query: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
L++ RT+ V ++D+NDN P+F + +++ ENN PG L V A DPD +N V+Y L
Sbjct: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484
Query: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
L+ +G +S +++ S+SG++ A SFD+E+ R F VE +D G PP S+TVT N++
Sbjct: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544
Query: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
VVD ND+ P IL+P N S E+VPR+A G+LVTKV+A D+DSG NAWL YH+++ S
Sbjct: 545 VVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRAS 604
Query: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
D LF++ + GE+RT R + + VVVRD+G+P LS+SV + V + + V ++L
Sbjct: 605 DSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLL 664
Query: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFCGV 748
PD + + S LYL+IAL+ +SF+FL ++ K ++ CC C
Sbjct: 665 PDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ----SPGCCAQSCC- 719
Query: 749 RERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFMF 808
RS +L +++ + I+V L++TY Y+A L GS +++ +
Sbjct: 720 --RSTEDL------RYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLL 771
Query: 809 YNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAG-NLIILKNE----AVSQNEPRQPNPDW 863
+ D RNL G N + I ++N A PRQPNPDW
Sbjct: 772 RG------------EYNAADLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDW 819
Query: 864 RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNS 923
RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNS
Sbjct: 820 RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNS 879
Query: 924 WTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKK 983
WTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKK
Sbjct: 880 WTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKK 939
Query: 984 KKKKGNKTQEKKEKGNSTTDNSDQ 1007
KKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 940 KKKKGNKTQEKKEKGNSTTDNSDQ 963
>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 877 bits (2267), Expect = 0.0
Identities = 488/987 (49%), Positives = 636/987 (64%), Gaps = 58/987 (5%)
Query: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
LL LLLL + QL YS+PEE G VG VA+ LGLEL L P R+
Sbjct: 15 LLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRV--ASKTHR 72
Query: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
LE++L +G LFVN RIDRE LC+ C + LE++A P+ V VEV++ DINDN P
Sbjct: 73 DLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVKDINDNPPV 132
Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
F + + ES +RF IE A D D+GAN++ TY LSPS++F LD++ E SK L
Sbjct: 133 FRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSL 192
Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
L LRK LDRE+ HL+LTA DGG P GT ++ + VLD NDN+P FDQ+ YRV L
Sbjct: 193 WLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLL 252
Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
E + GTLV LNASD DEG NGE+ +S S S ++ F +D+S+GE+R+I LDYEE
Sbjct: 253 ETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEE 312
Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
SY+I V+A D+G PM+ HCKVLV ++DVNDNAPE+ +T LY P+ E+A +T++A++
Sbjct: 313 TKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVIALI 372
Query: 388 SVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGI 446
+V+D+DSG N +V+ L +PF+L + F N Y+LV+ LDRE ++VY + VTA DGG
Sbjct: 373 TVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARDGGS 432
Query: 447 PQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTY 506
P L + + VE++D+NDN P+F + Y+++++ENN PG + TV A D D +ENA V+Y
Sbjct: 433 PSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSY 492
Query: 507 SLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTAN 566
SL+ER + +++YVS+++ SG +YA+ D+E+ V A+D G PPL S VT
Sbjct: 493 SLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQ 552
Query: 567 VYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL- 624
V+V+D ND+AP +L P A E+VPR AG++V KV A+D+DSG NAWL Y L
Sbjct: 553 VFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYNAWLSYELQ 612
Query: 625 -AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD- 682
A F+V L+TGEI TTR + + S + L V+V+D+GEP+L+A+ + V++V+
Sbjct: 613 PAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATATVLVSLVES 672
Query: 683 -RVSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTA 740
+ K V P ++ +YLIIA+ VS + +LT+++ + ++C G
Sbjct: 673 GQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSVPPTEGAY 732
Query: 741 CCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAG 800
G P + A G+ S ++ + C + G
Sbjct: 733 VPG--------KPTLVCSSA---------------------LGSWSNSQQRRQRVCSSEG 763
Query: 801 SGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPN 860
M ++ G ++ S N + ++ Q NL + N PRQPN
Sbjct: 764 PPKTDLMAFSPG-------------LSPSLNTSERNEQPEANLDLSGN-------PRQPN 803
Query: 861 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN 920
PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN
Sbjct: 804 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN 863
Query: 921 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 980
SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK
Sbjct: 864 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 923
Query: 981 KKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007
KKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 924 KKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
Length = 948
Score = 872 bits (2252), Expect = 0.0
Identities = 484/990 (48%), Positives = 635/990 (64%), Gaps = 66/990 (6%)
Query: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
LL LLLL + QLRYSVPEE G VG +A+ LGLEL L P R+ S
Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV-----ASK 69
Query: 88 RY---LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144
R+ LE++L +G LFVN RIDRE LC + C + +EV+ P+ V VEVE+ DINDN
Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
Query: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204
P FP ++ ES +RF +E A D D+G N++ +Y+LS SE F LD++ E S
Sbjct: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
Query: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264
+ L LVL K LDRE+ A +L+L A DGG P +GT QI ++VLD NDN P F QS Y+V
Sbjct: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
Query: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
+L E++ GTLVVKLNASD DEG N E+ YSL S S + F+ID +GE+R G LD
Sbjct: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
Query: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384
YEEA SY+I V ATD+G M+GHCK+ + +VD+NDN PEV +T L P+ ENA+ T++
Sbjct: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
Query: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443
A+++V+D+DSG N V+ L +PF+L + F N Y+LV+ LDRE V+ Y + VTA D
Sbjct: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
Query: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503
GG P L + ++ +E++D+NDN P+F + Y+++++ENN PG + TV A D D +ENA
Sbjct: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
Query: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563
V+YSL+ER + ++SYVS+++ SG +YA+ D+E+ V A+D G PPL S V
Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549
Query: 564 TANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622
T V+V+D ND+AP +L P T + A E+VP + AG++V KV A+D+DSG NAWL Y
Sbjct: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 623 --HLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAV 680
L S F+V L+TGEI TTR + + L V+V+D+GEP+L+A+ + V++
Sbjct: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
Query: 681 VDRVSKILPDTQRHV---KSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAY 737
V+ ++ V S T ++ +YLIIA+ VS + +LT+++ + ++C
Sbjct: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729
Query: 738 GTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACL 797
G R+P + ++ + G+ S ++ + C
Sbjct: 730 GA-----------RAPGKPTLVCSSAV------------------GSWSYSQQRRQRVCS 760
Query: 798 TAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPR 857
M ++ GP S + +++S + +PR
Sbjct: 761 GEDPPKTDLMAFSPSLSQGP-DSAEEKQLSESEYV---------------------GKPR 798
Query: 858 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 917
QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA
Sbjct: 799 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 858
Query: 918 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 977
GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE
Sbjct: 859 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 918
Query: 978 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007
ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 919 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 689 bits (1777), Expect = 0.0
Identities = 396/967 (40%), Positives = 576/967 (59%), Gaps = 46/967 (4%)
Query: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
+L +L L G + QLRYSV EE PG LVGNVA+ LGL++ L L++ +
Sbjct: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72
Query: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
RY L L SGAL VN++IDRE+LC CLL ++V+ +P+ + VEVEILD+NDNSP
Sbjct: 73 RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
F P ++++SES A GARF ++SAQDPDVG N+V Y LSP+ HF L++K L++
Sbjct: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
ELVL + LDRE A H LVLTAVDGG PARSGT ISV VLD NDN+P F S RV +
Sbjct: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
E++P GTL+++LNA+DPDEG+NG+L YS +TS+ R LF +D S+G + V+G +D+EE
Sbjct: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
+ Y+I+ +A D+G M GHC + VD+ DVNDNAPEV+L L +PV E+ T+V +
Sbjct: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
Query: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447
+V D+DSG N +VSL + LPF++ N Y+L+ S PLDRE + Y I + A+D G P
Sbjct: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432
Query: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507
L T+++ ISD+NDN P F + Y+ YI EN PG LLCTV A+DPD +NA +TYS
Sbjct: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492
Query: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567
++ ++QG P +S+V +N G ++A +FDYE + + V +D GSPPL + + +V
Sbjct: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552
Query: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626
+V+D ND+AP +L+P +A + +PR+AP G LVTKV A+D+D+G NAWL Y L Q
Sbjct: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
Query: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686
++ LF V HTGE+RT R + ++ T + V+VRDNG+PSLS++ + + + D +
Sbjct: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
Query: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746
+P + + P S++TLYLI+AL+TVS + L+T LS KC + A G GG C
Sbjct: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730
Query: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805
R+ SP+ + YKQ++ N+ LK ++EV + ++++CY+ C + S
Sbjct: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786
Query: 806 FMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPDWRY 865
F F + P + SR+ N +++ PN DWR+
Sbjct: 787 FTFLRPLSVQQPTALALEPDAIRSRS----------------NTLRERSQQAPPNTDWRF 830
Query: 866 SASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAG 918
S + R G S + ++ G P+ Q+ T ++SA+ EA + S +G G
Sbjct: 831 SQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGG 881
Query: 919 VNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEE 978
+ + +YGP Q P + IPGS A ++ + K+ G K++
Sbjct: 882 AGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKK 937
Query: 979 TKKKKKK 985
+ KK+KK
Sbjct: 938 SGKKEKK 944
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 668 bits (1723), Expect = 0.0
Identities = 412/984 (41%), Positives = 580/984 (58%), Gaps = 69/984 (7%)
Query: 15 RLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP 74
RL R L+LL +LL L +Q+RYSVPEE G+ VG+++R LGLE R L
Sbjct: 5 RLHRDYKGLVLLGILLGTLW---ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAE 61
Query: 75 GCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAV 134
+RI G + L+ SG+L RIDRE LC +C L+L++L + V + V
Sbjct: 62 RGVRIIPRGRT--QLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGV 119
Query: 135 EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFE 194
EVE+ DINDN+P F ++++SE+ A RF + A DPD+G NS+Q+YELSP+ HF
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFS 179
Query: 195 LDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNS 254
L ++ + SK ELVL++ LDRE+ A HHLVLTA DGG P R+GTA+I V VLD NDN+
Sbjct: 180 LIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNA 239
Query: 255 PAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDAST 314
PAF Q YR + E+ GT ++ +NA+DPDEG N E+RYS Y D+ Q+F +D ++
Sbjct: 240 PAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNS 298
Query: 315 GEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPV 374
G + IG LD+EE+ YQ+ VQA D + KVL+ ++DVNDNAPEVVLT L S V
Sbjct: 299 GTISTIGELDHEESGFYQMEVQAMDN--AGYSARAKVLITVLDVNDNAPEVVLTSLASSV 356
Query: 375 PENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVA 433
PEN+ T++A+L+VNDQDS N +V ++ LPF+L +GN Y+LV LDRE+V
Sbjct: 357 PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVP 416
Query: 434 VYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQA 493
YNITVTATD G P L++ + + ++D NDNPP F + SYS YI ENN GV L +V A
Sbjct: 417 SYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTA 476
Query: 494 TDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQD 553
DPD +ENA++TYSL E IQG ++SYVSINS +G LYA++SFDYE+FR+ V V A+D
Sbjct: 477 HDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARD 536
Query: 554 KGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDS 612
G PPLSS V+ +++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D
Sbjct: 537 NGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDR 596
Query: 613 DSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSA 672
DSGQNAWL Y L + S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA
Sbjct: 597 DSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 656
Query: 673 SVAITVAVVDRVSKILPDTQRHVKSPRT--YSEITLYLIIALSTVSFIFLLTIIILSIIK 730
+V +TVAV D + ++L D ++SP S++TLYL++A++ VS +FL +I+L ++
Sbjct: 657 TVTLTVAVADSIPQVLADL-GSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALR 715
Query: 731 CYRY--TAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLT 788
R+ + A GG G +PA HF+ V G +
Sbjct: 716 LRRWHKSRLLQASGGGLTG----APAS---------------------HFVGVDGVQAFL 750
Query: 789 KTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKN 848
+TY ++ LT S +F P P+ A V+ + +G+ + K
Sbjct: 751 QTYSHEVSLTTDSRKSHLIF--------PQPNYADMLVSQESFEKSEPLLLSGDSVFSK- 801
Query: 849 EAVSQNEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSS 901
++ E PN DWR+S + R G S + ++ G P+ Q+ T ++S
Sbjct: 802 DSHGLIEQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILAS 855
Query: 902 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT 961
A+ EA + S +G G + + +YGP Q P + IPGS A ++
Sbjct: 856 AS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAA 908
Query: 962 NSQIDKSDFITFGKKEETKKKKKK 985
+ K+ G K+++ KK+KK
Sbjct: 909 GKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
[Homo sapiens]
Length = 878
Score = 664 bits (1712), Expect = 0.0
Identities = 355/783 (45%), Positives = 505/783 (64%), Gaps = 10/783 (1%)
Query: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
+L +L L G + QLRYSV EE PG LVGNVA+ LGL++ L L++ +
Sbjct: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72
Query: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
RY L L SGAL VN++IDRE+LC CLL ++V+ +P+ + VEVEILD+NDNSP
Sbjct: 73 RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
F P ++++SES A GARF ++SAQDPDVG N+V Y LSP+ HF L++K L++
Sbjct: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
ELVL + LDRE A H LVLTAVDGG PARSGT ISV VLD NDN+P F S RV +
Sbjct: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
E++P GTL+++LNA+DPDEG+NG+L YS +TS+ R LF +D S+G + V+G +D+EE
Sbjct: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
+ Y+I+ +A D+G M GHC + VD+ DVNDNAPEV+L L +PV E+ T+V +
Sbjct: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
Query: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447
+V D+DSG N +VSL + LPF++ N Y+L+ S PLDRE + Y I + A+D G P
Sbjct: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432
Query: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507
L T+++ ISD+NDN P F + Y+ YI EN PG LLCTV A+DPD +NA +TYS
Sbjct: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492
Query: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567
++ ++QG P +S+V +N G ++A +FDYE + + V +D GSPPL + + +V
Sbjct: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552
Query: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626
+V+D ND+AP +L+P +A + +PR+AP G LVTKV A+D+D+G NAWL Y L Q
Sbjct: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
Query: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686
++ LF V HTGE+RT R + ++ T + V+VRDNG+PSLS++ + + + D +
Sbjct: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
Query: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746
+P + + P S++TLYLI+AL+TVS + L+T LS KC + A G GG C
Sbjct: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730
Query: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805
R+ SP+ + YKQ++ N+ LK ++EV + ++++CY+ C + S
Sbjct: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786
Query: 806 FMF 808
F F
Sbjct: 787 FTF 789
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 659 bits (1700), Expect = 0.0
Identities = 398/1037 (38%), Positives = 588/1037 (56%), Gaps = 94/1037 (9%)
Query: 25 LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83
++ LLL LL + SQL Y+V EEQ G VGN+A LGL++ +L G + +
Sbjct: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
Query: 84 APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143
P YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV NP+ + VE+E+LDIND
Sbjct: 61 TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117
Query: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203
N P FP P+ +++SES PG RF +ESA DPDVG NS++ YE++P+ +F LD++ +
Sbjct: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177
Query: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244
++ ELVL K LDREQ A+H VLTAVDGG +P R+GTA ++
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
Query: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304
+RVLD+NDN PAFDQ Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
Query: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364
R+LF + TG + V G LDYEE+ YQ+YVQA D GP + HCKVLV ++D NDNAPE
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
Query: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423
+ + + V E A P T+VA+ SV D+DS N +V L +PFRL + F N YT+V
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417
Query: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483
PLDRE Y +TV A D G P L++ ++++V++SD+NDN P F + Y +Y+ ENN+
Sbjct: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477
Query: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543
PG + V ATD DE NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537
Query: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601
+F VEA+D GSP L+ T N+ +VD ND+AP I+ P N + A E++PR+A G
Sbjct: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597
Query: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659
YL+T+V A+D+D G+NA L Y + + ++++LF+++ TGE+RT R++ + + L
Sbjct: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657
Query: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705
+ VRD+G+P LS++ + V +VD + P + QR +S T ++T
Sbjct: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715
Query: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751
L LIIAL +VSFIFLL +I+L+ ++C + YT + CC GG +
Sbjct: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774
Query: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806
+ A K + ++I + P + + +G + YCY+ CLT S
Sbjct: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834
Query: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNP 861
MF + T P GA +TG + Q I+ N ++ NE +
Sbjct: 835 MFLKPCSPSRSTDTEHNPCGA--------IVTGYTDQQPD---IISNGSILSNETKHQRA 883
Query: 862 DWRYSASLRAGMHSSVHLEEAGILRAGPG--GPDQQWPTVSSATPEPEAGEV-------S 912
+ Y ++SS +EA I+ + G +Q + AT ++ +
Sbjct: 884 ELSYLVDRPRRVNSSA-FQEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDLFSNCTE 942
Query: 913 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAI--ISIRQEPTNSQIDKSDF 970
G + W + P + +Q+ + +PG ++ + + P + F
Sbjct: 943 ECKALGHSDRCWMPSFVPSDGRQA--ADYRSNLHVPGMDSVPDTEVFETPEAQPGAERSF 1000
Query: 971 ITFGKKEETKKKKKKKK 987
TFGK++ ++K+
Sbjct: 1001 STFGKEKALHSTLERKE 1017
>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 658 bits (1698), Expect = 0.0
Identities = 390/970 (40%), Positives = 565/970 (58%), Gaps = 60/970 (6%)
Query: 26 LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
L LL LL L Q+RYSVPEE G+ VGN+++ LGL+ R+L +RI G
Sbjct: 13 LILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRT 72
Query: 86 SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
+ L+ SG+L RIDRE LC Q PRCL+++ L + + VE+EI+DINDN+
Sbjct: 73 --QLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130
Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
P+F + +++++E PGAR+ + A DPDVG NS+Q+Y+LSP+ HF LD++ +
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190
Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
ELVL + LDRE+ A HHLVLTA DGG P RS T +I V VLDTNDN+P F YRV+
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250
Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
+ E+ PPGT ++ + ASDPDEG NG++ Y ++++ LF ++ +TGE+ + LDY
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRKI-NEKQTPLFQLNENTGEISIAKSLDY 309
Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
EE S Y++ +QA D G + G K+L+ + DVNDN PEV++T L+SPV EN+ P T++A
Sbjct: 310 EECSFYEMEIQAEDVGA--LLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367
Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRLN-GFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
LSV+DQDSG N +V LPF+L GN Y LV LDRE V++YNITV A+D
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427
Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
G P L++ + + ++DINDNPP+F SYS YI ENNL G + ++ A DPD +ENA+V
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487
Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
TYS+ E +QG P++SY+SINS +G LYA+ SFDYE+ R+ + V A D G PPLSS ++
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547
Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
+++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
L + S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA+V +TVAV D
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667
Query: 684 VSKILPDTQRHVKS-PRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
+ ++L + S S +TLYL++A++ +S +FL + +L ++ R+
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRW-------- 719
Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
+ L + + + +P HF+ V + +TY + LTA S
Sbjct: 720 ---------HKSRLLQDSGGRL-VGVPAS-----HFVGVEEVQAFLQTYSQEVSLTADSR 764
Query: 803 SDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPD 862
+F P P+ A ++ S + + KNEA + PN D
Sbjct: 765 KSHLIF--------PQPNYADMLISQEGCEKNDSLLTSVDFHEYKNEA-DHGQQAPPNTD 815
Query: 863 WRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPV 915
WR+S + R G S + ++ G P+ Q+ T ++SA+ EA + S +
Sbjct: 816 WRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTL 866
Query: 916 GAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGK 975
G G + + +YGP Q P + IPGS A ++ + K+ G
Sbjct: 867 GGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGN 922
Query: 976 KEETKKKKKK 985
K+++ KK+KK
Sbjct: 923 KKKSGKKEKK 932
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 654 bits (1686), Expect = 0.0
Identities = 378/906 (41%), Positives = 540/906 (59%), Gaps = 80/906 (8%)
Query: 25 LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83
++ LLL LL + SQL Y+V EEQ G VGN+A LGL++ +L G + +
Sbjct: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
Query: 84 APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143
P YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV NP+ + VE+E+LDIND
Sbjct: 61 TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117
Query: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203
N P FP P+ +++SES PG RF +ESA DPDVG NS++ YE++P+ +F LD++ +
Sbjct: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177
Query: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244
++ ELVL K LDREQ A+H VLTAVDGG +P R+GTA ++
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
Query: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304
+RVLD+NDN PAFDQ Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
Query: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364
R+LF + TG + V G LDYEE+ YQ+YVQA D GP + HCKVLV ++D NDNAPE
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
Query: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423
+ + + V E A P T+VA+ SV D+DS N +V L +PFRL + F N YT+V
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417
Query: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483
PLDRE Y +TV A D G P L++ ++++V++SD+NDN P F + Y +Y+ ENN+
Sbjct: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477
Query: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543
PG + V ATD DE NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537
Query: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601
+F VEA+D GSP L+ T N+ +VD ND+AP I+ P N + A E++PR+A G
Sbjct: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597
Query: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659
YL+T+V A+D+D G+NA L Y + + ++++LF+++ TGE+RT R++ + + L
Sbjct: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657
Query: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705
+ VRD+G+P LS++ + V +VD + P + QR +S T ++T
Sbjct: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715
Query: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751
L LIIAL +VSFIFLL +I+L+ ++C + YT + CC GG +
Sbjct: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774
Query: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806
+ A K + ++I + P + + +G + YCY+ CLT S
Sbjct: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834
Query: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNP 861
MF + T P GA +TG + Q I+ N ++ NE R
Sbjct: 835 MFLKPCSPSRSTDTEHNPCGA--------IVTGYTDQQPD---IISNGSILSNEVRLKRK 883
Query: 862 DWRYSA 867
D S+
Sbjct: 884 DHHLSS 889
>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 651 bits (1679), Expect = 0.0
Identities = 396/973 (40%), Positives = 566/973 (58%), Gaps = 70/973 (7%)
Query: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
LLL LL L G AA+Q+RYS+PEE G+ VGN+ + LGLE + L +RI G
Sbjct: 15 LLLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRM-- 72
Query: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
+ L+ +G+L RIDRE LC Q PRCL+S +L + + + VEVEI+DINDN+PR
Sbjct: 73 QLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPR 132
Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
F + ++++ E+ AP +RF + DPDVG NS+Q ++LS + HF +D++ K
Sbjct: 133 FLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYP 192
Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
ELVL LDRE A++ LVLTA+DGG P RS AQI V VLD NDN+P F Q YRV +
Sbjct: 193 ELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVP 252
Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
E+ P GT V+ + A+D DEG +GE+ YS T ++ Q+F ++ TGE+ LDYE+
Sbjct: 253 ENLPVGTPVLAVTATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEISTSANLDYED 311
Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
+S Y++ V+A D GP + KVL+ I+DVNDN PEVV+T + E+A P T++A+
Sbjct: 312 SSFYELGVEARD-GP-GLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALF 369
Query: 388 SVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGI 446
V D+DSG N V+ + +LPF L GN Y LV + LDRE V +YNITVTATD G
Sbjct: 370 QVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGT 429
Query: 447 PQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTY 506
P L++ + + ++D NDNPP+F SYS+Y+ ENN G + +V A DPD +NA+V+Y
Sbjct: 430 PPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSY 489
Query: 507 SLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTAN 566
SL E +QG P++SYVSINS +G LYA+ SFDYE+ R+ + V A D G PPLSS V+ +
Sbjct: 490 SLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLS 549
Query: 567 VYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLA 625
++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y L
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 626 QTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVS 685
+ S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA+V +TVAV DR+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIP 669
Query: 686 KILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGG 744
IL D S + S++TLYL++A++ VS +FL +I+L ++ R+
Sbjct: 670 DILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRW---------- 719
Query: 745 FCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSD 804
QA+ A +P HF+ V G + +TY ++ LTA S
Sbjct: 720 --------HKSRLLQASGGGLASMPGS-----HFVGVEGVRAFLQTYSHEVSLTADSRKS 766
Query: 805 TFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQ-----P 859
+F P P+ A + +S + + L+I ++ ++ EPRQ P
Sbjct: 767 HLIF--------PQPNYADTLINQ------ESYEKSEPLLITQDLLETKGEPRQLQQAPP 812
Query: 860 NPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVS 912
N DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA + S
Sbjct: 813 NTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGS 863
Query: 913 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFIT 972
+G G + + +YGP Q P + IPGS A ++ + K+
Sbjct: 864 STLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGG 919
Query: 973 FGKKEETKKKKKK 985
G K+++ KK+KK
Sbjct: 920 NGNKKKSGKKEKK 932
>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
[Homo sapiens]
Length = 935
Score = 650 bits (1676), Expect = 0.0
Identities = 394/981 (40%), Positives = 573/981 (58%), Gaps = 78/981 (7%)
Query: 25 LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGA 84
LL LL + L L G A Q+RYSVPEE G+ VGN+++ LGLE R L +RI G
Sbjct: 13 LLLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRG- 71
Query: 85 PSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144
+ ++ SG+L RIDRE LCE C L++E+L + + + VEVEI+DINDN
Sbjct: 72 -KTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDN 130
Query: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204
+P F +++VSE PGARF + +A+DPDVG NS+Q+Y+LSP+ +F L L+ + +
Sbjct: 131 APSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGA 190
Query: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264
K ELVL LDRE+ A H L+LTA+DGG P R G I V VLD ND+ P F QS YRV
Sbjct: 191 KNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRV 250
Query: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
+ E+ GT V+ +NA+DPDEG NGE+ YS + S + ++F +D+ TGEV+V G LD
Sbjct: 251 SVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMES-KASEIFQLDSQTGEVQVRGSLD 309
Query: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384
+E+ Y++ +Q D G + +L+ +VDVNDNAPE+ +T + + EN+ P T++
Sbjct: 310 FEKYRFYEMEIQGQDGGGLFTT--TTMLITVVDVNDNAPEITITSSINSILENSPPGTVI 367
Query: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRLNG-FGNSYTLVVSGPLDRERVAVYNITVTATD 443
A+L+V DQDSG N +VS + LPF+L +GN Y L+ S LDRE V YNIT+TATD
Sbjct: 368 ALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATD 427
Query: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503
G P L++ + + ++D NDNPP F SYS YI ENN G + +V A DPD K+NA
Sbjct: 428 QGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNAL 487
Query: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563
VTYSL + +QG+P++SYVSINS +G LYA+ SFDYE+FR+ + V A+D G PPLSS V
Sbjct: 488 VTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNV 547
Query: 564 TANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622
+ +++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 SLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSY 607
Query: 623 HLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682
L + S+ LF V HTGE+RT R + D +L V V+D+G+P LSA+V +TVAV D
Sbjct: 608 RLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 667
Query: 683 RVSKILPD--TQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY--TAYG 738
+ ++L D + + + T S+++LYL++A++ VS IFL+ +I+L ++ +R+ +
Sbjct: 668 SIPEVLADLGSLESLANSET-SDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSRLL 726
Query: 739 TACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLT 798
A GG G+ HF+ V G + +TY ++ L
Sbjct: 727 QASEGGLAGMPTS-------------------------HFVGVDGVQAFLQTYSHEVSLI 761
Query: 799 AGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAV------- 851
A S +F P P+ ++ +S + + L+I ++ A+
Sbjct: 762 ADSQKSHLIF--------PQPNYGDTLISQ------ESCEKSEPLLIAEDSAIILGKCDP 807
Query: 852 SQNEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATP 904
+ N+ PN DWR+S + R G S + ++ G P+ Q+ T ++SA+
Sbjct: 808 TSNQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS- 860
Query: 905 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 964
EA + S +G G + + +YGP Q P + IPGS A ++ +
Sbjct: 861 --EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKR 914
Query: 965 IDKSDFITFGKKEETKKKKKK 985
K+ G K+++ KK+KK
Sbjct: 915 DGKAPAGGNGNKKKSGKKEKK 935
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 649 bits (1674), Expect = 0.0
Identities = 395/992 (39%), Positives = 579/992 (58%), Gaps = 79/992 (7%)
Query: 8 PAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGL 67
PA +H RL + + LLL +L A Q+ YSV EEQ G++VGN+A+ LGL
Sbjct: 5 PARPDHTRLLQ----------ICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGL 54
Query: 68 ELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHN 127
R L +RI G + L+ SG L RIDRE LC++ P C+ +LE+L +
Sbjct: 55 APRELAERGVRIVSRGRT--QLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLED 112
Query: 128 PVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYEL 187
V + VEVEI+D+NDN P F +++V+E+ PGARF + A DPDVG NS+Q Y+L
Sbjct: 113 TVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQL 172
Query: 188 SPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRV 247
+ + +F LD++ + K ELVL + LDRE+ A+HHLVLTA DGG P RSGTA+I + +
Sbjct: 173 NSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIIL 232
Query: 248 LDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQL 307
+DTNDN+P F Q Y V +RE+ P GT ++ + A+DPDEG+NG++ YS D+ QL
Sbjct: 233 VDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQL 291
Query: 308 FSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVL 367
F +++ +G++ ++GGLDYE++ Y I V+A D GP + KVLV ++D NDNAPEV +
Sbjct: 292 FQLNSLSGDITILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTV 349
Query: 368 TDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGP 426
T L S V E+++P T++A+ +V+D DSG N V+ + LPF L +GN Y L+
Sbjct: 350 TSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRT 409
Query: 427 LDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGV 486
LDRE V+ YNITVTATD G P L++ + +++ DINDNPP+F SYS YI ENN G
Sbjct: 410 LDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGA 469
Query: 487 LLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFF 546
+ ++ A DPD +NA +TYSL E QG P++SYVSINS +G LYA+ SFDYE+FR+
Sbjct: 470 SILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQ 529
Query: 547 VTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVT 605
+ + A D G PPLSS V+ +++V+D ND+ P ILYPT T+ S E+ PR+A +GYLVT
Sbjct: 530 LLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVT 589
Query: 606 KVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDN 665
KV+A+D DSGQNAWL Y L ++S+ LF V LHTGE+RT R + D L VVV+D+
Sbjct: 590 KVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDH 649
Query: 666 GEPSLSASVAITVAVVDRVSKILPDT-QRHVKSPRTYSEITLYLIIALSTVSFIFLLTII 724
G+P LSA+V +TVAV D + +L D + S +TLYL++A++ VS +FL +
Sbjct: 650 GQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVT 709
Query: 725 ILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGN 784
+L +K R+ + L + + A +P HF+ V G
Sbjct: 710 VLLALKLRRW-----------------HKSRLLHAEGSRL-AGVP-----ASHFVGVDGV 746
Query: 785 GSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLI 844
+ +TY ++ LTA S +F +Q + D+ ++ +S + + L+
Sbjct: 747 RAFLQTYSHEVSLTADSRKSHLIF-------------SQPSYADTL-ISRESCEKSEPLL 792
Query: 845 ILKNEAVSQNEPR----QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-- 898
I ++ ++ +P PN DWR+S + R G S + ++ G P+ Q+ T
Sbjct: 793 ITQDLLETKGDPNLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEM 846
Query: 899 -----VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAI 953
++SA+ EA + S +G G + + +YGP Q P + IPGS A
Sbjct: 847 LQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNAT 902
Query: 954 ISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 985
++ + K+ G K+++ KK+KK
Sbjct: 903 LT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 931
>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 641 bits (1653), Expect = 0.0
Identities = 386/974 (39%), Positives = 566/974 (58%), Gaps = 68/974 (6%)
Query: 26 LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
L LL LL +L ASQ+RYSVPEE G +VGN+++ L LE R L +RI G
Sbjct: 13 LVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRT 72
Query: 86 SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
+ L+ SG L RIDRE LC Q PRCL++ +VL + V + +E+E+ DIND++
Sbjct: 73 --QLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130
Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
P+F + +++++E PGAR+ + A DPDVG NS+Q+Y+LSP+ HF L+++ +
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190
Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
ELVL + LDRE+A HHLVLTA DGG P RS T +I V VLDTNDN+P F Q YRV+
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250
Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
+ E+ PPGT ++ ASD DEG NG++ Y ++++ LF ++ +TGE+ LDY
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWK-INEKQSLLFQLNENTGEISTAKSLDY 309
Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
EE S Y++ +QA D G + G KVL+ + DVNDN PEV +T L+SPV E+A T++
Sbjct: 310 EECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367
Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
+ + +D+DSG N +V ++ L F L N + Y L+ + LDRE+ + YNITVTATD
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427
Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
G P L++ + ++++DINDNPP+F + SYS+Y+ ENN G + +V A DPD EN+ V
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487
Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
YSL E IQG P+++YVSINS +G LYA+ SFDYE+FR+ + V A D GSPPLSS V+
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547
Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
L + S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA+V +TVA+ D
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667
Query: 684 VSKILPDT-QRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
+ IL D + + S++TLYL++A++ VS +FL +I L ++
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALR------------ 715
Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
+R + L + ++ + A +P HF+ V G + +TY + LTA S
Sbjct: 716 -----LRHWHSSHLLRATSDGL-AGVP-----TSHFVGVDGVRAFLQTYSQEFSLTADSR 764
Query: 803 SDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEP----RQ 858
+F P P+ A ++ +N + + ++ ++ P
Sbjct: 765 KSHLIF--------PQPNYADTLISQQ-----SCEKNEPLCVSVDSKFPIEDTPLVPQAP 811
Query: 859 PNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEV 911
PN DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA +
Sbjct: 812 PNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADG 862
Query: 912 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 971
S +G G + + +YGP Q P + IPGS A ++ + K+
Sbjct: 863 SSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAG 918
Query: 972 TFGKKEETKKKKKK 985
G K+++ KK+KK
Sbjct: 919 GNGNKKKSGKKEKK 932
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 640 bits (1651), Expect = 0.0
Identities = 368/800 (46%), Positives = 504/800 (63%), Gaps = 40/800 (5%)
Query: 15 RLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP 74
RL R L+LL +LL L +Q+RYSVPEE G+ VG+++R LGLE R L
Sbjct: 5 RLHRDYKGLVLLGILLGTLW---ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAE 61
Query: 75 GCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAV 134
+RI G + L+ SG+L RIDRE LC +C L+L++L + V + V
Sbjct: 62 RGVRIIPRGRT--QLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGV 119
Query: 135 EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFE 194
EVE+ DINDN+P F ++++SE+ A RF + A DPD+G NS+Q+YELSP+ HF
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFS 179
Query: 195 LDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNS 254
L ++ + SK ELVL++ LDRE+ A HHLVLTA DGG P R+GTA+I V VLD NDN+
Sbjct: 180 LIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNA 239
Query: 255 PAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDAST 314
PAF Q YR + E+ GT ++ +NA+DPDEG N E+RYS Y D+ Q+F +D ++
Sbjct: 240 PAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNS 298
Query: 315 GEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPV 374
G + IG LD+EE+ YQ+ VQA D + KVL+ ++DVNDNAPEVVLT L S V
Sbjct: 299 GTISTIGELDHEESGFYQMEVQAMDN--AGYSARAKVLITVLDVNDNAPEVVLTSLASSV 356
Query: 375 PENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVA 433
PEN+ T++A+L+VNDQDS N +V ++ LPF+L +GN Y+LV LDRE+V
Sbjct: 357 PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVP 416
Query: 434 VYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQA 493
YNITVTATD G P L++ + + ++D NDNPP F + SYS YI ENN GV L +V A
Sbjct: 417 SYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTA 476
Query: 494 TDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQD 553
DPD +ENA++TYSL E IQG ++SYVSINS +G LYA++SFDYE+FR+ V V A+D
Sbjct: 477 HDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARD 536
Query: 554 KGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDS 612
G PPLSS V+ +++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D
Sbjct: 537 NGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDR 596
Query: 613 DSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSA 672
DSGQNAWL Y L + S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA
Sbjct: 597 DSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 656
Query: 673 SVAITVAVVDRVSKILPDTQRHVKSPRT--YSEITLYLIIALSTVSFIFLLTIIILSIIK 730
+V +TVAV D + ++L D ++SP S++TLYL++A++ VS +FL +I+L ++
Sbjct: 657 TVTLTVAVADSIPQVLADL-GSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALR 715
Query: 731 CYRY--TAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLT 788
R+ + A GG G +PA HF+ V G +
Sbjct: 716 LRRWHKSRLLQASGGGLTG----APAS---------------------HFVGVDGVQAFL 750
Query: 789 KTYCYKACLTAGSGSDTFMF 808
+TY ++ LT S +F
Sbjct: 751 QTYSHEVSLTTDSRKSHLIF 770
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 640 bits (1650), Expect = 0.0
Identities = 391/977 (40%), Positives = 560/977 (57%), Gaps = 77/977 (7%)
Query: 28 LLLLLLLLLPGPA-ASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPS 86
+LL L +P A A Q+ YS+PEE G+ VGN+++ LGL R L +RI G
Sbjct: 18 VLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRG--R 75
Query: 87 PRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSP 146
+ L+ SG+L RIDRE LC Q RC++S +L + V + +E+E+ DINDN+P
Sbjct: 76 TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135
Query: 147 RFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKV 206
+F N ++++E+VA G RF + A DPDVG NS+Q+Y+LSP++HF L ++ K
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195
Query: 207 LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266
ELVL LDRE+ A+HHLVLTA DGG P RSGT +SV V D NDN+P F YRV +
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSV 255
Query: 267 REDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE 326
E+ P GT ++ + A+D DEG+NGE+ YS D + F ++ TGE+++ LDYE
Sbjct: 256 PENLPVGTQLLTVTATDRDEGANGEVTYSFRK-LPDTQLLKFQLNKYTGEIKISENLDYE 314
Query: 327 EASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAV 386
E Y+I +QA D G KVL+ + DVNDN+PE+ +T L+SPV E++ T+VA+
Sbjct: 315 ETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372
Query: 387 LSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGG 445
L+V+D DS N +V+ + A LPF+L + Y LV+ LDRE+V+ YNITVTATDGG
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGG 432
Query: 446 IPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVT 505
P L++ ++++DINDNPP+F + SY YI ENN G + +V A DPD KENA++
Sbjct: 433 SPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQII 492
Query: 506 YSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTA 565
YSL E IQG+P++SY+SINS +G LYA+ SFDYE+F E + V A D G PPLSS V+
Sbjct: 493 YSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSL 552
Query: 566 NVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL 624
+++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y L
Sbjct: 553 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 612
Query: 625 AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRV 684
+ S+ LF V HTGE+RT R + D +L V V+D+G+P LSA+V +TVAV D +
Sbjct: 613 LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 672
Query: 685 SKILPDTQRHVKSPRT--YSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY--TAYGTA 740
++L D +SP S++TLYL++A++ VS +FL +I+L + R+ + A
Sbjct: 673 PQVLADL-GSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQA 731
Query: 741 CCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAG 800
GG GV HF+ V G + +TY ++ LTA
Sbjct: 732 SGGGLTGVS-------------------------GSHFVGVDGVRAFLQTYSHEVSLTAD 766
Query: 801 SGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKN-----EAVSQNE 855
S +F P P+ A ++ +S + L +L + E
Sbjct: 767 SRKSHLIF--------PQPNYADTLISQ------ESCEKNDPLSLLDDSKFPIEDTPLVP 812
Query: 856 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEA 908
PN DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA
Sbjct: 813 QAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EA 863
Query: 909 GEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKS 968
+ S +G G + + +YGP Q P + IPGS A ++ + K+
Sbjct: 864 ADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKA 919
Query: 969 DFITFGKKEETKKKKKK 985
G K+++ KK+KK
Sbjct: 920 PAGGNGNKKKSGKKEKK 936
Score = 143 bits (360), Expect = 9e-34
Identities = 143/532 (26%), Positives = 233/532 (43%), Gaps = 97/532 (18%)
Query: 209 LVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRE 268
+ ++ +E LVL + GIP +G QIS + + +L +
Sbjct: 1 MAAQRNRSKESKDCSGLVLLCLFFGIPWEAGARQISYSIPE---------------ELEK 45
Query: 269 DSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE- 327
S G + L + + G S QLFS++ +G + G +D EE
Sbjct: 46 GSFVGNISKDLGLAPRELAERG------VRIVSRGRTQLFSLNPRSGSLITAGRIDREEL 99
Query: 328 -------ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAP------------EVVLT 368
S+ I V+ DR V + G + +++ D+NDNAP E V
Sbjct: 100 CAQSARCVVSFNILVE--DR--VKLFG---IEIEVTDINDNAPKFQAENLDVKINENVAA 152
Query: 369 DLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLD 428
+ P+PE P+ V V S+ PN+ SL +++ R NG LV+ LD
Sbjct: 153 GMRFPLPEAIDPD--VGVNSLQSYQLSPNKHFSLRVQS----RANGV-KYPELVLEHSLD 205
Query: 429 RERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLL 488
RE A++++ +TA+DGG P + + V + D NDN P F Y + + EN G L
Sbjct: 206 REEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQL 265
Query: 489 CTVQATDPDEKENAEVTYSLLEREIQGLPVTSYV--SINSASGSLYAVNSFDYEKFREFF 546
TV ATD DE N EVTYS + LP T + +N +G + + DYE+ +
Sbjct: 266 LTVTATDRDEGANGEVTYS-----FRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYE 320
Query: 547 VTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTK 606
+ ++A+D G+ +T + V D+ND++P + ++ F V +P G +V
Sbjct: 321 IEIQAEDGGA--YLATAKVLITVEDVNDNSPEL------TITSLFSPVTEDSPLGTVVAL 372
Query: 607 VIAMDSDSGQN--------AWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNL 658
+ D DS QN A+L + L ++ D +++ +H R + E S++N+
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSID-SYYRLVIH-------RALDREQVSSYNI 424
Query: 659 TVVVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLII 710
TV D G P LS + V D + D +P T+S+++ + I
Sbjct: 425 TVTATDGGSPPLSTEAHFMLQVAD-----IND------NPPTFSQVSYFTYI 465
>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 637 bits (1644), Expect = 0.0
Identities = 390/970 (40%), Positives = 557/970 (57%), Gaps = 61/970 (6%)
Query: 26 LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
L LL L L LL A + YSVPEE G+ VGN+A+ LGL+ + L G +RI G
Sbjct: 13 LMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRM 72
Query: 86 SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
L+ SG+L RIDRE LC Q CL+S +L + + + VEVEI+DINDN+
Sbjct: 73 P--LFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNT 130
Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
P+F + +++E PG R + QD DVG NS+Q+Y+LS + HF LD++ + +
Sbjct: 131 PQFQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQ 190
Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
E+VL+ LDRE+ A+HHL+LTA DGG P RSGT +I ++V+D NDN PAF Q+ Y +
Sbjct: 191 HPEMVLQSPLDREEEAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHIN 250
Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
+ E+ P GT ++ +NA+DPDEG+NGE+ YS + R Q+F +D+ TGE+ LD+
Sbjct: 251 VPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIFRLDSYTGEISNKEPLDF 309
Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
EE Y + VQA D + KVL+ ++DVNDNAPEV +T + + VPEN P TI+A
Sbjct: 310 EEYKMYSMEVQAQD--GAGLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIA 367
Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRLNGF-GNSYTLVVSGPLDRERVAVYNITVTATDG 444
++SV+DQDSG N + + LPF+L N Y LV LDRE ++ YNIT+TA D
Sbjct: 368 LISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQ 427
Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
G P L++ + + ++DINDN P F +DSYS YI ENN G + +V+A D D ENA++
Sbjct: 428 GTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQI 487
Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
TYSL+E IQG P+++Y+SINS +G LYA+ SFDYE+FR+ + V A+D G PPLSS V+
Sbjct: 488 TYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVS 547
Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
+++++D ND+AP ILYP T+ S E+ P +A GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 LSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
L + S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA+V +TVAV DR
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADR 667
Query: 684 VSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
+S IL D S + S++TLYL++A + VS +FL +I+L + R+
Sbjct: 668 ISDILADLGSLEPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRW-------- 719
Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
QA+ A +P HF+ V G + +TY ++ LTA S
Sbjct: 720 ----------HKSRLLQASGGGLASMPGS-----HFVGVDGVRAFLQTYSHEVSLTADSR 764
Query: 803 SDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPD 862
+F P P+ A ++ +L+ K E SQ P PN D
Sbjct: 765 KSHLIF--------PQPNYADTLISQESCEKKGFLSAPQSLLEDKKEPFSQQAP--PNTD 814
Query: 863 WRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPV 915
WR+S + R G S + ++ G P+ Q+ T ++SA+ EA + S +
Sbjct: 815 WRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTL 865
Query: 916 GAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGK 975
G G + + +YGP Q P + IPGS A ++ + K+ G
Sbjct: 866 GGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGN 921
Query: 976 KEETKKKKKK 985
K+++ KK+KK
Sbjct: 922 KKKSGKKEKK 931
>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 635 bits (1639), Expect = 0.0
Identities = 384/971 (39%), Positives = 555/971 (57%), Gaps = 62/971 (6%)
Query: 26 LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
L LL LL L + Q+RYSV EE G+ VGN+A LGLE R L +RI G
Sbjct: 13 LALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRT 72
Query: 86 SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
+ L+ SG+L ERIDRE LC Q P CL+ + +L + + + VE+EI DINDN+
Sbjct: 73 --QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNA 130
Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
P FP ++++ E PG RF I++A DPDVG NS+Q Y+LSP+++F L + + E +K
Sbjct: 131 PNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAK 190
Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
ELVL + LDRE+ +H LVL A DGG P SG I V VLD NDN P F Q YRV
Sbjct: 191 YPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVS 250
Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
+ E+ P GT ++ +NA+DPDEG N ++ Y L + ++F +++ +GEV ++ LDY
Sbjct: 251 VWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPG-KIAEIFHLNSVSGEVSILKSLDY 309
Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
E+A Y+I ++A D GP + K+LV ++DVNDNAPE+ +T L S VPE T +A
Sbjct: 310 EDAMFYEIKIEAQD-GP-GLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIA 367
Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
++ V+D+DSG N +V + + LPF+L Y LV + LDRE+++ YNI++ A+DG
Sbjct: 368 LIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDG 427
Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
G P L++ + + + DINDNPP+F SYS YI ENN G + +V A DPD NA +
Sbjct: 428 GSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARI 487
Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
TY+L E +QG P++S+VSINS +G LYA+ SFDYE+FR+ + V A D G+PPLSS V+
Sbjct: 488 TYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVS 547
Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
N++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 LNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
L + S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA+V +TVAV DR
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADR 667
Query: 684 VSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
+ IL D S + S++TLYL++A++ VS +FL +I+L ++ R+
Sbjct: 668 IPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLLQA 727
Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
G G +P HF+ G + +TY ++ LTA S
Sbjct: 728 SG--GGLASTPGS---------------------HFVGADGVRAFLQTYSHEVSLTADSR 764
Query: 803 SDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEA-VSQNEPRQPNP 861
+F P P+ A ++ + +L+ +K ++ + Q P PN
Sbjct: 765 KSHLIF--------PQPNYADTLISQESCEKSEPLLITQDLLEMKGDSNLLQQAP--PNT 814
Query: 862 DWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPP 914
DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA + S
Sbjct: 815 DWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSST 865
Query: 915 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 974
+G G + + +YGP Q P + IPGS A ++ + K+ G
Sbjct: 866 LGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNG 921
Query: 975 KKEETKKKKKK 985
K+++ KK+KK
Sbjct: 922 NKKKSGKKEKK 932
>gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 629 bits (1622), Expect = e-180
Identities = 333/712 (46%), Positives = 468/712 (65%), Gaps = 8/712 (1%)
Query: 26 LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
L LL LL L Q+RYSVPEE G+ VGN+++ LGL+ R+L +RI G
Sbjct: 13 LILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRT 72
Query: 86 SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
+ L+ SG+L RIDRE LC Q PRCL+++ L + + VE+EI+DINDN+
Sbjct: 73 --QLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130
Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
P+F + +++++E PGAR+ + A DPDVG NS+Q+Y+LSP+ HF LD++ +
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190
Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
ELVL + LDRE+ A HHLVLTA DGG P RS T +I V VLDTNDN+P F YRV+
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250
Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
+ E+ PPGT ++ + ASDPDEG NG++ Y ++++ LF ++ +TGE+ + LDY
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRK-INEKQTPLFQLNENTGEISIAKSLDY 309
Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
EE S Y++ +QA D G + G K+L+ + DVNDN PEV++T L+SPV EN+ P T++A
Sbjct: 310 EECSFYEMEIQAEDVG--ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367
Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
LSV+DQDSG N +V LPF+L GN Y LV LDRE V++YNITV A+D
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427
Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
G P L++ + + ++DINDNPP+F SYS YI ENNL G + ++ A DPD +ENA+V
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487
Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
TYS+ E +QG P++SY+SINS +G LYA+ SFDYE+ R+ + V A D G PPLSS ++
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547
Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
+++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
L + S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA+V +TVAV D
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667
Query: 684 VSKILPDTQRHVKS-PRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734
+ ++L + S S +TLYL++A++ +S +FL + +L ++ R+
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRW 719
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 628 bits (1619), Expect = e-180
Identities = 384/973 (39%), Positives = 556/973 (57%), Gaps = 65/973 (6%)
Query: 24 LLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLG 83
LLLP +LL L PG + Q+RYS+PEE G+ VGN+A+ LGLE + L +RI G
Sbjct: 13 LLLPFMLLGTLCEPG--SGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRG 70
Query: 84 APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143
+ L+ SG+L RIDRE LC Q P C+++ +L N + + VEVEI+DIND
Sbjct: 71 RT--QLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIND 128
Query: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203
N PRF +++V+E+ A G R + A+D DVG NS+++Y+LS + HF LD+ +
Sbjct: 129 NFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDG 188
Query: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYR 263
K ELVL + LDRE+ +H L+LTA+DGG P SGT I V VLD NDN+P F S Y
Sbjct: 189 QKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYS 248
Query: 264 VQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGL 323
V + E+ P GT ++ L A+DPDEG NG+L YS + ++ + F +D++ GE+ + L
Sbjct: 249 VSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRN-EEEKISETFQLDSNLGEISTLQSL 307
Query: 324 DYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTI 383
DYEE+ Y + V A D G + KV+V + DVNDNAPEV+LT L S + E+ P T+
Sbjct: 308 DYEESRFYLMEVVAQDGGA--LVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGTV 365
Query: 384 VAVLSVNDQDSGPNRKVSLGLEATLPFRLN-GFGNSYTLVVSGPLDRERVAVYNITVTAT 442
+A+ SV+D DSG N +++ + LPF+L N Y L+ + LDRE + YNIT+T
Sbjct: 366 IALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVM 425
Query: 443 DGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENA 502
D G P L++ + ++++D+NDNPP+F + SYS + ENN GV + +V A DPD +NA
Sbjct: 426 DHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNA 485
Query: 503 EVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSST 562
VTYSL E QG P++SYVSINS +G LYA+ SFDYE+ R+ + V A D G+PPLSS
Sbjct: 486 RVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSN 545
Query: 563 VTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLF 621
V+ +++V+D ND+ P ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL
Sbjct: 546 VSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLS 605
Query: 622 YHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVV 681
Y L + S+ LF V LHTGE+RT R + D +L V V D+G+P LSA+ +TVAV
Sbjct: 606 YRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAVA 665
Query: 682 DRVSKILPDTQRHVKSPRTYSEI--TLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGT 739
DR+ IL D +K+P ++ TLYL++A++ VS +FL +I+L +++ R+
Sbjct: 666 DRIPDILADLGS-IKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHK--- 721
Query: 740 ACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTA 799
QA + A +P HF+ V G + +TY ++ LTA
Sbjct: 722 ---------------SRLLQAEGSRLAGVPAS-----HFVGVDGVRAFLQTYSHEVSLTA 761
Query: 800 GSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQP 859
S +F P P+ A +++ + + + K E Q P P
Sbjct: 762 DSRKSHLIF--------PQPNYADTLLSEESCEKSEPLLMSDKVDANKEERRVQQAP--P 811
Query: 860 NPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVS 912
N DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA + S
Sbjct: 812 NTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGS 862
Query: 913 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFIT 972
+G G + + +YGP Q P + IPGS A ++ + K+
Sbjct: 863 STLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGG 918
Query: 973 FGKKEETKKKKKK 985
G K+++ KK+KK
Sbjct: 919 NGNKKKSGKKEKK 931
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 627 bits (1617), Expect = e-179
Identities = 372/965 (38%), Positives = 552/965 (57%), Gaps = 52/965 (5%)
Query: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
LL L G Q+RY VPEE G VGNVA+ L+ L L++ G + R+
Sbjct: 17 LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQV--AGEVNQRH 74
Query: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
+DL SGAL + IDREALC C++ LE + P+ + EVEI+D+ND++PRFP
Sbjct: 75 FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134
Query: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
R L++ E+ PG RF +E AQD DVG+NS+ +Y LS +EHF LD+K + S V EL
Sbjct: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194
Query: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
+L K LDRE+ + + LVLTAVDGG P RSGTA++ V VLD NDN+PAF QS+YR+ + E
Sbjct: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254
Query: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
+P G ++++LNASDPD G +G + + S +T DR R LFS+ +TG++ ++G LD+E +
Sbjct: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314
Query: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
Y+ V+A D G M HC + VD++DVNDNAP + +T +PE+A P T+VA++SV
Sbjct: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374
Query: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
D DSG N VSL + LPF L + F N ++LV +GPLDRE + Y+I VTA+D G P
Sbjct: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434
Query: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
L++ RT+ + ISD+NDNPPSF + S+ +++ ENN PG LLC++ A+DPD NA ++YSL
Sbjct: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494
Query: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
LE + + +S++S+N +G+++A SFDYE+ + V+A+D+G+PPLSSTVT ++
Sbjct: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554
Query: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
V+D+ND+AP +L P + S + +P + AG+L+TKV A+D DSG NAW+ Y L +
Sbjct: 555 VLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAP 614
Query: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
D LF V + GE+RT + + L +VV+D+G P LS SV + V++ + ++
Sbjct: 615 DPSLFAVSRYAGEVRTAVPIPADLPPQ-KLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVV 673
Query: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC-GGFCG 747
PD + S +TLYL ++L + F+ + + L + KC R A G C G C
Sbjct: 674 PDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVAL-LSKCLRGAACGVTCFPAGTCA 732
Query: 748 VRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807
RS +N I RI G F++V G+ ++ +A + SD+FM
Sbjct: 733 CLTRSRRREGLPPSNGI-LRIQLGSDDPIKFVDVGGH-----SHGCTPLASAPTRSDSFM 786
Query: 808 FYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPDWRYSA 867
+ + G + + S L G E PN DWR+S
Sbjct: 787 MVKSPSAPMAG-EPVRPSCPPSDLLYGL-------------------EQAPPNTDWRFSQ 826
Query: 868 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVN 920
+ R G S + ++ G P+ Q+ T ++SA+ EA + S +G G
Sbjct: 827 AQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAG 877
Query: 921 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 980
+ + +YGP Q P + IPGS A ++ + K+ G K+++
Sbjct: 878 TMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSG 933
Query: 981 KKKKK 985
KK+KK
Sbjct: 934 KKEKK 938
>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
[Homo sapiens]
Length = 934
Score = 626 bits (1614), Expect = e-179
Identities = 368/965 (38%), Positives = 551/965 (57%), Gaps = 58/965 (6%)
Query: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
+LLLL A++ + Y +PEE+ G VGNV LGL+L L R+ + S R+
Sbjct: 19 VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76
Query: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
E++ +G +FVN+R+DRE LC P C ++LE++ NP+ + +VEV I DINDN+P FP
Sbjct: 77 FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136
Query: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
+L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++ ++++K EL
Sbjct: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196
Query: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
VL + LDRE+ LVLTA+DGG PA S + I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256
Query: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
+P GT VV++ A+D DEG NGE+ YS S+ RQLF++D TG + + G LD+E+
Sbjct: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316
Query: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
++IY+QA D+G P HCKVLV++VDVNDNAPE+ +T +YSPVPE+A T++A+LSV
Sbjct: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376
Query: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
D D+G N V+ + LPF L + N +TL S LDRE V YN+++TA D G P
Sbjct: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436
Query: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
L++L ++V++SDINDNPP + SY +YI+ENNLPG + + DPD +NA +++ L
Sbjct: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496
Query: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
LE+ + V Y +IN +G + ++ DYE REF +T D G+P L++ ++ N++
Sbjct: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556
Query: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
V D ND+AP +LYP SS EM+PR AG+LV++V+ D+D+G NAWL Y L +
Sbjct: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
Query: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
+ LF + LHTG+I T R + D LTV+++DNGEPSLS + +TV+V + +
Sbjct: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
Query: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFCGV 748
+ +T YL+++L VS F++T+ + I K Y++
Sbjct: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDL-------- 726
Query: 749 RERSP-AELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807
R+P + LY+ ++ A G + PH ++ LT S +
Sbjct: 727 -YRAPVSSLYRTPGPSLHADAVRGGLMSPHLY-------------HQVYLTTDSRRSDPL 772
Query: 808 FYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPDWRYSA 867
GA A+ SR T +S +L E+ + PN DWR+S
Sbjct: 773 LKKPGA----------ASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQ 822
Query: 868 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVN 920
+ R G S + ++ G P+ Q+ T ++SA+ EA + S +G G
Sbjct: 823 AQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAG 873
Query: 921 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 980
+ + +YGP Q P + IPGS A ++ + K+ G K+++
Sbjct: 874 TMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSG 929
Query: 981 KKKKK 985
KK+KK
Sbjct: 930 KKEKK 934
>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 623 bits (1606), Expect = e-178
Identities = 380/972 (39%), Positives = 557/972 (57%), Gaps = 69/972 (7%)
Query: 29 LLLLLLLLPGPA-ASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
LL +LL P A A ++ YSV EE G+ VG++A+ LGLE R L +RI G
Sbjct: 15 LLSILLGTPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRT-- 72
Query: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
+ L+ SG+L RIDRE +C Q RCL++ +L + + + ++VEI+DINDN PR
Sbjct: 73 QLFALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPR 132
Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
F +++ E+ APG RF + A DPDVG NS+Q+Y+LSP+ HF L ++ + +K
Sbjct: 133 FLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYP 192
Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
ELVL + LDRE+ +HHLVLTA DGG P RS TA I V V+D ND++P F Y+V +
Sbjct: 193 ELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVP 252
Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
E+ P GT ++ ++A D DEG NGE+ YS T + +F +++ TGE+ + GLDYEE
Sbjct: 253 ENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSLTGEISTLEGLDYEE 311
Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
+ Y++ VQA D GP + KVL+ ++DVNDNAPEV +T L S +PE+ T++A+
Sbjct: 312 TAFYEMEVQAQD-GPGSLT-KAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALF 369
Query: 388 SVNDQDSGPNRKVSLGLEATLPFRLN-GFGNSYTLVVSGPLDRERVAVYNITVTATDGGI 446
+ D+DSG N +V+ + LPF+L N Y LV + LDRE +++YNIT+ ATDGG
Sbjct: 370 YLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGT 429
Query: 447 PQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTY 506
P L+ + ++++D NDNPP+F SYS+YI ENN G + V A D D ++NA++TY
Sbjct: 430 PPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITY 489
Query: 507 SLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTAN 566
SL E IQG PV+SYVSINS +G LYA+ SFDYE+ RE + V A D G PPLSS ++ +
Sbjct: 490 SLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLS 549
Query: 567 VYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLA 625
++V+D ND+ P ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y L
Sbjct: 550 LFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLL 609
Query: 626 QTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVS 685
+ S+ LF V L+TGE+RT R + D +L V V+D+G+P LSA+V +TVAV D +
Sbjct: 610 KASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIP 669
Query: 686 KILPDTQRHVKSPRTYS-EITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGG 744
++L D S Y+ ++TLYL++A++TVS +FL +++L ++ R+
Sbjct: 670 EVLADLGSLEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRWHK-------- 721
Query: 745 FCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSD 804
QA+ A +P HF+ + G + +TY ++ LTA S
Sbjct: 722 ----------SRLLQASEGGLANVPTS-----HFVGMDGVQAFLQTYSHEVSLTADSRKS 766
Query: 805 TFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPR----QPN 860
+F P P+ ++ +N L + + +N P PN
Sbjct: 767 HLIF--------PQPNYVDMLISQE-----SCEKNDSLLTSVDFQECKENLPSIQQAPPN 813
Query: 861 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSP 913
DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA + S
Sbjct: 814 TDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSS 864
Query: 914 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 973
+G G + + +YGP Q P + IPGS A ++ + K+
Sbjct: 865 TLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGN 920
Query: 974 GKKEETKKKKKK 985
G K+++ KK+KK
Sbjct: 921 GNKKKSGKKEKK 932
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 622 bits (1604), Expect = e-178
Identities = 352/804 (43%), Positives = 498/804 (61%), Gaps = 41/804 (5%)
Query: 8 PAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGL 67
PA +H RL + + LLL +L A Q+ YSV EEQ G++VGN+A+ LGL
Sbjct: 5 PARPDHTRLLQ----------ICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGL 54
Query: 68 ELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHN 127
R L +RI G + L+ SG L RIDRE LC++ P C+ +LE+L +
Sbjct: 55 APRELAERGVRIVSRGRT--QLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLED 112
Query: 128 PVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYEL 187
V + VEVEI+D+NDN P F +++V+E+ PGARF + A DPDVG NS+Q Y+L
Sbjct: 113 TVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQL 172
Query: 188 SPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRV 247
+ + +F LD++ + K ELVL + LDRE+ A+HHLVLTA DGG P RSGTA+I + +
Sbjct: 173 NSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIIL 232
Query: 248 LDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQL 307
+DTNDN+P F Q Y V +RE+ P GT ++ + A+DPDEG+NG++ YS D+ QL
Sbjct: 233 VDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQL 291
Query: 308 FSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVL 367
F +++ +G++ ++GGLDYE++ Y I V+A D GP + KVLV ++D NDNAPEV +
Sbjct: 292 FQLNSLSGDITILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTV 349
Query: 368 TDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGP 426
T L S V E+++P T++A+ +V+D DSG N V+ + LPF L +GN Y L+
Sbjct: 350 TSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRT 409
Query: 427 LDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGV 486
LDRE V+ YNITVTATD G P L++ + +++ DINDNPP+F SYS YI ENN G
Sbjct: 410 LDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGA 469
Query: 487 LLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFF 546
+ ++ A DPD +NA +TYSL E QG P++SYVSINS +G LYA+ SFDYE+FR+
Sbjct: 470 SILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQ 529
Query: 547 VTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVT 605
+ + A D G PPLSS V+ +++V+D ND+ P ILYPT T+ S E+ PR+A +GYLVT
Sbjct: 530 LLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVT 589
Query: 606 KVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDN 665
KV+A+D DSGQNAWL Y L ++S+ LF V LHTGE+RT R + D L VVV+D+
Sbjct: 590 KVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDH 649
Query: 666 GEPSLSASVAITVAVVDRVSKILPDT-QRHVKSPRTYSEITLYLIIALSTVSFIFLLTII 724
G+P LSA+V +TVAV D + +L D + S +TLYL++A++ VS +FL +
Sbjct: 650 GQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVT 709
Query: 725 ILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGN 784
+L +K R+ + L + + A +P HF+ V G
Sbjct: 710 VLLALKLRRW-----------------HKSRLLHAEGSRL-AGVP-----ASHFVGVDGV 746
Query: 785 GSLTKTYCYKACLTAGSGSDTFMF 808
+ +TY ++ LTA S +F
Sbjct: 747 RAFLQTYSHEVSLTADSRKSHLIF 770
>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 622 bits (1604), Expect = e-178
Identities = 378/976 (38%), Positives = 564/976 (57%), Gaps = 60/976 (6%)
Query: 20 MPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRI 79
+P L LL LL L A Q+RYSV EE G+ VGN+A+ LGLE L +RI
Sbjct: 7 LPHCRKLVLLCFLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRI 66
Query: 80 NHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEIL 139
G + L+ SG+L RIDRE LC Q CLL+ +L + + + +VEVEI
Sbjct: 67 VSRGRS--QLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEIT 124
Query: 140 DINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKP 199
DINDN+PRF +L++SE+ PG R +++A D DVG N++Q Y L+P++HF LD++
Sbjct: 125 DINDNAPRFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRR 184
Query: 200 LQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQ 259
+ +K ELVL + LDRE+ A+HHLVL A DGG P SGT++I V+VLD NDN+P F Q
Sbjct: 185 GADGNKYPELVLERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQ 244
Query: 260 STYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRV 319
YR+ + E++ GT ++ + A+D DEG ++ Y L + ++F + +++GE+ +
Sbjct: 245 PEYRISIPENTLVGTRILTVTATDADEGYYAQVVYFLEKSPGETS-EVFELKSTSGELTI 303
Query: 320 IGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENAT 379
I LDYE+A+ ++I ++A D GP + KV+V ++DVNDNAPE +T S V E++
Sbjct: 304 IKDLDYEDATFHEIDIEAQD-GP-GLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSL 361
Query: 380 PNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLN-GFGNSYTLVVSGPLDRERVAVYNIT 438
P TI+ + +V+D+DSG N + L LPF+L N Y LV + LDRE+ + YNIT
Sbjct: 362 PGTIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNIT 421
Query: 439 VTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDE 498
+TA DGG P L++ + ++++DINDN P+F SYS YI ENN G + +V A DPD
Sbjct: 422 LTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDS 481
Query: 499 KENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPP 558
+NA VTYS E +QG P++SY+SINS +G LYA+ SFDYE+ R+ V V A+D G+PP
Sbjct: 482 NDNAHVTYSFAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPP 541
Query: 559 LSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQN 617
LSS V+ +++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQN
Sbjct: 542 LSSNVSLSLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQN 601
Query: 618 AWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAIT 677
AWL YHL + S+ LF V LHTGE+RT R + D +L V ++D+G+P LSA+V +T
Sbjct: 602 AWLSYHLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLT 661
Query: 678 VAVVDRVSKILPDTQRHVKSP-RTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTA 736
VAV DR+ IL D S S++TLYL++A++ VS +FL +I+L + R+
Sbjct: 662 VAVADRIPDILADLGSLEPSAIPNDSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRW-- 719
Query: 737 YGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKAC 796
+ L + + ++ G++ HF+ V G + +TY ++
Sbjct: 720 ---------------HKSRLLQASGGSLT-----GMQ-SSHFVGVDGVRAFLQTYSHEVS 758
Query: 797 LTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEP 856
LTA S +F P P+ A ++ + + +A ++ + + ++
Sbjct: 759 LTADSRKSHLIF--------PQPNYADTLISQE-SCEKKDFLSAPQSLLEEEREETFSQQ 809
Query: 857 RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAG 909
PN DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA
Sbjct: 810 APPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAA 860
Query: 910 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 969
+ S +G G + + +YGP Q P + IPGS A ++ + K+
Sbjct: 861 DGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAP 916
Query: 970 FITFGKKEETKKKKKK 985
G K+++ KK+KK
Sbjct: 917 AGGNGNKKKSGKKEKK 932
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 621 bits (1602), Expect = e-178
Identities = 383/1001 (38%), Positives = 548/1001 (54%), Gaps = 98/1001 (9%)
Query: 28 LLLLLLLLLPGPAAS-QLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPS 86
LLLL LLL A S QL YS+PEE G VG +A+ LGLEL L P R+ G
Sbjct: 13 LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGD 72
Query: 87 PRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSP 146
LE++L +G LFVN RIDRE LC +R C + LEV+ P+ V VEV + DINDN P
Sbjct: 73 --LLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPP 130
Query: 147 RFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKV 206
RF R +L + ES P +RF +E A D D+GAN+ Y L+P+E+F+LD+K +E +
Sbjct: 131 RFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNF 190
Query: 207 LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266
LELVLRK LDRE+ H L++ A DGG P +GT Q+ + VLD NDN+P FD+S Y V+L
Sbjct: 191 LELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRL 250
Query: 267 REDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE 326
E++P GTLV+KLNASD DEG N E+ Y S+ D + F I+++TGE++V G LDYE
Sbjct: 251 LENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYE 310
Query: 327 EASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAV 386
+ +SY+I + A D+ P++GHCKV+V ++DVNDN PE+ +T L+ PV E+A +T++A+
Sbjct: 311 DYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIAL 370
Query: 387 LSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGG 445
+SV+D+DSG N +V+ L +PF+L + F N Y+LV+ LDRE V+VY + VTA DGG
Sbjct: 371 ISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGG 430
Query: 446 IPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVT 505
P L + ++ VE++D+NDN P+F + Y+++++ENN PG + TV A D D +ENA V+
Sbjct: 431 SPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVS 490
Query: 506 YSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTA 565
YSL+ER + P++SYVS+++ SG +YA+ D+E+ V A+D G PPL S VT
Sbjct: 491 YSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTL 550
Query: 566 NVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL 624
V+V+D ND+AP +L P A E+VPR+ AG++V KV A+D DSG NAWL Y L
Sbjct: 551 QVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYEL 610
Query: 625 --AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682
A S F+V L+TGEI TTR + + L V+V+D+GEP L+A+ + V++V+
Sbjct: 611 QPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVE 670
Query: 683 --RVSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGT 739
+ K P ++ +YLIIA+ VS + +LT+++ + ++C
Sbjct: 671 SGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEAV 730
Query: 740 ACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTA 799
G P L A G+ S ++ + C
Sbjct: 731 CTRG--------KPTLLCSSA---------------------VGSWSYSQQRRQRVCSGE 761
Query: 800 GSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQP 859
M ++ GP + + + + L+ + + P P
Sbjct: 762 APPKTDLMAFSPSLPQGPTSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGP 821
Query: 860 NPDW-------------RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 906
+ W S + AG++S+ + + GPG P Q P
Sbjct: 822 DQQWPTVSSATPEPEAGEVSPPVGAGVNSN-----SWTFKYGPGNPKQSGP--------- 867
Query: 907 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 966
GE+ PG+P + P I S I ++E T
Sbjct: 868 --GELPDKF------------IIPGSPAIISIRQEPTNSQIDKSDFITFGKKEET----- 908
Query: 967 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007
KK++ K KKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 909 --------KKKKKK-----KKGNKTQEKKEKGNSTTDNSDQ 936
>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 621 bits (1602), Expect = e-178
Identities = 359/834 (43%), Positives = 505/834 (60%), Gaps = 45/834 (5%)
Query: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
LLL LL L G AA+Q+RYS+PEE G+ VGN+ + LGLE + L +RI G
Sbjct: 15 LLLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRM-- 72
Query: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
+ L+ +G+L RIDRE LC Q PRCL+S +L + + + VEVEI+DINDN+PR
Sbjct: 73 QLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPR 132
Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
F + ++++ E+ AP +RF + DPDVG NS+Q ++LS + HF +D++ K
Sbjct: 133 FLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYP 192
Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
ELVL LDRE A++ LVLTA+DGG P RS AQI V VLD NDN+P F Q YRV +
Sbjct: 193 ELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVP 252
Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
E+ P GT V+ + A+D DEG +GE+ YS T ++ Q+F ++ TGE+ LDYE+
Sbjct: 253 ENLPVGTPVLAVTATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEISTSANLDYED 311
Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
+S Y++ V+A D GP + KVL+ I+DVNDN PEVV+T + E+A P T++A+
Sbjct: 312 SSFYELGVEARD-GP-GLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALF 369
Query: 388 SVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGI 446
V D+DSG N V+ + +LPF L GN Y LV + LDRE V +YNITVTATD G
Sbjct: 370 QVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGT 429
Query: 447 PQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTY 506
P L++ + + ++D NDNPP+F SYS+Y+ ENN G + +V A DPD +NA+V+Y
Sbjct: 430 PPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSY 489
Query: 507 SLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTAN 566
SL E +QG P++SYVSINS +G LYA+ SFDYE+ R+ + V A D G PPLSS V+ +
Sbjct: 490 SLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLS 549
Query: 567 VYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLA 625
++V+D ND+AP ILYP T+ S E+ PR+A GYLVTKV+A+D DSGQNAWL Y L
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 626 QTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVS 685
+ S+ LF V LHTGE+RT R + D +L V V+D+G+P LSA+V +TVAV DR+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIP 669
Query: 686 KILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGG 744
IL D S + S++TLYL++A++ VS +FL +I+L ++ R+
Sbjct: 670 DILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRW---------- 719
Query: 745 FCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSD 804
QA+ A +P HF+ V G + +TY ++ LTA S
Sbjct: 720 --------HKSRLLQASGGGLASMPGS-----HFVGVEGVRAFLQTYSHEVSLTADSRKS 766
Query: 805 TFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQ 858
+F P P+ A + +S + + L+I ++ ++ EPRQ
Sbjct: 767 HLIF--------PQPNYADTLINQ------ESYEKSEPLLITQDLLETKGEPRQ 806
>gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 620 bits (1600), Expect = e-177
Identities = 360/973 (36%), Positives = 552/973 (56%), Gaps = 63/973 (6%)
Query: 22 WLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINH 81
WL +L L LL L PG Q+RYS+PEE A ++VGN+A+ LGL +R L LR++
Sbjct: 13 WLQVL--LPFLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVS- 69
Query: 82 LGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDI 141
Y ++ SG L V++RIDRE +C ++P C+L + +A NP+ + + V + DI
Sbjct: 70 ---AEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDI 126
Query: 142 NDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQ 201
NDN+P F + L++ ES PG F ++ A D DVG NS+Q Y L+ +E+F+L K
Sbjct: 127 NDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTP 186
Query: 202 ENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQST 261
+ K EL+L+ LDRE+ +LH LVLTAVDGG P +SGT QI ++V D NDN P F Q
Sbjct: 187 DGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDV 246
Query: 262 YRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIG 321
YRV LRED PPG V+++ A+D DEG N E+ YS + ++ + F+++ TGE+
Sbjct: 247 YRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHN-VDEQVKHFFNLNEKTGEITTKD 305
Query: 322 GLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPN 381
LD+E ASSY + ++A D P +A HC + V+I+D ND APEV++T + +P+PE++ P
Sbjct: 306 DLDFEIASSYTLSIEAKD--PGDLAAHCSIQVEILDDNDCAPEVIVTSVSTPLPEDSPPG 363
Query: 382 TIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFG-NSYTLVVSGPLDRERVAVYNITVT 440
T++A++ D+DSG N +V + F L N Y LV G LDRE + YN+T+T
Sbjct: 364 TVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTIT 423
Query: 441 ATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKE 500
ATDGG P L+S + + ISD+NDN P F + SY +++ ENN PG + + A+DPD
Sbjct: 424 ATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGP 483
Query: 501 NAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLS 560
+ +V+YS++ +++ + SYVS+++ SG ++A +FD+E+ R F +T++A+D+GSP LS
Sbjct: 484 SGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALS 543
Query: 561 STVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAW 619
+ V+ V V D+ND+AP +LYP + SA F+MVPR A GYLVTKV+A+D+DSG NAW
Sbjct: 544 ANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAW 603
Query: 620 LFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVA 679
L YH+ Q S+ LF + L TGE+RT R +GD + L V VRD G+P LSA+ + +
Sbjct: 604 LSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLI 663
Query: 680 VVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGT 739
D + ++LPD + +++ YL++AL+ +S +F L +I+ ++
Sbjct: 664 FADSLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVILAISLR--------- 714
Query: 740 ACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTA 799
+R S ++ + + ++ G V P++ E T Y Y C+ +
Sbjct: 715 --------LRLSSRSDAWDCFQPGLSSK--PGPGVLPNYSEG------TLPYSYNLCVAS 758
Query: 800 GSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQP 859
S F F N + P AQ V D+ + + A + + + Q P
Sbjct: 759 QSAKTEFNFLNITPELVP----AQDLVCDNASWEQNTNHGAAGVPFASDTILKQ---APP 811
Query: 860 NPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVS 912
N DWR+S + R G S + ++ G P+ Q+ T ++SA+ EA + S
Sbjct: 812 NTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGS 862
Query: 913 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFIT 972
+G G + + +YGP Q P + IPGS A ++ + K+
Sbjct: 863 STLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGG 918
Query: 973 FGKKEETKKKKKK 985
G K+++ KK+KK
Sbjct: 919 NGNKKKSGKKEKK 931
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,814,001
Number of Sequences: 37866
Number of extensions: 2144874
Number of successful extensions: 15899
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 212
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 7755
Number of HSP's gapped (non-prelim): 1204
length of query: 1007
length of database: 18,247,518
effective HSP length: 112
effective length of query: 895
effective length of database: 14,006,526
effective search space: 12535840770
effective search space used: 12535840770
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.